Domain combination pairs in Eucalyptus grandis v201

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1443 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
L domain-like	L domain-like	694	127
P-loop containing nucleoside triphosphate hydrolases	L domain-like	639	99
L domain-like	Protein kinase-like (PK-like)	636	44
L domain-like	RNI-like	390	108
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	338	68
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	308	14
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	306	65
GroES-like	NAD(P)-binding Rossmann-fold domains	206	8
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	204	41
Toll/Interleukin receptor TIR domain	L domain-like	198	46
RNI-like	Protein kinase-like (PK-like)	179	31
Toll/Interleukin receptor TIR domain	"Winged helix" DNA-binding domain	146	25
Thioredoxin-like	GST C-terminal domain-like	138	7
"Winged helix" DNA-binding domain	L domain-like	132	29
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	131	5
Cupredoxins	Cupredoxins	128	14
RNA-binding domain, RBD	RNA-binding domain, RBD	124	28
P-loop containing nucleoside triphosphate hydrolases	ABC transporter transmembrane region	111	19
RNI-like	RNI-like	109	49
HAD-like	Calcium ATPase, transmembrane domain M	106	19
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	104	19
Calcium ATPase, transduction domain A	HAD-like	99	15
F-box domain	RNI-like	95	10
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	89	5
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	88	2
ABC transporter transmembrane region	ABC transporter transmembrane region	87	11
TPR-like	TPR-like	86	21
Actin-like ATPase domain	Actin-like ATPase domain	73	17
P-loop containing nucleoside triphosphate hydrolases	RNI-like	73	39
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	72	13
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	69	11
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	69	10
RING/U-box	ARM repeat	68	10
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	66	7
ARM repeat	ARM repeat	65	26
Periplasmic binding protein-like I	Periplasmic binding protein-like II	64	7
Thiolase-like	Thiolase-like	55	2
Voltage-gated potassium channels	cAMP-binding domain-like	54	6
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	54	10
(Trans)glycosidases	Galactose-binding domain-like	54	11
(Trans)glycosidases	Glycosyl hydrolase domain	53	10
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	53	6
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	51	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	48	7
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	48	7
Protein kinase-like (PK-like)	EF-hand	48	2
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	47	7
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	43	3
RING/U-box	RING/U-box	43	21
Barwin-like endoglucanases	PHL pollen allergen	43	2
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	40	4
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	40	14
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	38	7
TRAF domain-like	TRAF domain-like	37	4
Cyclin-like	Cyclin-like	37	7
Homeodomain-like	Homeodomain-like	36	11
GroES-like	GroES-like	36	5
ENTH/VHS domain	GAT-like domain	35	5
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	35	7
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	34	10
CCCH zinc finger	CCCH zinc finger	32	20
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	31	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	31	6
Galactose-binding domain-like	Galactose-binding domain-like	31	4
ACT-like	ACT-like	30	11
F-box domain	Galactose oxidase, central domain	30	3
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	30	8
Thioredoxin-like	Thioredoxin-like	29	16
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	29	7
WD40 repeat-like	WD40 repeat-like	29	15
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	29	14
Cullin repeat-like	Cullin homology domain	28	3
SNARE-like	SNARE fusion complex	28	3
Cullin homology domain	"Winged helix" DNA-binding domain	28	4
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	28	7
Phospholipase D/nuclease	Phospholipase D/nuclease	28	12
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	27	13
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	27	2
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	26	5
Galactose mutarotase-like	(Trans)glycosidases	26	5
ARM repeat	Protein kinase-like (PK-like)	26	13
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	26	4
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	26	3
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	25	1
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	25	5
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	25	5
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	25	6
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	24	3
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	24	4
Cullin repeat-like	"Winged helix" DNA-binding domain	24	2
YhbY-like	YhbY-like	24	8
DNA-binding domain	DNA-binding domain	24	4
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	24	8
WRKY DNA-binding domain	WRKY DNA-binding domain	23	2
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	23	11
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	23	10
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	22	3
Nucleic acid-binding proteins	Nucleic acid-binding proteins	22	16
Homeodomain-like	Bet v1-like	22	3
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	22	4
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	22	8
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	22	2
Trypsin-like serine proteases	PDZ domain-like	22	5
F-box domain	Kelch motif	21	3
DNA-binding pseudobarrel domain	CAD & PB1 domains	21	4
Ankyrin repeat	Ankyrin repeat	21	5
Galactose mutarotase-like	Glycosyl hydrolase domain	21	2
Nucleotide-diphospho-sugar transferases	RING/U-box	21	3
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	21	3
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	21	11
PAZ domain	Ribonuclease H-like	21	2
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	21	7
Bet v1-like	Bet v1-like	20	6
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	20	6
Mannose-binding lectins	Mannose-binding lectins	20	12
(Trans)glycosidases	Chitinase insertion domain	20	3
Ubiquitin-like	UBA-like	20	8
CHY zinc finger-like	Zinc hairpin stack	20	5
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	20	3
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	20	3
GroEL-intermediate domain like	GroEL apical domain-like	20	3
GroEL equatorial domain-like	GroEL apical domain-like	20	3
GroEL equatorial domain-like	GroEL-intermediate domain like	20	3
CHY zinc finger-like	RING/U-box	19	4
Zinc hairpin stack	RING/U-box	19	4
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	19	3
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	19	4
Protein kinase-like (PK-like)	RING/U-box	18	4
Clc chloride channel	CBS-domain pair	18	6
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	18	2
Voltage-gated potassium channels	EF-hand	18	8
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	18	9
POZ domain	Skp1 dimerisation domain-like	18	4
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	18	2
Toll/Interleukin receptor TIR domain	RNI-like	18	14
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	18	9
PK beta-barrel domain-like	PK C-terminal domain-like	18	2
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	18	3
TPR-like	HCP-like	18	7
vWA-like	RING/U-box	18	3
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	17	4
FYVE/PHD zinc finger	FYVE/PHD zinc finger	17	10
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	17	4
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	17	2
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	17	6
EF-G C-terminal domain-like	EF-G C-terminal domain-like	16	7
