All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
beta-beta-alpha zinc fingers | beta-beta-alpha zinc fingers | 1872 | 187 |  |
Cadherin-like | Cadherin-like | 219 | 44 |  |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 191 | 51 |  |
Ankyrin repeat | Ankyrin repeat | 164 | 23 |  |
Ankyrin repeat | DEATH domain | 150 | 11 |  |
EGF/Laminin | EGF/Laminin | 143 | 95 |  |
Immunoglobulin | Immunoglobulin | 124 | 48 |  |
RNA-binding domain, RBD | RNA-binding domain, RBD | 78 | 19 |  |
ARM repeat | ARM repeat | 68 | 27 |  |
FnI-like domain | FnI-like domain | 62 | 43 |  |
Fibronectin type III | Fibronectin type III | 61 | 32 |  |
Nicotinic receptor ligand binding domain-like | Neurotransmitter-gated ion-channel transmembrane pore | 61 | 3 |  |
Ypt/Rab-GAP domain of gyp1p | Ypt/Rab-GAP domain of gyp1p | 61 | 9 |  |
DBL homology domain (DH-domain) | PH domain-like | 59 | 16 |  |
EGF/Laminin | Growth factor receptor domain | 58 | 54 |  |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 53 | 32 |  |
TPR-like | TPR-like | 47 | 18 |  |
Actin-like ATPase domain | Actin-like ATPase domain | 47 | 11 |  |
LDL receptor-like module | LDL receptor-like module | 47 | 33 |  |
EGF/Laminin | Concanavalin A-like lectins/glucanases | 44 | 29 |  |
Immunoglobulin | Fibronectin type III | 42 | 21 |  |
Invertebrate chitin-binding proteins | Invertebrate chitin-binding proteins | 42 | 20 |  |
TSP-1 type 1 repeat | TSP-1 type 1 repeat | 41 | 32 |  |
Complement control module/SCR domain | Complement control module/SCR domain | 37 | 28 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | C2 domain (Calcium/lipid-binding domain, CaLB) | 37 | 13 |  |
Growth factor receptor domain | Growth factor receptor domain | 35 | 32 |  |
Tubulin C-terminal domain-like | Tubulin nucleotide-binding domain-like | 34 | 3 |  |
Homeodomain-like | Homeodomain-like | 33 | 12 |  |
Thioredoxin-like | GST C-terminal domain-like | 33 | 5 |  |
vWA-like | vWA-like | 32 | 13 |  |
WD40 repeat-like | WD40 repeat-like | 32 | 14 |  |
Spectrin repeat | Spectrin repeat | 31 | 27 |  |
P-loop containing nucleoside triphosphate hydrolases | SMAD/FHA domain | 30 | 8 |  |
Cysteine-rich domain | PH domain-like | 30 | 7 |  |
L domain-like | L domain-like | 30 | 16 |  |
E set domains | E set domains | 29 | 18 |  |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 28 | 9 |  |
RING/U-box | B-box zinc-binding domain | 27 | 15 |  |
(Trans)glycosidases | Chitinase insertion domain | 27 | 5 |  |
Second domain of FERM | PH domain-like | 27 | 17 |  |
Kelch motif | POZ domain | 26 | 5 |  |
EF-hand | EF-hand | 26 | 12 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Glucocorticoid receptor-like (DNA-binding domain) | 26 | 18 |  |
P-loop containing nucleoside triphosphate hydrolases | PH domain-like | 24 | 6 |  |
Eukaryotic type KH-domain (KH-domain type I) | Eukaryotic type KH-domain (KH-domain type I) | 24 | 12 |  |
SH3-domain | PH domain-like | 24 | 14 |  |
PDZ domain-like | PDZ domain-like | 23 | 15 |  |
Calcium ATPase, transmembrane domain M | Metal cation-transporting ATPase, ATP-binding domain N | 23 | 7 |  |
Calcium ATPase, transmembrane domain M | HAD-like | 23 | 7 |  |
RING/U-box | RING/U-box | 23 | 12 |  |
SAM/Pointed domain | SAM/Pointed domain | 22 | 6 |  |
Ubiquitin-like | Second domain of FERM | 22 | 16 |  |
Concanavalin A-like lectins/glucanases | LDL receptor-like module | 22 | 15 |  |
Cysteine-rich domain | DBL homology domain (DH-domain) | 22 | 2 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Nuclear receptor ligand-binding domain | 22 | 5 |  |
SH3-domain | SH3-domain | 22 | 14 |  |
ARM repeat | Protein kinase-like (PK-like) | 22 | 16 |  |
Metal cation-transporting ATPase, ATP-binding domain N | HAD-like | 22 | 6 |  |
Ankyrin repeat | SOCS box-like | 22 | 5 |  |
Hairpin loop containing domain-like | Hairpin loop containing domain-like | 21 | 13 |  |
FYVE/PHD zinc finger | FYVE/PHD zinc finger | 21 | 14 |  |
Cyclin-like | Cyclin-like | 21 | 8 |  |
EGF/Laminin | LDL receptor-like module | 20 | 13 |  |
Calponin-homology domain, CH-domain | Glucocorticoid receptor-like (DNA-binding domain) | 20 | 2 |  |
Tropomyosin | Tropomyosin | 20 | 1 |  |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 20 | 8 |  |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 19 | 7 |  |
Voltage-gated potassium channels | Voltage-gated potassium channels | 19 | 9 |  |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 19 | 10 |  |
Ubiquitin-like | PH domain-like | 19 | 14 |  |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 18 | 4 |  |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 18 | 6 |  |
PH domain-like | PH domain-like | 18 | 10 |  |
FAD/NAD(P)-binding domain | Calponin-homology domain, CH-domain | 18 | 1 |  |
FAD/NAD(P)-binding domain | Glucocorticoid receptor-like (DNA-binding domain) | 18 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 18 | 12 |  |
Sec7 domain | ARM repeat | 17 | 2 |  |
MFS general substrate transporter | Kazal-type serine protease inhibitors | 17 | 3 |  |
GroES-like | NAD(P)-binding Rossmann-fold domains | 17 | 5 |  |
EGF/Laminin | vWA-like | 16 | 14 |  |
Tudor/PWWP/MBT | Tudor/PWWP/MBT | 16 | 12 |  |
Immunoglobulin | EGF/Laminin | 16 | 10 |  |
SMAD/FHA domain | PH domain-like | 16 | 2 |  |
WW domain | WW domain | 15 | 10 |  |
Nucleotide-diphospho-sugar transferases | Ricin B-like lectins | 15 | 3 |  |
FYVE/PHD zinc finger | Bromodomain | 15 | 6 |  |
SRCR-like | SRCR-like | 15 | 11 |  |
RNI-like | F-box domain | 15 | 6 |  |
Calcium ATPase, transduction domain A | HAD-like | 15 | 5 |  |
Spectrin repeat | EF-hand | 14 | 13 |  |
Calcium ATPase, transduction domain A | Metal cation-transporting ATPase, ATP-binding domain N | 14 | 4 |  |
Kelch motif | Kelch motif | 14 | 6 |  |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 14 | 8 |  |
P-loop containing nucleoside triphosphate hydrolases | SH3-domain | 14 | 8 |  |
WD40 repeat-like | Quinoprotein alcohol dehydrogenase-like | 14 | 10 |  |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 14 | 6 |  |
Serine protease inhibitors | Serine protease inhibitors | 14 | 8 |  |
Chromo domain-like | Chromo domain-like | 13 | 5 |  |
cAMP-binding domain-like | cAMP-binding domain-like | 13 | 8 |  |
(Phosphotyrosine protein) phosphatases II | PH domain-like | 13 | 7 |  |
RING/U-box | NHL repeat | 13 | 4 |  |
ARM repeat | Formin homology 2 domain (FH2 domain) | 13 | 5 |  |
TSP-1 type 1 repeat | Serine protease inhibitors | 13 | 8 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Protein kinase-like (PK-like) | 13 | 8 |  |
Toll/Interleukin receptor TIR domain | L domain-like | 13 | 8 |  |
B-box zinc-binding domain | NHL repeat | 13 | 5 |  |
PMP inhibitors | FnI-like domain | 13 | 12 |  |
(Trans)glycosidases | Glycosyl hydrolase domain | 13 | 5 |  |
BAR/IMD domain-like | SH3-domain | 13 | 9 |  |
RING/U-box | Ankyrin repeat | 13 | 7 |  |
Immunoglobulin | Concanavalin A-like lectins/glucanases | 12 | 6 |  |
Ubiquitin-like | Ubiquitin-like | 12 | 12 |  |
LDL receptor-like module | Immunoglobulin | 12 | 6 |  |
Immunoglobulin | Protein kinase-like (PK-like) | 12 | 7 |  |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex, superhelical domain | 12 | 6 |  |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 12 | 5 |  |
p53-like transcription factors | E set domains | 12 | 5 |  |
SH2 domain | Protein kinase-like (PK-like) | 12 | 6 |  |
ABC transporter transmembrane region | ABC transporter transmembrane region | 12 | 5 |  |
Clc chloride channel | CBS-domain pair | 12 | 4 |  |
EGF/Laminin | YWTD domain | 12 | 9 |  |
Chromo domain-like | P-loop containing nucleoside triphosphate hydrolases | 12 | 4 |  |
alpha-catenin/vinculin-like | alpha-catenin/vinculin-like | 12 | 7 |  |
Thioredoxin-like | Thioredoxin-like | 12 | 8 |  |
GroEL equatorial domain-like | GroEL apical domain-like | 12 | 2 |  |
"Winged helix" DNA-binding domain | RNA-binding domain, RBD | 12 | 3 |  |
RING/U-box | TRAF domain-like | 12 | 9 |  |
Concanavalin A-like lectins/glucanases | C-type lectin-like | 12 | 1 |  |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 11 | 7 |  |
(Phosphotyrosine protein) phosphatases II | (Phosphotyrosine protein) phosphatases II | 11 | 7 |  |
Cupredoxins | Cupredoxins | 11 | 8 |  |
POZ domain | Voltage-gated potassium channels | 11 | 4 |  |
MFS general substrate transporter | MFS general substrate transporter | 11 | 4 |  |
LDL receptor-like module | Trypsin-like serine proteases | 11 | 10 |  |
Fibronectin type III | Ankyrin repeat | 11 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Phosphoglycerate mutase-like | 11 | 1 |  |
CRAL/TRIO N-terminal domain | CRAL/TRIO domain | 11 | 3 |  |
F-box domain | WD40 repeat-like | 11 | 5 |  |
Inhibitor of apoptosis (IAP) repeat | Inhibitor of apoptosis (IAP) repeat | 11 | 5 |  |
Ubiquitin-like | Protein kinase-like (PK-like) | 11 | 6 |  |
GroEL-intermediate domain like | GroEL apical domain-like | 11 | 1 |  |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 11 | 3 |  |
Spermadhesin, CUB domain | Spermadhesin, CUB domain | 11 | 10 |  |
HMG-box | HMG-box | 11 | 4 |  |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 11 | 3 |  |
FYVE/PHD zinc finger | SET domain | 11 | 4 |  |
GroEL equatorial domain-like | GroEL-intermediate domain like | 11 | 1 |  |
Nucleotide cyclase | Protein kinase-like (PK-like) | 11 | 9 |  |
Growth factor receptor domain | Concanavalin A-like lectins/glucanases | 11 | 8 |  |
P-loop containing nucleoside triphosphate hydrolases | FYVE/PHD zinc finger | 11 | 5 |  |
PH domain-like | Ypt/Rab-GAP domain of gyp1p | 11 | 3 |  |
ARM repeat | WD40 repeat-like | 10 | 6 |  |
Thiolase-like | Thiolase-like | 10 | 3 |  |
PDZ domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 10 | 2 |  |
FYVE/PHD zinc finger | RING/U-box | 10 | 4 |  |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 10 | 5 |  |
Composite domain of metallo-dependent hydrolases | Metallo-dependent hydrolases | 10 | 4 |  |
RCC1/BLIP-II | Hect, E3 ligase catalytic domain | 10 | 4 |  |
BRCT domain | BRCT domain | 10 | 8 |  |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 10 | 4 |  |
SH3-domain | SH2 domain | 10 | 9 |  |
PH domain-like | GTPase activation domain, GAP | 10 | 5 |  |
SNARE-like | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 10 | 1 |  |
BEACH domain | WD40 repeat-like | 10 | 6 |  |
Cysteine-rich domain | Cysteine-rich domain | 10 | 7 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 10 | 7 |  |
Bromodomain | Bromodomain | 10 | 4 |  |
RING/U-box | E set domains | 10 | 3 |  |
PreATP-grasp domain | Rudiment single hybrid motif | 10 | 5 |  |
PDZ domain-like | PH domain-like | 10 | 6 |  |
ENTH/VHS domain | GAT-like domain | 10 | 2 |  |
DBL homology domain (DH-domain) | SH3-domain | 10 | 6 |  |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 10 | 8 |  |
Spectrin repeat | GAS2 domain-like | 9 | 8 |  |
Actin depolymerizing proteins | Actin depolymerizing proteins | 9 | 6 |  |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 9 | 5 |  |
(Trans)glycosidases | Invertebrate chitin-binding proteins | 9 | 4 |  |
vWA-like | Growth factor receptor domain | 9 | 8 |  |
PH domain-like | ArfGap/RecO-like zinc finger | 9 | 3 |  |
Ubiquitin-like | UBA-like | 9 | 4 |  |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 9 | 2 |  |
Serine protease inhibitors | FnI-like domain | 9 | 6 |  |
Tudor/PWWP/MBT | ARID-like | 9 | 2 |  |
Ankyrin repeat | P-loop containing nucleoside triphosphate hydrolases | 9 | 7 |  |
EF-hand | GAS2 domain-like | 9 | 8 |  |
Cysteine proteinases | Calpain large subunit, middle domain (domain III) | 9 | 6 |  |
ARM repeat | Clathrin adaptor appendage domain | 9 | 3 |  |
HIT/MYND zinc finger-like | HIT/MYND zinc finger-like | 9 | 9 |  |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 9 | 5 |  |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 8 | 3 |  |
EGF/Laminin | Fibronectin type III | 8 | 1 |  |
LDL receptor-like module | YWTD domain | 8 | 7 |  |
Voltage-gated potassium channels | cAMP-binding domain-like | 8 | 5 |  |
Cysteine-rich domain | Protein kinase-like (PK-like) | 8 | 4 |  |
Spermadhesin, CUB domain | EGF/Laminin | 8 | 7 |  |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 8 | 5 |  |
dsRNA-binding domain-like | dsRNA-binding domain-like | 8 | 6 |  |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 8 | 4 |  |
CalX-like | CalX-like | 8 | 5 |  |
Calponin-homology domain, CH-domain | E set domains | 8 | 4 |  |
Metalloproteases ("zincins"), catalytic domain | TSP-1 type 1 repeat | 8 | 8 |  |
Regulator of G-protein signaling, RGS | Cysteine-rich domain | 8 | 1 |  |
RCC1/BLIP-II | Galactose-binding domain-like | 8 | 2 |  |
Tudor/PWWP/MBT | FYVE/PHD zinc finger | 8 | 5 |  |
PH domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 8 | 6 |  |
GAF domain-like | GAF domain-like | 8 | 3 |  |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 8 | 4 |  |
ArfGap/RecO-like zinc finger | Ankyrin repeat | 8 | 5 |  |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 8 | 3 |  |
GAF domain-like | HD-domain/PDEase-like | 8 | 4 |  |
RCC1/BLIP-II | RING/U-box | 8 | 2 |  |
Transducin (alpha subunit), insertion domain | P-loop containing nucleoside triphosphate hydrolases | 8 | 3 |  |
FAS1 domain | FAS1 domain | 8 | 4 |  |
lambda repressor-like DNA-binding domains | Homeodomain-like | 8 | 2 |  |
RING/U-box | Galactose-binding domain-like | 8 | 2 |  |
Regulator of G-protein signaling, RGS | PH domain-like | 8 | 1 |  |
EF-hand | RING/U-box | 8 | 6 |  |
Chitinase insertion domain | Invertebrate chitin-binding proteins | 8 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 8 | 4 |  |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 8 | 4 |  |
EGF/Laminin | Complement control module/SCR domain | 8 | 7 |  |
RCC1/BLIP-II | RCC1/BLIP-II | 8 | 4 |  |
Regulator of G-protein signaling, RGS | DBL homology domain (DH-domain) | 8 | 1 |  |
Rudiment single hybrid motif | Single hybrid motif | 8 | 4 |  |
PreATP-grasp domain | Single hybrid motif | 8 | 4 |  |
Voltage-gated potassium channels | E set domains | 7 | 2 |  |
Ankyrin repeat | SH3-domain | 7 | 4 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | GTPase activation domain, GAP | 7 | 4 |  |
TPR-like | HIT/MYND zinc finger-like | 7 | 4 |  |
Purple acid phosphatase, N-terminal domain | Metallo-dependent phosphatases | 7 | 3 |  |
PMP inhibitors | PMP inhibitors | 7 | 6 |  |
PDZ domain-like | SH3-domain | 7 | 5 |  |
Intermediate filament protein, coiled coil region | Myosin rod fragments | 7 | 6 |  |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 7 | 3 |  |
Cysteine-rich domain | NAD kinase/diacylglycerol kinase-like | 7 | 5 |  |
P-loop containing nucleoside triphosphate hydrolases | Protein kinase-like (PK-like) | 7 | 3 |  |
FYVE/PHD zinc finger | Chromo domain-like | 7 | 2 |  |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 7 | 2 |  |
HMG-box | FYVE/PHD zinc finger | 7 | 2 |  |
HMG-box | Chromo domain-like | 7 | 2 |  |
BAR/IMD domain-like | PH domain-like | 7 | 4 |  |
Clathrin adaptor appendage domain | Subdomain of clathrin and coatomer appendage domain | 7 | 2 |  |
Cullin homology domain | "Winged helix" DNA-binding domain | 7 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 7 | 5 |  |
Ankyrin repeat | SAM/Pointed domain | 7 | 7 |  |
ClpP/crotonase | ClpP/crotonase | 7 | 3 |  |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 7 | 4 |  |
ARM repeat | Subdomain of clathrin and coatomer appendage domain | 7 | 2 |  |
LDL receptor-like module | Spermadhesin, CUB domain | 7 | 7 |  |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 7 | 4 |  |
Myosin rod fragments | Myosin rod fragments | 7 | 4 |  |
Calponin-homology domain, CH-domain | Spectrin repeat | 7 | 5 |  |
YWTD domain | YWTD domain | 7 | 7 |  |
