Domain combination pairs in Eucalyptus grandis v201

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1443 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
L domain-like	L domain-like	694	127
P-loop containing nucleoside triphosphate hydrolases	L domain-like	639	99
Protein kinase-like (PK-like)	L domain-like	636	44
L domain-like	RNI-like	390	108
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	338	68
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	308	14
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	306	65
GroES-like	NAD(P)-binding Rossmann-fold domains	206	8
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	204	41
Toll/Interleukin receptor TIR domain	L domain-like	198	46
RNI-like	Protein kinase-like (PK-like)	179	31
Toll/Interleukin receptor TIR domain	"Winged helix" DNA-binding domain	146	25
Thioredoxin-like	GST C-terminal domain-like	138	7
"Winged helix" DNA-binding domain	L domain-like	132	29
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	131	5
Cupredoxins	Cupredoxins	128	14
RNA-binding domain, RBD	RNA-binding domain, RBD	124	28
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	111	19
RNI-like	RNI-like	109	49
HAD-like	Calcium ATPase, transmembrane domain M	106	19
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	104	19
Calcium ATPase, transduction domain A	HAD-like	99	15
F-box domain	RNI-like	95	10
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	89	5
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	88	2
ABC transporter transmembrane region	ABC transporter transmembrane region	87	11
TPR-like	TPR-like	86	21
Actin-like ATPase domain	Actin-like ATPase domain	73	17
P-loop containing nucleoside triphosphate hydrolases	RNI-like	73	39
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	72	13
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	69	11
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	69	10
ARM repeat	RING/U-box	68	10
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	66	7
ARM repeat	ARM repeat	65	26
Periplasmic binding protein-like I	Periplasmic binding protein-like II	64	7
Thiolase-like	Thiolase-like	55	2
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	54	10
Voltage-gated potassium channels	cAMP-binding domain-like	54	6
Galactose-binding domain-like	(Trans)glycosidases	54	11
(Trans)glycosidases	Glycosyl hydrolase domain	53	10
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	53	6
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	51	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	48	7
Protein kinase-like (PK-like)	EF-hand	48	2
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	48	7
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	47	7
RING/U-box	RING/U-box	43	21
Barwin-like endoglucanases	PHL pollen allergen	43	2
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	43	3
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	40	14
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	40	4
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	38	7
Cyclin-like	Cyclin-like	37	7
TRAF domain-like	TRAF domain-like	37	4
Homeodomain-like	Homeodomain-like	36	11
GroES-like	GroES-like	36	5
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	35	7
ENTH/VHS domain	GAT-like domain	35	5
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	34	10
CCCH zinc finger	CCCH zinc finger	32	20
Galactose-binding domain-like	Galactose-binding domain-like	31	4
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	31	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	31	6
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	30	8
F-box domain	Galactose oxidase, central domain	30	3
ACT-like	ACT-like	30	11
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	29	7
WD40 repeat-like	WD40 repeat-like	29	15
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	29	14
Thioredoxin-like	Thioredoxin-like	29	16
Cullin homology domain	"Winged helix" DNA-binding domain	28	4
Cullin repeat-like	Cullin homology domain	28	3
Phospholipase D/nuclease	Phospholipase D/nuclease	28	12
SNARE-like	SNARE fusion complex	28	3
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	28	7
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	27	13
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	27	2
DHS-like NAD/FAD-binding domain	Thiamin diphosphate-binding fold (THDP-binding)	26	4
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	26	5
Galactose mutarotase-like	(Trans)glycosidases	26	5
ARM repeat	Protein kinase-like (PK-like)	26	13
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	26	3
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	25	5
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	25	6
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	25	5
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	25	1
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	24	3
Cullin repeat-like	"Winged helix" DNA-binding domain	24	2
YhbY-like	YhbY-like	24	8
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	24	8
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	24	4
DNA-binding domain	DNA-binding domain	24	4
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	23	11
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	23	10
WRKY DNA-binding domain	WRKY DNA-binding domain	23	2
Nucleic acid-binding proteins	Nucleic acid-binding proteins	22	16
Homeodomain-like	Bet v1-like	22	3
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	22	3
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	22	4
Trypsin-like serine proteases	PDZ domain-like	22	5
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	22	2
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	22	8
Nucleotide-diphospho-sugar transferases	RING/U-box	21	3
F-box domain	Kelch motif	21	3
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	21	3
PAZ domain	Ribonuclease H-like	21	2
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	21	7
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	21	11
Galactose mutarotase-like	Glycosyl hydrolase domain	21	2
Ankyrin repeat	Ankyrin repeat	21	5
DNA-binding pseudobarrel domain	CAD & PB1 domains	21	4
(Trans)glycosidases	Chitinase insertion domain	20	3
GroEL equatorial domain-like	GroEL apical domain-like	20	3
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	20	6
Ubiquitin-like	UBA-like	20	8
CHY zinc finger-like	Zinc hairpin stack	20	5
GroEL-intermediate domain like	GroEL apical domain-like	20	3
Bet v1-like	Bet v1-like	20	6
GroEL equatorial domain-like	GroEL-intermediate domain like	20	3
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	20	3
Mannose-binding lectins	Mannose-binding lectins	20	12
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	20	3
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	19	3
CHY zinc finger-like	RING/U-box	19	4
Zinc hairpin stack	RING/U-box	19	4
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	19	4
vWA-like	RING/U-box	18	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	18	2
Toll/Interleukin receptor TIR domain	RNI-like	18	14
POZ domain	Skp1 dimerisation domain-like	18	4
EF-hand	Voltage-gated potassium channels	18	8
TPR-like	HCP-like	18	7
Clc chloride channel	CBS-domain pair	18	6
PK beta-barrel domain-like	PK C-terminal domain-like	18	2
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	18	9
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	18	9
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	18	3
Protein kinase-like (PK-like)	RING/U-box	18	4
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	18	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	17	2
FYVE/PHD zinc finger	FYVE/PHD zinc finger	17	10