UROD/MetE-like	UROD/MetE-like	16	2
Translation proteins SH3-like domain	Nucleic acid-binding proteins	16	5
dsRNA-binding domain-like	dsRNA-binding domain-like	16	9
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	16	6
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	16	4
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	16	3
Voltage-gated potassium channels	Voltage-gated potassium channels	16	7
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	16	2
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	16	4
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	16	3
Cysteine-rich domain	Cysteine-rich domain	16	11
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	16	7
Subtilisin-like	PA domain	16	4
CCCH zinc finger	WD40 repeat-like	16	1
Translation proteins	EF-G C-terminal domain-like	16	7
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	15	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	15	5
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	15	3
CCCH zinc finger	RNA-binding domain, RBD	15	4
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	15	9
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	15	3
cAMP-binding domain-like	Ankyrin repeat	15	2
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	15	5
Voltage-gated potassium channels	Ankyrin repeat	15	2
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	15	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	15	5
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	15	2
NAD(P)-binding Rossmann-fold domains	Aldolase	15	2
Ubiquitin-like	Ubiquitin-like	15	6
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	14	5
ARM repeat	WD40 repeat-like	14	10
ENT-like	Tudor/PWWP/MBT	14	2
Plant lectins/antimicrobial peptides	Lysozyme-like	14	1
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	14	2
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	14	4
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	14	5
NAD(P)-binding Rossmann-fold domains	ACT-like	14	4
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	14	5
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	14	3
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	14	1
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	14	5
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	14	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	14	5
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	13	6
EF-hand	EF-hand	13	5
NTF2-like	RNA-binding domain, RBD	13	2
Chromo domain-like	Chromo domain-like	13	5
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	13	6
PH domain-like	FYVE/PHD zinc finger	13	2
FAS1 domain	FAS1 domain	13	4
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	13	7
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	13	6
Growth factor receptor domain	Protein kinase-like (PK-like)	13	2
HCP-like	HCP-like	13	7
FKBP-like	TPR-like	13	3
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	12	2
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	12	4
EF-hand	PLC-like phosphodiesterases	12	3
Serine metabolism enzymes domain	ACT-like	12	3
RCC1/BLIP-II	RCC1/BLIP-II	12	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	12	3
CBS-domain pair	CBS-domain pair	12	8
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	12	6
Acid proteases	Saposin	12	3
Galactose-binding domain-like	Galactose mutarotase-like	12	3
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	12	4
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	12	3
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	12	5
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	12	6
"Winged helix" DNA-binding domain	RNI-like	12	10
POZ domain	TRAF domain-like	12	3
EGF/Laminin	Protein kinase-like (PK-like)	12	4
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	12	7
PreATP-grasp domain	Rudiment single hybrid motif	12	5
Single hybrid motif	CoA-dependent acyltransferases	12	5
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	12	2
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	12	2
CAD & PB1 domains	Protein kinase-like (PK-like)	12	2
Starch-binding domain-like	Galactose-binding domain-like	11	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	11	8
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	11	5
ACT-like	Protein kinase-like (PK-like)	11	1
TRAF domain-like	Cysteine proteinases	11	2
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	11	6
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	11	5
RING/U-box	WD40 repeat-like	11	8
Homeodomain-like	"Winged helix" DNA-binding domain	11	3
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	11	6
Galactose mutarotase-like	Starch-binding domain-like	11	2
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	11	2
BRCT domain	BRCT domain	11	5
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	11	8
POZ domain	Ankyrin repeat	11	5
Tricorn protease domain 2	alpha/beta-Hydrolases	11	2
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	10	5
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	10	4
LysM domain	Protein kinase-like (PK-like)	10	3
E set domains	(Trans)glycosidases	10	6
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	10	7
Amine oxidase N-terminal region	Amine oxidase N-terminal region	10	4
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	10	4
HMA, heavy metal-associated domain	HAD-like	10	7
Cysteine proteinases	Sec-C motif	10	5
PA domain	RING/U-box	10	2
MFS general substrate transporter	MFS general substrate transporter	10	2
Protease propeptides/inhibitors	Subtilisin-like	10	3
TPR-like	Protein kinase-like (PK-like)	10	3
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	10	4
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	10	6
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	10	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	10	8
FYVE/PHD zinc finger	RING/U-box	9	6
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	9	7
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	9	3
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	9	4
(Trans)glycosidases	Protein kinase-like (PK-like)	9	3
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	9	5
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	9	2
FKBP-like	FKBP-like	9	2
TPR-like	RING/U-box	9	4
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	9	3
CheY-like	Homeodomain-like	9	2
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	3
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	9	2
HIT/MYND zinc finger-like	SET domain	9	4
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	9	2
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	9	3
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	9	3
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	9	2
PGBD-like	Metalloproteases ("zincins"), catalytic domain	9	2
Actin depolymerizing proteins	Actin depolymerizing proteins	9	5
(Trans)glycosidases	Ricin B-like lectins	9	3
L9 N-domain-like	Ribonuclease H-like	8	1
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	8	2
Macro domain-like	CRAL/TRIO domain	8	2
Amine oxidase N-terminal region	Amine oxidase catalytic domain	8	4
Kelch motif	Kelch motif	8	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	8	4
P-loop containing nucleoside triphosphate hydrolases	Mannose-binding lectins	8	4
L domain-like	Outer arm dynein light chain 1	8	6
RNase III domain-like	RNase III domain-like	8	6
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	8	4
ARM repeat	Hect, E3 ligase catalytic domain	8	3
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	8	3
Protein kinase-like (PK-like)	WD40 repeat-like	8	5
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	8	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	8	4
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	8	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	8	3
