dcGO - A comprehensive domain-centric ontology resource for post-genomic research on functions, phenotypes, diseases and more   
  
  

Faceted search: A hub to mine the dcGO resource

    Search results will be organized with links provided to the relevant pages, including one or more (if found) of:
    • SCOP Hierarchy for SCOP domains and their annotations;
    • GO Hierarchy for GO terms and their annotated domains/supra-domains;
    • BO Hierarchy for terms from Biomedical Ontologies that are not GO, and domains/supra-domains being annotated;
    • PSnet for similar phenotypes based on shared domain annotations;
    • sTOL for the distribution of individual domain and GO/BO-annotated domains over the tree, and enriched GO/BO terms for extant and ancestral genomes;
    • dcGO Predictor for function, phenotype and disease predictions of over 60 million sequences including more than 2,000 genomes and UniProt and hundreds of meta-genomes.
    • dcGO Enrichment for function, phenotype and disease enrichment for a list of protein domains submitted.
    • dcGO Pevo for exploring architecture plasticity potentials of input dcGO terms during eukaryotic evolution.

Quick start to mining the dcGO resource

  • SCOP domains (LINKTO SCOP Hierarchy and sTOL)
    • SCOP unique identifier (sunid) of a SCOP, e.g. 46458
    • SCOP name or part thereof, e.g. hemoglobin
    • Enrichment analysis for a list of input protein domains via dcGO Enrichment.
  • Genomes (LINKTO SUPERFAMILY database and sTOL)
    • A common organism name, e.g. human
    • A genome name or part thereof, e.g. Homo sapiens

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