Domain combination pairs in Anopheles gambiae 49_3j

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1799 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	217	86
Immunoglobulin	Immunoglobulin	115	56
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	101	40
Trypsin-like serine proteases	Trypsin-like serine proteases	51	9
Glucocorticoid receptor-like (DNA-binding domain)	beta-beta-alpha zinc fingers	49	20
Invertebrate chitin-binding proteins	Invertebrate chitin-binding proteins	46	25
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	44	8
RNA-binding domain, RBD	RNA-binding domain, RBD	44	20
Immunoglobulin	Fibronectin type III	42	31
Thioredoxin-like	GST C-terminal domain-like	39	3
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	37	8
L domain-like	L domain-like	37	32
Cadherin-like	Cadherin-like	36	30
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	34	22
TPR-like	TPR-like	32	19
EGF/Laminin	EGF/Laminin	32	31
Actin-like ATPase domain	Actin-like ATPase domain	30	12
Fibronectin type III	Fibronectin type III	29	25
DBL homology domain (DH-domain)	PH domain-like	27	19
ARM repeat	ARM repeat	26	16
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	24	23
POZ domain	beta-beta-alpha zinc fingers	23	5
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	23	3
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	22	8
Voltage-gated potassium channels	Voltage-gated potassium channels	22	10
Ankyrin repeat	Ankyrin repeat	20	15
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	20	7
Homeodomain-like	Homeodomain-like	20	13
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	19	8
(Trans)glycosidases	Chitinase insertion domain	19	7
E set domains	E set domains	19	11
Cadherin-like	Concanavalin A-like lectins/glucanases	18	13
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	18	5
PDZ domain-like	PDZ domain-like	18	15
Insect pheromone/odorant-binding proteins	Insect pheromone/odorant-binding proteins	18	3
HIT/MYND zinc finger-like	SET domain	18	5
LDL receptor-like module	LDL receptor-like module	17	17
EF-hand	EF-hand	17	15
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	17	9
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	17	1
WD40 repeat-like	WD40 repeat-like	17	9
TPR-like	SET domain	16	3
GroES-like	NAD(P)-binding Rossmann-fold domains	16	6
PH domain-like	PH domain-like	16	13
Second domain of FERM	PH domain-like	16	11
Calcium ATPase, transduction domain A	HAD-like	16	5
TPR-like	HIT/MYND zinc finger-like	16	3
F-box domain	RNI-like	16	5
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	16	10
Cyclin-like	Cyclin-like	16	6
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	16	5
HAD-like	Calcium ATPase, transmembrane domain M	16	5
Growth factor receptor domain	EGF/Laminin	16	16
Growth factor receptor domain	Growth factor receptor domain	16	16
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	15	5
Hemocyanin, N-terminal domain	E set domains	15	3
Concanavalin A-like lectins/glucanases	EGF/Laminin	15	15
PDZ domain-like	PH domain-like	14	11
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	14	4
Ubiquitin-like	PH domain-like	14	9
Protease propeptides/inhibitors	Zn-dependent exopeptidases	14	1
BAR/IMD domain-like	SH3-domain	14	7
SH3-domain	PH domain-like	14	12
Di-copper centre-containing domain	E set domains	14	3
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	14	4
ARM repeat	Protein kinase-like (PK-like)	13	11
Hemocyanin, N-terminal domain	Di-copper centre-containing domain	13	2
Thioredoxin-like	Thioredoxin-like	13	9
(Trans)glycosidases	Glycosyl hydrolase domain	13	5
Ubiquitin-like	Second domain of FERM	13	8
ABC transporter transmembrane region	ABC transporter transmembrane region	12	5
SH3-domain	SH3-domain	12	10
C2 domain (Calcium/lipid-binding domain, CaLB)	PH domain-like	12	10
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	12	3
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	12	9
Ubiquitin-like	Ubiquitin-like	12	9
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	11	9
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	11	5
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	11	6
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	11	6
L domain-like	Toll/Interleukin receptor TIR domain	11	11
SH3-domain	SH2 domain	11	9
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	11	3
Periplasmic binding protein-like I	Periplasmic binding protein-like II	10	5
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	10	5
TSP-1 type 1 repeat	TSP-1 type 1 repeat	10	10
cAMP-binding domain-like	cAMP-binding domain-like	10	7
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	10	5
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	10	2
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	10	7
GroEL equatorial domain-like	GroEL-intermediate domain like	10	2
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	10	9
RING/U-box	RING/U-box	10	7
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	10	7
PH domain-like	(Phosphotyrosine protein) phosphatases II	10	8
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	10	3
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	10	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	9	1
GroEL equatorial domain-like	GroEL apical domain-like	9	1
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	9	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	9	1
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	9	3
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	9	7
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	9	6
Voltage-gated potassium channels	cAMP-binding domain-like	9	2
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	9	1
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	9	1
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	9	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	9	8
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	9	1
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	9	1
GroEL-intermediate domain like	GroEL apical domain-like	9	1
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	9	7
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	9	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	9	1
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	9	1
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	9	1
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	9	1
WW domain	WW domain	9	8
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	9	1
FYVE/PHD zinc finger	FYVE/PHD zinc finger	9	8
Spectrin repeat	Spectrin repeat	9	9
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	9	5
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	9	1
Complement control module/SCR domain	Complement control module/SCR domain	8	8
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	8	3
Cysteine-rich domain	Protein kinase-like (PK-like)	8	8
SH2 domain	Protein kinase-like (PK-like)	8	6
Nucleotide cyclase	Nucleotide cyclase	8	4
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	8	8
SH3-domain	DBL homology domain (DH-domain)	8	7
Concanavalin A-like lectins/glucanases	Growth factor receptor domain	8	8
PH domain-like	Protein kinase-like (PK-like)	8	8
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	8	4
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	4
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	8	6
Spermadhesin, CUB domain	Spermadhesin, CUB domain	8	8
GTPase activation domain, GAP	PH domain-like	8	6
Protein kinase-like (PK-like)	C2 domain (Calcium/lipid-binding domain, CaLB)	8	8
Actin depolymerizing proteins	Actin depolymerizing proteins	7	5
RING/U-box	B-box zinc-binding domain	7	6
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	7	5
Cupredoxins	Cupredoxins	7	4
LDL receptor-like module	YWTD domain	7	7
Guanido kinase N-terminal domain	Glutamine synthetase/guanido kinase	7	2
Thyroglobulin type-1 domain	Thyroglobulin type-1 domain	7	6
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	7	5
Nucleic acid-binding proteins	Nucleic acid-binding proteins	7	7
L domain-like	Immunoglobulin	7	5
SH2 domain	SH2 domain	7	7
PDZ domain-like	SH3-domain	7	7
Thiolase-like	Thiolase-like	7	3
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	7	7
POZ domain	Kelch motif	7	6
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	7	2
LDL receptor-like module	EGF/Laminin	7	7
LDL receptor-like module	Trypsin-like serine proteases	7	7
Fibronectin type III	Protein kinase-like (PK-like)	7	6
Protein kinase-like (PK-like)	SH3-domain	7	5
(Trans)glycosidases	Invertebrate chitin-binding proteins	7	5
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex, superhelical domain	7	3
Cysteine-rich domain	Cysteine-rich domain	7	7
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	7	6
Cadherin-like	EGF/Laminin	7	7
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	6	2
Chitinase insertion domain	Invertebrate chitin-binding proteins	6	4
POZ domain	Voltage-gated potassium channels	6	2
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	6	2
YWTD domain	YWTD domain	6	6
ARM repeat	WD40 repeat-like	6	5
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	6	5
Ubiquitin-like	UBA-like	6	5
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	6	5
Sema domain	Plexin repeat	6	4
POZ domain	Homeodomain-like	6	4
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	6	4
Myosin rod fragments	Myosin rod fragments	6	5
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	6	2
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	6	2
LDL receptor-like module	Spermadhesin, CUB domain	6	6
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	6	4
PreATP-grasp domain	Rudiment single hybrid motif	6	4
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	6	1
PH domain-like	SH2 domain	6	6
L27 domain	PDZ domain-like	6	6
FnI-like domain	FnI-like domain	6	6
Cullin homology domain	"Winged helix" DNA-binding domain	6	3
Spermadhesin, CUB domain	Trypsin-like serine proteases	6	2
Voltage-gated potassium channels	E set domains	6	3
RING/U-box	TRAF domain-like	6	5
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	6	5
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	6	2
L domain-like	RNI-like	6	6
