Domain combination pairs in Eucalyptus grandis v201

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

• For a list of unique full length architectures for this genome click here (can be slow).

Graph of adjacent domain pairs.

• Remove domain pairs for which there is already a structure in the PDB
• Remove domain pairs which occur in any other genomes (slow)
• Remove domain pairs which are not adjacent to each other
• Remove different strains from the list of genomes compared to

Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

1443 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
L domain-like	L domain-like	694	127
P-loop containing nucleoside triphosphate hydrolases	L domain-like	639	99
L domain-like	Protein kinase-like (PK-like)	636	44
L domain-like	RNI-like	390	108
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	338	68
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	308	14
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	306	65
GroES-like	NAD(P)-binding Rossmann-fold domains	206	8
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	204	41
Toll/Interleukin receptor TIR domain	L domain-like	198	46
RNI-like	Protein kinase-like (PK-like)	179	31
Toll/Interleukin receptor TIR domain	"Winged helix" DNA-binding domain	146	25
Thioredoxin-like	GST C-terminal domain-like	138	7
"Winged helix" DNA-binding domain	L domain-like	132	29
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	131	5
Cupredoxins	Cupredoxins	128	14
RNA-binding domain, RBD	RNA-binding domain, RBD	124	28
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	111	19
RNI-like	RNI-like	109	49
HAD-like	Calcium ATPase, transmembrane domain M	106	19
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	104	19
Calcium ATPase, transduction domain A	HAD-like	99	15
F-box domain	RNI-like	95	10
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	89	5
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	88	2
ABC transporter transmembrane region	ABC transporter transmembrane region	87	11
TPR-like	TPR-like	86	21
P-loop containing nucleoside triphosphate hydrolases	RNI-like	73	39
Actin-like ATPase domain	Actin-like ATPase domain	73	17
Calcium ATPase, transmembrane domain M	Metal cation-transporting ATPase, ATP-binding domain N	72	13
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	69	11
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	69	10
RING/U-box	ARM repeat	68	10
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	66	7
ARM repeat	ARM repeat	65	26
Periplasmic binding protein-like I	Periplasmic binding protein-like II	64	7
Thiolase-like	Thiolase-like	55	2
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	54	10
(Trans)glycosidases	Galactose-binding domain-like	54	11
Voltage-gated potassium channels	cAMP-binding domain-like	54	6
(Trans)glycosidases	Glycosyl hydrolase domain	53	10
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	53	6
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	51	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	48	7
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	48	7
Protein kinase-like (PK-like)	EF-hand	48	2
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	47	7
RING/U-box	RING/U-box	43	21
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	43	3
Barwin-like endoglucanases	PHL pollen allergen	43	2
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	40	4
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	40	14
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	38	7
TRAF domain-like	TRAF domain-like	37	4
Cyclin-like	Cyclin-like	37	7
GroES-like	GroES-like	36	5
Homeodomain-like	Homeodomain-like	36	11
ENTH/VHS domain	GAT-like domain	35	5
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	35	7
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	34	10
CCCH zinc finger	CCCH zinc finger	32	20
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	31	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	31	6
Galactose-binding domain-like	Galactose-binding domain-like	31	4
ACT-like	ACT-like	30	11
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	30	8
F-box domain	Galactose oxidase, central domain	30	3
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	29	14
Thioredoxin-like	Thioredoxin-like	29	16
WD40 repeat-like	WD40 repeat-like	29	15
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	29	7
Cullin repeat-like	Cullin homology domain	28	3
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	28	7
SNARE-like	SNARE fusion complex	28	3
Phospholipase D/nuclease	Phospholipase D/nuclease	28	12
Cullin homology domain	"Winged helix" DNA-binding domain	28	4
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	27	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	27	13
Galactose mutarotase-like	(Trans)glycosidases	26	5
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	26	5
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	26	3
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	26	4
Protein kinase-like (PK-like)	ARM repeat	26	13
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	25	1
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	25	5
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	25	6
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	25	5
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	24	4
Cullin repeat-like	"Winged helix" DNA-binding domain	24	2
DNA-binding domain	DNA-binding domain	24	4
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	24	8
YhbY-like	YhbY-like	24	8
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	24	3
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	23	10
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	23	11
WRKY DNA-binding domain	WRKY DNA-binding domain	23	2
Nucleic acid-binding proteins	Nucleic acid-binding proteins	22	16
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	22	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	22	2
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	22	4
Trypsin-like serine proteases	PDZ domain-like	22	5
Homeodomain-like	Bet v1-like	22	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	22	8
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	21	7
F-box domain	Kelch motif	21	3
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	21	11
Galactose mutarotase-like	Glycosyl hydrolase domain	21	2
Ankyrin repeat	Ankyrin repeat	21	5
PAZ domain	Ribonuclease H-like	21	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	21	3
RING/U-box	Nucleotide-diphospho-sugar transferases	21	3
DNA-binding pseudobarrel domain	CAD & PB1 domains	21	4
Bet v1-like	Bet v1-like	20	6
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	20	3
GroEL equatorial domain-like	GroEL-intermediate domain like	20	3
GroEL-intermediate domain like	GroEL apical domain-like	20	3
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	20	6
Ubiquitin-like	UBA-like	20	8
(Trans)glycosidases	Chitinase insertion domain	20	3
Mannose-binding lectins	Mannose-binding lectins	20	12
CHY zinc finger-like	Zinc hairpin stack	20	5
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	20	3
GroEL equatorial domain-like	GroEL apical domain-like	20	3
CHY zinc finger-like	RING/U-box	19	4
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	19	4
Zinc hairpin stack	RING/U-box	19	4
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	19	3
Clc chloride channel	CBS-domain pair	18	6
PK beta-barrel domain-like	PK C-terminal domain-like	18	2
Voltage-gated potassium channels	EF-hand	18	8
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	18	9
POZ domain	Skp1 dimerisation domain-like	18	4
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	18	3
vWA-like	RING/U-box	18	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	18	2
Protein kinase-like (PK-like)	RING/U-box	18	4