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	17	4
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	17	6
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	17	4
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	16	6
CCCH zinc finger	WD40 repeat-like	16	1
Translation proteins	EF-G C-terminal domain-like	16	7
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	16	7
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	16	2
Translation proteins SH3-like domain	Nucleic acid-binding proteins	16	5
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	16	4
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	16	3
EF-G C-terminal domain-like	EF-G C-terminal domain-like	16	7
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	16	4
dsRNA-binding domain-like	dsRNA-binding domain-like	16	9
Voltage-gated potassium channels	Voltage-gated potassium channels	16	7
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	16	3
Subtilisin-like	PA domain	16	4
UROD/MetE-like	UROD/MetE-like	16	2
Cysteine-rich domain	Cysteine-rich domain	16	11
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	15	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	15	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	15	5
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	15	2
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	15	5
Voltage-gated potassium channels	Ankyrin repeat	15	2
cAMP-binding domain-like	Ankyrin repeat	15	2
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	15	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	15	3
CCCH zinc finger	RNA-binding domain, RBD	15	4
NAD(P)-binding Rossmann-fold domains	Aldolase	15	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	15	5
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	15	9
Ubiquitin-like	Ubiquitin-like	15	6
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	14	3
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	14	5
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	14	1
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	14	2
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	14	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	14	5
ENT-like	Tudor/PWWP/MBT	14	2
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	14	3
NAD(P)-binding Rossmann-fold domains	ACT-like	14	4
Plant lectins/antimicrobial peptides	Lysozyme-like	14	1
WD40 repeat-like	ARM repeat	14	10
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	14	5
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	14	5
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	14	4
EF-hand	EF-hand	13	5
Chromo domain-like	Chromo domain-like	13	5
Growth factor receptor domain	Protein kinase-like (PK-like)	13	2
NTF2-like	RNA-binding domain, RBD	13	2
HCP-like	HCP-like	13	7
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	13	6
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	13	7
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	13	6
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	13	6
FKBP-like	TPR-like	13	3
PH domain-like	FYVE/PHD zinc finger	13	2
FAS1 domain	FAS1 domain	13	4
Single hybrid motif	CoA-dependent acyltransferases	12	5
TRAF domain-like	POZ domain	12	3
"Winged helix" DNA-binding domain	RNI-like	12	10
CBS-domain pair	CBS-domain pair	12	8
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	12	2
EGF/Laminin	Protein kinase-like (PK-like)	12	4
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	12	2
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	12	5
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	12	2
EF-hand	PLC-like phosphodiesterases	12	3
CAD & PB1 domains	Protein kinase-like (PK-like)	12	2
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	12	3
PreATP-grasp domain	Rudiment single hybrid motif	12	5
Galactose-binding domain-like	Galactose mutarotase-like	12	3
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	12	3
RCC1/BLIP-II	RCC1/BLIP-II	12	3
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	12	6
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	12	7
Serine metabolism enzymes domain	ACT-like	12	3
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	12	4
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	12	4
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	12	6
Acid proteases	Saposin	12	3
TRAF domain-like	Cysteine proteinases	11	2
WD40 repeat-like	RING/U-box	11	8
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	11	2
Ankyrin repeat	POZ domain	11	5
"Winged helix" DNA-binding domain	Homeodomain-like	11	3
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	11	5
ACT-like	Protein kinase-like (PK-like)	11	1
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	11	6
Galactose mutarotase-like	Starch-binding domain-like	11	2
BRCT domain	BRCT domain	11	5
Tricorn protease domain 2	alpha/beta-Hydrolases	11	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	11	8
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	11	8
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	11	5
Starch-binding domain-like	Galactose-binding domain-like	11	2
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	11	6
E set domains	(Trans)glycosidases	10	6
MFS general substrate transporter	MFS general substrate transporter	10	2
HMA, heavy metal-associated domain	HAD-like	10	7
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	10	4
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	10	4
Cysteine proteinases	Sec-C motif	10	5
Amine oxidase N-terminal region	Amine oxidase N-terminal region	10	4
Protease propeptides/inhibitors	Subtilisin-like	10	3
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	10	6
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	10	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	10	8
LysM domain	Protein kinase-like (PK-like)	10	3
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	10	4
PA domain	RING/U-box	10	2
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	10	7
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	10	5
TPR-like	Protein kinase-like (PK-like)	10	3
RING/U-box	TPR-like	9	4
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	9	5
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	9	2
CheY-like	Homeodomain-like	9	2
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	9	3
Actin depolymerizing proteins	Actin depolymerizing proteins	9	5
FKBP-like	FKBP-like	9	2
PGBD-like	Metalloproteases ("zincins"), catalytic domain	9	2
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	9	7
RING/U-box	FYVE/PHD zinc finger	9	6
P-loop containing nucleoside triphosphate hydrolases	Calponin-homology domain, CH-domain	9	2
(Trans)glycosidases	Protein kinase-like (PK-like)	9	3
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	9	3
(Trans)glycosidases	Ricin B-like lectins	9	3
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	9	2
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	9	3
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	9	3
HIT/MYND zinc finger-like	SET domain	9	4
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	9	2
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	3
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	9	4
L domain-like	Outer arm dynein light chain 1	8	6
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	8	4
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	8	2
GST C-terminal domain-like	GST C-terminal domain-like	8	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	8	3
E set domains	Glycosyl hydrolase domain	8	4
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	8	4
vWA-like	Helical domain of Sec23/24	8	4
FYVE/PHD zinc finger	SET domain	8	5
P-loop containing nucleoside triphosphate hydrolases	Mannose-binding lectins	8	4
