Domain combination pairs in Apis mellifera 38.2d

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1607 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	354	52
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	294	84
Immunoglobulin	Immunoglobulin	226	96
EGF/Laminin	EGF/Laminin	109	87
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	97	9
Immunoglobulin	Fibronectin type III	94	55
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	83	29
L domain-like	L domain-like	80	42
Fibronectin type III	Fibronectin type III	77	46
EGF/Laminin	Growth factor receptor domain	72	66
TPR-like	TPR-like	69	18
Cadherin-like	Cadherin-like	66	41
HAD-like	Calcium ATPase, transmembrane domain M	65	11
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	65	11
Calcium ATPase, transduction domain A	HAD-like	64	10
Growth factor receptor domain	Growth factor receptor domain	64	55
RNA-binding domain, RBD	RNA-binding domain, RBD	63	18
ABC transporter transmembrane region	ABC transporter transmembrane region	60	7
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	60	2
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	60	8
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	56	6
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	55	5
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	55	5
ARM repeat	ARM repeat	53	23
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	52	6
Voltage-gated potassium channels	Voltage-gated potassium channels	50	10
DBL homology domain (DH-domain)	PH domain-like	49	30
TSP-1 type 1 repeat	TSP-1 type 1 repeat	46	28
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	44	17
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	43	11
Homeodomain-like	Homeodomain-like	42	14
E set domains	E set domains	42	17
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	41	4
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	40	3
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	39	28
(Trans)glycosidases	Chitinase insertion domain	38	10
Second domain of FERM	PH domain-like	38	24
EGF/Laminin	Concanavalin A-like lectins/glucanases	38	30
BAR/IMD domain-like	SH3-domain	38	8
EF-hand	EF-hand	37	17
Spectrin repeat	Spectrin repeat	36	24
MFS general substrate transporter	Kazal-type serine protease inhibitors	36	5
Actin-like ATPase domain	Actin-like ATPase domain	35	8
LDL receptor-like module	LDL receptor-like module	33	29
PH domain-like	PH domain-like	33	23
Periplasmic binding protein-like I	Periplasmic binding protein-like II	33	6
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	32	13
PDZ domain-like	PDZ domain-like	32	16
Cyclin-like	Cyclin-like	31	6
ARM repeat	Protein kinase-like (PK-like)	30	12
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	29	10
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	28	4
Ubiquitin-like	Ubiquitin-like	28	18
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	28	8
Invertebrate chitin-binding proteins	Invertebrate chitin-binding proteins	27	14
RNI-like	L domain-like	27	14
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	27	11
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	27	8
PDZ domain-like	SH3-domain	27	12
Spermadhesin, CUB domain	Spermadhesin, CUB domain	26	20
Ubiquitin-like	PH domain-like	26	18
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	26	4
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	26	7
GroES-like	NAD(P)-binding Rossmann-fold domains	25	6
Translation proteins	EF-G C-terminal domain-like	25	6
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	24	11
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	24	11
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	24	8
Ankyrin repeat	Ankyrin repeat	24	13
FYVE/PHD zinc finger	FYVE/PHD zinc finger	24	13
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	24	6
WW domain	WW domain	24	14
(Trans)glycosidases	Invertebrate chitin-binding proteins	23	8
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	23	9
Chitinase insertion domain	Invertebrate chitin-binding proteins	23	8
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	23	8
Subtilisin-like	Galactose-binding domain-like	23	6
POZ domain	Kelch motif	23	6
WD40 repeat-like	WD40 repeat-like	23	7
Thioredoxin-like	GST C-terminal domain-like	22	2
Ubiquitin-like	Second domain of FERM	22	14
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	22	2
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	21	7
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	21	5
EF-G C-terminal domain-like	EF-G C-terminal domain-like	21	4
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	21	3
SH2 domain	SH3-domain	21	7
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	21	7
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	20	3
Nucleotide cyclase	Nucleotide cyclase	20	3
SH3-domain	SH3-domain	20	11
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	20	4
Calponin-homology domain, CH-domain	Spectrin repeat	19	13
Fibronectin type III	Protein kinase-like (PK-like)	19	10
Sec7 domain	ARM repeat	19	6
F-box domain	RNI-like	19	4
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	19	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	19	6
C-type lectin-like	C-type lectin-like	19	1
ARM repeat	Formin homology 2 domain (FH2 domain)	19	4
Voltage-gated potassium channels	cAMP-binding domain-like	19	5
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	19	6
Cadherin-like	Concanavalin A-like lectins/glucanases	19	14
Cupredoxins	Cupredoxins	19	6
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	19	6
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	19	2
SH2 domain	Protein kinase-like (PK-like)	19	6
POZ domain	Voltage-gated potassium channels	18	3
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	18	2
FYVE/PHD zinc finger	Bromodomain	18	13
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	18	5
LDL receptor-like module	Growth factor receptor domain	18	17
GroEL equatorial domain-like	GroEL apical domain-like	18	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	18	10
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	18	4
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	18	2
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	18	1
Galactose-binding domain-like	Growth factor receptor domain	18	9
Growth factor receptor domain	Protein kinase-like (PK-like)	18	7
LDL receptor-like module	EGF/Laminin	17	17
DPY module	DPY module	17	17
GroEL equatorial domain-like	GroEL-intermediate domain like	17	2
Voltage-gated potassium channels	Periplasmic binding protein-like II	17	5
GroEL-intermediate domain like	GroEL apical domain-like	17	2
Sema domain	Plexin repeat	17	7
EGF/Laminin	YWTD domain	17	14
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	17	7
Protease propeptides/inhibitors	Zn-dependent exopeptidases	17	1
PH domain-like	SH3-domain	17	10
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	17	1
cAMP-binding domain-like	cAMP-binding domain-like	17	6
Spectrin repeat	PH domain-like	16	10
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	16	4
LDL receptor-like module	YWTD domain	16	15
Concanavalin A-like lectins/glucanases	Growth factor receptor domain	16	16
E set domains	Alpha-macroglobulin receptor domain	16	1
E set domains	Terpenoid cyclases/Protein prenyltransferases	16	1
YWTD domain	YWTD domain	16	12
GAF domain-like	HD-domain/PDEase-like	16	5
Calponin-homology domain, CH-domain	PH domain-like	16	8
CoA-dependent acyltransferases	CoA-dependent acyltransferases	16	2
Immunoglobulin	Protein kinase-like (PK-like)	16	13
EGF/Laminin	Spermadhesin, CUB domain	15	9
L domain-like	Toll/Interleukin receptor TIR domain	15	12
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	15	2
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	15	5
SH2 domain	PH domain-like	15	6
Periplasmic binding protein-like I	Voltage-gated potassium channels	15	3
YWTD domain	Growth factor receptor domain	15	14
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	14	4
Translation proteins	Ribosomal protein S5 domain 2-like	14	4
Thiolase-like	Thiolase-like	14	4
PAZ domain	Ribonuclease H-like	14	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	14	3
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	14	11
EF-hand	PLC-like phosphodiesterases	14	7
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	14	2
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	14	3
Protein kinase-like (PK-like)	Nucleotide cyclase	14	5
Immunoglobulin	TSP-1 type 1 repeat	14	8
L domain-like	Immunoglobulin	14	9
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	14	6
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	14	6
Protein kinase-like (PK-like)	PH domain-like	14	6
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	14	6
Myosin rod fragments	Myosin rod fragments	13	6
Ligand-binding domain in the NO signalling and Golgi transport	Nucleotide cyclase	13	1
Cadherin-like	EGF/Laminin	13	8
PreATP-grasp domain	Rudiment single hybrid motif	13	5
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex, superhelical domain	13	4
Growth factor receptor domain	DPY module	13	13
"Winged helix" DNA-binding domain	Periplasmic binding protein-like II	13	1
L domain-like	Protein kinase-like (PK-like)	13	6
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	13	7
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	12	6
Growth factor receptor domain	Fibronectin type III	12	4
PH domain-like	PLC-like phosphodiesterases	12	5
Galactose-binding domain-like	Protein kinase-like (PK-like)	12	4
TSP-1 type 1 repeat	BPTI-like	12	7
SMAD MH1 domain	SMAD/FHA domain	12	2
FnI-like domain	FnI-like domain	12	10
Thioredoxin-like	Thioredoxin-like	12	5
Cysteine-rich domain	Cysteine-rich domain	12	6
GAF domain-like	GAF domain-like	12	3
BAR/IMD domain-like	GTPase activation domain, GAP	12	5
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	12	7
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	12	8
PH domain-like	EF-hand	12	5
Trypsin-like serine proteases	Trypsin-like serine proteases	12	3
RING/U-box	B-box zinc-binding domain	12	6