TPR-like	HCP-like	18	7
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	18	9
Toll/Interleukin receptor TIR domain	RNI-like	18	14
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	18	2
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	17	4
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	17	4
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	17	2
FYVE/PHD zinc finger	FYVE/PHD zinc finger	17	10
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	17	6
CCCH zinc finger	WD40 repeat-like	16	1
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	16	4
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	16	2
Cysteine-rich domain	Cysteine-rich domain	16	11
Translation proteins SH3-like domain	Nucleic acid-binding proteins	16	5
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	16	3
dsRNA-binding domain-like	dsRNA-binding domain-like	16	9
Voltage-gated potassium channels	Voltage-gated potassium channels	16	7
EF-G C-terminal domain-like	EF-G C-terminal domain-like	16	7
Subtilisin-like	PA domain	16	4
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	16	4
UROD/MetE-like	UROD/MetE-like	16	2
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	16	3
Translation proteins	EF-G C-terminal domain-like	16	7
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	16	6
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	16	7
cAMP-binding domain-like	Ankyrin repeat	15	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	15	5
Voltage-gated potassium channels	Ankyrin repeat	15	2
CCCH zinc finger	RNA-binding domain, RBD	15	4
NAD(P)-binding Rossmann-fold domains	Aldolase	15	2
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	15	5
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	15	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	15	5
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	15	3
Ubiquitin-like	Ubiquitin-like	15	6
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	15	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	15	5
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	15	9
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	15	2
NAD(P)-binding Rossmann-fold domains	ACT-like	14	4
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	14	4
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	14	5
Plant lectins/antimicrobial peptides	Lysozyme-like	14	1
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	14	5
ENT-like	Tudor/PWWP/MBT	14	2
ARM repeat	WD40 repeat-like	14	10
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	14	5
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	14	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	14	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	14	5
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	14	3
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	14	5
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	14	1
P-loop containing nucleoside triphosphate hydrolases	ARM repeat	13	6
NTF2-like	RNA-binding domain, RBD	13	2
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	13	6
FKBP-like	TPR-like	13	3
PH domain-like	FYVE/PHD zinc finger	13	2
FAS1 domain	FAS1 domain	13	4
Chromo domain-like	Chromo domain-like	13	5
EF-hand	EF-hand	13	5
HCP-like	HCP-like	13	7
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	13	6
Growth factor receptor domain	Protein kinase-like (PK-like)	13	2
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	13	7
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	12	4
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	12	7
Single hybrid motif	CoA-dependent acyltransferases	12	5
EF-hand	PLC-like phosphodiesterases	12	3
"Winged helix" DNA-binding domain	RNI-like	12	10
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	12	6
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	12	2
Galactose-binding domain-like	Galactose mutarotase-like	12	3
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	12	5
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	12	3
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	12	4
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	12	3
Serine metabolism enzymes domain	ACT-like	12	3
RCC1/BLIP-II	RCC1/BLIP-II	12	3
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	12	2
Acid proteases	Saposin	12	3
CBS-domain pair	CBS-domain pair	12	8
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	12	6
POZ domain	TRAF domain-like	12	3
PreATP-grasp domain	Rudiment single hybrid motif	12	5
CAD & PB1 domains	Protein kinase-like (PK-like)	12	2
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	12	2
EGF/Laminin	Protein kinase-like (PK-like)	12	4
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	11	5
Starch-binding domain-like	Galactose-binding domain-like	11	2
RING/U-box	WD40 repeat-like	11	8
BRCT domain	BRCT domain	11	5
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	11	8
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	11	6
Galactose mutarotase-like	Starch-binding domain-like	11	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	11	5
Tricorn protease domain 2	alpha/beta-Hydrolases	11	2
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	11	2
Ankyrin repeat	POZ domain	11	5
Homeodomain-like	"Winged helix" DNA-binding domain	11	3
ACT-like	Protein kinase-like (PK-like)	11	1
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	11	6
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	11	8
TRAF domain-like	Cysteine proteinases	11	2
E set domains	(Trans)glycosidases	10	6
Protease propeptides/inhibitors	Subtilisin-like	10	3
Cysteine proteinases	Sec-C motif	10	5
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	10	5
Protein kinase-like (PK-like)	TPR-like	10	3
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	10	8
LysM domain	Protein kinase-like (PK-like)	10	3
PA domain	RING/U-box	10	2
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	10	4
Amine oxidase N-terminal region	Amine oxidase N-terminal region	10	4
HMA, heavy metal-associated domain	HAD-like	10	7
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	10	7
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	10	4
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	10	4
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	10	4
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	10	6
MFS general substrate transporter	MFS general substrate transporter	10	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	9	3
FYVE/PHD zinc finger	RING/U-box	9	6
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	9	2
Actin depolymerizing proteins	Actin depolymerizing proteins	9	5
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	9	4
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	9	5
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	9	2
(Trans)glycosidases	Ricin B-like lectins	9	3
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	9	3
CheY-like	Homeodomain-like	9	2
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	9	2
HIT/MYND zinc finger-like	SET domain	9	4
TPR-like	RING/U-box	9	4
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	9	2
(Trans)glycosidases	Protein kinase-like (PK-like)	9	3
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	9	3
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	9	7
PGBD-like	Metalloproteases ("zincins"), catalytic domain	9	2
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	9	3
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	3
FKBP-like	FKBP-like	9	2
RING/U-box	TRAF domain-like	8	2
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	8	4
Zn-finger domain of Sec23/24	vWA-like	8	4
Actin depolymerizing proteins	VHP, Villin headpiece domain	8	4
FYVE/PHD zinc finger	SET domain	8	5
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	8	2
UBA-like	UBA-like	8	6
ARM repeat	Hect, E3 ligase catalytic domain	8	3
