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Domain combination pairs in Methylobacterium sp. 4-46

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

798 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 7545
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 591
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 4736
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 4532
Homodimeric domain of signal transducing histidine kinase CheY-like 4532
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 4317
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 3936
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 3830
PYP-like sensor domain (PAS domain) CheY-like 3023
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 263
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 246
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 241
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 234
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 237
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 225
CheY-like C-terminal effector domain of the bipartite response regulators 213
GroES-like NAD(P)-binding Rossmann-fold domains 205
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 192
Thioredoxin-like GST C-terminal domain-like 191
cAMP-binding domain-like "Winged helix" DNA-binding domain 193
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 186
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 176
Nucleotide cyclase EAL domain-like 176
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 165
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 165
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 165
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 165
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 165
PYP-like sensor domain (PAS domain) GAF domain-like 1615
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 152
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1515
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 154
Homeodomain-like Ribonuclease H-like 152
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 143
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 141
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 144
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 137
GAF domain-like Homodimeric domain of signal transducing histidine kinase 1313
CheY-like CheY-like 1310
P-loop containing nucleoside triphosphate hydrolases MOP-like 131
GAF domain-like CheY-like 1212
Thiolase-like Thiolase-like 123
PYP-like sensor domain (PAS domain) Nucleotide cyclase 126
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 114
PYP-like sensor domain (PAS domain) EAL domain-like 104
(Trans)glycosidases Glycosyl hydrolase domain 105
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 103
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 105
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 103
P-loop containing nucleoside triphosphate hydrolases Translation proteins 97
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 95
Homeodomain-like Homeodomain-like 95
Enolase N-terminal domain-like Enolase C-terminal domain-like 91
Actin-like ATPase domain Actin-like ATPase domain 93
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 94
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 85
Lysozyme-like beta-lactamase/transpeptidase-like 84
TPR-like TPR-like 74
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 71
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 77
beta-Roll beta-Roll 76
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 71
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 71
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 74
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 72
PYP-like sensor domain (PAS domain) Methyl-accepting chemotaxis protein (MCP) signaling domain 74
CheY-like P-loop containing nucleoside triphosphate hydrolases 72
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 71
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 65
lambda repressor-like DNA-binding domains RmlC-like cupins 61
E set domains (Trans)glycosidases 63
HAD-like Calcium ATPase, transmembrane domain M 66
Calcium ATPase, transduction domain A HAD-like 66
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 66
Trypsin-like serine proteases PDZ domain-like 62
"Winged helix" DNA-binding domain GAF domain-like 61
Histidine-containing phosphotransfer domain, HPT domain CheY-like 66
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 66
CheY-like Nucleotide cyclase 65
CheY-like Homeodomain-like 61
Nucleic acid-binding proteins Nucleic acid-binding proteins 65
PreATP-grasp domain Rudiment single hybrid motif 52
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 52
Single hybrid motif CoA-dependent acyltransferases 52
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 54
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 54
MoeA N-terminal region -like MoeA C-terminal domain-like 53
E set domains Glycosyl hydrolase domain 52
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 52
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 53
"Winged helix" DNA-binding domain Chorismate lyase-like 52
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52
Nucleotide cyclase TPR-like 52
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 54
Succinyl-CoA synthetase domains Glutathione synthetase ATP-binding domain-like 54
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 54
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 54
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 53
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 51
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 53
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 54