PH domain-like	Oxysterol-binding protein-like	8	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	8	3
vWA-like	beta-sandwich domain of Sec23/24	8	4
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	8	4
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	8	5
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	8	4
EF-hand	Riboflavin synthase domain-like	8	2
Adenine nucleotide alpha hydrolases-like	RING/U-box	8	2
ADC-like	Cdc48 domain 2-like	8	3
L9 N-domain-like	Ribonuclease H-like	8	1
Kelch motif	Kelch motif	8	4
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	8	4
ARM repeat	Hect, E3 ligase catalytic domain	8	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	8	4
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	8	2
Cysteine proteinases	Granulin repeat	8	3
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	8	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	8	6
Amine oxidase N-terminal region	Amine oxidase catalytic domain	8	4
Periplasmic binding protein-like II	ACT-like	8	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	8	4
Zn-finger domain of Sec23/24	vWA-like	8	4
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	8	2
RNase III domain-like	RNase III domain-like	8	6
UBA-like	UBA-like	8	6
Protein kinase-like (PK-like)	WD40 repeat-like	8	5
Macro domain-like	CRAL/TRIO domain	8	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	8	3
Translation proteins	Ribosomal protein S5 domain 2-like	8	4
RING/U-box	TRAF domain-like	8	2
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	8	4
P-loop containing nucleoside triphosphate hydrolases	TGS-like	8	3
F-box domain	Tubby C-terminal domain-like	8	3
WW domain	WW domain	8	5
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	8	2
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	8	2
RNase III domain-like	dsRNA-binding domain-like	7	6
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
CheY-like	CheY-like	7	1
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	7	5
PDZ domain-like	ClpP/crotonase	7	1
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	7	1
E set domains	AMPKBI-like	7	2
Translational machinery components	L30e-like	7	3
Surp module (SWAP domain)	Surp module (SWAP domain)	7	2
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	7	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	7	2
Homeodomain-like	RING/U-box	7	3
beta-beta-alpha zinc fingers	Ribonuclease H-like	7	3
RING/U-box	RNA-binding domain, RBD	7	2
ARM repeat	TPR-like	7	2
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	7	4
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	7	4
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	7	2
Toll/Interleukin receptor TIR domain	Mannose-binding lectins	7	4
POZ domain	TAZ domain	7	2
Flavoproteins	Riboflavin synthase domain-like	7	3
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	7	2
PUA domain-like	SET domain	7	2
EF-hand	P-loop containing nucleoside triphosphate hydrolases	7	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	7	1
RING/U-box	Cysteine proteinases	7	6
SNARE fusion complex	SNARE fusion complex	7	2
ISP domain	Bet v1-like	7	3
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	7	2
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
Protein kinase-like (PK-like)	KA1-like	7	2
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	7	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	7	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	7	2
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	7	4
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	7	1
Ribosomal protein L6	Ribosomal protein L6	7	2
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	7	3
Thioredoxin-like	Cysteine-rich domain	6	5
Chromo domain-like	Homeodomain-like	6	1
Galactose oxidase, central domain	E set domains	6	2
WW domain	FF domain	6	3
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	6	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	6	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	6	2
Ribonuclease H-like	DNA/RNA polymerases	6	3
Surp module (SWAP domain)	Ubiquitin-like	6	1
FF domain	FF domain	6	3
RCC1/BLIP-II	Protein kinase-like (PK-like)	6	3
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	6	2
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	6	2
POZ domain	Pentapeptide repeat-like	6	2
ARM repeat	Tudor/PWWP/MBT	6	3
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	6	2
Protein kinase-like (PK-like)	Ankyrin repeat	6	2
E set domains	P-loop containing nucleoside triphosphate hydrolases	6	2
Rudiment single hybrid motif	Single hybrid motif	6	2
Homeodomain-like	FAD/NAD(P)-binding domain	6	2
Initiation factor IF2/eIF5b, domain 3	Translation proteins	6	2
PH domain-like	RCC1/BLIP-II	6	1
Class II aaRS ABD-related	C-terminal domain of ProRS	6	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	6	3
TPR-like	CAD & PB1 domains	6	4
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	2
Translation proteins	ThrRS/AlaRS common domain	6	3
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	6	4
E set domains	Ankyrin repeat	6	2
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	6	1
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	6	4
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	2
ARM repeat	Clathrin adaptor appendage domain	6	4
Aconitase iron-sulfur domain	LeuD/IlvD-like	6	2
HIT/MYND zinc finger-like	Cysteine proteinases	6	2
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	6	1
Ubiquitin-like	BAG domain	6	2
RCC1/BLIP-II	FYVE/PHD zinc finger	6	1
t-snare proteins	SNARE fusion complex	6	3
YrdC/RibB	RibA-like	6	3
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	6	2
POZ domain	POZ domain	6	4
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	6	2
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	6	4
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	6	2
RNA-binding domain, RBD	PABC (PABP) domain	6	4
HD-domain/PDEase-like	Nucleotidyltransferase	6	5
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	6	1
Trigger factor ribosome-binding domain	FKBP-like	6	2
DAK1/DegV-like	DhaL-like	6	3
PreATP-grasp domain	Single hybrid motif	6	2
Homeodomain-like	FAD-linked reductases, C-terminal domain	6	2
CBS-domain pair	CAD & PB1 domains	5	3
POZ domain	TPR-like	5	3
HAD-like	dsRNA-binding domain-like	5	2
SWIB/MDM2 domain	Plus3-like	5	5
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	5	3
Translation proteins	Translation proteins	5	1
UBA-like	XPC-binding domain	5	3
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	5	3
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	5	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	5	4
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	5	2
Tudor/PWWP/MBT	SET domain	5	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	5	3
BAR/IMD domain-like	SH3-domain	5	1
Carbamate kinase-like	ACT-like	5	3
PLP-dependent transferases	PLP-dependent transferases	5	4
PA domain	Zn-dependent exopeptidases	5	3
Ubiquitin-like	Zn-binding ribosomal proteins	5	1
ARID-like	HMG-box	5	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	5	3
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	5	2
L domain-like	WD40 repeat-like	5	5
(Phosphotyrosine protein) phosphatases II	E set domains	5	2
Ubiquitin-like	XPC-binding domain	5	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	5	3
NAD(P)-binding Rossmann-fold domains	Galactose-binding domain-like	5	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	5	1
Actin-crosslinking proteins	Actin-crosslinking proteins	5	1
Rhomboid-like	UBA-like	5	2
PYP-like sensor domain (PAS domain)	GAF domain-like	5	2
SPOC domain-like	C-terminal domain of Ku80	5	2