L9 N-domain-like	Ribonuclease H-like	8	1
F-box domain	Tubby C-terminal domain-like	8	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	8	3
WW domain	WW domain	8	5
vWA-like	Helical domain of Sec23/24	8	4
Translation proteins	Ribosomal protein S5 domain 2-like	8	4
PH domain-like	Oxysterol-binding protein-like	8	1
P-loop containing nucleoside triphosphate hydrolases	Mannose-binding lectins	8	4
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	8	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	8	5
Amine oxidase N-terminal region	Amine oxidase catalytic domain	8	4
Protein kinase-like (PK-like)	WD40 repeat-like	8	5
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	8	2
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	8	4
E set domains	Glycosyl hydrolase domain	8	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	8	2
Macro domain-like	CRAL/TRIO domain	8	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	8	6
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	8	4
vWA-like	beta-sandwich domain of Sec23/24	8	4
Periplasmic binding protein-like II	ACT-like	8	2
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	8	4
RNase III domain-like	RNase III domain-like	8	6
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	8	3
ADC-like	P-loop containing nucleoside triphosphate hydrolases	8	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	8	4
Kelch motif	Kelch motif	8	4
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	8	3
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	8	4
ADC-like	Cdc48 domain 2-like	8	3
EF-hand	Riboflavin synthase domain-like	8	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	8	2
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	8	2
Adenine nucleotide alpha hydrolases-like	RING/U-box	8	2
L domain-like	Outer arm dynein light chain 1	8	6
Cysteine proteinases	Granulin repeat	8	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	8	4
GST C-terminal domain-like	GST C-terminal domain-like	8	2
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	7	2
RNase III domain-like	dsRNA-binding domain-like	7	6
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	7	2
Translational machinery components	L30e-like	7	3
RING/U-box	Homeodomain-like	7	3
POZ domain	TAZ domain	7	2
beta-beta-alpha zinc fingers	Ribonuclease H-like	7	3
CheY-like	CheY-like	7	1
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
RING/U-box	RNA-binding domain, RBD	7	2
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	7	1
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	7	5
Ribosomal protein L6	Ribosomal protein L6	7	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	7	4
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	7	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	7	1
PDZ domain-like	ClpP/crotonase	7	1
ISP domain	Bet v1-like	7	3
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	7	4
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	7	2
Protein kinase-like (PK-like)	KA1-like	7	2
PUA domain-like	SET domain	7	2
Surp module (SWAP domain)	Surp module (SWAP domain)	7	2
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	7	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	7	2
SNARE fusion complex	SNARE fusion complex	7	2
Toll/Interleukin receptor TIR domain	Mannose-binding lectins	7	4
E set domains	AMPKBI-like	7	2
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	7	1
ARM repeat	TPR-like	7	2
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	7	2
RING/U-box	Cysteine proteinases	7	6
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	7	4
EF-hand	P-loop containing nucleoside triphosphate hydrolases	7	3
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	7	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	7	1
Flavoproteins	Riboflavin synthase domain-like	7	3
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	6	2
DAK1/DegV-like	DhaL-like	6	3
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	6	2
PreATP-grasp domain	Single hybrid motif	6	2
WW domain	FF domain	6	3
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	6	4
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	6	3
YrdC/RibB	RibA-like	6	3
ARM repeat	Tudor/PWWP/MBT	6	3
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	6	2
Galactose oxidase, central domain	E set domains	6	2
Chromo domain-like	Homeodomain-like	6	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	6	2
Class II aaRS ABD-related	C-terminal domain of ProRS	6	2
t-snare proteins	SNARE fusion complex	6	3
RNA-binding domain, RBD	PABC (PABP) domain	6	4
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	6	2
E set domains	Ankyrin repeat	6	2
PH domain-like	RCC1/BLIP-II	6	1
E set domains	P-loop containing nucleoside triphosphate hydrolases	6	2
HD-domain/PDEase-like	Nucleotidyltransferase	6	5
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	6	4
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	6	4
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	6	3
Rudiment single hybrid motif	Single hybrid motif	6	2
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	2
Ubiquitin-like	BAG domain	6	2
Initiation factor IF2/eIF5b, domain 3	Translation proteins	6	2
Trigger factor ribosome-binding domain	FKBP-like	6	2
HIT/MYND zinc finger-like	Cysteine proteinases	6	2
Ribonuclease H-like	DNA/RNA polymerases	6	3
Thioredoxin-like	Cysteine-rich domain	6	5
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	6	2
ARM repeat	Clathrin adaptor appendage domain	6	4
RCC1/BLIP-II	FYVE/PHD zinc finger	6	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	6	2
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	6	1
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
TPR-like	CAD & PB1 domains	6	4
Homeodomain-like	FAD-linked reductases, C-terminal domain	6	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	6	2
Homeodomain-like	FAD/NAD(P)-binding domain	6	2
Surp module (SWAP domain)	Ubiquitin-like	6	1
RCC1/BLIP-II	Protein kinase-like (PK-like)	6	3
FF domain	FF domain	6	3
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	6	1
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	6	1
Translation proteins	ThrRS/AlaRS common domain	6	3
POZ domain	Pentapeptide repeat-like	6	2
POZ domain	POZ domain	6	4
Protein kinase-like (PK-like)	Ankyrin repeat	6	2
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	6	2
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	5	2
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	5	4
Ubiquitin-like	XPC-binding domain	5	3
USP8 N-terminal domain-like	JAB1/MPN domain	5	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	5	4
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	5	2
DNA-binding domain	DNA-binding pseudobarrel domain	5	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	5	1
Ribosomal L27 protein-like	Nucleic acid-binding proteins	5	2
(Phosphotyrosine protein) phosphatases II	E set domains	5	2
UBA-like	XPC-binding domain	5	3
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	1
Sec7 domain	ARM repeat	5	4
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	5	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	5	1
Ribonuclease H-like	HRDC-like	5	2
PA domain	Zn-dependent exopeptidases	5	3
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	5	2
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	5	2
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	5	2
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	5	1
PLP-dependent transferases	PLP-dependent transferases	5	4
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	5	3
PH domain-like	BEACH domain	5	4
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	5	3
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	2
Actin-crosslinking proteins	Actin-crosslinking proteins	5	1
CBS-domain pair	CAD & PB1 domains	5	3