Molybdenum cofactor-binding domain Molybdenum cofactor-binding domain 51
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 51
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 51
GAF domain-like Nucleotide cyclase 43
Ferredoxin reductase-like, C-terminal NADP-linked domain 2Fe-2S ferredoxin-like 43
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 41
TPR-like Caspase-like 44
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 43
RmlC-like cupins Homeodomain-like 43
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 41
Translation proteins EF-G C-terminal domain-like 43
HlyD-like secretion proteins HlyD-like secretion proteins 42
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 43
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 43
ACP-like Acetyl-CoA synthetase-like 44
Triger factor/SurA peptide-binding domain-like FKBP-like 43
PGBD-like L,D-transpeptidase catalytic domain-like 42
Riboflavin synthase domain-like 2Fe-2S ferredoxin-like 43
PurM N-terminal domain-like PurM C-terminal domain-like 42
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 41
Alpha-L RNA-binding motif Pseudouridine synthase 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 43
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 42
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 43
Resolvase-like Homeodomain-like 41
Cytochrome c Cytochrome c 42
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 44
TPR-like UDP-Glycosyltransferase/glycogen phosphorylase 42
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 41
GAF domain-like GAF domain-like 44
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 33
MetI-like MetI-like 33
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 33
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
PK beta-barrel domain-like PK C-terminal domain-like 31
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 33
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 33
ACT-like ACT-like 33
GroEL equatorial domain-like GroEL-intermediate domain like 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 31
GroEL-intermediate domain like GroEL apical domain-like 31
Histidine-containing phosphotransfer domain, HPT domain CheW-like 33
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 32
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 33
FabD/lysophospholipase-like ACP-like 33
GroEL equatorial domain-like GroEL apical domain-like 31
Galactose mutarotase-like E set domains 31
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 33
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
PDZ domain-like PDZ domain-like 31
NAD(P)-binding Rossmann-fold domains Glutathione synthetase ATP-binding domain-like 33
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 31
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
ClpP/crotonase ClpP/crotonase 31
Regulatory protein AraC Homeodomain-like 31
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 33
Nucleic acid-binding proteins RuvA domain 2-like 33
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Thiolase-like NAD(P)-binding Rossmann-fold domains 33
"Winged helix" DNA-binding domain PLP-dependent transferases 31
NAD(P)-binding Rossmann-fold domains ACP-like 33
CheY-like Methylesterase CheB, C-terminal domain 32
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 31
CheY-like HD-domain/PDEase-like 31
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Phospholipase D/nuclease Phospholipase D/nuclease 33
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 33
(Trans)glycosidases (Trans)glycosidases 33
Thiolase-like FabD/lysophospholipase-like 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 33
PLP-binding barrel Alanine racemase C-terminal domain-like 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 33
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 33
alpha/beta-Hydrolases alpha/beta-Hydrolases 31
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 31
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 33
Lysozyme-like PGBD-like 31
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 33
NAD(P)-binding Rossmann-fold domains ACT-like 33
Phase 1 flagellin Phase 1 flagellin 31
Formyltransferase FMT C-terminal domain-like 31
Class I glutamine amidotransferase-like Homeodomain-like 31
Thiolase-like ACP-like 33
Methyl-accepting chemotaxis protein (MCP) signaling domain Methyl-accepting chemotaxis protein (MCP) signaling domain 33
CBS-domain pair FAD-binding/transporter-associated domain-like 31
Probable ACP-binding domain of malonyl-CoA ACP transacylase NAD(P)-binding Rossmann-fold domains 33
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 31
Nqo1 middle domain-like Nqo1C-terminal domain-like 33
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
Galactose oxidase, central domain E set domains 22
PYP-like sensor domain (PAS domain) C-terminal effector domain of the bipartite response regulators 22
Metalloproteases ("zincins"), catalytic domain beta-Roll 22
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
Acetyl-CoA synthetase-like Glycerol-3-phosphate (1)-acyltransferase 22
HMA, heavy metal-associated domain HAD-like 22
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 21
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Methyl-accepting chemotaxis protein (MCP) signaling domain PilZ domain-like 22
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 22
Single hybrid motif FAD/NAD(P)-binding domain 22
FliG FliG 21
Thioredoxin-like Nqo1C-terminal domain-like 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 22
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 21
ParB/Sulfiredoxin KorB DNA-binding domain-like 21
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 22
FabD/lysophospholipase-like GroES-like 22
CheW-like CheY-like 22
Lysozyme-like Staphylococcal nuclease 21
