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Domain combination pairs in Alcanivorax borkumensis SK2

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

611 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2811
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2313
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 224
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 154
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 141
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 142
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 136
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 128
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 124
Homodimeric domain of signal transducing histidine kinase CheY-like 117
Actin-like ATPase domain Actin-like ATPase domain 114
CheY-like C-terminal effector domain of the bipartite response regulators 112
Thiolase-like Thiolase-like 103
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 105
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 94
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 94
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 94
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 94
PreATP-grasp domain Rudiment single hybrid motif 73
GroES-like NAD(P)-binding Rossmann-fold domains 72
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 73
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 63
P-loop containing nucleoside triphosphate hydrolases Translation proteins 65
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 63
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 63
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 63
Thioredoxin-like GST C-terminal domain-like 62
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 62
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 65
ACT-like ACT-like 54
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 52
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 55
Alpha-L RNA-binding motif Pseudouridine synthase 51
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 55
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 54
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 52
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 53
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 52
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 41
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 43
Triger factor/SurA peptide-binding domain-like FKBP-like 44
Phospholipase D/nuclease Phospholipase D/nuclease 43
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
PYP-like sensor domain (PAS domain) Nucleotide cyclase 44
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 43
CheY-like P-loop containing nucleoside triphosphate hydrolases 42
CoA-dependent acyltransferases CoA-dependent acyltransferases 44
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
PurM N-terminal domain-like PurM C-terminal domain-like 43
Nucleic acid-binding proteins Nucleic acid-binding proteins 43
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
CheY-like Homeodomain-like 43
Lysozyme-like beta-lactamase/transpeptidase-like 43
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 41
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 33
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 31
Calcium ATPase, transduction domain A HAD-like 33
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 33
Nucleotide cyclase EAL domain-like 33
EF-G C-terminal domain-like EF-G C-terminal domain-like 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 33
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 33
CheY-like CheY-like 32
Acetyl-CoA synthetase-like ACP-like 33
PreATP-grasp domain Single hybrid motif 32
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 32
Rudiment single hybrid motif Single hybrid motif 32
CoA-dependent acyltransferases ACP-like 33
PYP-like sensor domain (PAS domain) EAL domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
PDZ domain-like PDZ domain-like 32
Nucleotidyltransferase ACT-like 32
CheY-like PYP-like sensor domain (PAS domain) 33
Aconitase iron-sulfur domain LeuD/IlvD-like 33
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 31
Calcium ATPase, transmembrane domain M HAD-like 33
cAMP-binding domain-like "Winged helix" DNA-binding domain 31
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
Translation proteins EF-G C-terminal domain-like 33
Cytochrome c Cytochrome c 33
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 32
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
PLP-binding barrel Alanine racemase C-terminal domain-like 32
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 33
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Thioredoxin-like Thioredoxin-like 33
Nucleic acid-binding proteins RuvA domain 2-like 33
HD-domain/PDEase-like Nucleotidyltransferase 32
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Translation proteins SH3-like domain Nucleic acid-binding proteins 32
HD-domain/PDEase-like ACT-like 32
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Trypsin-like serine proteases PDZ domain-like 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Glutathione synthetase ATP-binding domain-like Single hybrid motif 32
Histidine-containing phosphotransfer domain, HPT domain Histidine-containing phosphotransfer domain, HPT domain 22
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 22
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
ACP-like alpha/beta-Hydrolases 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 21
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 22
RmlC-like cupins RmlC-like cupins 21
TGS-like ACT-like 21
HD-domain/PDEase-like TGS-like 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 22
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
HAMP domain-like CheY-like 22
HMA, heavy metal-associated domain HAD-like 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 22
OMPA-like TSP type-3 repeat 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
Single hybrid motif CoA-dependent acyltransferases 22
MetI-like MetI-like 21
cAMP-binding domain-like Rhodanese/Cell cycle control phosphatase 21
Histidine-containing phosphotransfer domain, HPT domain CheY-like 22
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 22
TPR-like TPR-like 22
OMPA-like OmpA-like 21
TrkA C-terminal domain-like TrkA C-terminal domain-like 22
