Domain combination pairs in Hymenolepis microstoma

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1500 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	75	24
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	69	38
RNA-binding domain, RBD	RNA-binding domain, RBD	45	24
Immunoglobulin	Immunoglobulin	40	34
Cadherin-like	Cadherin-like	38	23
Actin-like ATPase domain	Actin-like ATPase domain	30	12
POZ domain	Kelch motif	24	9
EGF/Laminin	EGF/Laminin	24	21
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	24	4
ARM repeat	ARM repeat	23	14
DNA/RNA polymerases	Ribonuclease H-like	22	11
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	21	9
Second domain of FERM	PH domain-like	20	15
Fibronectin type III	Fibronectin type III	20	17
WD40 repeat-like	WD40 repeat-like	18	12
TPR-like	TPR-like	18	11
SH3-domain	SH2 domain	17	10
PDZ domain-like	PDZ domain-like	17	15
Immunoglobulin	Fibronectin type III	16	15
SH2 domain	Protein kinase-like (PK-like)	16	9
SH3-domain	Protein kinase-like (PK-like)	16	8
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	16	12
EF-hand	EF-hand	15	9
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	15	9
HAD-like	Calcium ATPase, transmembrane domain M	15	6
Ubiquitin-like	Second domain of FERM	15	11
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	15	6
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	14	5
FYVE/PHD zinc finger	FYVE/PHD zinc finger	14	14
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	14	5
Calcium ATPase, transduction domain A	HAD-like	14	5
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	14	5
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	14	8
Ubiquitin-like	PH domain-like	14	9
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	13	10
Protein kinase-like (PK-like)	ARM repeat	13	11
Ubiquitin-like	Ubiquitin-like	13	7
Growth factor receptor domain	Growth factor receptor domain	13	13
Cyclin-like	Cyclin-like	13	8
Ankyrin repeat	Ankyrin repeat	12	10
PH domain-like	PH domain-like	12	11
Spectrin repeat	Spectrin repeat	12	11
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	12	6
RING/U-box	RING/U-box	11	9
PH domain-like	DBL homology domain (DH-domain)	11	11
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	11	8
Voltage-gated potassium channels	Voltage-gated potassium channels	11	8
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	10	8
GroEL equatorial domain-like	GroEL-intermediate domain like	10	1
POZ domain	Voltage-gated potassium channels	10	3
Thioredoxin-like	GST C-terminal domain-like	10	3
GroEL-intermediate domain like	GroEL apical domain-like	10	1
Cullin repeat-like	Cullin homology domain	10	4
GroEL equatorial domain-like	GroEL apical domain-like	10	1
SH3-domain	SH3-domain	10	10
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	9	2
EF-hand	DLC	9	2
Cullin homology domain	"Winged helix" DNA-binding domain	9	4
L domain-like	L domain-like	9	9
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	9	6
MFS general substrate transporter	MFS general substrate transporter	8	5
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	8	6
SH2 domain	PH domain-like	8	8
Acid proteases	DNA/RNA polymerases	8	3
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	8	7
BPTI-like	BPTI-like	8	7
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	8	8
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	8	2
Homeodomain-like	Homeodomain-like	8	8
Calponin-homology domain, CH-domain	Spectrin repeat	8	7
EGF/Laminin	Growth factor receptor domain	8	8
Cullin repeat-like	"Winged helix" DNA-binding domain	8	3
Voltage-gated potassium channels	cAMP-binding domain-like	8	5
FYVE/PHD zinc finger	Bromodomain	7	7
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	7	7
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	7	7
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	7	4
Nucleic acid-binding proteins	Nucleic acid-binding proteins	7	5
L domain-like	Immunoglobulin	7	2
lambda repressor-like DNA-binding domains	Homeodomain-like	7	4
Chromo domain-like	Chromo domain-like	7	5
Protein kinase-like (PK-like)	Cysteine-rich domain	7	7
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	7	4
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	7	2
cAMP-binding domain-like	cAMP-binding domain-like	7	6
Periplasmic binding protein-like I	Periplasmic binding protein-like II	7	6
Periplasmic binding protein-like II	Voltage-gated potassium channels	6	5
Thioredoxin-like	Thioredoxin-like	6	5
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	6	3
BAR/IMD domain-like	SH3-domain	6	4
C-type lectin-like	C-type lectin-like	6	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	6	6
EGF/Laminin	TSP-1 type 1 repeat	6	4
PDZ domain-like	SH3-domain	6	6
F-box domain	WD40 repeat-like	6	5
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	6	6
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	6	6
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	6	4
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	6	5
TSP-1 type 1 repeat	TSP-1 type 1 repeat	6	6
LDL receptor-like module	LDL receptor-like module	6	6
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	6	3
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	6	3
ABC transporter transmembrane region	ABC transporter transmembrane region	6	5
Immunoglobulin	Protein kinase-like (PK-like)	6	5
FYVE/PHD zinc finger	RING/U-box	6	6
BRCT domain	BRCT domain	6	6
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	6	5
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	5	2
Spectrin repeat	EF-hand	5	4
SH2 domain	SH2 domain	5	4
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	5	3
Phospholipase D/nuclease	Phospholipase D/nuclease	5	4
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	5	4
Cysteine-rich domain	Cysteine-rich domain	5	5
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	5	3
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	5	5
Bromodomain	Bromodomain	5	4
L domain-like	Protein kinase-like (PK-like)	5	5
Fibronectin type III	Protein kinase-like (PK-like)	5	5
TPR-like	SET domain	5	3
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	5	2
SAM/Pointed domain	SAM/Pointed domain	5	5
ARM repeat	WD40 repeat-like	5	5
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	5	3
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	5	2
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	5	3
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	5	5
L domain-like	Growth factor receptor domain	5	5
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	5	4
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	5	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	3
PK beta-barrel domain-like	PK C-terminal domain-like	5	2
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	5	2
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	5	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	5	4
Protein kinase-like (PK-like)	PH domain-like	5	5
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	5	4
Spectrin repeat	PH domain-like	5	5
Translation proteins	EF-G C-terminal domain-like	5	4
PH domain-like	SH3-domain	5	5
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	5	4
Growth factor receptor domain	Protein kinase-like (PK-like)	5	5
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	3
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	5	4
E set domains	E set domains	5	5
Ankyrin repeat	Protein kinase-like (PK-like)	5	5
Periplasmic binding protein-like I	Voltage-gated potassium channels	5	4
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	4	3
HMG-box	HMG-box	4	2
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	4	2
WW domain	WW domain	4	4
Subtilisin-like	Galactose-binding domain-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	4	3
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	4	4
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	4	3
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	4	3
DBL homology domain (DH-domain)	SH3-domain	4	4
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	4	4
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	4	4
beta-sandwich domain of Sec23/24	vWA-like	4	3
Calponin-homology domain, CH-domain	EF-hand	4	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	4
PH domain-like	BEACH domain	4	4
Kelch motif	Kelch motif	4	3
Integrin alpha N-terminal domain	Integrin domains	4	3
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	4
Myosin rod fragments	Myosin rod fragments	4	4
POZ domain	Skp1 dimerisation domain-like	4	2
RING/U-box	B-box zinc-binding domain	4	4
F-box domain	RNI-like	4	3
