dcGO - A comprehensive domain-centric ontology resource for post-genomic research on functions, phenotypes, diseases and more   
  
  

Worm Phenotype (WP): early embryonic lethal 

(show info)

Jump to [ Top · Hierarchy · Annotations ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term
(+ for parents, - for children)
WP term [WP ID] <#Children> #Domains
(Superfamily|Family)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   development variant [WBPhenotype:0000518] <4>(511|586) (511|253|70)
+ + + 3:   organism development variant [WBPhenotype:0000531] <10>(505|584) (505|253|70)
+ + 2:   embryonic development variant [WBPhenotype:0000749] <21>(453|543) (453|238|67)
+ + 2:   lethal [WBPhenotype:0000062] <5>(502|582) (502|253|70)
+ 1:   embryonic lethal [WBPhenotype:0000050] <7>(451|542) (451|238|67)
0:   early embryonic lethal [WBPhenotype:0001100] <24>(41|39) (43|14|3)
- 1:   aster defective early emb [WBPhenotype:0001110] <3>(0|0) (0|0|0)
- 1:   cytokinesis defective early emb [WBPhenotype:0001078] <3>(5|8) (6|0|0)
- 1:   cell position defective early emb [WBPhenotype:0001118] <2>(1|0) (1|0|0)
- 1:   cytoplasmic appearance defective early emb [WBPhenotype:0000769] <2>(6|6) (6|2|0)
- 1:   egg integrity defective early emb [WBPhenotype:0001178] <2>(2|2) (3|1|0)
- 1:   embryonic morphology defective early emb [WBPhenotype:0001135] <2>(0|0) (0|0|0)
- 1:   other abnormality early emb [WBPhenotype:0001007] <2>(11|6) (11|2|1)
- 1:   polar body defective early emb [WBPhenotype:0001147] <2>(2|2) (2|1|0)
- 1:   pronuclear nuclear appearance defective early emb [WBPhenotype:0001034] <2>(7|10) (9|4|0)
- 1:   pseudocleavage defective early emb [WBPhenotype:0001167] <2>(0|0) (0|0|0)
- 1:   spindle defective early emb [WBPhenotype:0000759] <2>(7|11) (7|4|0)
- 1:   cell cell contacts defective early emb [WBPhenotype:0001117] <1>(2|1) (2|0|0)
- 1:   cell cycle defective early emb [WBPhenotype:0001114] <1>(2|2) (2|0|0)
- 1:   embryonic developmental delay early emb [WBPhenotype:0001185] <1>(0|0) (0|0|0)
- 1:   meiosis defective early emb [WBPhenotype:0001041] <1>(3|3) (3|0|0)
- 1:   Aba ABp division axis defective early emb [WBPhenotype:0001134](1|1) (1|1|0)
- 1:   asymmetric cell division defective early emb [WBPhenotype:0000748](0|0) (0|0|0)
- 1:   centrosome attachment defective early emb [WBPhenotype:0000771](0|0) (0|0|0)
- 1:   chromosome segregation variant karyomeres early emb [WBPhenotype:0001077](1|1) (1|1|0)
- 1:   cortical dynamics defective early emb [WBPhenotype:0001044](0|0) (0|0|0)
- 1:   egg size defective early emb [WBPhenotype:0000044](0|0) (0|0|0)
- 1:   integrity of membranous organelles defective early emb [WBPhenotype:0000767](0|0) (0|0|0)
- 1:   interphase entry defective early emb [WBPhenotype:0001043](0|0) (0|0|0)
- 1:   one cell arrest early emb [WBPhenotype:0000040](2|3) (2|0|0)

Superfamily

Jump to [ Top · Hierarchy ]

Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
P-loop containing nucleoside triphosphate hydrolases0Direct
Histone-fold0Direct
Skp1 dimerisation domain-like4.451e-16Direct
ARM repeat0.0000000000003873Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000000000001064Direct
Nucleic acid-binding proteins0.0000000001453Direct
GroEL-intermediate domain like0.000000000168Direct
GroEL equatorial domain-like0.000000000168Direct
GroEL apical domain-like0.000000001553Direct
Zn-binding ribosomal proteins0.00000003248Direct
Class II aaRS and biotin synthetases0.00000007367Direct
Translation proteins SH3-like domain0.0000008376Direct
Tubulin C-terminal domain-like0.000002188Direct
Cyclin-like0.000005147Direct
S15/NS1 RNA-binding domain0.000005995Direct
Prefoldin0.00001033Direct
"Winged helix" DNA-binding domain0.00001147Direct
Tubulin nucleotide-binding domain-like0.00001579Direct
Sm-like ribonucleoproteins0.00004594Direct
TPR-like0.000047Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00007926Direct
Cdc48 domain 2-like0.00007926Direct
ADC-like0.00007926Direct
Activating enzymes of the ubiquitin-like proteins0.00025Direct
Class II aaRS ABD-related0.00025Direct
WD40 repeat-like0.0003261Direct
CAD & PB1 domains0.0003524Direct
L30e-like0.0005127Direct
Translation proteins0.0006519Direct
Translational machinery components0.0009511Direct
Smc hinge domain0.0009511Direct
Calponin-homology domain, CH-domain0.001894Inherited
Nucleotidylyl transferase0.00563Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01308Inherited
Invertebrate chitin-binding proteins0.01804Inherited
DNA/RNA polymerases0.03092Inherited
GTPase activation domain, GAP0.03492Inherited
POZ domain0.03566Inherited
UBC-like0.1744Inherited
BAR/IMD domain-like0.2071Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3026Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Family

