SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Domain combination pairs in Homo sapiens 76_38

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).

Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

2746 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Immunoglobulin Immunoglobulin 1978190
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 1851277
KRAB domain (Kruppel-associated box) beta-beta-alpha zinc fingers 803116
MHC antigen-recognition domain Immunoglobulin 4843
Fibronectin type III Fibronectin type III 435156
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 39367
RNA-binding domain, RBD RNA-binding domain, RBD 34639
RING/U-box B-box zinc-binding domain 33729
Cadherin-like Cadherin-like 31750
EGF/Laminin EGF/Laminin 317182
Glucocorticoid receptor-like (DNA-binding domain) Glucocorticoid receptor-like (DNA-binding domain) 26836
Immunoglobulin Fibronectin type III 262101
DBL homology domain (DH-domain) PH domain-like 25571
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 24338
Glucocorticoid receptor-like (DNA-binding domain) Nuclear receptor ligand-binding domain 2187
Complement control module/SCR domain Complement control module/SCR domain 20676
RING/U-box Concanavalin A-like lectins/glucanases 20212
B-box zinc-binding domain Concanavalin A-like lectins/glucanases 19712
PDZ domain-like PDZ domain-like 19462
PH domain-like PH domain-like 18145
TPR-like TPR-like 18036
Homeodomain-like Homeodomain-like 17625
Voltage-gated potassium channels Voltage-gated potassium channels 17511
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 17462
Ubiquitin-like PH domain-like 16429
EGF/Laminin Growth factor receptor domain 160115
Actin-like ATPase domain Actin-like ATPase domain 15919
PH domain-like Second domain of FERM 15637
Spectrin repeat Spectrin repeat 14088
PH domain-like SH3-domain 14050
P-loop containing nucleoside triphosphate hydrolases DEATH domain 13715
ARM repeat ARM repeat 13738
P-loop containing nucleoside triphosphate hydrolases RNI-like 13713
Ubiquitin-like Second domain of FERM 13523
Growth factor receptor domain Growth factor receptor domain 13285
POZ domain beta-beta-alpha zinc fingers 13026
EF-hand EF-hand 12934
SH3-domain SH3-domain 12747
DEATH domain RNI-like 12411
Nicotinic receptor ligand binding domain-like Neurotransmitter-gated ion-channel transmembrane pore 1225
SH3-domain P-loop containing nucleoside triphosphate hydrolases 12121
SH2 domain SH3-domain 12026
HAD-like Calcium ATPase, transmembrane domain M 11819
Intermediate filament protein, coiled coil region Intermediate filament protein, coiled coil region 11819
Spermadhesin, CUB domain Spermadhesin, CUB domain 11652
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11615
Retrovirus capsid dimerization domain-like beta-beta-alpha zinc fingers 11536
Concanavalin A-like lectins/glucanases EGF/Laminin 11566
Thioredoxin-like GST C-terminal domain-like 1155
BAR/IMD domain-like SH3-domain 11119
C2 domain (Calcium/lipid-binding domain, CaLB) PH domain-like 11130
Immunoglobulin Protein kinase-like (PK-like) 11051
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 10912
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 10816
GTPase activation domain, GAP PH domain-like 10838
L domain-like L domain-like 10739
Calcium ATPase, transduction domain A HAD-like 10614
TSP-1 type 1 repeat TSP-1 type 1 repeat 10550
P-loop containing nucleoside triphosphate hydrolases PDZ domain-like 10225
PH domain-like SH2 domain 10130
WW domain WW domain 9944
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 9625
POZ domain Kelch motif 956
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 9413
SH3-domain PDZ domain-like 9320
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 9313
Sema domain Plexin repeat 9218
lambda repressor-like DNA-binding domains Homeodomain-like 9112
SH3-domain Protein kinase-like (PK-like) 8716
FYVE/PHD zinc finger FYVE/PHD zinc finger 8627
SH2 domain Protein kinase-like (PK-like) 8616
Protein kinase-like (PK-like) PH domain-like 8630
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 858
Tudor/PWWP/MBT Tudor/PWWP/MBT 8430
L domain-like Immunoglobulin 8416
LDL receptor-like module LDL receptor-like module 8355
Tudor/PWWP/MBT FYVE/PHD zinc finger 8120
p53-like transcription factors E set domains 807
Cyclin-like Cyclin-like 8010
FYVE/PHD zinc finger Bromodomain 7923
PDZ domain-like PH domain-like 7832
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 784
Fibronectin type III Concanavalin A-like lectins/glucanases 7818
DBL homology domain (DH-domain) SH3-domain 7730
Galactose-binding domain-like Protein kinase-like (PK-like) 7610
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 7520
Calponin-homology domain, CH-domain Spectrin repeat 7543
Fibronectin type III Protein kinase-like (PK-like) 7434
Fibronectin type III (Phosphotyrosine protein) phosphatases II 7328
Complement control module/SCR domain Trypsin-like serine proteases 7216
Complement control module/SCR domain vWA-like 7212
Metalloproteases ("zincins"), catalytic domain Blood coagulation inhibitor (disintegrin) 714
Bromodomain Bromodomain 7113
Ankyrin repeat Ankyrin repeat 6934
WD40 repeat-like WD40 repeat-like 6826
Periplasmic binding protein-like I Periplasmic binding protein-like II 657
RING/U-box RING/U-box 6528
KRAB domain (Kruppel-associated box) Retrovirus capsid dimerization domain-like 6526
HLH, helix-loop-helix DNA-binding domain PYP-like sensor domain (PAS domain) 6411
L27 domain PDZ domain-like 6316
Ubiquitin-like Ubiquitin-like 6321
E set domains E set domains 6320
PH domain-like ArfGap/RecO-like zinc finger 6022
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 6010
(Phosphotyrosine protein) phosphatases II PH domain-like 6016
dsRNA-binding domain-like dsRNA-binding domain-like 5916
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 5917
GroES-like NAD(P)-binding Rossmann-fold domains 596
vWA-like vWA-like 5936
Cysteine-rich domain PH domain-like 5819
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 585
TNF receptor-like TNF receptor-like 5814
ARM repeat Protein kinase-like (PK-like) 5723
FnI-like domain FnI-like domain 5638
vWA-like Trypsin-like serine proteases 567
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 5515
Cysteine-rich domain Cysteine-rich domain 5421
Hormone receptor domain Family A G protein-coupled receptor-like 546
Spermadhesin, CUB domain Complement control module/SCR domain 5324
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 5316
SAM/Pointed domain SAM/Pointed domain 5214
Immunoglobulin Concanavalin A-like lectins/glucanases 5210
EF-hand PH domain-like 5112
WW domain PH domain-like 5115
GTPase activation domain, GAP SH3-domain 5121
Protein kinase-like (PK-like) Cysteine-rich domain 5117
EF-hand RING/U-box 5012
P-loop containing nucleoside triphosphate hydrolases Translation proteins 5015
ENTH/VHS domain GAT-like domain 503
Spectrin repeat EF-hand 4927
EF-hand PLC-like phosphodiesterases 4915
POZ domain Voltage-gated potassium channels 483
EGF/Laminin Complement control module/SCR domain 4728
C-type lectin-like C-type lectin-like 4619
cAMP-binding domain-like cAMP-binding domain-like 4611
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 467
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 4613
ArfGap/RecO-like zinc finger Ankyrin repeat 4612
C2 domain (Calcium/lipid-binding domain, CaLB) GTPase activation domain, GAP 4613
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 468
Actin depolymerizing proteins Actin depolymerizing proteins 4518
F-box domain RNI-like 455
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 446
DEATH domain Caspase-like 445
Growth factor receptor domain Concanavalin A-like lectins/glucanases 4428
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 4419
RING/U-box Cysteine proteinases 4411
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 436
(Trans)glycosidases Glycosyl hydrolase domain 4312
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 4313
Protein kinase-like (PK-like) SAM/Pointed domain 4313
Growth factor receptor domain Protein kinase-like (PK-like) 4313
L27 domain SH3-domain 438
P-loop containing nucleoside triphosphate hydrolases PH domain-like 4310
Spermadhesin, CUB domain EGF/Laminin 4320
vWA-like Integrin domains 4220
Voltage-gated potassium channels E set domains 423
A DNA-binding domain in eukaryotic transcription factors Leucine zipper domain 425
DEATH domain DEATH domain 417
SRCR-like Trypsin-like serine proteases 4110
ABC transporter transmembrane region ABC transporter transmembrane region 417
Immunoglobulin (Phosphotyrosine protein) phosphatases II 418
PH domain-like PLC-like phosphodiesterases 408
Kringle-like Kringle-like 4022
Thioredoxin-like Thioredoxin-like 4013
Integrin domains Integrin domains 4010
Voltage-gated potassium channels cAMP-binding domain-like 406
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 4014
Protein kinase-like (PK-like) Ubiquitin-like 409
P-loop containing nucleoside triphosphate hydrolases Transducin (alpha subunit), insertion domain 403
Spectrin repeat PH domain-like 3922
P-loop containing nucleoside triphosphate hydrolases Myosin rod fragments 3914
L27 domain P-loop containing nucleoside triphosphate hydrolases 395
Nucleotide-diphospho-sugar transferases Ricin B-like lectins 393
Integrin alpha N-terminal domain Integrin domains 399
Bromodomain Tudor/PWWP/MBT 397
vWA-like EGF/Laminin 3821
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 3813
Snake toxin-like Protein kinase-like (PK-like) 385
Myosin rod fragments Myosin rod fragments 3814
Ubiquitin-like Ras GEF 3813
SRCR-like SRCR-like 3816
PH domain-like ARM repeat 3816