Protein kinase-like (PK-like)	KA1-like	4	3
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	4	4
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	4	4
UBC-like	RING/U-box	4	4
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	4	4
(Trans)glycosidases	Glycosyl hydrolase domain	4	4
Cysteine proteinases	EF-hand	4	3
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	4	2
Protein kinase-like (PK-like)	Nucleotide cyclase	4	4
Calponin-homology domain, CH-domain	PH domain-like	4	4
HSP20-like chaperones	HSP20-like chaperones	4	1
GroES-like	NAD(P)-binding Rossmann-fold domains	4	3
Concanavalin A-like lectins/glucanases	EGF/Laminin	4	4
SMAD MH1 domain	SMAD/FHA domain	4	3
Translation proteins	Ribosomal protein S5 domain 2-like	4	3
TAZ domain	Kix domain of CBP (creb binding protein)	4	3
Sec7 domain	PH domain-like	4	2
Ubiquitin-like	Protein kinase-like (PK-like)	4	4
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	4	4
Zn-finger domain of Sec23/24	vWA-like	4	3
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	4	2
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	4	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	4	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	4	2
CBS-domain pair	CBS-domain pair	4	3
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	4	4
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	4	2
WD40 repeat-like	RING/U-box	4	4
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	4	4
BEACH domain	WD40 repeat-like	4	4
ENTH/VHS domain	GAT-like domain	4	4
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	4	4
Cysteine-rich domain	C2 domain (Calcium/lipid-binding domain, CaLB)	4	3
PH domain-like	Concanavalin A-like lectins/glucanases	4	4
CoA-dependent acyltransferases	CoA-dependent acyltransferases	3	2
FKBP-like	TPR-like	3	2
Galactose-binding domain-like	Growth factor receptor domain	3	2
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	3
RNA-binding domain, RBD	PABC (PABP) domain	3	3
PH domain-like	PDZ domain-like	3	3
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	3	2
ARM repeat	Toll/Interleukin receptor TIR domain	3	3
ARID-like	FYVE/PHD zinc finger	3	2
cAMP-binding domain-like	Protein kinase-like (PK-like)	3	2
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	3	3
PH domain-like	Oxysterol-binding protein-like	3	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	3	2
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	3	3
Cysteine-rich domain	GTPase activation domain, GAP	3	3
FYVE/PHD zinc finger	Clavaminate synthase-like	3	2
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	1
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	3	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	3	1
RING/U-box	P-loop containing nucleoside triphosphate hydrolases	3	3
TAZ domain	Bromodomain	3	3
Ankyrin repeat	DEATH domain	3	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
GTPase activation domain, GAP	SH2 domain	3	3
FAS1 domain	FAS1 domain	3	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	3	2
FYVE/PHD zinc finger	Tudor/PWWP/MBT	3	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	3	3
Nucleic acid-binding proteins	Translation proteins SH3-like domain	3	3
Bromodomain	RING/U-box	3	3
TAZ domain	TAZ domain	3	3
Calponin-homology domain, CH-domain	GAS2 domain-like	3	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	3	2
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	3	3
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	3	2
Ankyrin repeat	PDZ domain-like	3	1
L27 domain	PDZ domain-like	3	3
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	3	2
SNARE fusion complex	SNARE fusion complex	3	3
P-loop containing nucleoside triphosphate hydrolases	EF-hand	3	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
Sec63 N-terminal domain-like	E set domains	3	3
ARM repeat	Clathrin adaptor appendage domain	3	3
Tropomyosin	Tropomyosin	3	2
TAZ domain	RING/U-box	3	3
PH domain-like	WD40 repeat-like	3	3
Myosin rod fragments	Tropomyosin	3	3
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	3	3
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	E set domains	3	3
PriA/YqbF domain	GINS helical bundle-like	3	2
dsRNA-binding domain-like	dsRNA-binding domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
PH domain-like	ARM repeat	3	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	3	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	3	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
SAM/Pointed domain	Toll/Interleukin receptor TIR domain	3	3
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	3
ARID-like	Clavaminate synthase-like	3	2
Intermediate filament protein, coiled coil region	Intermediate filament protein, coiled coil region	3	2
FYVE/PHD zinc finger	SET domain	3	3
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	3	2
Thioredoxin-like	Ubiquitin-like	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	3	2
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	3	1
Calpain large subunit, middle domain (domain III)	EF-hand	3	2
RING/U-box	Cysteine proteinases	3	3
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	3	3
Ribonuclease H-like	Ribonuclease H-like	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	3	3
PAZ domain	Ribonuclease H-like	3	2
ARM repeat	SAM/Pointed domain	3	3
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	3	3
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	3	3
Cysteine proteinases	Cysteine proteinases	3	3
EF-hand	RING/U-box	3	3
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
RNase III domain-like	RNase III domain-like	3	2
PH domain-like	ArfGap/RecO-like zinc finger	3	3
vWA-like	Helical domain of Sec23/24	3	2
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	2
RING/U-box	TRAF domain-like	3	3
Growth factor receptor domain	Fibronectin type III	3	3
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	3	3
CCCH zinc finger	CCCH zinc finger	3	3
Actin depolymerizing proteins	Actin depolymerizing proteins	3	3
FYVE/PHD zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	3	2
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	2
Spermadhesin, CUB domain	Spermadhesin, CUB domain	3	3
TPR-like	HCP-like	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	3	3
Immunoglobulin	LDL receptor-like module	3	3
Thiolase-like	Thiolase-like	3	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	3	2
Clc chloride channel	CBS-domain pair	3	2
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	3	2
DLC	DLC	3	2
TATA-box binding protein-like	TATA-box binding protein-like	3	3
Ubiquitin-like	Cysteine proteinases	2	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	2	2
Cysteine proteinases	UBA-like	2	2
BAR/IMD domain-like	PH domain-like	2	2
Regulator of G-protein signaling, RGS	Ubiquitin-like	2	2
Mitochondrial carrier	Mitochondrial carrier	2	1
Single hybrid motif	CoA-dependent acyltransferases	2	2
TPR-like	Fic-like	2	1
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	2	2
vWA-like	SPOC domain-like	2	2
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	2	2
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
I/LWEQ domain	I/LWEQ domain	2	2
B-box zinc-binding domain	FYVE/PHD zinc finger	2	2
HAD-like	Calpain large subunit, middle domain (domain III)	2	2
FYVE/PHD zinc finger	Homeodomain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	2	1
Nucleic acid-binding proteins	BRCT domain	2	2
Ubiquitin-like	BAG domain	2	1
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	2	2
WW domain	FF domain	2	2
Translation proteins	Initiation factor IF2/eIF5b, domain 3	2	2
P-loop containing nucleoside triphosphate hydrolases	Concanavalin A-like lectins/glucanases	2	2
Ribonuclease H-like	RuvA domain 2-like	2	2
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	2	2
EGF/Laminin	Notch domain	2	2
Cap-Gly domain	Cap-Gly domain	2	2
Galactose mutarotase-like	(Trans)glycosidases	2	2
Calponin-homology domain, CH-domain	E set domains	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	2	2
Concanavalin A-like lectins/glucanases	WD40 repeat-like	2	2
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	2	2
Mib/herc2 domain-like	Mib/herc2 domain-like	2	2
PH domain-like	EF-hand	2	2
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	2	1
WD40 repeat-like	POZ domain	2	2
Arginase/deacetylase	Arginase/deacetylase	2	2
WW domain	GTPase activation domain, GAP	2	2
Protein kinase-like (PK-like)	PDZ domain-like	2	2
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	2	1
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	2	2
PH domain-like	Ankyrin repeat	2	2