Metalloproteases ("zincins"), catalytic domain | Concanavalin A-like lectins/glucanases | 7 | 2 |  |
Concanavalin A-like lectins/glucanases | WD40 repeat-like | 7 | 2 |  |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 7 | 4 |  |
p53-like transcription factors | DNA-binding protein LAG-1 (CSL) | 7 | 2 |  |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 7 | 1 |  |
PHM/PNGase F | PHM/PNGase F | 7 | 4 |  |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 7 | 6 |  |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 7 | 5 |  |
HMG-box | P-loop containing nucleoside triphosphate hydrolases | 7 | 2 |  |
Voltage-gated potassium channels | Periplasmic binding protein-like II | 7 | 6 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Homeodomain-like | 7 | 6 |  |
Fibronectin type III | Protein kinase-like (PK-like) | 7 | 7 |  |
RING/U-box | Cysteine proteinases | 7 | 7 |  |
Complement control module/SCR domain | Hairpin loop containing domain-like | 7 | 7 |  |
DNA-binding protein LAG-1 (CSL) | E set domains | 7 | 2 |  |
Plakin repeat | Plakin repeat | 7 | 6 |  |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 7 | 5 |  |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 7 | 5 |  |
Spermadhesin, CUB domain | Complement control module/SCR domain | 7 | 5 |  |
PLC-like phosphodiesterases | C2 domain (Calcium/lipid-binding domain, CaLB) | 6 | 6 |  |
"Winged helix" DNA-binding domain | E2F-DP heterodimerization region | 6 | 2 |  |
PH domain-like | alpha-catenin/vinculin-like | 6 | 1 |  |
Periplasmic binding protein-like I | Periplasmic binding protein-like II | 6 | 5 |  |
DEATH domain | Caspase-like | 6 | 2 |  |
Class I glutamine amidotransferase-like | Methylglyoxal synthase-like | 6 | 3 |  |
Ubiquitin-like | RING/U-box | 6 | 4 |  |
RCC1/BLIP-II | E set domains | 6 | 1 |  |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 6 | 4 |  |
Class I glutamine amidotransferase-like | Glutathione synthetase ATP-binding domain-like | 6 | 3 |  |
EF-hand | Cysteine proteinases | 6 | 4 |  |
Ubiquitin-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 6 | 4 |  |
Subtilisin-like | Galactose-binding domain-like | 6 | 5 |  |
PH domain-like | BEACH domain | 6 | 3 |  |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 6 | 3 |  |
Class I glutamine amidotransferase-like | PreATP-grasp domain | 6 | 3 |  |
Kringle-like | Protein kinase-like (PK-like) | 6 | 2 |  |
Cysteine-rich domain | GTPase activation domain, GAP | 6 | 4 |  |
RNA-binding domain, RBD | Ran binding protein zinc finger-like | 6 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 6 | 4 |  |
SAM/Pointed domain | PH domain-like | 6 | 3 |  |
Cullin repeat-like | Cullin homology domain | 6 | 3 |  |
Metalloproteases ("zincins"), catalytic domain | Hemopexin-like domain | 6 | 5 |  |
TSP-1 type 1 repeat | FnI-like domain | 6 | 3 |  |
Glycoside hydrolase/deacetylase | Galactose mutarotase-like | 6 | 4 |  |
Tudor/PWWP/MBT | HMG-box | 6 | 1 |  |
A middle domain of Talin 1 | I/LWEQ domain | 6 | 1 |  |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 6 | 4 |  |
SH2 domain | PH domain-like | 6 | 5 |  |
Families 57/38 glycoside transferase middle domain | Galactose mutarotase-like | 6 | 4 |  |
Glutathione synthetase ATP-binding domain-like | Carbamoyl phosphate synthetase, large subunit connection domain | 6 | 3 |  |
EF-hand | Cysteine-rich domain | 6 | 2 |  |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 6 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 6 | 2 |  |
Second domain of FERM | A middle domain of Talin 1 | 6 | 1 |  |
PDZ domain-like | P-loop containing nucleoside triphosphate hydrolases | 6 | 4 |  |
Terpenoid cyclases/Protein prenyltransferases | Alpha-macroglobulin receptor domain | 6 | 3 |  |
RNI-like | EF-hand | 6 | 2 |  |
TSP-1 type 1 repeat | Immunoglobulin | 6 | 6 |  |
Second domain of FERM | I/LWEQ domain | 6 | 1 |  |
Ankyrin repeat | Protein kinase-like (PK-like) | 6 | 5 |  |
A middle domain of Talin 1 | alpha-catenin/vinculin-like | 6 | 1 |  |
HIT/MYND zinc finger-like | SET domain | 6 | 3 |  |
LDL receptor-like module | SRCR-like | 6 | 6 |  |
PH domain-like | Ankyrin repeat | 6 | 3 |  |
Spectrin repeat | PH domain-like | 6 | 3 |  |
PH domain-like | WD40 repeat-like | 6 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | WD40 repeat-like | 6 | 2 |  |
PreATP-grasp domain | Carbamoyl phosphate synthetase, large subunit connection domain | 6 | 3 |  |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 6 | 3 |  |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 6 | 3 |  |
PH domain-like | Protein kinase-like (PK-like) | 6 | 5 |  |
Class I glutamine amidotransferase-like | Carbamoyl phosphate synthetase, large subunit connection domain | 6 | 3 |  |
FF domain | FF domain | 6 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Sec63 N-terminal domain-like | 6 | 5 |  |
P-loop containing nucleoside triphosphate hydrolases | Bromodomain | 6 | 2 |  |
PH domain-like | I/LWEQ domain | 6 | 1 |  |
L domain-like | Growth factor receptor domain | 6 | 5 |  |
EF-hand | PLC-like phosphodiesterases | 6 | 5 |  |
I/LWEQ domain | alpha-catenin/vinculin-like | 6 | 1 |  |
ARM repeat | Ankyrin repeat | 6 | 4 |  |
Rhodanese/Cell cycle control phosphatase | (Phosphotyrosine protein) phosphatases II | 6 | 3 |  |
Family A G protein-coupled receptor-like | Family A G protein-coupled receptor-like | 6 | 6 |  |
HIT/MYND zinc finger-like | Tudor/PWWP/MBT | 6 | 2 |  |
Concanavalin A-like lectins/glucanases | ARM repeat | 6 | 2 |  |
L domain-like | Immunoglobulin | 6 | 4 |  |
Galactose-binding domain-like | Hect, E3 ligase catalytic domain | 6 | 4 |  |
L domain-like | Family A G protein-coupled receptor-like | 6 | 4 |  |
Inosine monophosphate dehydrogenase (IMPDH) | Inosine monophosphate dehydrogenase (IMPDH) | 6 | 2 |  |
PP2C-like | Protein serine/threonine phosphatase 2C, C-terminal domain | 6 | 1 |  |
Frizzled cysteine-rich domain | Frizzled cysteine-rich domain | 6 | 3 |  |
WD40 repeat-like | TPR-like | 6 | 4 |  |
SRCR-like | Trypsin-like serine proteases | 6 | 6 |  |
Kringle-like | Kringle-like | 6 | 2 |  |
Translation proteins | EF-G C-terminal domain-like | 6 | 4 |  |
Intermediate filament protein, coiled coil region | Lamin A/C globular tail domain | 6 | 4 |  |
WW domain | FF domain | 6 | 2 |  |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 6 | 3 |  |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 6 | 2 |  |
E set domains | Galactose-binding domain-like | 6 | 1 |  |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipoxigenase | 6 | 1 |  |
PH domain-like | A middle domain of Talin 1 | 6 | 1 |  |
Second domain of FERM | alpha-catenin/vinculin-like | 6 | 1 |  |
Spectrin repeat | Plakin repeat | 6 | 5 |  |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 6 | 4 |  |
PreATP-grasp domain | PreATP-grasp domain | 6 | 3 |  |
PX domain | Protein kinase-like (PK-like) | 6 | 5 |  |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 6 | 3 |  |
PreATP-grasp domain | Methylglyoxal synthase-like | 6 | 3 |  |
Kazal-type serine protease inhibitors | Kazal-type serine protease inhibitors | 5 | 4 |  |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 5 | 2 |  |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | Zinc-binding domain of translation initiation factor 2 beta | 5 | 2 |  |
L domain-like | P-loop containing nucleoside triphosphate hydrolases | 5 | 4 |  |
Bromodomain | Tudor/PWWP/MBT | 5 | 2 |  |
Ran binding protein zinc finger-like | RING/U-box | 5 | 3 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Methylglyoxal synthase-like | 5 | 2 |  |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 5 | 3 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Carbamoyl phosphate synthetase, large subunit connection domain | 5 | 2 |  |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 5 | 5 |  |
Periplasmic binding protein-like I | Periplasmic binding protein-like I | 5 | 4 |  |
Glucocorticoid receptor-like (DNA-binding domain) | POZ domain | 5 | 3 |  |
ARM repeat | PH domain-like | 5 | 2 |  |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 5 | 2 |  |
EGF/Laminin | Invertebrate chitin-binding proteins | 5 | 5 |  |
Zn-finger domain of Sec23/24 | Helical domain of Sec23/24 | 5 | 2 |  |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 5 | 2 |  |
Plakin repeat | GAS2 domain-like | 5 | 4 |  |
Di-copper centre-containing domain | C-terminal domain of mollusc hemocyanin | 5 | 5 |  |
Mib/herc2 domain-like | Hect, E3 ligase catalytic domain | 5 | 3 |  |
ARM repeat | TPR-like | 5 | 5 |  |
Translation proteins | Ribosomal protein S5 domain 2-like | 5 | 3 |  |
BAR/IMD domain-like | Ankyrin repeat | 5 | 2 |  |
Single hybrid motif | CoA-dependent acyltransferases | 5 | 5 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Glutathione synthetase ATP-binding domain-like | 5 | 2 |  |
NHL repeat | Soluble quinoprotein glucose dehydrogenase | 5 | 2 |  |
Ran binding protein zinc finger-like | Ran binding protein zinc finger-like | 5 | 3 |  |
Calpain large subunit, middle domain (domain III) | EF-hand | 5 | 3 |  |
Flavoproteins | Riboflavin synthase domain-like | 5 | 3 |  |
beta-sandwich domain of Sec23/24 | Helical domain of Sec23/24 | 5 | 2 |  |
Integrin alpha N-terminal domain | Integrin domains | 5 | 4 |  |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 5 | 2 |  |
Sema domain | Plexin repeat | 5 | 5 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 5 | 2 |  |
RING/U-box | Homeodomain-like | 5 | 4 |  |
Nucleotide-binding domain | FAD-linked reductases, C-terminal domain | 5 | 1 |  |
Fibronectin type III | (Phosphotyrosine protein) phosphatases II | 5 | 5 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | ARM repeat | 5 | 4 |  |
L27 domain | PDZ domain-like | 5 | 3 |  |
PH domain-like | Oxysterol-binding protein-like | 5 | 3 |  |
Plakin repeat | EF-hand | 5 | 4 |  |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 5 | 1 |  |
SH3-domain | Protein kinase-like (PK-like) | 5 | 5 |  |
PDZ domain-like | DBL homology domain (DH-domain) | 5 | 3 |  |
PKD domain | PKD domain | 5 | 5 |  |
PurM N-terminal domain-like | PurM C-terminal domain-like | 5 | 3 |  |
Ribonuclease H-like | DNA/RNA polymerases | 5 | 5 |  |
GST C-terminal domain-like | Nucleotidylyl transferase | 5 | 3 |  |
FKBP-like | TPR-like | 5 | 3 |  |
Intermediate filament protein, coiled coil region | Intermediate filament protein, coiled coil region | 5 | 4 |  |
GTPase activation domain, GAP | ARM repeat | 5 | 1 |  |
Protein kinase-like (PK-like) | Protein kinase-like (PK-like) | 5 | 3 |  |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 5 | 3 |  |
Metalloproteases ("zincins"), catalytic domain | Blood coagulation inhibitor (disintegrin) | 5 | 2 |  |
SAM/Pointed domain | GTPase activation domain, GAP | 5 | 2 |  |
PGBD-like | Metalloproteases ("zincins"), catalytic domain | 5 | 4 |  |
vWA-like | Helical domain of Sec23/24 | 5 | 2 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | PreATP-grasp domain | 5 | 2 |  |
BRK domain-like | P-loop containing nucleoside triphosphate hydrolases | 5 | 2 |  |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 5 | 3 |  |
Retrovirus zinc finger-like domains | Retrovirus zinc finger-like domains | 5 | 2 |  |
Zn-finger domain of Sec23/24 | vWA-like | 5 | 2 |  |
S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 5 | 4 |  |
RNA-binding domain, RBD | S-adenosyl-L-methionine-dependent methyltransferases | 5 | 2 |  |
ARM repeat | "Winged helix" DNA-binding domain | 5 | 2 |  |
Doublecortin (DC) | Doublecortin (DC) | 5 | 4 |  |
SNARE-like | SNARE fusion complex | 5 | 2 |  |
EF-hand | Eferin C-derminal domain-like | 5 | 1 |  |
Second domain of FERM | Second domain of FERM | 5 | 5 |  |
Cullin repeat-like | "Winged helix" DNA-binding domain | 5 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Smc hinge domain | 5 | 5 |  |
L domain-like | Protein kinase-like (PK-like) | 5 | 4 |  |
ArfGap/RecO-like zinc finger | SH3-domain | 5 | 2 |  |
Mib/herc2 domain-like | Galactose-binding domain-like | 5 | 3 |  |
TPR-like | SET domain | 5 | 2 |  |
DEATH domain | DEATH domain | 5 | 1 |  |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex; beta-sheet shell regions | 5 | 3 |  |
Periplasmic binding protein-like I | Voltage-gated potassium channels | 5 | 4 |  |
Integrin domains | Integrin domains | 5 | 4 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | vWA-like | 5 | 3 |  |
Leukotriene A4 hydrolase N-terminal domain | Metalloproteases ("zincins"), catalytic domain | 5 | 3 |  |
POZ domain | POZ domain | 5 | 5 |  |
ARM repeat | Cysteine proteinases | 5 | 3 |  |
GST C-terminal domain-like | S15/NS1 RNA-binding domain | 5 | 3 |  |
Tudor/PWWP/MBT | SAM/Pointed domain | 5 | 3 |  |
BPTI-like | BPTI-like | 5 | 4 |  |
Flavoproteins | Ferredoxin reductase-like, C-terminal NADP-linked domain | 5 | 3 |  |
SH2 domain | SOCS box-like | 5 | 2 |  |
beta-sandwich domain of Sec23/24 | vWA-like | 5 | 2 |  |
BAR/IMD domain-like | ArfGap/RecO-like zinc finger | 5 | 2 |  |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 5 | 2 |  |
Nucleotidylyl transferase | S15/NS1 RNA-binding domain | 5 | 3 |  |
SH3-domain | RUN domain-like | 5 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Concanavalin A-like lectins/glucanases | 5 | 4 |  |
WW domain | Hect, E3 ligase catalytic domain | 5 | 5 |  |
Periplasmic binding protein-like I | Protein kinase-like (PK-like) | 5 | 5 |  |
SAM/Pointed domain | "Winged helix" DNA-binding domain | 5 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 5 | 3 |  |
beta-sandwich domain of Sec23/24 | Zn-finger domain of Sec23/24 | 5 | 2 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
vWA-like | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 1 |  |
Spectrin repeat | SH3-domain | 4 | 4 |  |
Zn-finger domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 1 |  |
SET domain | beta-beta-alpha zinc fingers | 4 | 3 |  |
Myosin rod fragments | Lamin A/C globular tail domain | 4 | 3 |  |
TGS-like | ThrRS/AlaRS common domain | 4 | 3 |  |
SEA domain | Frizzled cysteine-rich domain | 4 | 2 |  |
POZ domain | beta-beta-alpha zinc fingers | 4 | 4 |  |
Ankyrin repeat | L domain-like | 4 | 3 |  |
SH2 domain | SH2 domain | 4 | 4 |  |
TPR-like | Protein kinase-like (PK-like) | 4 | 4 |  |
C-terminal domain of mollusc hemocyanin | C-terminal domain of mollusc hemocyanin | 4 | 4 |  |
Sec7 domain | PH domain-like | 4 | 3 |  |
Carbamoyl phosphate synthetase, large subunit connection domain | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
Single hybrid motif | ClpP/crotonase | 4 | 1 |  |
Carbamoyl phosphate synthetase, large subunit connection domain | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
Clavaminate synthase-like | S-adenosyl-L-methionine-dependent methyltransferases | 4 | 1 |  |
ArfGap/RecO-like zinc finger | GTPase activation domain, GAP | 4 | 1 |  |
Concanavalin A-like lectins/glucanases | PH domain-like | 4 | 1 |  |
PreATP-grasp domain | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
Class I glutamine amidotransferase-like | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
USP8 N-terminal domain-like | JAB1/MPN domain | 4 | 1 |  |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 4 | 3 |  |
RNA-binding domain, RBD | Tudor/PWWP/MBT | 4 | 3 |  |
ATP-dependent DNA ligase DNA-binding domain | DNA ligase/mRNA capping enzyme, catalytic domain | 4 | 4 |  |
Mannose 6-phosphate receptor domain | Mannose 6-phosphate receptor domain | 4 | 4 |  |
ARM repeat | BEACH domain | 4 | 1 |  |
SET domain | Bromodomain | 4 | 1 |  |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 4 | 4 |  |
MAST3 pre-PK domain-like | PDZ domain-like | 4 | 1 |  |
Composite domain of metallo-dependent hydrolases | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
MAST3 pre-PK domain-like | Protein kinase-like (PK-like) | 4 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | TPR-like | 4 | 4 |  |