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	2
USP8 N-terminal domain-like	JAB1/MPN domain	5	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	1
Acetyl-CoA synthetase-like	Protein kinase-like (PK-like)	5	1
F-box domain	WD40 repeat-like	5	2
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	5	2
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	5	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	5	2
PP2C-like	Protein kinase-like (PK-like)	5	3
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	1
Tudor/PWWP/MBT	FYVE/PHD zinc finger	5	3
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	5	3
DNA-binding domain	DNA-binding pseudobarrel domain	5	3
GAF domain-like	GAF domain-like	5	2
CCCH zinc finger	RING/U-box	5	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	5	1
Sec7 domain	ARM repeat	5	4
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	5	1
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	5	2
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	5	4
BEACH domain	WD40 repeat-like	5	4
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	5	1
Ankyrin repeat	RING/U-box	5	2
PH domain-like	BEACH domain	5	4
Zinc beta-ribbon	Cyclin-like	5	2
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	5	2
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	5	3
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	5	3
Ribonuclease H-like	HRDC-like	5	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	5	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	5	4
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	4	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	4	1
ClpP/crotonase	ClpP/crotonase	4	3
CAD & PB1 domains	RING/U-box	4	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	4	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	4	1
Actin-crosslinking proteins	(Trans)glycosidases	4	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	4	4
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	4	1
Ubiquitin-like	PUG domain-like	4	2
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	4	4
Clathrin heavy-chain terminal domain	ARM repeat	4	1
HAD-like	BRCT domain	4	2
Cytidine deaminase-like	Dihydrofolate reductase-like	4	2
EF-hand	Mitochondrial carrier	4	2
UBA-like	P-loop containing nucleoside triphosphate hydrolases	4	2
RING/U-box	Ran binding protein zinc finger-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	4	2
SET domain	Formin homology 2 domain (FH2 domain)	4	2
PH domain-like	WD40 repeat-like	4	3
RING/U-box	UBA-like	4	2
FKBP-like	Triger factor/SurA peptide-binding domain-like	4	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	4	1
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	4	2
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	4	1
PH domain-like	Bet v1-like	4	1
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	4
PA domain	Transferrin receptor-like dimerisation domain	4	2
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	4	3
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	4	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	4	2
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	4	4
SWIB/MDM2 domain	SWIB/MDM2 domain	4	2
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	4	2
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	4	3
Dom34/Pelota N-terminal domain-like	Translational machinery components	4	1
PRTase-like	PRTase-like	4	2
EF-hand	Calponin-homology domain, CH-domain	4	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	4	2
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	4	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
NAD(P)-binding Rossmann-fold domains	Citrate synthase	4	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	4	2
PAZ domain	RNase III domain-like	4	4
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	4	4
Thioredoxin-like	TPR-like	4	3
Carbamate kinase-like	ALDH-like	4	1
ARM repeat	Subdomain of clathrin and coatomer appendage domain	4	3
Chaperone J-domain	4Fe-4S ferredoxins	4	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	4	1
WD40 repeat-like	SNARE fusion complex	4	3
vWA-like	SPOC domain-like	4	3
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	4	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	4	2
Acetyl-CoA synthetase-like	ACP-like	4	2
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	4	3
Ubiquitin-like	Protein kinase-like (PK-like)	4	2
RING/U-box	PUA domain-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	4	3
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	4	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	4	2
Chitinase insertion domain	Protein kinase-like (PK-like)	4	1
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	4	2
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	4	4
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	4	3
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	4	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	4	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	4	2
GST C-terminal domain-like	eEF-1beta-like	4	2
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	4
FAD/NAD(P)-binding domain	EF-hand	4	3
Enolase N-terminal domain-like	Enolase C-terminal domain-like	4	2
F-box domain	HCP-like	4	3
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
Dom34/Pelota N-terminal domain-like	L30e-like	4	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	4	2
PriA/YqbF domain	GINS helical bundle-like	4	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	4	4
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	4	2
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	4	2
TPR-like	Chaperone J-domain	4	3
Arp2/3 complex subunits	Arp2/3 complex subunits	4	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
ARID-like	FYVE/PHD zinc finger	4	2
GAF domain-like	CheY-like	4	3
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	4	3
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	4	2
Ubiquitin-like	Acid proteases	4	2
Taf5 N-terminal domain-like	WD40 repeat-like	4	1
Thioredoxin-like	Ubiquitin-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	4	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	4	2
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	4	2
Glutamine synthetase/guanido kinase	GatB/YqeY motif	4	2
(Trans)glycosidases	(Trans)glycosidases	4	3
P-loop containing nucleoside triphosphate hydrolases	vWA-like	4	1
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	4	2
SMAD/FHA domain	Phospholipase D/nuclease	4	3
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	4	1
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	3
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	3	1
TATA-box binding protein-like	TATA-box binding protein-like	3	1
SWIB/MDM2 domain	GYF domain	3	3
Galactose oxidase, central domain	Galactose oxidase, central domain	3	1
Tricorn protease domain 2	WD40 repeat-like	3	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	3	1
TolB, C-terminal domain	Quinoprotein alcohol dehydrogenase-like	3	1
Cytochrome P450	Cytochrome P450	3	3
PUA domain-like	Nucleotidylyl transferase	3	1
WD40 repeat-like	DNase I-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	3	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	3	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	3	1
Plus3-like	GYF domain	3	3
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	1
ARM repeat	UBA-like	3	2
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	3	2
L30e-like	alpha/beta knot	3	1
Cytochrome f, large domain	Rudiment single hybrid motif	3	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	3	2
Kelch motif	Metallo-dependent phosphatases	3	1