ACP-like ACP-like 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Flavoproteins Riboflavin synthase domain-like 21
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Trimeric LpxA-like enzymes Trimeric LpxA-like enzymes 22
HCP-like HCP-like 22
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 22
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 21
Methyl-accepting chemotaxis protein (MCP) signaling domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Methyl-accepting chemotaxis protein (MCP) signaling domain CheY-like 22
Globin-like Riboflavin synthase domain-like 21
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 22
L30e-like alpha/beta knot 21
Thiolase-like GroES-like 22
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
ISP domain Bet v1-like 21
Nucleotide-diphospho-sugar transferases UDP-Glycosyltransferase/glycogen phosphorylase 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 21
HAMP domain-like Nucleotide cyclase 22
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 22
Thioredoxin-like Nqo1 middle domain-like 22
CheC-like Surface presentation of antigens (SPOA) 22
CarD-like TRCF domain-like 22
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
4Fe-4S ferredoxins ADC-like 22
beta-lactamase/transpeptidase-like Staphylococcal nuclease 21
Methyl-accepting chemotaxis protein (MCP) signaling domain GAF domain-like 22
P-loop containing nucleoside triphosphate hydrolases MetI-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Thioredoxin-like Nqo1 FMN-binding domain-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Rudiment single hybrid motif Single hybrid motif 21
PreATP-grasp domain Single hybrid motif 21
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
TrkA C-terminal domain-like TrkA C-terminal domain-like 21
Nucleotidyltransferase ACT-like 22
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 22
Glutathione synthetase ATP-binding domain-like Single hybrid motif 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Methyl-accepting chemotaxis protein (MCP) signaling domain Homodimeric domain of signal transducing histidine kinase 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
PGBD-like Trypsin-like serine proteases 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 22
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 22
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 21
CheW-like CheW-like 22
P-loop containing nucleoside triphosphate hydrolases CarD-like 22
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 22
Cupredoxins Cytochrome c 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 21
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 21
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
P-loop containing nucleoside triphosphate hydrolases Protein kinase-like (PK-like) 22
Metallo-hydrolase/oxidoreductase SCP-like 21
Cupredoxins Cupredoxins 22
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
Folate-binding domain Aminomethyltransferase beta-barrel domain 22
Globin-like Methyl-accepting chemotaxis protein (MCP) signaling domain 22
Metallo-dependent phosphatases beta-Roll 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
GroES-like ACP-like 22
Oxidoreductase molybdopterin-binding domain E set domains 21
RuvA domain 2-like P-loop containing nucleoside triphosphate hydrolases 21
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 21
Probable ACP-binding domain of malonyl-CoA ACP transacylase Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
C-terminal effector domain of the bipartite response regulators TPR-like 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 22
Metalloproteases ("zincins"), catalytic domain Integrin alpha N-terminal domain 22
Aconitase iron-sulfur domain LeuD/IlvD-like 21
Urease metallochaperone UreE, N-terminal domain Urease metallochaperone UreE, C-terminal domain 22
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 21
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 22
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 22
PDZ domain-like ClpP/crotonase 22
Homodimeric domain of signal transducing histidine kinase CheW-like 22
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 21
Clc chloride channel CBS-domain pair 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Glutathione synthetase ATP-binding domain-like Acyl-CoA N-acyltransferases (Nat) 22
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 21
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 21
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 22
FabD/lysophospholipase-like FabD/lysophospholipase-like 22
Translation proteins Ribosomal protein S5 domain 2-like 21
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 22
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 21
GAF domain-like EAL domain-like 21
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 21
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 21
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Tricorn protease N-terminal domain ClpP/crotonase 11
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
RuvA domain 2-like JAB1/MPN domain 11
PIN domain-like DNA/RNA polymerases 11
Nucleotidyltransferase substrate binding subunit/domain Poly A polymerase C-terminal region-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
OMPA-like OMPT-like 11
GAF domain-like Homeodomain-like 11
HD-domain/PDEase-like TGS-like 11
NAD(P)-binding Rossmann-fold domains Tetrapyrrole methylase 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Tex N-terminal region-like Ribonuclease H-like 11
Ribonuclease H-like DNA/RNA polymerases 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Concanavalin A-like lectins/glucanases beta-Roll 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