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	12	2
Tudor/PWWP/MBT	Tudor/PWWP/MBT	11	8
Single hybrid motif	CoA-dependent acyltransferases	11	4
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	11	1
Sema domain	GTPase activation domain, GAP	11	2
Cysteine-rich domain	Protein kinase-like (PK-like)	11	4
Snake toxin-like	Protein kinase-like (PK-like)	11	3
P-loop containing nucleoside triphosphate hydrolases	Protein kinase-like (PK-like)	11	4
Plexin repeat	E set domains	11	2
PH domain-like	(Phosphotyrosine protein) phosphatases II	11	7
E set domains	GTPase activation domain, GAP	11	2
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	11	4
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	11	2
Sema domain	E set domains	11	2
RuvA domain 2-like	Nucleic acid-binding proteins	11	4
Cytochrome P450	Cytochrome P450	11	4
DBL homology domain (DH-domain)	SH3-domain	11	7
Tex N-terminal region-like	RuvA domain 2-like	11	4
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	11	2
Tex N-terminal region-like	Nucleic acid-binding proteins	11	4
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	11	2
RING/U-box	RING/U-box	11	7
Ribonuclease H-like	RuvA domain 2-like	11	4
Plexin repeat	GTPase activation domain, GAP	11	2
Tex N-terminal region-like	Ribonuclease H-like	11	4
RuvA domain 2-like	RuvA domain 2-like	11	4
WD40 repeat-like	RING/U-box	11	3
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	11	5
Ribonuclease H-like	Nucleic acid-binding proteins	11	4
L domain-like	Growth factor receptor domain	11	4
LDL receptor-like module	Spermadhesin, CUB domain	11	10
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	11	7
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	10	4
PreATP-grasp domain	Methylglyoxal synthase-like	10	3
Calpain large subunit, middle domain (domain III)	EF-hand	10	1
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	10	3
Ubiquitin-like	Protein kinase-like (PK-like)	10	4
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	10	6
FF domain	FF domain	10	4
Di-copper centre-containing domain	E set domains	10	5
Periplasmic binding protein-like I	Nucleotide cyclase	10	3
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	10	3
Cysteine proteinases	EF-hand	10	1
ARM repeat	Clathrin adaptor appendage domain	10	3
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	10	3
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	10	4
RING/U-box	Cysteine proteinases	10	4
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	10	3
Complement control module/SCR domain	Complement control module/SCR domain	10	9
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	10	3
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	10	3
Cap-Gly domain	Cap-Gly domain	10	4
lambda repressor-like DNA-binding domains	Homeodomain-like	10	4
Chromo domain-like	Chromo domain-like	10	3
SAM/Pointed domain	"Winged helix" DNA-binding domain	10	2
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	10	3
Ribonuclease H-like	DNA/RNA polymerases	10	3
SH3-domain	Protein kinase-like (PK-like)	10	5
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	10	3
MFS general substrate transporter	MFS general substrate transporter	10	4
SAM/Pointed domain	SAM/Pointed domain	10	4
WW domain	FF domain	10	4
PreATP-grasp domain	PreATP-grasp domain	10	3
SH2 domain	SH2 domain	10	6
PH domain-like	Cysteine-rich domain	10	4
dsRNA-binding domain-like	dsRNA-binding domain-like	10	6
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	9	1
Hemocyanin, N-terminal domain	Di-copper centre-containing domain	9	4
Subtilisin-like	Growth factor receptor domain	9	4
TPR-like	Chaperone J-domain	9	2
Resolvase-like	Homeodomain-like	9	1
(Trans)glycosidases	Glycosyl hydrolase domain	9	4
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	9	2
EF-hand	C-terminal domain of PLC-beta	9	3
PDZ domain-like	PH domain-like	9	5
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	9	6
Cullin homology domain	"Winged helix" DNA-binding domain	9	3
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	9	3
Initiation factor IF2/eIF5b, domain 3	Translation proteins	9	2
FYVE/PHD zinc finger	Tudor/PWWP/MBT	9	6
Hemocyanin, N-terminal domain	E set domains	9	4
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	9	2
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	9	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	9	4
"Winged helix" DNA-binding domain	Chorismate lyase-like	9	1
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	9	4
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	9	2
SH3-domain	GTPase activation domain, GAP	9	4
PH domain-like	C-terminal domain of PLC-beta	9	3
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	9	2
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	9	3
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	9	5
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	9	3
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	9	7
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	9	3
Integrin domains	Integrin domains	9	5
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	9	4
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	9	2
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	9	2
FabD/lysophospholipase-like	ACP-like	8	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	8	3
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	8	2
HMA, heavy metal-associated domain	HAD-like	8	6
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	8	6
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	8	2
FabD/lysophospholipase-like	GroES-like	8	2
Aconitase iron-sulfur domain	LeuD/IlvD-like	8	2
DBL homology domain (DH-domain)	Ras GEF	8	5
POZ domain	POZ domain	8	5
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	8	2
Ubiquitin-like	Ras GEF	8	4
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	8	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	8	2
Tropomyosin	Tropomyosin	8	7
EF-hand	RING/U-box	8	2
FabD/lysophospholipase-like	alpha/beta-Hydrolases	8	2
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	8	3
Thiolase-like	NAD(P)-binding Rossmann-fold domains	8	2
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	8	3
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	8	5
Thiolase-like	FabD/lysophospholipase-like	8	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	8	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	8	3
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	8	4
Calponin-homology domain, CH-domain	E set domains	8	6
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	8	3
PurM N-terminal domain-like	PurM C-terminal domain-like	8	4
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	8	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	8	1
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	8	3
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	8	2
NAD(P)-binding Rossmann-fold domains	ACP-like	8	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	8	2
IP3 receptor type 1 binding core, domain 2	EF-hand	8	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	8	3
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	8	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	8	2
WD40 repeat-like	TPR-like	8	5
TB module/8-cys domain	Growth factor receptor domain	8	8
MIR domain	MIR domain	8	3
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	2
Zn-finger domain of Sec23/24	vWA-like	8	3
MIR domain	IP3 receptor type 1 binding core, domain 2	8	3
MIR domain	Concanavalin A-like lectins/glucanases	8	3
beta-sandwich domain of Sec23/24	vWA-like	8	3
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	8	6
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	8	3
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	8	1
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	8	6
BRCT domain	BRCT domain	8	7
MIR domain	EF-hand	8	3
Ankyrin repeat	SAM/Pointed domain	8	3
Thiolase-like	alpha/beta-Hydrolases	8	2
Concanavalin A-like lectins/glucanases	IP3 receptor type 1 binding core, domain 2	8	3
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	8	2
Probable ACP-binding domain of malonyl-CoA ACP transacylase	GroES-like	8	2
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	8	3
cAMP-binding domain-like	Protein kinase-like (PK-like)	8	1
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	8	2
ENTH/VHS domain	GAT-like domain	8	2
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	8	4
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	8	6
Thiolase-like	GroES-like	8	2
ARM repeat	Concanavalin A-like lectins/glucanases	8	3
PH domain-like	GTPase activation domain, GAP	8	7
ACP-like	alpha/beta-Hydrolases	8	2
FabD/lysophospholipase-like	NAD(P)-binding Rossmann-fold domains	8	2
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	8	2
NAD(P)-binding Rossmann-fold domains	alpha/beta-Hydrolases	8	2
PH domain-like	ArfGap/RecO-like zinc finger	8	5
Probable ACP-binding domain of malonyl-CoA ACP transacylase	alpha/beta-Hydrolases	8	2
Concanavalin A-like lectins/glucanases	EF-hand	8	3
PH domain-like	Ras GEF	8	5
Thiolase-like	ACP-like	8	2
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	8	2
Probable ACP-binding domain of malonyl-CoA ACP transacylase	NAD(P)-binding Rossmann-fold domains	8	2
Kringle-like	Protein kinase-like (PK-like)	8	2
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	8	2
GroES-like	ACP-like	8	2
Integrin alpha N-terminal domain	Integrin domains	8	4
PHM/PNGase F	PHM/PNGase F	8	3
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	2
Transmembrane di-heme cytochromes	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	8	1
TB module/8-cys domain	TB module/8-cys domain	8	8
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	8	3
GroES-like	alpha/beta-Hydrolases	8	2
EGF/Laminin	TB module/8-cys domain	8	8
Probable ACP-binding domain of malonyl-CoA ACP transacylase	ACP-like	8	2
WW domain	Hect, E3 ligase catalytic domain	8	5
Calponin-homology domain, CH-domain	SH3-domain	7	3
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	7	3