ARM repeat Formin homology 2 domain (FH2 domain) 374
Galactose-binding domain-like Growth factor receptor domain 3718
SAM/Pointed domain "Winged helix" DNA-binding domain 377
RNI-like RNI-like 378
Ubiquitin-like PDZ domain-like 3715
Ankyrin repeat P-loop containing nucleoside triphosphate hydrolases 3718
beta-beta-alpha zinc fingers Homeodomain-like 3712
Cysteine-rich domain GTPase activation domain, GAP 378
GroEL equatorial domain-like GroEL apical domain-like 378
L domain-like Protein kinase-like (PK-like) 377
Metalloproteases ("zincins"), catalytic domain Hemopexin-like domain 378
Ankyrin repeat SET domain 373
Cysteine proteinases Calpain large subunit, middle domain (domain III) 378
C2 domain (Calcium/lipid-binding domain, CaLB) Protein kinase-like (PK-like) 3711
Chromo domain-like Chromo domain-like 3711
Galactose-binding domain-like Fibronectin type III 3613
PH domain-like Ankyrin repeat 3614
Ankyrin repeat SOCS box-like 366
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 363
Growth factor receptor domain Fibronectin type III 3617
RING/U-box TRAF domain-like 3615
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 3618
Calponin-homology domain, CH-domain EF-hand 3615
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 367
PH domain-like Oxysterol-binding protein-like 365
LDL receptor-like module Trypsin-like serine proteases 3612
BAR/IMD domain-like GTPase activation domain, GAP 3511
Nucleic acid-binding proteins Nucleic acid-binding proteins 3516
SH2 domain SH2 domain 3511
(Phosphotyrosine protein) phosphatases II C2 domain (Calcium/lipid-binding domain, CaLB) 3510
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 346
Kazal-type serine protease inhibitors EF-hand 3410
WW domain Hect, E3 ligase catalytic domain 3416
GroEL-intermediate domain like GroEL apical domain-like 347
Clavaminate synthase-like FYVE/PHD zinc finger 3410
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 349
PGBD-like Metalloproteases ("zincins"), catalytic domain 347
Protein kinase-like (PK-like) KA1-like 344
L domain-like Growth factor receptor domain 3313
Galactose-binding domain-like Concanavalin A-like lectins/glucanases 339
EGF/Laminin Trypsin-like serine proteases 3313
"Winged helix" DNA-binding domain SMAD/FHA domain 335
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 335
Glucocorticoid receptor-like (DNA-binding domain) Homeodomain-like 335
Growth factor receptor domain TB module/8-cys domain 3327
Cysteine-rich domain C2 domain (Calcium/lipid-binding domain, CaLB) 3310
Fibronectin type III SAM/Pointed domain 3310
BRCT domain BRCT domain 3214
TB module/8-cys domain EGF/Laminin 3227
GroEL equatorial domain-like GroEL-intermediate domain like 325
Protein kinase-like (PK-like) NTF2-like 322
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 324
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 318
Terpenoid cyclases/Protein prenyltransferases Alpha-macroglobulin receptor domain 316
RING/U-box FYVE/PHD zinc finger 319
CCCH zinc finger CCCH zinc finger 3117
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 319
Plexin repeat vWA-like 3012
Galactose-binding domain-like SAM/Pointed domain 308
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 308
HMG-box HMG-box 307
B-box zinc-binding domain Fibronectin type III 305
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 308
p53-like transcription factors p53 tetramerization domain 306
Clc chloride channel CBS-domain pair 305
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 3012
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 307
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 3014
LDL receptor-like module YWTD domain 2921
Galactose-binding domain-like Galactose-binding domain-like 2910
PH domain-like WD40 repeat-like 2913
Metalloproteases ("zincins"), catalytic domain TSP-1 type 1 repeat 2911
Calponin-homology domain, CH-domain PH domain-like 2913
C2 domain (Calcium/lipid-binding domain, CaLB) WW domain 2913
C2 domain (Calcium/lipid-binding domain, CaLB) vWA-like 293
Immunoglobulin Toll/Interleukin receptor TIR domain 2910
CRAL/TRIO N-terminal domain CRAL/TRIO domain 297
Ankyrin repeat DEATH domain 2911
Transducin (heterotrimeric G protein), gamma chain Regulator of G-protein signaling, RGS 293
Protease propeptides/inhibitors Subtilisin-like 2913
HIT/MYND zinc finger-like Tudor/PWWP/MBT 285
Ubiquitin-like Formin homology 2 domain (FH2 domain) 281
Sema domain Immunoglobulin 283
ClpP/crotonase ClpP/crotonase 287
TB module/8-cys domain TB module/8-cys domain 2823
Plexin repeat Immunoglobulin 283
LDL receptor-like module SRCR-like 289
Ras GEF Cysteine-rich domain 284
FnI-like domain Growth factor receptor domain 2814
Sec7 domain PH domain-like 284
Kelch motif Kelch motif 289
PH domain-like SAM/Pointed domain 2815
Spermadhesin, CUB domain Trypsin-like serine proteases 2813
Ubiquitin-like UBA-like 2811
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 287
MFS general substrate transporter Kazal-type serine protease inhibitors 283
PDZ domain-like Glucocorticoid receptor-like (DNA-binding domain) 2812
YWTD domain EGF/Laminin 2722
"Winged helix" DNA-binding domain Transducin (heterotrimeric G protein), gamma chain 272
p53-like transcription factors SH2 domain 276
PGBD-like Hemopexin-like domain 275
FKBP-like TPR-like 273
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 278
"Winged helix" DNA-binding domain Regulator of G-protein signaling, RGS 272
EF-hand Cysteine-rich domain 278
SET domain beta-beta-alpha zinc fingers 2712
vWA-like Fibronectin type III 2615
Periplasmic binding protein-like II Voltage-gated potassium channels 263
Cap-Gly domain Cap-Gly domain 269
Cullin homology domain "Winged helix" DNA-binding domain 264
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 2610
Immunoglobulin C-type lectin-like 2610
ARM repeat Clathrin adaptor appendage domain 266
Immunoglobulin TSP-1 type 1 repeat 2613
Galactose-binding domain-like EGF/Laminin 268
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 267
Periplasmic binding protein-like I Voltage-gated potassium channels 263
FYVE/PHD zinc finger SET domain 269
"Winged helix" DNA-binding domain E2F-DP heterodimerization region 264
Ankyrin repeat SAM/Pointed domain 2612
STAT p53-like transcription factors 255
PX domain Protein kinase-like (PK-like) 255
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 255
Cysteine-rich domain NAD kinase/diacylglycerol kinase-like 2512
Spectrin repeat DBL homology domain (DH-domain) 2514
vWA-like Integrin beta tail domain 2510
Tudor/PWWP/MBT SAM/Pointed domain 256
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 259
RING/U-box Fibronectin type III 254
Growth factor receptor domain TSP-1 type 1 repeat 258
L domain-like Fibronectin type III 258
Transcription factor STAT-4 N-domain STAT 254
Fibronectin type III Fibrinogen C-terminal domain-like 2515
Bromodomain HIT/MYND zinc finger-like 254
Spermadhesin, CUB domain LDL receptor-like module 2513
Ankyrin repeat Protein kinase-like (PK-like) 249
GAF domain-like HD-domain/PDEase-like 247
FYVE/PHD zinc finger C2 domain (Calcium/lipid-binding domain, CaLB) 246
EGF/Laminin LDL receptor-like module 2419
STAT SH2 domain 244
Thiolase-like Thiolase-like 244
Calpain large subunit, middle domain (domain III) EF-hand 245
Growth factor receptor domain YWTD domain 2419
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 248
PDZ domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 249
PX domain SH3-domain 248
Complement control module/SCR domain Periplasmic binding protein-like I 243
PKD domain PKD domain 248
Class II aaRS and biotin synthetases Class II aaRS ABD-related 247
C-type lectin-like Complement control module/SCR domain 2415
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 245
BAR/IMD domain-like PH domain-like 249
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 245
CoA-dependent acyltransferases CoA-dependent acyltransferases 243
PreATP-grasp domain Rudiment single hybrid motif 247
CalX-like CalX-like 248
Rhodanese/Cell cycle control phosphatase (Phosphotyrosine protein) phosphatases II 233
L domain-like Family A G protein-coupled receptor-like 2310
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 2311
Spectrin repeat Plakin repeat 2313
F-box domain WD40 repeat-like 235
DPP6 N-terminal domain-like alpha/beta-Hydrolases 233
Cysteine proteinases EF-hand 235
SMAD MH1 domain SMAD/FHA domain 233
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 235
EGF/Laminin Integrin beta tail domain 238
Cullin repeat-like "Winged helix" DNA-binding domain 232
Calponin-homology domain, CH-domain GAS2 domain-like 239
WD40 repeat-like ARM repeat 2318
Cullin repeat-like Cullin homology domain 232
Subtilisin-like Galactose-binding domain-like 2312
Concanavalin A-like lectins/glucanases (Phosphotyrosine protein) phosphatases II 231
Chaperone J-domain HSP40/DnaJ peptide-binding domain 227
Plakin repeat Plakin repeat 2211
P-loop containing nucleoside triphosphate hydrolases EF-hand 224
Serine protease inhibitors Serine protease inhibitors 2213
Nucleotide cyclase Nucleotide cyclase 224
Doublecortin (DC) Doublecortin (DC) 227
Transcription factor STAT-4 N-domain p53-like transcription factors 223
CRAL/TRIO domain DBL homology domain (DH-domain) 2211
PA domain Zn-dependent exopeptidases 224
EF-hand SH3-domain 2211
Integrin domains EGF/Laminin 2210
Plexin repeat Integrin beta tail domain 227
C-type lectin-like EGF/Laminin 2218
Immunoglobulin EGF/Laminin 228
alpha-catenin/vinculin-like alpha-catenin/vinculin-like 2213
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 227
cAMP-binding domain-like Ras GEF 2210
Ubiquitin-like C2 domain (Calcium/lipid-binding domain, CaLB) 226
POZ domain POZ domain 2110
