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Worm Phenotype (WP): early embryonic lethal 

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

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WP term [WP ID] <#Children> #Domains
(Superfamily|Family)
#Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <5>
+ + + + 4:   development variant [WBPhenotype:0000518] <4>(511|585) (511|252|70)
+ + + 3:   organism development variant [WBPhenotype:0000531] <10>(506|583) (506|252|70)
+ + 2:   lethal [WBPhenotype:0000062] <5>(502|581) (502|252|70)
+ + 2:   embryonic development variant [WBPhenotype:0000749] <21>(465|549) (465|241|67)
+ 1:   embryonic lethal [WBPhenotype:0000050] <7>(462|548) (462|240|67)
0:   early embryonic lethal [WBPhenotype:0001100] <24>(39|38) (40|12|3)
- 1:   aster defective early emb [WBPhenotype:0001110] <3>(0|0) (0|0|0)
- 1:   cytokinesis defective early emb [WBPhenotype:0001078] <3>(5|8) (5|0|0)
- 1:   cell position defective early emb [WBPhenotype:0001118] <2>(1|0) (1|0|0)
- 1:   cytoplasmic appearance defective early emb [WBPhenotype:0000769] <2>(6|6) (6|2|0)
- 1:   egg integrity defective early emb [WBPhenotype:0001178] <2>(2|2) (4|1|0)
- 1:   embryonic morphology defective early emb [WBPhenotype:0001135] <2>(0|0) (0|0|0)
- 1:   other abnormality early emb [WBPhenotype:0001007] <2>(11|6) (11|2|1)
- 1:   polar body defective early emb [WBPhenotype:0001147] <2>(2|2) (2|1|0)
- 1:   pronuclear nuclear appearance defective early emb [WBPhenotype:0001034] <2>(6|9) (6|2|0)
- 1:   pseudocleavage defective early emb [WBPhenotype:0001167] <2>(0|0) (0|0|0)
- 1:   spindle defective early emb [WBPhenotype:0000759] <2>(7|11) (7|3|0)
- 1:   cell cell contacts defective early emb [WBPhenotype:0001117] <1>(2|1) (2|0|0)
- 1:   cell cycle defective early emb [WBPhenotype:0001114] <1>(2|2) (2|0|0)
- 1:   embryonic developmental delay early emb [WBPhenotype:0001185] <1>(0|0) (0|0|0)
- 1:   meiosis defective early emb [WBPhenotype:0001041] <1>(3|3) (3|0|0)
- 1:   Aba ABp division axis defective early emb [WBPhenotype:0001134](1|1) (1|1|0)
- 1:   asymmetric cell division defective early emb [WBPhenotype:0000748](0|0) (0|0|0)
- 1:   centrosome attachment defective early emb [WBPhenotype:0000771](0|0) (0|0|0)
- 1:   chromosome segregation variant karyomeres early emb [WBPhenotype:0001077](1|1) (1|1|0)
- 1:   cortical dynamics defective early emb [WBPhenotype:0001044](0|0) (0|0|0)
- 1:   egg size defective early emb [WBPhenotype:0000044](0|0) (0|0|0)
- 1:   integrity of membranous organelles defective early emb [WBPhenotype:0000767](0|0) (0|0|0)
- 1:   interphase entry defective early emb [WBPhenotype:0001043](0|0) (0|0|0)
- 1:   one cell arrest early emb [WBPhenotype:0000040](2|3) (2|0|0)

Superfamily

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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
P-loop containing nucleoside triphosphate hydrolases0Direct
Histone-fold0Direct
Skp1 dimerisation domain-like4.342e-16Direct
ARM repeat0.0000000000002996Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000000000008457Direct
Nucleic acid-binding proteins0.000000000118Direct
GroEL equatorial domain-like0.0000000001464Direct
GroEL-intermediate domain like0.0000000001464Direct
GroEL apical domain-like0.000000001356Direct
Zn-binding ribosomal proteins0.00000002909Direct
Class II aaRS and biotin synthetases0.00000006319Direct
Translation proteins SH3-like domain0.0000007424Direct
Tubulin C-terminal domain-like0.000001923Direct
Cyclin-like0.000004446Direct
S15/NS1 RNA-binding domain0.000005504Direct
"Winged helix" DNA-binding domain0.000008164Direct
Prefoldin0.000009374Direct
Tubulin nucleotide-binding domain-like0.00001407Direct
Sm-like ribonucleoproteins0.00004102Direct
ADC-like0.00007393Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.00007393Direct
Cdc48 domain 2-like0.00007393Direct
TPR-like0.0001199Direct
WD40 repeat-like0.0001815Direct
Class II aaRS ABD-related0.0002309Direct
Activating enzymes of the ubiquitin-like proteins0.0002309Direct
CAD & PB1 domains0.0003289Direct
L30e-like0.0004739Direct
Translation proteins0.0005882Direct
Smc hinge domain0.0008904Direct
Translational machinery components0.0008904Direct
Calponin-homology domain, CH-domain0.001718Inherited
Nucleotidylyl transferase0.005175Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01237Inherited
Invertebrate chitin-binding proteins0.0171Inherited
POZ domain0.0315Inherited
GTPase activation domain, GAP0.0332Inherited
UBC-like0.1672Inherited
Multidrug efflux transporter AcrB transmembrane domain0.294Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Family