ARID-like	HMG-box	5	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	5	1
Ankyrin repeat	RING/U-box	5	2
SPOC domain-like	C-terminal domain of Ku80	5	2
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	5	3
Acetyl-CoA synthetase-like	Protein kinase-like (PK-like)	5	1
BAR/IMD domain-like	SH3-domain	5	1
HAD-like	dsRNA-binding domain-like	5	2
BEACH domain	WD40 repeat-like	5	4
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	5	3
Carbamate kinase-like	ACT-like	5	3
Tudor/PWWP/MBT	SET domain	5	3
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	5	4
POZ domain	TPR-like	5	3
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	5	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	5	3
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	5	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	5	2
PYP-like sensor domain (PAS domain)	GAF domain-like	5	2
Rhomboid-like	UBA-like	5	2
F-box domain	WD40 repeat-like	5	2
Zinc beta-ribbon	Cyclin-like	5	2
Tudor/PWWP/MBT	FYVE/PHD zinc finger	5	3
SWIB/MDM2 domain	Plus3-like	5	5
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	5	3
CCCH zinc finger	RING/U-box	5	2
PP2C-like	Protein kinase-like (PK-like)	5	3
GAF domain-like	GAF domain-like	5	2
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	5	3
Translation proteins	Translation proteins	5	1
L domain-like	WD40 repeat-like	5	5
Ubiquitin-like	Zn-binding ribosomal proteins	5	1
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	5	2
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	4	2
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	4	3
PLP-binding barrel	Alanine racemase C-terminal domain-like	4	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
RING/U-box	PUA domain-like	4	3
RING/U-box	Ran binding protein zinc finger-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	2
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	4	2
HAD-like	BRCT domain	4	2
NAD(P)-binding Rossmann-fold domains	Citrate synthase	4	1
WD40 repeat-like	SNARE fusion complex	4	3
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	4	4
Thioredoxin-like	Ubiquitin-like	4	3
P-loop containing nucleoside triphosphate hydrolases	vWA-like	4	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	4	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
CAD & PB1 domains	RING/U-box	4	2
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	4	3
F-box domain	HCP-like	4	3
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
EF-hand	Mitochondrial carrier	4	2
PAZ domain	RNase III domain-like	4	4
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	4	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	4	2
Ubiquitin-like	Acid proteases	4	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	4	4
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	4	4
PH domain-like	WD40 repeat-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	3
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	4	2
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	4	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	4	4
Acetyl-CoA synthetase-like	ACP-like	4	2
ClpP/crotonase	ClpP/crotonase	4	3
FAD/NAD(P)-binding domain	EF-hand	4	3
RING/U-box	UBA-like	4	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	4	2
GAF domain-like	CheY-like	4	3
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	4	3
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	4	2
Dom34/Pelota N-terminal domain-like	L30e-like	4	1
Actin-crosslinking proteins	(Trans)glycosidases	4	1
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	4	4
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	4	4
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	4	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	4	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	4	3
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
SMAD/FHA domain	Phospholipase D/nuclease	4	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	4	1
PA domain	Transferrin receptor-like dimerisation domain	4	2
Glutamine synthetase/guanido kinase	GatB/YqeY motif	4	2
RNA-binding domain, RBD	DPP6 N-terminal domain-like	4	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	4	2
ARM repeat	Subdomain of clathrin and coatomer appendage domain	4	3
vWA-like	SPOC domain-like	4	3
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	4	2
SWIB/MDM2 domain	SWIB/MDM2 domain	4	2
Cytidine deaminase-like	Dihydrofolate reductase-like	4	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
Dom34/Pelota N-terminal domain-like	Translational machinery components	4	1
Arp2/3 complex subunits	Arp2/3 complex subunits	4	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
PRTase-like	PRTase-like	4	2
FKBP-like	Triger factor/SurA peptide-binding domain-like	4	1
EF-hand	Calponin-homology domain, CH-domain	4	2
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	4	3
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	4	2
GST C-terminal domain-like	eEF-1beta-like	4	2
Ubiquitin-like	Protein kinase-like (PK-like)	4	2
Clathrin heavy-chain terminal domain	ARM repeat	4	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	4	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	4	2
SET domain	Formin homology 2 domain (FH2 domain)	4	2
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	4	2
ARID-like	FYVE/PHD zinc finger	4	2
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	4	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	4	2
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	4	2
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	4	1
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	4	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	4	2
Chitinase insertion domain	Protein kinase-like (PK-like)	4	1
TPR-like	Chaperone J-domain	4	3
PH domain-like	Bet v1-like	4	1
Chaperone J-domain	4Fe-4S ferredoxins	4	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	4	2
GINS helical bundle-like	PriA/YqbF domain	4	2
Thioredoxin-like	TPR-like	4	3
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	4
Ubiquitin-like	PUG domain-like	4	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	4	2
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	4	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	4	2
Taf5 N-terminal domain-like	WD40 repeat-like	4	1
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	4	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	4	2
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	4
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	4	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	4	3
(Trans)glycosidases	(Trans)glycosidases	4	3
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	4	1
Carbamate kinase-like	ALDH-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	3	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	3	3
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	3	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	3	3
Kelch motif	Metallo-dependent phosphatases	3	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	3	1
Ricin B-like lectins	Glycosyl hydrolase domain	3	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	3	2
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	3	1
Ubiquitin-like	HAD-like	3	1
Chaperone J-domain	RNA-binding domain, RBD	3	2
BSD domain-like	BSD domain-like	3	1
SAP domain	FYVE/PHD zinc finger	3	2
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	3	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	3	1
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	3
CAD & PB1 domains	UBA-like	3	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	3	3
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
Ubiquitin-like	Hect, E3 ligase catalytic domain	3	2
Cysteine proteinases	Galactose-binding domain-like	3	3