Domain of poly(ADP-ribose) polymerase | ADP-ribosylation | 4 | 4 |  |
PDZ domain-like | SAM/Pointed domain | 4 | 4 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 4 | 2 |  |
Succinyl-CoA synthetase domains | Citrate synthase | 4 | 1 |  |
Class I glutamine amidotransferase-like | Metallo-dependent hydrolases | 4 | 1 |  |
PH domain-like | FYVE/PHD zinc finger | 4 | 4 |  |
C-type lectin-like | C-type lectin-like | 4 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 4 | 2 |  |
BAR/IMD domain-like | GTPase activation domain, GAP | 4 | 4 |  |
Bromodomain | HIT/MYND zinc finger-like | 4 | 1 |  |
FLJ32549 domain-like | FLJ32549 C-terminal domain-like | 4 | 1 |  |
E set domains | NHL repeat | 4 | 2 |  |
Hormone receptor domain | Family A G protein-coupled receptor-like | 4 | 3 |  |
"Winged helix" DNA-binding domain | Sec63 N-terminal domain-like | 4 | 3 |  |
Zn-dependent exopeptidases | Carboxypeptidase regulatory domain-like | 4 | 3 |  |
Helical domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 1 |  |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 4 | 4 |  |
Retrovirus zinc finger-like domains | P-loop containing nucleoside triphosphate hydrolases | 4 | 3 |  |
Glutathione synthetase ATP-binding domain-like | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
C-type lectin-like | Hairpin loop containing domain-like | 4 | 3 |  |
PABC (PABP) domain | Hect, E3 ligase catalytic domain | 4 | 1 |  |
Metallo-dependent hydrolases | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
Fumarylacetoacetate hydrolase, FAH, N-terminal domain | FAH | 4 | 1 |  |
Ankyrin repeat | Eukaryotic type KH-domain (KH-domain type I) | 4 | 1 |  |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | ARM repeat | 4 | 1 |  |
beta-beta-alpha zinc fingers | Homeodomain-like | 4 | 4 |  |
Zinc-binding domain of translation initiation factor 2 beta | ARM repeat | 4 | 1 |  |
EGF/Laminin | Integrin beta tail domain | 4 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | PX domain | 4 | 1 |  |
Galactose mutarotase-like | (Trans)glycosidases | 4 | 2 |  |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 4 | 3 |  |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 4 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 1 |  |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 4 | 3 |  |
Carboxypeptidase regulatory domain-like | NHL repeat | 4 | 1 |  |
Ras GEF | PH domain-like | 4 | 3 |  |
Glutathione synthetase ATP-binding domain-like | Metallo-dependent hydrolases | 4 | 1 |  |
ATP-dependent DNA ligase DNA-binding domain | Nucleic acid-binding proteins | 4 | 4 |  |
Phospholipase D/nuclease | Phospholipase D/nuclease | 4 | 3 |  |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 4 | 2 |  |
Thioredoxin-like | Ubiquitin-like | 4 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
Plexin repeat | E set domains | 4 | 4 |  |
E set domains | Transglutaminase, two C-terminal domains | 4 | 3 |  |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | S15/NS1 RNA-binding domain | 4 | 2 |  |
HLH, helix-loop-helix DNA-binding domain | PYP-like sensor domain (PAS domain) | 4 | 3 |  |
Methylglyoxal synthase-like | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
RING/U-box | Mib/herc2 domain-like | 4 | 2 |  |
RCC1/BLIP-II | PABC (PABP) domain | 4 | 1 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Metallo-dependent hydrolases | 4 | 1 |  |
Class I glutamine amidotransferase-like | Aspartate/ornithine carbamoyltransferase | 4 | 1 |  |
HSP20-like chaperones | HSP20-like chaperones | 4 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Citrate synthase | 4 | 1 |  |
B-box zinc-binding domain | E set domains | 4 | 2 |  |
(Phosphotyrosine protein) phosphatases II | Cysteine-rich domain | 4 | 2 |  |
Concanavalin A-like lectins/glucanases | BEACH domain | 4 | 1 |  |
WW domain | RING/U-box | 4 | 3 |  |
Concanavalin A-like lectins/glucanases | Trypsin-like serine proteases | 4 | 4 |  |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 4 | 1 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleotidylyl transferase | 4 | 2 |  |
SMAD/FHA domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 1 |  |
Cysteine proteinases | Cysteine proteinases | 4 | 4 |  |
Ypt/Rab-GAP domain of gyp1p | SH3-domain | 4 | 1 |  |
SAM/Pointed domain | ArfGap/RecO-like zinc finger | 4 | 1 |  |
E set domains | Ankyrin repeat | 4 | 2 |  |
PreATP-grasp domain | Metallo-dependent hydrolases | 4 | 1 |  |
PH domain-like | EF-hand | 4 | 3 |  |
tRNA-binding arm | Class II aaRS and biotin synthetases | 4 | 3 |  |
Acid proteases | DNA/RNA polymerases | 4 | 2 |  |
Periplasmic binding protein-like I | Nucleotide cyclase | 4 | 4 |  |
SAM/Pointed domain | SH2 domain | 4 | 3 |  |
POZ domain | Galactose oxidase, central domain | 4 | 3 |  |
Di-copper centre-containing domain | Di-copper centre-containing domain | 4 | 4 |  |
Ubiquitin-like | Ras GEF | 4 | 3 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | S15/NS1 RNA-binding domain | 4 | 2 |  |
SMAD/FHA domain | PX domain | 4 | 1 |  |
E set domains | Cysteine proteinases | 4 | 3 |  |
beta-sandwich domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 4 | 1 |  |
Ras GEF | EF-hand | 4 | 1 |  |
Ubiquitin-like | Ran binding protein zinc finger-like | 4 | 2 |  |
Ribosomal L27 protein-like | Nucleic acid-binding proteins | 4 | 2 |  |
Spermadhesin, CUB domain | Growth factor receptor domain | 4 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | E set domains | 4 | 2 |  |
Metalloproteases ("zincins"), catalytic domain | Spermadhesin, CUB domain | 4 | 2 |  |
BRK domain-like | Bromodomain | 4 | 1 |  |
RNA-binding domain, RBD | Retrovirus zinc finger-like domains | 4 | 2 |  |
Carbamoyl phosphate synthetase, large subunit connection domain | Metallo-dependent hydrolases | 4 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Citrate synthase | 4 | 1 |  |
Ypt/Rab-GAP domain of gyp1p | RUN domain-like | 4 | 1 |  |
RNA-binding domain, RBD | Clavaminate synthase-like | 4 | 1 |  |
CRAL/TRIO domain | Supernatant protein factor (SPF), C-terminal domain | 4 | 2 |  |
C-type lectin-like | LDL receptor-like module | 4 | 4 |  |
PreATP-grasp domain | ClpP/crotonase | 4 | 1 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 4 | 2 |  |
Ankyrin repeat | alpha-catenin/vinculin-like | 4 | 1 |  |
Rudiment single hybrid motif | ClpP/crotonase | 4 | 1 |  |
dsRNA-binding domain-like | P-loop containing nucleoside triphosphate hydrolases | 4 | 2 |  |
ARM repeat | alpha/beta-Hydrolases | 4 | 2 |  |
ACP-like | NAD(P)-binding Rossmann-fold domains | 4 | 2 |  |
Glutathione synthetase ATP-binding domain-like | NAD(P)-binding Rossmann-fold domains | 4 | 1 |  |
ARM repeat | P-loop containing nucleoside triphosphate hydrolases | 4 | 2 |  |
PH domain-like | PLC-like phosphodiesterases | 4 | 3 |  |
GST C-terminal domain-like | Methionyl-tRNA synthetase (MetRS), Zn-domain | 4 | 2 |  |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 4 | 3 |  |
WD40 repeat-like | SNARE fusion complex | 4 | 2 |  |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 4 | 3 |  |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 4 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Cysteine-rich domain | 4 | 2 |  |
Protein kinase-like (PK-like) | PDZ domain-like | 4 | 1 |  |
Cryptochrome/photolyase, N-terminal domain | Cryptochrome/photolyase FAD-binding domain | 4 | 2 |  |
Carboxypeptidase regulatory domain-like | Soluble quinoprotein glucose dehydrogenase | 4 | 1 |  |
PreATP-grasp domain | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
GST C-terminal domain-like | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 4 | 2 |  |
Glutathione synthetase ATP-binding domain-like | ClpP/crotonase | 4 | 1 |  |
Sec63 N-terminal domain-like | E set domains | 4 | 3 |  |
Galactose-binding domain-like | Galactose-binding domain-like | 4 | 3 |  |
Methylglyoxal synthase-like | Metallo-dependent hydrolases | 4 | 1 |  |
Ras GEF | Cysteine-rich domain | 4 | 1 |  |
FYVE/PHD zinc finger | HIT/MYND zinc finger-like | 4 | 1 |  |
Cysteine proteinases | Transglutaminase, two C-terminal domains | 4 | 3 |  |
Protein kinase-like (PK-like) | WD40 repeat-like | 4 | 3 |  |
TAF(II)230 TBP-binding fragment | Bromodomain | 4 | 1 |  |
Methylglyoxal synthase-like | Composite domain of metallo-dependent hydrolases | 4 | 1 |  |
PAZ domain | Ribonuclease H-like | 4 | 3 |  |
WW domain | EF-hand | 4 | 3 |  |
FYVE/PHD zinc finger | Clavaminate synthase-like | 3 | 3 |  |
RING/U-box | UBA-like | 3 | 2 |  |
Nucleic acid-binding proteins | BRCT domain | 3 | 3 |  |
Transglutaminase, two C-terminal domains | Transglutaminase, two C-terminal domains | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 3 | 1 |  |
TSP-1 type 1 repeat | EGF/Laminin | 3 | 3 |  |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 3 | 1 |  |
RuvA domain 2-like | RuvA domain 2-like | 3 | 3 |  |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 3 | 2 |  |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | CBS-domain pair | 3 | 1 |  |
Flavoproteins | Radical SAM enzymes | 3 | 1 |  |
EF-hand | Mitochondrial carrier | 3 | 3 |  |
GINS helical bundle-like | PriA/YqbF domain | 3 | 2 |  |
Calponin-homology domain, CH-domain | EF-hand | 3 | 3 |  |
WGR domain-like | ADP-ribosylation | 3 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | RING/U-box | 3 | 2 |  |
SAM/Pointed domain | RING/U-box | 3 | 2 |  |
Carbohydrate-binding domain | (Trans)glycosidases | 3 | 2 |  |
Sec63 N-terminal domain-like | Sec63 N-terminal domain-like | 3 | 2 |  |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 3 | 2 |  |
PABC (PABP) domain | PABC (PABP) domain | 3 | 2 |  |
Protein kinase-like (PK-like) | RCC1/BLIP-II | 3 | 1 |  |
ARM repeat | Toll/Interleukin receptor TIR domain | 3 | 2 |  |
vWA-like | Integrin domains | 3 | 2 |  |
Homeodomain-like | FAD-linked reductases, C-terminal domain | 3 | 2 |  |
PX domain | BAR/IMD domain-like | 3 | 3 |  |
UBA-like | UBA-like | 3 | 2 |  |
PDZ domain-like | Ubiquitin-like | 3 | 2 |  |
SMAD/FHA domain | BRCT domain | 3 | 2 |  |
RCC1/BLIP-II | WD40 repeat-like | 3 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | Protein kinase-like (PK-like) | 3 | 2 |  |
Ubiquitin-like | Cysteine-rich domain | 3 | 2 |  |
Acetyl-CoA synthetase-like | ACP-like | 3 | 2 |  |
SAP domain | RNA-binding domain, RBD | 3 | 2 |  |
Heme-dependent peroxidases | TSP-1 type 1 repeat | 3 | 2 |  |
Kringle-like | Immunoglobulin | 3 | 1 |  |
FKBP-like | EF-hand | 3 | 1 |  |
Nucleoside diphosphate kinase, NDK | Nucleoside diphosphate kinase, NDK | 3 | 2 |  |
DNA polymerase beta, N-terminal domain-like | PsbU/PolX domain-like | 3 | 2 |  |
TPR-like | HCP-like | 3 | 3 |  |
Calponin-homology domain, CH-domain | EB1 dimerisation domain-like | 3 | 1 |  |
Invertebrate chitin-binding proteins | Concanavalin A-like lectins/glucanases | 3 | 3 |  |
Protein kinase-like (PK-like) | Polo-box domain | 3 | 2 |  |
Kazal-type serine protease inhibitors | Growth factor receptor domain | 3 | 2 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 3 | 3 |  |
Concanavalin A-like lectins/glucanases | Family A G protein-coupled receptor-like | 3 | 1 |  |
Activating enzymes of the ubiquitin-like proteins | Activating enzymes of the ubiquitin-like proteins | 3 | 1 |  |
SH2 domain | RING/U-box | 3 | 2 |  |
N-terminal, heterodimerisation domain of RBP7 (RpoE) | Nucleic acid-binding proteins | 3 | 1 |  |
(Phosphotyrosine protein) phosphatases II | C2 domain (Calcium/lipid-binding domain, CaLB) | 3 | 2 |  |
Second domain of FERM | SH3-domain | 3 | 3 |  |
RNI-like | L domain-like | 3 | 3 |  |
RNase III domain-like | RNase III domain-like | 3 | 2 |  |
Homeodomain-like | FAD/NAD(P)-binding domain | 3 | 2 |  |
AN1-like Zinc finger | AN1-like Zinc finger | 3 | 2 |  |
Nucleotidylyl transferase | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 |  |
"Winged helix" DNA-binding domain | PH domain-like | 3 | 2 |  |
TRAF domain-like | TRAF domain-like | 3 | 3 |  |
L27 domain | SH3-domain | 3 | 1 |  |
RCC1/BLIP-II | Concanavalin A-like lectins/glucanases | 3 | 1 |  |
SAP domain | RING/U-box | 3 | 1 |  |
YWTD domain | Quinoprotein alcohol dehydrogenase-like | 3 | 2 |  |
FYVE/PHD zinc finger | SAP domain | 3 | 1 |  |
Carbohydrate-binding domain | beta-N-acetylhexosaminidase-like domain | 3 | 2 |  |
beta-sandwich domain of Sec23/24 | beta-beta-alpha zinc fingers | 3 | 2 |  |
ValRS/IleRS/LeuRS editing domain | tRNA-binding arm | 3 | 1 |  |
Alkaline phosphatase-like | His-Me finger endonucleases | 3 | 2 |  |
Bactericidal permeability-increasing protein, BPI | Bactericidal permeability-increasing protein, BPI | 3 | 3 |  |
Cap-Gly domain | Cap-Gly domain | 3 | 3 |  |
ACT-like | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 3 | 2 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 |  |
Metallo-dependent phosphatases | 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 3 | 2 |  |
Glucocorticoid receptor-like (DNA-binding domain) | BRCT domain | 3 | 3 |  |
Cysteine-rich domain | SAM/Pointed domain | 3 | 3 |  |
LDL receptor-like module | Growth factor receptor domain | 3 | 3 |  |
beta-beta-alpha zinc fingers | Formin homology 2 domain (FH2 domain) | 3 | 3 |  |
EF-hand | SH3-domain | 3 | 3 |  |
Concanavalin A-like lectins/glucanases | Complement control module/SCR domain | 3 | 3 |  |
Cadherin-like | Concanavalin A-like lectins/glucanases | 3 | 3 |  |
Homeodomain-like | POZ domain | 3 | 3 |  |
Acid proteases | UBA-like | 3 | 1 |  |
Myosin rod fragments | Tropomyosin | 3 | 2 |  |
alpha/beta-Hydrolases | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 3 | 1 |  |
Outer arm dynein light chain 1 | L domain-like | 3 | 3 |  |
Histone-fold | ARM repeat | 3 | 2 |  |
SH2 domain | GTPase activation domain, GAP | 3 | 3 |  |
TATA-box binding protein-like | DNA-glycosylase | 3 | 1 |  |
TGS-like | Class II aaRS and biotin synthetases | 3 | 2 |  |
Guanido kinase N-terminal domain | Glutamine synthetase/guanido kinase | 3 | 2 |  |
EGF/Laminin | Family A G protein-coupled receptor-like | 3 | 1 |  |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 |  |
DEATH domain | RBP11-like subunits of RNA polymerase | 3 | 1 |  |
Transcription factor IIA (TFIIA), alpha-helical domain | Transcription factor IIA (TFIIA), beta-barrel domain | 3 | 2 |  |
Concanavalin A-like lectins/glucanases | Hect, E3 ligase catalytic domain | 3 | 1 |  |
Mib/herc2 domain-like | Ankyrin repeat | 3 | 2 |  |
Hermes dimerisation domain | Ribonuclease H-like | 3 | 2 |  |
L27 domain | P-loop containing nucleoside triphosphate hydrolases | 3 | 1 |  |
Ubiquitin-like | Cap-Gly domain | 3 | 3 |  |
Integrin domains | EGF/Laminin | 3 | 2 |  |
PGBD-like | Hemopexin-like domain | 3 | 3 |  |
Cysteine proteinases | UBA-like | 3 | 2 |  |
Glutaminase/Asparaginase | Ankyrin repeat | 3 | 2 |  |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 3 | 3 |  |
MIR domain | MIR domain | 3 | 3 |  |
CCCH zinc finger | CCCH zinc finger | 3 | 2 |  |
TB module/8-cys domain | Growth factor receptor domain | 3 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-hand | 3 | 2 |  |
PsbU/PolX domain-like | Nucleotidyltransferase | 3 | 2 |  |
Growth factor receptor domain | Protein kinase-like (PK-like) | 3 | 3 |  |
PX domain | SH3-domain | 3 | 3 |  |
NAD(P)-binding Rossmann-fold domains | alpha/beta-Hydrolases | 3 | 2 |  |
RING/U-box | Calcium-dependent phosphotriesterase | 3 | 3 |  |
ARM repeat | UBA-like | 3 | 2 |  |
CRAL/TRIO domain | Spectrin repeat | 3 | 3 |  |
Amine oxidase N-terminal region | Amine oxidase N-terminal region | 3 | 1 |  |
Carbohydrate-binding domain | E set domains | 3 | 2 |  |
DEATH domain | Protein kinase-like (PK-like) | 3 | 1 |  |
C-type lectin-like | Immunoglobulin | 3 | 3 |  |
RING/U-box | WD40 repeat-like | 3 | 3 |  |
GYF domain | Chaperone J-domain | 3 | 1 |  |