Chitinase insertion domain	Chitinase insertion domain	7	6
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	7	5
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	7	3
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	7	1
ADC-like	P-loop containing nucleoside triphosphate hydrolases	7	3
vWA-like	Helical domain of Sec23/24	7	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	7	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	7	2
L domain-like	UBA-like	7	2
Glucocorticoid receptor-like (DNA-binding domain)	beta-beta-alpha zinc fingers	7	3
L domain-like	NTF2-like	7	2
Sec63 N-terminal domain-like	E set domains	7	3
HR1 repeat	Protein kinase-like (PK-like)	7	5
PDZ domain-like	Ubiquitin-like	7	4
Nucleic acid-binding proteins	Nucleic acid-binding proteins	7	4
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	7	3
UBA-like	Ubiquitin-like	7	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	7	2
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	7	5
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	7	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	7	1
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	7	2
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	7	3
Actin depolymerizing proteins	Actin depolymerizing proteins	7	3
Periplasmic binding protein-like II	Periplasmic binding protein-like II	7	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	7	1
Growth factor receptor domain	Spermadhesin, CUB domain	7	4
DNA clamp	DNA clamp	7	1
Concanavalin A-like lectins/glucanases	RING/U-box	7	3
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	7	1
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	7	4
P-loop containing nucleoside triphosphate hydrolases	EF-hand	7	3
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	7	5
(Trans)glycosidases	(Trans)glycosidases	7	6
ADC-like	Cdc48 domain 2-like	7	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	7	2
Galactose-binding domain-like	(Trans)glycosidases	7	4
BAR/IMD domain-like	PH domain-like	7	4
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	7	6
HR1 repeat	HR1 repeat	7	5
CCCH zinc finger	RING/U-box	7	3
FYVE/PHD zinc finger	SET domain	7	5
Galactose-binding domain-like	Fibronectin type III	7	3
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	7	1
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	7	5
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	7	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	7	4
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	7	5
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	2
POZ domain	Galactose oxidase, central domain	7	6
Kazal-type serine protease inhibitors	EF-hand	7	5
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	7	1
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	7	2
NTF2-like	UBA-like	7	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	7	1
F-box domain	WD40 repeat-like	6	3
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	6	2
Class I glutamine amidotransferase-like	PreATP-grasp domain	6	2
Rudiment single hybrid motif	PurM N-terminal domain-like	6	2
Surp module (SWAP domain)	Surp module (SWAP domain)	6	3
(Trans)glycosidases	Six-hairpin glycosidases	6	1
PR-1-like	Crisp domain-like	6	2
BPTI-like	BPTI-like	6	6
L domain-like	Family A G protein-coupled receptor-like	6	6
RuvA domain 2-like	SH2 domain	6	3
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	6	3
RNA-binding domain, RBD	SPOC domain-like	6	3
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	6	2
PreATP-grasp domain	PurM C-terminal domain-like	6	2
YjgF-like	YjgF-like	6	3
Nucleic acid-binding proteins	SH2 domain	6	3
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	6	4
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	6	4
ARM repeat	Subdomain of clathrin and coatomer appendage domain	6	2
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	6	2
Protease propeptides/inhibitors	Galactose-binding domain-like	6	1
Bromodomain	Tudor/PWWP/MBT	6	3
Family A G protein-coupled receptor-like	Family A G protein-coupled receptor-like	6	2
Rudiment single hybrid motif	PurM C-terminal domain-like	6	2
Calponin-homology domain, CH-domain	EF-hand	6	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	6	3
P-loop containing nucleoside triphosphate hydrolases	PUA domain-like	6	2
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	6	2
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	6	3
CalX-like	CalX-like	6	1
Cysteine-rich domain	Ubiquitin-like	6	3
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	6	3
Rudiment single hybrid motif	Single hybrid motif	6	2
FYVE/PHD zinc finger	Clavaminate synthase-like	6	4
Tex N-terminal region-like	SH2 domain	6	3
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	6	3
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	6	3
SH2 domain	SOCS box-like	6	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	6	2
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	6	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	6	1
B-box zinc-binding domain	NHL repeat	6	3
RING/U-box	Homeodomain-like	6	4
BAR/IMD domain-like	Ankyrin repeat	6	3
vWA-like	EGF/Laminin	6	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	6	2
RING/U-box	PUA domain-like	6	5
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	6	2
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	6	3
PreATP-grasp domain	PurM N-terminal domain-like	6	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	6	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	6	3
GAT-like domain	Clathrin adaptor appendage domain	6	1
PH domain-like	Ankyrin repeat	6	3
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	6	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	6	3
Invertebrate chitin-binding proteins	LDL receptor-like module	6	4
TPR-like	RING/U-box	6	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	6	2
GTPase activation domain, GAP	RGC domain-like	6	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	6	2
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	6	2
EF-hand	Riboflavin synthase domain-like	6	3
CCCH zinc finger	CCCH zinc finger	6	5
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	6	3
Phospholipase D/nuclease	Phospholipase D/nuclease	6	3
Protease propeptides/inhibitors	Subtilisin-like	6	1
Enolase N-terminal domain-like	Enolase C-terminal domain-like	6	1
RNA-binding domain, RBD	UBA-like	6	3
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	6	3
Myosin rod fragments	Tropomyosin	6	6
Nucleotidylyl transferase	Alpha-L RNA-binding motif	6	1
ENTH/VHS domain	Clathrin adaptor appendage domain	6	1
Galactose-binding domain-like	Concanavalin A-like lectins/glucanases	6	4
Ribonuclease H-like	SH2 domain	6	3
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	6	4
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	2
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	6	2
Spectrin repeat	EF-hand	6	4
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	6	4
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	6	2
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	6	2
PreATP-grasp domain	Single hybrid motif	6	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	6	3
LDL receptor-like module	Concanavalin A-like lectins/glucanases	6	6
Adenine nucleotide alpha hydrolases-like	YjgF-like	6	3
Calponin-homology domain, CH-domain	SH2 domain	5	1
Spectrin repeat	SH3-domain	5	5
GTPase activation domain, GAP	Bet v1-like	5	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Chaperone J-domain	5	3
Bet v1-like	HAD-like	5	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	5	3
PH domain-like	WD40 repeat-like	5	2
EF-hand	SH3-domain	5	4
Fibronectin type III	Concanavalin A-like lectins/glucanases	5	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	5	1
Integrin domains	EGF/Laminin	5	2
CRAL/TRIO domain	PH domain-like	5	3
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	5	3
Carbamoyl phosphate synthetase, large subunit connection domain	Composite domain of metallo-dependent hydrolases	5	1
TGS-like	Class II aaRS and biotin synthetases	5	2
Sec7 domain	PH domain-like	5	2
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	5	1
Complement control module/SCR domain	Growth factor receptor domain	5	5
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	5	4
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Composite domain of metallo-dependent hydrolases	5	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	5	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	5	1
SET domain	TPR-like	5	3
Cullin repeat-like	Cullin homology domain	5	2
EGF/Laminin	Ankyrin repeat	5	5
p53-like transcription factors	E set domains	5	3
Second domain of FERM	FAT domain of focal adhesion kinase	5	3
BRK domain-like	P-loop containing nucleoside triphosphate hydrolases	5	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	5	2
EGF/Laminin	Calcium-dependent phosphotriesterase	5	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	5	3
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	5	1
PreATP-grasp domain	Metallo-dependent hydrolases	5	1
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	5	4
TGS-like	ThrRS/AlaRS common domain	5	2
vWA-like	Integrin beta tail domain	5	2
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	5	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	5	1
B-box zinc-binding domain	Concanavalin A-like lectins/glucanases	5	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	5	3
B-box zinc-binding domain	Fibronectin type III	5	1
Integrin domains	Integrin beta tail domain	5	2
Immunoglobulin	Growth factor receptor domain	5	5
Growth factor receptor domain	Ankyrin repeat	5	5
POZ domain	Ankyrin repeat	5	3
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	5	2
PreATP-grasp domain	Composite domain of metallo-dependent hydrolases	5	1
TGS-like	Class II aaRS ABD-related	5	2
Galactose-binding domain-like	Galactose-binding domain-like	5	5
PH domain-like	FAT domain of focal adhesion kinase	5	3
BRK domain-like	Bromodomain	5	1
