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Enzyme Commission (EC): Histone-lysine N-methyltransferase 

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Root: EC Hierarchy (from IntEnz release 70)

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EC term [EC ID] <#Children> #Domains
(Superfamily|Family)
#Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <6>
+ + + 3:   Transferases [2] <10>(446|676) (446|529|266)
+ + 2:   Transferring one-carbon groups [2.1] <5>(85|124) (85|76|29)
+ 1:   Methyltransferases [2.1.1] <355>(66|102) (66|58|13)
0:   Histone-lysine N-methyltransferase [2.1.1.43](17|17) (17|14|4)

Superfamily

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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
DNA-binding domain0Direct
Tudor/PWWP/MBT0Direct
Chromo domain-like0Direct
KRAB domain (Kruppel-associated box)0Direct
FYVE/PHD zinc finger0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
WW domain0Direct
RuBisCo LSMT C-terminal, substrate-binding domain0Direct
RNA-binding domain, RBD0Direct
HMG-box0Direct
SET domain0Direct
beta-beta-alpha zinc fingers7.407e-16Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.000000000000181Direct
TPR-like0.000000000003256Direct
Bromodomain0.0000000001418Direct
Ankyrin repeat0.000005185Direct
PUA domain-like0.0001017Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Family

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Family

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SCOP term FDR (all) Annotation (direct or inherited)
PHD domain0Direct
Histone lysine methyltransferases0Direct
Catalytic, N-terminal domain of histone methyltransferase Dot1l0Direct
HMG-box0Direct
WW domain0Direct
RuBisCo LSMT catalytic domain0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
KRAB domain (Kruppel-associated box)0Direct
PWWP domain0Direct
RuBisCo LSMT C-terminal, substrate-binding domain0Direct
Chromo domain0Direct
SRA domain-like0Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.00000000000003185Direct
Canonical RBD0.00000000001287Direct
Classic zinc finger, C2H20.00000000004047Direct
Bromodomain0.00000000004096Direct
Ankyrin repeat0.000001778Direct

LINKTO: Domain2BO Download and Domain2BO Algorithm

Supra-domain (Single|Duplex|Triple)

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Supra-domain (Single)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Chromo domain-like0Direct
KRAB domain (Kruppel-associated box)0Direct
RNA-binding domain, RBD0Direct
RuBisCo LSMT C-terminal, substrate-binding domain0Direct
Tudor/PWWP/MBT0Direct
Conserved domain common to transcription factors TFIIS, elongin A, CRSP700Direct
SET domain0Direct
FYVE/PHD zinc finger0Direct
WW domain0Direct
DNA-binding domain0Direct
HMG-box0Direct
beta-beta-alpha zinc fingers5.248e-16Direct
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.000000000000131Direct
TPR-like0.000000000002384Direct
Bromodomain0.0000000001061Direct
Ankyrin repeat0.000004125Direct
PUA domain-like0.00008289Direct

LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

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Supra-domain (Duplex) in N- to C-terminal order

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57903,82199
  • 57903 - FYVE/PHD zinc finger
  • 82199 - SET domain
  • 0Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    88697,82199
  • 88697 - PUA domain-like
  • 82199 - SET domain
  • 0Direct
    82185,82199
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82199 - SET domain
  • 0Direct
    82199,81822
  • 82199 - SET domain
  • 81822 - RuBisCo LSMT C-terminal, substrate-binding domain
  • 0Direct
    54171,82199
  • 54171 - DNA-binding domain
  • 82199 - SET domain
  • 0Direct
    82199,48452
  • 82199 - SET domain
  • 48452 - TPR-like
  • 0Direct
    82199,57903
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    63748,82199
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0Direct
    48403,82199
  • 48403 - Ankyrin repeat
  • 82199 - SET domain
  • 0Direct
    57903,63748
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 0Direct
    54160,82199
  • 54160 - Chromo domain-like
  • 82199 - SET domain
  • 0Direct
    57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0Direct
    57903,47370
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0.0000000008724Direct

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

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    Supra-domain (Triple) in N- to C-terminal order

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57903,63748,82199
  • 57903 - FYVE/PHD zinc finger
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 0Direct
    57903,57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    63748,82199,57903
  • 63748 - Tudor/PWWP/MBT
  • 82199 - SET domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    57667,57667,57667
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 57667 - beta-beta-alpha zinc fingers
  • 0.000000000001374Direct

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Distribution on sTOL

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