Protease propeptides/inhibitors Zn-dependent exopeptidases 211
Kringle-like Trypsin-like serine proteases 2113
EF-hand Thyroglobulin type-1 domain 215
"Winged helix" DNA-binding domain Ubiquitin-like 217
Inhibitor of apoptosis (IAP) repeat Inhibitor of apoptosis (IAP) repeat 217
CRAL/TRIO domain PH domain-like 2110
Integrin domains Integrin beta tail domain 219
Galactose-binding domain-like Fibrinogen C-terminal domain-like 215
Glucocorticoid receptor-like (DNA-binding domain) VHP, Villin headpiece domain 213
Plexin repeat EGF/Laminin 216
Glucocorticoid receptor-like (DNA-binding domain) AN1-like Zinc finger 212
Alpha-macroglobulin receptor domain TIMP-like 212
Anaphylotoxins (complement system) Alpha-macroglobulin receptor domain 212
Anaphylotoxins (complement system) Terpenoid cyclases/Protein prenyltransferases 212
C2 domain (Calcium/lipid-binding domain, CaLB) Hect, E3 ligase catalytic domain 219
P-loop containing nucleoside triphosphate hydrolases BRK domain-like 213
Terpenoid cyclases/Protein prenyltransferases TIMP-like 212
Nucleic acid-binding proteins Translation proteins SH3-like domain 212
TAFH domain-like HIT/MYND zinc finger-like 211
CRAL/TRIO domain Supernatant protein factor (SPF), C-terminal domain 214
Growth factor receptor domain SAM/Pointed domain 217
C2 domain (Calcium/lipid-binding domain, CaLB) ARM repeat 216
Concanavalin A-like lectins/glucanases Fibrinogen C-terminal domain-like 215
Transcription factor STAT-4 N-domain SH2 domain 212
PA domain RING/U-box 213
L domain-like Toll/Interleukin receptor TIR domain 2112
Anaphylotoxins (complement system) TIMP-like 212
Protease propeptides/inhibitors Galactose-binding domain-like 2110
Ankyrin repeat SH3-domain 2110
EGF/Laminin Fibronectin type III 2115
Bactericidal permeability-increasing protein, BPI Bactericidal permeability-increasing protein, BPI 203
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 207
Cysteine-rich domain Ubiquitin-like 208
WW domain PDZ domain-like 2012
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 206
DBL homology domain (DH-domain) C2 domain (Calcium/lipid-binding domain, CaLB) 206
Ras GEF EF-hand 205
EGF/Laminin Fibrinogen C-terminal domain-like 205
Enolase N-terminal domain-like Enolase C-terminal domain-like 202
WD40 repeat-like RING/U-box 2011
beta-sandwich domain of Sec23/24 vWA-like 209
Kazal-type serine protease inhibitors Thyroglobulin type-1 domain 204
vWA-like Concanavalin A-like lectins/glucanases 209
DNA/RNA polymerases Ribonuclease H-like 207
BPTI-like BPTI-like 2012
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 209
PDZ domain-like SAM/Pointed domain 208
BEACH domain WD40 repeat-like 2014
SH2 domain SOCS box-like 202
Spermadhesin, CUB domain Galactose-binding domain-like 206
GAF domain-like GAF domain-like 205
Rudiment single hybrid motif Single hybrid motif 205
PAZ domain Ribonuclease H-like 204
Plexin repeat Integrin domains 208
Sema domain E set domains 208
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit cAMP-binding domain-like 202
CRAL/TRIO domain Spectrin repeat 2011
Plexin repeat E set domains 208
PDZ domain-like Protein kinase-like (PK-like) 209
Cysteine proteinases DUSP-like 2011
Intermediate filament protein, coiled coil region Prefoldin 207
Glutathione synthetase ATP-binding domain-like Single hybrid motif 205
GroES-like GroES-like 191
C2 domain (Calcium/lipid-binding domain, CaLB) SH2 domain 195
E set domains Cysteine proteinases 194
NTF2-like RNA-binding domain, RBD 197
PH domain-like FYVE/PHD zinc finger 197
FYVE/PHD zinc finger HIT/MYND zinc finger-like 193
Ubiquitin-like ARM repeat 195
Second domain of FERM Moesin tail domain 194
PH domain-like Regulator of G-protein signaling, RGS 198
(Trans)glycosidases Chitinase insertion domain 193
P-loop containing nucleoside triphosphate hydrolases Phosphoglycerate mutase-like 191
Phospholipase D/nuclease Phospholipase D/nuclease 195
PH domain-like BEACH domain 1913
Zn-dependent exopeptidases Transferrin receptor-like dimerisation domain 193
"Winged helix" DNA-binding domain RNA-binding domain, RBD 195
Protein kinase-like (PK-like) DEATH domain 197
Dimerization cofactor of HNF-1 alpha lambda repressor-like DNA-binding domains 195
Cysteine proteinases Transglutaminase, two C-terminal domains 194
A heparin-binding domain Amyloid beta a4 protein copper binding domain (domain 2) 198
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 192
FnI-like domain EGF/Laminin 1811
Cadherin-like Concanavalin A-like lectins/glucanases 1813
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 186
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 182
FnI-like domain Kringle-like 1810
SH2 domain Ubiquitin-like 184
E set domains Transglutaminase, two C-terminal domains 183
PH domain-like Moesin tail domain 183
FYVE/PHD zinc finger P-loop containing nucleoside triphosphate hydrolases 188
Flavoproteins Riboflavin synthase domain-like 1811
A heparin-binding domain CAPPD, an extracellular domain of amyloid beta A4 protein 187
PYP-like sensor domain (PAS domain) Voltage-gated potassium channels 185
P-loop containing nucleoside triphosphate hydrolases Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 182
Transglutaminase, two C-terminal domains Transglutaminase, two C-terminal domains 184
Second domain of FERM PDZ domain-like 188
SEA domain Trypsin-like serine proteases 186
PA domain Transferrin receptor-like dimerisation domain 182
Kazal-type serine protease inhibitors Kazal-type serine protease inhibitors 1713
WW domain GTPase activation domain, GAP 179
HLH, helix-loop-helix DNA-binding domain Orange domain-like 172
EF-hand C-terminal domain of PLC-beta 173
"Winged helix" DNA-binding domain FYVE/PHD zinc finger 178
Second domain of FERM Protein kinase-like (PK-like) 176
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 171
PUA domain-like RING/U-box 177
RNA-binding domain, RBD Ran binding protein zinc finger-like 173
Growth factor receptor domain Thyroglobulin type-1 domain 176
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 177
TPR-like Clavaminate synthase-like 178
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 173
PreATP-grasp domain Single hybrid motif 174
Serum albumin-like Serum albumin-like 173
PLC-like phosphodiesterases C-terminal domain of PLC-beta 173
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 1710
C2 domain (Calcium/lipid-binding domain, CaLB) C-terminal domain of PLC-beta 173
vWA-like Helical domain of Sec23/24 177
Amyloid beta a4 protein copper binding domain (domain 2) CAPPD, an extracellular domain of amyloid beta A4 protein 176
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 177
AN1-like Zinc finger AN1-like Zinc finger 172
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 173
Regulator of G-protein signaling, RGS Protein kinase-like (PK-like) 173
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 177
vWA-like Integrin alpha N-terminal domain 177
SH2 domain GTPase activation domain, GAP 168
Ligand-binding domain in the NO signalling and Golgi transport Nucleotide cyclase 162
Calponin-homology domain, CH-domain Glucocorticoid receptor-like (DNA-binding domain) 165
SH3-domain Fibronectin type III 169
WW domain EF-hand 166
Ran binding protein zinc finger-like RING/U-box 169
Starch-binding domain-like Starch-binding domain-like 162
Zn-dependent exopeptidases Carboxypeptidase regulatory domain-like 169
P-loop containing nucleoside triphosphate hydrolases Bromodomain 163
(Phosphotyrosine protein) phosphatases II SH2 domain 164
PDZ domain-like DBL homology domain (DH-domain) 167
Spectrin repeat WW domain 166
MIR domain IP3 receptor type 1 binding core, domain 2 167
L domain-like PDZ domain-like 167
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 164
Starch-binding domain-like Carboxypeptidase regulatory domain-like 162
Cysteine-rich domain DBL homology domain (DH-domain) 164
PYP-like sensor domain (PAS domain) cAMP-binding domain-like 163
ARM repeat Subdomain of clathrin and coatomer appendage domain 162
MIR domain MIR domain 167
Cystine-knot cytokines Heparin-binding domain from vascular endothelial growth factor 162
Snake toxin-like Snake toxin-like 167
RNA-binding domain, RBD dsRNA-binding domain-like 164
alpha-ketoacid dehydrogenase kinase, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 162
WW domain RING/U-box 166
Concanavalin A-like lectins/glucanases P-loop containing nucleoside triphosphate hydrolases 165
vWA-like C-terminal, gelsolin-like domain of Sec23/24 166
F-box domain Galactose-binding domain-like 163
SH3-domain SAM/Pointed domain 167
lambda repressor-like DNA-binding domains lambda repressor-like DNA-binding domains 164
PH domain-like C-terminal domain of PLC-beta 162
MFS general substrate transporter MFS general substrate transporter 167
LDL receptor-like module Growth factor receptor domain 1612
Spectrin repeat RING/U-box 166
TPR-like RING/U-box 166
Lipase/lipooxygenase domain (PLAT/LH2 domain) Lipoxigenase 162
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 163
Second domain of FERM Second domain of FERM 164
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 166
YWTD domain YWTD domain 1614
CCCH zinc finger RING/U-box 168
Myosin S1 fragment, N-terminal domain P-loop containing nucleoside triphosphate hydrolases 152
Glycoside hydrolase/deacetylase Galactose mutarotase-like 155
Ubiquitin-like GTPase activation domain, GAP 156
Ribonuclease H-like RNA-binding domain, RBD 155
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 151
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 153
HIN-2000 domain-like HIN-2000 domain-like 155
ARID-like Clavaminate synthase-like 154
P-loop containing nucleoside triphosphate hydrolases GTPase activation domain, GAP 154