TolB, C-terminal domain	Quinoprotein alcohol dehydrogenase-like	3	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	3	2
Thioredoxin-like	NHL repeat	3	2
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	3	2
Aspartate/glutamate racemase	Aspartate/glutamate racemase	3	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	3	1
Protein kinase-like (PK-like)	UBA-like	3	1
cAMP-binding domain-like	cAMP-binding domain-like	3	2
TPR-like	SET domain	3	3
TPR-like	HSP20-like chaperones	3	2
FYSH domain	beta-beta-alpha zinc fingers	3	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	1
Trypsin-like serine proteases	Trypsin-like serine proteases	3	2
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	3	2
F-box domain	ApaG-like	3	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
beta-sandwich domain of Sec23/24	RNA-binding domain, RBD	3	3
HIT-like	HIT-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Outer arm dynein light chain 1	3	2
Methylglyoxal synthase-like	Cytidine deaminase-like	3	2
PH domain-like	ARM repeat	3	3
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	3	2
FYVE/PHD zinc finger	Homeodomain-like	3	2
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	3	2
Nucleotidylyl transferase	Nucleotidylyl transferase	3	1
Cytochrome f, large domain	Rudiment single hybrid motif	3	2
PAH2 domain	PAH2 domain	3	1
Cap-Gly domain	Ubiquitin-like	3	2
TolB, C-terminal domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
Plus3-like	GYF domain	3	3
DUSP-like	Cysteine proteinases	3	2
SBT domain	Ankyrin repeat	3	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	3	2
Nucleoporin domain	WD40 repeat-like	3	3
F-box domain	Actin-like ATPase domain	3	1
Galactose oxidase, central domain	Galactose oxidase, central domain	3	1
Cytochrome P450	Cytochrome P450	3	3
HAD-like	NHL repeat	3	2
PurM N-terminal domain-like	PurM C-terminal domain-like	3	2
NTF2-like	Probable bacterial effector-binding domain	3	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	3	2
HAD-like	Riboflavin kinase-like	3	1
FAD/NAD(P)-binding domain	ACP-like	3	1
GroEL apical domain-like	SAICAR synthase-like	3	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	3	2
Tudor/PWWP/MBT	Tudor/PWWP/MBT	3	1
Sec63 N-terminal domain-like	E set domains	3	2
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	3	1
TATA-box binding protein-like	TATA-box binding protein-like	3	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	3	3
PAZ domain	dsRNA-binding domain-like	3	3
ARID-like	HSP20-like chaperones	3	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	3	2
Dcp2 domain-like	Nudix	3	2
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	3	3
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	3	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	3	2
UBC-like	RING/U-box	3	2
Double Clp-N motif	Double Clp-N motif	3	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	3	1
L domain-like	Ubiquitin-like	3	2
SWIB/MDM2 domain	GYF domain	3	3
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
UBA-like	Hect, E3 ligase catalytic domain	3	2
SWIB/MDM2 domain	eIF1-like	3	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
L30e-like	alpha/beta knot	3	1
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	3	1
PreATP-grasp domain	PreATP-grasp domain	3	2
Staphylococcal nuclease	Staphylococcal nuclease	3	2
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	3	1
F-box domain	SMI1/KNR4-like	3	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	3	1
PUA domain-like	Nucleotidylyl transferase	3	1
SMI1/KNR4-like	ApaG-like	3	1
RNI-like	Glutathione synthetase ATP-binding domain-like	3	1
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	3	1
PLC-like phosphodiesterases	PLC-like phosphodiesterases	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	2
Cysteine proteinases	Formin homology 2 domain (FH2 domain)	3	1
WGR domain-like	ADP-ribosylation	3	3
C-terminal, gelsolin-like domain of Sec23/24	Actin depolymerizing proteins	3	2
Tricorn protease domain 2	WD40 repeat-like	3	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	3	1
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	3	1
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	3	1
HAD-like	Thioredoxin-like	3	2
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	3	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	3	1
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	3	1
Cystatin/monellin	Cystatin/monellin	3	1
PH domain-like	BSD domain-like	3	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	1
FYSH domain	Hypothetical protein AF0491, middle domain	3	1
YjgF-like	YjgF-like	3	3
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
Restriction endonuclease-like	RuvA domain 2-like	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	3	1
ACP-like	Trimeric LpxA-like enzymes	3	1
Six-hairpin glycosidases	AbfB domain	3	2
Amidase signature (AS) enzymes	TPR-like	3	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	3	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	3	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	3	2
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	3	2
PUA domain-like	SWIB/MDM2 domain	3	1
Saposin	Saposin	3	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	3	2
Granulin repeat	Formin homology 2 domain (FH2 domain)	3	1
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	3	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	3	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	3	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	3	2
LEA14-like	LEA14-like	3	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
HisI-like	all-alpha NTP pyrophosphatases	3	2
ARM repeat	UBA-like	3	2
PUA domain-like	eIF1-like	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	3	2
TPR-like	PUA domain-like	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	1
Actin-like ATPase domain	AF1104-like	3	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	3	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	3	3
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	3	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	3	3
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	3	1
WD40 repeat-like	DNase I-like	3	1
UBA-like	KA1-like	3	1
Ubiquitin-like	Cysteine proteinases	3	2
ACP-like	Heme-dependent catalase-like	3	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	3	2
PH domain-like	Phospholipase D/nuclease	3	2
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
PUA domain-like	Ribosomal protein S5 domain 2-like	2	2
BRCT domain	WGR domain-like	2	2
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
WD40 repeat-like	Tricorn protease N-terminal domain	2	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	2	2
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	2	2
RNA-binding domain, RBD	ENTH/VHS domain	2	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	2	1
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	2	1
vWA-like	C-terminal domain of Ku80	2	1
PDZ domain-like	PDZ domain-like	2	1
TPR-like	SMR domain-like	2	2
F-box domain	HIT/MYND zinc finger-like	2	2
Formin homology 2 domain (FH2 domain)	RING/U-box	2	2
Terpenoid synthases	Terpenoid synthases	2	2
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
PH domain-like	Prismane protein-like	2	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	2	1
PH domain-like	ArfGap/RecO-like zinc finger	2	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
Ribonuclease H-like	Ribonuclease H-like	2	2
DNA clamp	DNA clamp	2	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	2	1
"Winged helix" DNA-binding domain	E set domains	2	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
RNA-binding domain, RBD	TPR-like	2	2
ARM repeat	"Winged helix" DNA-binding domain	2	1
HD-domain/PDEase-like	TGS-like	2	2
Second domain of FERM	PH domain-like	2	1