PDZ domain-like	DBL homology domain (DH-domain)	6	4
Protein kinase-like (PK-like)	Nucleotide cyclase	6	4
EGF/Laminin	YWTD domain	6	6
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	6	3
FYVE/PHD zinc finger	Bromodomain	6	6
RNI-like	RNI-like	6	6
MFS general substrate transporter	MFS general substrate transporter	6	5
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	6	3
Kelch motif	Kelch motif	6	5
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	5	3
PH domain-like	ArfGap/RecO-like zinc finger	5	4
SAM/Pointed domain	SAM/Pointed domain	5	3
SAM/Pointed domain	ARM repeat	5	2
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	5	3
RING/U-box	Cysteine proteinases	5	4
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	4
ARM repeat	Formin homology 2 domain (FH2 domain)	5	3
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	5	5
Periplasmic binding protein-like I	Nucleotide cyclase	5	3
RING/U-box	WD40 repeat-like	5	5
PreATP-grasp domain	Single hybrid motif	5	3
Calponin-homology domain, CH-domain	Spectrin repeat	5	5
PLP-binding barrel	Alanine racemase C-terminal domain-like	5	2
Snake toxin-like	Protein kinase-like (PK-like)	5	3
PDZ domain-like	Ubiquitin-like	5	5
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	5	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	4
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	5	3
Invertebrate chitin-binding proteins	Glycoside hydrolase/deacetylase	5	5
lambda repressor-like DNA-binding domains	Homeodomain-like	5	2
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	5	3
PHM/PNGase F	PHM/PNGase F	5	2
Translation proteins	EF-G C-terminal domain-like	5	3
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	5	1
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	5	4
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	5	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	5	5
EGF/Laminin	Spermadhesin, CUB domain	5	5
PAZ domain	Ribonuclease H-like	5	2
MFS general substrate transporter	Kazal-type serine protease inhibitors	5	4
Chromo domain-like	Chromo domain-like	5	5
Cysteine-rich domain	PH domain-like	5	5
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	5	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	5	3
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	5	5
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	5	5
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	5	2
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	5	5
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	5	2
dsRNA-binding domain-like	dsRNA-binding domain-like	5	5
ArfGap/RecO-like zinc finger	Ankyrin repeat	5	4
FKBP-like	TPR-like	5	3
Immunoglobulin	Protein kinase-like (PK-like)	5	5
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	5	5
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	5	3
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	5	2
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	5	4
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	5	3
Rudiment single hybrid motif	Single hybrid motif	5	3
Voltage-gated potassium channels	Periplasmic binding protein-like II	5	3
RING/U-box	FYVE/PHD zinc finger	5	5
Invertebrate chitin-binding proteins	LDL receptor-like module	5	5
LDL receptor-like module	Growth factor receptor domain	5	5
BEACH domain	WD40 repeat-like	5	5
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	5	4
GroES-like	GroES-like	5	2
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	5	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	5	4
Ankyrin repeat	SH3-domain	4	3
Periplasmic binding protein-like I	Voltage-gated potassium channels	4	2
L27 domain	SH3-domain	4	4
ARM repeat	Clathrin adaptor appendage domain	4	4
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	4	4
POZ domain	Galactose-binding domain-like	4	2
PurM N-terminal domain-like	PurM C-terminal domain-like	4	4
PH domain-like	FYVE/PHD zinc finger	4	4
Chitinase insertion domain	Chitinase insertion domain	4	4
Bromodomain	Bromodomain	4	4
F-box domain	WD40 repeat-like	4	3
Spectrin repeat	EF-hand	4	4
Heme-dependent peroxidases	Heme-dependent peroxidases	4	2
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	4	2
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	4	4
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	4	3
(Trans)glycosidases	(Trans)glycosidases	4	4
Subtilisin-like	Galactose-binding domain-like	4	4
L27 domain	P-loop containing nucleoside triphosphate hydrolases	4	4
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	4	4
Growth factor receptor domain	YWTD domain	4	4
PH domain-like	Ankyrin repeat	4	3
Spectrin repeat	PH domain-like	4	4
RNase III domain-like	dsRNA-binding domain-like	4	4
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	4	3
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	4	4
Spectrin repeat	SH3-domain	4	4
Ubiquitin-like	Protein kinase-like (PK-like)	4	4
EF-hand	RING/U-box	4	4
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	4	2
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	4	1
SRCR-like	SRCR-like	4	4
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	4	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	4	2
Growth factor receptor domain	Complement control module/SCR domain	4	4
alpha/beta-Hydrolases	alpha/beta-Hydrolases	4	1
Cysteine-rich domain	GTPase activation domain, GAP	4	4
Phospholipase D/nuclease	Phospholipase D/nuclease	4	3
ENTH/VHS domain	GAT-like domain	4	2
Ligand-binding domain in the NO signalling and Golgi transport	Nucleotide cyclase	4	3
EF-hand	Cysteine proteinases	4	4
Clc chloride channel	CBS-domain pair	4	2
Folate-binding domain	Aminomethyltransferase beta-barrel domain	4	4
TATA-box binding protein-like	TATA-box binding protein-like	4	2
SAM/Pointed domain	"Winged helix" DNA-binding domain	4	3
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	4	3
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	4	3
UBA-like	RNA-binding domain, RBD	4	2
Periplasmic binding protein-like II	Periplasmic binding protein-like II	4	2
POZ domain	POZ domain	4	4
ARM repeat	PH domain-like	4	4
Cullin repeat-like	"Winged helix" DNA-binding domain	4	1
Cullin repeat-like	Cullin homology domain	4	1
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	4	4
BRCT domain	BRCT domain	4	4
UBA-like	UBA-like	4	4
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	4	3
FAS1 domain	FAS1 domain	4	4
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	4	3
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	4	3
Integrin alpha N-terminal domain	Integrin domains	4	4
PGBD-like	Metalloproteases ("zincins"), catalytic domain	4	2
PGBD-like	Hemopexin-like domain	4	2
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	4	3
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	4	4
FYVE/PHD zinc finger	SET domain	4	4
WW domain	Hect, E3 ligase catalytic domain	4	3
Integrin domains	Integrin domains	4	4
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	4	3
CoA-dependent acyltransferases	CoA-dependent acyltransferases	4	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	4	3
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	4	1
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	4	2
Translation proteins	Ribosomal protein S5 domain 2-like	4	2
GTPase activation domain, GAP	SH2 domain	3	3
Translation proteins	ThrRS/AlaRS common domain	3	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	2
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	3	3
Protease propeptides/inhibitors	Galactose-binding domain-like	3	3
Sec7 domain	PH domain-like	3	3
Ankyrin repeat	POZ domain	3	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	2
Tudor/PWWP/MBT	SAM/Pointed domain	3	3
ClpP/crotonase	ClpP/crotonase	3	2
POZ domain	Galactose oxidase, central domain	3	3
PH domain-like	EF-hand	3	3
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	3	3
FabD/lysophospholipase-like	ACP-like	3	2
Ubiquitin-like	Ras GEF	3	3
Single hybrid motif	CoA-dependent acyltransferases	3	3
Ankyrin repeat	DEATH domain	3	3
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	3	2
Thiolase-like	FabD/lysophospholipase-like	3	2
RING/U-box	UBA-like	3	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	3	3
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	3	1
SH3-domain	GTPase activation domain, GAP	3	3
PriA/YqbF domain	GINS helical bundle-like	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	3	3
RING/U-box	NHL repeat	3	3
Macro domain-like	Zn-dependent exopeptidases	3	1
FAD/NAD(P)-binding domain	Aminomethyltransferase beta-barrel domain	3	3
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	3	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Ubiquitin-like	3	3
(Trans)glycosidases	Galactose-binding domain-like	3	3
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	3	2
SAM/Pointed domain	PDZ domain-like	3	2
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	3	3
FabD/lysophospholipase-like	alpha/beta-Hydrolases	3	2
WW domain	FF domain	3	3
PX domain	Protein kinase-like (PK-like)	3	3
Ribonuclease H-like	DNA/RNA polymerases	3	3
Calponin-homology domain, CH-domain	E set domains	3	3
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
Thyroglobulin type-1 domain	EF-hand	3	3
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
SH2 domain	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
Complement control module/SCR domain	EGF/Laminin	3	3
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	3	1
NAD(P)-binding Rossmann-fold domains	ACP-like	3	2
Calpain large subunit, middle domain (domain III)	EF-hand	3	3
Thiolase-like	ACP-like	3	2
PH domain-like	Oxysterol-binding protein-like	3	2
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	2
Galactose-binding domain-like	Growth factor receptor domain	3	3
PH domain-like	WD40 repeat-like	3	3
L domain-like	Growth factor receptor domain	3	3
ARM repeat	RING/U-box	3	3
B-box zinc-binding domain	NHL repeat	3	2
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	3	1
Growth factor receptor domain	Spermadhesin, CUB domain	3	3
TRAF domain-like	TRAF domain-like	3	3
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	3	2
Ankyrin repeat	Protein kinase-like (PK-like)	3	3
Zinc beta-ribbon	Cyclin-like	3	2