WGR domain-like | Domain of poly(ADP-ribose) polymerase | 3 | 3 |  |
Snake toxin-like | Protein kinase-like (PK-like) | 3 | 3 |  |
Regulator of G-protein signaling, RGS | PX domain | 3 | 1 |  |
SH3-domain | GTPase activation domain, GAP | 3 | 3 |  |
Amine oxidase N-terminal region | Amine oxidase catalytic domain | 3 | 1 |  |
Nucleic acid-binding proteins | Translation proteins SH3-like domain | 3 | 2 |  |
DUSP-like | Cysteine proteinases | 3 | 3 |  |
Tudor/PWWP/MBT | RING/U-box | 3 | 2 |  |
Ankyrin repeat | ADP-ribosylation | 3 | 3 |  |
B-box zinc-binding domain | Calcium-dependent phosphotriesterase | 3 | 3 |  |
Invertebrate chitin-binding proteins | Trypsin-like serine proteases | 3 | 3 |  |
SNARE fusion complex | SNARE fusion complex | 3 | 2 |  |
ARM repeat | Chaperone J-domain | 3 | 1 |  |
Ypt/Rab-GAP domain of gyp1p | Rhodanese/Cell cycle control phosphatase | 3 | 2 |  |
CRAL/TRIO N-terminal domain | Supernatant protein factor (SPF), C-terminal domain | 3 | 1 |  |
Acyl-CoA dehydrogenase C-terminal domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 3 | 2 |  |
Growth factor receptor domain | Invertebrate chitin-binding proteins | 3 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | Ubiquitin-like | 3 | 3 |  |
EGF/Laminin | TB module/8-cys domain | 3 | 3 |  |
Phosphofructokinase | Phosphofructokinase | 3 | 1 |  |
RUN domain-like | RUN domain-like | 3 | 1 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 |  |
DNA polymerase beta, N-terminal domain-like | Nucleotidyltransferase | 3 | 2 |  |
Calponin-homology domain, CH-domain | PH domain-like | 3 | 1 |  |
(Phosphotyrosine protein) phosphatases II | FYVE/PHD zinc finger | 3 | 2 |  |
Transducin (heterotrimeric G protein), gamma chain | Regulator of G-protein signaling, RGS | 3 | 2 |  |
UBC-like | RING/U-box | 3 | 3 |  |
Ran binding protein zinc finger-like | Cysteine proteinases | 3 | 1 |  |
Chromo domain-like | Acyl-CoA N-acyltransferases (Nat) | 3 | 1 |  |
RNase III domain-like | dsRNA-binding domain-like | 3 | 2 |  |
Chaperone J-domain | Thioredoxin-like | 3 | 2 |  |
FnI-like domain | EGF/Laminin | 3 | 3 |  |
Complement control module/SCR domain | Growth factor receptor domain | 3 | 3 |  |
Ubiquitin-like | Acid proteases | 3 | 1 |  |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 3 | 2 |  |
Plexin repeat | Integrin domains | 3 | 2 |  |
CAD & PB1 domains | Protein kinase-like (PK-like) | 3 | 2 |  |
Galactose-binding domain-like | (Trans)glycosidases | 3 | 3 |  |
PA domain | Zn-dependent exopeptidases | 3 | 2 |  |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | tRNA-binding arm | 3 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 |  |
t-snare proteins | SNARE fusion complex | 3 | 2 |  |
RUN domain-like | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 3 | 1 |  |
ATP-dependent DNA ligase DNA-binding domain | BRCT domain | 3 | 3 |  |
MIR domain | IP3 receptor type 1 binding core, domain 2 | 3 | 3 |  |
L domain-like | Fibronectin type III | 3 | 3 |  |
beta-Galactosidase/glucuronidase domain | (Trans)glycosidases | 3 | 3 |  |
ARM repeat | GYF domain | 3 | 1 |  |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | P-loop containing nucleoside triphosphate hydrolases | 3 | 1 |  |
(Trans)glycosidases | E set domains | 3 | 2 |  |
CAD & PB1 domains | RING/U-box | 3 | 2 |  |
YWTD domain | Growth factor receptor domain | 3 | 3 |  |
Calponin-homology domain, CH-domain | Calponin-homology domain, CH-domain | 3 | 2 |  |
Serine protease inhibitors | LDL receptor-like module | 3 | 3 |  |
Ubiquitin-like | ARM repeat | 3 | 2 |  |
beta-N-acetylhexosaminidase-like domain | E set domains | 3 | 2 |  |
Toll/Interleukin receptor TIR domain | Toll/Interleukin receptor TIR domain | 3 | 2 |  |
Nucleotidylyl transferase | tRNA-binding arm | 3 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Tudor/PWWP/MBT | 3 | 3 |  |
"Winged helix" DNA-binding domain | SMAD/FHA domain | 3 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Homeodomain-like | 3 | 2 |  |
WD40 repeat-like | Hect, E3 ligase catalytic domain | 3 | 1 |  |
Plexin repeat | vWA-like | 3 | 2 |  |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 3 | 2 |  |
C-type lectin-like | Spermadhesin, CUB domain | 3 | 3 |  |
Carbon-nitrogen hydrolase | HIT-like | 3 | 1 |  |
Ubiquitin-like | SH3-domain | 3 | 3 |  |
HLH, helix-loop-helix DNA-binding domain | Orange domain-like | 3 | 1 |  |
Growth factor receptor domain | FnI-like domain | 2 | 2 |  |
Annexin | Annexin | 2 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 2 | 2 |  |
L domain-like | Concanavalin A-like lectins/glucanases | 2 | 2 |  |
NTF2-like | NTF2-like | 2 | 1 |  |
Thiolase-like | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
alpha-ketoacid dehydrogenase kinase, N-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 |  |
Trypsin-like serine proteases | Trypsin-like serine proteases | 2 | 2 |  |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 2 | 1 |  |
PurM C-terminal domain-like | Formyltransferase | 2 | 1 |  |
Invertebrate chitin-binding proteins | Glycoside hydrolase/deacetylase | 2 | 2 |  |
E set domains | AMPKBI-like | 2 | 1 |  |
Zn-dependent exopeptidases | Transferrin receptor-like dimerisation domain | 2 | 2 |  |
Nucleotidyltransferase | Retrovirus zinc finger-like domains | 2 | 1 |  |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 2 | 1 |  |
Thiolase-like | alpha/beta-Hydrolases | 2 | 1 |  |
Macro domain-like | Zn-dependent exopeptidases | 2 | 1 |  |
Ubiquitin-like | Cysteine proteinases | 2 | 2 |  |
Acyl-CoA N-acyltransferases (Nat) | Bromodomain | 2 | 1 |  |
Aldolase | post-HMGL domain-like | 2 | 1 |  |
PurM C-terminal domain-like | PurM C-terminal domain-like | 2 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Hect, E3 ligase catalytic domain | 2 | 1 |  |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 |  |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 2 | 2 |  |
Glutathione synthetase ATP-binding domain-like | PurM N-terminal domain-like | 2 | 1 |  |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 2 | 2 |  |
Thyroglobulin type-1 domain | Thyroglobulin type-1 domain | 2 | 2 |  |
HAND domain of the nucleosome remodeling ATPase ISWI | Homeodomain-like | 2 | 1 |  |
PP2C-like | PP2C-like | 2 | 2 |  |
Growth factor receptor domain | TSP-1 type 1 repeat | 2 | 2 |  |
Nucleotidylyl transferase | Ribosomal protein L25-like | 2 | 2 |  |
WD40 repeat-like | FYVE/PHD zinc finger | 2 | 2 |  |
Translation proteins | ThrRS/AlaRS common domain | 2 | 1 |  |
Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 2 | 2 |  |
Zinc hairpin stack | RING/U-box | 2 | 1 |  |
Tex N-terminal region-like | Ribonuclease H-like | 2 | 2 |  |
E set domains | Terpenoid cyclases/Protein prenyltransferases | 2 | 1 |  |
CCHHC domain | CCHHC domain | 2 | 1 |  |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 2 | 1 |  |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 2 | 2 |  |
Spectrin repeat | RING/U-box | 2 | 2 |  |
Rudiment single hybrid motif | Formyltransferase | 2 | 1 |  |
RNI-like | RNI-like | 2 | 2 |  |
Initiation factor IF2/eIF5b, domain 3 | Translation proteins | 2 | 2 |  |
CAD & PB1 domains | UBA-like | 2 | 1 |  |
Cap-Gly domain | L domain-like | 2 | 2 |  |
PDZ domain-like | DEATH domain | 2 | 1 |  |
Putative DNA-binding domain | SAND domain-like | 2 | 1 |  |
EF-hand | PX domain | 2 | 1 |  |
Nucleotidyltransferase | Nucleotidyltransferase | 2 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 2 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | alpha/beta-Hydrolases | 2 | 1 |  |
WW domain | PIN domain-like | 2 | 1 |  |
Thiolase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 2 | 1 |  |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Elongation factor TFIIS domain 2 | 2 | 1 |  |
RCC1/BLIP-II | Cytochrome b5-like heme/steroid binding domain | 2 | 1 |  |
Stathmin | Stathmin | 2 | 1 |  |
Radical SAM enzymes | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 |  |
Ankyrin repeat | WD40 repeat-like | 2 | 1 |  |
Pentapeptide repeat-like | Pentapeptide repeat-like | 2 | 2 |  |
PK beta-barrel domain-like | PK C-terminal domain-like | 2 | 1 |  |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 2 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | Tudor/PWWP/MBT | 2 | 2 |  |
Fibronectin type III | YWTD domain | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | RNA-binding domain, RBD | 2 | 2 |  |
BRCT domain | Ankyrin repeat | 2 | 2 |  |
post-HMGL domain-like | Single hybrid motif | 2 | 1 |  |
Sema domain | Protein kinase-like (PK-like) | 2 | 2 |  |
YWTD domain | YVTN repeat-like/Quinoprotein amine dehydrogenase | 2 | 2 |  |
PLC-like phosphodiesterases | C-terminal domain of PLC-beta | 2 | 2 |  |
Kazal-type serine protease inhibitors | EGF/Laminin | 2 | 1 |  |
YVTN repeat-like/Quinoprotein amine dehydrogenase | YVTN repeat-like/Quinoprotein amine dehydrogenase | 2 | 2 |  |
Voltage-gated potassium channels | Small-conductance potassium channel | 2 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Aldolase | 2 | 1 |  |
PDZ domain-like | BAR/IMD domain-like | 2 | 1 |  |
Concanavalin A-like lectins/glucanases | SRCR-like | 2 | 2 |  |
TSP-1 type 1 repeat | Trypsin-like serine proteases | 2 | 1 |  |
Rap30/74 interaction domains | "Winged helix" DNA-binding domain | 2 | 2 |  |
Cytochrome b5-like heme/steroid binding domain | Mib/herc2 domain-like | 2 | 1 |  |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 2 | 1 |  |
Ribonuclease H-like | RuvA domain 2-like | 2 | 2 |  |
Spectrin repeat | WW domain | 2 | 2 |  |
PAH2 domain | PAH2 domain | 2 | 2 |  |
Galactose-binding domain-like | (Phosphotyrosine protein) phosphatases II | 2 | 2 |  |
PAP/OAS1 substrate-binding domain | Retrovirus zinc finger-like domains | 2 | 1 |  |
UBC-like | Endosomal sorting complex assembly domain | 2 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | C-terminal domain of PLC-beta | 2 | 2 |  |
Cysteine proteinases | Galactose-binding domain-like | 2 | 2 |  |
LDL receptor-like module | Alpha-macroglobulin receptor domain | 2 | 1 |  |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 2 | 1 |  |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 2 | 2 |  |
BRCT domain | WGR domain-like | 2 | 2 |  |
E set domains | Alpha-macroglobulin receptor domain | 2 | 1 |  |
Second domain of FERM | Protein kinase-like (PK-like) | 2 | 2 |  |
SH2 domain | DNase I-like | 2 | 1 |  |
Immunoglobulin | Family A G protein-coupled receptor-like | 2 | 1 |  |
Voltage-gated potassium channels | EF-hand | 2 | 1 |  |
FKBP-like | Myosin rod fragments | 2 | 1 |  |
HR1 repeat | HR1 repeat | 2 | 1 |  |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | GroES-like | 2 | 1 |  |
Galactose-binding domain-like | Growth factor receptor domain | 2 | 2 |  |
WD40 repeat-like | Ypt/Rab-GAP domain of gyp1p | 2 | 2 |  |
Bromodomain | Nuclear receptor coactivator interlocking domain | 2 | 2 |  |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | alpha/beta-Hydrolases | 2 | 1 |  |
E set domains | Protein kinase-like (PK-like) | 2 | 2 |  |
Thiolase-like | GroES-like | 2 | 1 |  |
cAMP-binding domain-like | Ubiquitin-like | 2 | 2 |  |
Kelch motif | EGF/Laminin | 2 | 2 |  |
Glutathione synthetase ATP-binding domain-like | post-HMGL domain-like | 2 | 1 |  |
"Winged helix" DNA-binding domain | dsRNA-binding domain-like | 2 | 2 |  |
Second domain of FERM | FAT domain of focal adhesion kinase | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | DEATH domain | 2 | 2 |  |
Spermadhesin, CUB domain | Kelch motif | 2 | 2 |  |
Alkaline phosphatase-like | Alkaline phosphatase-like | 2 | 1 |  |
PAP/OAS1 substrate-binding domain | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 2 | 1 |  |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 2 | 2 |  |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 2 | 1 |  |
Bromodomain | RING/U-box | 2 | 2 |  |
Cysteine proteinases | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 1 |  |
Restriction endonuclease-like | RuvA domain 2-like | 2 | 1 |  |
SET domain | WW domain | 2 | 1 |  |
EF-hand | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 |  |
PreATP-grasp domain | Formyltransferase | 2 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | RING/U-box | 2 | 1 |  |
BRCT domain | Domain of poly(ADP-ribose) polymerase | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | LigT-like | 2 | 1 |  |
HR1 repeat | Protein kinase-like (PK-like) | 2 | 1 |  |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 2 | 1 |  |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | Eukaryotic DNA topoisomerase I, dispensable insert domain | 2 | 1 |  |
Protein kinase-like (PK-like) | MIT domain | 2 | 2 |  |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 2 | 1 |  |
Cadherin-like | Dystroglycan, domain 2 | 2 | 2 |  |
Fibrinogen C-terminal domain-like | Growth factor receptor domain | 2 | 1 |  |
Pectin lyase-like | Pectin lyase-like | 2 | 2 |  |
ARM repeat | WWE domain | 2 | 2 |  |
ACP-like | alpha/beta-Hydrolases | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | PRTase-like | 2 | 1 |  |
Bromodomain | TAZ domain | 2 | 2 |  |
Metalloproteases ("zincins"), catalytic domain | Hairpin loop containing domain-like | 2 | 2 |  |
BPTI-like | Di-copper centre-containing domain | 2 | 1 |  |
PreATP-grasp domain | Aldolase | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | SET domain | 2 | 1 |  |
CHY zinc finger-like | RING/U-box | 2 | 1 |  |
RING/U-box | TAZ domain | 2 | 2 |  |
PurM N-terminal domain-like | Formyltransferase | 2 | 1 |  |
Aldolase | Single hybrid motif | 2 | 1 |  |
ARM repeat | Rap/Ran-GAP | 2 | 2 |  |
Cdc48 domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
PUA domain-like | RING/U-box | 2 | 2 |  |
Rudiment single hybrid motif | PurM N-terminal domain-like | 2 | 1 |  |
TSP type-3 repeat | TSP type-3 repeat | 2 | 2 |  |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain II | 2 | 2 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 2 | 1 |  |
LDL receptor-like module | L domain-like | 2 | 2 |  |
FYVE/PHD zinc finger | SAM/Pointed domain | 2 | 1 |  |
L domain-like | EGF/Laminin | 2 | 2 |  |
TPR-like | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 2 | 2 |  |
LDL receptor-like module | Complement control module/SCR domain | 2 | 2 |  |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
RUN domain-like | Supernatant protein factor (SPF), C-terminal domain | 2 | 1 |  |
Nucleotidyltransferase | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 2 | 1 |  |
UBA-like | RNA-binding domain, RBD | 2 | 1 |  |
PAZ domain | dsRNA-binding domain-like | 2 | 1 |  |
EGF/Laminin | Methyl-accepting chemotaxis protein (MCP) signaling domain | 2 | 2 |  |
EF-hand | SH2 domain | 2 | 2 |  |
B-box zinc-binding domain | TRAF domain-like | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 2 | 2 |  |
Zn-dependent exopeptidases | Zn-dependent exopeptidases | 2 | 2 |  |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | VPS9 domain | 2 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | Retrovirus zinc finger-like domains | 2 | 1 |  |
HR1 repeat | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 2 | 2 |  |
Spermadhesin, CUB domain | Concanavalin A-like lectins/glucanases | 2 | 1 |  |
Toll/Interleukin receptor TIR domain | SAM/Pointed domain | 2 | 2 |  |
TSP-1 type 1 repeat | Hairpin loop containing domain-like | 2 | 2 |  |
Heat shock protein 70kD (HSP70), C-terminal subdomain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 2 | 1 |  |
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | Protein kinase-like (PK-like) | 2 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Formyltransferase | 2 | 1 |  |
S15/NS1 RNA-binding domain | Class II aaRS and biotin synthetases | 2 | 2 |  |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase | 2 | 2 |  |