F-box domain	SET domain	2	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	2	2
Urease, gamma-subunit	Metallo-dependent hydrolases	2	2
Cytidine deaminase-like	YbiA-like	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	2
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	2	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	2	1
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	2
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	2	2
HAD-like	NTF2-like	2	2
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
YjeF N-terminal domain-like	FMN-binding split barrel	2	2
Concanavalin A-like lectins/glucanases	Cysteine proteinases	2	1
RING/U-box	Cyclophilin-like	2	1
Clavaminate synthase-like	RING/U-box	2	1
FYVE/PHD zinc finger	Plus3-like	2	2
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	2	1
Kix domain of CBP (creb binding protein)	F-box domain	2	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	2	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	2	2
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Thioredoxin-like	FAD-dependent thiol oxidase	2	1
Nucleotide-binding domain	FAD/NAD(P)-binding domain	2	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Cullin homology domain	Cullin homology domain	2	1
Surp module (SWAP domain)	ENTH/VHS domain	2	1
ITPase-like	ITPase-like	2	1
FAD/NAD(P)-binding domain	SMAD/FHA domain	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	2
Putative DNA-binding domain	PheT/TilS domain	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	2	1
Formin homology 2 domain (FH2 domain)	RuBisCo LSMT C-terminal, substrate-binding domain	2	1
PapD-like	Ankyrin repeat	2	2
GST C-terminal domain-like	Nucleic acid-binding proteins	2	1
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	2	1
TPR-like	HIT/MYND zinc finger-like	2	2
WD40 repeat-like	Calcium-dependent phosphotriesterase	2	2
Oxidoreductase molybdopterin-binding domain	E set domains	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
Alpha-L RNA-binding motif	Pseudouridine synthase	2	1
Chaperone J-domain	Thioredoxin-like	2	2
F-box domain	L domain-like	2	2
FYVE/PHD zinc finger	ARM repeat	2	1
GroEL-intermediate domain like	GroEL-intermediate domain like	2	1
Ribonuclease H-like	RING/U-box	2	2
HCP-like	HIT/MYND zinc finger-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	2	2
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	2
Putative DNA-binding domain	Class II aaRS and biotin synthetases	2	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	2	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	2	1
HD-domain/PDEase-like	EF-hand	2	1
"Winged helix" DNA-binding domain	Zinc beta-ribbon	2	1
Nucleotide-diphospho-sugar transferases	ARM repeat	2	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	2	2
Tropomyosin	Tropomyosin	2	2
PP2C-like	cAMP-binding domain-like	2	1
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	2	1
Trimeric LpxA-like enzymes	ARM repeat	2	1
Urease, gamma-subunit	Urease, beta-subunit	2	2
Nucleotidylyl transferase	Tropomyosin	2	1
RNI-like	Outer arm dynein light chain 1	2	2
BAR/IMD domain-like	Ankyrin repeat	2	2
alpha-D-mannose-specific plant lectins	CBS-domain pair	2	2
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
ARM repeat	BEACH domain	2	2
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
SAP domain	RNA-binding domain, RBD	2	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	2	1
Formyltransferase	FMT C-terminal domain-like	2	1
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	2	1
FYVE/PHD zinc finger	SWIB/MDM2 domain	2	2
PX domain	BAR/IMD domain-like	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	2	2
Concanavalin A-like lectins/glucanases	PH domain-like	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	2	1
BRCT domain	ADP-ribosylation	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
RNA-binding domain, RBD	PWI domain	2	1
Cyclophilin-like	Retrovirus zinc finger-like domains	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
TATA-box binding protein-like	DNA-glycosylase	2	1
Nucleotidyltransferase	TGS-like	2	2
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	2	1
RNA-binding domain, RBD	WW domain	2	2
DNase I-like	EF-hand	2	2
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	2
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	2	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
RNI-like	WD40 repeat-like	2	2
PDZ domain-like	TPR-like	2	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	2	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	2	1
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	2	1
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	2	2
RmlC-like cupins	RmlC-like cupins	2	2
Protein kinase-like (PK-like)	Activating enzymes of the ubiquitin-like proteins	2	2
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	2	1
alpha-D-mannose-specific plant lectins	EGF/Laminin	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
UraD-Like	Transthyretin (synonym: prealbumin)	2	1
RNI-like	SET domain	2	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	2	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	2	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
Pre-PUA domain	PUA domain-like	2	1
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	2	2
Thioredoxin-like	"Winged helix" DNA-binding domain	2	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	2	2
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	1
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	1
PIN domain-like	Chromo domain-like	2	1
Thioredoxin-like	ERP29 C domain-like	2	1
TPR-like	Metallo-dependent phosphatases	2	1
Thioredoxin-like	Six-hairpin glycosidases	2	2
Tropomyosin	Apolipoprotein A-I	2	2
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	2	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	2	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	2	1
Urease, beta-subunit	Metallo-dependent hydrolases	2	2
Ran binding protein zinc finger-like	Translation proteins	2	1
BAR/IMD domain-like	PH domain-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	2	1
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	2	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	2	2
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	2	2
Protein prenylyltransferase	L domain-like	2	1
ISP transmembrane anchor	ISP domain	2	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	2
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	2	2
HCP-like	Homing endonucleases	2	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
PYP-like sensor domain (PAS domain)	F-box domain	2	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
EF-hand	RING/U-box	2	2
PH domain-like	Ankyrin repeat	2	2
Carbamate kinase-like	Carbamate kinase-like	2	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
F-box domain	Clavaminate synthase-like	2	2
E set domains	CBS-domain pair	2	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	2	2
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
Acid proteases	UBA-like	2	2
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Class II aaRS and biotin synthetases	Translation proteins	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	2	2
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
BRCT domain	post-AAA+ oligomerization domain-like	2	1
Putative DNA-binding domain	Putative DNA-binding domain	2	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	2	1
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	2	1
PheT/TilS domain	Class II aaRS and biotin synthetases	2	1
POZ domain	Galactose-binding domain-like	2	1
ARM repeat	Concanavalin A-like lectins/glucanases	2	2
Enolase N-terminal domain-like	alpha/beta-Hydrolases	2	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
ARM repeat	SH3-domain	2	1