Tudor/PWWP/MBT	HIT/MYND zinc finger-like	3	3
BAR/IMD domain-like	PH domain-like	3	2
Thiolase-like	GroES-like	3	2
Immunoglobulin	TSP-1 type 1 repeat	3	3
PH domain-like	Ras GEF	3	3
Galactose-binding domain-like	Concanavalin A-like lectins/glucanases	3	2
BAR/IMD domain-like	Ankyrin repeat	3	2
ARM repeat	Toll/Interleukin receptor TIR domain	3	1
GroES-like	alpha/beta-Hydrolases	3	2
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	2
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	3	3
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	3	3
Serine protease inhibitors	Serine protease inhibitors	3	2
Hairpin loop containing domain-like	Hairpin loop containing domain-like	3	2
Ankyrin repeat	SAM/Pointed domain	3	3
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	3	2
Calponin-homology domain, CH-domain	EF-hand	3	3
WD40 repeat-like	TPR-like	3	3
SNARE-like	SNARE fusion complex	3	2
GroES-like	ACP-like	3	2
Nucleic acid-binding proteins	Translation proteins SH3-like domain	3	2
ACP-like	alpha/beta-Hydrolases	3	2
SRCR-like	Trypsin-like serine proteases	3	3
LDL receptor-like module	Glycoside hydrolase/deacetylase	3	3
EF-hand	PLC-like phosphodiesterases	3	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	3	3
RNase III domain-like	RNase III domain-like	3	3
WD40 repeat-like	Tricorn protease domain 2	3	3
Hormone receptor domain	Family A G protein-coupled receptor-like	3	3
cAMP-binding domain-like	Protein kinase-like (PK-like)	3	1
LDL receptor-like module	SRCR-like	3	3
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	3	3
Thiolase-like	NAD(P)-binding Rossmann-fold domains	3	2
SAM/Pointed domain	Toll/Interleukin receptor TIR domain	3	1
Leukotriene A4 hydrolase N-terminal domain	Leukotriene A4 hydrolase N-terminal domain	3	1
WD40 repeat-like	Putative isomerase YbhE	3	3
Galactose-binding domain-like	Complement control module/SCR domain	3	3
EF-hand	SH2 domain	3	3
ADC-like	P-loop containing nucleoside triphosphate hydrolases	3	3
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	3	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	3	2
ADC-like	Cdc48 domain 2-like	3	3
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	3	3
EF-hand	SH3-domain	3	3
Ubiquitin-like	RING/U-box	3	3
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	3	3
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	3	2
PH domain-like	PLC-like phosphodiesterases	3	3
Protein kinase-like (PK-like)	PDZ domain-like	3	3
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	3	3
Tudor/PWWP/MBT	FYVE/PHD zinc finger	3	3
RING/U-box	Ankyrin repeat	3	3
PDZ domain-like	Glucocorticoid receptor-like (DNA-binding domain)	3	3
FabD/lysophospholipase-like	GroES-like	3	2
FAD/NAD(P)-binding domain	Folate-binding domain	3	3
Calponin-homology domain, CH-domain	PH domain-like	3	3
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	3	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	3	2
Mib/herc2 domain-like	Ankyrin repeat	3	3
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	3	3
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	3	3
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	3	2
TPR-like	RING/U-box	3	3
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	3	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	3
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	3	2
SMAD MH1 domain	SMAD/FHA domain	3	2
p53-like transcription factors	E set domains	3	3
Thiolase-like	alpha/beta-Hydrolases	3	2
RING/U-box	CCCH zinc finger	3	3
Galactose-binding domain-like	Galactose-binding domain-like	3	3
ENTH/VHS domain	I/LWEQ domain	3	1
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
Protease propeptides/inhibitors	Subtilisin-like	3	3
L domain-like	Protein kinase-like (PK-like)	3	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
NAD(P)-binding Rossmann-fold domains	alpha/beta-Hydrolases	3	2
ARID-like	ARM repeat	3	2
FAD-linked reductases, C-terminal domain	Aminomethyltransferase beta-barrel domain	3	3
GAF domain-like	HD-domain/PDEase-like	3	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	3	2
Flavoproteins	Riboflavin synthase domain-like	3	3
Ubiquitin-like	Thioredoxin-like	3	3
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	3	2
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	3	2
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	3	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	3	3
Sec63 N-terminal domain-like	E set domains	3	2
PH domain-like	BEACH domain	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	2
Complement control module/SCR domain	Concanavalin A-like lectins/glucanases	3	3
FF domain	FF domain	3	3
FAD-linked reductases, C-terminal domain	Folate-binding domain	3	3
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	2	1
NTF2-like	UBA-like	2	2
WW domain	PDZ domain-like	2	2
SH2 domain	(Phosphotyrosine protein) phosphatases II	2	2
Macro domain-like	CRAL/TRIO domain	2	1
SAM/Pointed domain	PH domain-like	2	2
Translational machinery components	L30e-like	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	DBL homology domain (DH-domain)	2	2
N-terminal domain of cbl (N-cbl)	RING/U-box	2	2
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	2	2
SAM/Pointed domain	SH2 domain	2	2
LDL receptor-like module	Concanavalin A-like lectins/glucanases	2	2
Integrin domains	Integrin beta tail domain	2	2
Invertebrate chitin-binding proteins	Trypsin-like serine proteases	2	2
WD40 repeat-like	DPP6 N-terminal domain-like	2	2
ARM repeat	"Winged helix" DNA-binding domain	2	1
CCCH zinc finger	CCCH zinc finger	2	1
RNA-binding domain, RBD	SPOC domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	2	2
Saposin	Metallo-dependent phosphatases	2	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	2	1
Putative DNA-binding domain	SAND domain-like	2	2
PH domain-like	Ypt/Rab-GAP domain of gyp1p	2	1
DPY module	DPY module	2	2
LEM domain	RNA-binding domain, RBD	2	1
post-HMGL domain-like	Single hybrid motif	2	1
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	2	2
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	2	2
Probable ACP-binding domain of malonyl-CoA ACP transacylase	GroES-like	2	1
Rudiment single hybrid motif	ClpP/crotonase	2	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	ACP-like	2	1
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	2	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	2	2
SNARE fusion complex	SNARE fusion complex	2	2
Cysteine-rich domain	Ubiquitin-like	2	2
TPR-like	Clavaminate synthase-like	2	2
L domain-like	Family A G protein-coupled receptor-like	2	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	2
SMAD/FHA domain	Protein kinase-like (PK-like)	2	1
Growth factor receptor domain	Protein kinase-like (PK-like)	2	2
FMN-linked oxidoreductases	alpha-helical ferredoxin	2	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	2	1
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	2	2
Plexin repeat	vWA-like	2	2
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	2	2
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	2	2
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	2
Tropomyosin	Tropomyosin	2	2
PreATP-grasp domain	Aldolase	2	1
PYP-like sensor domain (PAS domain)	HD-domain/PDEase-like	2	1
vWA-like	beta-sandwich domain of Sec23/24	2	2
GST C-terminal domain-like	eEF-1beta-like	2	1
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	2	2
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	2	2
Immunoglobulin	Concanavalin A-like lectins/glucanases	2	2
CRAL/TRIO domain	Spectrin repeat	2	2
RING/U-box	Bromodomain	2	2
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	1
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	2	1
ARM repeat	RNI-like	2	2
cAMP-binding domain-like	Ubiquitin-like	2	2
Translation proteins	Initiation factor IF2/eIF5b, domain 3	2	2
Invertebrate chitin-binding proteins	SRCR-like	2	2
Growth factor receptor domain	Fibronectin type III	2	2
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	2	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	2	2
DPY module	Growth factor receptor domain	2	2
PX domain	BAR/IMD domain-like	2	2
Calponin-homology domain, CH-domain	SH3-domain	2	2
PreATP-grasp domain	post-HMGL domain-like	2	1
Transcription factor STAT-4 N-domain	STAT	2	1
Aldolase	Single hybrid motif	2	1
Family A G protein-coupled receptor-like	Family A G protein-coupled receptor-like	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	2
Formyltransferase	FMT C-terminal domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	E set domains	2	1
SAM/Pointed domain	GTPase activation domain, GAP	2	2
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	2	1
Regulator of G-protein signaling, RGS	PX domain	2	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	2	2
L domain-like	NTF2-like	2	2
PDZ domain-like	RING/U-box	2	2
Immunoglobulin	EGF/Laminin	2	2
HMG-box	HMG-box	2	2
ARM repeat	Cysteine proteinases	2	1
EF-hand	C-terminal domain of PLC-beta	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	2
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	2	2
t-snare proteins	SNARE fusion complex	2	2
MIR domain	IP3 receptor type 1 binding core, domain 2	2	2
Kelch motif	EGF/Laminin	2	2
E set domains	GTPase activation domain, GAP	2	2
Sema domain	Immunoglobulin	2	2
L domain-like	Fibronectin type III	2	2
Plexin repeat	EGF/Laminin	2	2
Regulator of G-protein signaling, RGS	PH domain-like	2	2
Spermadhesin, CUB domain	Kelch motif	2	2
RCC1/BLIP-II	Galactose-binding domain-like	2	2
EF-hand	Mitochondrial carrier	2	2
Transcription factor STAT-4 N-domain	SH2 domain	2	1
NAD(P)-binding Rossmann-fold domains	SCP-like	2	2
Sema domain	E set domains	2	2
vWA-like	Integrin domains	2	2
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	2	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	2	2
"Winged helix" DNA-binding domain	E set domains	2	1
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	2	2
Galactose-binding domain-like	C-type lectin-like	2	2
PH domain-like	Moesin tail domain	2	1
Taf5 N-terminal domain-like	WD40 repeat-like	2	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	2	2
DNA-binding domain	FYVE/PHD zinc finger	2	2