FYVE/PHD zinc finger	SET domain	8	5
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	8	4
WW domain	WW domain	8	5
Cysteine proteinases	Granulin repeat	8	3
EF-hand	Riboflavin synthase domain-like	8	2
Periplasmic binding protein-like II	ACT-like	8	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	8	5
P-loop containing nucleoside triphosphate hydrolases	TGS-like	8	3
Zn-finger domain of Sec23/24	vWA-like	8	4
Translation proteins	Ribosomal protein S5 domain 2-like	8	4
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	8	4
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	8	2
RING/U-box	TRAF domain-like	8	2
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	8	2
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	8	4
E set domains	Glycosyl hydrolase domain	8	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	8	2
vWA-like	Helical domain of Sec23/24	8	4
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	8	2
PH domain-like	Oxysterol-binding protein-like	8	1
ADC-like	Cdc48 domain 2-like	8	3
UBA-like	UBA-like	8	6
vWA-like	beta-sandwich domain of Sec23/24	8	4
Adenine nucleotide alpha hydrolases-like	RING/U-box	8	2
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	8	4
GST C-terminal domain-like	GST C-terminal domain-like	8	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	8	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	8	6
F-box domain	Tubby C-terminal domain-like	8	3
SNARE fusion complex	SNARE fusion complex	7	2
Toll/Interleukin receptor TIR domain	Mannose-binding lectins	7	4
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	7	1
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	7	5
PUA domain-like	SET domain	7	2
RING/U-box	Cysteine proteinases	7	6
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	7	1
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	7	2
CheY-like	CheY-like	7	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	7	1
RNase III domain-like	dsRNA-binding domain-like	7	6
EF-hand	P-loop containing nucleoside triphosphate hydrolases	7	3
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	7	1
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
POZ domain	TAZ domain	7	2
Homeodomain-like	RING/U-box	7	3
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	7	2
PDZ domain-like	ClpP/crotonase	7	1
Flavoproteins	Riboflavin synthase domain-like	7	3
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	7	2
Translational machinery components	L30e-like	7	3
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	7	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
ISP domain	Bet v1-like	7	3
ARM repeat	TPR-like	7	2
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	7	4
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	7	3
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	7	2
RING/U-box	RNA-binding domain, RBD	7	2
Ribosomal protein L6	Ribosomal protein L6	7	2
Surp module (SWAP domain)	Surp module (SWAP domain)	7	2
Protein kinase-like (PK-like)	KA1-like	7	2
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	7	4
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	7	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	7	2
beta-beta-alpha zinc fingers	Ribonuclease H-like	7	3
E set domains	AMPKBI-like	7	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	7	4
Galactose oxidase, central domain	E set domains	6	2
FF domain	FF domain	6	3
t-snare proteins	SNARE fusion complex	6	3
HIT/MYND zinc finger-like	Cysteine proteinases	6	2
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	6	2
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	2
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	6	2
Rudiment single hybrid motif	Single hybrid motif	6	2
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	2
E set domains	Ankyrin repeat	6	2
YrdC/RibB	RibA-like	6	3
RCC1/BLIP-II	Protein kinase-like (PK-like)	6	3
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	6	2
ARM repeat	Tudor/PWWP/MBT	6	3
Translation proteins	ThrRS/AlaRS common domain	6	3
E set domains	P-loop containing nucleoside triphosphate hydrolases	6	2
Initiation factor IF2/eIF5b, domain 3	Translation proteins	6	2
WW domain	FF domain	6	3
Surp module (SWAP domain)	Ubiquitin-like	6	1
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	6	2
ARM repeat	Clathrin adaptor appendage domain	6	4
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	6	4
Aconitase iron-sulfur domain	LeuD/IlvD-like	6	2
Ankyrin repeat	Protein kinase-like (PK-like)	6	2
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	6	4
CAD & PB1 domains	TPR-like	6	4
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	6	2
DAK1/DegV-like	DhaL-like	6	3
Class II aaRS ABD-related	C-terminal domain of ProRS	6	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	6	2
RNA-binding domain, RBD	PABC (PABP) domain	6	4
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	6	3
PreATP-grasp domain	Single hybrid motif	6	2
Ribonuclease H-like	DNA/RNA polymerases	6	3
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	6	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	6	2
Thioredoxin-like	Cysteine-rich domain	6	5
RCC1/BLIP-II	FYVE/PHD zinc finger	6	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	6	2
Trigger factor ribosome-binding domain	FKBP-like	6	2
POZ domain	Pentapeptide repeat-like	6	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
Homeodomain-like	FAD/NAD(P)-binding domain	6	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	6	3
Chromo domain-like	Homeodomain-like	6	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	6	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	6	1
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	6	2
PH domain-like	RCC1/BLIP-II	6	1
POZ domain	POZ domain	6	4
HD-domain/PDEase-like	Nucleotidyltransferase	6	5
Ubiquitin-like	BAG domain	6	2
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	6	4
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	5	3
PH domain-like	BEACH domain	5	4
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	5	4
Ribonuclease H-like	HRDC-like	5	2
UBA-like	XPC-binding domain	5	3
BEACH domain	WD40 repeat-like	5	4
GAF domain-like	GAF domain-like	5	2
CCCH zinc finger	RING/U-box	5	2
F-box domain	WD40 repeat-like	5	2
Acetyl-CoA synthetase-like	Protein kinase-like (PK-like)	5	1
HAD-like	dsRNA-binding domain-like	5	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	5	3
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	1
USP8 N-terminal domain-like	JAB1/MPN domain	5	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	5	3
Tudor/PWWP/MBT	SET domain	5	3
POZ domain	TPR-like	5	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	5	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	5	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	1
ARM repeat	Sec7 domain	5	4
DNA-binding domain	DNA-binding pseudobarrel domain	5	3
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	5	2
Carbamate kinase-like	ACT-like	5	3
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	5	1
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	5	4
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	5	4
PYP-like sensor domain (PAS domain)	GAF domain-like	5	2
CBS-domain pair	CAD & PB1 domains	5	3
PP2C-like	Protein kinase-like (PK-like)	5	3
Ribosomal L27 protein-like	Nucleic acid-binding proteins	5	2
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	5	2
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	5	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	5	2
Actin-crosslinking proteins	Actin-crosslinking proteins	5	1
Tudor/PWWP/MBT	FYVE/PHD zinc finger	5	3
Ubiquitin-like	XPC-binding domain	5	3
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	5	3
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	5	2
ARID-like	HMG-box	5	2
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	5	3
SPOC domain-like	C-terminal domain of Ku80	5	2