Second domain of FERM	Prismane protein-like	2	1
Cap-Gly domain	L domain-like	2	1
Heme oxygenase-like	HAD-like	2	2
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	2	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Dihydrofolate reductase-like	YbiA-like	2	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	2
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	2	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
CCCH zinc finger	HIT-like	2	2
Cyclophilin-like	TPR-like	2	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	2	1
L9 N-domain-like	Ribosomal protein L9 C-domain	2	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	2	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	2	1
E set domains	RNA-binding domain, RBD	2	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
PRP4-like	WD40 repeat-like	2	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	1
PH domain-like	HMG-box	2	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	2	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	2	1
Ankyrin repeat	TPR-like	2	1
Nucleoside hydrolase	Nucleoside hydrolase	2	1
Nucleotidyltransferase	EF-hand	2	1
Putative cyclase	Putative cyclase	2	1
Histone-fold	ARM repeat	2	1
Kix domain of CBP (creb binding protein)	RNI-like	2	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	2	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	1
UBA-like	Thioredoxin-like	2	1
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	2
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
POZ domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
TPR-like	RNI-like	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
MFS general substrate transporter	PUA domain-like	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
Arabinanase/levansucrase/invertase	Arabinanase/levansucrase/invertase	1	1
Protein kinase-like (PK-like)	Formin homology 2 domain (FH2 domain)	1	1
(Phosphotyrosine protein) phosphatases II	P-loop containing nucleoside triphosphate hydrolases	1	1
PRC-barrel domain	PRC-barrel domain	1	1
EF-hand	TPR-like	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
F-box domain	YWTD domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
Aminoacid dehydrogenase-like, N-terminal domain	CBS-domain pair	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
DNA-glycosylase	Nudix	1	1
AN1-like Zinc finger	beta-beta-alpha zinc fingers	1	1
TAZ domain	RING/U-box	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Ribosomal protein S2	Nucleotide-diphospho-sugar transferases	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Helical scaffold and wing domains of SecA	Helical scaffold and wing domains of SecA	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Nucleoporin domain	Quinoprotein alcohol dehydrogenase-like	1	1
Toll/Interleukin receptor TIR domain	Homeodomain-like	1	1
Skp1 dimerisation domain-like	L domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
L domain-like	HMA, heavy metal-associated domain	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
WD40 repeat-like	TPR-like	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
SMAD/FHA domain	BRCT domain	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Amine oxidase catalytic domain	Amine oxidase catalytic domain	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
BRCT domain	DNA/RNA polymerases	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
Tudor/PWWP/MBT	RNA-binding domain, RBD	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
L domain-like	EF-hand	1	1
Macro domain-like	HIT-like	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
RNI-like	ARM repeat	1	1
SAP domain	DNase I-like	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
Ubiquitin-like	Homeodomain-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
DNase I-like	DNase I-like	1	1
PurS-like	PurM C-terminal domain-like	1	1
NAD(P)-binding Rossmann-fold domains	CBS-domain pair	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
HD-domain/PDEase-like	ACT-like	1	1
alpha-D-mannose-specific plant lectins	Quinoprotein alcohol dehydrogenase-like	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
DAK1/DegV-like	Ribosomal protein S5 domain 2-like	1	1
Carboxypeptidase regulatory domain-like	Cna protein B-type domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Toll/Interleukin receptor TIR domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
L domain-like	Calcium-dependent phosphotriesterase	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
PUA domain-like	alpha/beta knot	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
P-loop containing nucleoside triphosphate hydrolases	Cyclin-like	1	1
PHL pollen allergen	PHL pollen allergen	1	1
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
Protease propeptides/inhibitors	PA domain	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Cysteine proteinases	UBA-like	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Protein kinase-like (PK-like)	PLP-dependent transferases	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
Ubiquitin-like	Galactose-binding domain-like	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	1	1
SPOC domain-like	SAP domain	1	1
ssDNA-binding transcriptional regulator domain	Retrovirus zinc finger-like domains	1	1
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
GYF domain	CCCH zinc finger	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
C-terminal UvrC-binding domain of UvrB	ApaG-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
BRCT domain	Nucleotidyltransferase	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
R3H domain	Ankyrin repeat	1	1
Tex N-terminal region-like	SH2 domain	1	1
ARID-like	Clavaminate synthase-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
Ankyrin repeat	Subtilisin-like	1	1
SMAD/FHA domain	PP2C-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
Pectin lyase-like	Pectin lyase-like	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
Starch-binding domain-like	Phosphoglycerate mutase-like	1	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	1	1
E set domains	E set domains	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Calcium ATPase, transduction domain A	ARM repeat	1	1
FAH	FAH	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
Chaperone J-domain	E set domains	1	1
SAP domain	ADP-ribosylation	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
Single hybrid motif	ClpP/crotonase	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Ammonium transporter	Ammonium transporter	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
YgbK-like	Aldolase	1	1
ARM repeat	POZ domain	1	1
HCP-like	Chaperone J-domain	1	1
Hypothetical protein PA1324	Cna protein B-type domain	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
S13-like H2TH domain	Ribosomal protein S5 domain 2-like	1	1
DPP6 N-terminal domain-like	Protein kinase-like (PK-like)	1	1
alpha/beta-Hydrolases	Formin homology 2 domain (FH2 domain)	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
Chaperone J-domain	CSL zinc finger	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
SSo0622-like	Kelch motif	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
TGS-like	ACT-like	1	1
vWA-like	SAP domain	1	1
FYVE/PHD zinc finger	TPR-like	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Single hybrid motif	Single hybrid motif	1	1
Putative isomerase YbhE	RING/U-box	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
RNA-binding domain, RBD	Formin homology 2 domain (FH2 domain)	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNA-binding domain	FYVE/PHD zinc finger	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	P-loop containing nucleoside triphosphate hydrolases	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Mitochondrial carrier	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