ARID-like	Chromo domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	2	2
Aconitase iron-sulfur domain	LeuD/IlvD-like	2	1
MIT domain	Protein kinase-like (PK-like)	2	2
ARM repeat	Hect, E3 ligase catalytic domain	2	2
Bromodomain	Tudor/PWWP/MBT	2	2
Tudor/PWWP/MBT	ARID-like	2	2
TPR-like	HCP-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
"Winged helix" DNA-binding domain	Ubiquitin-like	2	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	2	1
cAMP-binding domain-like	Ras GEF	2	2
Staphylococcal nuclease	Tudor/PWWP/MBT	2	2
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	2	2
Second domain of FERM	Moesin tail domain	2	1
Rudiment single hybrid motif	post-HMGL domain-like	2	1
Mib/herc2 domain-like	Hect, E3 ligase catalytic domain	2	2
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	2	2
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	2	2
Zn-finger domain of Sec23/24	vWA-like	2	2
Mib/herc2 domain-like	RING/U-box	2	2
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	2	2
STAT	p53-like transcription factors	2	1
vWA-like	Helical domain of Sec23/24	2	2
Transcription factor STAT-4 N-domain	p53-like transcription factors	2	1
C-type lectin-like	C-type lectin-like	2	1
Plexin repeat	E set domains	2	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	2	2
PurM N-terminal domain-like	PurM N-terminal domain-like	2	2
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	2	1
Subtilisin-like	Growth factor receptor domain	2	2
L domain-like	Outer arm dynein light chain 1	2	2
HR1 repeat	HR1 repeat	2	2
B-box zinc-binding domain	TRAF domain-like	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Cysteine-rich domain	2	2
Kringle-like	Protein kinase-like (PK-like)	2	1
GAF domain-like	GAF domain-like	2	1
Integrin domains	EGF/Laminin	2	2
Ypt/Rab-GAP domain of gyp1p	RUN domain-like	2	2
Staphylococcal nuclease	Staphylococcal nuclease	2	2
Aldolase	post-HMGL domain-like	2	1
BRK domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
N-terminal domain of cbl (N-cbl)	EF-hand	2	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	2	2
Class II aaRS and biotin synthetases	Translation proteins	2	1
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	2	2
N-terminal domain of cbl (N-cbl)	SH2 domain	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	PDZ domain-like	2	2
Rudiment single hybrid motif	Aldolase	2	1
CCHHC domain	CCHHC domain	2	2
DBL homology domain (DH-domain)	Ras GEF	2	2
HR1 repeat	Protein kinase-like (PK-like)	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	1
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	2	2
PDZ domain-like	Cysteine-rich domain	2	2
Cysteine-rich DNA binding domain, (DM domain)	UBA-like	2	1
BAR/IMD domain-like	GTPase activation domain, GAP	2	2
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	2	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	2
P-loop containing nucleoside triphosphate hydrolases	Concanavalin A-like lectins/glucanases	2	2
MIR domain	MIR domain	2	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
Restriction endonuclease-like	RuvA domain 2-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	2	2
Spectrin repeat	DBL homology domain (DH-domain)	2	2
Ubiquitin-like	ARM repeat	2	2
Ankyrin repeat	TPR-like	2	2
PurM C-terminal domain-like	PurM C-terminal domain-like	2	2
Frizzled cysteine-rich domain	Trypsin-like serine proteases	2	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	2	1
DUSP-like	Cysteine proteinases	2	2
UBC-like	UBA-like	2	2
Pectin lyase-like	Pectin lyase-like	2	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	2	2
p53-like transcription factors	SH2 domain	2	1
STAT	SH2 domain	2	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	2	2
Chaperone J-domain	Homeodomain-like	2	2
Frizzled cysteine-rich domain	LDL receptor-like module	2	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	2	2
TSP-1 type 1 repeat	BPTI-like	2	2
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	2
P-loop containing nucleoside triphosphate hydrolases	Nucleotidylyl transferase	2	2
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	2	2
FMN-linked oxidoreductases	Nucleotide-binding domain	2	2
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	2	2
SH3-domain	Fibronectin type III	2	2
Probable ACP-binding domain of malonyl-CoA ACP transacylase	alpha/beta-Hydrolases	2	1
Plexin repeat	Integrin domains	2	2
Serpins	Serpins	2	1
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
EF-hand	Riboflavin synthase domain-like	2	2
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	2	1
EGF/Laminin	Integrin beta tail domain	2	2
vWA-like	EGF/Laminin	2	2
vWA-like	Integrin beta tail domain	2	2
ARM repeat	Subdomain of clathrin and coatomer appendage domain	2	2
Ubiquitin-like	Cap-Gly domain	2	2
Ubiquitin-like	Ran binding protein zinc finger-like	2	2
C-type lectin-like	Complement control module/SCR domain	2	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	1
PAH2 domain	PAH2 domain	2	2
RCC1/BLIP-II	RCC1/BLIP-II	2	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	2	2
Cysteine-rich domain	SH2 domain	2	2
ArfGap/RecO-like zinc finger	SH3-domain	2	1
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	2	2
Plexin repeat	Integrin beta tail domain	2	2
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	2	1
Sema domain	GTPase activation domain, GAP	2	2
Single hybrid motif	ClpP/crotonase	2	1
Regulator of G-protein signaling, RGS	Ubiquitin-like	2	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	2	2
Intermediate filament protein, coiled coil region	Intermediate filament protein, coiled coil region	2	2
PH domain-like	C-terminal domain of PLC-beta	2	2
PreATP-grasp domain	ClpP/crotonase	2	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	2	2
SH2 domain	RING/U-box	2	2
Tudor/PWWP/MBT	Chromo domain-like	2	2
Galactose-binding domain-like	Hect, E3 ligase catalytic domain	2	2
WWE domain	RING/U-box	2	2
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	2	2
C-terminal, gelsolin-like domain of Sec23/24	Actin depolymerizing proteins	2	1
RNA-binding domain, RBD	Cyclophilin-like	2	2
L domain-like	UBA-like	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
Plexin repeat	GTPase activation domain, GAP	2	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	2	2
PX domain	Ubiquitin-like	2	2
E set domains	Ankyrin repeat	2	2
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	2	2
Surp module (SWAP domain)	Surp module (SWAP domain)	2	2
Mib/herc2 domain-like	Galactose-binding domain-like	2	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	2	2
Ankyrin repeat	SOCS box-like	2	1
SH2 domain	SOCS box-like	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	2
Calponin-homology domain, CH-domain	GAS2 domain-like	2	2
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	2	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	2
TPR-like	Chaperone J-domain	2	2
Ubiquitin-like	Cysteine proteinases	2	1
Probable ACP-binding domain of malonyl-CoA ACP transacylase	NAD(P)-binding Rossmann-fold domains	2	1
Ubiquitin-like	Moesin tail domain	2	1
EGF/Laminin	TIMP-like	2	2
EF-hand	Rhomboid-like	2	2
SMAD/FHA domain	"Winged helix" DNA-binding domain	2	2
Mib/herc2 domain-like	Mib/herc2 domain-like	2	2
SAM/Pointed domain	Cysteine-rich domain	2	2
Glutathione synthetase ATP-binding domain-like	Aldolase	2	1
vWA-like	SPOC domain-like	2	2
LDL receptor-like module	Complement control module/SCR domain	2	2
E set domains	Cysteine proteinases	2	2
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	2	2
Cysteine proteinases	Ribonuclease H-like	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Ribonuclease H-like	Nucleic acid-binding proteins	1	1
TPR-like	PH domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Protein kinase-like (PK-like)	1	1
SET domain	beta-beta-alpha zinc fingers	1	1
WD40 repeat-like	Cysteine proteinases	1	1
RuvA domain 2-like	Nucleic acid-binding proteins	1	1
RCC1/BLIP-II	Mib/herc2 domain-like	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	1	1
DEATH domain	Toll/Interleukin receptor TIR domain	1	1
L domain-like	WD40 repeat-like	1	1
ISP domain	Bet v1-like	1	1
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	1	1
beta-sandwich domain of Sec23/24	Family A G protein-coupled receptor-like	1	1
FYVE/PHD zinc finger	SMAD/FHA domain	1	1
LDL receptor-like module	Immunoglobulin	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Aldolase	AFP III-like domain	1	1
Methuselah ectodomain	Family A G protein-coupled receptor-like	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
PH domain-like	Immunoglobulin	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
Saposin	Saposin	1	1
HAD-like	BRCT domain	1	1
CRAL/TRIO domain	PH domain-like	1	1
Nitric oxide (NO) synthase oxygenase domain	Flavoproteins	1	1
PMP inhibitors	PMP inhibitors	1	1
R3H domain	RNA-binding domain, RBD	1	1
TPR-like	RNA-binding domain, RBD	1	1
Rap/Ran-GAP	Rap/Ran-GAP	1	1
ACP-like	ALDH-like	1	1
FYVE/PHD zinc finger	Clavaminate synthase-like	1	1
LDL receptor-like module	Galactose-binding domain-like	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
Inhibitor of apoptosis (IAP) repeat	UBC-like	1	1
Retrovirus zinc finger-like domains	RING/U-box	1	1
3-carboxy-cis,cis-mucoante lactonizing enzyme	Kelch motif	1	1
ENTH/VHS domain	RNA-binding domain, RBD	1	1
RNA-binding domain, RBD	NTF2-like	1	1
PDZ domain-like	"Winged helix" DNA-binding domain	1	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
DEATH domain	Protein kinase-like (PK-like)	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
Heme-dependent peroxidases	EF-hand	1	1
PX domain	PH domain-like	1	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	1	1
Notch domain	Ankyrin repeat	1	1
PX domain	MIT domain	1	1
L domain-like	Ubiquitin-like	1	1
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
EF-hand	Isochorismatase-like hydrolases	1	1
Protein kinase-like (PK-like)	Rhodanese/Cell cycle control phosphatase	1	1
EF-hand	GAS2 domain-like	1	1
vWA-like	Immunoglobulin	1	1
Smc hinge domain	Tropomyosin	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
TPR-like	Ran binding protein zinc finger-like	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
