|
ENSRNOP00000064073 (Rattus norvegicus 76_5.0)
(show help)
For a sequence (see Protein sequence) in target, dcGO predictor has the following procedures to predict the ontology terms of the target:
First, obtain Domain architecture and its residual domains and supra-domains from the SUPERFAMILY database.
Then, use the domain-centric annotations to predict the ontology terms of the target:
- If a target contained a domain/supra-domain, then all ontology terms associated to that domain/supra-domain are transferred to the target (together with hypergeometric score, h-score);
- When a target-to-term transfer is supported by one or more residential domains/supra-domains, sum up h-scores to calculate predictive score (p-score);
- The p-score is then rescaled to the range of 0-1. For each namespace (e.g., three sub-ontologies for GO), p-score=(SUM-MIN)/(MAX-MIN), where SUM is the sum of all h-scores to support a term transferred to the target, MIN and MAX are respectively the minimum and maximum of SUM over a whole list of predicted terms for the target;
Finally, the predictive score being rescaled is used to rank the predictions. The higher value of the p-score indicates the more evident the prediction is. In the dcGO, each ontology has a slim version on its own, containing ontological terms at four levels of increasing granularity (that is, being highly general, general, specific, and highly specific). Listed in the table are the top 5 predictions for each specificity and for each namespace. In addition to those restricted by the term specificity, i.e., Export prediction (slim version), the full list of predictions are also provided for the download, i.e., Export prediction (full version).
Protein sequence
Comment |
pep:novel chromosome:Rnor_5.0:2:229554811:229557675:-1 gene:ENSRNOG00000047499 transcript:ENSRNOT00000070994 gene_biotype:protein_coding transcript_biotype:protein_coding |
Sequence length |
955 |
Sequence |
MRSAGREPLPRRSPRWRRASPLCETSAGWRVSQLRRDDLRRPSTMKGKERSPVKPKRSRG
GEDSSSRGERSKKLGGSGGSNGSSSGKTDSGGSRRSLHLDKSSSRGGSREYDTGGGSSSS
RLHSYSSPSTKNSSGGGESRSSSRGGGGESRSSGAASSAPGGGDGVEYKTLKISELGSQL
SDEAVEDGLFHEFKRFGDVSVKISHLSGSGSGDERVAFVNFRRPEDARAAKHARGRLVLY
DRPLKIEAVYVSRRRSRSPLDKDTYAPSSSVVGSSVGSHRHAPGGGGGQRSLSPGGAALG
YRDYRLQQLALGRLPPPPPPPLPRELERERDYPFYDRVRPAYSLEPRVGAGAGAAPFREV
DEISPEDDQRANRTLFLGNLDITVTENDLRRAFDRFGVITEVDIKRPSRGQTSTYGFLKF
ENLDMSHRAKIAMSGKIIIRNPIKIGYGKATPTTRLWVGGLGPWVPLAALAREFDRFGTI
RTIDYRKGDSWAYIQYESLDAAHAAWTHMRGFPLGGPDRRLRVDFADTEHRYQQQYLQPL
PLTHYELVTDTFGHRAPDPLRSARDRTPPLLYRDRDRDLYPDSDWVPPPPPVRERSARAA
TSAVTAYEPLDSLDRRRDGWSLDRDRGDRDLPSSRDQPRKRRLPEESGGRHLDRSPESDR
PRKQRHCTPSPDRSPELSSNRDRYNSDNDRSSRLLLLERPSPVRDRRGSLEKSQSDKRDR
KNSASAERDRKHRTAAPTEGKTPLKKEDRSDGNTPSASTSSSKQKPPSQKQDGGTAPVAA
SSPKLCLAWQGMLLLKNSNFPSNMHLLQGDLQVASSLLVEGSTGGKVAQLKITQRLRLDQ
PKLDEVTRRIKVAGPNGYAILLAVPGSSDSRSSSSSATSDTAASTQRPLRNLVSYLKQKQ
AAGVISLPVGGNKDKENTGVLHAFPPCEFSQQFLDSPAKALAKSEEDYLVMIIVR
|
Jump to [ Top · Protein sequence · Domain architecture ]
Domain architecture

1
Jump to [ Top · Protein sequence · Domain architecture ]
|
  
|