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	5	3
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	5	2
PA domain	Zn-dependent exopeptidases	5	3
Zinc beta-ribbon	Cyclin-like	5	2
PLP-dependent transferases	PLP-dependent transferases	5	4
Ankyrin repeat	RING/U-box	5	2
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	5	3
L domain-like	WD40 repeat-like	5	5
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	5	2
Translation proteins	Translation proteins	5	1
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	5	3
Ubiquitin-like	Zn-binding ribosomal proteins	5	1
SWIB/MDM2 domain	Plus3-like	5	5
Rhomboid-like	UBA-like	5	2
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	5	2
(Phosphotyrosine protein) phosphatases II	E set domains	5	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	5	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	5	2
BAR/IMD domain-like	SH3-domain	5	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	4	1
TPR-like	Thioredoxin-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	4	3
Taf5 N-terminal domain-like	WD40 repeat-like	4	1
Enolase N-terminal domain-like	Enolase C-terminal domain-like	4	2
UBA-like	P-loop containing nucleoside triphosphate hydrolases	4	2
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	4	3
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	4
PH domain-like	Bet v1-like	4	1
FAD/NAD(P)-binding domain	EF-hand	4	3
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	4	2
GST C-terminal domain-like	eEF-1beta-like	4	2
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	4	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	4	2
Thioredoxin-like	Ubiquitin-like	4	3
SET domain	Formin homology 2 domain (FH2 domain)	4	2
Dom34/Pelota N-terminal domain-like	L30e-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	4	2
RNA-binding domain, RBD	DPP6 N-terminal domain-like	4	2
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	4	2
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	4	4
ClpP/crotonase	ClpP/crotonase	4	3
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
PAZ domain	RNase III domain-like	4	4
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	4	4
Chaperone J-domain	4Fe-4S ferredoxins	4	2
Chitinase insertion domain	Protein kinase-like (PK-like)	4	1
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	4	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	4	1
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	4	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Cytidine deaminase-like	Dihydrofolate reductase-like	4	2
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	4	4
Ubiquitin-like	Protein kinase-like (PK-like)	4	2
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	4	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Staphylococcal nuclease	4	2
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	4	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
EF-hand	Calponin-homology domain, CH-domain	4	2
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	4	4
CAD & PB1 domains	RING/U-box	4	2
Arp2/3 complex subunits	Arp2/3 complex subunits	4	2
ARID-like	FYVE/PHD zinc finger	4	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	4	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	4	2
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	4	2
FKBP-like	Triger factor/SurA peptide-binding domain-like	4	1
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	4	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	4	2
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	4	1
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
Actin-crosslinking proteins	(Trans)glycosidases	4	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	4	4
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	4	2
Acetyl-CoA synthetase-like	ACP-like	4	2
PUG domain-like	Ubiquitin-like	4	2
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	4	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	4	2
PH domain-like	WD40 repeat-like	4	3
SMAD/FHA domain	Phospholipase D/nuclease	4	3
PRTase-like	PRTase-like	4	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	4	2
PA domain	Transferrin receptor-like dimerisation domain	4	2
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	4	1
HAD-like	BRCT domain	4	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	4	2
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	4	4
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	4	2
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	4	4
WD40 repeat-like	SNARE fusion complex	4	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	3
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	4	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	4	2
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	4	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	4	3
GAF domain-like	CheY-like	4	3
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	4	1
Ubiquitin-like	Acid proteases	4	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	4	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	4	1
Carbamate kinase-like	ALDH-like	4	1
RING/U-box	UBA-like	4	2
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	4	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	2
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	4	1
vWA-like	SPOC domain-like	4	3
TPR-like	Chaperone J-domain	4	3
(Trans)glycosidases	(Trans)glycosidases	4	3
F-box domain	HCP-like	4	3
Glutamine synthetase/guanido kinase	GatB/YqeY motif	4	2
RING/U-box	PUA domain-like	4	3
PriA/YqbF domain	GINS helical bundle-like	4	2
EF-hand	Mitochondrial carrier	4	2
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	4	2
RING/U-box	Ran binding protein zinc finger-like	4	1
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	4	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	4	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	4	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	4	3
NAD(P)-binding Rossmann-fold domains	Citrate synthase	4	1
SWIB/MDM2 domain	SWIB/MDM2 domain	4	2
Dom34/Pelota N-terminal domain-like	Translational machinery components	4	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	4	3
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	4	1
Clathrin heavy-chain terminal domain	ARM repeat	4	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	4	1
PurM N-terminal domain-like	PurM C-terminal domain-like	3	2
Thioredoxin-like	NHL repeat	3	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	3	2
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	3	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	3	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	3	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	3	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	3	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	3	2
Ubiquitin-like	Cysteine proteinases	3	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	3	3
YjgF-like	YjgF-like	3	3
Tricorn protease domain 2	WD40 repeat-like	3	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
FYVE/PHD zinc finger	Homeodomain-like	3	2
UBC-like	RING/U-box	3	2
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
FYSH domain	beta-beta-alpha zinc fingers	3	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	3	2
Cysteine proteinases	Galactose-binding domain-like	3	3
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	3	1
PUA domain-like	SWIB/MDM2 domain	3	1
ARID-like	HSP20-like chaperones	3	1
TPR-like	PUA domain-like	3	2
ARM repeat	UBA-like	3	2
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	3	2
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	3	2
TATA-box binding protein-like	TATA-box binding protein-like	3	1
Nucleoporin domain	WD40 repeat-like	3	3
Protein kinase-like (PK-like)	UBA-like	3	1
Cystatin/monellin	Cystatin/monellin	3	1
L30e-like	alpha/beta knot	3	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	3	2