HSP40/DnaJ peptide-binding domain DnaJ/Hsp40 cysteine-rich domain 156
Sema domain GTPase activation domain, GAP 157
TNF receptor-like DEATH domain 156
RING/U-box P-loop containing nucleoside triphosphate hydrolases 157
IP3 receptor type 1 binding core, domain 2 IP3 receptor type 1 binding core, domain 2 156
CRAL/TRIO N-terminal domain Supernatant protein factor (SPF), C-terminal domain 152
TRAF domain-like TRAF domain-like 159
PsbU/PolX domain-like Nucleotidyltransferase 155
Ribosomal L27 protein-like Nucleic acid-binding proteins 152
B-box zinc-binding domain FYVE/PHD zinc finger 157
Calponin-homology domain, CH-domain DBL homology domain (DH-domain) 155
KRAB domain (Kruppel-associated box) KRAB domain (Kruppel-associated box) 1510
FYVE/PHD zinc finger SMAD/FHA domain 152
EF-hand GAS2 domain-like 1513
Folate-binding domain Aminomethyltransferase beta-barrel domain 153
Guanido kinase N-terminal domain Glutamine synthetase/guanido kinase 152
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 155
Cupredoxins Cupredoxins 159
PH domain-like Ras GEF 156
Zn-finger domain of Sec23/24 vWA-like 155
Concanavalin A-like lectins/glucanases FnI-like domain 158
Ubiquitin-like Moesin tail domain 152
Zn-finger domain of Sec23/24 beta-sandwich domain of Sec23/24 155
RCC1/BLIP-II Hect, E3 ligase catalytic domain 144
t-snare proteins SNARE fusion complex 142
Myosin S1 fragment, N-terminal domain Myosin rod fragments 141
Calponin-homology domain, CH-domain SH3-domain 144
Calponin-homology domain, CH-domain E set domains 144
SH3-domain WW domain 147
Chromo domain-like ClpP/crotonase 142
P-loop containing nucleoside triphosphate hydrolases WW domain 149
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 146
Ubiquitin-like Cysteine proteinases 146
RNA-binding domain, RBD L domain-like 145
beta-beta-alpha zinc fingers Leucine zipper domain 142
RING/U-box Ankyrin repeat 147
Ubiquitin-like DBL homology domain (DH-domain) 143
GLA-domain EGF/Laminin 145
Galactose mutarotase-like (Trans)glycosidases 147
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 142
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 1410
Translation proteins EF-G C-terminal domain-like 145
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 145
Dimerization cofactor of HNF-1 alpha Homeodomain-like 144
ARID-like FYVE/PHD zinc finger 144
vWA-like Chicken cartilage matrix protein 1411
GST C-terminal domain-like Nucleotidylyl transferase 149
L domain-like NTF2-like 144
Plexin repeat GTPase activation domain, GAP 146
Spermadhesin, CUB domain Concanavalin A-like lectins/glucanases 144
SWIB/MDM2 domain Ran binding protein zinc finger-like 147
CCHHC domain CCHHC domain 147
Ubiquitin-like RING/U-box 147
Myosin rod fragments Tropomyosin 145
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 145
RING/U-box UBA-like 148
Spectrin repeat SH3-domain 1411
Galactose-binding domain-like (Trans)glycosidases 146
alpha/beta-Hydrolases Lipase/lipooxygenase domain (PLAT/LH2 domain) 141
Protein kinase-like (PK-like) FAT domain of focal adhesion kinase 145
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 147
WWE domain ADP-ribosylation 133
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Elongation factor TFIIS domain 2 134
DBL homology domain (DH-domain) GTPase activation domain, GAP 133
RING/U-box BRCT domain 136
Cystatin/monellin Cystatin/monellin 134
HR1 repeat SH3-domain 132
CBS-domain pair CBS-domain pair 132
NAD kinase/diacylglycerol kinase-like Ankyrin repeat 131
E set domains Ankyrin repeat 134
EF-G C-terminal domain-like EF-G C-terminal domain-like 134
EF-hand Mitochondrial carrier 132
BAR/IMD domain-like HR1 repeat 132
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 132
RING/U-box Mib/herc2 domain-like 137
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 136
Somatomedin B domain Somatomedin B domain 137
Ankyrin repeat Mib/herc2 domain-like 135
Ubiquitin-like P-loop containing nucleoside triphosphate hydrolases 133
DNA polymerase beta, N-terminal domain-like PsbU/PolX domain-like 134
vWA-like Growth factor receptor domain 1312
Translation proteins Ribosomal protein S5 domain 2-like 134
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 133
L domain-like EGF/Laminin 138
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 135
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 134
Second domain of FERM (Phosphotyrosine protein) phosphatases II 135
WWE domain RING/U-box 133
Spectrin repeat GAS2 domain-like 1311
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 134
p53-like transcription factors DNA-binding protein LAG-1 (CSL) 133
"Winged helix" DNA-binding domain Ras GEF 135
CAD & PB1 domains Protein kinase-like (PK-like) 134
SAND domain-like FYVE/PHD zinc finger 134
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 134
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 133
Heme-dependent peroxidases EGF/Laminin 136
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 133
Calponin-homology domain, CH-domain Plakin repeat 135
PR-1-like C-type lectin-like 131
E set domains GTPase activation domain, GAP 135
GLA-domain Trypsin-like serine proteases 133
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 132
Voltage-gated potassium channels Small-conductance potassium channel 133
Concanavalin A-like lectins/glucanases ARM repeat 139
PH domain-like Ypt/Rab-GAP domain of gyp1p 136
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 133
Ankyrin repeat POZ domain 1311
SH3-domain C2 domain (Calcium/lipid-binding domain, CaLB) 135
RNA-binding domain, RBD PABC (PABP) domain 123
Inhibitor of apoptosis (IAP) repeat P-loop containing nucleoside triphosphate hydrolases 122
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 123
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 123
Eukaryotic type KH-domain (KH-domain type I) Tudor/PWWP/MBT 123
BAR/IMD domain-like Ankyrin repeat 125
GTF2I-like repeat GTF2I-like repeat 125
N-terminal domain of adenylylcyclase associated protein, CAP C-terminal domain of adenylylcyclase associated protein 122
TSP type-3 repeat TSP type-3 repeat 128
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 127
Inhibitor of apoptosis (IAP) repeat RNI-like 122
Calponin-homology domain, CH-domain P-loop containing nucleoside triphosphate hydrolases 125
FnI-like domain TSP-1 type 1 repeat 123
ARM repeat Rap/Ran-GAP 123
RING/U-box SAM/Pointed domain 124
Protein kinase-like (PK-like) MIT domain 123
PK beta-barrel domain-like PK C-terminal domain-like 122
FAD/NAD(P)-binding domain Glucocorticoid receptor-like (DNA-binding domain) 123
BRCT domain DNA polymerase beta, N-terminal domain-like 126
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 124
BRK domain-like Bromodomain 121
SWIB/MDM2 domain RING/U-box 126
Immunoglobulin DEATH domain 124
PH domain-like FAT domain of focal adhesion kinase 123
Metalloproteases ("zincins"), catalytic domain Spermadhesin, CUB domain 127
Subtilisin-like Growth factor receptor domain 127
FAS1 domain FAS1 domain 125
PDZ domain-like Regulator of G-protein signaling, RGS 125
EF-hand NAD kinase/diacylglycerol kinase-like 125
SAP domain RING/U-box 125
TPR-like ARM repeat 125
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 124
"Winged helix" DNA-binding domain cAMP-binding domain-like 124
UBA-like Cysteine proteinases 124
(Trans)glycosidases (Trans)glycosidases 129
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 125
FKBP-like FKBP-like 126
SAP domain RNA-binding domain, RBD 123
FAD/NAD(P)-binding domain Calponin-homology domain, CH-domain 123
P-loop containing nucleoside triphosphate hydrolases ARM repeat 128
Galactose mutarotase-like Glycosyl hydrolase domain 126
Putative DNA-binding domain SAND domain-like 122
cAMP-binding domain-like Ubiquitin-like 124
BAR/IMD domain-like ArfGap/RecO-like zinc finger 125
Concanavalin A-like lectins/glucanases TSP type-3 repeat 128
TGS-like ThrRS/AlaRS common domain 123
DBL homology domain (DH-domain) WD40 repeat-like 122
EGF/Laminin TSP type-3 repeat 128
TPR-like PH domain-like 122
P-loop containing nucleoside triphosphate hydrolases ArfGap/RecO-like zinc finger 124
Protein kinase-like (PK-like) Polo-box domain 124
Cadherin-like EGF/Laminin 1110
CRAL/TRIO domain GTPase activation domain, GAP 113
RUN domain-like FYVE/PHD zinc finger 113
FnI-like domain Fibronectin type III 116
Surp module (SWAP domain) Surp module (SWAP domain) 114
ARM repeat BEACH domain 118
Concanavalin A-like lectins/glucanases WD40 repeat-like 118
Ubiquitin-like SMAD/FHA domain 115
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 115
Glycosyl hydrolase domain Glycosyl hydrolase domain 115
FYVE/PHD zinc finger HMG-box 115
Transcription factor IIA (TFIIA), alpha-helical domain Transcription factor IIA (TFIIA), beta-barrel domain 113
TATA-box binding protein-like DNA-glycosylase 112
Metalloproteases ("zincins"), catalytic domain ARM repeat 114
Immunoglobulin Complement control module/SCR domain 115
Tudor/PWWP/MBT S-adenosyl-L-methionine-dependent methyltransferases 112
P-loop containing nucleoside triphosphate hydrolases Second domain of FERM 114
Restriction endonuclease-like RuvA domain 2-like 113
PRTase-like PRTase-like 111
Ran binding protein zinc finger-like Ran binding protein zinc finger-like 116
L domain-like Calponin-homology domain, CH-domain 112
Regulator of G-protein signaling, RGS Ubiquitin-like 114
UBA-like UBA-like 118
DNA-binding protein LAG-1 (CSL) E set domains 112
ArfGap/RecO-like zinc finger GTPase activation domain, GAP 117
Tudor/PWWP/MBT SET domain 113
MAST3 pre-PK domain-like Protein kinase-like (PK-like) 113
RNase III domain-like RNase III domain-like 115
Ubiquitin-like FAT domain of focal adhesion kinase 112