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Family

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SCOP term FDR (all) Annotation (direct or inherited)
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
Proteasome subunits0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Nucleosome core histones0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
a tRNA synthase domain0Direct
Skp1 dimerisation domain-like0.000000000000001854Direct
Extended AAA-ATPase domain0.000000000006083Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000000007209Direct
Armadillo repeat0.000000003464Direct
Cyclin0.00000009322Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.00000009322Direct
BTB/POZ domain0.000002924Direct
Motor proteins0.000004155Direct
Prefoldin0.000006647Direct
Tubulin, C-terminal domain0.000008382Direct
Ubiquitin activating enzymes (UBA)0.00001174Direct
Pumilio repeat0.00002086Direct
Tubulin, GTPase domain0.00004985Direct
Cdc48 domain 2-like0.0001285Direct
Cdc48 N-terminal domain-like0.0001285Direct
G proteins0.0001526Direct
Translational machinery components0.0004761Direct
DEP domain0.0005694Direct
L30e/L7ae ribosomal proteins0.0005694Direct
Smc hinge domain0.0005694Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0009005Direct
Cold shock DNA-binding domain-like0.0009401Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.001038Inherited
WD40-repeat0.001184Inherited
Actin/HSP700.001362Inherited
Calponin-homology domain, CH-domain0.005082Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01447Inherited
BCR-homology GTPase activation domain (BH-domain)0.06053Inherited
PDZ domain0.0785Inherited
UBC-related0.2938Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3421Inherited

LINKTO: Domain2BO Download and Domain2BO Algorithm

Supra-domain (Single|Duplex|Triple)

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Supra-domain (Single)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
P-loop containing nucleoside triphosphate hydrolases0Direct
Histone-fold0Direct
Skp1 dimerisation domain-like3.404e-16Direct
ARM repeat0.0000000000002358Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000000000006665Direct
Nucleic acid-binding proteins0.00000000009351Direct
GroEL equatorial domain-like0.0000000001161Direct
GroEL-intermediate domain like0.0000000001161Direct
GroEL apical domain-like0.000000001079Direct
Zn-binding ribosomal proteins0.00000002327Direct
Class II aaRS and biotin synthetases0.00000005065Direct
Translation proteins SH3-like domain0.0000005999Direct
Tubulin C-terminal domain-like0.00000156Direct
Cyclin-like0.000003614Direct
S15/NS1 RNA-binding domain0.000004476Direct
"Winged helix" DNA-binding domain0.000006643Direct
Prefoldin0.000007626Direct
Tubulin nucleotide-binding domain-like0.00001146Direct
Sm-like ribonucleoproteins0.00003352Direct
Cdc48 domain 2-like0.0000605Direct
DNA ligase/mRNA capping enzyme, catalytic domain0.0000605Direct
ADC-like0.0000605Direct
TPR-like0.00009827Direct
WD40 repeat-like0.0001491Direct
Class II aaRS ABD-related0.0001899Direct
Activating enzymes of the ubiquitin-like proteins0.0001899Direct
CAD & PB1 domains0.0002713Direct
L30e-like0.0003921Direct
Translation proteins0.0004875Direct
Smc hinge domain0.0007405Direct
Translational machinery components0.0007405Direct
Calponin-homology domain, CH-domain0.001439Inherited
Nucleotidylyl transferase0.004397Inherited
Actin-like ATPase domain0.007211Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01066Inherited
Invertebrate chitin-binding proteins0.01482Inherited
POZ domain0.02759Inherited
GTPase activation domain, GAP0.02911Inherited
UBC-like0.1528Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2747Inherited

LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

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Supra-domain (Duplex) in N- to C-terminal order

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 6.804e-16Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000000001161Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000000001161Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000003123Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.00001146Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00001146Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.0000605Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.002826Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1425Inherited

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

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    Supra-domain (Triple) in N- to C-terminal order

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000000001161Direct

    LINKTO: Supra-domain2BO Download and Supra-domain2BO Algorithm

    Distribution on sTOL

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