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	3	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	3	2
Kelch motif	Metallo-dependent phosphatases	3	1
SWIB/MDM2 domain	GYF domain	3	3
Trypsin-like serine proteases	Trypsin-like serine proteases	3	2
PAZ domain	dsRNA-binding domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	3	3
HAD-like	Riboflavin kinase-like	3	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	3	1
Sec63 N-terminal domain-like	E set domains	3	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	3	1
RNI-like	Glutathione synthetase ATP-binding domain-like	3	1
SWIB/MDM2 domain	eIF1-like	3	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	3	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
FAD/NAD(P)-binding domain	ACP-like	3	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Cysteine proteinases	Formin homology 2 domain (FH2 domain)	3	1
PAH2 domain	PAH2 domain	3	1
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	1
WGR domain-like	ADP-ribosylation	3	3
ACP-like	Heme-dependent catalase-like	3	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
Galactose oxidase, central domain	Galactose oxidase, central domain	3	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	3	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	3	2
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	3	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	3	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	3	1
4Fe-4S ferredoxins	Metallo-hydrolase/oxidoreductase	3	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	3	2
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	3	1
TolB, C-terminal domain	Quinoprotein alcohol dehydrogenase-like	3	1
Double Clp-N motif	Double Clp-N motif	3	1
SAP domain	FYVE/PHD zinc finger	3	2
WD40 repeat-like	DNase I-like	3	1
Ubiquitin-like	HAD-like	3	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	3	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	3	2
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	3	3
Amidase signature (AS) enzymes	TPR-like	3	1
Plus3-like	GYF domain	3	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	3	2
PUA domain-like	Nucleotidylyl transferase	3	1
Ubiquitin-like	Cap-Gly domain	3	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	3	2
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	3	1
GroEL apical domain-like	SAICAR synthase-like	3	2
HisI-like	all-alpha NTP pyrophosphatases	3	2
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	3	2
TolB, C-terminal domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
Granulin repeat	Formin homology 2 domain (FH2 domain)	3	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	3	1
Nucleotidylyl transferase	Nucleotidylyl transferase	3	1
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	3	1
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	3	1
HAD-like	NHL repeat	3	2
Ubiquitin-like	L domain-like	3	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	3	1
RNA-binding domain, RBD	beta-sandwich domain of Sec23/24	3	3
Dcp2 domain-like	Nudix	3	2
SBT domain	Ankyrin repeat	3	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	3	2
PH domain-like	ARM repeat	3	3
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	3	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	3	3
Cytochrome f, large domain	Rudiment single hybrid motif	3	2
Six-hairpin glycosidases	AbfB domain	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	3	2
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	3	1
UBA-like	KA1-like	3	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	3	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	3	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	3	3
PLC-like phosphodiesterases	PLC-like phosphodiesterases	3	2
NTF2-like	Probable bacterial effector-binding domain	3	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	3	1
Restriction endonuclease-like	RuvA domain 2-like	3	2
F-box domain	Actin-like ATPase domain	3	1
PreATP-grasp domain	PreATP-grasp domain	3	2
SMI1/KNR4-like	ApaG-like	3	1
Chaperone J-domain	RNA-binding domain, RBD	3	2
UBA-like	Hect, E3 ligase catalytic domain	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	2
F-box domain	ApaG-like	3	1
Methylglyoxal synthase-like	Cytidine deaminase-like	3	2
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
TPR-like	HSP20-like chaperones	3	2
HAD-like	Thioredoxin-like	3	2
LEA14-like	LEA14-like	3	1
cAMP-binding domain-like	cAMP-binding domain-like	3	2
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	3	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	3	1
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	3	2
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	3	1
F-box domain	SMI1/KNR4-like	3	1
Actin-like ATPase domain	AF1104-like	3	1
DUSP-like	Cysteine proteinases	3	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	3
Saposin	Saposin	3	2
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	3	1
BSD domain-like	BSD domain-like	3	1
TPR-like	SET domain	3	3
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	3	1
PH domain-like	BSD domain-like	3	1
Staphylococcal nuclease	Staphylococcal nuclease	3	2
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	3	2
CAD & PB1 domains	UBA-like	3	1
Ricin B-like lectins	Glycosyl hydrolase domain	3	1
P-loop containing nucleoside triphosphate hydrolases	Outer arm dynein light chain 1	3	2
Aspartate/glutamate racemase	Aspartate/glutamate racemase	3	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	3	2
FYSH domain	Hypothetical protein AF0491, middle domain	3	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	3	2
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	3	1
ACP-like	Trimeric LpxA-like enzymes	3	1
Cytochrome P450	Cytochrome P450	3	3
PUA domain-like	eIF1-like	3	1
HIT-like	HIT-like	3	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	3	1
PH domain-like	Phospholipase D/nuclease	3	2
Nucleotidyltransferase	TGS-like	2	2
Nucleotidyltransferase	EF-hand	2	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	2	1
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
RmlC-like cupins	RmlC-like cupins	2	2
Riboflavin synthase domain-like	Riboflavin synthase domain-like	2	1
YjeF N-terminal domain-like	FMN-binding split barrel	2	2
Protein kinase-like (PK-like)	Activating enzymes of the ubiquitin-like proteins	2	2
TPR-like	Metallo-dependent phosphatases	2	1
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
HD-domain/PDEase-like	TGS-like	2	2
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
ARM repeat	Concanavalin A-like lectins/glucanases	2	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
Carbamate kinase-like	Carbamate kinase-like	2	2
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	2	2
PRP4-like	WD40 repeat-like	2	1
RNA-binding domain, RBD	PWI domain	2	1
Enolase N-terminal domain-like	alpha/beta-Hydrolases	2	1
Second domain of FERM	PH domain-like	2	1
PH domain-like	Ankyrin repeat	2	2
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	2	2
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	2	1
L9 N-domain-like	Ribosomal protein L9 C-domain	2	1
alpha-D-mannose-specific plant lectins	EGF/Laminin	2	2
F-box domain	Clavaminate synthase-like	2	2
Putative DNA-binding domain	Putative DNA-binding domain	2	1
ARM repeat	"Winged helix" DNA-binding domain	2	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	2	2
Ribonuclease H-like	Ribonuclease H-like	2	2
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	2	1
PYP-like sensor domain (PAS domain)	F-box domain	2	1
Cyclophilin-like	Retrovirus zinc finger-like domains	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
Oxidoreductase molybdopterin-binding domain	E set domains	2	2
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	2	2
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