Ubiquitin-like	Cap-Gly domain	3	2
Saposin	Saposin	3	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	3	3
ACP-like	Heme-dependent catalase-like	3	1
ARM repeat	PH domain-like	3	3
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	3	2
SWIB/MDM2 domain	eIF1-like	3	1
Dcp2 domain-like	Nudix	3	2
RNI-like	Glutathione synthetase ATP-binding domain-like	3	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	3	3
PAZ domain	dsRNA-binding domain-like	3	3
Nucleotidylyl transferase	Nucleotidylyl transferase	3	1
LEA14-like	LEA14-like	3	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	3	3
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	3	2
F-box domain	Actin-like ATPase domain	3	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	3	2
HIT-like	HIT-like	3	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
Six-hairpin glycosidases	AbfB domain	3	2
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	3	2
Cystatin/monellin	Cystatin/monellin	3	1
Ubiquitin-like	HAD-like	3	1
Actin-like ATPase domain	AF1104-like	3	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	3	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
HisI-like	all-alpha NTP pyrophosphatases	3	2
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	3	2
FYSH domain	Hypothetical protein AF0491, middle domain	3	1
BSD domain-like	BSD domain-like	3	1
F-box domain	SMI1/KNR4-like	3	1
ARID-like	HSP20-like chaperones	3	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	3	1
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	3	2
TPR-like	PUA domain-like	3	2
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	3	1
SAP domain	FYVE/PHD zinc finger	3	2
Tudor/PWWP/MBT	Tudor/PWWP/MBT	3	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	3	1
PH domain-like	Phospholipase D/nuclease	3	2
PUA domain-like	SWIB/MDM2 domain	3	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	3	2
F-box domain	ApaG-like	3	1
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	3	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
Protein kinase-like (PK-like)	UBA-like	3	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	3	3
Cysteine proteinases	Formin homology 2 domain (FH2 domain)	3	1
Double Clp-N motif	Double Clp-N motif	3	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	3	3
Aspartate/glutamate racemase	Aspartate/glutamate racemase	3	1
Ricin B-like lectins	Glycosyl hydrolase domain	3	1
Trypsin-like serine proteases	Trypsin-like serine proteases	3	2
Sec63 N-terminal domain-like	E set domains	3	2
Cysteine proteinases	Galactose-binding domain-like	3	3
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	3	1
YjgF-like	YjgF-like	3	3
WD40 repeat-like	Nucleoporin domain	3	3
Methylglyoxal synthase-like	Cytidine deaminase-like	3	2
HAD-like	NHL repeat	3	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	3	1
CAD & PB1 domains	UBA-like	3	1
Thioredoxin-like	NHL repeat	3	2
PH domain-like	BSD domain-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Outer arm dynein light chain 1	3	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	3	2
NTF2-like	Probable bacterial effector-binding domain	3	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	3	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	3
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	3	3
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	3	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	3	1
TPR-like	HSP20-like chaperones	3	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	3	2
beta-sandwich domain of Sec23/24	RNA-binding domain, RBD	3	3
ACP-like	Trimeric LpxA-like enzymes	3	1
PAH2 domain	PAH2 domain	3	1
TolB, C-terminal domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
SMI1/KNR4-like	ApaG-like	3	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	3	2
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	3	1
TPR-like	SET domain	3	3
GroEL apical domain-like	SAICAR synthase-like	3	2
PUA domain-like	eIF1-like	3	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	3	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	3	1
WGR domain-like	ADP-ribosylation	3	3
UBC-like	RING/U-box	3	2
FAD/NAD(P)-binding domain	ACP-like	3	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	3	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	3	2
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	3	2
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	3	1
FYVE/PHD zinc finger	Homeodomain-like	3	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	3	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	3	2
Staphylococcal nuclease	Staphylococcal nuclease	3	2
PreATP-grasp domain	PreATP-grasp domain	3	2
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	3	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	3	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
HAD-like	Thioredoxin-like	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	2
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	3	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	3	3
UBA-like	Hect, E3 ligase catalytic domain	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	1
Amidase signature (AS) enzymes	TPR-like	3	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	3	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	3	2
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
UBA-like	KA1-like	3	1
PLC-like phosphodiesterases	PLC-like phosphodiesterases	3	2
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	3	1
FYSH domain	beta-beta-alpha zinc fingers	3	1
Ubiquitin-like	Cysteine proteinases	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	3	1
SBT domain	Ankyrin repeat	3	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	3	2
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	3	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	3	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	1
L domain-like	Ubiquitin-like	3	2
Restriction endonuclease-like	RuvA domain 2-like	3	2
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	3	1
DUSP-like	Cysteine proteinases	3	2
Granulin repeat	Formin homology 2 domain (FH2 domain)	3	1
PurM N-terminal domain-like	PurM C-terminal domain-like	3	2
cAMP-binding domain-like	cAMP-binding domain-like	3	2
HAD-like	Riboflavin kinase-like	3	1
Chaperone J-domain	RNA-binding domain, RBD	3	2
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	2	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	2
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	2	2
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
TPR-like	RNA-binding domain, RBD	2	2
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	2	1
DNase I-like	EF-hand	2	2
BAR/IMD domain-like	PH domain-like	2	2
HCP-like	Homing endonucleases	2	1
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	2	1
alpha-D-mannose-specific plant lectins	EGF/Laminin	2	2
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	2	1
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
Ran binding protein zinc finger-like	Translation proteins	2	1
PapD-like	Ankyrin repeat	2	2
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	2	1
POZ domain	Galactose-binding domain-like	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	2
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	1
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	2	1
Putative cyclase	Putative cyclase	2	1
Nucleotidylyl transferase	Tropomyosin	2	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	2	1
F-box domain	Clavaminate synthase-like	2	2
vWA-like	C-terminal domain of Ku80	2	1
Putative DNA-binding domain	Putative DNA-binding domain	2	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Urease, gamma-subunit	Metallo-dependent hydrolases	2	2