SAP domain	SAP domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PABC (PABP) domain	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
F-box domain	Tricorn protease domain 2	1	1
F-box domain	Putative isomerase YbhE	1	1
Ubiquitin-like	Bromodomain	1	1
Smc hinge domain	Tropomyosin	1	1
Cyclophilin-like	RNA-binding domain, RBD	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
CarD-like	TRCF domain-like	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
NAD(P)-binding Rossmann-fold domains	Mitochondrial carrier	1	1
SWIB/MDM2 domain	CCCH zinc finger	1	1
Ran binding protein zinc finger-like	DNase I-like	1	1
BRCT domain	PsbU/PolX domain-like	1	1
SAP domain	WGR domain-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
alpha-D-mannose-specific plant lectins	Clc chloride channel	1	1
Quinoprotein alcohol dehydrogenase-like	SNARE fusion complex	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	NAD(P)-binding Rossmann-fold domains	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
UBA-like	PUG domain-like	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Protein kinase-like (PK-like)	PH domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
F-box domain	Pectin lyase-like	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
Hypothetical protein PA1324	Carboxypeptidase regulatory domain-like	1	1
beta-sandwich domain of Sec23/24	Band 7/SPFH domain	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
Starch-binding domain-like	Cna protein B-type domain	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein cytoplasmic domain-like	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
Pseudouridine synthase	PUA domain-like	1	1
Macro domain-like	Macro domain-like	1	1
UBA-like	post-AAA+ oligomerization domain-like	1	1
GAT-like domain	GAT-like domain	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
PUA domain-like	PUA domain-like	1	1
POZ domain	WD40 repeat-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
F-box domain	NTF2-like	1	1
(Phosphotyrosine protein) phosphatases II	Toll/Interleukin receptor TIR domain	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Flavoproteins	Radical SAM enzymes	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
HMG-box	HMG-box	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
TAZ domain	FYVE/PHD zinc finger	1	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
Chromo domain-like	Ankyrin repeat	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
beta-sandwich domain of Sec23/24	NAD(P)-binding Rossmann-fold domains	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
AF0104/ALDC/Ptd012-like	L domain-like	1	1
Hypothetical protein PA1324	Starch-binding domain-like	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
DAK1/DegV-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Formin homology 2 domain (FH2 domain)	P-loop containing nucleoside triphosphate hydrolases	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	1	1
POZ domain	Actin-crosslinking proteins	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
Chaperone J-domain	Homeodomain-like	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	1	1
L domain-like	FabD/lysophospholipase-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
NAD(P)-linked oxidoreductase	NAD(P)-linked oxidoreductase	1	1
CinA-like	Nucleotidylyl transferase	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Cytochrome b559 subunits	Cytochrome b559 subunits	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	1	1
TAZ domain	TAZ domain	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
Formin homology 2 domain (FH2 domain)	TPR-like	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
Thioredoxin-like	VC0467-like	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
SH2 domain	SH2 domain	1	1
Bromodomain	FYVE/PHD zinc finger	1	1
SRF-like	DNase I-like	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
SufE/NifU	BolA-like	1	1
BRCT domain	FYVE/PHD zinc finger	1	1
DhaL-like	DhaL-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
alpha-D-mannose-specific plant lectins	DPP6 N-terminal domain-like	1	1
WD40 repeat-like	Soluble quinoprotein glucose dehydrogenase	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	S13-like H2TH domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
Photosystem I reaction center subunit XI, PsaL	Photosystem I reaction center subunit XI, PsaL	1	1
Ribosomal protein L22	Ribosomal protein S3 C-terminal domain	1	1
Pseudo ankyrin repeat-like	Ankyrin repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
L domain-like	ARM repeat	1	1
vWA-like	Cysteine-rich domain	1	1
RNI-like	EF-hand	1	1
SufE/NifU	NadA-like	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
ACT-like	Formyltransferase	1	1
DPP6 N-terminal domain-like	DPP6 N-terminal domain-like	1	1
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Translation proteins	PRC-barrel domain	1	1
GYF domain	RNA-binding domain, RBD	1	1
TGS-like	Class II aaRS ABD-related	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	"Winged helix" DNA-binding domain	1	1
L domain-like	Cyclin-like	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
WD40 repeat-like	Cyclophilin-like	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
Clavaminate synthase-like	Clavaminate synthase-like	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
PDZ domain-like	Rubredoxin-like	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
FYVE/PHD zinc finger	GYF domain	1	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
Acyl-CoA binding protein	Kelch motif	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
WD40 repeat-like	Bromodomain	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
Nucleotidyltransferase	ACT-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Kix domain of CBP (creb binding protein)	Kix domain of CBP (creb binding protein)	1	1
E set domains	Riboflavin synthase domain-like	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
Nucleic acid-binding proteins	UBA-like	1	1
Ribonuclease H-like	SH2 domain	1	1
PurS-like	PurM N-terminal domain-like	1	1
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
UBC-like	UBA-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Plus3-like	CCCH zinc finger	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Ubiquitin-like	TPR-like	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
Amine oxidase catalytic domain	ARM repeat	1	1
Lipoxigenase	Lipoxigenase	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
N-terminal domain of the delta subunit of the F1F0-ATP synthase	N-terminal domain of the delta subunit of the F1F0-ATP synthase	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
Six-hairpin glycosidases	Carbohydrate-binding domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
beta-sandwich domain of Sec23/24	P-loop containing nucleoside triphosphate hydrolases	1	1
Lysozyme-like	Lysozyme-like	1	1
RuvA domain 2-like	SH2 domain	1	1
Aminopeptidase/glucanase lid domain	Aminopeptidase/glucanase lid domain	1	1
SAP domain	CCCH zinc finger	1	1
GYF domain	SET domain	1	1
Amine oxidase N-terminal region	ARM repeat	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
Skp1 dimerisation domain-like	Actin-crosslinking proteins	1	1
PH domain-like	GTPase activation domain, GAP	1	1
Chaperone J-domain	ARM repeat	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
DNA-binding domain	Bromodomain	1	1
WW domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
beta-sandwich domain of Sec23/24	Galactose-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein transmembrane domain-like	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
Quinoprotein alcohol dehydrogenase-like	Calcium-dependent phosphotriesterase	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1