SH2 domain	(Phosphotyrosine protein) phosphatases II	2	1
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	2	2
Succinyl-CoA synthetase domains	NAD(P)-binding Rossmann-fold domains	2	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	2	1
PH domain-like	I/LWEQ domain	2	2
Cyclophilin-like	RNA-binding domain, RBD	2	2
Integrin domains	Integrin domains	2	2
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
RING/U-box	TPR-like	2	2
HAD-like	Cysteine proteinases	2	2
RING/U-box	Ankyrin repeat	2	2
Kix domain of CBP (creb binding protein)	RING/U-box	2	2
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
Arp2/3 complex subunits	Arp2/3 complex subunits	2	2
C-type lectin-like	Complement control module/SCR domain	2	1
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	2	1
BRK domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	2	2
Sec7 domain	ARM repeat	2	2
Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	2	1
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	2	2
Nucleotidylyl transferase	Nucleotidylyl transferase	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	2	2
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	1
PDZ domain-like	"Winged helix" DNA-binding domain	2	2
Tudor/PWWP/MBT	Tudor/PWWP/MBT	2	2
SH3-domain	EF-hand	2	2
Chaperone J-domain	Thioredoxin-like	2	1
BAR/IMD domain-like	GTPase activation domain, GAP	2	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	2	2
POZ domain	Galactose oxidase, central domain	2	2
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	2	2
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	2	1
Metallo-dependent phosphatases	FYVE/PHD zinc finger	2	2
P-loop containing nucleoside triphosphate hydrolases	HAD-like	2	2
WGR domain-like	ADP-ribosylation	2	2
Ubiquitin-like	ARM repeat	2	2
Bet v1-like	Calpain large subunit, middle domain (domain III)	2	2
Immunoglobulin	EGF/Laminin	2	2
A middle domain of Talin 1	I/LWEQ domain	2	2
RING/U-box	RNA-binding domain, RBD	2	2
RNA-binding domain, RBD	SPOC domain-like	2	2
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	2	1
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	2	2
Ubiquitin-like	PDZ domain-like	2	2
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
EF-hand	WD40 repeat-like	2	2
FYVE/PHD zinc finger	SMAD/FHA domain	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	2	2
CCCH zinc finger	RNA-binding domain, RBD	2	2
Galactose mutarotase-like	Glycosyl hydrolase domain	2	2
PP2C-like	PP2C-like	2	2
Bet v1-like	HAD-like	2	2
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	2	2
Bromodomain	Tudor/PWWP/MBT	2	2
Tudor/PWWP/MBT	HIV integrase-binding domain	2	1
PDZ domain-like	Glucocorticoid receptor-like (DNA-binding domain)	2	1
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	2	2
ARM repeat	Subdomain of clathrin and coatomer appendage domain	2	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Second domain of FERM	Concanavalin A-like lectins/glucanases	2	2
PH domain-like	FYVE/PHD zinc finger	2	2
Thioredoxin-like	Galactose-binding domain-like	2	2
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	2	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	2	2
Ubiquitin-like	DBL homology domain (DH-domain)	2	2
HCP-like	HCP-like	2	2
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
Translation proteins	ThrRS/AlaRS common domain	2	1
Glutaminase/Asparaginase	Ankyrin repeat	2	1
E set domains	AMPKBI-like	2	1
ADC-like	Cdc48 domain 2-like	2	1
Translational machinery components	L30e-like	2	2
RBP11-like subunits of RNA polymerase	RBP11-like subunits of RNA polymerase	2	1
ARM repeat	BEACH domain	2	2
(Trans)glycosidases	Galactose-binding domain-like	2	2
SH3-domain	Isochorismatase-like hydrolases	2	2
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	2	2
EGF/Laminin	Ankyrin repeat	2	2
beta-beta-alpha zinc fingers	Homeodomain-like	2	2
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	2	2
Chaperone J-domain	Homeodomain-like	2	2
Immunoglobulin	TSP-1 type 1 repeat	2	2
Second domain of FERM	I/LWEQ domain	2	2
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	2	2
Mib/herc2 domain-like	RING/U-box	2	2
Second domain of FERM	A middle domain of Talin 1	2	2
Putative DNA-binding domain	SAND domain-like	2	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	2	1
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	2	2
PH domain-like	GTPase activation domain, GAP	2	2
RUN domain-like	Ypt/Rab-GAP domain of gyp1p	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
UBA-like	Ubiquitin-like	2	2
Nucleotide-binding domain	FMN-linked oxidoreductases	2	2
Ankyrin repeat	Hect, E3 ligase catalytic domain	2	2
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
Ras GEF	Ras GEF	2	2
Immunoglobulin	Growth factor receptor domain	2	2
Ubiquitin-like	Cysteine-rich domain	2	2
Second domain of FERM	Moesin tail domain	2	2
RNI-like	ARM repeat	2	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	2	2
SRCR-like	SRCR-like	2	2
Pre-PUA domain	PUA domain-like	2	1
Retrovirus zinc finger-like domains	P-loop containing nucleoside triphosphate hydrolases	2	1
Nucleotide cyclase	Nucleotide cyclase	2	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	2	2
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	2	1
DUSP-like	Cysteine proteinases	2	2
ARM repeat	"Winged helix" DNA-binding domain	2	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	2	2
SH2 domain	SOCS box-like	2	1
Tex N-terminal region-like	RuvA domain 2-like	2	2
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
ARM repeat	Formin homology 2 domain (FH2 domain)	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	EGF/Laminin	2	1
CRAL/TRIO domain	GTPase activation domain, GAP	2	1
Ubiquitin-like	Concanavalin A-like lectins/glucanases	2	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	2	1
WD40 repeat-like	FYVE/PHD zinc finger	2	2
SNARE-like	SNARE fusion complex	2	1
Bromodomain	HIT/MYND zinc finger-like	2	2
Tex N-terminal region-like	Ribonuclease H-like	2	2
Kix domain of CBP (creb binding protein)	Bromodomain	2	2
ARM repeat	Ankyrin repeat	2	2
"Winged helix" DNA-binding domain	E set domains	2	2
Galactose-binding domain-like	Galactose-binding domain-like	2	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	2
Ras GEF	PH domain-like	2	2
FF domain	FF domain	2	2
Bet v1-like	Cysteine proteinases	2	2
Class II aaRS and biotin synthetases	Translation proteins	2	1
DNA/RNA polymerases	DNA/RNA polymerases	2	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	2	1
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	2	2
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	2	2
Zinc beta-ribbon	Cyclin-like	2	2
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
Protein kinase-like (PK-like)	Polo-box domain	2	2
L domain-like	Fibronectin type III	2	2
SMAD/FHA domain	"Winged helix" DNA-binding domain	2	2
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	2	2
FYVE/PHD zinc finger	HIT/MYND zinc finger-like	2	2
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	2	2
Periplasmic binding protein-like II	Periplasmic binding protein-like II	2	2
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	2	2
PH domain-like	A middle domain of Talin 1	2	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	2	2
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	2	2
p53-like transcription factors	E set domains	2	2
Cysteine-rich DNA binding domain, (DM domain)	Cysteine-rich DNA binding domain, (DM domain)	2	2
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	2	2
Acid proteases	Acid proteases	2	1
Sema domain	Plexin repeat	2	2
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	2	1
RuvA domain 2-like	RuvA domain 2-like	2	2
Tudor/PWWP/MBT	SAM/Pointed domain	2	2
Homeodomain-like	(Phosphotyrosine protein) phosphatases II	2	2
alpha-helical ferredoxin	FMN-linked oxidoreductases	2	2
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	2	2
TPR-like	P-loop containing nucleoside triphosphate hydrolases	2	2
"Winged helix" DNA-binding domain	PH domain-like	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	2
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	2	2
PH domain-like	Moesin tail domain	2	2
SAP domain	RNA-binding domain, RBD	2	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	2	2
Nucleotidylyl transferase	P-loop containing nucleoside triphosphate hydrolases	2	2
Protein prenylyltransferase	Outer arm dynein light chain 1	2	1
Second domain of FERM	DBL homology domain (DH-domain)	2	2
Notch domain	Ankyrin repeat	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	1
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	2	1
WW domain	Hect, E3 ligase catalytic domain	2	2