TAZ domain | Nuclear receptor coactivator interlocking domain | 2 | 2 |  |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 2 | 1 |  |
Glycoside hydrolase/deacetylase | Glycoside hydrolase/deacetylase | 2 | 1 |  |
RING/U-box | Nuclear receptor coactivator interlocking domain | 2 | 2 |  |
FYVE/PHD zinc finger | Supernatant protein factor (SPF), C-terminal domain | 2 | 1 |  |
Actin depolymerizing proteins | VHP, Villin headpiece domain | 2 | 2 |  |
EGF/Laminin | C-type lectin-like | 2 | 2 |  |
RING/U-box | Protein kinase-like (PK-like) | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | HAND domain of the nucleosome remodeling ATPase ISWI | 2 | 1 |  |
YVTN repeat-like/Quinoprotein amine dehydrogenase | Quinoprotein alcohol dehydrogenase-like | 2 | 2 |  |
Carbamate kinase-like | ALDH-like | 2 | 1 |  |
GMP synthetase C-terminal dimerisation domain | GMP synthetase C-terminal dimerisation domain | 2 | 1 |  |
TGS-like | Class II aaRS ABD-related | 2 | 1 |  |
PurM C-terminal domain-like | Class I glutamine amidotransferase-like | 2 | 1 |  |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 2 | 1 |  |
ARM repeat | L domain-like | 2 | 1 |  |
HLH, helix-loop-helix DNA-binding domain | Formin homology 2 domain (FH2 domain) | 2 | 2 |  |
FMN-linked oxidoreductases | alpha-helical ferredoxin | 2 | 2 |  |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | ACP-like | 2 | 1 |  |
FabD/lysophospholipase-like | GroES-like | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | ADP-ribosylation | 2 | 2 |  |
SET domain | RuBisCo LSMT C-terminal, substrate-binding domain | 2 | 2 |  |
SH3-domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 |  |
L domain-like | Actin depolymerizing proteins | 2 | 1 |  |
Ankyrin repeat | POZ domain | 2 | 2 |  |
FabD/lysophospholipase-like | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
FabD/lysophospholipase-like | alpha/beta-Hydrolases | 2 | 1 |  |
p53-like transcription factors | DEATH domain | 2 | 1 |  |
Periplasmic binding protein-like II | Periplasmic binding protein-like II | 2 | 1 |  |
RUN domain-like | FYVE/PHD zinc finger | 2 | 1 |  |
PreATP-grasp domain | PurM N-terminal domain-like | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Domain of poly(ADP-ribose) polymerase | 2 | 2 |  |
Concanavalin A-like lectins/glucanases | EF-hand | 2 | 1 |  |
Staphylococcal nuclease | Tudor/PWWP/MBT | 2 | 2 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | DBL homology domain (DH-domain) | 2 | 1 |  |
DEATH domain | Toll/Interleukin receptor TIR domain | 2 | 2 |  |
beta-beta-alpha zinc fingers | WW domain | 2 | 1 |  |
Plexin repeat | Integrin beta tail domain | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | RNase III domain-like | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Quinoprotein alcohol dehydrogenase-like | 2 | 2 |  |
Cadherin-like | EGF/Laminin | 2 | 2 |  |
TPR-like | Chaperone J-domain | 2 | 2 |  |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Second domain of FERM | 2 | 2 |  |
Ankyrin repeat | Second domain of FERM | 2 | 1 |  |
FYVE/PHD zinc finger | "Winged helix" DNA-binding domain | 2 | 2 |  |
DNase I-like | RNA-binding domain, RBD | 2 | 1 |  |
Plexin repeat | GTPase activation domain, GAP | 2 | 2 |  |
MIT domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Tudor/PWWP/MBT | Galactose-binding domain-like | 2 | 1 |  |
Polo-box domain | Polo-box domain | 2 | 1 |  |
L domain-like | Ubiquitin-like | 2 | 2 |  |
RCC1/BLIP-II | DBL homology domain (DH-domain) | 2 | 1 |  |
Rudiment single hybrid motif | Aldolase | 2 | 1 |  |
E set domains | DEATH domain | 2 | 1 |  |
HAD-like | HAD-like | 2 | 2 |  |
Quinoprotein alcohol dehydrogenase-like | TPR-like | 2 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Galactose-binding domain-like | 2 | 1 |  |
PurM N-terminal domain-like | PurM N-terminal domain-like | 2 | 1 |  |
Macro domain-like | RING/U-box | 2 | 2 |  |
WD40 repeat-like | Ribonuclease H-like | 2 | 1 |  |
LDL receptor-like module | Terpenoid cyclases/Protein prenyltransferases | 2 | 1 |  |
S15/NS1 RNA-binding domain | Class II aaRS ABD-related | 2 | 2 |  |
Cysteine-rich domain | SH2 domain | 2 | 2 |  |
Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 2 | 1 |  |
EGF/Laminin | BPTI-like | 2 | 1 |  |
PH domain-like | FAT domain of focal adhesion kinase | 2 | 2 |  |
Calcium-dependent phosphotriesterase | YVTN repeat-like/Quinoprotein amine dehydrogenase | 2 | 2 |  |
UDP-Glycosyltransferase/glycogen phosphorylase | UDP-Glycosyltransferase/glycogen phosphorylase | 2 | 1 |  |
Starch-binding domain-like | PLC-like phosphodiesterases | 2 | 1 |  |
L domain-like | RING/U-box | 2 | 1 |  |
Tudor/PWWP/MBT | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
Hairpin loop containing domain-like | Trypsin-like serine proteases | 2 | 2 |  |
PRTase-like | PRTase-like | 2 | 2 |  |
Galactose-binding domain-like | TSP-1 type 1 repeat | 2 | 1 |  |
Ubiquitin-like | Ankyrin repeat | 2 | 2 |  |
Class II aaRS and biotin synthetases | Translation proteins | 2 | 1 |  |
FMN-linked oxidoreductases | Nucleotide-binding domain | 2 | 2 |  |
CHY zinc finger-like | Zinc hairpin stack | 2 | 1 |  |
Cysteine proteinases | beta-sandwich domain of Sec23/24 | 2 | 2 |  |
FabD/lysophospholipase-like | EF-hand | 2 | 2 |  |
ADC-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | EGF/Laminin | 2 | 1 |  |
L domain-like | Snake toxin-like | 2 | 2 |  |
VPS9 domain | Ankyrin repeat | 2 | 1 |  |
Tricorn protease domain 2 | SOCS box-like | 2 | 1 |  |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 2 | 1 |  |
RCC1/BLIP-II | Tudor/PWWP/MBT | 2 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 2 | 1 |  |
Actin-crosslinking proteins | Actin-crosslinking proteins | 2 | 2 |  |
NSFL1 (p97 ATPase) cofactor p47, SEP domain | Ubiquitin-like | 2 | 2 |  |
L domain-like | NTF2-like | 2 | 1 |  |
SMAD MH1 domain | SMAD/FHA domain | 2 | 1 |  |
Tudor/PWWP/MBT | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
Formyltransferase | FMT C-terminal domain-like | 2 | 2 |  |
Tex N-terminal region-like | RuvA domain 2-like | 2 | 2 |  |
PDZ domain-like | (Phosphotyrosine protein) phosphatases II | 2 | 2 |  |
Surp module (SWAP domain) | Surp module (SWAP domain) | 2 | 2 |  |
Thiolase-like | ACP-like | 2 | 1 |  |
TB module/8-cys domain | TB module/8-cys domain | 2 | 2 |  |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 2 | 1 |  |
PAP/OAS1 substrate-binding domain | PAP/OAS1 substrate-binding domain | 2 | 1 |  |
Multidrug efflux transporter AcrB transmembrane domain | WD40 repeat-like | 2 | 1 |  |
DNase I-like | SAM/Pointed domain | 2 | 1 |  |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 2 | 1 |  |
GST C-terminal domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
ARM repeat | Zn-dependent exopeptidases | 2 | 1 |  |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | DNA breaking-rejoining enzymes | 2 | 1 |  |
Family A G protein-coupled receptor-like | "Winged helix" DNA-binding domain | 2 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | GroES-like | 2 | 1 |  |
GroES-like | alpha/beta-Hydrolases | 2 | 1 |  |
HMA, heavy metal-associated domain | HAD-like | 2 | 2 |  |
Calpain large subunit, middle domain (domain III) | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 1 |  |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 2 | 2 |  |
Protein kinase-like (PK-like) | FAT domain of focal adhesion kinase | 2 | 2 |  |
Zinc beta-ribbon | Cyclin-like | 2 | 2 |  |
vWA-like | Complement control module/SCR domain | 2 | 2 |  |
RNI-like | Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain | 2 | 1 |  |
Plexin repeat | EGF/Laminin | 2 | 1 |  |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 2 | 2 |  |
Thiolase-like | FabD/lysophospholipase-like | 2 | 1 |  |
L domain-like | WD40 repeat-like | 2 | 1 |  |
Tudor/PWWP/MBT | Hect, E3 ligase catalytic domain | 2 | 1 |  |
Avidin/streptavidin | Avidin/streptavidin | 2 | 1 |  |
Ankyrin repeat | Galactose-binding domain-like | 2 | 2 |  |
Sema domain | E set domains | 2 | 2 |  |
MIT domain | MIT domain | 2 | 2 |  |
LDL receptor-like module | Hairpin loop containing domain-like | 2 | 2 |  |
RuvA domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 |  |
Integrin domains | Integrin beta tail domain | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Myosin rod fragments | 2 | 2 |  |
Ankyrin repeat | Hect, E3 ligase catalytic domain | 2 | 2 |  |
Tudor/PWWP/MBT | 6-phosphogluconate dehydrogenase C-terminal domain-like | 2 | 1 |  |
cAMP-binding domain-like | Protein kinase-like (PK-like) | 2 | 1 |  |
vWA-like | Integrin beta tail domain | 2 | 1 |  |
Translational machinery components | L30e-like | 2 | 2 |  |
Regulator of G-protein signaling, RGS | Regulator of G-protein signaling, RGS | 2 | 2 |  |
SAM/Pointed domain | ADP-ribosylation | 2 | 2 |  |
BRCT domain | ADP-ribosylation | 2 | 2 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | WW domain | 2 | 2 |  |
Single hybrid motif | Single hybrid motif | 2 | 2 |  |
p53-like transcription factors | Ankyrin repeat | 2 | 1 |  |
alpha-helical ferredoxin | Nucleotide-binding domain | 2 | 2 |  |
Protein kinase-like (PK-like) | UBA-like | 2 | 2 |  |
PreATP-grasp domain | post-HMGL domain-like | 2 | 1 |  |
Ubiquitin-like | FAT domain of focal adhesion kinase | 2 | 2 |  |
DBL homology domain (DH-domain) | Ras GEF | 2 | 2 |  |
Cytochrome b5-like heme/steroid binding domain | Tudor/PWWP/MBT | 2 | 1 |  |
HMA, heavy metal-associated domain | Metal cation-transporting ATPase, ATP-binding domain N | 2 | 2 |  |
TPR-like | Clavaminate synthase-like | 2 | 2 |  |
Methyl-accepting chemotaxis protein (MCP) signaling domain | Concanavalin A-like lectins/glucanases | 2 | 2 |  |
His-Me finger endonucleases | HIT/MYND zinc finger-like | 2 | 1 |  |
PDZ domain-like | Formin homology 2 domain (FH2 domain) | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | PAZ domain | 2 | 1 |  |
BRCT domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 |  |
EGF/Laminin | Heme-dependent peroxidases | 2 | 1 |  |
EF-hand | Mannose 6-phosphate receptor domain | 2 | 2 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Smc hinge domain | 2 | 1 |  |
TPR-like | "Winged helix" DNA-binding domain | 2 | 2 |  |
PAZ domain | RNase III domain-like | 2 | 1 |  |
L domain-like | SAM/Pointed domain | 2 | 1 |  |
Protein kinase-like (PK-like) | RNA-binding domain, RBD | 2 | 1 |  |
EF-hand | NAD kinase/diacylglycerol kinase-like | 2 | 1 |  |
ADC-like | Cdc48 domain 2-like | 2 | 1 |  |
ARM repeat | RING/U-box | 2 | 2 |  |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | FYVE/PHD zinc finger | 2 | 1 |  |
WD40 repeat-like | NHL repeat | 2 | 2 |  |
RCC1/BLIP-II | Mib/herc2 domain-like | 2 | 1 |  |
Serine protease inhibitors | Hairpin loop containing domain-like | 2 | 2 |  |
FabD/lysophospholipase-like | ACP-like | 2 | 1 |  |
LDL receptor-like module | Mannose 6-phosphate receptor domain | 2 | 2 |  |
PH domain-like | Moesin tail domain | 2 | 1 |  |
Metallo-dependent phosphatases | EF-hand | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | WGR domain-like | 2 | 2 |  |
Glutathione synthetase ATP-binding domain-like | PurM C-terminal domain-like | 2 | 1 |  |
DNA breaking-rejoining enzymes | Eukaryotic DNA topoisomerase I, dispensable insert domain | 2 | 1 |  |
LDL receptor-like module | FnI-like domain | 2 | 2 |  |
WD40 repeat-like | Cysteine proteinases | 2 | 1 |  |
RNA-binding domain, RBD | PWI domain | 2 | 1 |  |
PDZ domain-like | Second domain of FERM | 2 | 1 |  |
HCP-like | HCP-like | 2 | 2 |  |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 2 | 1 |  |
RNA-binding domain, RBD | HIT/MYND zinc finger-like | 2 | 1 |  |
Hairpin loop containing domain-like | SRCR-like | 2 | 2 |  |
vWA-like | Invertebrate chitin-binding proteins | 2 | 2 |  |
Granulin repeat | Granulin repeat | 2 | 2 |  |
L domain-like | DEATH domain | 2 | 2 |  |
EGF/Laminin | Di-copper centre-containing domain | 2 | 1 |  |
Mib/herc2 domain-like | Tudor/PWWP/MBT | 2 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | Galactose oxidase, central domain | 2 | 1 |  |
E set domains | GTPase activation domain, GAP | 2 | 2 |  |
GroES-like | ACP-like | 2 | 1 |  |
Saposin | Saposin | 2 | 2 |  |
Plexin repeat | Protein kinase-like (PK-like) | 2 | 2 |  |
Rudiment single hybrid motif | PurM C-terminal domain-like | 2 | 1 |  |
PreATP-grasp domain | PurM C-terminal domain-like | 2 | 1 |  |
Pre-PUA domain | PUA domain-like | 2 | 1 |  |
PX domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 |  |
SH2 domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 |  |
F1F0 ATP synthase subunit C | F1F0 ATP synthase subunit C | 2 | 2 |  |
Thiolase-like | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
CAD & PB1 domains | Cysteine-rich domain | 2 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | Complement control module/SCR domain | 2 | 2 |  |
Cation efflux protein transmembrane domain-like | Cation efflux protein transmembrane domain-like | 2 | 1 |  |
"Winged helix" DNA-binding domain | E set domains | 2 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | ACP-like | 2 | 1 |  |
RNA-binding domain, RBD | PABC (PABP) domain | 2 | 1 |  |
UBC-like | Ribosomal protein S5 domain 2-like | 2 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
NAD(P)-binding Rossmann-fold domains | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 |  |
EF-hand | WD40 repeat-like | 2 | 2 |  |
HLH, helix-loop-helix DNA-binding domain | HMG-box | 2 | 2 |  |
GTPase activation domain, GAP | VPS9 domain | 2 | 1 |  |
ARM repeat | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 2 | 2 |  |
Acetyl-CoA synthetase-like | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
HSP20-like chaperones | TPR-like | 2 | 2 |  |
RING/U-box | Hect, E3 ligase catalytic domain | 2 | 1 |  |
HAD-like | FAD/NAD(P)-binding domain | 2 | 2 |  |
Glucocorticoid receptor-like (DNA-binding domain) | AN1-like Zinc finger | 2 | 1 |  |
cAMP-binding domain-like | Ras GEF | 2 | 2 |  |
Growth factor receptor domain | NHL repeat | 2 | 1 |  |
PurM N-terminal domain-like | Class I glutamine amidotransferase-like | 2 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Rudiment single hybrid motif | post-HMGL domain-like | 2 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 2 | 1 |  |
NAD kinase/diacylglycerol kinase-like | SAM/Pointed domain | 2 | 2 |  |
Clathrin heavy-chain terminal domain | ARM repeat | 2 | 1 |  |
Cysteine proteinases | Ribonuclease H-like | 2 | 1 |  |
POZ domain | TRAF domain-like | 2 | 2 |  |
HMA, heavy metal-associated domain | HMA, heavy metal-associated domain | 2 | 2 |  |
ARM repeat | Hect, E3 ligase catalytic domain | 2 | 2 |  |
DBL homology domain (DH-domain) | BAR/IMD domain-like | 2 | 2 |  |
NAD(P)-binding Rossmann-fold domains | SCP-like | 2 | 2 |  |
FabD/lysophospholipase-like | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
Kazal-type serine protease inhibitors | Concanavalin A-like lectins/glucanases | 2 | 1 |  |
A DNA-binding domain in eukaryotic transcription factors | Leucine zipper domain | 2 | 2 |  |
C-type lectin-like | Complement control module/SCR domain | 2 | 2 |  |
L domain-like | ADP-ribosylglycohydrolase | 2 | 1 |  |
LDL receptor-like module | EF-hand | 2 | 2 |  |
Taf5 N-terminal domain-like | WD40 repeat-like | 2 | 1 |  |
beta-beta-alpha zinc fingers | Leucine zipper domain | 1 | 1 |  |
Ribonuclease H-like | Zinc finger domain of DNA polymerase-alpha | 1 | 1 |  |
Kazal-type serine protease inhibitors | Fibronectin type III | 1 | 1 |  |
Doublecortin (DC) | Pentapeptide repeat-like | 1 | 1 |  |
Adenine nucleotide alpha hydrolases-like | YjgF-like | 1 | 1 |  |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Voltage-gated potassium channels | 1 | 1 |  |
NHL repeat | Calcium-dependent phosphotriesterase | 1 | 1 |  |
FYSH domain | Hypothetical protein AF0491, middle domain | 1 | 1 |  |