Urease, beta-subunit	Metallo-dependent hydrolases	2	2
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	2	1
Cap-Gly domain	L domain-like	2	1
Thioredoxin-like	FAD-dependent thiol oxidase	2	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	2	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	2
ARM repeat	BEACH domain	2	2
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	2	2
FYVE/PHD zinc finger	SWIB/MDM2 domain	2	2
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	2	2
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	2	2
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	2	1
AN1-like Zinc finger	AN1-like Zinc finger	2	2
Clavaminate synthase-like	RING/U-box	2	1
alpha-D-mannose-specific plant lectins	CBS-domain pair	2	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
Cullin homology domain	Cullin homology domain	2	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	1
UBA-like	Thioredoxin-like	2	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	2	2
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	2	2
Formyltransferase	FMT C-terminal domain-like	2	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	2	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	2	1
ISP transmembrane anchor	ISP domain	2	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	2	2
Surp module (SWAP domain)	ENTH/VHS domain	2	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	2	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	2	1
vWA-like	C-terminal domain of Ku80	2	1
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	2	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
RNA-binding domain, RBD	TPR-like	2	2
HCP-like	HIT/MYND zinc finger-like	2	2
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	2	2
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	2	1
Nucleotide-diphospho-sugar transferases	ARM repeat	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	2
"Winged helix" DNA-binding domain	Zinc beta-ribbon	2	1
PheT/TilS domain	Class II aaRS and biotin synthetases	2	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	2	1
PP2C-like	cAMP-binding domain-like	2	1
RING/U-box	Cyclophilin-like	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
PapD-like	Ankyrin repeat	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	2	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	2	2
RNI-like	Outer arm dynein light chain 1	2	2
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	2	1
DNA clamp	DNA clamp	2	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	1
Protein prenylyltransferase	L domain-like	2	1
PH domain-like	HMG-box	2	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	2	2
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	2	1
Trimeric LpxA-like enzymes	ARM repeat	2	1
Alpha-L RNA-binding motif	Pseudouridine synthase	2	1
DNase I-like	EF-hand	2	2
Second domain of FERM	Prismane protein-like	2	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
BRCT domain	WGR domain-like	2	2
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
Kix domain of CBP (creb binding protein)	RNI-like	2	1
POZ domain	Galactose-binding domain-like	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	1
Concanavalin A-like lectins/glucanases	PH domain-like	2	2
Concanavalin A-like lectins/glucanases	Cysteine proteinases	2	1
ARM repeat	SH3-domain	2	1
BAR/IMD domain-like	PH domain-like	2	2
Class II aaRS and biotin synthetases	Translation proteins	2	2
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	2
FYVE/PHD zinc finger	Plus3-like	2	2
Terpenoid synthases	Terpenoid synthases	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
TPR-like	SMR domain-like	2	2
PUA domain-like	Ribosomal protein S5 domain 2-like	2	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	2	1
E set domains	CBS-domain pair	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Cyclophilin-like	TPR-like	2	1
Nucleotide-binding domain	FAD/NAD(P)-binding domain	2	1
Nucleotidylyl transferase	Tropomyosin	2	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	2	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	2	2
Acid proteases	UBA-like	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	1
BRCT domain	ADP-ribosylation	2	2
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
PDZ domain-like	TPR-like	2	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	2	1
Tropomyosin	Apolipoprotein A-I	2	2
RING/U-box	Formin homology 2 domain (FH2 domain)	2	2
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	2	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	2	1
ITPase-like	ITPase-like	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	2	1
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	1
Histone-fold	ARM repeat	2	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
Ran binding protein zinc finger-like	Translation proteins	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	2
CCCH zinc finger	HIT-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
GroEL-intermediate domain like	GroEL-intermediate domain like	2	1
ArfGap/RecO-like zinc finger	Ankyrin repeat	2	2
RNA-binding domain, RBD	Surp module (SWAP domain)	2	1
RNI-like	SET domain	2	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	2	2
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	2	1
PH domain-like	Prismane protein-like	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Kix domain of CBP (creb binding protein)	F-box domain	2	1
PH domain-like	ArfGap/RecO-like zinc finger	2	2
BAR/IMD domain-like	Ankyrin repeat	2	2
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	2	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	2	2
F-box domain	HIT/MYND zinc finger-like	2	2
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Tropomyosin	Tropomyosin	2	2
Formin homology 2 domain (FH2 domain)	RuBisCo LSMT C-terminal, substrate-binding domain	2	1
RNA-binding domain, RBD	ENTH/VHS domain	2	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	2
Urease, gamma-subunit	Urease, beta-subunit	2	2
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	2	1
HCP-like	Homing endonucleases	2	1
Putative cyclase	Putative cyclase	2	1
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Chaperone J-domain	Thioredoxin-like	2	2
Elongation factor TFIIS domain 2	Zinc beta-ribbon	2	2
PDZ domain-like	PDZ domain-like	2	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	2	1
Nucleoside hydrolase	Nucleoside hydrolase	2	1
E set domains	RNA-binding domain, RBD	2	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
SAP domain	RNA-binding domain, RBD	2	1
Pre-PUA domain	PUA domain-like	2	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	2	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	2	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	2
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	2	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	2	1
Thioredoxin-like	Six-hairpin glycosidases	2	2
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	2	1
TPR-like	HIT/MYND zinc finger-like	2	2
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	2	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	1
HAD-like	NTF2-like	2	2
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	2	1
PX domain	BAR/IMD domain-like	2	2
WD40 repeat-like	Calcium-dependent phosphotriesterase	2	2
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	2
Ribonuclease H-like	RING/U-box	2	2
Dihydrofolate reductase-like	YbiA-like	2	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	2	1
Urease, gamma-subunit	Metallo-dependent hydrolases	2	2
UraD-Like	Transthyretin (synonym: prealbumin)	2	1
BRCT domain	post-AAA+ oligomerization domain-like	2	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	2	1
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	2	2
Heme oxygenase-like	HAD-like	2	2
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	2