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	2	1
BAR/IMD domain-like	Ankyrin repeat	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
Concanavalin A-like lectins/glucanases	PH domain-like	2	2
Concanavalin A-like lectins/glucanases	Cysteine proteinases	2	1
PUA domain-like	Ribosomal protein S5 domain 2-like	2	2
Urease, gamma-subunit	Urease, beta-subunit	2	2
Urease, beta-subunit	Metallo-dependent hydrolases	2	2
CCCH zinc finger	HIT-like	2	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	2	2
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	2	1
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	2	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	1
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
MoeA N-terminal region -like	MoeA C-terminal domain-like	2	2
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	2	1
Cyclophilin-like	TPR-like	2	1
RNA-binding domain, RBD	WW domain	2	2
BRCT domain	WGR domain-like	2	2
PDZ domain-like	PDZ domain-like	2	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
YjeF N-terminal domain-like	FMN-binding split barrel	2	2
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
Cullin homology domain	Cullin homology domain	2	1
Second domain of FERM	PH domain-like	2	1
Cyclophilin-like	Retrovirus zinc finger-like domains	2	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	2	1
Tropomyosin	Tropomyosin	2	2
ARM repeat	SH3-domain	2	1
Nucleoside hydrolase	Nucleoside hydrolase	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Formyltransferase	FMT C-terminal domain-like	2	1
HAD-like	NTF2-like	2	2
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	2	1
FAD/NAD(P)-binding domain	SMAD/FHA domain	2	1
Pre-PUA domain	PUA domain-like	2	1
Trimeric LpxA-like enzymes	ARM repeat	2	1
Nucleotide-binding domain	FAD/NAD(P)-binding domain	2	1
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	2
Acid proteases	UBA-like	2	2
EF-hand	RING/U-box	2	2
Thioredoxin-like	FAD-dependent thiol oxidase	2	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	2	1
PheT/TilS domain	Class II aaRS and biotin synthetases	2	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	2	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	2	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
ARM repeat	BEACH domain	2	2
RING/U-box	Cyclophilin-like	2	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	2	2
ISP transmembrane anchor	ISP domain	2	1
E set domains	CBS-domain pair	2	1
PRP4-like	WD40 repeat-like	2	1
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
Clavaminate synthase-like	RING/U-box	2	1
Protein prenylyltransferase	L domain-like	2	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	2	2
Tropomyosin	Apolipoprotein A-I	2	2
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	2	1
Kix domain of CBP (creb binding protein)	F-box domain	2	1
GST C-terminal domain-like	Nucleic acid-binding proteins	2	1
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	2	1
DNA clamp	DNA clamp	2	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
RING/U-box	Formin homology 2 domain (FH2 domain)	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
Enolase N-terminal domain-like	alpha/beta-Hydrolases	2	1
Carbamate kinase-like	Carbamate kinase-like	2	2
TPR-like	HIT/MYND zinc finger-like	2	2
Histone-fold	ARM repeat	2	1
"Winged helix" DNA-binding domain	E set domains	2	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	2	1
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	2	2
Dihydrofolate reductase-like	YbiA-like	2	1
L9 N-domain-like	Ribosomal protein L9 C-domain	2	1
Nucleotidyltransferase	EF-hand	2	1
Class II aaRS and biotin synthetases	Translation proteins	2	2
Alpha-L RNA-binding motif	Pseudouridine synthase	2	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	2	1
Ankyrin repeat	TPR-like	2	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
WD40 repeat-like	Tricorn protease N-terminal domain	2	1
FYVE/PHD zinc finger	Plus3-like	2	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	2	2
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
Thioredoxin-like	"Winged helix" DNA-binding domain	2	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	2
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	2	1
F-box domain	HIT/MYND zinc finger-like	2	2
Nucleotide-diphospho-sugar transferases	ARM repeat	2	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	1
RNI-like	Outer arm dynein light chain 1	2	2
HCP-like	HIT/MYND zinc finger-like	2	2
HD-domain/PDEase-like	EF-hand	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Oxidoreductase molybdopterin-binding domain	E set domains	2	2
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	2	2
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	2	2
F-box domain	L domain-like	2	2
PH domain-like	Prismane protein-like	2	1
FYVE/PHD zinc finger	SWIB/MDM2 domain	2	2
PH domain-like	ArfGap/RecO-like zinc finger	2	2
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	2	2
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	2	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	2	2
Cap-Gly domain	L domain-like	2	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	2	1
TPR-like	SMR domain-like	2	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	2	1
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	1
Formin homology 2 domain (FH2 domain)	RuBisCo LSMT C-terminal, substrate-binding domain	2	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	2	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	2	1
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	2	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	2	2
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
E set domains	RNA-binding domain, RBD	2	1
AN1-like Zinc finger	AN1-like Zinc finger	2	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
RmlC-like cupins	RmlC-like cupins	2	2
ITPase-like	ITPase-like	2	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	2
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	2	2
Cytidine deaminase-like	YbiA-like	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	2
PH domain-like	Ankyrin repeat	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	2	2
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
SAP domain	RNA-binding domain, RBD	2	1
GroEL-intermediate domain like	GroEL-intermediate domain like	2	1
TATA-box binding protein-like	DNA-glycosylase	2	1
alpha-D-mannose-specific plant lectins	CBS-domain pair	2	2
Ribonuclease H-like	Ribonuclease H-like	2	2
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	2	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
PIN domain-like	Chromo domain-like	2	1
BRCT domain	ADP-ribosylation	2	2
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	2	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	1
RNA-binding domain, RBD	PWI domain	2	1
HD-domain/PDEase-like	TGS-like	2	2
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	2	2
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	2	2
PP2C-like	cAMP-binding domain-like	2	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	2	1
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
ARM repeat	"Winged helix" DNA-binding domain	2	1
RNI-like	WD40 repeat-like	2	2
Protein kinase-like (PK-like)	Activating enzymes of the ubiquitin-like proteins	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	1
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	2	1
PH domain-like	HMG-box	2	1
PX domain	BAR/IMD domain-like	2	2
Enolase C-terminal domain-like	alpha/beta-Hydrolases	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	2	1
UraD-Like	Transthyretin (synonym: prealbumin)	2	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	2	1