PH domain-like	Phospholipase D/nuclease	5	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	5	2
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	2
Carboxypeptidase regulatory domain-like	Calcium-dependent phosphotriesterase	5	1
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	5	4
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	5	2
RING/U-box	DUSP-like	5	1
SRCR-like	Trypsin-like serine proteases	5	5
lambda repressor-like DNA-binding domains	LexA/Signal peptidase	5	1
EGF/Laminin	DPY module	5	5
Kelch motif	Kelch motif	5	2
NAD(P)-binding Rossmann-fold domains	SCP-like	5	2
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	5	1
Glutathione synthetase ATP-binding domain-like	Composite domain of metallo-dependent hydrolases	5	1
PYP-like sensor domain (PAS domain)	HD-domain/PDEase-like	5	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	5	3
Methylglyoxal synthase-like	Metallo-dependent hydrolases	5	1
HIT/MYND zinc finger-like	TPR-like	5	3
A DNA-binding domain in eukaryotic transcription factors	Leucine zipper domain	5	4
PH domain-like	BEACH domain	5	3
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	5	1
Galactose-binding domain-like	Complement control module/SCR domain	5	5
EGF/Laminin	Carboxypeptidase regulatory domain-like	5	1
CBS-domain pair	CBS-domain pair	5	1
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	5	2
LDL receptor-like module	Trypsin-like serine proteases	5	5
PX domain	Phospholipase D/nuclease	5	2
ARM repeat	WD40 repeat-like	5	3
DBL homology domain (DH-domain)	SH2 domain	5	1
EGF/Laminin	Notch domain	5	5
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	5	3
Chaperone J-domain	Homeodomain-like	5	1
ARID-like	Clavaminate synthase-like	5	3
CRAL/TRIO domain	Spectrin repeat	5	3
RING/U-box	TRAF domain-like	5	3
vWA-like	Integrin domains	5	2
CRAL/TRIO domain	DBL homology domain (DH-domain)	5	3
PX domain	PH domain-like	5	2
BRCT domain	DBL homology domain (DH-domain)	5	4
RING/U-box	Fibronectin type III	5	1
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	5	2
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	5	1
L domain-like	Fibronectin type III	5	1
Cyclophilin-like	TPR-like	5	1
Composite domain of metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	5	1
Notch domain	Notch domain	5	5
EGF/Laminin	Integrin beta tail domain	5	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	5	1
Bromodomain	Bromodomain	5	3
Methylglyoxal synthase-like	Composite domain of metallo-dependent hydrolases	5	1
FYVE/PHD zinc finger	Chromo domain-like	5	1
SNARE-like	SNARE fusion complex	5	2
Zn-dependent exopeptidases	Zn-dependent exopeptidases	5	3
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	5	1
Notch domain	Ankyrin repeat	5	5
LDL receptor-like module	Immunoglobulin	5	5
Spectrin repeat	DBL homology domain (DH-domain)	5	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	5	1
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	5	3
Growth factor receptor domain	Notch domain	5	5
ARM repeat	Hect, E3 ligase catalytic domain	5	2
Tudor/PWWP/MBT	SAM/Pointed domain	5	3
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	5	1
Immunoglobulin	EGF/Laminin	5	5
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	5	1
HIT/MYND zinc finger-like	SET domain	5	3
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	5	2
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	5	1
DUSP-like	DUSP-like	5	1
Cysteine proteinases	DUSP-like	5	1
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	5	2
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	5	2
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	5	3
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	5	2
Protein kinase-like (PK-like)	PDZ domain-like	5	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	5	2
(Phosphotyrosine protein) phosphatases II	Chaperone J-domain	5	3
Class I glutamine amidotransferase-like	Composite domain of metallo-dependent hydrolases	5	1
Second domain of FERM	Protein kinase-like (PK-like)	5	3
FAS1 domain	FAS1 domain	5	3
Histone-fold	DBL homology domain (DH-domain)	4	4
Second domain of FERM	Moesin tail domain	4	2
Galactose-binding domain-like	C-type lectin-like	4	4
PreATP-grasp domain	post-HMGL domain-like	4	1
Chaperone J-domain	beta-beta-alpha zinc fingers	4	1
Histone-fold	PH domain-like	4	4
RUN domain-like	RUN domain-like	4	1
GFP-like	YWTD domain	4	4
Surp module (SWAP domain)	Ubiquitin-like	4	1
Concanavalin A-like lectins/glucanases	FnI-like domain	4	4
Ubiquitin-like	FAT domain of focal adhesion kinase	4	2
P-loop containing nucleoside triphosphate hydrolases	FF domain	4	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	4	2
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	4	2
Protein kinase-like (PK-like)	SAM/Pointed domain	4	2
Nucleic acid-binding proteins	Translation proteins SH3-like domain	4	2
post-HMGL domain-like	Single hybrid motif	4	1
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	4	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	4	1
PH domain-like	Moesin tail domain	4	2
C-type lectin-like	Complement control module/SCR domain	4	4
lambda repressor-like DNA-binding domains	Periplasmic binding protein-like I	4	1
"Winged helix" DNA-binding domain	E set domains	4	2
PUA domain-like	Ribosomal protein S5 domain 2-like	4	1
Cysteine-rich domain	RNA-binding domain, RBD	4	2
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	4	1
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	4	2
PH domain-like	Ypt/Rab-GAP domain of gyp1p	4	3
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	4	2
SAP domain	Concanavalin A-like lectins/glucanases	4	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Starch-binding domain-like	Starch-binding domain-like	4	2
PreATP-grasp domain	Aldolase	4	1
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	4	2
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	4	1
alpha-helical ferredoxin	Nucleotide-binding domain	4	2
Aldolase	post-HMGL domain-like	4	1
Invertebrate chitin-binding proteins	Glycoside hydrolase/deacetylase	4	2
PX domain	SH3-domain	4	3
SH2 domain	GTPase activation domain, GAP	4	2
TAZ domain	Kix domain of CBP (creb binding protein)	4	4
FKBP-like	TPR-like	4	2
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	4	3
ARID-like	FYVE/PHD zinc finger	4	2
Elafin-like	Immunoglobulin	4	4
ClpS-like	"Winged helix" DNA-binding domain	4	1
Ubiquitin-like	ARM repeat	4	1
Aldolase	Single hybrid motif	4	1
Transglutaminase, two C-terminal domains	Transglutaminase, two C-terminal domains	4	3
DNA-binding domain	FYVE/PHD zinc finger	4	3
L domain-like	P-loop containing nucleoside triphosphate hydrolases	4	4
PDZ domain-like	Glucocorticoid receptor-like (DNA-binding domain)	4	2
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	4	1
S15/NS1 RNA-binding domain	C-terminal domain of ProRS	4	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	4	1
RNA-binding domain, RBD	PWI domain	4	1
HCP-like	HCP-like	4	3
Rudiment single hybrid motif	Aldolase	4	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	4	2
GST C-terminal domain-like	S15/NS1 RNA-binding domain	4	2
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
RNA-binding domain, RBD	NAD kinase/diacylglycerol kinase-like	4	2
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	4	1
Histone-fold	Ras GEF	4	4
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	4	1
BPTI-like	Immunoglobulin	4	4
Cullin repeat-like	"Winged helix" DNA-binding domain	4	1
P-loop containing nucleoside triphosphate hydrolases	E set domains	4	2
L27 domain	PDZ domain-like	4	3
RNase III domain-like	dsRNA-binding domain-like	4	3
Cyclophilin-like	RNA-binding domain, RBD	4	2
Tudor/PWWP/MBT	HIT/MYND zinc finger-like	4	2
FF domain	GTPase activation domain, GAP	4	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	4	2
WD40 repeat-like	SNARE fusion complex	4	2
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	4	3
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	4	2
LDL receptor-like module	Glycoside hydrolase/deacetylase	4	2
Plexin repeat	vWA-like	4	2
PGBD-like	Metalloproteases ("zincins"), catalytic domain	4	2
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	4	1
Protein kinase-like (PK-like)	Chaperone J-domain	4	2
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	4	1
DNA-binding domain	Bromodomain	4	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	4	3
GFP-like	Growth factor receptor domain	4	4
PAH2 domain	PAH2 domain	4	1
Glutathione synthetase ATP-binding domain-like	Aldolase	4	1
RNA-binding domain, RBD	L domain-like	4	1
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	4	2
Bromodomain	HIT/MYND zinc finger-like	4	2
MgtE membrane domain-like	MgtE membrane domain-like	4	1
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	4	2
FYVE/PHD zinc finger	HIT/MYND zinc finger-like	4	2
P-loop containing nucleoside triphosphate hydrolases	TGS-like	4	1
Class II aaRS ABD-related	C-terminal domain of ProRS	4	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	4	2
P-loop containing nucleoside triphosphate hydrolases	POZ domain	4	2
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	4	2
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	4	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	4	2
PDZ domain-like	DBL homology domain (DH-domain)	4	3
EGF/Laminin	Galactose-binding domain-like	4	4
Thioredoxin-like	Six-hairpin glycosidases	4	1
FnI-like domain	Growth factor receptor domain	4	4
EGF/Laminin	Complement control module/SCR domain	4	4
PH domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	4	3
Cysteine proteinases	Transglutaminase, two C-terminal domains	4	3
Ubiquitin-like	RNA-binding domain, RBD	4	2
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	4	1
PH domain-like	ARM repeat	4	2
Rudiment single hybrid motif	post-HMGL domain-like	4	1
PH domain-like	Oxysterol-binding protein-like	4	3
RNA-binding domain, RBD	NTF2-like	4	1
Galactose oxidase, central domain	Kelch motif	4	3
TRAF domain-like	Cysteine proteinases	4	1
Clc chloride channel	CBS-domain pair	4	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	4	1