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	2	1
AN1-like Zinc finger	AN1-like Zinc finger	2	1
RNI-like	L domain-like	2	2
Ankyrin repeat	HIT/MYND zinc finger-like	2	2
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	2	2
RCC1/BLIP-II	Chaperone J-domain	2	1
Subtilisin-like	Growth factor receptor domain	2	1
EF-hand	Mitochondrial carrier	2	2
Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	2	2
Cysteine-rich domain	SH2 domain	2	2
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	2	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	2
HAD-like	Ankyrin repeat	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
Protein kinase-like (PK-like)	NAD(P)-binding Rossmann-fold domains	1	1
Arginase/deacetylase	RING/U-box	1	1
P-loop containing nucleoside triphosphate hydrolases	LigT-like	1	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
WGR domain-like	Periplasmic binding protein-like I	1	1
TGS-like	Class II aaRS ABD-related	1	1
Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	1	1
PreATP-grasp domain	Rudiment single hybrid motif	1	1
Protein kinase-like (PK-like)	Kelch motif	1	1
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	1	1
Chromo domain-like	BRK domain-like	1	1
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	dsRNA-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
CAD & PB1 domains	Protein kinase-like (PK-like)	1	1
Pseudouridine synthase	PUA domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Multidrug efflux transporter AcrB transmembrane domain	1	1
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	1	1
Translational machinery components	Head domain of nucleotide exchange factor GrpE	1	1
CCHHC domain	CCHHC domain	1	1
FYVE/PHD zinc finger	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
L domain-like	EGF/Laminin	1	1
SAP domain	Concanavalin A-like lectins/glucanases	1	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	1	1
ADP-ribosylation	ADP-ribosylation	1	1
GAF domain-like	GAF domain-like	1	1
Concanavalin A-like lectins/glucanases	ARM repeat	1	1
SAM/Pointed domain	"Winged helix" DNA-binding domain	1	1
"Winged helix" DNA-binding domain	SAICAR synthase-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	CCCH zinc finger	1	1
Immunoglobulin	DPP6 N-terminal domain-like	1	1
YWTD domain	LDL receptor-like module	1	1
Ankyrin repeat	FabD/lysophospholipase-like	1	1
Immunoglobulin	Heme-dependent peroxidases	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
Growth factor receptor domain	(Phosphotyrosine protein) phosphatases II	1	1
B-box zinc-binding domain	Concanavalin A-like lectins/glucanases	1	1
Chromo domain-like	ARM repeat	1	1
EGF/Laminin	YWTD domain	1	1
CAD & PB1 domains	Cysteine-rich domain	1	1
EF-hand	TSP-1 type 1 repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	1	1
Protein kinase-like (PK-like)	Histone-fold	1	1
ADP-ribosylation	Voltage-gated potassium channels	1	1
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
Concanavalin A-like lectins/glucanases	Putative isomerase YbhE	1	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	1	1
Ubiquitin-like	"Winged helix" DNA-binding domain	1	1
CCCH zinc finger	CSL zinc finger	1	1
GFP-like	Growth factor receptor domain	1	1
SH2 domain	Isochorismatase-like hydrolases	1	1
"Winged helix" DNA-binding domain	Moesin tail domain	1	1
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	1	1
RNA-binding domain, RBD	Regulator of G-protein signaling, RGS	1	1
WGR domain-like	Periplasmic binding protein-like II	1	1
PDZ domain-like	Regulator of G-protein signaling, RGS	1	1
Cysteine proteinases	alpha/beta-Hydrolases	1	1
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	1	1
TSP type-3 repeat	TSP type-3 repeat	1	1
Cadherin-like	Concanavalin A-like lectins/glucanases	1	1
SAM/Pointed domain	SH2 domain	1	1
RING/U-box	Chaperone J-domain	1	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	1	1
E set domains	GTPase activation domain, GAP	1	1
RING/U-box	Concanavalin A-like lectins/glucanases	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
RNase III domain-like	dsRNA-binding domain-like	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
SAM/Pointed domain	GTPase activation domain, GAP	1	1
RNI-like	WD40 repeat-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex, superhelical domain	1	1
L9 N-domain-like	Phosphoglucomutase, first 3 domains	1	1
RING/U-box	Regulator of G-protein signaling, RGS	1	1
Ribonuclease H-like	"Winged helix" DNA-binding domain	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Protein kinase-like (PK-like)	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Nucleotide cyclase	A DNA-binding domain in eukaryotic transcription factors	1	1
Ribosomal protein S5 domain 2-like	alpha/beta-Hydrolases	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Protein kinase-like (PK-like)	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
ARM repeat	SH2 domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
EF-hand	DBL homology domain (DH-domain)	1	1
HAD-like	Acyl-CoA binding protein	1	1
Protease propeptides/inhibitors	Galactose-binding domain-like	1	1
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	1	1
beta-beta-alpha zinc fingers	EGF/Laminin	1	1
beta-beta-alpha zinc fingers	FYVE/PHD zinc finger	1	1
cAMP-binding domain-like	Ras GEF	1	1
GTPase activation domain, GAP	Bet v1-like	1	1
Protein kinase-like (PK-like)	Cysteine proteinases	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
Kelch motif	Alpha-L RNA-binding motif	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	1	1
RING/U-box	Phospholipase D/nuclease	1	1
HAD-like	BRCT domain	1	1
PH domain-like	Trm112p-like	1	1
Annexin	Annexin	1	1
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
EF-hand	POZ domain	1	1
Supernatant protein factor (SPF), C-terminal domain	NAD(P)-binding Rossmann-fold domains	1	1
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	1	1
SAM/Pointed domain	RING/U-box	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
Ribonuclease PH domain 2-like	Nop domain	1	1
ARM repeat	FYVE/PHD zinc finger	1	1
Domain of poly(ADP-ribose) polymerase	ENTH/VHS domain	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
EF-hand	Nop domain	1	1
Metallo-dependent phosphatases	Thiamin diphosphate-binding fold (THDP-binding)	1	1
Protein kinase-like (PK-like)	Chaperone J-domain	1	1
t-snare proteins	Nucleotidylyl transferase	1	1
WD40 repeat-like	Nucleoporin domain	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	1	1
L domain-like	PDZ domain-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
SAM/Pointed domain	PDZ domain-like	1	1
Plexin repeat	TSP-1 type 1 repeat	1	1
Domain of poly(ADP-ribose) polymerase	Periplasmic binding protein-like I	1	1
FYVE/PHD zinc finger	Concanavalin A-like lectins/glucanases	1	1
The spindle assembly checkpoint protein mad2	FYVE/PHD zinc finger	1	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	1	1
Spermadhesin, CUB domain	EGF/Laminin	1	1
TNF receptor-like	TNF receptor-like	1	1
Acyl-CoA N-acyltransferases (Nat)	ARM repeat	1	1
BAR/IMD domain-like	SH2 domain	1	1
Indigoidine synthase A-like	Ribokinase-like	1	1
WGR domain-like	ENTH/VHS domain	1	1
Band 7/SPFH domain	SCP-like	1	1
RING/U-box	WWE domain	1	1
Tetraspanin	EF-hand	1	1
beta-beta-alpha zinc fingers	cAMP-binding domain-like	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
Plakin repeat	Plakin repeat	1	1
CCCH zinc finger	CHY zinc finger-like	1	1
PX domain	Phospholipase D/nuclease	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	1	1
RNA-binding domain, RBD	PF0523-like	1	1
TSP-1 type 1 repeat	BPTI-like	1	1
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	1	1
RING/U-box	Protein kinase-like (PK-like)	1	1
Somatomedin B domain	TSP-1 type 1 repeat	1	1
ENTH/VHS domain	Periplasmic binding protein-like II	1	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Growth factor receptor domain	1	1
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
PH domain-like	Formin homology 2 domain (FH2 domain)	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
L domain-like	DNase I-like	1	1
RCC1/BLIP-II	RCC1/BLIP-II	1	1
ADP-ribosylation	ENTH/VHS domain	1	1
Calponin-homology domain, CH-domain	RING/U-box	1	1
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
FAD/NAD(P)-binding domain	Ankyrin repeat	1	1
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	1	1
IP3 receptor type 1 binding core, domain 2	Concanavalin A-like lectins/glucanases	1	1
HIT-like	HIT-like	1	1
WD40 repeat-like	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Cullin homology domain	PH domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