Somatomedin B domain | Family A G protein-coupled receptor-like | 1 | 1 |  |
ISP transmembrane anchor | ISP domain | 1 | 1 |  |
Regulator of G-protein signaling, RGS | Retrovirus zinc finger-like domains | 1 | 1 |  |
Nucleotidylyl transferase | Class II aaRS and biotin synthetases | 1 | 1 |  |
TRAF domain-like | NRDP1 C-terminal domain-like | 1 | 1 |  |
FYVE/PHD zinc finger | SMAD/FHA domain | 1 | 1 |  |
vWA-like | Cysteine-rich domain | 1 | 1 |  |
F-box domain | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | Fibrinogen C-terminal domain-like | 1 | 1 |  |
Nucleotidylyl transferase | Class II aaRS ABD-related | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Chaperone J-domain | 1 | 1 |  |
Thioredoxin-like | NHL repeat | 1 | 1 |  |
Bet v1-like | Bet v1-like | 1 | 1 |  |
FabD/lysophospholipase-like | FabD/lysophospholipase-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 1 | 1 |  |
S15/NS1 RNA-binding domain | S15/NS1 RNA-binding domain | 1 | 1 |  |
WWE domain | ADP-ribosylation | 1 | 1 |  |
ARM repeat | Lipovitellin-phosvitin complex, superhelical domain | 1 | 1 |  |
GIY-YIG endonuclease | RING/U-box | 1 | 1 |  |
NAD-binding domain of HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | 1 | 1 |  |
Immunoglobulin | Trypsin-like serine proteases | 1 | 1 |  |
beta-beta-alpha zinc fingers | Phage fibre proteins | 1 | 1 |  |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 1 | 1 |  |
(Trans)glycosidases | Six-hairpin glycosidases | 1 | 1 |  |
L domain-like | PP2C-like | 1 | 1 |  |
Kazal-type serine protease inhibitors | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
PH domain-like | Family A G protein-coupled receptor-like | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Protein kinase-like (PK-like) | 1 | 1 |  |
ARID-like | Chromo domain-like | 1 | 1 |  |
F-box domain | SMI1/KNR4-like | 1 | 1 |  |
GST C-terminal domain-like | eEF-1beta-like | 1 | 1 |  |
ENTH/VHS domain | Clathrin adaptor appendage domain | 1 | 1 |  |
RNA-binding domain, RBD | Class II aaRS ABD-related | 1 | 1 |  |
Immunoglobulin | Caspase-like | 1 | 1 |  |
PR-1-like | PR-1-like | 1 | 1 |  |
HAD-like | Protein kinase-like (PK-like) | 1 | 1 |  |
ACP-like | ALDH-like | 1 | 1 |  |
PA domain | Transferrin receptor-like dimerisation domain | 1 | 1 |  |
p53-like transcription factors | SH2 domain | 1 | 1 |  |
Ribonuclease H-like | CCCH zinc finger | 1 | 1 |  |
Protein kinase-like (PK-like) | BEACH domain | 1 | 1 |  |
Macro domain-like | CRAL/TRIO domain | 1 | 1 |  |
Doublecortin (DC) | POZ domain | 1 | 1 |  |
ARID-like | Clavaminate synthase-like | 1 | 1 |  |
SRCR-like | Pectin lyase-like | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
Sec63 N-terminal domain-like | Ribonuclease H-like | 1 | 1 |  |
SH2 domain | Ankyrin repeat | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Riboflavin synthase domain-like | 1 | 1 |  |
Surp module (SWAP domain) | Ubiquitin-like | 1 | 1 |  |
NHL repeat | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
DEATH domain | RNI-like | 1 | 1 |  |
Subtilisin-like | Growth factor receptor domain | 1 | 1 |  |
PUA domain-like | eIF1-like | 1 | 1 |  |
GroES-like | GroES-like | 1 | 1 |  |
Rad51 N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Serine protease inhibitors | EGF/Laminin | 1 | 1 |  |
Nqo1 FMN-binding domain-like | Nqo1 middle domain-like | 1 | 1 |  |
PDZ domain-like | Ras GEF | 1 | 1 |  |
WD40 repeat-like | Nucleoporin domain | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | FF domain | 1 | 1 |  |
Actin-like ATPase domain | AF1104-like | 1 | 1 |  |
HAD-like | BRCT domain | 1 | 1 |  |
Chromo domain-like | ClpP/crotonase | 1 | 1 |  |
Peptidase/esterase 'gauge' domain | alpha/beta-Hydrolases | 1 | 1 |  |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 1 | 1 |  |
Ubiquitin-like | Zn-binding ribosomal proteins | 1 | 1 |  |
C-type lectin-like | Growth factor receptor domain | 1 | 1 |  |
Ankyrin repeat | FabD/lysophospholipase-like | 1 | 1 |  |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 |  |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 |  |
FnI-like domain | Leech antihemostatic proteins | 1 | 1 |  |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 |  |
Kringle-like | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 |  |
FYVE/PHD zinc finger | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 |  |
Ribonuclease H-like | Ribonuclease H-like | 1 | 1 |  |
SAM/Pointed domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
beta-Galactosidase/glucuronidase domain | beta-Galactosidase/glucuronidase domain | 1 | 1 |  |
FYVE/PHD zinc finger | BRK domain-like | 1 | 1 |  |
Protein kinase-like (PK-like) | KA1-like | 1 | 1 |  |
Plexin repeat | Plexin repeat | 1 | 1 |  |
Soluble quinoprotein glucose dehydrogenase | RING/U-box | 1 | 1 |  |
RING/U-box | NRDP1 C-terminal domain-like | 1 | 1 |  |
Nucleic acid-binding proteins | TPR-like | 1 | 1 |  |
Ankyrin repeat | YWTD domain | 1 | 1 |  |
Ankyrin repeat | HIT/MYND zinc finger-like | 1 | 1 |  |
N-terminal domain of cbl (N-cbl) | EF-hand | 1 | 1 |  |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | cAMP-binding domain-like | 1 | 1 |  |
Ubiquitin-like | NAD kinase/diacylglycerol kinase-like | 1 | 1 |  |
FYVE/PHD zinc finger | EF-hand | 1 | 1 |  |
TAZ domain | Kix domain of CBP (creb binding protein) | 1 | 1 |  |
PUG domain-like | Ubiquitin-like | 1 | 1 |  |
USP8 N-terminal domain-like | WW domain | 1 | 1 |  |
SWIB/MDM2 domain | eIF1-like | 1 | 1 |  |
Galactose oxidase, central domain | Galactose oxidase, central domain | 1 | 1 |  |
Immunoglobulin | Heme-dependent peroxidases | 1 | 1 |  |
Homocysteine S-methyltransferase | Dihydropteroate synthetase-like | 1 | 1 |  |
CBS-domain pair | CBS-domain pair | 1 | 1 |  |
UBA-like | DNase I-like | 1 | 1 |  |
Tudor/PWWP/MBT | HIV integrase-binding domain | 1 | 1 |  |
Second domain of FERM | RING/U-box | 1 | 1 |  |
Sema domain | Immunoglobulin | 1 | 1 |  |
RING/U-box | CCCH zinc finger | 1 | 1 |  |
SMI1/KNR4-like | ApaG-like | 1 | 1 |  |
ALDH-like | ALDH-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | GTPase activation domain, GAP | 1 | 1 |  |
Growth factor receptor domain | Notch domain | 1 | 1 |  |
TSP type-3 repeat | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Ankyrin repeat | RNI-like | 1 | 1 |  |
SAP domain | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain I | 1 | 1 |  |
C-type lectin-like | Fibronectin type III | 1 | 1 |  |
Acyl-CoA N-acyltransferases (Nat) | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 |  |
FAD/NAD(P)-binding domain | 4Fe-4S ferredoxins | 1 | 1 |  |
BRCT domain | Nucleotidyltransferase | 1 | 1 |  |
MIT domain | Cysteine proteinases | 1 | 1 |  |
Formiminotransferase domain of formiminotransferase-cyclodeaminase. | Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 1 | 1 |  |
SMAD/FHA domain | RING/U-box | 1 | 1 |  |
HBS1-like domain | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 1 | 1 |  |
TPR-like | PUA domain-like | 1 | 1 |  |
Thioredoxin-like | "Winged helix" DNA-binding domain | 1 | 1 |  |
YVTN repeat-like/Quinoprotein amine dehydrogenase | NHL repeat | 1 | 1 |  |
Tudor/PWWP/MBT | BRCT domain | 1 | 1 |  |
Ribosomal protein L25-like | Class II aaRS ABD-related | 1 | 1 |  |
BRK domain-like | BRK domain-like | 1 | 1 |  |
ARM repeat | Fibronectin type III | 1 | 1 |  |
Hairpin loop containing domain-like | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Calcium-dependent phosphotriesterase | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
Inhibitor of apoptosis (IAP) repeat | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
Dihydropteroate synthetase-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 |  |
Kazal-type serine protease inhibitors | EF-hand | 1 | 1 |  |
POZ domain | Pentapeptide repeat-like | 1 | 1 |  |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Nqo1 FMN-binding domain-like | Nqo1C-terminal domain-like | 1 | 1 |  |
(Trans)glycosidases | (Trans)glycosidases | 1 | 1 |  |
(Trans)glycosidases | Beta-D-glucan exohydrolase, C-terminal domain | 1 | 1 |  |
Invertebrate chitin-binding proteins | beta-N-acetylhexosaminidase-like domain | 1 | 1 |  |
Ubiquitin-like | FYVE/PHD zinc finger | 1 | 1 |  |
LDL receptor-like module | Fibronectin type III | 1 | 1 |  |
Immunoglobulin | FnI-like domain | 1 | 1 |  |
DNA/RNA polymerases | FYVE/PHD zinc finger | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 |  |
SRCR-like | C-type lectin-like | 1 | 1 |  |
WW domain | FKBP-like | 1 | 1 |  |
Family A G protein-coupled receptor-like | SH3-domain | 1 | 1 |  |
BRCA2 helical domain | BRCA2 tower domain | 1 | 1 |  |
Ankyrin repeat | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 |  |
FYVE/PHD zinc finger | RNI-like | 1 | 1 |  |
BAR/IMD domain-like | SH2 domain | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
PheT/TilS domain | Class II aaRS and biotin synthetases | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | HSP20-like chaperones | 1 | 1 |  |
Cap-Gly domain | Cysteine proteinases | 1 | 1 |  |
YjgF-like | YjgF-like | 1 | 1 |  |
ENT-like | Bromodomain | 1 | 1 |  |
Tudor/PWWP/MBT | SET domain | 1 | 1 |  |
PX domain | TPR-like | 1 | 1 |  |
Calponin-homology domain, CH-domain | Ubiquitin-like | 1 | 1 |  |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 1 | 1 |  |
Lipovitellin-phosvitin complex; beta-sheet shell regions | vWA-like | 1 | 1 |  |
Zinc beta-ribbon | Zinc beta-ribbon | 1 | 1 |  |
HAD-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
WWE domain | Hect, E3 ligase catalytic domain | 1 | 1 |  |
CRAL/TRIO domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
Protease propeptides/inhibitors | Galactose-binding domain-like | 1 | 1 |  |
Nqo1 middle domain-like | Nqo1C-terminal domain-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | R3H domain | 1 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | SAM/Pointed domain | 1 | 1 |  |
RuvA domain 2-like | WD40 repeat-like | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | WD40 repeat-like | 1 | 1 |  |
PH domain-like | BSD domain-like | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | VPS9 domain | 1 | 1 |  |
BRK domain-like | Elongation factor TFIIS domain 2 | 1 | 1 |  |
TSP-1 type 1 repeat | PMP inhibitors | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | Protein kinase-like (PK-like) | 1 | 1 |  |
DBL homology domain (DH-domain) | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
BPTI-like | Immunoglobulin | 1 | 1 |  |
HIT-like | HIT-like | 1 | 1 |  |
EF-hand | DUSP-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Cysteine-rich domain | 1 | 1 |  |
Dihydropteroate synthetase-like | Methionine synthase domain | 1 | 1 |  |
EF-hand | Isochorismatase-like hydrolases | 1 | 1 |  |
Trimeric LpxA-like enzymes | Trimeric LpxA-like enzymes | 1 | 1 |  |
ARM repeat | HSP20-like chaperones | 1 | 1 |  |
Leech antihemostatic proteins | Leech antihemostatic proteins | 1 | 1 |  |
PDZ domain-like | EF-hand | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | POZ domain | 1 | 1 |  |
GST C-terminal domain-like | C-terminal domain of ProRS | 1 | 1 |  |
Galactose-binding domain-like | Protein kinase-like (PK-like) | 1 | 1 |  |
vWA-like | Sensory domain-like | 1 | 1 |  |
GST C-terminal domain-like | eEF1-gamma domain | 1 | 1 |  |
Chaperone J-domain | E set domains | 1 | 1 |  |
Ubiquitin-like | AN1-like Zinc finger | 1 | 1 |  |
EPT/RTPC-like | RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 1 | 1 |  |
Thioredoxin-like | ERP29 C domain-like | 1 | 1 |  |
FYVE/PHD zinc finger | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | DNA/RNA polymerases | 1 | 1 |  |
PKD domain | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 |  |
RING/U-box | Fibronectin type III | 1 | 1 |  |
Invertebrate chitin-binding proteins | E set domains | 1 | 1 |  |
WW domain | Cysteine proteinases | 1 | 1 |  |
ClpS-like | "Winged helix" DNA-binding domain | 1 | 1 |  |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 1 | 1 |  |
Carbon-nitrogen hydrolase | Adenine nucleotide alpha hydrolases-like | 1 | 1 |  |
Galactose mutarotase-like | Glycosyl hydrolase domain | 1 | 1 |  |
Nucleic acid-binding proteins | SH2 domain | 1 | 1 |  |
Ribonuclease H-like | SH2 domain | 1 | 1 |  |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | Translational machinery components | 1 | 1 |  |
DNA clamp | DNA clamp | 1 | 1 |  |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 1 | 1 |  |
Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 1 | 1 |  |
Tricorn protease domain 2 | WD40 repeat-like | 1 | 1 |  |
Clavaminate synthase-like | RNI-like | 1 | 1 |  |
HLH, helix-loop-helix DNA-binding domain | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
Galactose-binding domain-like | BRCT domain | 1 | 1 |  |
EGF/Laminin | Ankyrin repeat | 1 | 1 |  |
Acyl-CoA binding protein | ClpP/crotonase | 1 | 1 |  |
Nucleic acid-binding proteins | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | EF-hand | 1 | 1 |  |
RUN domain-like | PDZ domain-like | 1 | 1 |  |
RNA-binding domain, RBD | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 |  |
cAMP-binding domain-like | FabD/lysophospholipase-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Fzo-like conserved region | 1 | 1 |  |
Acyl-CoA binding protein | Ankyrin repeat | 1 | 1 |  |
Formin homology 2 domain (FH2 domain) | RING/U-box | 1 | 1 |  |
DBL homology domain (DH-domain) | WD40 repeat-like | 1 | 1 |  |
TROVE domain-like | vWA-like | 1 | 1 |  |
USP8 N-terminal domain-like | Cysteine proteinases | 1 | 1 |  |
Periplasmic binding protein-like II | Nucleotide cyclase | 1 | 1 |  |
beta-beta-alpha zinc fingers | Ribonuclease H-like | 1 | 1 |  |
POZ domain | Galactose-binding domain-like | 1 | 1 |  |
"Winged helix" DNA-binding domain | GTPase activation domain, GAP | 1 | 1 |  |
TNF receptor-like | TNF receptor-like | 1 | 1 |  |
PheT/TilS domain | Putative DNA-binding domain | 1 | 1 |  |
Galactose-binding domain-like | EGF/Laminin | 1 | 1 |  |
Growth factor receptor domain | Fibronectin type III | 1 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 |  |
Trypsin-like serine proteases | PDZ domain-like | 1 | 1 |  |
Nucleic acid-binding proteins | Retrovirus zinc finger-like domains | 1 | 1 |  |
FAD/NAD(P)-binding domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
PH domain-like | Cullin repeat-like | 1 | 1 |  |
Cysteine-rich DNA binding domain, (DM domain) | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | RING/U-box | 1 | 1 |  |
vWA-like | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Actin depolymerizing proteins | SH3-domain | 1 | 1 |  |
beta-beta-alpha zinc fingers | TRAF domain-like | 1 | 1 |  |
Integrin alpha N-terminal domain | Integrin alpha N-terminal domain | 1 | 1 |  |
SH2 domain | Ras GEF | 1 | 1 |  |
Amyloid beta a4 protein copper binding domain (domain 2) | CAPPD, an extracellular domain of amyloid beta A4 protein | 1 | 1 |  |
PDZ domain-like | "Winged helix" DNA-binding domain | 1 | 1 |  |
beta-beta-alpha zinc fingers | ARM repeat | 1 | 1 |  |
Kelch motif | Galactose oxidase, central domain | 1 | 1 |  |
SAICAR synthase-like | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 |  |
RNA-binding domain, RBD | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
PH domain-like | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain | 1 | 1 |  |
AF1104-like | AF1104-like | 1 | 1 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HMG-box | 1 | 1 |  |
Plexin repeat | TSP-1 type 1 repeat | 1 | 1 |  |
dsRNA-binding domain-like | R3H domain | 1 | 1 |  |
ARM repeat | EGF/Laminin | 1 | 1 |  |
ARM repeat | CYTH-like phosphatases | 1 | 1 |  |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 |  |
Prokaryotic type I DNA topoisomerase | Zinc beta-ribbon | 1 | 1 |  |
PA domain | RING/U-box | 1 | 1 |  |