Jump to [ Top · Hierarchy ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Proteasome subunits0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
a tRNA synthase domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
Nucleosome core histones0Direct
Skp1 dimerisation domain-like0.000000000000002511Direct
Extended AAA-ATPase domain0.00000000001357Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000000007969Direct
Armadillo repeat0.000000003854Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.0000001043Direct
Cyclin0.0000001043Direct
BTB/POZ domain0.000003409Direct
Motor proteins0.000004707Direct
Prefoldin0.000007122Direct
Tubulin, C-terminal domain0.000009175Direct
Ubiquitin activating enzymes (UBA)0.00001246Direct
Pumilio repeat0.00002246Direct
Tubulin, GTPase domain0.00005402Direct
Cdc48 N-terminal domain-like0.0001352Direct
Cdc48 domain 2-like0.0001352Direct
G proteins0.0001797Direct
Translational machinery components0.0005029Direct
DEP domain0.0005967Direct
Smc hinge domain0.0005967Direct
L30e/L7ae ribosomal proteins0.0005967Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.000956Direct
Cold shock DNA-binding domain-like0.0009948Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.001109Inherited
Actin/HSP700.001462Inherited
WD40-repeat0.001864Inherited
DNA polymerase I0.003372Inherited
Calponin-homology domain, CH-domain0.005429Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01505Inherited
BCR-homology GTPase activation domain (BH-domain)0.06253Inherited
PDZ domain0.09249Inherited
UBC-related0.3002Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3492Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Supra-domain (Single|Duplex|Triple)

Jump to [ Top · Hierarchy ]

Supra-domain (Single)

(
show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Histone-fold0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Skp1 dimerisation domain-like3.47e-16Direct
ARM repeat0.0000000000003034Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000000000008346Direct
Nucleic acid-binding proteins0.0000000001147Direct
GroEL equatorial domain-like0.0000000001326Direct
GroEL-intermediate domain like0.0000000001326Direct
GroEL apical domain-like0.000000001231Direct
Zn-binding ribosomal proteins0.00000002588Direct
Class II aaRS and biotin synthetases0.00000005881Direct
Translation proteins SH3-like domain0.0000006737Direct
Tubulin C-terminal domain-like0.000001766Direct
Cyclin-like0.000004161Direct
S15/NS1 RNA-binding domain0.000004848Direct
Prefoldin0.000008357Direct
"Winged helix" DNA-binding domain0.000009288Direct
Tubulin nucleotide-binding domain-like0.0000128Direct
Sm-like ribonucleoproteins0.00003737Direct
TPR-like0.00003824Direct
Cdc48 domain 2-like0.00006461Direct
ADC-like0.00006461Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00006461Direct
Activating enzymes of the ubiquitin-like proteins0.0002048Direct
Class II aaRS ABD-related0.0002048Direct
WD40 repeat-like0.0002675Direct
CAD & PB1 domains0.0002893Direct
L30e-like0.0004223Direct
Translation proteins0.0005383Direct
Smc hinge domain0.0007877Direct
Translational machinery components0.0007877Direct
Calponin-homology domain, CH-domain0.001582Inherited
Nucleotidylyl transferase0.004771Inherited
Actin-like ATPase domain0.007831Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01124Inherited
Invertebrate chitin-binding proteins0.0156Inherited
DNA/RNA polymerases0.02702Inherited
GTPase activation domain, GAP0.03058Inherited
POZ domain0.03125Inherited
UBC-like0.1596Inherited
BAR/IMD domain-like0.1907Inherited
HAD-like0.2186Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2827Inherited

LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

Jump to [ Top · Hierarchy ]

Supra-domain (Duplex) in N- to C-terminal order

(
show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 6.937e-16Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000000001326Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000000001326Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000003495Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0000128Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0000128Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.00006461Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0002843Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.0007877Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.003095Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1439Inherited

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Jump to [ Top · Hierarchy ]

    Supra-domain (Triple) in N- to C-terminal order

    (
    show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000000001326Direct

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Distribution on sTOL

    Plot distribution on species Tree Of Life (sTOL) for Superfamily and/or Family domains annotated by this WP term
    Plot tree as:   Download Newick format tree:
    (show help)
    Plot distribution on species Tree Of Life (sTOL) for single supra-domains annotated by this WP term
    Plot tree as:   Download Newick format tree:   Browsing in TREE OF LIFE:
    (show help)