WW domain	UBA-like	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Cap-Gly domain	1	1
RING/U-box	PUA domain-like	1	1
RNI-like	Toll/Interleukin receptor TIR domain	1	1
PH domain-like	BSD domain-like	1	1
Formyltransferase	ACP-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Elafin-like	Fibronectin type III	1	1
P-loop containing nucleoside triphosphate hydrolases	Cysteine-rich domain	1	1
R3H domain	Ribonuclease H-like	1	1
Bet v1-like	HAD-like	1	1
TRAF domain-like	NRDP1 C-terminal domain-like	1	1
Nitric oxide (NO) synthase oxygenase domain	Riboflavin synthase domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SET domain	1	1
FnI-like domain	Leech antihemostatic proteins	1	1
Cadherin-like	Growth factor receptor domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	1	1
E set domains	DEATH domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
TRAF domain-like	POZ domain	1	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	1	1
FKBP-like	FKBP-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	1	1
C-type lectin-like	Fibronectin type III	1	1
Second domain of FERM	FAT domain of focal adhesion kinase	1	1
PH domain-like	Phospholipase D/nuclease	1	1
BAR/IMD domain-like	SH2 domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	1	1
Immunoglobulin	Growth factor receptor domain	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
L27 domain	L27 domain	1	1
TAZ domain	TAZ domain	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	1	1
FnI-like domain	Growth factor receptor domain	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
Bromodomain	HIT/MYND zinc finger-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Ubiquitin-like	AN1-like Zinc finger	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	1	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	1	1
Immunoglobulin	SH3-domain	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Concanavalin A-like lectins/glucanases	BEACH domain	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
Calponin-homology domain, CH-domain	SH2 domain	1	1
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Tex N-terminal region-like	Ribonuclease H-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
EGF/Laminin	NHL repeat	1	1
RAP domain-like	RAP domain-like	1	1
HIT-like	HIT-like	1	1
Single hybrid motif	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
SMAD/FHA domain	Cap-Gly domain	1	1
Growth factor receptor domain	Notch domain	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
Protein kinase-like (PK-like)	L27 domain	1	1
Cytochrome b5-like heme/steroid binding domain	Oxidoreductase molybdopterin-binding domain	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
SAP domain	RNA-binding domain, RBD	1	1
PH domain-like	Ran binding protein zinc finger-like	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
Cyclin-like	HAD-like	1	1
SH3-domain	SAM/Pointed domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Class I glutamine amidotransferase-like	Composite domain of metallo-dependent hydrolases	1	1
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	1	1
PH domain-like	"Winged helix" DNA-binding domain	1	1
FnI-like domain	Fibronectin type III	1	1
Cytochrome b5-like heme/steroid binding domain	Tudor/PWWP/MBT	1	1
L domain-like	Calponin-homology domain, CH-domain	1	1
Cystatin/monellin	Cysteine proteinases	1	1
BRCT domain	WGR domain-like	1	1
beta-beta-alpha zinc fingers	WW domain	1	1
SMAD/FHA domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
UBA-like	CCCH zinc finger	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
RNI-like	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
L domain-like	FnI-like domain	1	1
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	1	1
Cytochrome b5-like heme/steroid binding domain	Mib/herc2 domain-like	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
BRCT domain	DBL homology domain (DH-domain)	1	1
FYVE/PHD zinc finger	SAP domain	1	1
L domain-like	Heme-dependent peroxidases	1	1
P-loop containing nucleoside triphosphate hydrolases	FF domain	1	1
Chaperone J-domain	ARM repeat	1	1
ARID-like	Clavaminate synthase-like	1	1
SH3-domain	ARM repeat	1	1
GTPase activation domain, GAP	ARM repeat	1	1
Glutaminase/Asparaginase	Ankyrin repeat	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
Tricorn protease domain 2	Nucleoporin domain	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Cadherin-like	Protein kinase-like (PK-like)	1	1
CRAL/TRIO N-terminal domain	PapD-like	1	1
Homeodomain-like	FAD/NAD(P)-binding domain	1	1
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	1	1
TGS-like	Class II aaRS ABD-related	1	1
RNA-binding domain, RBD	L domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
SAM/Pointed domain	Bet v1-like	1	1
Growth factor receptor domain	Thyroglobulin type-1 domain	1	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	1	1
Clavaminate synthase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Actin depolymerizing proteins	SH3-domain	1	1
PH domain-like	HMG-box	1	1
Plexin repeat	Plexin repeat	1	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	1	1
Tudor/PWWP/MBT	NAD(P)-binding Rossmann-fold domains	1	1
GFP-like	YWTD domain	1	1
C-type lectin-like	Immunoglobulin	1	1
USP8 N-terminal domain-like	Cysteine proteinases	1	1
G protein-binding domain	Cysteine-rich domain	1	1
CBS-domain pair	CBS-domain pair	1	1
E set domains	(Trans)glycosidases	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
Trypsin-like serine proteases	PDZ domain-like	1	1
CalX-like	CalX-like	1	1
TPR-like	ARM repeat	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Protein kinase-like (PK-like)	RCC1/BLIP-II	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
RILP dimerisation region	WD40 repeat-like	1	1
EGF/Laminin	Galactose-binding domain-like	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
SAP domain	Concanavalin A-like lectins/glucanases	1	1
EF-hand	DUSP-like	1	1
WWE domain	WWE domain	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
A DNA-binding domain in eukaryotic transcription factors	Leucine zipper domain	1	1
Rap/Ran-GAP	POZ domain	1	1
TPR-like	"Winged helix" DNA-binding domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Composite domain of metallo-dependent hydrolases	1	1
DNA-binding domain	Bromodomain	1	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	1	1
Histone-fold	POZ domain	1	1
EF-hand	Glycoside hydrolase/deacetylase	1	1
Kelch motif	Growth factor receptor domain	1	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	1	1
TPR-like	PUA domain-like	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
(Phosphotyrosine protein) phosphatases II	Chaperone J-domain	1	1
CAD & PB1 domains	PDZ domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
HCP-like	HCP-like	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
SH2 domain	Ubiquitin-like	1	1
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	1	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	1	1
HIT/MYND zinc finger-like	HIT/MYND zinc finger-like	1	1
Concanavalin A-like lectins/glucanases	FnI-like domain	1	1
CBS-domain pair	cAMP-binding domain-like	1	1
DEATH domain	Caspase-like	1	1
WD40 repeat-like	EF-hand	1	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Putative DNA-binding domain	Cation efflux protein transmembrane domain-like	1	1
Oxidoreductase molybdopterin-binding domain	E set domains	1	1
SH3-domain	PX domain	1	1
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
cAMP-binding domain-like	PDZ domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	1	1
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	1	1
Ankyrin repeat	Voltage-gated potassium channels	1	1
Cytochrome b5-like heme/steroid binding domain	Galactose-binding domain-like	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
E set domains	Transglutaminase, two C-terminal domains	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	1	1
P-loop containing nucleoside triphosphate hydrolases	Tricorn protease domain 2	1	1
A heparin-binding domain	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
Concanavalin A-like lectins/glucanases	Somatomedin B domain	1	1
Tudor/PWWP/MBT	Galactose-binding domain-like	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
Ribonuclease H-like	SH2 domain	1	1
Hook domain	Troponin coil-coiled subunits	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	1	1
FYVE/PHD zinc finger	Rabenosyn-5 Rab-binding domain-like	1	1
RNA-binding domain, RBD	PWI domain	1	1
N-terminal domain of cbl (N-cbl)	UBA-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	FYVE/PHD zinc finger	1	1
Immunoglobulin	Complement control module/SCR domain	1	1
beta-beta-alpha zinc fingers	Homeodomain-like	1	1
BPTI-like	Concanavalin A-like lectins/glucanases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Chaperone J-domain	1	1
WW domain	FKBP-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	P-loop containing nucleoside triphosphate hydrolases	1	1
ARM repeat	Rap/Ran-GAP	1	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	1	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	1	1
L domain-like	EGF/Laminin	1	1
SAM/Pointed domain	Ras GEF	1	1
EPT/RTPC-like	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	1	1
WW domain	NAD(P)-binding Rossmann-fold domains	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
PH domain-like	Cullin repeat-like	1	1
PH domain-like	NAD kinase/diacylglycerol kinase-like	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
Ankyrin repeat	ADP-ribosylation	1	1
SRCR-like	C-type lectin-like	1	1
HBS1-like domain	Translation proteins	1	1
DBL homology domain (DH-domain)	Quinoprotein alcohol dehydrogenase-like	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
Pseudouridine synthase	PUA domain-like	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
SH2 domain	VPS9 domain	1	1
Nucleotide cyclase	Calcium ATPase, transmembrane domain M	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
Spermadhesin, CUB domain	Complement control module/SCR domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
ARM repeat	alpha/beta knot	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
GST C-terminal domain-like	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