Second domain of FERM FAT domain of focal adhesion kinase 112
SEA domain Spermadhesin, CUB domain 116
Rap/Ran-GAP PDZ domain-like 114
Trypsin-like serine proteases Trypsin-like serine proteases 118
RNA-binding domain, RBD Retrovirus zinc finger-like domains 112
PAH2 domain PAH2 domain 114
Ubiquitin-like (Phosphotyrosine protein) phosphatases II 114
Mib/herc2 domain-like Mib/herc2 domain-like 115
DNA-glycosylase Nudix 112
FYVE/PHD zinc finger RNI-like 114
BAR/IMD domain-like Cysteine-rich domain 113
Protease propeptides/inhibitors Growth factor receptor domain 116
Kazal-type serine protease inhibitors EGF/Laminin 114
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 114
SAND domain-like Bromodomain 112
Amine oxidase N-terminal region Amine oxidase N-terminal region 113
RNase III domain-like dsRNA-binding domain-like 104
Tudor/PWWP/MBT HMG-box 102
SMAD/FHA domain PH domain-like 102
SNARE fusion complex SNARE fusion complex 103
Second domain of FERM SH3-domain 104
"Winged helix" DNA-binding domain PDZ domain-like 105
PDZ domain-like (Phosphotyrosine protein) phosphatases II 104
SEA domain LDL receptor-like module 105
P-loop containing nucleoside triphosphate hydrolases SOCS box-like 102
TSP-1 type 1 repeat DEATH domain 103
EF-hand Ferredoxin reductase-like, C-terminal NADP-linked domain 103
Single hybrid motif CoA-dependent acyltransferases 104
FAD-linked reductases, C-terminal domain Folate-binding domain 104
Notch domain Notch domain 107
vWA-like Cysteine-rich domain 102
SH3-domain S-adenosyl-L-methionine-dependent methyltransferases 101
FAD/NAD(P)-binding domain Folate-binding domain 104
Growth factor receptor domain Notch domain 107
EGF/Laminin Ankyrin repeat 107
B-box zinc-binding domain E set domains 106
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 104
SAM/Pointed domain GTPase activation domain, GAP 105
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 105
GTPase activation domain, GAP Bet v1-like 103
Regulator of G-protein signaling, RGS PX domain 103
Regulator of G-protein signaling, RGS DBL homology domain (DH-domain) 104
Nucleotidylyl transferase S15/NS1 RNA-binding domain 104
N-terminal coiled coil domain from apc Tumor suppressor gene product Apc 104
E set domains Terpenoid cyclases/Protein prenyltransferases 104
PX domain BAR/IMD domain-like 102
EF-hand Riboflavin synthase domain-like 103
Growth factor receptor domain Ankyrin repeat 107
PreATP-grasp domain ClpP/crotonase 102
ADC-like Cdc48 domain 2-like 103
L domain-like Concanavalin A-like lectins/glucanases 106
Hairpin loop containing domain-like Kringle-like 105
Concanavalin A-like lectins/glucanases BEACH domain 107
p53 tetramerization domain SAM/Pointed domain 103
LDL receptor-like module Frizzled cysteine-rich domain 106
Thyroglobulin type-1 domain Thyroglobulin type-1 domain 107
E set domains RING/U-box 105
PX domain Ubiquitin-like 103
Nucleotidyltransferase Nucleotidyltransferase 108
Notch domain Ankyrin repeat 107
Somatomedin B domain Alkaline phosphatase-like 105
EGF/Laminin Notch domain 107
ThrRS/AlaRS common domain Class II aaRS ABD-related 102
GAT-like domain Clathrin adaptor appendage domain 102
Leukotriene A4 hydrolase N-terminal domain ARM repeat 103
ARM repeat RING/U-box 106
ACT-like Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 102
Concanavalin A-like lectins/glucanases LDL receptor-like module 109
Amine oxidase N-terminal region Amine oxidase catalytic domain 102
Prefoldin WD40 repeat-like 103
DBL homology domain (DH-domain) SH2 domain 103
DBL homology domain (DH-domain) Ras GEF 104
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 104
Kringle-like Fibronectin type III 105
Heme-dependent peroxidases Complement control module/SCR domain 105
ARM repeat "Winged helix" DNA-binding domain 103
SH3-domain TPR-like 104
Nitric oxide (NO) synthase oxygenase domain Flavoproteins 106
RNA-binding domain, RBD UBA-like 102
Single hybrid motif ClpP/crotonase 102
Concanavalin A-like lectins/glucanases PH domain-like 107
Kazal-type serine protease inhibitors Immunoglobulin 105
Elafin-like Elafin-like 105
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 102
PYP-like sensor domain (PAS domain) Nuclear receptor coactivator interlocking domain 102
Inosine monophosphate dehydrogenase (IMPDH) Inosine monophosphate dehydrogenase (IMPDH) 102
Calponin-homology domain, CH-domain SH2 domain 103
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 105
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 102
Rudiment single hybrid motif ClpP/crotonase 102
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 102
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 102
p53-like transcription factors SAM/Pointed domain 103
FYVE/PHD zinc finger PDZ domain-like 104
E set domains Alpha-macroglobulin receptor domain 104
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 103
Bromodomain HMG-box 92
Hermes dimerisation domain Ribonuclease H-like 95
SRCR-like Spermadhesin, CUB domain 94
TGS-like Class II aaRS and biotin synthetases 91
Amyloid beta a4 protein copper binding domain (domain 2) BPTI-like 93
DEATH domain Inhibitor of apoptosis (IAP) repeat 94
Growth factor receptor domain Chicken cartilage matrix protein 98
Intermediate filament protein, coiled coil region Lamin A/C globular tail domain 96
RCC1/BLIP-II POZ domain 93
SMAD/FHA domain BRCT domain 92
Phosphofructokinase Phosphofructokinase 92
SH2 domain Ras GEF 93
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 93
HLH, helix-loop-helix DNA-binding domain Nuclear receptor coactivator interlocking domain 91
HR1 repeat HR1 repeat 97
Concanavalin A-like lectins/glucanases P-domain of calnexin/calreticulin 94
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 91
RING/U-box RNA-binding domain, RBD 92
Serine protease inhibitors FnI-like domain 98
Ankyrin repeat Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 98
Formyltransferase FMT C-terminal domain-like 93
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 97
Domain of poly(ADP-ribose) polymerase ADP-ribosylation 95
BPTI-like CAPPD, an extracellular domain of amyloid beta A4 protein 93
LCCL domain vWA-like 93
beta-beta-alpha zinc fingers Hermes dimerisation domain 95
ADC-like P-loop containing nucleoside triphosphate hydrolases 94
A heparin-binding domain BPTI-like 93
GST C-terminal domain-like Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 94
Kringle-like Spermadhesin, CUB domain 91
Macro domain-like ADP-ribosylation 94
S15/NS1 RNA-binding domain Class II aaRS and biotin synthetases 94
Ubiquitin-like SH3-domain 94
FYVE/PHD zinc finger SAP domain 92
Oligoxyloglucan reducing end-specific cellobiohydrolase PKD domain 93
ARM repeat Hect, E3 ligase catalytic domain 94
Chitinase insertion domain Invertebrate chitin-binding proteins 91
Triple coiled coil domain of C-type lectins C-type lectin-like 92
Regulator of G-protein signaling, RGS Regulator of G-protein signaling, RGS 95
Chaperone J-domain Thioredoxin-like 95
SMAD/FHA domain HIT-like 91
Thioredoxin-like Nucleoside diphosphate kinase, NDK 93
Actin depolymerizing proteins C-terminal, gelsolin-like domain of Sec23/24 97
EF-hand SH2 domain 93
Carboxypeptidase regulatory domain-like NHL repeat 95
Chromo domain-like BRK domain-like 92
Metalloproteases ("zincins"), catalytic domain EGF/Laminin 94
EF-hand Myosin rod fragments 92
cAMP-binding domain-like PDZ domain-like 95
Tudor/PWWP/MBT ARID-like 93
WD40 repeat-like Putative isomerase YbhE 93
TPR-like "Winged helix" DNA-binding domain 91
ENTH/VHS domain Clathrin adaptor appendage domain 91
PDZ domain-like Ras GEF 95
Midkine Midkine 92
DEATH domain B-box zinc-binding domain 92
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 91
Homeodomain-like RING/U-box 93
"Winged helix" DNA-binding domain Acyl-CoA N-acyltransferases (Nat) 92
RING/U-box Bromodomain 93
(Trans)glycosidases Invertebrate chitin-binding proteins 91
FYVE/PHD zinc finger Acyl-CoA N-acyltransferases (Nat) 92
B-box zinc-binding domain Bromodomain 94
RING/U-box NHL repeat 95
Ankyrin repeat TPR-like 97
FYVE/PHD zinc finger Chromo domain-like 94
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 93
Concanavalin A-like lectins/glucanases Family A G protein-coupled receptor-like 95
TGS-like Class II aaRS ABD-related 91
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 93
Lipase/lipooxygenase domain (PLAT/LH2 domain) Lipase/lipooxygenase domain (PLAT/LH2 domain) 97
PAP/OAS1 substrate-binding domain PAP/OAS1 substrate-binding domain 97
Nucleotidylyl transferase Nucleotidylyl transferase 91
SMAD/FHA domain Protein kinase-like (PK-like) 91
Actin depolymerizing proteins VHP, Villin headpiece domain 95
B-box zinc-binding domain NHL repeat 95
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 91
WW domain FF domain 95
RNI-like L domain-like 98
beta-beta-alpha zinc fingers Ribonuclease H-like 95
Elongation factor TFIIS domain 2 Zinc beta-ribbon 93
LDL receptor-like module L domain-like 85
DBL homology domain (DH-domain) FYVE/PHD zinc finger 83
Staphylococcal nuclease Tudor/PWWP/MBT 86
Pectin lyase-like Pectin lyase-like 85
PH domain-like NAD kinase/diacylglycerol kinase-like 83
Actin depolymerizing proteins SH3-domain 81
Growth factor receptor domain Family A G protein-coupled receptor-like 87
EGF/Laminin Family A G protein-coupled receptor-like 87
MIR domain ARM repeat 83
GTPase activation domain, GAP RGC domain-like 84
L27 domain L27 domain 83
SH2 domain Cysteine-rich domain 83
Ribosomal protein S5 domain 2-like HMG-box 82
SMAD/FHA domain PDZ domain-like 83
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 81
IP3 receptor type 1 binding core, domain 2 ARM repeat 83
PHM/PNGase F PHM/PNGase F 82