Thioredoxin-like	Cysteine proteinases	1	1
Ribonuclease PH domain 2-like	EF-hand	1	1
Spectrin repeat	RING/U-box	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
Bet v1-like	MIT domain	1	1
RING/U-box	CSL zinc finger	1	1
Notch domain	Notch domain	1	1
SNF-like	P-loop containing nucleoside triphosphate hydrolases	1	1
CCCH zinc finger	ISP transmembrane anchor	1	1
Smc hinge domain	Tropomyosin	1	1
Domain of poly(ADP-ribose) polymerase	Voltage-gated potassium channels	1	1
S-adenosyl-L-methionine-dependent methyltransferases	ITPase-like	1	1
Protein kinase-like (PK-like)	POZ domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
F-box domain	Sec7 domain	1	1
C-type lectin-like	Kringle-like	1	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	1	1
PH domain-like	NHL repeat	1	1
Ubiquitin-like	Cap-Gly domain	1	1
TPR-like	Chaperone J-domain	1	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	1	1
Plakin repeat	GAS2 domain-like	1	1
Retrovirus zinc finger-like domains	ISP transmembrane anchor	1	1
NTF2-like	UBA-like	1	1
RING/U-box	BRCT domain	1	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
Lipoxigenase	Lipoxigenase	1	1
SH2 domain	RING/U-box	1	1
Kix domain of CBP (creb binding protein)	FYVE/PHD zinc finger	1	1
Complement control module/SCR domain	Complement control module/SCR domain	1	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	1	1
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Ribokinase-like	1	1
Calponin-homology domain, CH-domain	SH3-domain	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VHP, Villin headpiece domain	1	1
DBL homology domain (DH-domain)	SH2 domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
vWA-like	C-terminal domain of Ku80	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
PH domain-like	PLC-like phosphodiesterases	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
Tropomyosin	FYVE/PHD zinc finger	1	1
L domain-like	Concanavalin A-like lectins/glucanases	1	1
RING/U-box	PX domain	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
alpha/beta-Hydrolases	TSP-1 type 1 repeat	1	1
GTPase activation domain, GAP	GTPase activation domain, GAP	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	1	1
L27 domain	P-loop containing nucleoside triphosphate hydrolases	1	1
TPR-like	Ankyrin repeat	1	1
RuvA domain 2-like	SH2 domain	1	1
Cullin homology domain	Protein kinase-like (PK-like)	1	1
Multidrug resistance efflux transporter EmrE	beta-Galactosidase/glucuronidase domain	1	1
RNA-binding domain, RBD	DBL homology domain (DH-domain)	1	1
Regulator of G-protein signaling, RGS	Cysteine-rich domain	1	1
Metallo-dependent phosphatases	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Protein kinase-like (PK-like)	Zn-dependent exopeptidases	1	1
Calpain large subunit, middle domain (domain III)	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Supernatant protein factor (SPF), C-terminal domain	Immunoglobulin	1	1
BRK domain-like	Bromodomain	1	1
PDZ domain-like	BAR/IMD domain-like	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	1	1
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
PUG domain-like	FYVE/PHD zinc finger	1	1
TPR-like	RNA-binding domain, RBD	1	1
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	1	1
Histone-fold	Macro domain-like	1	1
PH domain-like	BSD domain-like	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
Ubiquitin-like	Ran binding protein zinc finger-like	1	1
ARM repeat	SH3-domain	1	1
PGBD-like	Metalloproteases ("zincins"), catalytic domain	1	1
N-terminal domain of cbl (N-cbl)	EF-hand	1	1
SET domain	Homeodomain-like	1	1
vWA-like	Growth factor receptor domain	1	1
SH3-domain	SAM/Pointed domain	1	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
PH domain-like	Nucleotide-diphospho-sugar transferases	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Ankyrin repeat	SAM/Pointed domain	1	1
GckA/TtuD-like	GckA/TtuD-like	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
DBL homology domain (DH-domain)	Ras GEF	1	1
L domain-like	NTF2-like	1	1
BEACH domain	FYVE/PHD zinc finger	1	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	1	1
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	1	1
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
Nucleotidylyl transferase	Class II aaRS ABD-related	1	1
vWA-like	TSP-1 type 1 repeat	1	1
PH domain-like	Bet v1-like	1	1
Nucleic acid-binding proteins	TPR-like	1	1
FYVE/PHD zinc finger	"Winged helix" DNA-binding domain	1	1
Nucleotidylyl transferase	C-terminal domain of ProRS	1	1
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	1	1
Mib/herc2 domain-like	Ankyrin repeat	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	1	1
RUN domain-like	Tropomyosin	1	1
Mannose 6-phosphate receptor domain	Oxysterol-binding protein-like	1	1
EF-hand	Translation proteins SH3-like domain	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Cation efflux protein cytoplasmic domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
TPR-like	Metallo-dependent phosphatases	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
vWA-like	Nucleic acid-binding proteins	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
SAP domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Trefoil	(Trans)glycosidases	1	1
Clavaminate synthase-like	Tudor/PWWP/MBT	1	1
Ribosomal protein S5 domain 2-like	TSP-1 type 1 repeat	1	1
Sec1/munc18-like (SM) proteins	Sec1/munc18-like (SM) proteins	1	1
CalX-like	C-type lectin-like	1	1
EGF/Laminin	ARM repeat	1	1
DBL homology domain (DH-domain)	Fibronectin type III	1	1
UBA-like	KA1-like	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
EF-hand	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Tricorn protease domain 2	WD40 repeat-like	1	1
L domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
RNI-like	UBC-like	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Protein kinase-like (PK-like)	L27 domain	1	1
Ligand-binding domain in the NO signalling and Golgi transport	FYVE/PHD zinc finger	1	1
L domain-like	Heme-dependent peroxidases	1	1
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	1	1
Protease propeptides/inhibitors	Subtilisin-like	1	1
PUG domain-like	Galactose-binding domain-like	1	1
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	1	1
LDL receptor-like module	Mannose 6-phosphate receptor domain	1	1
Supernatant protein factor (SPF), C-terminal domain	LDL receptor-like module	1	1
Fibronectin type III	Cyclin-like	1	1
FAD-dependent thiol oxidase	Sm-like ribonucleoproteins	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Frizzled cysteine-rich domain	TIMP-like	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Ribosomal protein L4	Ribosomal protein L4	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
EF-hand	C-terminal domain of PLC-beta	1	1
Band 7/SPFH domain	PAZ domain	1	1
Chaperone J-domain	ARM repeat	1	1
BRCT domain	DBL homology domain (DH-domain)	1	1
N-terminal domain of cbl (N-cbl)	RING/U-box	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
DNA clamp	DNA clamp	1	1
Ypt/Rab-GAP domain of gyp1p	SH3-domain	1	1
PUG domain-like	Protein kinase-like (PK-like)	1	1
FMN-linked oxidoreductases	dsRNA-binding domain-like	1	1
GST C-terminal domain-like	Class II aaRS and biotin synthetases	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Cation efflux protein transmembrane domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Formin homology 2 domain (FH2 domain)	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	1	1
PX domain	Protein kinase-like (PK-like)	1	1
YWTD domain	YWTD domain	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
RNA-binding domain, RBD	PH domain-like	1	1
Protein kinase-like (PK-like)	UBA-like	1	1
Tudor/PWWP/MBT	BRCT domain	1	1
Flavoproteins	Riboflavin synthase domain-like	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
DNA/RNA polymerases	Immunoglobulin	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
Polo-box domain	Kelch motif	1	1
Thioredoxin-like	PUG domain-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Bromodomain	HLH, helix-loop-helix DNA-binding domain	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
WGR domain-like	Voltage-gated potassium channels	1	1
CAD & PB1 domains	PDZ domain-like	1	1
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	1	1
SH3-domain	RUN domain-like	1	1
vWA-like	BRCA2 helical domain	1	1
Ankyrin repeat	SOCS box-like	1	1
Zn-dependent exopeptidases	ARM repeat	1	1
Plus3-like	Restriction endonuclease-like	1	1
DNA-binding domain	FYVE/PHD zinc finger	1	1
EF-hand	GAS2 domain-like	1	1