P-loop containing nucleoside triphosphate hydrolases	Rad50 coiled-coil Zn hook	1	1
"Winged helix" DNA-binding domain	Class II aaRS and biotin synthetases	1	1
MIR domain	Concanavalin A-like lectins/glucanases	1	1
DPP6 N-terminal domain-like	TPR-like	1	1
POZ domain	FYVE/PHD zinc finger	1	1
Second domain of FERM	A middle domain of Talin 1	1	1
Galactose-binding domain-like	Fibronectin type III	1	1
P-loop containing nucleoside triphosphate hydrolases	Cystine-knot cytokines	1	1
Second domain of FERM	DBL homology domain (DH-domain)	1	1
Plakin repeat	GAS2 domain-like	1	1
Hect, E3 ligase catalytic domain	Hect, E3 ligase catalytic domain	1	1
E set domains	AMPKBI-like	1	1
WW domain	EF-hand	1	1
CCCH zinc finger	RNA-binding domain, RBD	1	1
MIT domain	MIT domain	1	1
Spermadhesin, CUB domain	Galactose-binding domain-like	1	1
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	1	1
Ribonuclease H-like	RNA-binding domain, RBD	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
Plakin repeat	Plakin repeat	1	1
Trypsin-like serine proteases	Concanavalin A-like lectins/glucanases	1	1
A middle domain of Talin 1	I/LWEQ domain	1	1
P-loop containing nucleoside triphosphate hydrolases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
Rubredoxin-like	RNI-like	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
Creatinase/prolidase N-terminal domain	Creatinase/prolidase N-terminal domain	1	1
CRAL/TRIO domain	CRAL/TRIO domain	1	1
PDZ domain-like	PX domain	1	1
Ubiquitin-like	FAT domain of focal adhesion kinase	1	1
SRCR-like	Pectin lyase-like	1	1
Cadherin-like	Family A G protein-coupled receptor-like	1	1
Phenylalanine zipper	SH2 domain	1	1
FYVE/PHD zinc finger	PDZ domain-like	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
RING/U-box	SH3-domain	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	1	1
NAD kinase/diacylglycerol kinase-like	SAM/Pointed domain	1	1
Calponin-homology domain, CH-domain	Plakin repeat	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	1	1
L domain-like	PDZ domain-like	1	1
MAST3 pre-PK domain-like	PDZ domain-like	1	1
TSP type-3 repeat	TSP type-3 repeat	1	1
WW domain	RING/U-box	1	1
Chaperone J-domain	CSL zinc finger	1	1
Protein kinase-like (PK-like)	KA1-like	1	1
Cysteine proteinases	UBA-like	1	1
ENTH/VHS domain	SH3-domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VHP, Villin headpiece domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	G protein-binding domain	1	1
Phenylalanine zipper	PH domain-like	1	1
L domain-like	PP2C-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SOCS box-like	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
BPTI-like	BPTI-like	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
FF domain	GTPase activation domain, GAP	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
PDZ domain-like	GTPase activation domain, GAP	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
PH domain-like	Quinoprotein alcohol dehydrogenase-like	1	1
Concanavalin A-like lectins/glucanases	ARM repeat	1	1
CRAL/TRIO domain	SH3-domain	1	1
DUSP-like	DUSP-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
ARM repeat	Mib/herc2 domain-like	1	1
Histone-fold	ARM repeat	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	1	1
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	1	1
PurM N-terminal domain-like	Formyltransferase	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
RCC1/BLIP-II	PABC (PABP) domain	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Cation efflux protein transmembrane domain-like	Cation efflux protein transmembrane domain-like	1	1
Tricorn protease domain 2	SNARE fusion complex	1	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
SET domain	WW domain	1	1
TSP type-3 repeat	Concanavalin A-like lectins/glucanases	1	1
PH domain-like	RING/U-box	1	1
Ankyrin repeat	Galactose-binding domain-like	1	1
HMA, heavy metal-associated domain	HAD-like	1	1
FAD/NAD(P)-binding domain	EF-hand	1	1
PUG domain-like	Galactose-binding domain-like	1	1
PH domain-like	Bet v1-like	1	1
RNA-binding domain, RBD	SET domain	1	1
UBA-like	SH3-domain	1	1
Cu,Zn superoxide dismutase-like	Cu,Zn superoxide dismutase-like	1	1
Glutathione synthetase ATP-binding domain-like	Formyltransferase	1	1
Kazal-type serine protease inhibitors	Thyroglobulin type-1 domain	1	1
Chaperone J-domain	RNA-binding domain, RBD	1	1
RUN domain-like	RUN domain-like	1	1
Ankyrin repeat	Hect, E3 ligase catalytic domain	1	1
Ankyrin repeat	WD40 repeat-like	1	1
beta-beta-alpha zinc fingers	FYVE/PHD zinc finger	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
PRP4-like	WD40 repeat-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Tudor/PWWP/MBT	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	1	1
Thioredoxin-like	NHL repeat	1	1
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Leech antihemostatic proteins	Leech antihemostatic proteins	1	1
HSP20-like chaperones	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
PK beta-barrel domain-like	PK C-terminal domain-like	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
P-loop containing nucleoside triphosphate hydrolases	TPR-like	1	1
Ribonuclease H-like	Ribonuclease H-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
SET domain	Bromodomain	1	1
Ankyrin repeat	Fibronectin type III	1	1
vWA-like	Sensory domain-like	1	1
VPS9 domain	Ubiquitin-like	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
PDZ domain-like	Ras GEF	1	1
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	1	1
Cysteine proteinases	Transglutaminase, two C-terminal domains	1	1
Cap-Gly domain	Cap-Gly domain	1	1
GFP-like	Growth factor receptor domain	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Eukaryotic type KH-domain (KH-domain type I)	SAM/Pointed domain	1	1
EGF/Laminin	Notch domain	1	1
Cysteine-rich domain	DBL homology domain (DH-domain)	1	1
CRAL/TRIO domain	DBL homology domain (DH-domain)	1	1
B-box zinc-binding domain	FYVE/PHD zinc finger	1	1
TAZ domain	Bromodomain	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Immunoglobulin	Heme-dependent peroxidases	1	1
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
E set domains	Complement control module/SCR domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
ARM repeat	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain	1	1
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
WD40 repeat-like	SNARE fusion complex	1	1
IP3 receptor type 1 binding core, domain 2	IP3 receptor type 1 binding core, domain 2	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Cytochrome b5-like heme/steroid binding domain	HSP20-like chaperones	1	1
TPR-like	Metallo-dependent phosphatases	1	1
Ubiquitin-like	DBL homology domain (DH-domain)	1	1
PR-1-like	PR-1-like	1	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	1	1
Regulator of G-protein signaling, RGS	Cysteine-rich domain	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
Carbon-nitrogen hydrolase	HIT-like	1	1
Mss4-like	P-loop containing nucleoside triphosphate hydrolases	1	1
L30e-like	alpha/beta knot	1	1
SH2 domain	UBA-like	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
Doublecortin (DC)	Protein kinase-like (PK-like)	1	1
FMT C-terminal domain-like	ACP-like	1	1
Spectrin repeat	WW domain	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	1	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
GTPase activation domain, GAP	CRAL/TRIO domain	1	1
CRAL/TRIO domain	ARM repeat	1	1
vWA-like	C-terminal domain of Ku80	1	1
PAH2 domain	Homeodomain-like	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
F-box domain	Concanavalin A-like lectins/glucanases	1	1
dsRNA-binding domain-like	Tudor/PWWP/MBT	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
EGF/Laminin	Ankyrin repeat	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
SAP domain	P-loop containing nucleoside triphosphate hydrolases	1	1
ARM repeat	WWE domain	1	1
SH2 domain	PLC-like phosphodiesterases	1	1
BAR/IMD domain-like	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	1	1
FYVE/PHD zinc finger	Concanavalin A-like lectins/glucanases	1	1
YjgF-like	YjgF-like	1	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	1	1
PH domain-like	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	1	1
GST C-terminal domain-like	Methionyl-tRNA synthetase (MetRS), Zn-domain	1	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	1	1
Chaperone J-domain	Thioredoxin-like	1	1
Myosin rod fragments	Tropomyosin	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Cap-Gly domain	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
Kelch motif	Fibronectin type III	1	1
Outer arm dynein light chain 1	RNI-like	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
GST C-terminal domain-like	S15/NS1 RNA-binding domain	1	1
Bromodomain	Nuclear receptor coactivator interlocking domain	1	1
Ribonuclease H-like	RuvA domain 2-like	1	1
F-box domain	L domain-like	1	1
SH2 domain	Ras GEF	1	1
RCC1/BLIP-II	Cytochrome b5-like heme/steroid binding domain	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
Kix domain of CBP (creb binding protein)	Nuclear receptor coactivator interlocking domain	1	1
UBC-like	P-loop containing nucleoside triphosphate hydrolases	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Ubiquitin-like	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
BAR/IMD domain-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	1	1
PX domain	Phospholipase D/nuclease	1	1
Galactose-binding domain-like	Kelch motif	1	1
Ankyrin repeat	FabD/lysophospholipase-like	1	1
PUA domain-like	PUA domain-like	1	1
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	1	1
Transglutaminase, two C-terminal domains	Transglutaminase, two C-terminal domains	1	1
Ypt/Rab-GAP domain of gyp1p	SH3-domain	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Concanavalin A-like lectins/glucanases	EF-hand	1	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
BSD domain-like	BSD domain-like	1	1
Galactose-binding domain-like	SAM/Pointed domain	1	1
USP8 N-terminal domain-like	Rhodanese/Cell cycle control phosphatase	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Galactose-binding domain-like	RING/U-box	1	1