P-loop containing nucleoside triphosphate hydrolases MOP-like 21
Acetyl-CoA synthetase-like alpha/beta-Hydrolases 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 21
GAF domain-like Nucleotide cyclase 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
ClpP/crotonase ClpP/crotonase 21
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
CoA-dependent acyltransferases alpha/beta-Hydrolases 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
ISP domain Bet v1-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
TSP type-3 repeat OmpA-like 21
Nucleotidyltransferase TGS-like 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
PUA domain-like Ribosomal protein S5 domain 2-like 22
Cupredoxins Cupredoxins 21
TSP type-3 repeat TSP type-3 repeat 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 22
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 21
HlyD-like secretion proteins HlyD-like secretion proteins 21
Aldolase post-HMGL domain-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Periplasmic binding protein-like II Lysozyme-like 22
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 21
PDZ domain-like ClpP/crotonase 21
GreA transcript cleavage protein, N-terminal domain FKBP-like 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 22
cAMP-binding domain-like cAMP-binding domain-like 21
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
CheY-like Nucleotide cyclase 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 11
Nucleic acid-binding proteins PheT/TilS domain 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
MesJ substrate recognition domain-like PheT/TilS domain 11
Flavoproteins Riboflavin synthase domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Barwin-like endoglucanases Sporulation related repeat 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Ribonuclease H-like Nucleic acid-binding proteins 11
TGS-like Class II aaRS and biotin synthetases 11
PIN domain-like Ribonuclease H-like 11
HMA, heavy metal-associated domain Cation efflux protein transmembrane domain-like 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
"Winged helix" DNA-binding domain GAF domain-like 11
PurS-like PurM C-terminal domain-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
TerB-like Chaperone J-domain 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Ferritin-like HAD-like 11
PUA domain-like Nucleotidylyl transferase 11
Nucleotidyltransferase Nucleotidyltransferase 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Putative DNA-binding domain Initiation factor IF2/eIF5b, domain 3 11
Nucleic acid-binding proteins BRCT domain 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Rad51 N-terminal domain-like Rad51 N-terminal domain-like 11
Peptide methionine sulfoxide reductase Mss4-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Translation proteins PRC-barrel domain 11
Ribokinase-like Nucleotidylyl transferase 11
Nucleotidylyl transferase Riboflavin kinase-like 11
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
DNA primase core DNA primase DnaG, C-terminal domain 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Zinc beta-ribbon Zinc beta-ribbon 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Histidine-containing phosphotransfer domain, HPT domain CheW-like 11
PPK N-terminal domain-like PHP14-like 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
Periplasmic binding protein-like II Periplasmic binding protein-like II 11
YjeF N-terminal domain-like Ribokinase-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Methionine synthase domain Methionine synthase activation domain-like 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
PHP domain-like Nucleic acid-binding proteins 11
HesB-like domain Fe-S cluster assembly (FSCA) domain-like 11
Nudix Nudix 11
Acyl-CoA N-acyltransferases (Nat) Carbon-nitrogen hydrolase 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Cyclophilin-like Single hybrid motif 11
Lysozyme-like PGBD-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
DNA clamp DNA clamp 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
FAD/NAD(P)-binding domain PurM N-terminal domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like EPT/RTPC-like 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Chorismate mutase II ACT-like 11
Nudix Thiamin phosphate synthase 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
Translation proteins ThrRS/AlaRS common domain 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
UROD/MetE-like UROD/MetE-like 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Zinc beta-ribbon DNA primase core 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Putative DNA-binding domain Translation proteins 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Homodimeric domain of signal transducing histidine kinase Histidine-containing phosphotransfer domain, HPT domain 11
KorB DNA-binding domain-like C-terminal domain of transcriptional repressors 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
PurS-like PurM N-terminal domain-like 11
Globin-like Riboflavin synthase domain-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
HAMP domain-like GAF domain-like 11
Homeodomain-like Homeodomain-like 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
MgtE N-terminal domain-like CBS-domain pair 11
FKBP-like FKBP-like 11
alpha/beta-Hydrolases NAD(P)-binding Rossmann-fold domains 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 11
vWA-like Quinoprotein alcohol dehydrogenase-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Lysozyme-like LysM domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
L30e-like alpha/beta knot 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
CBS-domain pair MgtE membrane domain-like 11
GroES-like GroES-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
TGS-like Class II aaRS ABD-related 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
HAMP domain-like Nucleotide cyclase 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
TGS-like ThrRS/AlaRS common domain 11
CheY-like EAL domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
Rubredoxin-like Rubredoxin-like 11
Cyclophilin-like Cyclophilin-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
PP2C-like Protein kinase-like (PK-like) 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Pili subunits GspK insert domain-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Tex N-terminal region-like RuvA domain 2-like 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