RNA-binding domain, RBD | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | DPP6 N-terminal domain-like | 1 | 1 |  |
SEA domain | LDL receptor-like module | 1 | 1 |  |
Protease propeptides/inhibitors | Zn-dependent exopeptidases | 1 | 1 |  |
R3H domain | Ribonuclease H-like | 1 | 1 |  |
MgtE membrane domain-like | MgtE membrane domain-like | 1 | 1 |  |
CAD & PB1 domains | His-Me finger endonucleases | 1 | 1 |  |
GAT-like domain | Clathrin adaptor appendage domain | 1 | 1 |  |
PUG domain-like | Cysteine proteinases | 1 | 1 |  |
Oxidoreductase molybdopterin-binding domain | E set domains | 1 | 1 |  |
Cadherin-like | ARM repeat | 1 | 1 |  |
Tex N-terminal region-like | SH2 domain | 1 | 1 |  |
Band 7/SPFH domain | SCP-like | 1 | 1 |  |
RING/U-box | DUSP-like | 1 | 1 |  |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
Heme-dependent peroxidases | EF-hand | 1 | 1 |  |
UBC-like | LigT-like | 1 | 1 |  |
Ribosomal protein L25-like | Class II aaRS and biotin synthetases | 1 | 1 |  |
ARID-like | ARM repeat | 1 | 1 |  |
EGF/Laminin | Trypsin-like serine proteases | 1 | 1 |  |
WW domain | PH domain-like | 1 | 1 |  |
RUN domain-like | PH domain-like | 1 | 1 |  |
BRCA2 helical domain | Nucleic acid-binding proteins | 1 | 1 |  |
Ligand-binding domain in the NO signalling and Golgi transport | Nucleotide cyclase | 1 | 1 |  |
Homocysteine S-methyltransferase | Methionine synthase domain | 1 | 1 |  |
A heparin-binding domain | Amyloid beta a4 protein copper binding domain (domain 2) | 1 | 1 |  |
Ribosomal protein L6 | Ribosomal protein L6 | 1 | 1 |  |
PX domain | GTPase activation domain, GAP | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 |  |
Tricorn protease domain 2 | RCC1/BLIP-II | 1 | 1 |  |
Insect cysteine-rich antifreeze protein | Insect cysteine-rich antifreeze protein | 1 | 1 |  |
RNA-binding domain, RBD | dsRNA-binding domain-like | 1 | 1 |  |
Growth factor receptor domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
DNA breaking-rejoining enzymes | POZ domain | 1 | 1 |  |
SMAD/FHA domain | Protein kinase-like (PK-like) | 1 | 1 |  |
Ribosomal L27 protein-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 |  |
Arp2/3 complex subunits | Arp2/3 complex subunits | 1 | 1 |  |
Rhodanese/Cell cycle control phosphatase | Cysteine proteinases | 1 | 1 |  |
Apolipoprotein A-I | Apolipoprotein A-I | 1 | 1 |  |
E set domains | Hect, E3 ligase catalytic domain | 1 | 1 |  |
Macro domain-like | ADP-ribosylation | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 1 | 1 |  |
Regulator of G-protein signaling, RGS | Protein kinase-like (PK-like) | 1 | 1 |  |
NAD kinase/diacylglycerol kinase-like | NAD kinase/diacylglycerol kinase-like | 1 | 1 |  |
Thiolase-like | SCP-like | 1 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | ARM repeat | 1 | 1 |  |
ADP-ribosylation | Outer arm dynein light chain 1 | 1 | 1 |  |
NTF2-like | RNA-binding domain, RBD | 1 | 1 |  |
HSP20-like chaperones | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 |  |
Plexin repeat | Immunoglobulin | 1 | 1 |  |
Nucleic acid-binding proteins | eIF2alpha middle domain-like | 1 | 1 |  |
PH domain-like | C-terminal domain of PLC-beta | 1 | 1 |  |
SH3-domain | Plakin repeat | 1 | 1 |  |
N-terminal domain of cbl (N-cbl) | UBA-like | 1 | 1 |  |
Creatinase/aminopeptidase | "Winged helix" DNA-binding domain | 1 | 1 |  |
"Winged helix" DNA-binding domain | Protein kinase-like (PK-like) | 1 | 1 |  |
PX domain | MIT domain | 1 | 1 |  |
PAH2 domain | Homeodomain-like | 1 | 1 |  |
Nicotinic receptor ligand binding domain-like | Nicotinic receptor ligand binding domain-like | 1 | 1 |  |
Nucleic acid-binding proteins | eIF-2-alpha, C-terminal domain | 1 | 1 |  |
Homeodomain-like | L-aspartase-like | 1 | 1 |  |
UBA-like | XPC-binding domain | 1 | 1 |  |
SH3-domain | WW domain | 1 | 1 |  |
Soluble quinoprotein glucose dehydrogenase | SAM/Pointed domain | 1 | 1 |  |
TPR-like | PIN domain-like | 1 | 1 |  |
Macro domain-like | BRCT domain | 1 | 1 |  |
WWE domain | WGR domain-like | 1 | 1 |  |
FAD/NAD(P)-binding domain | Aminomethyltransferase beta-barrel domain | 1 | 1 |  |
Inhibitor of apoptosis (IAP) repeat | UBC-like | 1 | 1 |  |
Ribosomal protein L25-like | C-terminal domain of ProRS | 1 | 1 |  |
Calponin-homology domain, CH-domain | SH3-domain | 1 | 1 |  |
(Phosphotyrosine protein) phosphatases II | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 1 | 1 |  |
PHM/PNGase F | NHL repeat | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | SMR domain-like | 1 | 1 |  |
Calcyclin-binding protein-like | HSP20-like chaperones | 1 | 1 |  |
Methionine synthase domain | Methionine synthase activation domain-like | 1 | 1 |  |
RuvA domain 2-like | Nucleic acid-binding proteins | 1 | 1 |  |
Nucleotidylyl transferase | Nucleotidylyl transferase | 1 | 1 |  |
BRCT domain | PsbU/PolX domain-like | 1 | 1 |  |
POZ domain | Skp1 dimerisation domain-like | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 |  |
Rap/Ran-GAP | PDZ domain-like | 1 | 1 |  |
CoA-dependent acyltransferases | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
PUA domain-like | Nucleotidylyl transferase | 1 | 1 |  |
FYVE/PHD zinc finger | Rabenosyn-5 Rab-binding domain-like | 1 | 1 |  |
PH domain-like | RING/U-box | 1 | 1 |  |
SAM/Pointed domain | E set domains | 1 | 1 |  |
SH2 domain | PLC-like phosphodiesterases | 1 | 1 |  |
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | 1 |  |
Chaperone J-domain | HSC20 (HSCB), C-terminal oligomerisation domain | 1 | 1 |  |
Immunoglobulin | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
Histone-fold | Ras GEF | 1 | 1 |  |
Ankyrin repeat | Domain of poly(ADP-ribose) polymerase | 1 | 1 |  |
L domain-like | PDZ domain-like | 1 | 1 |  |
PH domain-like | Glycolipid transfer protein, GLTP | 1 | 1 |  |
dsRNA-binding domain-like | Tudor/PWWP/MBT | 1 | 1 |  |
B-box zinc-binding domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Rad50 coiled-coil Zn hook | 1 | 1 |  |
beta-beta-alpha zinc fingers | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
F-box domain | YccV-like | 1 | 1 |  |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 1 | 1 |  |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Fibronectin type III | 1 | 1 |  |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 1 | 1 |  |
PX domain | L domain-like | 1 | 1 |  |
CCHHC domain | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 |  |
Galactose-binding domain-like | Kelch motif | 1 | 1 |  |
Growth factor receptor domain | Ankyrin repeat | 1 | 1 |  |
FMT C-terminal domain-like | ACP-like | 1 | 1 |  |
WD40 repeat-like | DPP6 N-terminal domain-like | 1 | 1 |  |
Calponin-homology domain, CH-domain | RGC domain-like | 1 | 1 |  |
DNA/RNA polymerases | ARM repeat | 1 | 1 |  |
S15/NS1 RNA-binding domain | C-terminal domain of ProRS | 1 | 1 |  |
Chaperone J-domain | Homeodomain-like | 1 | 1 |  |
Ankyrin repeat | Family A G protein-coupled receptor-like | 1 | 1 |  |
ARM repeat | HLH, helix-loop-helix DNA-binding domain | 1 | 1 |  |
Thioredoxin-like | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 1 | 1 |  |
FYVE/PHD zinc finger | PUA domain-like | 1 | 1 |  |
PRP4-like | WD40 repeat-like | 1 | 1 |  |
vWA-like | SPOC domain-like | 1 | 1 |  |
Heme-dependent peroxidases | Riboflavin synthase domain-like | 1 | 1 |  |
DNA/RNA polymerases | Zinc finger domain of DNA polymerase-alpha | 1 | 1 |  |
Calponin-homology domain, CH-domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Macro domain-like | 1 | 1 |  |
RING/U-box | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
Cna protein B-type domain | Starch-binding domain-like | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | UBA-like | 1 | 1 |  |
Nucleotidylyl transferase | Nucleic acid-binding proteins | 1 | 1 |  |
SH3-domain | Fibronectin type III | 1 | 1 |  |
ARM repeat | Cystine-knot cytokines | 1 | 1 |  |
cAMP-binding domain-like | PDZ domain-like | 1 | 1 |  |
Lipovitellin-phosvitin complex, superhelical domain | vWA-like | 1 | 1 |  |
Glycosyl hydrolase domain | Glycosyl hydrolase domain | 1 | 1 |  |
Kringle-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
SMAD/FHA domain | PDZ domain-like | 1 | 1 |  |
Second domain of FERM | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain | WD40 repeat-like | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | FMN-linked oxidoreductases | 1 | 1 |  |
Calponin-homology domain, CH-domain | GAS2 domain-like | 1 | 1 |  |
HBS1-like domain | Translation proteins | 1 | 1 |  |
RING/U-box | RNA-binding domain, RBD | 1 | 1 |  |
Histone-fold | DBL homology domain (DH-domain) | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | NagB/RpiA/CoA transferase-like | 1 | 1 |  |
SAM/Pointed domain | Hect, E3 ligase catalytic domain | 1 | 1 |  |
DNA-glycosylase | Nudix | 1 | 1 |  |
SH3-domain | Immunoglobulin | 1 | 1 |  |
L domain-like | ADP-ribosylation | 1 | 1 |  |
ENTH/VHS domain | FYVE/PHD zinc finger | 1 | 1 |  |
YWTD domain | Complement control module/SCR domain | 1 | 1 |  |
SH3-domain | PLC-like phosphodiesterases | 1 | 1 |  |
Histone-fold | Histone-fold | 1 | 1 |  |
Ubiquitin-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
GST C-terminal domain-like | Ribosomal protein L25-like | 1 | 1 |  |
DNase I-like | MFS general substrate transporter | 1 | 1 |  |
EPT/RTPC-like | EPT/RTPC-like | 1 | 1 |  |
Ubiquitin-like | HAD-like | 1 | 1 |  |
Protease propeptides/inhibitors | Subtilisin-like | 1 | 1 |  |
Endosomal sorting complex assembly domain | VPS28 C-terminal domain-like | 1 | 1 |  |
SAP domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
ADP-ribosylation | ADP-ribosylation | 1 | 1 |  |
Ankyrin repeat | beta-N-acetylhexosaminidase-like domain | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | DHS-like NAD/FAD-binding domain | 1 | 1 |  |
Ankyrin repeat | RCC1/BLIP-II | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | 4Fe-4S ferredoxins | 1 | 1 |  |
Spectrin repeat | DBL homology domain (DH-domain) | 1 | 1 |  |
Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, substrate-binding domain | 1 | 1 |  |
Histone-fold | FYVE/PHD zinc finger | 1 | 1 |  |
Cytochrome c | Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor | 1 | 1 |  |
EF-hand | C-terminal domain of PLC-beta | 1 | 1 |  |
Acid proteases | ARM repeat | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
ARM repeat | CalX-like | 1 | 1 |  |
DNA/RNA polymerases | L domain-like | 1 | 1 |  |
HR1 repeat | PDZ domain-like | 1 | 1 |  |
F-box domain | UBC-like | 1 | 1 |  |
RING/U-box | DEATH domain | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Nucleic acid-binding proteins | 1 | 1 |  |
Homocysteine S-methyltransferase | Cobalamin (vitamin B12)-binding domain | 1 | 1 |  |
TPR-like | RNA-binding domain, RBD | 1 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | RING/U-box | 1 | 1 |  |
SIS domain | SIS domain | 1 | 1 |  |
WD40 repeat-like | Prefoldin | 1 | 1 |  |
Doublecortin (DC) | Protein kinase-like (PK-like) | 1 | 1 |  |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 1 | 1 |  |
G protein-binding domain | PH domain-like | 1 | 1 |  |
DNase I-like | GTPase activation domain, GAP | 1 | 1 |  |
CCCH zinc finger | RNA-binding domain, RBD | 1 | 1 |  |
Ubiquitin-like | PUA domain-like | 1 | 1 |  |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 |  |
Carbonic anhydrase | Carbonic anhydrase | 1 | 1 |  |
EF-hand | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 |  |
FAS1 domain | Growth factor receptor domain | 1 | 1 |  |
UBA-like | Tudor/PWWP/MBT | 1 | 1 |  |
Cadherin-like | Growth factor receptor domain | 1 | 1 |  |
eIF2alpha middle domain-like | eIF-2-alpha, C-terminal domain | 1 | 1 |  |
Leukotriene A4 hydrolase N-terminal domain | Leukotriene A4 hydrolase N-terminal domain | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | UBC-like | 1 | 1 |  |
WD40 repeat-like | Bromodomain | 1 | 1 |  |
Cystine-knot cytokines | Cystine-knot cytokines | 1 | 1 |  |
Dimeric alpha+beta barrel | Dimeric alpha+beta barrel | 1 | 1 |  |
Galactose-binding domain-like | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
TSP-1 type 1 repeat | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
PLC-like phosphodiesterases | PLC-like phosphodiesterases | 1 | 1 |  |
Serine protease inhibitors | Growth factor receptor domain | 1 | 1 |  |
EF-hand | Riboflavin synthase domain-like | 1 | 1 |  |
HMA, heavy metal-associated domain | Cu,Zn superoxide dismutase-like | 1 | 1 |  |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 1 | 1 |  |
Kazal-type serine protease inhibitors | Immunoglobulin | 1 | 1 |  |
Formate/glycerate dehydrogenase catalytic domain-like | DHS-like NAD/FAD-binding domain | 1 | 1 |  |
BAR/IMD domain-like | Family A G protein-coupled receptor-like | 1 | 1 |  |
PLP-dependent transferases | PLP-dependent transferases | 1 | 1 |  |
GFP-like | Growth factor receptor domain | 1 | 1 |  |
DNA-binding domain | FYVE/PHD zinc finger | 1 | 1 |  |
Histone-fold | Macro domain-like | 1 | 1 |  |
Chromo domain-like | BRK domain-like | 1 | 1 |  |
Eukaryotic RPB5 N-terminal domain | RPB5-like RNA polymerase subunit | 1 | 1 |  |
GTPase activation domain, GAP | RGC domain-like | 1 | 1 |  |
DBL homology domain (DH-domain) | FYVE/PHD zinc finger | 1 | 1 |  |
UBC-like | UBA-like | 1 | 1 |  |
ArfGap/RecO-like zinc finger | Family A G protein-coupled receptor-like | 1 | 1 |  |
WD40 repeat-like | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 |  |
TPR-like | Fic-like | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | P-domain of calnexin/calreticulin | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | SOCS box-like | 1 | 1 |  |
ENTH/VHS domain | SH3-domain | 1 | 1 |  |
Oligoxyloglucan reducing end-specific cellobiohydrolase | YWTD domain | 1 | 1 |  |
Frizzled cysteine-rich domain | LDL receptor-like module | 1 | 1 |  |
beta-beta-alpha zinc fingers | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 |  |
Tudor/PWWP/MBT | Chromo domain-like | 1 | 1 |  |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 1 | 1 |  |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 |  |
Ribosomal protein L25-like | S15/NS1 RNA-binding domain | 1 | 1 |  |
TPR-like | Toll/Interleukin receptor TIR domain | 1 | 1 |  |
EF-hand | Rhomboid-like | 1 | 1 |  |
Leucine zipper domain | Leucine zipper domain | 1 | 1 |  |
TSP-1 type 1 repeat | BPTI-like | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | E set domains | 1 | 1 |  |
WWE domain | WWE domain | 1 | 1 |  |
EF-hand | Immunoglobulin | 1 | 1 |  |
RING/U-box | SH3-domain | 1 | 1 |  |
Tudor/PWWP/MBT | CCHHC domain | 1 | 1 |  |
F-box domain | Kelch motif | 1 | 1 |  |
Ankyrin repeat | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 |  |
Chaperone J-domain | beta-beta-alpha zinc fingers | 1 | 1 |  |
YccV-like | ApaG-like | 1 | 1 |  |
Tricorn protease domain 2 | TPR-like | 1 | 1 |  |
BSD domain-like | BSD domain-like | 1 | 1 |  |
E set domains | Pectin lyase-like | 1 | 1 |  |
Doublecortin (DC) | Ricin B-like lectins | 1 | 1 |  |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | DEATH domain | 1 | 1 |  |
Ribonuclease H-like | RNA-binding domain, RBD | 1 | 1 |  |
ARM repeat | Galactose-binding domain-like | 1 | 1 |  |
Cu,Zn superoxide dismutase-like | Cu,Zn superoxide dismutase-like | 1 | 1 |  |
FYVE/PHD zinc finger | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 |  |
Lipocalins | Lipocalins | 1 | 1 |  |
RNA-binding domain, RBD | SPOC domain-like | 1 | 1 |  |
GFP-like | EGF/Laminin | 1 | 1 |  |
Complement control module/SCR domain | SRCR-like | 1 | 1 |  |
Tex N-terminal region-like | Nucleic acid-binding proteins | 1 | 1 |  |
Translation proteins | Translation proteins | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | DPP6 N-terminal domain-like | 1 | 1 |  |
N-terminal domain of cbl (N-cbl) | SH2 domain | 1 | 1 |  |
Thioredoxin-like | FAD/NAD(P)-binding domain | 1 | 1 |  |