N-acetylmuramoyl-L-alanine amidase-like PGBD-like 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Homeodomain-like 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
Dihydropteroate synthetase-like Methionine synthase domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
GAF domain-like Phosphoenolpyruvate/pyruvate domain 11
Translation proteins Periplasmic binding protein-like II 11
UDP-Glycosyltransferase/glycogen phosphorylase Glycoside hydrolase/deacetylase 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
TGS-like ThrRS/AlaRS common domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
PHP domain-like AF1531-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
Methylesterase CheB, C-terminal domain Tropomyosin 11
GAF domain-like Phosphohistidine domain 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
OMPA-like OMPA-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
P-loop containing nucleoside triphosphate hydrolases vWA-like 11
Fumarate reductase respiratory complex transmembrane subunits Nucleotide cyclase 11
Trigger factor ribosome-binding domain FKBP-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Galactose oxidase, central domain Quinoprotein alcohol dehydrogenase-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
GAF domain-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
HAMP domain-like GAF domain-like 11
N-terminal domain of bifunctional PutA protein FAD-linked oxidoreductase 11
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 11
Metallo-hydrolase/oxidoreductase GAF domain-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
Folate-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Urease, gamma-subunit Urease, beta-subunit 11
Acid phosphatase/Vanadium-dependent haloperoxidase Autotransporter 11
Nucleic acid-binding proteins PheT/TilS domain 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
HD-domain/PDEase-like ACT-like 11
MoeA N-terminal region -like Periplasmic binding protein-like II 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
YrdC/RibB RibA-like 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
FAD-linked oxidoreductase ALDH-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Ricin B-like lectins E set domains 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
MalF N-terminal region-like MetI-like 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
HAMP domain-like EAL domain-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors C-terminal effector domain of the bipartite response regulators 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Calcium-dependent phosphotriesterase Autotransporter 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors CheY-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 11
ACP-like Glycerol-3-phosphate (1)-acyltransferase 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
CBS-domain pair MgtE membrane domain-like 11
Metallo-hydrolase/oxidoreductase CheY-like 11
ABC transporter transmembrane region ABC transporter transmembrane region 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
Ricin B-like lectins Ricin B-like lectins 11
Nucleic acid-binding proteins GAD domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Ribosomal protein L6 Ribosomal protein L6 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
dUTPase-like dUTPase-like 11
Ferritin-like Calcium ATPase, transmembrane domain M 11
TGS-like ACT-like 11
RuBisCO, large subunit, small (N-terminal) domain RuBisCo, C-terminal domain 11
OmpA-like OmpA-like 11
alpha/beta-Hydrolases ACP-like 11
DNA breaking-rejoining enzymes DNA breaking-rejoining enzymes 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Nucleotide-diphospho-sugar transferases S-adenosyl-L-methionine-dependent methyltransferases 11
YlxR-like L30e-like 11
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain beta-Roll 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, peptide-binding domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
RuvA domain 2-like BRCT domain 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
alpha/beta-Hydrolases AhpD-like 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Class II aaRS and biotin synthetases Translation proteins 11
TGS-like Class II aaRS ABD-related 11
ADC-like Cdc48 domain 2-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Translation proteins "Winged helix" DNA-binding domain 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
Radical SAM enzymes Nitrogenase accessory factor-like 11
Serine metabolism enzymes domain ACT-like 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Nucleotidyltransferase Nucleotidyltransferase 11
Translation proteins Translation proteins 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
PreATP-grasp domain PreATP-grasp domain 11
MoeA C-terminal domain-like Periplasmic binding protein-like II 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain "Winged helix" DNA-binding domain 11
Nucleotide-binding domain Nucleotide-binding domain 11
RuvA domain 2-like RuvA domain 2-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
Ribonuclease H-like RuvA domain 2-like 11
alpha/beta-Hydrolases Acetyl-CoA synthetase-like 11
L domain-like Protein kinase-like (PK-like) 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
HAMP domain-like PYP-like sensor domain (PAS domain) 11
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
alpha-helical ferredoxin SCP-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
S-adenosyl-L-methionine-dependent methyltransferases PYP-like sensor domain (PAS domain) 11
cAMP-binding domain-like CBS-domain pair 11
PIN domain-like Ribonuclease H-like 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Acetyl-CoA synthetase-like Trimeric LpxA-like enzymes 11
DinB/YfiT-like putative metalloenzymes C-type lectin-like 11
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
Zinc beta-ribbon DNA primase core 11