Regulator of G-protein signaling, RGS	PX domain	4	3
GST C-terminal domain-like	Nucleotidylyl transferase	4	2
RNase III domain-like	RNase III domain-like	4	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	4	2
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	4	1
BPTI-like	Elafin-like	4	4
TSP-1 type 1 repeat	Elafin-like	4	4
Ankyrin repeat	Mib/herc2 domain-like	4	2
ClpP/crotonase	ClpP/crotonase	4	2
LDL receptor-like module	Mannose 6-phosphate receptor domain	4	2
WW domain	PDZ domain-like	4	3
SAP domain	P-loop containing nucleoside triphosphate hydrolases	4	2
EF-hand	Tropomyosin	3	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	3	1
LDL receptor-like module	EF-hand	3	1
PUA domain-like	SWIB/MDM2 domain	3	2
RING/U-box	Ankyrin repeat	3	2
EF-hand	Mitochondrial carrier	3	2
BEACH domain	WD40 repeat-like	3	1
SAM/Pointed domain	ADP-ribosylation	3	1
Thioredoxin-like	eEF1-gamma domain	3	1
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	3	1
PLP-dependent transferases	PLP-dependent transferases	3	2
Acetyl-CoA synthetase-like	ACP-like	3	2
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	3	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	3	1
RNA-binding domain, RBD	Eukaryotic type KH-domain (KH-domain type I)	3	2
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	3	2
GST C-terminal domain-like	Class II aaRS ABD-related	3	1
Tudor/PWWP/MBT	ARID-like	3	2
Invasin/intimin cell-adhesion fragments	Invasin/intimin cell-adhesion fragments	3	1
E set domains	Cysteine proteinases	3	2
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	3	1
GST C-terminal domain-like	Ribosomal protein L25-like	3	1
GroES-like	GroES-like	3	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	3	1
Spermadhesin, CUB domain	Trypsin-like serine proteases	3	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	VPS9 domain	3	2
Ubiquitin-like	RING/U-box	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Cysteine-rich domain	3	2
PH domain-like	VPS9 domain	3	2
Amyloid beta a4 protein copper binding domain (domain 2)	CAPPD, an extracellular domain of amyloid beta A4 protein	3	2
Putative DNA-binding domain	SAND domain-like	3	3
Ubiquitin-like	DBL homology domain (DH-domain)	3	3
PurM C-terminal domain-like	Formyltransferase	3	1
FnI-like domain	EGF/Laminin	3	3
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	3	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	3	2
ARID-like	ARM repeat	3	2
Complement control module/SCR domain	Concanavalin A-like lectins/glucanases	3	3
POZ domain	Homeodomain-like	3	2
FMN-linked oxidoreductases	alpha-helical ferredoxin	3	1
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	3	2
TAFH domain-like	HIT/MYND zinc finger-like	3	2
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	3	2
POZ domain	beta-beta-alpha zinc fingers	3	3
DPP6 N-terminal domain-like	Tubby C-terminal domain-like	3	2
Kringle-like	Kringle-like	3	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	3	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	3	2
MAST3 pre-PK domain-like	PDZ domain-like	3	1
Nucleotidylyl transferase	Class II aaRS ABD-related	3	1
Nucleotidylyl transferase	C-terminal domain of ProRS	3	1
SNARE fusion complex	SNARE fusion complex	3	1
Guanido kinase N-terminal domain	Glutamine synthetase/guanido kinase	3	1
p53-like transcription factors	SH2 domain	3	1
A heparin-binding domain	CAPPD, an extracellular domain of amyloid beta A4 protein	3	2
L domain-like	Heme-dependent peroxidases	3	2
Ankyrin repeat	TPR-like	3	2
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	3	2
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	3	1
Hairpin loop containing domain-like	Hairpin loop containing domain-like	3	2
L domain-like	Outer arm dynein light chain 1	3	2
FYVE/PHD zinc finger	"Winged helix" DNA-binding domain	3	2
YVTN repeat-like/Quinoprotein amine dehydrogenase	Quinoprotein alcohol dehydrogenase-like	3	3
PRP4-like	WD40 repeat-like	3	2
CCCH zinc finger	RNA-binding domain, RBD	3	2
Ankyrin repeat	Voltage-gated potassium channels	3	1
TPR-like	PH domain-like	3	2
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	3	2
Glucocorticoid receptor-like (DNA-binding domain)	Putative DNA-binding domain	3	2
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	3	1
DEATH domain	Protein kinase-like (PK-like)	3	1
Protein kinase-like (PK-like)	Polo-box domain	3	2
SNARE-like	Domain of the SRP/SRP receptor G-proteins	3	1
Thyroglobulin type-1 domain	EF-hand	3	3
PDZ domain-like	Ras GEF	3	2
GST C-terminal domain-like	C-terminal domain of ProRS	3	1
Tudor/PWWP/MBT	SET domain	3	3
Immunoglobulin	DEATH domain	3	1
Ribosomal protein L25-like	C-terminal domain of ProRS	3	1
TSP-1 type 1 repeat	DEATH domain	3	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	3	2
Leukotriene A4 hydrolase N-terminal domain	Leukotriene A4 hydrolase N-terminal domain	3	1
L27 domain	P-loop containing nucleoside triphosphate hydrolases	3	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	3	2
Ubiquitin-like	Cysteine proteinases	3	2
Rudiment single hybrid motif	Formyltransferase	3	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	3	2
PGBD-like	Hemopexin-like domain	3	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	3	1
SMAD/FHA domain	PH domain-like	3	2
Second domain of FERM	Second domain of FERM	3	3
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	3	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	3	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	3	3
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
Ankyrin repeat	Protein kinase-like (PK-like)	3	3
Kelch motif	Fibronectin type III	3	2
Spermadhesin, CUB domain	Kelch motif	3	2
Transcription factor STAT-4 N-domain	STAT	3	1
Putative isomerase YbhE	WD40 repeat-like	3	3
L27 domain	SH3-domain	3	2
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	3	2
FMN-linked oxidoreductases	Nucleotide-binding domain	3	1
Glutathione synthetase ATP-binding domain-like	Formyltransferase	3	1
PK beta-barrel domain-like	PK C-terminal domain-like	3	2
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	3	2
S15/NS1 RNA-binding domain	S15/NS1 RNA-binding domain	3	1
Transcription factor STAT-4 N-domain	p53-like transcription factors	3	1
GST C-terminal domain-like	Class II aaRS and biotin synthetases	3	1
beta-beta-alpha zinc fingers	WW domain	3	1
PurM N-terminal domain-like	Formyltransferase	3	1
STAT	p53-like transcription factors	3	1
LDL receptor-like module	SRCR-like	3	3
RCC1/BLIP-II	RCC1/BLIP-II	3	2
Cysteine proteinases	Ribonuclease H-like	3	2
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	3	1
Transcription factor STAT-4 N-domain	SH2 domain	3	1
B-box zinc-binding domain	Bromodomain	3	2
B-box zinc-binding domain	FYVE/PHD zinc finger	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	2
C-terminal UvrC-binding domain of UvrB	RuvA domain 2-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	3	1
FKBP-like	FKBP-like	3	1
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	3	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	3	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	3	1
CCCH zinc finger	Retrovirus zinc finger-like domains	3	2
EF-hand	Mannose 6-phosphate receptor domain	3	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	3	1
Cna protein B-type domain	Starch-binding domain-like	3	1
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	3	1
Ankyrin repeat	Hect, E3 ligase catalytic domain	3	1
A heparin-binding domain	Amyloid beta a4 protein copper binding domain (domain 2)	3	2
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	3	3
Flavoproteins	Riboflavin synthase domain-like	3	2
Ankyrin repeat	SET domain	3	1
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	3	1
Regulator of G-protein signaling, RGS	Ubiquitin-like	3	3
Kelch motif	EGF/Laminin	3	2
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	3	2
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	3	1
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	2
RING/U-box	Cyclophilin-like	3	3
Chaperone J-domain	Sec63 N-terminal domain-like	3	1
Ribosomal protein L25-like	S15/NS1 RNA-binding domain	3	1
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	1
WD40 repeat-like	Cysteine proteinases	3	2
Actin depolymerizing proteins	SH3-domain	3	1
PABC (PABP) domain	Hect, E3 ligase catalytic domain	3	2
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	3	1
RING/U-box	NHL repeat	3	2
DEK C-terminal domain	SWIB/MDM2 domain	3	1
Voltage-gated potassium channels	E set domains	3	2
ARM repeat	Mib/herc2 domain-like	3	1
cAMP-binding domain-like	FabD/lysophospholipase-like	3	2
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	3	2
Chaperone J-domain	E set domains	3	1
Methylated DNA-protein cysteine methyltransferase domain	Methylated DNA-protein cysteine methyltransferase, C-terminal domain	3	1
Immunoglobulin	Concanavalin A-like lectins/glucanases	3	3
Clathrin heavy-chain terminal domain	ARM repeat	3	1
Ankyrin repeat	ADP-ribosylation	3	1
GroEL apical domain-like	SAICAR synthase-like	3	2
Mib/herc2 domain-like	Hect, E3 ligase catalytic domain	3	1
Ribosomal protein L25-like	Class II aaRS ABD-related	3	1
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	3	1
Hermes dimerisation domain	Ribonuclease H-like	3	1
Ribosomal protein L6	Ribosomal protein L6	3	1
DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	3	1
Smc hinge domain	Tropomyosin	3	3
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	3	1
ISP domain	FAD/NAD(P)-binding domain	3	1
PH domain-like	BSD domain-like	3	1
PH domain-like	Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain	3	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	3	1
WD40 repeat-like	Ribonuclease H-like	3	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	3	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
Ankyrin repeat	DEATH domain	3	1
cAMP-binding domain-like	Ras GEF	3	2
Chromo domain-like	SET domain	3	2
STAT	SH2 domain	3	1
E set domains	Transglutaminase, two C-terminal domains	3	2
Immunoglobulin	Heme-dependent peroxidases	3	2