PUA domain-like | SWIB/MDM2 domain | 1 | 1 |  |
PRTase-like | Ribulose-phoshate binding barrel | 1 | 1 |  |
Hedgehog/DD-peptidase | Hedgehog/DD-peptidase | 1 | 1 |  |
Notch domain | Ankyrin repeat | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Ribonuclease H-like | 1 | 1 |  |
N-terminal domain of cbl (N-cbl) | RING/U-box | 1 | 1 |  |
MIT domain | Calpain large subunit, middle domain (domain III) | 1 | 1 |  |
BRCT domain | DNA/RNA polymerases | 1 | 1 |  |
Class II aaRS and biotin synthetases | C-terminal domain of ProRS | 1 | 1 |  |
Snake toxin-like | Family A G protein-coupled receptor-like | 1 | 1 |  |
CCCH zinc finger | Retrovirus zinc finger-like domains | 1 | 1 |  |
IP3 receptor type 1 binding core, domain 2 | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
GST C-terminal domain-like | Class II aaRS ABD-related | 1 | 1 |  |
Sema domain | TSP-1 type 1 repeat | 1 | 1 |  |
Alpha subunit of glutamate synthase, C-terminal domain | alpha-helical ferredoxin | 1 | 1 |  |
Notch domain | Notch domain | 1 | 1 |  |
ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
Formin homology 2 domain (FH2 domain) | SAM/Pointed domain | 1 | 1 |  |
RNA-binding domain, RBD | DPP6 N-terminal domain-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 1 | 1 |  |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Putative DNA-binding domain | 1 | 1 |  |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 |  |
SH2 domain | UBA-like | 1 | 1 |  |
Serine protease inhibitors | vWA-like | 1 | 1 |  |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 1 | 1 |  |
Formyltransferase | ACP-like | 1 | 1 |  |
Methylglyoxal synthase-like | Cytidine deaminase-like | 1 | 1 |  |
Homocysteine S-methyltransferase | Methionine synthase activation domain-like | 1 | 1 |  |
FYVE/PHD zinc finger | Elongation factor TFIIS domain 2 | 1 | 1 |  |
Spectrin repeat | Immunoglobulin | 1 | 1 |  |
Fibronectin type III | Thioredoxin-like | 1 | 1 |  |
Acyl-CoA binding protein | Supernatant protein factor (SPF), C-terminal domain | 1 | 1 |  |
A heparin-binding domain | CAPPD, an extracellular domain of amyloid beta A4 protein | 1 | 1 |  |
Ankyrin repeat | (Trans)glycosidases | 1 | 1 |  |
L domain-like | Trypsin-like serine proteases | 1 | 1 |  |
Ribosomal protein S5 domain 2-like | HMG-box | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | SH2 domain | 1 | 1 |  |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | 1 |  |
Starch-binding domain-like | Starch-binding domain-like | 1 | 1 |  |
Methionine synthase domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Hect, E3 ligase catalytic domain | 1 | 1 |  |
WWE domain | Domain of poly(ADP-ribose) polymerase | 1 | 1 |  |
Cobalamin (vitamin B12)-binding domain | Methionine synthase activation domain-like | 1 | 1 |  |
Dom34/Pelota N-terminal domain-like | L30e-like | 1 | 1 |  |
Epsilon subunit of F1F0-ATP synthase N-terminal domain | Epsilon subunit of F1F0-ATP synthase C-terminal domain | 1 | 1 |  |
EGF/Laminin | Notch domain | 1 | 1 |  |
DNase I-like | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
BRCT domain | post-AAA+ oligomerization domain-like | 1 | 1 |  |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 |  |
RING/U-box | WWE domain | 1 | 1 |  |
Retrovirus capsid dimerization domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
mRNA decapping enzyme DcpS N-terminal domain | HIT-like | 1 | 1 |  |
Aminopeptidase/glucanase lid domain | Zn-dependent exopeptidases | 1 | 1 |  |
Nucleotide-diphospho-sugar transferases | SAM/Pointed domain | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | FnI-like domain | 1 | 1 |  |
PLC-like phosphodiesterases | Ubiquitin-like | 1 | 1 |  |
SH2 domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
PUG domain-like | Galactose-binding domain-like | 1 | 1 |  |
WD40 repeat-like | Cyclophilin-like | 1 | 1 |  |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 1 | 1 |  |
SH3-domain | Phosphoglycerate mutase-like | 1 | 1 |  |
PRP4-like | Functional domain of the splicing factor Prp18 | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Microbial and mitochondrial ADK, insert "zinc finger" domain | 1 | 1 |  |
Amidase signature (AS) enzymes | Amidase signature (AS) enzymes | 1 | 1 |  |
Chaperone J-domain | Sec63 N-terminal domain-like | 1 | 1 |  |
EGF/Laminin | TSP type-3 repeat | 1 | 1 |  |
lambda repressor-like DNA-binding domains | lambda repressor-like DNA-binding domains | 1 | 1 |  |
ARM repeat | SAM/Pointed domain | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | beta-beta-alpha zinc fingers | 1 | 1 |  |
PIN domain-like | Nucleic acid-binding proteins | 1 | 1 |  |
CalX-like | C-type lectin-like | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain III | 1 | 1 |  |
Doublecortin (DC) | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | Folate-binding domain | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 |  |
HSP20-like chaperones | Riboflavin synthase domain-like | 1 | 1 |  |
Ankyrin repeat | PDZ domain-like | 1 | 1 |  |
L9 N-domain-like | Ribonuclease H-like | 1 | 1 |  |
PEBP-like | PEBP-like | 1 | 1 |  |
Kazal-type serine protease inhibitors | TSP-1 type 1 repeat | 1 | 1 |  |
Nucleic acid-binding proteins | BRCA2 tower domain | 1 | 1 |  |
alpha/beta knot | Nucleic acid-binding proteins | 1 | 1 |  |
FKBP-like | FKBP-like | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | Protein kinase-like (PK-like) | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 1 | 1 |  |
vWA-like | TSP-1 type 1 repeat | 1 | 1 |  |
PH domain-like | HMG-box | 1 | 1 |  |
UBA-like | WWE domain | 1 | 1 |  |
CCHHC domain | SAM/Pointed domain | 1 | 1 |  |
YaeB-like | YaeB-like | 1 | 1 |  |
Formiminotransferase domain of formiminotransferase-cyclodeaminase. | Methenyltetrahydrofolate cyclohydrolase-like | 1 | 1 |  |
Invertebrate chitin-binding proteins | Carbohydrate-binding domain | 1 | 1 |  |
POZ domain | WD40 repeat-like | 1 | 1 |  |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 |  |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Sialidases | 1 | 1 |  |
Ribonuclease H-like | HRDC-like | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | EF-hand | 1 | 1 |  |
TPR-like | Metallo-dependent phosphatases | 1 | 1 |  |
SH3-domain | UBA-like | 1 | 1 |  |
F-box domain | ApaG-like | 1 | 1 |  |
NagB/RpiA/CoA transferase-like | NagB/RpiA/CoA transferase-like | 1 | 1 |  |
FYVE/PHD zinc finger | GroEL apical domain-like | 1 | 1 |  |
Class II aaRS ABD-related | C-terminal domain of ProRS | 1 | 1 |  |
"Winged helix" DNA-binding domain | beta-sandwich domain of Sec23/24 | 1 | 1 |  |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 1 | 1 |  |
RNI-like | Trypsin-like serine proteases | 1 | 1 |  |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | NagB/RpiA/CoA transferase-like | 1 | 1 |  |
AXH domain | HMG-box | 1 | 1 |  |
LDL receptor-like module | Family A G protein-coupled receptor-like | 1 | 1 |  |
FMT C-terminal domain-like | ALDH-like | 1 | 1 |  |
ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 |  |
Sialidases | Sialidases | 1 | 1 |  |
MOSC N-terminal domain-like | PK beta-barrel domain-like | 1 | 1 |  |
BRCT domain | Homeodomain-like | 1 | 1 |  |
Dom34/Pelota N-terminal domain-like | Translational machinery components | 1 | 1 |  |
Homeodomain-like | Creatinase/prolidase N-terminal domain | 1 | 1 |  |
TSP-1 type 1 repeat | GFP-like | 1 | 1 |  |
Homeodomain-like | JAB1/MPN domain | 1 | 1 |  |
Kazal-type serine protease inhibitors | L domain-like | 1 | 1 |  |
Staphylococcal nuclease | Staphylococcal nuclease | 1 | 1 |  |
MIR domain | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | E set domains | 1 | 1 |  |
Regulator of G-protein signaling, RGS | Ubiquitin-like | 1 | 1 |  |
Protein kinase-like (PK-like) | HCP-like | 1 | 1 |  |
Alpha subunit of glutamate synthase, C-terminal domain | Nucleotide-binding domain | 1 | 1 |  |
"Winged helix" DNA-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
CRAL/TRIO domain | GTPase activation domain, GAP | 1 | 1 |  |
Ribonuclease H-like | Nucleic acid-binding proteins | 1 | 1 |  |
4Fe-4S ferredoxins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
SAM/Pointed domain | Ras GEF | 1 | 1 |  |
RuvA domain 2-like | F-box domain | 1 | 1 |  |
NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 1 | 1 |  |
FAD/NAD(P)-binding domain | Folate-binding domain | 1 | 1 |  |
p53-like transcription factors | p53 tetramerization domain | 1 | 1 |  |
Tropomyosin | beta-beta-alpha zinc fingers | 1 | 1 |  |
PLP-dependent transferases | Adenine nucleotide alpha hydrolases-like | 1 | 1 |  |
Thioesterase/thiol ester dehydrase-isomerase | SCP-like | 1 | 1 |  |
Glycerol-3-phosphate (1)-acyltransferase | EF-hand | 1 | 1 |  |
Heme-dependent peroxidases | FnI-like domain | 1 | 1 |  |
R3H domain | RNA-binding domain, RBD | 1 | 1 |  |
TRAF domain-like | PDZ domain-like | 1 | 1 |  |
Protein kinase-like (PK-like) | Ypt/Rab-GAP domain of gyp1p | 1 | 1 |  |
(Phosphotyrosine protein) phosphatases II | Nucleic acid-binding proteins | 1 | 1 |  |
Histone-fold | PH domain-like | 1 | 1 |  |
Ankyrin repeat | EF-hand | 1 | 1 |  |
L domain-like | DNase I-like | 1 | 1 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 1 | 1 |  |
FMN-linked oxidoreductases | Alpha subunit of glutamate synthase, C-terminal domain | 1 | 1 |  |
DNA-binding domain | SET domain | 1 | 1 |  |
Clavaminate synthase-like | EF-hand | 1 | 1 |  |
Rhodanese/Cell cycle control phosphatase | WW domain | 1 | 1 |  |
Calpain large subunit, middle domain (domain III) | Calpain large subunit, middle domain (domain III) | 1 | 1 |  |
TSP-1 type 1 repeat | LDL receptor-like module | 1 | 1 |  |
BRCT domain | DNA polymerase beta, N-terminal domain-like | 1 | 1 |  |
R3H domain | AN1-like Zinc finger | 1 | 1 |  |
HBS1-like domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Retrovirus zinc finger-like domains | DNA/RNA polymerases | 1 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | Metalloproteases ("zincins"), catalytic domain | 1 | 1 |  |
Thioredoxin-like | eEF1-gamma domain | 1 | 1 |  |
Chaperone J-domain | RNA-binding domain, RBD | 1 | 1 |  |
Adenine nucleotide alpha hydrolases-like | Argininosuccinate synthetase, C-terminal domain | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Phosphoglycerate mutase-like | 1 | 1 |  |
Pseudouridine synthase | PUA domain-like | 1 | 1 |  |
Formyltransferase | ALDH-like | 1 | 1 |  |
BAR/IMD domain-like | Protein kinase-like (PK-like) | 1 | 1 |  |
G protein-binding domain | Cysteine-rich domain | 1 | 1 |  |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 |  |
Oxysterol-binding protein-like | Oxysterol-binding protein-like | 1 | 1 |  |
PH domain-like | Phospholipase D/nuclease | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | Aminomethyltransferase beta-barrel domain | 1 | 1 |  |
F-box domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Protein kinase-like (PK-like) | Rhodanese/Cell cycle control phosphatase | 1 | 1 |  |
Bet v1-like | HAD-like | 1 | 1 |  |
TATA-box binding protein-like | TATA-box binding protein-like | 1 | 1 |  |
ARM repeat | Mib/herc2 domain-like | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | ATP-dependent DNA ligase DNA-binding domain | 1 | 1 |  |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | SET domain | 1 | 1 |  |
Calcium-dependent phosphotriesterase | SOCS box-like | 1 | 1 |  |
TPR-like | RING/U-box | 1 | 1 |  |
Oligoxyloglucan reducing end-specific cellobiohydrolase | LDL receptor-like module | 1 | 1 |  |
"Winged helix" DNA-binding domain | occludin/ELL-like | 1 | 1 |  |
BRCT domain | DBL homology domain (DH-domain) | 1 | 1 |  |
Activator of Hsp90 ATPase, Aha1 | Bet v1-like | 1 | 1 |  |
Homeodomain-like | Creatinase/aminopeptidase | 1 | 1 |  |
RNI-like | ARM repeat | 1 | 1 |  |
B-box zinc-binding domain | Tudor/PWWP/MBT | 1 | 1 |  |
Carboxypeptidase regulatory domain-like | Carboxypeptidase regulatory domain-like | 1 | 1 |  |
RUN domain-like | PX domain | 1 | 1 |  |
Nucleic acid-binding proteins | "Winged helix" DNA-binding domain | 1 | 1 |  |
DBL homology domain (DH-domain) | SH2 domain | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | Prefoldin | 1 | 1 |  |
Family A G protein-coupled receptor-like | DEATH domain | 1 | 1 |  |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | L30e-like | 1 | 1 |  |
C-type lectin-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | AN1-like Zinc finger | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | Metallo-hydrolase/oxidoreductase | 1 | 1 |  |
RNA-binding domain, RBD | SET domain | 1 | 1 |  |
TrmE connector domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Heme-dependent peroxidases | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 |  |
Periplasmic binding protein-like II | Protein kinase-like (PK-like) | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | SOCS box-like | 1 | 1 |  |
Ypt/Rab-GAP domain of gyp1p | EF-hand | 1 | 1 |  |
EF-hand | Thyroglobulin type-1 domain | 1 | 1 |  |
EF-hand | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
Sec63 N-terminal domain-like | DNA/RNA polymerases | 1 | 1 |  |
RuvA domain 2-like | SH2 domain | 1 | 1 |  |
EF-hand | Dimeric alpha+beta barrel | 1 | 1 |  |
TAFH domain-like | Histone-fold | 1 | 1 |  |
SMAD/FHA domain | HAD-like | 1 | 1 |  |
ARM repeat | PX domain | 1 | 1 |  |
Mib/herc2 domain-like | Spermadhesin, CUB domain | 1 | 1 |  |
DNA-binding domain | RNI-like | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Oxidoreductase molybdopterin-binding domain | 1 | 1 |  |
ARM repeat | POZ domain | 1 | 1 |  |
Kazal-type serine protease inhibitors | Protein kinase-like (PK-like) | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | RING/U-box | 1 | 1 |  |
Hypothetical protein c14orf129, hspc210 | TPR-like | 1 | 1 |  |
FAD/NAD(P)-binding domain | EF-hand | 1 | 1 |  |
Thioredoxin-like | Galactose-binding domain-like | 1 | 1 |  |
Calponin-homology domain, CH-domain | GTPase activation domain, GAP | 1 | 1 |  |
THUMP domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
SH3-domain | SAM/Pointed domain | 1 | 1 |  |
DAK1/DegV-like | DhaL-like | 1 | 1 |  |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 1 | 1 |  |
Ubiquitin-like | XPC-binding domain | 1 | 1 |  |
Ankyrin repeat | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
F-box domain | Cyclin-like | 1 | 1 |  |
Nucleotidylyl transferase | C-terminal domain of ProRS | 1 | 1 |  |
Aminoacid dehydrogenase-like, N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Acetyl-CoA synthetase-like | Acetyl-CoA synthetase-like | 1 | 1 |  |
Ankyrin repeat | Cap-Gly domain | 1 | 1 |  |
EF-hand | UBA-like | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain II | 1 | 1 |  |
F-box domain | Sec7 domain | 1 | 1 |  |
B-box zinc-binding domain | Fibronectin type III | 1 | 1 |  |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 1 | 1 |  |
Calponin-homology domain, CH-domain | Plakin repeat | 1 | 1 |  |
Ankyrin repeat | TPR-like | 1 | 1 |  |
GST C-terminal domain-like | Class II aaRS and biotin synthetases | 1 | 1 |  |
PYP-like sensor domain (PAS domain) | Protein kinase-like (PK-like) | 1 | 1 |  |
USP8 N-terminal domain-like | Rhodanese/Cell cycle control phosphatase | 1 | 1 |  |
Cysteine proteinases | Tudor/PWWP/MBT | 1 | 1 |  |
BEACH domain | FYVE/PHD zinc finger | 1 | 1 |  |
Galactose mutarotase-like | Galactose mutarotase-like | 1 | 1 |  |
IP3 receptor type 1 binding core, domain 2 | IP3 receptor type 1 binding core, domain 2 | 1 | 1 |  |
Dihydropteroate synthetase-like | Methionine synthase activation domain-like | 1 | 1 |  |
Kelch motif | Growth factor receptor domain | 1 | 1 |  |
Single hybrid motif | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 |  |
Cyclophilin-like | RNA-binding domain, RBD | 1 | 1 |  |
"Winged helix" DNA-binding domain | GroEL apical domain-like | 1 | 1 |  |