YWTD domain	Protein kinase-like (PK-like)	1	1
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	1	1
PABC (PABP) domain	Hect, E3 ligase catalytic domain	1	1
SEA domain	Trypsin-like serine proteases	1	1
Tricorn protease domain 2	Quinoprotein alcohol dehydrogenase-like	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
TPR-like	Fic-like	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
B-box zinc-binding domain	Cyclophilin-like	1	1
POZ domain	Pentapeptide repeat-like	1	1
A heparin-binding domain	Amyloid beta a4 protein copper binding domain (domain 2)	1	1
PurS-like	PurM C-terminal domain-like	1	1
POZ domain	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Cytochrome b5-like heme/steroid binding domain	Hect, E3 ligase catalytic domain	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
F-box domain	Kelch motif	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
PP2C-like	Protein serine/threonine phosphatase 2C, C-terminal domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	PX domain	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
Clavaminate synthase-like	RNI-like	1	1
L domain-like	RING/U-box	1	1
EGF/Laminin	Family A G protein-coupled receptor-like	1	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	1	1
PH domain-like	A middle domain of Talin 1	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
ARID-like	FYVE/PHD zinc finger	1	1
PH domain-like	FAT domain of focal adhesion kinase	1	1
RNA-binding domain, RBD	Tricorn protease domain 2	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Voltage-gated potassium channels	Small-conductance potassium channel	1	1
Concanavalin A-like lectins/glucanases	IP3 receptor type 1 binding core, domain 2	1	1
L domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
Ankyrin repeat	FYVE/PHD zinc finger	1	1
ARM repeat	Galactose-binding domain-like	1	1
Bet v1-like	Bet v1-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
EF-hand	Tropomyosin	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
Nucleotidylyl transferase	Nucleotidylyl transferase	1	1
Second domain of FERM	I/LWEQ domain	1	1
RuvA domain 2-like	SH2 domain	1	1
Tudor/PWWP/MBT	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
Protein kinase-like (PK-like)	SAM/Pointed domain	1	1
CCCH zinc finger	P-loop containing nucleoside triphosphate hydrolases	1	1
UBA-like	Phosphoglycerate mutase-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	1	1
Protease propeptides/inhibitors	Growth factor receptor domain	1	1
ISP transmembrane anchor	ISP domain	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
AN1-like Zinc finger	AN1-like Zinc finger	1	1
EF-hand	Cysteine-rich domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	DNA-binding domain	1	1
PLP-dependent transferases	PK beta-barrel domain-like	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
LDL receptor-like module	Terpenoid cyclases/Protein prenyltransferases	1	1
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	1	1
PDZ domain-like	Regulator of G-protein signaling, RGS	1	1
UBA-like	Ricin B-like lectins	1	1
Hedgehog/DD-peptidase	Hedgehog/intein (Hint) domain	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
Sec7 domain	ARM repeat	1	1
RCC1/BLIP-II	Concanavalin A-like lectins/glucanases	1	1
beta-beta-alpha zinc fingers	Tudor/PWWP/MBT	1	1
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Cyclophilin-like	TPR-like	1	1
PUG domain-like	Cysteine proteinases	1	1
FYVE/PHD zinc finger	Elongation factor TFIIS domain 2	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Phosphofructokinase	Phosphofructokinase	1	1
Ankyrin repeat	LEM domain	1	1
NAD kinase/diacylglycerol kinase-like	NAD kinase/diacylglycerol kinase-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Putative DNA-binding domain	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
UBC-like	RING/U-box	1	1
BRCT domain	Homeodomain-like	1	1
SEA domain	LDL receptor-like module	1	1
WD40 repeat-like	Bromodomain	1	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
WGR domain-like	ADP-ribosylation	1	1
Heme-dependent peroxidases	Riboflavin synthase domain-like	1	1
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	1	1
Concanavalin A-like lectins/glucanases	Family A G protein-coupled receptor-like	1	1
Protein kinase-like (PK-like)	Polo-box domain	1	1
Concanavalin A-like lectins/glucanases	PH domain-like	1	1
TAZ domain	Kix domain of CBP (creb binding protein)	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
BRCT domain	ADP-ribosylation	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
PKD domain	PKD domain	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
Thiolase-like	SCP-like	1	1
Chromo domain-like	BRK domain-like	1	1
WD40 repeat-like	UBC-like	1	1
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	LDL receptor-like module	1	1
SH3-domain	PLC-like phosphodiesterases	1	1
SET domain	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
Histone-fold	PH domain-like	1	1
SMAD/FHA domain	PH domain-like	1	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	1	1
Cystatin/monellin	Cystatin/monellin	1	1
PUA domain-like	eIF1-like	1	1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	1	1
mRNA decapping enzyme DcpS N-terminal domain	HIT-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	1	1
RCC1/BLIP-II	POZ domain	1	1
RING/U-box	Nuclear receptor coactivator interlocking domain	1	1
FKBP-like	EF-hand	1	1
PreATP-grasp domain	Metallo-dependent hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	1	1
DNA clamp	DNA clamp	1	1
SH3-domain	Phosphoglycerate mutase-like	1	1
B-box zinc-binding domain	Bromodomain	1	1
Cna protein B-type domain	Starch-binding domain-like	1	1
POZ domain	WD40 repeat-like	1	1
Metallo-dependent phosphatases	EF-hand	1	1
RuvA domain 2-like	RuvA domain 2-like	1	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	1	1
Nucleotidylyl transferase	tRNA-binding arm	1	1
Plexin repeat	TSP-1 type 1 repeat	1	1
L domain-like	Concanavalin A-like lectins/glucanases	1	1
PX domain	Outer arm dynein light chain 1	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
I/LWEQ domain	I/LWEQ domain	1	1
cAMP-binding domain-like	FabD/lysophospholipase-like	1	1
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	1	1
PUG domain-like	Ubiquitin-like	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
FMN-linked oxidoreductases	dsRNA-binding domain-like	1	1
WWE domain	Hect, E3 ligase catalytic domain	1	1
Chaperone J-domain	E set domains	1	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	1	1
RUN domain-like	PX domain	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Tudor/PWWP/MBT	DNA-binding domain	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
Trypsin-like serine proteases	Immunoglobulin	1	1
Second domain of FERM	RING/U-box	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	1	1
Doublecortin (DC)	Doublecortin (DC)	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	YWTD domain	1	1
HSP20-like chaperones	TPR-like	1	1
SWIB/MDM2 domain	eIF1-like	1	1
Single hybrid motif	HAD-like	1	1
PLC-like phosphodiesterases	Ubiquitin-like	1	1
PUG domain-like	Ran binding protein zinc finger-like	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
Spectrin repeat	GAS2 domain-like	1	1
Arginase/deacetylase	RING/U-box	1	1
Concanavalin A-like lectins/glucanases	SOCS box-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
beta-sandwich domain of Sec23/24	Homeodomain-like	1	1
Regulator of G-protein signaling, RGS	DBL homology domain (DH-domain)	1	1
"Winged helix" DNA-binding domain	Ras GEF	1	1
Cytochrome P450	Cytochrome P450	1	1
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	1	1
TSP-1 type 1 repeat	DEATH domain	1	1
Notch domain	Notch domain	1	1
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	1	1
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
Thyroglobulin type-1 domain	BPTI-like	1	1
Histone-fold	DBL homology domain (DH-domain)	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Ubiquitin-like	HAD-like	1	1
GTPase activation domain, GAP	Bet v1-like	1	1
FYVE/PHD zinc finger	BRK domain-like	1	1
Protein kinase-like (PK-like)	Chaperone J-domain	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	1	1
Heme-dependent peroxidases	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	1	1
TPR-like	RNI-like	1	1
Seven-hairpin glycosidases	PA domain	1	1
Cystine-knot cytokines	Cystine-knot cytokines	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
PreATP-grasp domain	Formyltransferase	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Tex N-terminal region-like	SH2 domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Formyltransferase	ALDH-like	1	1
WD40 repeat-like	FYVE/PHD zinc finger	1	1
Tudor/PWWP/MBT	SET domain	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
TAZ domain	RING/U-box	1	1
Spectrin repeat	Immunoglobulin	1	1
Amyloid beta a4 protein copper binding domain (domain 2)	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
DEK C-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	1	1
Nucleotidylyl transferase	Ribosomal protein L25-like	1	1
Glutathione synthetase ATP-binding domain-like	Composite domain of metallo-dependent hydrolases	1	1
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	1	1
Chromo domain-like	SET domain	1	1
PAZ domain	RNase III domain-like	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Complement control module/SCR domain	Trypsin-like serine proteases	1	1
Pre-PUA domain	PUA domain-like	1	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	1	1
Heme-dependent peroxidases	FnI-like domain	1	1
Nitric oxide (NO) synthase oxygenase domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
PurS-like	PurM N-terminal domain-like	1	1
Ankyrin repeat	PDZ domain-like	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
RNI-like	Ubiquitin-like	1	1
Spectrin repeat	RING/U-box	1	1
Clavaminate synthase-like	Rubredoxin-like	1	1
SAND domain-like	HIT/MYND zinc finger-like	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	1	1
ClpS-like	"Winged helix" DNA-binding domain	1	1
Leech antihemostatic proteins	BPTI-like	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	1	1
RCC1/BLIP-II	Tudor/PWWP/MBT	1	1
FnI-like domain	Cupredoxins	1	1