cAMP-binding domain-like	Ubiquitin-like	3	2
WD40 repeat-like	UBC-like	3	1
BSD domain-like	BSD domain-like	3	1
alpha/beta knot	Nucleic acid-binding proteins	3	2
SNF-like	SNF-like	3	1
PreATP-grasp domain	Formyltransferase	3	1
ARM repeat	Ankyrin repeat	3	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	3	1
PH domain-like	Ran binding protein zinc finger-like	3	2
UBA-like	Thioredoxin-like	3	2
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	3	3
GST C-terminal domain-like	eEF1-gamma domain	3	1
FYVE/PHD zinc finger	RING/U-box	3	2
GTPase activation domain, GAP	CRAL/TRIO domain	3	3
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
Thyroglobulin type-1 domain	Thyroglobulin type-1 domain	3	3
cAMP-binding domain-like	PDZ domain-like	3	2
Nucleotidylyl transferase	Ribosomal protein L25-like	3	1
POZ domain	Skp1 dimerisation domain-like	3	1
HSP20-like chaperones	TPR-like	3	1
Kazal-type serine protease inhibitors	Thyroglobulin type-1 domain	3	3
P-loop containing nucleoside triphosphate hydrolases	vWA-like	3	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	3	1
SEA domain	EGF/Laminin	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	1
DNase I-like	DNA/RNA polymerases	2	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	2	1
RNA-binding domain, RBD	Class II aaRS ABD-related	2	2
Spermadhesin, CUB domain	Concanavalin A-like lectins/glucanases	2	2
PUA domain-like	Nucleotidylyl transferase	2	1
Spermadhesin, CUB domain	Complement control module/SCR domain	2	2
SH2 domain	Ras GEF	2	1
Plexin repeat	EGF/Laminin	2	1
P-loop containing nucleoside triphosphate hydrolases	Nucleotidylyl transferase	2	1
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	2	2
FAD-linked reductases, C-terminal domain	FAD-linked reductases, C-terminal domain	2	1
Methuselah ectodomain	Family A G protein-coupled receptor-like	2	1
MIR domain	ARM repeat	2	1
Plexin repeat	TSP-1 type 1 repeat	2	2
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	2	2
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	1
Macro domain-like	Zn-dependent exopeptidases	2	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Spermadhesin, CUB domain	Galactose-binding domain-like	2	2
PLC-like phosphodiesterases	Ubiquitin-like	2	2
BRCT domain	WGR domain-like	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
Ribonuclease H-like	HRDC-like	2	2
FAD-linked reductases, C-terminal domain	EF-hand	2	2
Kazal-type serine protease inhibitors	Immunoglobulin	2	1
Concanavalin A-like lectins/glucanases	PH domain-like	2	2
Rudiment single hybrid motif	ClpP/crotonase	2	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	2	2
LDL receptor-like module	Terpenoid cyclases/Protein prenyltransferases	2	2
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	2	1
SWIB/MDM2 domain	eIF1-like	2	1
TATA-box binding protein-like	TATA-box binding protein-like	2	2
Ubiquitin-like	Ran binding protein zinc finger-like	2	1
ARM repeat	EF-hand	2	1
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	2	2
Glucocorticoid receptor-like (DNA-binding domain)	Ubiquitin-like	2	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	2	1
Ubiquitin-like	FYVE/PHD zinc finger	2	1
ISP transmembrane anchor	ISP domain	2	2
A middle domain of Talin 1	I/LWEQ domain	2	1
"Winged helix" DNA-binding domain	occludin/ELL-like	2	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	2	1
CBS-domain pair	cAMP-binding domain-like	2	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	2	1
GST C-terminal domain-like	eEF-1beta-like	2	1
Galactose-binding domain-like	RING/U-box	2	1
beta-beta-alpha zinc fingers	Homeodomain-like	2	2
lambda repressor-like DNA-binding domains	lambda repressor-like DNA-binding domains	2	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	2	1
RCC1/BLIP-II	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	2	2
CHY zinc finger-like	Zinc hairpin stack	2	1
PUA domain-like	eIF1-like	2	1
Cadherin-like	Growth factor receptor domain	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
CCHHC domain	CCHHC domain	2	2
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	2	1
LDL receptor-like module	Family A G protein-coupled receptor-like	2	2
DNA-binding protein LAG-1 (CSL)	E set domains	2	2
Acyl-CoA binding protein	Supernatant protein factor (SPF), C-terminal domain	2	2
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	2	2
E set domains	Galactose-binding domain-like	2	1
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	2	2
SRCR-like	SRCR-like	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	2	1
EF-hand	Isochorismatase-like hydrolases	2	1
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	2	1
PAZ domain	RNase III domain-like	2	2
DBL homology domain (DH-domain)	WD40 repeat-like	2	1
Ubiquitin-like	Zn-binding ribosomal proteins	2	1
Second domain of FERM	alpha-catenin/vinculin-like	2	1
C-type lectin-like	Immunoglobulin	2	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	2	1
LDL receptor-like module	L domain-like	2	2
Mib/herc2 domain-like	Mib/herc2 domain-like	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	2
FMN-linked oxidoreductases	dsRNA-binding domain-like	2	1
Ankyrin repeat	FabD/lysophospholipase-like	2	2
Tetrapyrrole methylase	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	2	1
LDL receptor-like module	Protein kinase-like (PK-like)	2	2
LDL receptor-like module	Complement control module/SCR domain	2	2
PH domain-like	A middle domain of Talin 1	2	1
WWE domain	Hect, E3 ligase catalytic domain	2	1
B-box zinc-binding domain	TRAF domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	SOCS box-like	2	1
Ankyrin repeat	L domain-like	2	2
Serine protease inhibitors	FnI-like domain	2	2
Ankyrin repeat	SH3-domain	2	2
PTS-regulatory domain, PRD	PTS system IIB component-like	2	1
FYVE/PHD zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
LDL receptor-like module	Alpha-macroglobulin receptor domain	2	2
BRCT domain	Homeodomain-like	2	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	2	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	2	1
PP2C-like	PP2C-like	2	1
GTPase activation domain, GAP	VPS9 domain	2	2
FYVE/PHD zinc finger	SAICAR synthase-like	2	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	2	2
PreATP-grasp domain	ClpP/crotonase	2	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Formyltransferase	ALDH-like	2	1
HCP-like	SAM/Pointed domain	2	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	2	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	2	2
BRCT domain	ADP-ribosylation	2	1
Kazal-type serine protease inhibitors	YVTN repeat-like/Quinoprotein amine dehydrogenase	2	1
EF-hand	Immunoglobulin	2	1
Phosphofructokinase	Phosphofructokinase	2	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	2	1
RNA-binding domain, RBD	PABC (PABP) domain	2	1
Galactose-binding domain-like	BRCT domain	2	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
PH domain-like	alpha-catenin/vinculin-like	2	1
Ankyrin repeat	PDZ domain-like	2	2
I/LWEQ domain	I/LWEQ domain	2	1
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	2	1
Thioredoxin-like	Ubiquitin-like	2	1
PH domain-like	Quinoprotein alcohol dehydrogenase-like	2	1
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	2	1
Hypothetical protein c14orf129, hspc210	TPR-like	2	1
Myosin rod fragments	Mitotic arrest deficient-like 1, Mad1	2	2
RING/U-box	WWE domain	2	2
MIT domain	Protein kinase-like (PK-like)	2	2
FMT C-terminal domain-like	ALDH-like	2	1
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	2	2
Fibronectin type III	YWTD domain	2	1
I/LWEQ domain	alpha-catenin/vinculin-like	2	1
ARM repeat	Cysteine proteinases	2	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	2	2
TSP type-3 repeat	Concanavalin A-like lectins/glucanases	2	2
RCC1/BLIP-II	PH domain-like	2	2
A middle domain of Talin 1	alpha-catenin/vinculin-like	2	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
TrmE connector domain	P-loop containing nucleoside triphosphate hydrolases	2	2
Sec63 N-terminal domain-like	DNA/RNA polymerases	2	2
Quinoprotein alcohol dehydrogenase-like	Putative isomerase YbhE	2	2
Heme-dependent peroxidases	Ferredoxin reductase-like, C-terminal NADP-linked domain	2	1
Chaperone J-domain	RNA-binding domain, RBD	2	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	1
E set domains	Ankyrin repeat	2	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	2	1
ARM repeat	Rap/Ran-GAP	2	1
PTS-regulatory domain, PRD	Phoshotransferase/anion transport protein	2	1
Taf5 N-terminal domain-like	WD40 repeat-like	2	1
PIN domain-like	Nucleic acid-binding proteins	2	1
PX domain	Protein kinase-like (PK-like)	2	2
Carbamate kinase-like	ALDH-like	2	1
Growth factor receptor domain	SAM/Pointed domain	2	1
Cysteine-rich domain	GTPase activation domain, GAP	2	2
ARM repeat	CRAL/TRIO domain	2	2
Plexin repeat	Integrin beta tail domain	2	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	2	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	2	1
L domain-like	Actin depolymerizing proteins	2	1
TPR-like	RNA-binding domain, RBD	2	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	2	1
TPR-like	Ran binding protein zinc finger-like	2	1
BRCT domain	PH domain-like	2	2
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	2	2
WGR domain-like	ADP-ribosylation	2	1
PDZ domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Heme-dependent peroxidases	Heme-dependent peroxidases	2	1
Ubiquitin-like	PUA domain-like	2	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	2	1
Doublecortin (DC)	POZ domain	2	1
"Winged helix" DNA-binding domain	GroEL apical domain-like	2	1
PX domain	MIT domain	2	2
Immunoglobulin	YVTN repeat-like/Quinoprotein amine dehydrogenase	2	1
Doublecortin (DC)	Pentapeptide repeat-like	2	1
LDL receptor-like module	Galactose-binding domain-like	2	2
EF-hand	YVTN repeat-like/Quinoprotein amine dehydrogenase	2	1
PRTase-like	PRTase-like	2	1
DNase I-like	RNA-binding domain, RBD	2	1
Heme-dependent peroxidases	EF-hand	2	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	2	1
FAD/NAD(P)-binding domain	EF-hand	2	2