Thioredoxin-like	Six-hairpin glycosidases	2	2
UBA-like	Thioredoxin-like	2	1
ARM repeat	Concanavalin A-like lectins/glucanases	2	2
RNI-like	SET domain	2	1
PDZ domain-like	TPR-like	2	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Chaperone J-domain	Thioredoxin-like	2	2
Ribonuclease H-like	RING/U-box	2	2
F-box domain	SET domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	2	1
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	1
BRCT domain	post-AAA+ oligomerization domain-like	2	1
Nucleotidyltransferase	TGS-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	2
PYP-like sensor domain (PAS domain)	F-box domain	2	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Adenine nucleotide alpha hydrolases-like	YjgF-like	2	2
Second domain of FERM	Prismane protein-like	2	1
"Winged helix" DNA-binding domain	Zinc beta-ribbon	2	1
Kix domain of CBP (creb binding protein)	RNI-like	2	1
Terpenoid synthases	Terpenoid synthases	2	2
Heme oxygenase-like	HAD-like	2	2
WD40 repeat-like	Calcium-dependent phosphotriesterase	2	2
TPR-like	Metallo-dependent phosphatases	2	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	2	1
Surp module (SWAP domain)	ENTH/VHS domain	2	1
Putative DNA-binding domain	PheT/TilS domain	2	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	2	1
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
FYVE/PHD zinc finger	ARM repeat	2	1
RNA-binding domain, RBD	ENTH/VHS domain	2	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
DAK1/DegV-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
(Phosphotyrosine protein) phosphatases II	P-loop containing nucleoside triphosphate hydrolases	1	1
RNI-like	EF-hand	1	1
SSo0622-like	Kelch motif	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Aminoacid dehydrogenase-like, N-terminal domain	CBS-domain pair	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
F-box domain	Pectin lyase-like	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Ubiquitin-like	Bromodomain	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
Pseudo ankyrin repeat-like	Ankyrin repeat	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
UBA-like	PUG domain-like	1	1
WD40 repeat-like	Soluble quinoprotein glucose dehydrogenase	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
beta-sandwich domain of Sec23/24	Galactose-binding domain-like	1	1
ARID-like	Clavaminate synthase-like	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
HD-domain/PDEase-like	ACT-like	1	1
PRC-barrel domain	PRC-barrel domain	1	1
Nucleic acid-binding proteins	UBA-like	1	1
BRCT domain	PsbU/PolX domain-like	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
R3H domain	Ankyrin repeat	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cyclin-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Ubiquitin-like	Homeodomain-like	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
Starch-binding domain-like	Cna protein B-type domain	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Hypothetical protein PA1324	Starch-binding domain-like	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
SRF-like	DNase I-like	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Arabinanase/levansucrase/invertase	Arabinanase/levansucrase/invertase	1	1
EF-hand	TPR-like	1	1
Macro domain-like	HIT-like	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
RNI-like	ARM repeat	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
UBC-like	UBA-like	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
Amine oxidase catalytic domain	Amine oxidase catalytic domain	1	1
Macro domain-like	Macro domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
vWA-like	Cysteine-rich domain	1	1
DPP6 N-terminal domain-like	Protein kinase-like (PK-like)	1	1
Nucleoporin domain	Quinoprotein alcohol dehydrogenase-like	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
Smc hinge domain	Tropomyosin	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
RNA-binding domain, RBD	Formin homology 2 domain (FH2 domain)	1	1
AF0104/ALDC/Ptd012-like	L domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
TGS-like	Class II aaRS ABD-related	1	1
SAP domain	DNase I-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
Protease propeptides/inhibitors	PA domain	1	1
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	1	1
Chaperone J-domain	ARM repeat	1	1
(Phosphotyrosine protein) phosphatases II	Toll/Interleukin receptor TIR domain	1	1
SAP domain	SAP domain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
Aminopeptidase/glucanase lid domain	Aminopeptidase/glucanase lid domain	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
beta-sandwich domain of Sec23/24	Band 7/SPFH domain	1	1
SMAD/FHA domain	PP2C-like	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
PUA domain-like	PUA domain-like	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
SH2 domain	SH2 domain	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
CarD-like	TRCF domain-like	1	1
Helical scaffold and wing domains of SecA	Helical scaffold and wing domains of SecA	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
POZ domain	Actin-crosslinking proteins	1	1
Ribosomal protein S2	Nucleotide-diphospho-sugar transferases	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Ribonuclease H-like	SH2 domain	1	1
L domain-like	EF-hand	1	1
DNase I-like	DNase I-like	1	1
POZ domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
E set domains	Riboflavin synthase domain-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
SMAD/FHA domain	BRCT domain	1	1
HCP-like	Chaperone J-domain	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
TAZ domain	FYVE/PHD zinc finger	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
PDZ domain-like	Rubredoxin-like	1	1
Pectin lyase-like	Pectin lyase-like	1	1
Starch-binding domain-like	Phosphoglycerate mutase-like	1	1
Ubiquitin-like	TPR-like	1	1
ARM repeat	POZ domain	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Mitochondrial carrier	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
Cytochrome b559 subunits	Cytochrome b559 subunits	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
Putative isomerase YbhE	RING/U-box	1	1
DNA-binding domain	Bromodomain	1	1
BRCT domain	DNA/RNA polymerases	1	1
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	1	1
Cysteine proteinases	UBA-like	1	1
Protein kinase-like (PK-like)	PH domain-like	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
SufE/NifU	NadA-like	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
F-box domain	NTF2-like	1	1
Chromo domain-like	Ankyrin repeat	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
NAD(P)-linked oxidoreductase	NAD(P)-linked oxidoreductase	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
NAD(P)-binding Rossmann-fold domains	Mitochondrial carrier	1	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
MFS general substrate transporter	PUA domain-like	1	1
Lipoxigenase	Lipoxigenase	1	1
Amine oxidase catalytic domain	ARM repeat	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein transmembrane domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
alpha-D-mannose-specific plant lectins	DPP6 N-terminal domain-like	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
Chaperone J-domain	CSL zinc finger	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
F-box domain	Tricorn protease domain 2	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
HMG-box	HMG-box	1	1
Plus3-like	CCCH zinc finger	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Tex N-terminal region-like	SH2 domain	1	1
SWIB/MDM2 domain	CCCH zinc finger	1	1