Nucleotidyltransferase TGS-like 11
GIY-YIG endonuclease RuvA domain 2-like 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Tropomyosin ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
AF0104/ALDC/Ptd012-like AF0104/ALDC/Ptd012-like 11
WD40 repeat-like Cytochrome c 11
Ferritin-like Calcium ATPase, transduction domain A 11
beta-lactamase/transpeptidase-like Sporulation related repeat 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
NAD(P)-binding Rossmann-fold domains Acyl-CoA N-acyltransferases (Nat) 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
PH0987 N-terminal domain-like Cyclophilin-like 11
FAD/NAD(P)-binding domain Folate-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase domain 11
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Nudix "Winged helix" DNA-binding domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
3-carboxy-cis,cis-mucoante lactonizing enzyme beta-Roll 11
Caspase-like HCP-like 11
Sigma2 domain of RNA polymerase sigma factors NTF2-like 11
Nucleic acid-binding proteins BRCT domain 11
TGS-like Class II aaRS and biotin synthetases 11
NE0471 N-terminal domain-like lambda repressor-like DNA-binding domains 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
TolB, N-terminal domain Tricorn protease N-terminal domain 11
E set domains Quinoprotein alcohol dehydrogenase-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
2Fe-2S ferredoxin-like Bet v1-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases ACT-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
TerB-like Chaperone J-domain 11
Integrin alpha N-terminal domain Integrin alpha N-terminal domain 11
ACP-like Trimeric LpxA-like enzymes 11
MFS general substrate transporter Acetyl-CoA synthetase-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
Nucleotidylyl transferase tRNA-binding arm 11
Hsp33 domain HSP33 redox switch-like 11
3-carboxy-cis,cis-mucoante lactonizing enzyme DNase I-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
Homodimeric domain of signal transducing histidine kinase Nucleotide cyclase 11
Acetamidase/Formamidase-like Acetamidase/Formamidase-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Tricorn protease N-terminal domain DPP6 N-terminal domain-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PRTase-like EreA/ChaN-like 11
DPP6 N-terminal domain-like PDZ domain-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Methylesterase CheB, C-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
PilZ domain-like PilZ domain-like 11
N-terminal domain of bifunctional PutA protein ALDH-like 11
PPK N-terminal domain-like PHP14-like 11
TPR-like HCP-like 11
Carbamate kinase-like PUA domain-like 11
Folate-binding domain TrmE connector domain 11
Homocysteine S-methyltransferase Methionine synthase domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
YjeF N-terminal domain-like Ribokinase-like 11
MFS general substrate transporter Glycerol-3-phosphate (1)-acyltransferase 11
FabD/lysophospholipase-like S-adenosyl-L-methionine-dependent methyltransferases 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
Nucleotide cyclase SMAD/FHA domain 11
DPP6 N-terminal domain-like ClpP/crotonase 11
GroES-like GroES-like 11
Tricorn protease N-terminal domain PDZ domain-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
P-loop containing nucleoside triphosphate hydrolases Periplasmic binding protein-like II 11
Single hybrid motif TK C-terminal domain-like 11
Transmembrane di-heme cytochromes CBD9-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
RNase III domain-like dsRNA-binding domain-like 11
beta-Roll Integrin alpha N-terminal domain 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
HAMP domain-like Histidine-containing phosphotransfer domain, HPT domain 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
ADC-like P-loop containing nucleoside triphosphate hydrolases 11
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Periplasmic binding protein-like II 11
Poly A polymerase C-terminal region-like ACT-like 11
Glycoside hydrolase/deacetylase UraD-Like 11
DAK1/DegV-like DhaL-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Formylmethanofuran:tetrahydromethanopterin formyltransferase Formylmethanofuran:tetrahydromethanopterin formyltransferase 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
NAD(P)-binding Rossmann-fold domains MurD-like peptide ligases, catalytic domain 11
HRDC-like HRDC-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
PYP-like sensor domain (PAS domain) lambda repressor-like DNA-binding domains 11
CO dehydrogenase ISP C-domain like Bet v1-like 11
Thioredoxin-like TPR-like 11
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) Thioredoxin-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
Nucleotide cyclase TolB, N-terminal domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Zn-dependent exopeptidases "Winged helix" DNA-binding domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Bacterial muramidases Lysozyme-like 11
DNase I-like beta-Roll 11
Carbamate kinase-like ACT-like 11
DeoB insert domain-like Alkaline phosphatase-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Macro domain-like Zn-dependent exopeptidases 11
Fumarate reductase respiratory complex transmembrane subunits 2Fe-2S ferredoxin-like 11
S-adenosyl-L-methionine-dependent methyltransferases Tropomyosin 11
Soluble quinoprotein glucose dehydrogenase Cytochrome c 11
Tropomyosin PYP-like sensor domain (PAS domain) 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Caspase-like C-type lectin-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Actin-like ATPase domain HD-domain/PDEase-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Nitrous oxide reductase, N-terminal domain Cupredoxins 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain P-loop containing nucleoside triphosphate hydrolases 11