Immunoglobulin	Hormone receptor domain	2	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	2	2
E set domains	Hect, E3 ligase catalytic domain	2	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	2	1
FYVE/PHD zinc finger	PUA domain-like	2	1
FYVE/PHD zinc finger	Elongation factor TFIIS domain 2	2	2
Lipovitellin-phosvitin complex, superhelical domain	ARM repeat	2	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	2	2
Staphylococcal nuclease	Staphylococcal nuclease	2	2
DBL homology domain (DH-domain)	Quinoprotein alcohol dehydrogenase-like	2	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	2	1
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	2	2
Surp module (SWAP domain)	ENTH/VHS domain	2	1
Dcp2 domain-like	Nudix	2	1
Single hybrid motif	ClpP/crotonase	2	1
THUMP domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	2	1
DNase I-like	GTPase activation domain, GAP	2	2
Lipovitellin-phosvitin complex; beta-sheet shell regions	ARM repeat	2	1
Thiolase-like	SCP-like	2	1
SAM/Pointed domain	PH domain-like	2	2
EF-hand	Cysteine-rich domain	2	2
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	2	1
P-loop containing nucleoside triphosphate hydrolases	MOP-like	2	1
DAK1/DegV-like	DhaL-like	2	1
"Winged helix" DNA-binding domain	SAICAR synthase-like	2	1
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	2	1
Saposin	Metallo-dependent phosphatases	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	2	1
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	2	2
Phenylalanine zipper	PH domain-like	2	1
PTS system IIB component-like	Phoshotransferase/anion transport protein	2	1
TRAF domain-like	TRAF domain-like	2	2
L domain-like	Concanavalin A-like lectins/glucanases	2	2
Hormone receptor domain	Family A G protein-coupled receptor-like	2	1
Plexin repeat	Integrin domains	2	1
Zinc beta-ribbon	Cyclin-like	2	1
POZ domain	Pentapeptide repeat-like	2	1
FYVE/PHD zinc finger	GroEL apical domain-like	2	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Glucocorticoid receptor-like (DNA-binding domain)	VHP, Villin headpiece domain	2	2
Staphylococcal nuclease	Tudor/PWWP/MBT	2	2
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	2	2
Succinyl-CoA synthetase domains	Citrate synthase	2	1
Fibronectin type III	SAM/Pointed domain	2	1
GFP-like	EGF/Laminin	2	2
Tubulin nucleotide-binding domain-like	Tubulin nucleotide-binding domain-like	2	1
ARM repeat	GTPase activation domain, GAP	2	2
Putative DNA-binding domain	Cation efflux protein transmembrane domain-like	2	1
PAZ domain	dsRNA-binding domain-like	2	2
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	2
Nucleotide cyclase	P-loop containing nucleoside triphosphate hydrolases	2	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	2	2
Concanavalin A-like lectins/glucanases	BEACH domain	2	2
Galactose oxidase, central domain	Fibronectin type III	2	1
BRCA2 helical domain	Nucleic acid-binding proteins	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
Sema domain	TSP-1 type 1 repeat	2	2
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	2	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	2	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	1
Second domain of FERM	PDZ domain-like	2	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	2	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Cation efflux protein transmembrane domain-like	Cation efflux protein transmembrane domain-like	2	1
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	2	1
t-snare proteins	SNARE fusion complex	2	2
PH domain-like	I/LWEQ domain	2	1
ARM repeat	WWE domain	2	1
PX domain	Ubiquitin-like	2	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	2	1
RNI-like	Ubiquitin-like	2	1
RUN domain-like	FYVE/PHD zinc finger	2	1
Heme-dependent peroxidases	Riboflavin synthase domain-like	2	1
Ankyrin repeat	FYVE/PHD zinc finger	2	1
SH3-domain	Fibronectin type III	2	1
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	2	2
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	2	1
Formyltransferase	FMT C-terminal domain-like	2	1
GDNF receptor-like	GDNF receptor-like	2	2
Calponin-homology domain, CH-domain	GAS2 domain-like	2	1
DBL homology domain (DH-domain)	BAR/IMD domain-like	2	2
Second domain of FERM	I/LWEQ domain	2	1
L domain-like	Calponin-homology domain, CH-domain	2	1
C-type lectin-like	Fibronectin type III	2	1
NAD kinase/diacylglycerol kinase-like	SAM/Pointed domain	2	1
Phenylalanine zipper	SH2 domain	2	1
YWTD domain	Protein kinase-like (PK-like)	2	1
IP3 receptor type 1 binding core, domain 2	ARM repeat	2	1
FYVE/PHD zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	2	2
Protein kinase-like (PK-like)	L27 domain	2	1
Second domain of FERM	A middle domain of Talin 1	2	1
Ubiquitin-like	Moesin tail domain	2	1
SH3-domain	ARM repeat	2	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	2	1
PH domain-like	Bet v1-like	2	1
Nitrous oxide reductase, N-terminal domain	WD40 repeat-like	2	1
TSP type-3 repeat	TSP type-3 repeat	2	2
Galactose-binding domain-like	SAM/Pointed domain	2	1
TPR-like	Clavaminate synthase-like	2	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	1
Second domain of FERM	DBL homology domain (DH-domain)	2	2
PDZ domain-like	PX domain	2	1
Putative isomerase YbhE	TPR-like	2	2
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	2	2
HCP-like	Protein kinase-like (PK-like)	2	1
E set domains	RING/U-box	2	1
vWA-like	Complement control module/SCR domain	2	2
L domain-like	EGF/Laminin	2	2
PDZ domain-like	BAR/IMD domain-like	2	1
Nucleotide-diphospho-sugar transferases	IpsF-like	2	1
PX domain	BAR/IMD domain-like	2	2
Sema domain	Immunoglobulin	2	1
POZ domain	FYVE/PHD zinc finger	2	1
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	2	1
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	2	1
Zinc beta-ribbon	Zinc beta-ribbon	2	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	2	2
Mib/herc2 domain-like	RING/U-box	2	2
Calponin-homology domain, CH-domain	Glucocorticoid receptor-like (DNA-binding domain)	2	1
FAD/NAD(P)-binding domain	Glucocorticoid receptor-like (DNA-binding domain)	2	1
Plexin repeat	Immunoglobulin	2	1
RNA-binding domain, RBD	RING/U-box	2	2
WD40 repeat-like	EF-hand	2	2
PDZ domain-like	Regulator of G-protein signaling, RGS	1	1
CAPPD, an extracellular domain of amyloid beta A4 protein	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
Chaperone J-domain	CSL zinc finger	1	1
PDZ domain-like	GTPase activation domain, GAP	1	1
Single hybrid motif	NAD(P)-binding Rossmann-fold domains	1	1
E set domains	Complement control module/SCR domain	1	1
vWA-like	Growth factor receptor domain	1	1
Serine protease inhibitors	Serine protease inhibitors	1	1
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Nitric oxide (NO) synthase oxygenase domain	Flavoproteins	1	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
ARM repeat	UBA-like	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	1	1
"Winged helix" DNA-binding domain	Dimeric alpha+beta barrel	1	1
PX domain	GTPase activation domain, GAP	1	1
Methylglyoxal synthase-like	Cytidine deaminase-like	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	1	1
RNI-like	Immunoglobulin	1	1
BRK domain-like	Elongation factor TFIIS domain 2	1	1
TPR-like	Fic-like	1	1
DBL homology domain (DH-domain)	GTPase activation domain, GAP	1	1
ARM repeat	Thioesterase/thiol ester dehydrase-isomerase	1	1
C-type lectin-like	Concanavalin A-like lectins/glucanases	1	1
WD40 repeat-like	Galactose oxidase, central domain	1	1
Invertebrate chitin-binding proteins	Galactose-binding domain-like	1	1
GST C-terminal domain-like	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
SMAD/FHA domain	HAD-like	1	1
EF-hand	NAD kinase/diacylglycerol kinase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	1	1
beta-lactamase/transpeptidase-like	Ankyrin repeat	1	1
CAD & PB1 domains	PDZ domain-like	1	1
PTS system fructose IIA component-like	PTS IIb component	1	1
beta-beta-alpha zinc fingers	Nucleotide-diphospho-sugar transferases	1	1
Tudor/PWWP/MBT	DNA-binding domain	1	1
Histone-fold	Ankyrin repeat	1	1
Cysteine proteinases	UBA-like	1	1
HMG-box	HMG-box	1	1
WD40 repeat-like	SAM/Pointed domain	1	1
SH3-domain	Phosphoglycerate mutase-like	1	1
CoA-dependent acyltransferases	NAD(P)-binding Rossmann-fold domains	1	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	1	1
Dystroglycan, domain 2	Cadherin-like	1	1
Leech antihemostatic proteins	Leech antihemostatic proteins	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
C-type lectin-like	LDL receptor-like module	1	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	1	1
PH domain-like	HMG-box	1	1
Elafin-like	Elafin-like	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
PH domain-like	FYVE/PHD zinc finger	1	1
PLP-dependent transferases	Adenine nucleotide alpha hydrolases-like	1	1
HesB-like domain	HesB-like domain	1	1
PDZ domain-like	Cysteine-rich domain	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
C-type lectin-like	Growth factor receptor domain	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
Cadherin-like	Protein kinase-like (PK-like)	1	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Cystatin/monellin	Cysteine proteinases	1	1
Ras GEF	EF-hand	1	1
Serine protease inhibitors	Galactose-binding domain-like	1	1
Frizzled cysteine-rich domain	Trypsin-like serine proteases	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	1	1
TPR-like	Metallo-dependent phosphatases	1	1
BPTI-like	Concanavalin A-like lectins/glucanases	1	1
Homeodomain-like	Ribonuclease H-like	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Voltage-gated potassium channels	Small-conductance potassium channel	1	1
Protein kinase-like (PK-like)	KA1-like	1	1
RCC1/BLIP-II	POZ domain	1	1
Tudor/PWWP/MBT	Chromo domain-like	1	1
WW domain	PH domain-like	1	1
PurS-like	PurM N-terminal domain-like	1	1
Translation proteins	ThrRS/AlaRS common domain	1	1
F-box domain	UBC-like	1	1
beta-Roll	beta-Roll	1	1
RNI-like	Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Tudor/PWWP/MBT	1	1
