SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes.
The SUPERFAMILY annotation is based on a collection of hidden Markov models, which represent structural protein domains at the SCOP superfamily level. A superfamily groups together domains which have an evolutionary relationship. The annotation is produced by scanning protein sequences from over 3,200 completely sequenced genomes against the hidden Markov models.
SUPERFAMILY 1.75 can be accessed from legacy-supfam.orgLearn more »
Paste a protein sequence in FASTA format, or visit the full search page for more options
Browse the SCOP hierarchy
Browse a tree of all the SUPERFAMILY genomes
View a variety of statistics on the structural assignment of 3,200 genomes