S15/NS1 RNA-binding domain Class II aaRS ABD-related 83
Fibrinogen coiled-coil and central regions Fibrinogen C-terminal domain-like 83
ENTH/VHS domain RNA-binding domain, RBD 83
FKBP-like EF-hand 85
MFS general substrate transporter Pentapeptide repeat-like 83
NAD(P)-binding Rossmann-fold domains SCP-like 83
BRCT domain Nucleotidyltransferase 83
P-loop containing nucleoside triphosphate hydrolases Prefoldin 81
MIR domain Concanavalin A-like lectins/glucanases 85
TATA-box binding protein-like TATA-box binding protein-like 82
EGF/Laminin Chicken cartilage matrix protein 86
beta-beta-alpha zinc fingers FYVE/PHD zinc finger 81
PAP/OAS1 substrate-binding domain Retrovirus zinc finger-like domains 86
PR-1-like Crisp domain-like 82
Tumor suppressor gene product Apc ARM repeat 83
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 86
Concanavalin A-like lectins/glucanases EF-hand 85
PH domain-like Tricorn protease domain 2 83
Calponin-homology domain, CH-domain PRC-barrel domain 81
BRCT domain PsbU/PolX domain-like 83
ARM repeat Ankyrin repeat 84
Cysteine-rich domain Tricorn protease domain 2 83
SAP domain P-loop containing nucleoside triphosphate hydrolases 83
TIMP-like EGF/Laminin 83
HMA, heavy metal-associated domain HAD-like 86
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 83
Formin homology 2 domain (FH2 domain) Protein kinase-like (PK-like) 82
Assembly domain of cartilage oligomeric matrix protein TSP type-3 repeat 86
SH3-domain RUN domain-like 83
vWA-like SPOC domain-like 82
SH3-domain CAD & PB1 domains 84
PLP-binding barrel Alanine racemase C-terminal domain-like 82
MIR domain EF-hand 85
WGR domain-like Domain of poly(ADP-ribose) polymerase 84
Nitric oxide (NO) synthase oxygenase domain Ferredoxin reductase-like, C-terminal NADP-linked domain 85
Macro domain-like Macro domain-like 84
Cysteine-rich domain (Phosphotyrosine protein) phosphatases II 82
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 83
MgtE membrane domain-like MgtE membrane domain-like 82
C2 domain (Calcium/lipid-binding domain, CaLB) FabD/lysophospholipase-like 84
Nitric oxide (NO) synthase oxygenase domain Riboflavin synthase domain-like 85
Growth factor receptor domain Complement control module/SCR domain 86
IP3 receptor type 1 binding core, domain 2 Concanavalin A-like lectins/glucanases 85
Tryptophan synthase beta subunit-like PLP-dependent enzymes CBS-domain pair 81
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 85
FF domain FF domain 84
DEK C-terminal domain (Phosphotyrosine protein) phosphatases II 83
Alkaline phosphatase-like Alkaline phosphatase-like 82
Nucleoside diphosphate kinase, NDK Nucleoside diphosphate kinase, NDK 83
Lipovitellin-phosvitin complex; beta-sheet shell regions Lipovitellin-phosvitin complex, superhelical domain 85
ARM repeat Galactose-binding domain-like 84
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 83
Saposin Saposin 84
PP2C-like Protein serine/threonine phosphatase 2C, C-terminal domain 83
Elafin-like BPTI-like 85
PurM N-terminal domain-like PurM C-terminal domain-like 84
Zinc beta-ribbon Cyclin-like 84
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 86
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 84
Assembly domain of cartilage oligomeric matrix protein EGF/Laminin 86
BRK domain-like BRK domain-like 83
Alkaline phosphatase-like His-Me finger endonucleases 83
TPR-like PUA domain-like 83
Ypt/Rab-GAP domain of gyp1p Rhodanese/Cell cycle control phosphatase 83
Phenylalanine zipper PH domain-like 84
Concanavalin A-like lectins/glucanases Assembly domain of cartilage oligomeric matrix protein 86
ARID-like Chromo domain-like 83
IP3 receptor type 1 binding core, domain 2 EF-hand 85
CAD & PB1 domains RING/U-box 85
DPP6 N-terminal domain-like WD40 repeat-like 86
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 73
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 72
WGR domain-like ADP-ribosylation 73
Ribosomal L27 protein-like Eukaryotic type KH-domain (KH-domain type I) 71
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 73
Ubiquitin-like PUA domain-like 73
RING/U-box DUSP-like 73
Concanavalin A-like lectins/glucanases Serine protease inhibitors 73
Ribosomal protein L6 Ribosomal protein L6 71
E set domains NHL repeat 74
Ypt/Rab-GAP domain of gyp1p RUN domain-like 72
Phenylalanine zipper SH2 domain 73
DBL homology domain (DH-domain) Protein kinase-like (PK-like) 75
p53-like transcription factors DEATH domain 72
(Phosphotyrosine protein) phosphatases II FYVE/PHD zinc finger 72
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 73
Translation proteins ThrRS/AlaRS common domain 74
GTPase activation domain, GAP VPS9 domain 71
Intermediate filament protein, coiled coil region Myosin rod fragments 75
TRAF domain-like POZ domain 72
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 71
Kazal-type serine protease inhibitors Trypsin-like serine proteases 73
FMT C-terminal domain-like ALDH-like 72
BAR/IMD domain-like Protein kinase-like (PK-like) 72
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 73
TSP-1 type 1 repeat Family A G protein-coupled receptor-like 72
P-loop containing nucleoside triphosphate hydrolases FF domain 72
Tudor/PWWP/MBT Chromo domain-like 72
Immunoglobulin SH3-domain 76
PH domain-like "Winged helix" DNA-binding domain 74
Ankyrin repeat Eukaryotic type KH-domain (KH-domain type I) 72
Casein kinase II beta subunit Snake toxin-like 71
POZ domain Skp1 dimerisation domain-like 71
beta-beta-alpha zinc fingers RNA-binding domain, RBD 75
Trypsin-like serine proteases PDZ domain-like 73
NAD(P)-binding Rossmann-fold domains Thioesterase/thiol ester dehydrase-isomerase 73
Cysteine proteinases HIT/MYND zinc finger-like 73
Ubiquitin-like FYVE/PHD zinc finger 73
Heat shock protein 70kD (HSP70), C-terminal subdomain Heat shock protein 70kD (HSP70), C-terminal subdomain 72
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 72
WD40 repeat-like Soluble quinoprotein glucose dehydrogenase 73
Polo-box domain Polo-box domain 73
Cap-Gly domain Ubiquitin-like 72
RNA-binding domain, RBD Eukaryotic type KH-domain (KH-domain type I) 74
vWA-like BPTI-like 75
Ricin B-like lectins C-type lectin-like 76
Ubiquitin-like Thioredoxin-like 76
SEA domain SEA domain 75
Clathrin heavy-chain terminal domain ARM repeat 72
HSP20-like chaperones Cysteine proteinases 73
Kelch motif Galactose oxidase, central domain 74
Plexin repeat TSP-1 type 1 repeat 73
RNA-binding domain, RBD SPOC domain-like 71
E set domains DEATH domain 72
RUN domain-like Lipase/lipooxygenase domain (PLAT/LH2 domain) 73
Histone-fold Macro domain-like 72
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 73
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 73
Growth factor receptor domain Mannose 6-phosphate receptor domain 73
Cap-Gly domain Cysteine proteinases 73
NTF2-like UBA-like 72
gamma-Crystallin-like gamma-Crystallin-like 73
Sema domain TSP-1 type 1 repeat 73
Protein kinase-like (PK-like) Nucleotide cyclase 74
Ankyrin repeat Cap-Gly domain 75
Concanavalin A-like lectins/glucanases Metalloproteases ("zincins"), catalytic domain 75
PDZ domain-like Myosin rod fragments 74
FAD-linked reductases, C-terminal domain Aminomethyltransferase beta-barrel domain 72
SH2 domain VPS9 domain 75
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 73
Ypt/Rab-GAP domain of gyp1p EF-hand 71
TRAF domain-like Trimerization domain of TRAF 75
USP8 N-terminal domain-like JAB1/MPN domain 72
HR1 repeat C2 domain (Calcium/lipid-binding domain, CaLB) 75
Fibronectin type III DBL homology domain (DH-domain) 75
HSP20-like chaperones HIT/MYND zinc finger-like 73
dsRNA-binding domain-like Cytokine 71
C-terminal domain of RNA polymerase alpha subunit P-loop containing nucleoside triphosphate hydrolases 71
WW domain BAR/IMD domain-like 73
DNA-binding domain SET domain 71
Glucocorticoid receptor-like (DNA-binding domain) Protein kinase-like (PK-like) 76
Chromo domain-like SET domain 71
p53-like transcription factors Ankyrin repeat 72
Fibronectin type III PH domain-like 75
Thioesterase/thiol ester dehydrase-isomerase SCP-like 73
HSP20-like chaperones HSP20-like chaperones 73
SAP domain Concanavalin A-like lectins/glucanases 72
TROVE domain-like vWA-like 71
Ankyrin repeat HIT/MYND zinc finger-like 76
cAMP-binding domain-like FabD/lysophospholipase-like 71
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 73
CRAL/TRIO domain SH3-domain 75
UBC-like RING/U-box 74
HMG-box SET domain 73
GFP-like Growth factor receptor domain 76
Growth factor receptor domain Spermadhesin, CUB domain 76
PEP carboxykinase N-terminal domain PEP carboxykinase-like 72
N-terminal coiled coil domain from apc ARM repeat 72
Growth factor receptor domain Kazal-type serine protease inhibitors 73
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 73
MAST3 pre-PK domain-like PDZ domain-like 71
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 CCCH zinc finger 71
(Trans)glycosidases Six-hairpin glycosidases 71
RNA-binding domain, RBD S-adenosyl-L-methionine-dependent methyltransferases 73
Ubiquitin-like Ran binding protein zinc finger-like 75
C2 domain (Calcium/lipid-binding domain, CaLB) PX domain 71
Trefoil Galactose mutarotase-like 75
FAD/NAD(P)-binding domain Aminomethyltransferase beta-barrel domain 72
WWE domain WWE domain 72
P-loop containing nucleoside triphosphate hydrolases Cysteine-rich domain 71
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 73
FYVE/PHD zinc finger PUA domain-like 73
Formyltransferase ALDH-like 72
ARM repeat PX domain 71
Somatomedin B domain His-Me finger endonucleases 72
Phoshotransferase/anion transport protein Phoshotransferase/anion transport protein 71
FYVE/PHD zinc finger Elongation factor TFIIS domain 2 72
HCP-like HCP-like 75