alpha-D-mannose-specific plant lectins	Quinoprotein alcohol dehydrogenase-like	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
WW domain	P-loop containing nucleoside triphosphate hydrolases	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
L domain-like	Cyclin-like	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Protein kinase-like (PK-like)	Formin homology 2 domain (FH2 domain)	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
E set domains	E set domains	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
YgbK-like	Aldolase	1	1
BRCT domain	Nucleotidyltransferase	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
BRCT domain	FYVE/PHD zinc finger	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
Nucleotidyltransferase	ACT-like	1	1
Ribosomal protein L22	Ribosomal protein S3 C-terminal domain	1	1
L domain-like	ARM repeat	1	1
Single hybrid motif	Single hybrid motif	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
SPOC domain-like	SAP domain	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
Calcium ATPase, transduction domain A	ARM repeat	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
Toll/Interleukin receptor TIR domain	Homeodomain-like	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	P-loop containing nucleoside triphosphate hydrolases	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
GYF domain	SET domain	1	1
FYVE/PHD zinc finger	GYF domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Toll/Interleukin receptor TIR domain	1	1
SAP domain	ADP-ribosylation	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Translation proteins	PRC-barrel domain	1	1
Ran binding protein zinc finger-like	DNase I-like	1	1
NAD(P)-binding Rossmann-fold domains	CBS-domain pair	1	1
Six-hairpin glycosidases	Carbohydrate-binding domain	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
TPR-like	RNI-like	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
DNA-glycosylase	Nudix	1	1
TAZ domain	RING/U-box	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
Ammonium transporter	Ammonium transporter	1	1
F-box domain	Putative isomerase YbhE	1	1
F-box domain	YWTD domain	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
DAK1/DegV-like	Ribosomal protein S5 domain 2-like	1	1
Acyl-CoA binding protein	Kelch motif	1	1
Hypothetical protein PA1324	Cna protein B-type domain	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
Quinoprotein alcohol dehydrogenase-like	SNARE fusion complex	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
DhaL-like	DhaL-like	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	1	1
POZ domain	WD40 repeat-like	1	1
Protein kinase-like (PK-like)	PLP-dependent transferases	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	"Winged helix" DNA-binding domain	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
PurS-like	PurM N-terminal domain-like	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
beta-sandwich domain of Sec23/24	NAD(P)-binding Rossmann-fold domains	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Amine oxidase N-terminal region	ARM repeat	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	1	1
CinA-like	Nucleotidylyl transferase	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
C-terminal UvrC-binding domain of UvrB	ApaG-like	1	1
L domain-like	HMA, heavy metal-associated domain	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
GYF domain	RNA-binding domain, RBD	1	1
ACT-like	Formyltransferase	1	1
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Hypothetical protein PA1324	Carboxypeptidase regulatory domain-like	1	1
Quinoprotein alcohol dehydrogenase-like	Calcium-dependent phosphotriesterase	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
vWA-like	SAP domain	1	1
PHL pollen allergen	PHL pollen allergen	1	1
Carboxypeptidase regulatory domain-like	Cna protein B-type domain	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
SAP domain	WGR domain-like	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
GAT-like domain	GAT-like domain	1	1
Formin homology 2 domain (FH2 domain)	P-loop containing nucleoside triphosphate hydrolases	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	S13-like H2TH domain	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Pseudouridine synthase	PUA domain-like	1	1
Skp1 dimerisation domain-like	L domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PABC (PABP) domain	1	1
alpha/beta-Hydrolases	Formin homology 2 domain (FH2 domain)	1	1
Single hybrid motif	ClpP/crotonase	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
Cyclophilin-like	RNA-binding domain, RBD	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Chaperone J-domain	Homeodomain-like	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
Tudor/PWWP/MBT	RNA-binding domain, RBD	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
Lysozyme-like	Lysozyme-like	1	1
Clavaminate synthase-like	Clavaminate synthase-like	1	1
L domain-like	FabD/lysophospholipase-like	1	1
SufE/NifU	BolA-like	1	1
alpha-D-mannose-specific plant lectins	Clc chloride channel	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein cytoplasmic domain-like	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Photosystem I reaction center subunit XI, PsaL	Photosystem I reaction center subunit XI, PsaL	1	1
Formin homology 2 domain (FH2 domain)	TPR-like	1	1
Thioredoxin-like	VC0467-like	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
Flavoproteins	Radical SAM enzymes	1	1
Ubiquitin-like	Galactose-binding domain-like	1	1
beta-sandwich domain of Sec23/24	P-loop containing nucleoside triphosphate hydrolases	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
PUA domain-like	alpha/beta knot	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
WD40 repeat-like	TPR-like	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
N-terminal domain of the delta subunit of the F1F0-ATP synthase	N-terminal domain of the delta subunit of the F1F0-ATP synthase	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
PH domain-like	GTPase activation domain, GAP	1	1
RuvA domain 2-like	SH2 domain	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
SAP domain	CCCH zinc finger	1	1
DNA-binding domain	FYVE/PHD zinc finger	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
Chaperone J-domain	E set domains	1	1
UBA-like	post-AAA+ oligomerization domain-like	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
DPP6 N-terminal domain-like	DPP6 N-terminal domain-like	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Bromodomain	FYVE/PHD zinc finger	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
Ankyrin repeat	Subtilisin-like	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
FAH	FAH	1	1
AN1-like Zinc finger	beta-beta-alpha zinc fingers	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
GYF domain	CCCH zinc finger	1	1
Kix domain of CBP (creb binding protein)	Kix domain of CBP (creb binding protein)	1	1
L domain-like	Calcium-dependent phosphotriesterase	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	NAD(P)-binding Rossmann-fold domains	1	1
Skp1 dimerisation domain-like	Actin-crosslinking proteins	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
TAZ domain	TAZ domain	1	1
FYVE/PHD zinc finger	TPR-like	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
TGS-like	ACT-like	1	1
WD40 repeat-like	Bromodomain	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
S13-like H2TH domain	Ribosomal protein S5 domain 2-like	1	1
ssDNA-binding transcriptional regulator domain	Retrovirus zinc finger-like domains	1	1
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
PurS-like	PurM C-terminal domain-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1