Cullin homology domain	ARM repeat	1	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	1	1
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	1	1
L domain-like	SAM/Pointed domain	1	1
Rof/RNase P subunit-like	EF-hand	1	1
Ankyrin repeat	Eukaryotic type KH-domain (KH-domain type I)	1	1
Adenine nucleotide alpha hydrolases-like	Cation efflux protein transmembrane domain-like	1	1
MIT domain	Cysteine proteinases	1	1
Kelch motif	Fibronectin type III	1	1
UBA-like	UBA-like	1	1
Growth factor receptor domain	Notch domain	1	1
Ubiquitin-like	The spindle assembly checkpoint protein mad2	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Cysteine-rich domain	PH domain-like	1	1
TATA-box binding protein-like	Zn-binding ribosomal proteins	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Cation efflux protein transmembrane domain-like	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
B-box zinc-binding domain	TRAF domain-like	1	1
Spectrin repeat	Plakin repeat	1	1
Metallo-dependent phosphatases	SAICAR synthase-like	1	1
vWA-like	Cysteine-rich domain	1	1
DUSP-like	DUSP-like	1	1
Ankyrin repeat	SH3-domain	1	1
Regulator of G-protein signaling, RGS	Nucleic acid-binding proteins	1	1
Actin-like ATPase domain	AF1104-like	1	1
Nucleotide-diphospho-sugar transferases	Seven-hairpin glycosidases	1	1
Putative DNA-binding domain	Cation efflux protein transmembrane domain-like	1	1
(Phosphotyrosine protein) phosphatases II	Chaperone J-domain	1	1
DNase I-like	GTPase activation domain, GAP	1	1
Spermadhesin, CUB domain	LDL receptor-like module	1	1
Family A G protein-coupled receptor-like	Nucleotide-diphospho-sugar transferases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	1	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	1	1
N-terminal domain of cbl (N-cbl)	SH2 domain	1	1
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Metallo-dependent phosphatases	1	1
Voltage-gated potassium channels	EF-hand	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	1	1
Outer arm dynein light chain 1	Tropomyosin	1	1
Prokaryotic ribosomal protein L17	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
PapD-like	PapD-like	1	1
RING/U-box	Fibronectin type III	1	1
Plexin repeat	E set domains	1	1
RNI-like	RNI-like	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
P-loop containing nucleoside triphosphate hydrolases	EGF/Laminin	1	1
ISP transmembrane anchor	ISP domain	1	1
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	1	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	1	1
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	1	1
DNA-binding domain	SET domain	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	1	1
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	1	1
Cysteine proteinases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Ankyrin repeat	ADP-ribosylation	1	1
P-loop containing nucleoside triphosphate hydrolases	eIF4e-like	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
WD40 repeat-like	Peptidase/esterase 'gauge' domain	1	1
PA domain	Zn-dependent exopeptidases	1	1
ClpP/crotonase	Kelch motif	1	1
RING/U-box	MFS general substrate transporter	1	1
HMA, heavy metal-associated domain	HAD-like	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
Trefoil	Glycosyl hydrolase domain	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Ribonuclease H-like	HRDC-like	1	1
Ribosomal protein L25-like	Class II aaRS ABD-related	1	1
CCCH zinc finger	Rhodanese/Cell cycle control phosphatase	1	1
CCCH zinc finger	Retrovirus zinc finger-like domains	1	1
ARM repeat	L domain-like	1	1
FF domain	SMAD/FHA domain	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
Multidrug resistance efflux transporter EmrE	(Trans)glycosidases	1	1
L27 domain	L27 domain	1	1
CCCH zinc finger	Chaperone J-domain	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
PUG domain-like	Ubiquitin-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	1	1
Trypsin-like serine proteases	Trypsin-like serine proteases	1	1
Actin-like ATPase domain	SNARE fusion complex	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
SAM/Pointed domain	PH domain-like	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
beta-beta-alpha zinc fingers	Ribonuclease H-like	1	1
"Winged helix" DNA-binding domain	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
beta-beta-alpha zinc fingers	Voltage-gated potassium channels	1	1
vWA-like	Immunoglobulin	1	1
C-terminal autoproteolytic domain of nucleoporin nup98	Creatinase/aminopeptidase	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
CCCH zinc finger	RING/U-box	1	1
Regulator of G-protein signaling, RGS	PX domain	1	1
DEATH domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Prokaryotic ribosomal protein L17	ValRS/IleRS/LeuRS editing domain	1	1
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	1	1
IP3 receptor type 1 binding core, domain 2	EF-hand	1	1
DNA-binding domain	Bromodomain	1	1
Domain of poly(ADP-ribose) polymerase	Periplasmic binding protein-like II	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	1	1
UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
ADP-ribosylation	Periplasmic binding protein-like I	1	1
Cadherin-like	EGF/Laminin	1	1
TSP-1 type 1 repeat	GFP-like	1	1
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	1	1
(Phosphotyrosine protein) phosphatases II	Cyclin-like	1	1
RUN domain-like	RUN domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
MIR domain	EF-hand	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	1	1
C-terminal autoproteolytic domain of nucleoporin nup98	Creatinase/prolidase N-terminal domain	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
Ribonuclease PH domain 2-like	alpha/beta-Hydrolases	1	1
PLP-dependent transferases	ARM repeat	1	1
t-snare proteins	SNARE fusion complex	1	1
Metallo-dependent phosphatases	"Winged helix" DNA-binding domain	1	1
PUA domain-like	Ribosomal protein S5 domain 2-like	1	1
Galactose-binding domain-like	EGF/Laminin	1	1
Translational machinery components	alpha/beta-Hydrolases	1	1
GST C-terminal domain-like	C-terminal domain of ProRS	1	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	1	1
Mannose 6-phosphate receptor domain	PH domain-like	1	1
Dcp2 domain-like	Nudix	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
Polo-box domain	WD40 repeat-like	1	1
POZ domain	Alpha-L RNA-binding motif	1	1
Calponin-homology domain, CH-domain	Plakin repeat	1	1
NAD(P)-binding Rossmann-fold domains	Clavaminate synthase-like	1	1
FYVE/PHD zinc finger	PDZ domain-like	1	1
SAND domain-like	Ran binding protein zinc finger-like	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
Neurotransmitter-gated ion-channel transmembrane pore	RmlC-like cupins	1	1
Polo-box domain	EF-hand	1	1
TATA-box binding protein-like	C-terminal domain of alpha and beta subunits of F1 ATP synthase	1	1
Retrovirus zinc finger-like domains	RING/U-box	1	1
Acid proteases	Ribonuclease H-like	1	1
PDZ domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
DNA repair protein MutS, domain III	DNA repair protein MutS, domain III	1	1
Sema domain	TSP-1 type 1 repeat	1	1
Polo-box domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
RING/U-box	YWTD domain	1	1
BRCT domain	Homeodomain-like	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
RING/U-box	Immunoglobulin	1	1
Acyl-CoA N-acyltransferases (Nat)	EGF/Laminin	1	1
Regulator of G-protein signaling, RGS	PH domain-like	1	1
Nuclear receptor ligand-binding domain	Nuclear receptor ligand-binding domain	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
Cysteine-rich domain	SAM/Pointed domain	1	1
Leucine zipper domain	Leucine zipper domain	1	1
Metallo-hydrolase/oxidoreductase	beta-beta-alpha zinc fingers	1	1
DEATH domain	WD40 repeat-like	1	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	1	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Metallo-dependent phosphatases	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
Cullin repeat-like	ARM repeat	1	1
I/LWEQ domain	alpha-catenin/vinculin-like	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
Ankyrin repeat	L domain-like	1	1
Ubiquitin-like	Ankyrin repeat	1	1
Multidrug resistance efflux transporter EmrE	Galactose-binding domain-like	1	1
Calponin-homology domain, CH-domain	WW domain	1	1
TSP-1 type 1 repeat	Growth factor receptor domain	1	1
SWIB/MDM2 domain	eIF1-like	1	1
beta-beta-alpha zinc fingers	Ankyrin repeat	1	1
UBA-like	DNase I-like	1	1
Ubiquitin-like	FYVE/PHD zinc finger	1	1
RNA-binding domain, RBD	SET domain	1	1
E set domains	NHL repeat	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
Metallo-dependent phosphatases	EF-hand	1	1