DsbC/DsbG N-terminal domain-like Thioredoxin-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Periplasmic binding protein-like II ACT-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
HRDC-like HRDC-like 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Ribonuclease H-like HRDC-like 11
PYP-like sensor domain (PAS domain) PilZ domain-like 11
PreATP-grasp domain PreATP-grasp domain 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
PurS-like Class I glutamine amidotransferase-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
PHP14-like Phospholipase D/nuclease 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Nucleic acid-binding proteins GAD domain-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
PapD-like Periplasmic chaperone C-domain 11
Macro domain-like Zn-dependent exopeptidases 11
Bacterial muramidases Lysozyme-like 11
DNA-glycosylase Nudix 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
Metalloproteases ("zincins"), catalytic domain PDZ domain-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Ferritin-like Calcium ATPase, transduction domain A 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Aldolase Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
GAF domain-like Homodimeric domain of signal transducing histidine kinase 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Chorismate mutase II Periplasmic binding protein-like II 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
MFS general substrate transporter MFS general substrate transporter 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Ribosomal protein L6 Ribosomal protein L6 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Carbamate kinase-like PUA domain-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Ribonuclease H-like DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
GAF domain-like CheY-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PurS-like FGAM synthase PurL, linker domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
Trigger factor ribosome-binding domain FKBP-like 11
cAMP-binding domain-like CBS-domain pair 11
Class II aaRS and biotin synthetases GAD domain-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Adenine nucleotide alpha hydrolases-like MesJ substrate recognition domain-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
ParB/Sulfiredoxin C-terminal domain of transcriptional repressors 11
GroEL equatorial domain-like GroEL apical domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Band 7/SPFH domain Band 7/SPFH domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RuvA domain 2-like RuvA domain 2-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
ACT-like HAD-like 11
Class I glutamine amidotransferase-like Homeodomain-like 11
GAF domain-like PYP-like sensor domain (PAS domain) 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
LysM domain LysM domain 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
post-HMGL domain-like Single hybrid motif 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
CarD-like TRCF domain-like 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Zn-dependent exopeptidases LysM domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Pseudouridine synthase PUA domain-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
PH0987 N-terminal domain-like Single hybrid motif 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Cupredoxins Cytochrome c 11
RuvA domain 2-like BRCT domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
PIN domain-like DNA/RNA polymerases 11
Class II aaRS and biotin synthetases Translation proteins 11
Rudiment single hybrid motif Cyclophilin-like 11
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 11
ACT-like Formyltransferase 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Carbamate kinase-like ACT-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Sporulation related repeat 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
PreATP-grasp domain Cyclophilin-like 11
Single hybrid motif Single hybrid motif 11
RNase III domain-like dsRNA-binding domain-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Thioredoxin-like FAD/NAD(P)-binding domain 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
NAD(P)-binding Rossmann-fold domains EPT/RTPC-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Nucleotidylyl transferase tRNA-binding arm 11
(Trans)glycosidases Glycoside hydrolase/deacetylase 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
YajQ-like YajQ-like 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
GIY-YIG endonuclease RuvA domain 2-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
GAF domain-like HD-domain/PDEase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Translation proteins Translation proteins 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
Zinc beta-ribbon DNA primase DnaG, C-terminal domain 11
GAF domain-like Phosphohistidine domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
GroEL-intermediate domain like GroEL apical domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
HCP-like HCP-like 11
Inosine monophosphate dehydrogenase (IMPDH) Inosine monophosphate dehydrogenase (IMPDH) 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
DNA methylase specificity domain DNA methylase specificity domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
CheW-like CheY-like 11
Tex N-terminal region-like Ribonuclease H-like 11
PUA domain-like alpha/beta knot 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Hsp33 domain HSP33 redox switch-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
NTF2-like Sec-C motif 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Formyltransferase FMT C-terminal domain-like 11
CheY-like PilZ domain-like 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Cyclophilin-like PH0987 N-terminal domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Globin-like Nucleotide cyclase 11
ACP-like ACP-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
FAD/NAD(P)-binding domain PurM C-terminal domain-like 11
Regulatory protein AraC Homeodomain-like 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
YrdC/RibB RibA-like 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11

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