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	2	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	2	1
GST C-terminal domain-like	Nucleic acid-binding proteins	2	1
EF-hand	RING/U-box	2	2
F-box domain	SET domain	2	1
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	1
Ankyrin repeat	TPR-like	2	1
Putative DNA-binding domain	PheT/TilS domain	2	1
"Winged helix" DNA-binding domain	E set domains	2	1
Thioredoxin-like	"Winged helix" DNA-binding domain	2	1
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	2	1
TATA-box binding protein-like	DNA-glycosylase	2	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	2	1
FYVE/PHD zinc finger	ARM repeat	2	1
RNI-like	WD40 repeat-like	2	2
FAD/NAD(P)-binding domain	SMAD/FHA domain	2	1
Cytidine deaminase-like	YbiA-like	2	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	2
F-box domain	L domain-like	2	2
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	2	1
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	2	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
PIN domain-like	Chromo domain-like	2	1
HD-domain/PDEase-like	EF-hand	2	1
WD40 repeat-like	Tricorn protease N-terminal domain	2	1
RNA-binding domain, RBD	WW domain	2	2
alpha/beta knot	Nucleic acid-binding proteins	1	1
Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	1	1
N-terminal domain of the delta subunit of the F1F0-ATP synthase	N-terminal domain of the delta subunit of the F1F0-ATP synthase	1	1
BRCT domain	DNA/RNA polymerases	1	1
AF0104/ALDC/Ptd012-like	L domain-like	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
TPR-like	RNI-like	1	1
Cyclophilin-like	RNA-binding domain, RBD	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
F-box domain	YWTD domain	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	NAD(P)-binding Rossmann-fold domains	1	1
SAP domain	WGR domain-like	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
(Phosphotyrosine protein) phosphatases II	Toll/Interleukin receptor TIR domain	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
FAH	FAH	1	1
(Phosphotyrosine protein) phosphatases II	P-loop containing nucleoside triphosphate hydrolases	1	1
Single hybrid motif	ClpP/crotonase	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Skp1 dimerisation domain-like	L domain-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Mitochondrial carrier	1	1
SufE/NifU	BolA-like	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
L domain-like	Cyclin-like	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
C-terminal UvrC-binding domain of UvrB	ApaG-like	1	1
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
SH2 domain	SH2 domain	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
SPOC domain-like	SAP domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PABC (PABP) domain	1	1
RNA-binding domain, RBD	Formin homology 2 domain (FH2 domain)	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Toll/Interleukin receptor TIR domain	1	1
Starch-binding domain-like	Cna protein B-type domain	1	1
alpha-D-mannose-specific plant lectins	DPP6 N-terminal domain-like	1	1
UBC-like	UBA-like	1	1
TAZ domain	TAZ domain	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
Single hybrid motif	Single hybrid motif	1	1
WD40 repeat-like	TPR-like	1	1
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Macro domain-like	HIT-like	1	1
GYF domain	SET domain	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
NAD(P)-binding Rossmann-fold domains	CBS-domain pair	1	1
YgbK-like	Aldolase	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
Ribosomal protein S2	Nucleotide-diphospho-sugar transferases	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
R3H domain	Ankyrin repeat	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Hypothetical protein PA1324	Cna protein B-type domain	1	1
alpha/beta-Hydrolases	Formin homology 2 domain (FH2 domain)	1	1
NAD(P)-binding Rossmann-fold domains	Mitochondrial carrier	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
Ribonuclease H-like	SH2 domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
alpha-D-mannose-specific plant lectins	Quinoprotein alcohol dehydrogenase-like	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
Amidase signature (AS) enzymes	Amidase signature (AS) enzymes	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
beta-sandwich domain of Sec23/24	P-loop containing nucleoside triphosphate hydrolases	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
PUA domain-like	alpha/beta knot	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	1	1
SRF-like	DNase I-like	1	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	1	1
Amine oxidase N-terminal region	ARM repeat	1	1
Pseudouridine synthase	PUA domain-like	1	1
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	Formin homology 2 domain (FH2 domain)	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
Bromodomain	FYVE/PHD zinc finger	1	1
Flavoproteins	Radical SAM enzymes	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
alpha-D-mannose-specific plant lectins	Clc chloride channel	1	1
Aminoacid dehydrogenase-like, N-terminal domain	CBS-domain pair	1	1
CinA-like	Nucleotidylyl transferase	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
TGS-like	ACT-like	1	1
SAP domain	CCCH zinc finger	1	1
HCP-like	Chaperone J-domain	1	1
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
UBA-like	post-AAA+ oligomerization domain-like	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
DNase I-like	DNase I-like	1	1
PH domain-like	GTPase activation domain, GAP	1	1
L domain-like	HMA, heavy metal-associated domain	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
Hypothetical protein PA1324	Carboxypeptidase regulatory domain-like	1	1
SufE/NifU	NadA-like	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
BRCT domain	PsbU/PolX domain-like	1	1
vWA-like	SAP domain	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
WD40 repeat-like	Soluble quinoprotein glucose dehydrogenase	1	1
Thioredoxin-like	VC0467-like	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
Ubiquitin-like	Bromodomain	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Chaperone J-domain	ARM repeat	1	1
SAP domain	SAP domain	1	1
RNI-like	EF-hand	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
Skp1 dimerisation domain-like	Actin-crosslinking proteins	1	1
Amine oxidase catalytic domain	Amine oxidase catalytic domain	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
HMG-box	HMG-box	1	1
L domain-like	ARM repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Hypothetical protein PA1324	Starch-binding domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
Periplasmic binding protein-like II	GlnB-like	1	1
Chaperone J-domain	Homeodomain-like	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
SSo0622-like	Kelch motif	1	1
GYF domain	RNA-binding domain, RBD	1	1
Formin homology 2 domain (FH2 domain)	TPR-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
UBA-like	PUG domain-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
GAT-like domain	GAT-like domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cyclin-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
Ran binding protein zinc finger-like	DNase I-like	1	1
DPP6 N-terminal domain-like	DPP6 N-terminal domain-like	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
SMAD/FHA domain	BRCT domain	1	1
ARID-like	Clavaminate synthase-like	1	1
Protein kinase-like (PK-like)	PH domain-like	1	1
PRC-barrel domain	PRC-barrel domain	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
DNA-glycosylase	Nudix	1	1
POZ domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Lipoxigenase	Lipoxigenase	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Ribosomal protein L22	Ribosomal protein S3 C-terminal domain	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Chaperone J-domain	CSL zinc finger	1	1