Spectrin repeat	Immunoglobulin	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
Plexin repeat	GTPase activation domain, GAP	1	1
Galactose-binding domain-like	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
Cap-Gly domain	L domain-like	1	1
GST C-terminal domain-like	eEF-1beta-like	1	1
WW domain	SMAD/FHA domain	1	1
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
HR1 repeat	Protein kinase-like (PK-like)	1	1
B-box zinc-binding domain	Fibronectin type III	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
RING/U-box	UBA-like	1	1
SH2 domain	Trm112p-like	1	1
Putative DNA-binding domain	Ran binding protein zinc finger-like	1	1
Immunoglobulin	alpha/beta-Hydrolases	1	1
Hedgehog/DD-peptidase	Hedgehog/DD-peptidase	1	1
PGBD-like	Hemopexin-like domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	WD40 repeat-like	1	1
TPR-like	Protein prenylyltransferase	1	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	1	1
BEACH domain	NHL repeat	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Concanavalin A-like lectins/glucanases	EF-hand	1	1
MIR domain	MIR domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
vWA-like	SAP domain	1	1
Cullin homology domain	Second domain of FERM	1	1
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	1	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	1	1
Sema domain	GTPase activation domain, GAP	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Suppressor of Fused, N-terminal domain	Suppressor of Fused, N-terminal domain	1	1
Cullin homology domain	Moesin tail domain	1	1
P-loop containing nucleoside triphosphate hydrolases	WW domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Actin depolymerizing proteins	VHP, Villin headpiece domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
Plakin repeat	EF-hand	1	1
CCCH zinc finger	ISP domain	1	1
Sm-like ribonucleoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
POZ domain	Galactose-binding domain-like	1	1
RNA-binding domain, RBD	PX domain	1	1
Ubiquitin-like	Moesin tail domain	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Ankyrin repeat	RNI-like	1	1
RNA-binding domain, RBD	dsRNA-binding domain-like	1	1
Ribonuclease H-like	Phosphoglucomutase, first 3 domains	1	1
alpha/beta-Hydrolases	Nop domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
EGF/Laminin	TB module/8-cys domain	1	1
WW domain	RING/U-box	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
PAH2 domain	PAH2 domain	1	1
Metallo-dependent phosphatases	GroEL apical domain-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
Chromo domain-like	Ankyrin repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	RNI-like	1	1
Cation efflux protein cytoplasmic domain-like	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	1	1
BAR/IMD domain-like	Protein kinase-like (PK-like)	1	1
Protein kinase-like (PK-like)	A DNA-binding domain in eukaryotic transcription factors	1	1
vWA-like	GFP-like	1	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	1	1
cAMP-binding domain-like	FabD/lysophospholipase-like	1	1
Periplasmic binding protein-like I	Nucleotide cyclase	1	1
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	1	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	1	1
SAICAR synthase-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
GST C-terminal domain-like	Class II aaRS ABD-related	1	1
Nicotinic receptor ligand binding domain-like	RmlC-like cupins	1	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	1	1
Metal cation-transporting ATPase, ATP-binding domain N	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
Bromodomain	HMG-box	1	1
EF-hand	Kelch motif	1	1
Phosphofructokinase	Phosphofructokinase	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	P-loop containing nucleoside triphosphate hydrolases	1	1
RING/U-box	Rnp2-like	1	1
Retrovirus zinc finger-like domains	ISP domain	1	1
SMAD/FHA domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
"Winged helix" DNA-binding domain	occludin/ELL-like	1	1
PRP4-like	WD40 repeat-like	1	1
SMAD/FHA domain	Zinc beta-ribbon	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
Terpenoid synthases	Restriction endonuclease-like	1	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	1	1
WW domain	FKBP-like	1	1
Hedgehog/DD-peptidase	Hedgehog/intein (Hint) domain	1	1
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	1	1
Protein kinase-like (PK-like)	EF-hand	1	1
"Winged helix" DNA-binding domain	GroEL apical domain-like	1	1
SET domain	beta-beta-alpha zinc fingers	1	1
Thioredoxin-like	FAD/NAD(P)-binding domain	1	1
EGF/Laminin	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
SMAD/FHA domain	Elongation factor TFIIS domain 2	1	1
eIF4e-like	Protein kinase-like (PK-like)	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Ribosomal protein L1	WD40 repeat-like	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Polo-box domain	POZ domain	1	1
UBA-like	XPC-binding domain	1	1
Fibronectin type III	SH3-domain	1	1
Band 7/SPFH domain	Ribonuclease H-like	1	1
beta-beta-alpha zinc fingers	WW domain	1	1
GST C-terminal domain-like	GST C-terminal domain-like	1	1
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	1	1
SPOC domain-like	SAP domain	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	Kelch motif	1	1
Thioredoxin-like	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
WD40 repeat-like	Glycolipid transfer protein, GLTP	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
DEATH domain	Caspase-like	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
Seven-hairpin glycosidases	PA domain	1	1
Nudix	DNase I-like	1	1
Ribosomal protein L25-like	C-terminal domain of ProRS	1	1
Radical SAM enzymes	LDL receptor-like module	1	1
ENTH/VHS domain	Periplasmic binding protein-like I	1	1
E set domains	(Trans)glycosidases	1	1
ADP-ribosylation	Periplasmic binding protein-like II	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
PurM N-terminal domain-like	PurM C-terminal domain-like	1	1
Cullin repeat-like	Protein kinase-like (PK-like)	1	1
Acyl-CoA binding protein	Supernatant protein factor (SPF), C-terminal domain	1	1
Starch-binding domain-like	PLC-like phosphodiesterases	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Mitochondrial carrier	Glutathione synthetase ATP-binding domain-like	1	1
WD40 repeat-like	LanC-like	1	1
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
FAD/NAD(P)-binding domain	EF-hand	1	1
PDZ domain-like	Cysteine-rich domain	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
SNARE fusion complex	RING/U-box	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
Spectrin repeat	GAS2 domain-like	1	1
vWA-like	EGF/Laminin	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Ankyrin repeat	Immunoglobulin	1	1
Ribonuclease H-like	Phosphoglucomutase, C-terminal domain	1	1
WW domain	EF-hand	1	1
SAM/Pointed domain	ADP-ribosylation	1	1
mRNA decapping enzyme DcpS N-terminal domain	HIT-like	1	1
Chaperone J-domain	E set domains	1	1
HAD-like	MIT domain	1	1
L9 N-domain-like	Phosphoglucomutase, C-terminal domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	NAD(P)-binding Rossmann-fold domains	1	1
GAF domain-like	HD-domain/PDEase-like	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
SH2 domain	Ankyrin repeat	1	1
MIR domain	Concanavalin A-like lectins/glucanases	1	1
Ribonuclease H-like	SMAD/FHA domain	1	1
Metallo-hydrolase/oxidoreductase	UBC-like	1	1
Carbon-nitrogen hydrolase	HIT-like	1	1
TPR-like	Band 7/SPFH domain	1	1
Galactose-binding domain-like	Protein kinase-like (PK-like)	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Putative DNA-binding domain	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
Cation efflux protein transmembrane domain-like	Homeodomain-like	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Ypt/Rab-GAP domain of gyp1p	WD40 repeat-like	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Ubiquitin-like	Zn-binding ribosomal proteins	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
Fibronectin type III	Ankyrin repeat	1	1
Cysteine proteinases	Proton glutamate symport protein	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Ankyrin repeat	Cap-Gly domain	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Terpenoid synthases	RuvA domain 2-like	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Translation proteins	Histone-fold	1	1
Ribonuclease PH domain 2-like	TSP-1 type 1 repeat	1	1
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	1	1
PDZ domain-like	GTPase activation domain, GAP	1	1
SMAD/FHA domain	PH domain-like	1	1
Calponin-homology domain, CH-domain	SH2 domain	1	1