RAP domain-like	RAP domain-like	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
N-acetylmuramoyl-L-alanine amidase-like	PGBD-like	1	1
SH3-domain	SAM/Pointed domain	1	1
L domain-like	PDZ domain-like	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Putative isomerase YbhE	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
SET domain	WW domain	1	1
Ada DNA repair protein, N-terminal domain (N-Ada 10)	Homeodomain-like	1	1
Thiolase-like	Thioredoxin-like	1	1
FAD-linked reductases, C-terminal domain	ThiG-like	1	1
RING/U-box	Bromodomain	1	1
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	1	1
WW domain	RING/U-box	1	1
Complement control module/SCR domain	Immunoglobulin	1	1
GST C-terminal domain-like	Methionyl-tRNA synthetase (MetRS), Zn-domain	1	1
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Apolipoprotein A-I	Apolipoprotein A-I	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
Thyroglobulin type-1 domain	Leech antihemostatic proteins	1	1
FAH	FAH	1	1
RING/U-box	P-loop containing nucleoside triphosphate hydrolases	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	YWTD domain	1	1
Ras GEF	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
SAND domain-like	HIT/MYND zinc finger-like	1	1
HRDC-like	HRDC-like	1	1
Outer arm dynein light chain 1	P-loop containing nucleoside triphosphate hydrolases	1	1
TPR-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
FYVE/PHD zinc finger	SAP domain	1	1
Ubiquitin-like	Acid proteases	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
PX domain	Outer arm dynein light chain 1	1	1
Tropomyosin	Mitotic arrest deficient-like 1, Mad1	1	1
Outer arm dynein light chain 1	Toll/Interleukin receptor TIR domain	1	1
UBA-like	Phosphoglycerate mutase-like	1	1
F-box domain	Pectin lyase-like	1	1
Homeodomain-like	Bromodomain	1	1
Regulator of G-protein signaling, RGS	PH domain-like	1	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
RNI-like	Toll/Interleukin receptor TIR domain	1	1
RING/U-box	Tropomyosin	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	LDL receptor-like module	1	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	1	1
FnI-like domain	Invertebrate chitin-binding proteins	1	1
PH domain-like	Cullin repeat-like	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
Phoshotransferase/anion transport protein	Phoshotransferase/anion transport protein	1	1
NHL repeat	WD40 repeat-like	1	1
AMMECR1-like	AMMECR1-like	1	1
Homeodomain-like	Methylated DNA-protein cysteine methyltransferase domain	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	1	1
Zinc hairpin stack	Retrovirus zinc finger-like domains	1	1
Doublecortin (DC)	Quinoprotein alcohol dehydrogenase-like	1	1
Quinoprotein alcohol dehydrogenase-like	Tricorn protease domain 2	1	1
"Winged helix" DNA-binding domain	PLP-dependent transferases	1	1
EF-hand	Ubiquitin-like	1	1
Histone-fold	POZ domain	1	1
L domain-like	Pectin lyase-like	1	1
"Winged helix" DNA-binding domain	Acyl-CoA N-acyltransferases (Nat)	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
ENTH/VHS domain	RNA-binding domain, RBD	1	1
Actin-like ATPase domain	AF1104-like	1	1
Trypsin-like serine proteases	PDZ domain-like	1	1
TPR-like	ARM repeat	1	1
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	1	1
FAD-linked reductases, C-terminal domain	MoaD/ThiS	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
RCC1/BLIP-II	VPS9 domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
ARID-like	Chromo domain-like	1	1
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	1	1
Ada DNA repair protein, N-terminal domain (N-Ada 10)	Methylated DNA-protein cysteine methyltransferase domain	1	1
PDZ domain-like	RING/U-box	1	1
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	1	1
Frizzled cysteine-rich domain	LDL receptor-like module	1	1
TrkA C-terminal domain-like	TrkA C-terminal domain-like	1	1
Cystatin/monellin	Cystatin/monellin	1	1
Ubiquitin-like	HAD-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	CCCH zinc finger	1	1
vWA-like	Concanavalin A-like lectins/glucanases	1	1
Saposin	Saposin	1	1
TPR-like	RNI-like	1	1
Pectin lyase-like	Pectin lyase-like	1	1
Leech antihemostatic proteins	BPTI-like	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
CRAL/TRIO domain	SH3-domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
F-box domain	Galactose-binding domain-like	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
beta-beta-alpha zinc fingers	FYVE/PHD zinc finger	1	1
HR1 repeat	PDZ domain-like	1	1
Ras GEF	PLC-like phosphodiesterases	1	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	1	1
14-3-3 protein	14-3-3 protein	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Folate-binding domain	TrmE connector domain	1	1
XPC-binding domain	UBA-like	1	1
Homeodomain-like	FYVE/PHD zinc finger	1	1
Eukaryotic type KH-domain (KH-domain type I)	P-loop containing nucleoside triphosphate hydrolases	1	1
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
ARM repeat	RING/U-box	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
Nitric oxide (NO) synthase oxygenase domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
SH2 domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Growth factor receptor domain	TSP type-3 repeat	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Nucleic acid-binding proteins	1	1
TPR-like	Protein prenylyltransferase	1	1
Invertebrate chitin-binding proteins	SRCR-like	1	1
SAM/Pointed domain	Toll/Interleukin receptor TIR domain	1	1
Zinc beta-ribbon	YrdC/RibB	1	1
PUG domain-like	Ubiquitin-like	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Rhodanese/Cell cycle control phosphatase	Cysteine proteinases	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
C-type lectin-like	EGF/Laminin	1	1
FYVE/PHD zinc finger	BRK domain-like	1	1
C-type lectin-like	Spermadhesin, CUB domain	1	1
Seven-hairpin glycosidases	PA domain	1	1
SMAD/FHA domain	"Winged helix" DNA-binding domain	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
Homeodomain-like	SIS domain	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
EGF/Laminin	TSP type-3 repeat	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
WW domain	EF-hand	1	1
ARM repeat	SAM/Pointed domain	1	1
YccV-like	ApaG-like	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
BRCT domain	DNA/RNA polymerases	1	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	1	1
Invertebrate chitin-binding proteins	Trypsin-like serine proteases	1	1
B-box zinc-binding domain	P-loop containing nucleoside triphosphate hydrolases	1	1
UBC-like	UBA-like	1	1
(Phosphotyrosine protein) phosphatases II	Cysteine-rich domain	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	1	1
TRAF domain-like	POZ domain	1	1
Chaperone J-domain	Chaperone J-domain	1	1
DEATH domain	Toll/Interleukin receptor TIR domain	1	1
EGF/Laminin	TIMP-like	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
Nitric oxide (NO) synthase oxygenase domain	Riboflavin synthase domain-like	1	1
Second domain of FERM	RING/U-box	1	1
TSP-1 type 1 repeat	Spermadhesin, CUB domain	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	1	1
L domain-like	Hormone receptor domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
DPP6 N-terminal domain-like	ARM repeat	1	1
Serine protease inhibitors	Invertebrate chitin-binding proteins	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
Multidrug efflux transporter AcrB transmembrane domain	Quinoprotein alcohol dehydrogenase-like	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
TROVE domain-like	vWA-like	1	1
DNA-binding domain	Homeodomain-like	1	1
VPS9 domain	Ubiquitin-like	1	1
SAM/Pointed domain	RING/U-box	1	1
SET domain	Bromodomain	1	1
B-box zinc-binding domain	Cyclophilin-like	1	1
Cysteine proteinases	Cysteine proteinases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
FnI-like domain	Galactose-binding domain-like	1	1
Bacterial hemolysins	Tropomyosin	1	1
HIT-like	HIT-like	1	1
L domain-like	PP2C-like	1	1
Transducin (alpha subunit), insertion domain	Transducin (alpha subunit), insertion domain	1	1
RNA-binding domain, RBD	Tricorn protease domain 2	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ATP-dependent DNA ligase DNA-binding domain	1	1
UBA-like	SH3-domain	1	1
GTPase activation domain, GAP	Ubiquitin-like	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
ARM repeat	Toll/Interleukin receptor TIR domain	1	1
Ubiquitin-like	Cap-Gly domain	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Quinoprotein alcohol dehydrogenase-like	F-box domain	1	1
Thioredoxin-like	TPR-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SET domain	1	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
PurS-like	PurM C-terminal domain-like	1	1
RING/U-box	UBA-like	1	1
POZ domain	Galactose-binding domain-like	1	1
PKD domain	PKD domain	1	1
Thyroglobulin type-1 domain	BPTI-like	1	1
PH domain-like	RING/U-box	1	1
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	1	1
Regulator of G-protein signaling, RGS	DBL homology domain (DH-domain)	1	1
FYVE/PHD zinc finger	PDZ domain-like	1	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	1	1
Cap-Gly domain	Cysteine proteinases	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
WWE domain	WWE domain	1	1
Pseudouridine synthase	(Phosphotyrosine protein) phosphatases II	1	1
FKBP-like	EF-hand	1	1
Tricorn protease domain 2	EF-hand	1	1
Rap/Ran-GAP	PDZ domain-like	1	1
MoaD/ThiS	ThiG-like	1	1
WD40 repeat-like	Tricorn protease domain 2	1	1
His-Me finger endonucleases	His-Me finger endonucleases	1	1
Ankyrin repeat	RNI-like	1	1
TAFH domain-like	Histone-fold	1	1
Uracil-DNA glycosylase-like	Cytidine deaminase-like	1	1
WD40 repeat-like	Bromodomain	1	1
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	1	1
P-loop containing nucleoside triphosphate hydrolases	RGC domain-like	1	1
Frizzled cysteine-rich domain	SRCR-like	1	1
Elafin-like	Fibronectin type III	1	1
L domain-like	Ubiquitin-like	1	1
PH domain-like	"Winged helix" DNA-binding domain	1	1
DNA-binding domain	SET domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1