PurS-like	PurM N-terminal domain-like	1	1
HD-domain/PDEase-like	ACT-like	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
FYVE/PHD zinc finger	TPR-like	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
POZ domain	Actin-crosslinking proteins	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
beta-sandwich domain of Sec23/24	Galactose-binding domain-like	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
vWA-like	Cysteine-rich domain	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
Nucleic acid-binding proteins	UBA-like	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
Calcium ATPase, transduction domain A	ARM repeat	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Voltage-gated potassium channels	Periplasmic binding protein-like II	1	1
ssDNA-binding transcriptional regulator domain	Retrovirus zinc finger-like domains	1	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
DhaL-like	DhaL-like	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
Pectin lyase-like	Pectin lyase-like	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
Putative isomerase YbhE	RING/U-box	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
DNA-binding domain	FYVE/PHD zinc finger	1	1
GYF domain	CCCH zinc finger	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
Arabinanase/levansucrase/invertase	Arabinanase/levansucrase/invertase	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Ubiquitin-like	Galactose-binding domain-like	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Quinoprotein alcohol dehydrogenase-like	Calcium-dependent phosphotriesterase	1	1
F-box domain	Tricorn protease domain 2	1	1
Calcium ATPase, transmembrane domain M	Calcium ATPase, transmembrane domain M	1	1
TGS-like	Class II aaRS ABD-related	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
DNA-binding domain	Bromodomain	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
Clavaminate synthase-like	Clavaminate synthase-like	1	1
F-box domain	Pectin lyase-like	1	1
Carboxypeptidase regulatory domain-like	Cna protein B-type domain	1	1
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
beta-sandwich domain of Sec23/24	Band 7/SPFH domain	1	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
Pseudo ankyrin repeat-like	Ankyrin repeat	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
PHL pollen allergen	PHL pollen allergen	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
L domain-like	Calcium-dependent phosphotriesterase	1	1
SAP domain	DNase I-like	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
DPP6 N-terminal domain-like	Protein kinase-like (PK-like)	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
MFS general substrate transporter	PUA domain-like	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
Chromo domain-like	Ankyrin repeat	1	1
E set domains	E set domains	1	1
Ubiquitin-like	Homeodomain-like	1	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
beta-sandwich domain of Sec23/24	NAD(P)-binding Rossmann-fold domains	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	P-loop containing nucleoside triphosphate hydrolases	1	1
Protease propeptides/inhibitors	PA domain	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	S13-like H2TH domain	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
RNI-like	ARM repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein cytoplasmic domain-like	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
P-loop containing nucleoside triphosphate hydrolases	Cation efflux protein transmembrane domain-like	1	1
POZ domain	WD40 repeat-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Lysozyme-like	Lysozyme-like	1	1
Protein kinase-like (PK-like)	PLP-dependent transferases	1	1
Tudor/PWWP/MBT	RNA-binding domain, RBD	1	1
BRCT domain	FYVE/PHD zinc finger	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Chaperone J-domain	E set domains	1	1
Cysteine proteinases	UBA-like	1	1
EF-hand	TPR-like	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
Starch-binding domain-like	Phosphoglycerate mutase-like	1	1
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Tex N-terminal region-like	SH2 domain	1	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
RuvA domain 2-like	SH2 domain	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
SMAD/FHA domain	PP2C-like	1	1
TAZ domain	RING/U-box	1	1
SAP domain	ADP-ribosylation	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
L domain-like	FabD/lysophospholipase-like	1	1
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	1	1
SWIB/MDM2 domain	CCCH zinc finger	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
TAZ domain	FYVE/PHD zinc finger	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
Ammonium transporter	Ammonium transporter	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Aminopeptidase/glucanase lid domain	Aminopeptidase/glucanase lid domain	1	1
WD40 repeat-like	Bromodomain	1	1
CarD-like	TRCF domain-like	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Quinoprotein alcohol dehydrogenase-like	SNARE fusion complex	1	1
PUA domain-like	PUA domain-like	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Photosystem I reaction center subunit XI, PsaL	Photosystem I reaction center subunit XI, PsaL	1	1
FYVE/PHD zinc finger	GYF domain	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
Plus3-like	CCCH zinc finger	1	1
Helical scaffold and wing domains of SecA	Helical scaffold and wing domains of SecA	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Six-hairpin glycosidases	Carbohydrate-binding domain	1	1
S13-like H2TH domain	Ribosomal protein S5 domain 2-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	"Winged helix" DNA-binding domain	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
BRCT domain	Nucleotidyltransferase	1	1
L domain-like	EF-hand	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
Acyl-CoA binding protein	Kelch motif	1	1
Formin homology 2 domain (FH2 domain)	P-loop containing nucleoside triphosphate hydrolases	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
DAK1/DegV-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ubiquitin-like	TPR-like	1	1
ACT-like	Formyltransferase	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
Translation proteins	PRC-barrel domain	1	1
AN1-like Zinc finger	beta-beta-alpha zinc fingers	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
WW domain	P-loop containing nucleoside triphosphate hydrolases	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
DAK1/DegV-like	Ribosomal protein S5 domain 2-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
Nucleotidyltransferase	ACT-like	1	1
Nucleoporin domain	Quinoprotein alcohol dehydrogenase-like	1	1
Amine oxidase catalytic domain	ARM repeat	1	1
PDZ domain-like	Rubredoxin-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Kix domain of CBP (creb binding protein)	Kix domain of CBP (creb binding protein)	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Cytochrome b559 subunits	Cytochrome b559 subunits	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
Ankyrin repeat	Subtilisin-like	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
Smc hinge domain	Tropomyosin	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
E set domains	Riboflavin synthase domain-like	1	1
F-box domain	NTF2-like	1	1
ARM repeat	POZ domain	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
F-box domain	Putative isomerase YbhE	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
NAD(P)-linked oxidoreductase	NAD(P)-linked oxidoreductase	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Toll/Interleukin receptor TIR domain	Homeodomain-like	1	1
Macro domain-like	Macro domain-like	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
Nucleic acid-binding proteins	TPR-like	1	1
PurS-like	PurM C-terminal domain-like	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1