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 64
Nucleotide-binding domain Nucleotide-binding domain 63
Ribonuclease H-like R3H domain 62
Formyltransferase ACP-like 61
POZ domain Galactose-binding domain-like 62
DUSP-like DUSP-like 62
DNase I-like RNA-binding domain, RBD 62
Galactose-binding domain-like RING/U-box 64
Eukaryotic type KH-domain (KH-domain type I) LigT-like 62
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 61
NAD(P)-binding Rossmann-fold domains P-loop containing nucleoside triphosphate hydrolases 62
Thyroglobulin type-1 domain YWTD domain 65
PH domain-like Glycolipid transfer protein, GLTP 61
Sema domain Protein kinase-like (PK-like) 62
Carbonic anhydrase (Phosphotyrosine protein) phosphatases II 62
GFP-like Thyroglobulin type-1 domain 65
Metalloproteases ("zincins"), catalytic domain Kringle-like 63
ARM repeat Cysteine proteinases 64
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 64
L domain-like PP2C-like 64
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 64
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 62
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HMG-box 61
Fibronectin type III BPTI-like 64
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 62
TSP-1 type 1 repeat LDL receptor-like module 65
CHY zinc finger-like Zinc hairpin stack 63
POZ domain Galactose oxidase, central domain 63
Band 7/SPFH domain SCP-like 62
Nucleic acid-binding proteins "Winged helix" DNA-binding domain 63
WWE domain Hect, E3 ligase catalytic domain 63
Ankyrin repeat Second domain of FERM 62
Nucleotidyltransferase Retrovirus zinc finger-like domains 65
Immunoglobulin BPTI-like 64
PurM C-terminal domain-like Formyltransferase 62
GFP-like YWTD domain 65
Oxidoreductase molybdopterin-binding domain E set domains 61
DEATH domain WD40 repeat-like 62
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 64
Nucleic acid-binding proteins BRCT domain 63
THUMP domain-like S-adenosyl-L-methionine-dependent methyltransferases 62
RING/U-box Trimerization domain of TRAF 64
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 61
Protein kinase-like (PK-like) L27 domain 62
TPR-like P-loop containing nucleoside triphosphate hydrolases 64
Ribonuclease H-like Ribonuclease H-like 64
PR-1-like LCCL domain 63
SWIB/MDM2 domain SWIB/MDM2 domain 64
Galactose mutarotase-like Galactose mutarotase-like 65
GST C-terminal domain-like ValRS/IleRS/LeuRS editing domain 62
Aconitase iron-sulfur domain LeuD/IlvD-like 62
ARM repeat POZ domain 63
ARM repeat WWE domain 63
LDL receptor-like module Family A G protein-coupled receptor-like 64
PHM/PNGase F NHL repeat 62
P-loop containing nucleoside triphosphate hydrolases TGS-like 61
Metalloproteases ("zincins"), catalytic domain Metalloproteases ("zincins"), catalytic domain 64
CCHHC domain Acyl-CoA N-acyltransferases (Nat) 62
Retrovirus zinc finger-like domains RING/U-box 64
EF-hand Rhomboid-like 63
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 62
Cysteine-rich domain SH3-domain 63
Eukaryotic type KH-domain (KH-domain type I) RING/U-box 62
DUSP-like Ubiquitin-like 63
FF domain GTPase activation domain, GAP 61
Immunoglobulin DBL homology domain (DH-domain) 65
Cadherin-like Dystroglycan, domain 2 61
LCCL domain LCCL domain 63
DNase I-like GTPase activation domain, GAP 61
UBA-like XPC-binding domain 64
Peptidylarginine deiminase Pad4, middle domain Pentein 61
SPOC domain-like SAP domain 61
P-loop containing nucleoside triphosphate hydrolases RuvA domain 2-like 63
TPR-like CAD & PB1 domains 62
HSP20-like chaperones TPR-like 62
SAM/Pointed domain P-loop containing nucleoside triphosphate hydrolases 62
UBC-like NAD(P)-binding Rossmann-fold domains 61
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 61
vWA-like SAP domain 61
DNA breaking-rejoining enzymes Eukaryotic DNA topoisomerase I, dispensable insert domain 63
PDZ domain-like GTPase activation domain, GAP 63
FYVE/PHD zinc finger S-adenosyl-L-methionine-dependent methyltransferases 61
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 61
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 64
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 61
Carbonic anhydrase Fibronectin type III 62
Cytochrome b5-like heme/steroid binding domain Oxidoreductase molybdopterin-binding domain 61
Zinc hairpin stack RING/U-box 63
FMT C-terminal domain-like ACP-like 61
L domain-like UBA-like 61
Cytochrome b5-like heme/steroid binding domain E set domains 61
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 63
EF-hand DBL homology domain (DH-domain) 63
Doublecortin (DC) Protein kinase-like (PK-like) 62
N-terminal domain of cbl (N-cbl) EF-hand 63
Frizzled cysteine-rich domain Frizzled cysteine-rich domain 64
WD40 repeat-like SNARE fusion complex 63
Cytidine deaminase-like Cytidine deaminase-like 62
PriA/YqbF domain GINS helical bundle-like 62
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 62
Bet v1-like HAD-like 62
PX domain Retrovirus zinc finger-like domains 64
ACP-like ALDH-like 61
Elafin-like Fibronectin type III 65
P-loop containing nucleoside triphosphate hydrolases Nucleotidylyl transferase 62
DEATH domain PDZ domain-like 63
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 62
Periplasmic binding protein-like II Periplasmic binding protein-like II 61
Cupredoxins Pentein 61
Initiation factor IF2/eIF5b, domain 3 Translation proteins 63
P-loop containing nucleoside triphosphate hydrolases POZ domain 62
EGF/Laminin Kringle-like 64
Immunoglobulin PH domain-like 65
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain HIT/MYND zinc finger-like 65
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 63
Trefoil (Trans)glycosidases 64
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 61
N-terminal domain of cbl (N-cbl) RING/U-box 63
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 62
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 62
Cupredoxins Peptidylarginine deiminase Pad4, middle domain 61
WD40 repeat-like SOCS box-like 62
PUA domain-like Ribosomal protein S5 domain 2-like 62
UDP-Glycosyltransferase/glycogen phosphorylase Actin-like ATPase domain 62
Clavaminate synthase-like Tudor/PWWP/MBT 62
Acyl-CoA binding protein ClpP/crotonase 62
SAM/Pointed domain Bet v1-like 62
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 62
UBC-like LDH C-terminal domain-like 61
L domain-like DNase I-like 62
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 61
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 63
Endosomal sorting complex assembly domain VPS28 C-terminal domain-like 61
Quinoprotein alcohol dehydrogenase-like Protein kinase-like (PK-like) 63
CCCH zinc finger Tudor/PWWP/MBT 61
Calponin-homology domain, CH-domain GTPase activation domain, GAP 63
cAMP-binding domain-like Protein kinase-like (PK-like) 52
Serine protease inhibitors AbfB domain 53
gamma-Crystallin-like Ricin B-like lectins 51
Carbamoyl phosphate synthetase, small subunit N-terminal domain PreATP-grasp domain 53
RuvA domain 2-like RuvA domain 2-like 53
Cysteine proteinases Galactose-binding domain-like 51
Histone-fold DBL homology domain (DH-domain) 52
P-loop containing nucleoside triphosphate hydrolases RNase III domain-like 52
Cysteine-rich domain SAM/Pointed domain 52
Quinoprotein alcohol dehydrogenase-like PH domain-like 52
UBC-like UBC-like 53
NAD kinase/diacylglycerol kinase-like SAM/Pointed domain 52
(Phosphotyrosine protein) phosphatases II Chaperone J-domain 53
Quinoprotein alcohol dehydrogenase-like GTPase activation domain, GAP 52
RUN domain-like RUN domain-like 51
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 51
DNA-binding domain Bromodomain 52
Frizzled cysteine-rich domain TIMP-like 52
SAICAR synthase-like N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 51
C-terminal, gelsolin-like domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 53
Tudor/PWWP/MBT Galactose-binding domain-like 53
Heme-dependent peroxidases Ferredoxin reductase-like, C-terminal NADP-linked domain 52
Acetyl-CoA synthetase-like Quinoprotein alcohol dehydrogenase-like 52
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 51
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 53
Arginase/deacetylase Arginase/deacetylase 52
Glucocorticoid receptor-like (DNA-binding domain) VPS9 domain 51
L domain-like Actin depolymerizing proteins 55
BRCT domain DBL homology domain (DH-domain) 51
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor Transcription factor IIA (TFIIA), alpha-helical domain 52
PUG domain-like Galactose-binding domain-like 51
Histone-fold PH domain-like 52
Nucleic acid-binding proteins TPR-like 53
Periplasmic binding protein-like I Nucleotide cyclase 53
F-box domain SMI1/KNR4-like 53
C2 domain (Calcium/lipid-binding domain, CaLB) Chaperone J-domain 53
Ankyrin repeat RCC1/BLIP-II 53
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 52
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 52
PAZ domain RNase III domain-like 52
Frizzled cysteine-rich domain SRCR-like 53
PH domain-like Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain 51
LDL receptor-like module Fibronectin type III 55
Cysteine proteinases Ribonuclease H-like 51
R3H domain RNA-binding domain, RBD 51
Plakin repeat GAS2 domain-like 54
CCCH zinc finger beta-beta-alpha zinc fingers 53
POZ domain A DNA-binding domain in eukaryotic transcription factors 51
Histone-fold Ras GEF 52
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 53
HR1 repeat Protein kinase-like (PK-like) 53
PYP-like sensor domain (PAS domain) Protein kinase-like (PK-like) 51
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 51
Plakin repeat EF-hand 54
Heme-dependent peroxidases EF-hand 52
ARM repeat Zn-dependent exopeptidases 51