P-loop containing nucleoside triphosphate hydrolases	Tudor/PWWP/MBT	1	1
P-loop containing nucleoside triphosphate hydrolases	PX domain	1	1
Cytochrome b5-like heme/steroid binding domain	E set domains	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
Growth factor receptor domain	Ankyrin repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	POZ domain	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	1	1
Chromo domain-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
GST C-terminal domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
Ankyrin repeat	L domain-like	1	1
Class I glutamine amidotransferase-like	PreATP-grasp domain	1	1
Galactose-binding domain-like	BRCT domain	1	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	1	1
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	1	1
ARM repeat	BEACH domain	1	1
Rudiment single hybrid motif	Formyltransferase	1	1
BRCT domain	DNA/RNA polymerases	1	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
PA domain	RING/U-box	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
Ran binding protein zinc finger-like	RING/U-box	1	1
SMAD/FHA domain	PDZ domain-like	1	1
TAFH domain-like	Histone-fold	1	1
cAMP-binding domain-like	"Winged helix" DNA-binding domain	1	1
Spectrin repeat	Plakin repeat	1	1
Ankyrin repeat	HIT/MYND zinc finger-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
Composite domain of metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
Cysteine-rich domain	Multiheme cytochromes	1	1
BRK domain-like	Elongation factor TFIIS domain 2	1	1
SH2 domain	Ankyrin repeat	1	1
Immunoglobulin	DEATH domain	1	1
WD40 repeat-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
RNA-binding domain, RBD	Class II aaRS ABD-related	1	1
DBL homology domain (DH-domain)	SH2 domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	1	1
SET domain	Growth factor receptor domain	1	1
YccV-like	ApaG-like	1	1
HR1 repeat	PDZ domain-like	1	1
RING/U-box	NRDP1 C-terminal domain-like	1	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
SH3-domain	RUN domain-like	1	1
RING/U-box	Cyclophilin-like	1	1
EF-hand	Mannose 6-phosphate receptor domain	1	1
Chromo domain-like	Translation proteins	1	1
DBL homology domain (DH-domain)	GTPase activation domain, GAP	1	1
Fibronectin type III	SAM/Pointed domain	1	1
PurM C-terminal domain-like	Formyltransferase	1	1
Kazal-type serine protease inhibitors	EF-hand	1	1
UBA-like	XPC-binding domain	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Pseudouridine synthase	(Phosphotyrosine protein) phosphatases II	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
LDL receptor-like module	Alpha-macroglobulin receptor domain	1	1
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	1	1
IP3 receptor type 1 binding core, domain 2	EF-hand	1	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	1	1
PR-1-like	Crisp domain-like	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
PDZ domain-like	Myosin rod fragments	1	1
Spermadhesin, CUB domain	Concanavalin A-like lectins/glucanases	1	1
FnI-like domain	EGF/Laminin	1	1
Histone-fold	Ras GEF	1	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	1	1
RNA-binding domain, RBD	PABC (PABP) domain	1	1
Translation proteins	Translation proteins	1	1
Second domain of FERM	Protein kinase-like (PK-like)	1	1
Second domain of FERM	PDZ domain-like	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
TRAF domain-like	Cysteine proteinases	1	1
Elafin-like	Immunoglobulin	1	1
G protein-binding domain	PH domain-like	1	1
Galactose mutarotase-like	Glycosyl hydrolase domain	1	1
Plakin repeat	EF-hand	1	1
LDL receptor-like module	L domain-like	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
tRNA-binding arm	Class II aaRS and biotin synthetases	1	1
PP2C-like	PP2C-like	1	1
SEA domain	Frizzled cysteine-rich domain	1	1
vWA-like	Cysteine-rich domain	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Rap/Ran-GAP	PDZ domain-like	1	1
Ankyrin repeat	SET domain	1	1
beta-beta-alpha zinc fingers	"Winged helix" DNA-binding domain	1	1
MIT domain	Cysteine proteinases	1	1
EF-hand	NAD kinase/diacylglycerol kinase-like	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
Immunoglobulin	FnI-like domain	1	1
Galactose-binding domain-like	Protein kinase-like (PK-like)	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	1	1
F-box domain	UBC-like	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
Tubulin nucleotide-binding domain-like	Tubulin nucleotide-binding domain-like	1	1
Methylglyoxal synthase-like	Metallo-dependent hydrolases	1	1
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	1	1
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
CAD & PB1 domains	His-Me finger endonucleases	1	1
PDZ domain-like	BAR/IMD domain-like	1	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	1	1
RING/U-box	Homeodomain-like	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
WD40 repeat-like	Inhibitor of apoptosis (IAP) repeat	1	1
Ubiquitin-like	XPC-binding domain	1	1
BAR/IMD domain-like	Cysteine-rich domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
PX domain	PX domain	1	1
Fibronectin type III	Concanavalin A-like lectins/glucanases	1	1
p53-like transcription factors	DEATH domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
I/LWEQ domain	alpha-catenin/vinculin-like	1	1
DBL homology domain (DH-domain)	Immunoglobulin	1	1
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	1	1
SAP domain	SAP domain	1	1
MgtE membrane domain-like	MgtE membrane domain-like	1	1
Doublecortin (DC)	Quinoprotein alcohol dehydrogenase-like	1	1
Ribonuclease H-like	HRDC-like	1	1
Ankyrin repeat	RNI-like	1	1
ARM repeat	PX domain	1	1
PH domain-like	I/LWEQ domain	1	1
POZ domain	Skp1 dimerisation domain-like	1	1
Histone-fold	Ankyrin repeat	1	1
L domain-like	Actin depolymerizing proteins	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
EF-hand	UBA-like	1	1
SAP domain	RING/U-box	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Eferin C-derminal domain-like	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
RING/U-box	RNA-binding domain, RBD	1	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	1	1
E set domains	Glycosyl hydrolase domain	1	1
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
CCCH zinc finger	UBC-like	1	1
FMT C-terminal domain-like	ALDH-like	1	1
HSP20-like chaperones	Riboflavin synthase domain-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
Cap-Gly domain	Cysteine proteinases	1	1
beta-beta-alpha zinc fingers	Bromodomain	1	1
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	1	1
PRTase-like	PRTase-like	1	1
DNA-binding domain	SET domain	1	1
DNase I-like	RNA-binding domain, RBD	1	1
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
SET domain	Translation proteins	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
CRAL/TRIO domain	PapD-like	1	1
Mib/herc2 domain-like	Tudor/PWWP/MBT	1	1
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	1	1
Kix domain of CBP (creb binding protein)	RING/U-box	1	1
RING/U-box	R3H domain	1	1
Cap-Gly domain	L domain-like	1	1
Tropomyosin	SAM/Pointed domain	1	1
Lysozyme-like	Lysozyme-like	1	1
Thyroglobulin type-1 domain	Leech antihemostatic proteins	1	1
DNase I-like	GTPase activation domain, GAP	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
SAICAR synthase-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
HCP-like	Protein kinase-like (PK-like)	1	1
Ubiquitin-like	SMAD/FHA domain	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Polo-box domain	Polo-box domain	1	1
ARM repeat	Ankyrin repeat	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Pectin lyase-like	C-type lectin-like	1	1
Carbamate kinase-like	ALDH-like	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
Metallo-dependent phosphatases	HIT-like	1	1
TAZ domain	Nuclear receptor coactivator interlocking domain	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Composite domain of metallo-dependent hydrolases	1	1
F-box domain	Pectin lyase-like	1	1
"Winged helix" DNA-binding domain	occludin/ELL-like	1	1
PH domain-like	Fibronectin type III	1	1
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	1	1
PreATP-grasp domain	PreATP-grasp domain	1	1
beta-sandwich domain of Sec23/24	"Winged helix" DNA-binding domain	1	1
DBL homology domain (DH-domain)	Protein kinase-like (PK-like)	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
WD40 repeat-like	Tubby C-terminal domain-like	1	1
SMAD/FHA domain	PX domain	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Tudor/PWWP/MBT	Hect, E3 ligase catalytic domain	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	1	1
Sema domain	TSP-1 type 1 repeat	1	1
Nucleic acid-binding proteins	Prokaryotic type KH domain (KH-domain type II)	1	1
Methylglyoxal synthase-like	Composite domain of metallo-dependent hydrolases	1	1
Complement control module/SCR domain	Somatomedin B domain	1	1
HBS1-like domain	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
PreATP-grasp domain	Composite domain of metallo-dependent hydrolases	1	1
RCC1/BLIP-II	RING/U-box	1	1
Growth factor receptor domain	TSP type-3 repeat	1	1
E set domains	Hect, E3 ligase catalytic domain	1	1
MIR domain	EF-hand	1	1
Dcp2 domain-like	Nudix	1	1
BRK domain-like	Bromodomain	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Kix domain of CBP (creb binding protein)	Bromodomain	1	1
TROVE domain-like	vWA-like	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
SAM/Pointed domain	ADP-ribosylation	1	1
DBL homology domain (DH-domain)	Fibronectin type III	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
SMAD/FHA domain	BRCT domain	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	1	1
Arginase/deacetylase	Arginase/deacetylase	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
PUA domain-like	Ribosomal protein S5 domain 2-like	1	1
p53-like transcription factors	Ankyrin repeat	1	1
Bromodomain	HMG-box	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
PAZ domain	dsRNA-binding domain-like	1	1
ARM repeat	Thioesterase/thiol ester dehydrase-isomerase	1	1
YWTD domain	Fibronectin type III	1	1
HBS1-like domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Galactose mutarotase-like	(Trans)glycosidases	1	1