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	1	1
BPTI-like	Tricorn protease domain 2	1	1
PH domain-like	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	1	1
EF-hand	Glutathione synthetase ATP-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	1	1
L domain-like	UBA-like	1	1
vWA-like	BRCA2 tower domain	1	1
beta-beta-alpha zinc fingers	Growth factor receptor domain	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
FYVE/PHD zinc finger	Rabenosyn-5 Rab-binding domain-like	1	1
ClpP/crotonase	ClpP/crotonase	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
GroEL apical domain-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Hypothetical protein PA1324	Carboxypeptidase regulatory domain-like	1	1
FAD-linked reductases, C-terminal domain	Ankyrin repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	1	1
SET domain	WW domain	1	1
CalX-like	CalX-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
MIR domain	IP3 receptor type 1 binding core, domain 2	1	1
PH domain-like	HMG-box	1	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	1	1
Protein kinase-like (PK-like)	Rhodanese/Cell cycle control phosphatase	1	1
PreATP-grasp domain	Single hybrid motif	1	1
NAD(P)-binding Rossmann-fold domains	Immunoglobulin	1	1
Ribosomal protein S5 domain 2-like	Nop domain	1	1
NAD(P)-binding Rossmann-fold domains	LDL receptor-like module	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
Tudor/PWWP/MBT	HIT/MYND zinc finger-like	1	1
Periplasmic binding protein-like I	Periplasmic binding protein-like I	1	1
TPR-like	PIN domain-like	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
Ankyrin repeat	Nucleotide-diphospho-sugar transferases	1	1
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	1	1
Putative isomerase YbhE	WD40 repeat-like	1	1
HAD-like	HAD-like	1	1
Class II aaRS ABD-related	C-terminal domain of ProRS	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
TSP-1 type 1 repeat	Nop domain	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Ankyrin repeat	Caspase-like	1	1
TAZ domain	FYVE/PHD zinc finger	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
Acetyl-CoA synthetase-like	ACP-like	1	1
WW domain	PH domain-like	1	1
Immunoglobulin	GFP-like	1	1
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	1	1
TRAF domain-like	POZ domain	1	1
GFP-like	EGF/Laminin	1	1
BRCT domain	DNA/RNA polymerases	1	1
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	1	1
Fibronectin type III	Multiheme cytochromes	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
Kringle-like	Kringle-like	1	1
E set domains	Glycosyl hydrolase domain	1	1
PH domain-like	Ypt/Rab-GAP domain of gyp1p	1	1
Immunoglobulin	Calponin-homology domain, CH-domain	1	1
Putative methyltransferase TM0872, insert domain	WD40 repeat-like	1	1
BEACH domain	Putative isomerase YbhE	1	1
BPTI-like	Immunoglobulin	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	1	1
EF-hand	Rhomboid-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	RNA-binding domain, RBD	1	1
Plexin repeat	vWA-like	1	1
FYVE/PHD zinc finger	SAM/Pointed domain	1	1
Prokaryotic ribosomal protein L17	Nucleotidylyl transferase	1	1
BAR/IMD domain-like	Ankyrin repeat	1	1
Tudor/PWWP/MBT	Ubiquitin-like	1	1
lambda repressor-like DNA-binding domains	lambda repressor-like DNA-binding domains	1	1
Fibronectin type III	Concanavalin A-like lectins/glucanases	1	1
ENTH/VHS domain	RNA-binding domain, RBD	1	1
"Winged helix" DNA-binding domain	Second domain of FERM	1	1
TB module/8-cys domain	Growth factor receptor domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
TPR-like	Ribosomal protein S10	1	1
DBL homology domain (DH-domain)	Immunoglobulin	1	1
"Winged helix" DNA-binding domain	PRC-barrel domain	1	1
Adenine nucleotide alpha hydrolases-like	Putative DNA-binding domain	1	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	POZ domain	1	1
Galactose-binding domain-like	BRCT domain	1	1
Saposin	Saposin	1	1
ARID-like	Chromo domain-like	1	1
Rof/RNase P subunit-like	Calpain large subunit, middle domain (domain III)	1	1
Chaperone J-domain	Phosphoenolpyruvate/pyruvate domain	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
TPR-like	ARM repeat	1	1
Growth factor receptor domain	Ankyrin repeat	1	1
Chromo domain-like	EGF/Laminin	1	1
Cation efflux protein cytoplasmic domain-like	Homeodomain-like	1	1
L domain-like	WD40 repeat-like	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Sema domain	E set domains	1	1
Protease propeptides/inhibitors	Zn-dependent exopeptidases	1	1
beta-beta-alpha zinc fingers	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	beta-beta-alpha zinc fingers	1	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Tudor/PWWP/MBT	SET domain	1	1
EGF/Laminin	TIMP-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Chaperone J-domain	1	1
Translation proteins	Translation proteins	1	1
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Rudiment single hybrid motif	Single hybrid motif	1	1
RUN domain-like	PH domain-like	1	1
FKBP-like	FKBP-like	1	1
L domain-like	Actin depolymerizing proteins	1	1
Spectrin repeat	DBL homology domain (DH-domain)	1	1
Chaperone J-domain	CSL zinc finger	1	1
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	1	1
SH2 domain	WD40 repeat-like	1	1
PDZ domain-like	WW domain	1	1
Voltage-gated potassium channels	Small-conductance potassium channel	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
Rof/RNase P subunit-like	Cysteine proteinases	1	1
ARM repeat	Hect, E3 ligase catalytic domain	1	1
TRAF domain-like	Cysteine proteinases	1	1
PH domain-like	Putative isomerase YbhE	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
beta-lactamase/transpeptidase-like	Thioredoxin-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
ArfGap/RecO-like zinc finger	Nucleotide-diphospho-sugar transferases	1	1
P-loop containing nucleoside triphosphate hydrolases	Cysteine proteinases	1	1
DBL homology domain (DH-domain)	Protein kinase-like (PK-like)	1	1
PX domain	RNI-like	1	1
TATA-box binding protein-like	N-terminal domain of alpha and beta subunits of F1 ATP synthase	1	1
Trefoil	Galactose mutarotase-like	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
EF-hand	PLC-like phosphodiesterases	1	1
Translational machinery components	Coiled-coil domain of nucleotide exchange factor GrpE	1	1
UBC-like	UBA-like	1	1
alpha/beta-Hydrolases	EF-hand	1	1
Tex N-terminal region-like	SH2 domain	1	1
BAR/IMD domain-like	Nucleotide-diphospho-sugar transferases	1	1
PLP-dependent transferases	Adenine nucleotide alpha hydrolases-like	1	1
PH domain-like	C-terminal domain of PLC-beta	1	1
L domain-like	RING/U-box	1	1
Molybdenum cofactor biosynthesis proteins	Adenine nucleotide alpha hydrolases-like	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	1	1
Spectrin repeat	WW domain	1	1
Immunoglobulin	Tricorn protease domain 2	1	1
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	1	1
EF-hand	SH2 domain	1	1
Polo-box domain	Polo-box domain	1	1
GTPase activation domain, GAP	SH3-domain	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
WD40 repeat-like	Bromodomain	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	1	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	1	1
TRAF domain-like	TRAF domain-like	1	1
Ribonuclease H-like	SH2 domain	1	1
tRNA-binding arm	Class II aaRS and biotin synthetases	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Thiamin diphosphate-binding fold (THDP-binding)	1	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	1	1
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	1	1
Protein kinase-like (PK-like)	FYVE/PHD zinc finger	1	1
TPR-like	RNI-like	1	1
TROVE domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
TPR-like	Clavaminate synthase-like	1	1
POZ domain	Mannose-binding lectins	1	1
L27 domain	SH3-domain	1	1
Ubiquitin-like	HAD-like	1	1
WW domain	BAG domain	1	1
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	1	1
WD40 repeat-like	Kelch motif	1	1
WD40 repeat-like	UBC-like	1	1
L9 N-domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
vWA-like	WD40 repeat-like	1	1
PUG domain-like	Cysteine proteinases	1	1
BSD domain-like	BSD domain-like	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
Spectrin repeat	SH3-domain	1	1
TATA-box binding protein-like	P-loop containing nucleoside triphosphate hydrolases	1	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	1	1
Ribosomal protein S5 domain 2-like	EF-hand	1	1
MAST3 pre-PK domain-like	PDZ domain-like	1	1
RNA-binding domain, RBD	Tryptophan synthase beta subunit-like PLP-dependent enzymes	1	1
ENTH/VHS domain	Voltage-gated potassium channels	1	1