Methylesterase CheB, C-terminal domain Chemotaxis receptor methyltransferase CheR, N-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Pectin lyase-like Autotransporter 11
FAD-linked reductases, C-terminal domain Folate-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors NTF2-like 11
Nucleotide-diphospho-sugar transferases IpsF-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
CoA-transferase family III (CaiB/BaiF) CoA-transferase family III (CaiB/BaiF) 11
Thioesterase/thiol ester dehydrase-isomerase Isocitrate/Isopropylmalate dehydrogenase-like 11
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
HAMP domain-like CheY-like 11
TPR-like Terpenoid cyclases/Protein prenyltransferases 11
Periplasmic binding protein-like II ACT-like 11
SIS domain CBS-domain pair 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
DNA clamp DNA clamp 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
PLP-dependent transferases PLP-dependent transferases 11
Creatinase/prolidase N-terminal domain Creatinase/prolidase N-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Methionine synthase domain Methionine synthase activation domain-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
Thiamin diphosphate-binding fold (THDP-binding) Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
2Fe-2S ferredoxin-like ADC-like 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
Homeodomain-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Single hybrid motif Thiamin diphosphate-binding fold (THDP-binding) 11
Metalloproteases ("zincins"), catalytic domain Hedgehog/intein (Hint) domain 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Molybdenum cofactor-binding domain Bet v1-like 11
Concanavalin A-like lectins/glucanases Metallo-dependent phosphatases 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
CO dehydrogenase molybdoprotein N-domain-like Bet v1-like 11
FMN-binding split barrel Riboflavin synthase domain-like 11
Glycosyl hydrolase domain Protein kinase-like (PK-like) 11
FMN-binding split barrel 2Fe-2S ferredoxin-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
MgtE N-terminal domain-like CBS-domain pair 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Ricin B-like lectins Galactose oxidase, central domain 11
PspA lactotransferrin-binding region OmpA-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Aldolase SIS domain 11
Photosystem II reaction centre subunit H, transmembrane region PRC-barrel domain 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
PheT/TilS domain Putative DNA-binding domain 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
S-adenosyl-L-methionine-dependent methyltransferases ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
HPr-like Phosphohistidine domain 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
Succinyl-CoA synthetase domains Acyl-CoA N-acyltransferases (Nat) 11
"Winged helix" DNA-binding domain SCP-like 11
Ribonuclease H-like HRDC-like 11
2Fe-2S ferredoxin-like Nucleotide cyclase 11
Radical SAM enzymes RuvA domain 2-like 11
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 11
FMN-binding split barrel Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Galactose oxidase, central domain Galactose oxidase, central domain 11
Tex N-terminal region-like RuvA domain 2-like 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
YebC-like PFL-like glycyl radical enzymes 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
PHP14-like Phospholipase D/nuclease 11
GAF domain-like C-terminal effector domain of the bipartite response regulators 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Translation proteins ThrRS/AlaRS common domain 11
"Winged helix" DNA-binding domain Bet v1-like 11
Methylesterase CheB, C-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
Ada DNA repair protein, N-terminal domain (N-Ada 10) Methylated DNA-protein cysteine methyltransferase domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Ferritin-like HAD-like 11
FAD-linked reductases, C-terminal domain Thioredoxin-like 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
FAD/NAD(P)-binding domain Thioredoxin-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Translation proteins PRC-barrel domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
Molybdenum cofactor biosynthesis proteins Periplasmic binding protein-like II 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
PUA domain-like alpha/beta knot 11
alpha/beta-Hydrolases Galactose-binding domain-like 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
beta-Roll Hedgehog/intein (Hint) domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
beta-Barrel protease inhibitors beta-Barrel protease inhibitors 11
beta-lactamase/transpeptidase-like Penicillin-binding protein associated domain 11
lambda repressor-like DNA-binding domains P-loop containing nucleoside triphosphate hydrolases 11
UraD-Like Transthyretin (synonym: prealbumin) 11
PYP-like sensor domain (PAS domain) Homeodomain-like 11
SufE/NifU Fe-S cluster assembly (FSCA) domain-like 11
Methylesterase CheB, C-terminal domain PYP-like sensor domain (PAS domain) 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Ribonuclease H-like Nucleic acid-binding proteins 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
DNA-glycosylase Nudix 11
Tetrapyrrole methylase S-adenosyl-L-methionine-dependent methyltransferases 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain PYP-like sensor domain (PAS domain) 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain TPR-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain Tropomyosin 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
LysM domain Duplicated hybrid motif 11

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