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 53
Periplasmic binding protein-like I Protein kinase-like (PK-like) 53
NAD(P)-binding Rossmann-fold domains Citrate synthase 52
Ubiquitin-like Ankyrin repeat 54
Galactose-binding domain-like Mib/herc2 domain-like 53
Glutathione synthetase ATP-binding domain-like Citrate synthase 52
Fibronectin type III Ankyrin repeat 52
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment Eukaryotic DNA topoisomerase I, dispensable insert domain 52
F-box domain Pectin lyase-like 53
G protein-binding domain G protein-binding domain 51
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 51
Formiminotransferase domain of formiminotransferase-cyclodeaminase. Methenyltetrahydrofolate cyclohydrolase-like 52
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 51
Histone-fold ARM repeat 52
PreATP-grasp domain Methylglyoxal synthase-like 53
Ricin B-like lectins Fibronectin type III 55
Calponin-homology domain, CH-domain WW domain 52
WD40 repeat-like SAM/Pointed domain 51
Ankyrin repeat Hect, E3 ligase catalytic domain 53
Protein kinase-like (PK-like) Rhodanese/Cell cycle control phosphatase 51
HSP20-like chaperones Translation proteins 53
RUN domain-like PH domain-like 52
C2 domain (Calcium/lipid-binding domain, CaLB) Eferin C-derminal domain-like 52
ARM repeat UBA-like 53
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 53
RING/U-box SH3-domain 52
TRAF domain-like NRDP1 C-terminal domain-like 52
Ankyrin repeat PDZ domain-like 52
PUG domain-like Cysteine proteinases 51
Tudor/PWWP/MBT P-loop containing nucleoside triphosphate hydrolases 53
DBL homology domain (DH-domain) Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 54
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 51
RNI-like Toll/Interleukin receptor TIR domain 54
E set domains Protein kinase-like (PK-like) 51
ACP-like Quinoprotein alcohol dehydrogenase-like 52
tRNA-binding arm Class II aaRS and biotin synthetases 53
WD40 repeat-like Bromodomain 52
UBA-like Tudor/PWWP/MBT 51
Immunoglobulin 3-carboxy-cis,cis-mucoante lactonizing enzyme 52
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 53
BAR/IMD domain-like SH2 domain 52
Formiminotransferase domain of formiminotransferase-cyclodeaminase. Formiminotransferase domain of formiminotransferase-cyclodeaminase. 52
Nucleotidylyl transferase Ribosomal protein L25-like 54
Calponin-homology domain, CH-domain RING/U-box 52
L domain-like P-loop containing nucleoside triphosphate hydrolases 54
Myosin rod fragments Eferin C-derminal domain-like 52
FnI-like domain Trypsin-like serine proteases 53
Concanavalin A-like lectins/glucanases C-type lectin-like 54
EF-hand Dimeric alpha+beta barrel 53
Tropomyosin Tropomyosin 54
DNA-binding domain FYVE/PHD zinc finger 52
Surp module (SWAP domain) ENTH/VHS domain 52
HAD-like alpha/beta-Hydrolases 51
Kringle-like C-type lectin-like 54
WW domain Quinoprotein alcohol dehydrogenase-like 52
Mannose 6-phosphate receptor domain Mannose 6-phosphate receptor domain 55
TPR-like Chaperone J-domain 53
SMAD/FHA domain RING/U-box 53
Cysteine proteinases C2 domain (Calcium/lipid-binding domain, CaLB) 51
Aminoacid dehydrogenase-like, N-terminal domain P-loop containing nucleoside triphosphate hydrolases 51
C-terminal, gelsolin-like domain of Sec23/24 VHP, Villin headpiece domain 53
RING/U-box PDZ domain-like 53
Glutathione synthetase ATP-binding domain-like NAD(P)-binding Rossmann-fold domains 52
WD40 repeat-like SH3-domain 53
Thioredoxin-like Six-hairpin glycosidases 53
Kazal-type serine protease inhibitors SRCR-like 53
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 53
FAD/NAD(P)-binding domain EF-hand 52
Acetyl-CoA synthetase-like ACP-like 52
Calpain large subunit, middle domain (domain III) C2 domain (Calcium/lipid-binding domain, CaLB) 51
Voltage-gated potassium channels (Phosphotyrosine protein) phosphatases II 51
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 53
LEM domain LEM domain 51
P-loop containing nucleoside triphosphate hydrolases RNA-binding domain, RBD 52
Protein kinase-like (PK-like) WD40 repeat-like 55
Tudor/PWWP/MBT CCHHC domain 52
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 53
BRCT domain PH domain-like 51
Kringle-like Hemopexin-like domain 52
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 52
ArfGap/RecO-like zinc finger SH3-domain 52
POZ domain Leucine zipper domain 51
P-loop containing nucleoside triphosphate hydrolases Fzo-like conserved region 52
Galactose-binding domain-like Hect, E3 ligase catalytic domain 53
Cyclophilin-like RNA-binding domain, RBD 53
SH3-domain ARM repeat 52
WD40 repeat-like Ribonuclease H-like 51
Glucocorticoid receptor-like (DNA-binding domain) Ribonuclease H-like 53
EGF/Laminin EF-hand 51
DBL homology domain (DH-domain) DBL homology domain (DH-domain) 54
Protein kinase-like (PK-like) Ypt/Rab-GAP domain of gyp1p 51
Frizzled cysteine-rich domain Trypsin-like serine proteases 53
FAD-linked reductases, C-terminal domain EF-hand 52
Colipase-like Colipase-like 51
Calponin-homology domain, CH-domain PDZ domain-like 51
RNA-binding domain, RBD SET domain 51
Ricin B-like lectins Kringle-like 54
Heme-dependent peroxidases Riboflavin synthase domain-like 52
WD40 repeat-like Cysteine proteinases 51
Immunoglobulin Growth factor receptor domain 53
Succinyl-CoA synthetase domains NAD(P)-binding Rossmann-fold domains 52
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 52
MFS general substrate transporter occludin/ELL-like 51
Spermadhesin, CUB domain Kelch motif 54
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 52
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 52
Calponin-homology domain, CH-domain RGC domain-like 52
Class I glutamine amidotransferase-like PreATP-grasp domain 53
SH2 domain RING/U-box 52
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 52
SMI1/KNR4-like ApaG-like 53
PreATP-grasp domain PreATP-grasp domain 53
ISP domain FAD/NAD(P)-binding domain 52
Ankyrin repeat Actin-like ATPase domain 51
CAD & PB1 domains PDZ domain-like 51
P-loop containing nucleoside triphosphate hydrolases PAZ domain 52
ATP-dependent DNA ligase DNA-binding domain BRCT domain 52
P-loop containing nucleoside triphosphate hydrolases dsRNA-binding domain-like 52
C-type lectin-like Lipase/lipooxygenase domain (PLAT/LH2 domain) 52
BRCT domain Homeodomain-like 51
N-terminal domain of cbl (N-cbl) SH2 domain 52
YVTN repeat-like/Quinoprotein amine dehydrogenase WD40 repeat-like 55
Plexin repeat Protein kinase-like (PK-like) 51
Voltage-gated potassium channels C2 domain (Calcium/lipid-binding domain, CaLB) 51
WW domain NAD(P)-binding Rossmann-fold domains 51
Second domain of FERM SH2 domain 53
ARM repeat Cullin homology domain 42
Outer arm dynein light chain 1 L domain-like 44
LCCL domain Galactose-binding domain-like 41
DBL homology domain (DH-domain) BAR/IMD domain-like 44
Carbamoyl phosphate synthetase, small subunit N-terminal domain Methylglyoxal synthase-like 42
Glycerol-3-phosphate (1)-acyltransferase EF-hand 41
Ras GEF C2 domain (Calcium/lipid-binding domain, CaLB) 42
PDZ domain-like Flavoproteins 42
Galactose-binding domain-like Carboxypeptidase regulatory domain-like 43
UBA-like SH3-domain 41
Clavaminate synthase-like RNI-like 42
Kazal-type serine protease inhibitors LDL receptor-like module 42
L domain-like SAM/Pointed domain 41
Class I glutamine amidotransferase-like Carbamoyl phosphate synthetase, large subunit connection domain 42
Thiolase-like SCP-like 42
Spermadhesin, CUB domain Family A G protein-coupled receptor-like 41
Ubiquitin-like XPC-binding domain 42
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 42
Peptidase/esterase 'gauge' domain WD40 repeat-like 42
SET domain RuBisCo LSMT C-terminal, substrate-binding domain 43
PX domain PH domain-like 42
EF-hand Eferin C-derminal domain-like 41
Protein prenylyltransferase Rab geranylgeranyltransferase alpha-subunit, insert domain 42
Tudor/PWWP/MBT 6-phosphogluconate dehydrogenase C-terminal domain-like 42
Kazal-type serine protease inhibitors 3-carboxy-cis,cis-mucoante lactonizing enzyme 41
G protein-binding domain Cysteine-rich domain 44
Plexin repeat Fibronectin type III 41
L domain-like Hormone receptor domain 42
GST C-terminal domain-like S-adenosyl-L-methionine-dependent methyltransferases 41
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 41
XRCC4, N-terminal domain XRCC4, C-terminal oligomerization domain 41
Tudor/PWWP/MBT RING/U-box 43
Spectrin repeat Immunoglobulin 44
Cadherin-like Growth factor receptor domain 44
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 42
Hairpin loop containing domain-like Trypsin-like serine proteases 42
Actin-like ATPase domain AF1104-like 43
ARM repeat beta-beta-alpha zinc fingers 41
CCCH zinc finger Retrovirus zinc finger-like domains 44
TrmE connector domain P-loop containing nucleoside triphosphate hydrolases 42
PH domain-like PP2C-like 42
Metalloproteases ("zincins"), catalytic domain TRAF domain-like 42
PX domain Outer arm dynein light chain 1 41
SAP domain EF-hand 43
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 41
Concanavalin A-like lectins/glucanases Complement control module/SCR domain 44
UBC-like Endosomal sorting complex assembly domain 41
Tropomyosin Smc hinge domain 43
UBA-like Phosphoglycerate mutase-like 41
Elafin-like EGF/Laminin 44
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 41
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 41
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 42
CCCH zinc finger P-loop containing nucleoside triphosphate hydrolases 42
PX domain Phospholipase D/nuclease 42
EF-hand Mannose 6-phosphate receptor domain 41
Quinoprotein alcohol dehydrogenase-like TolB, C-terminal domain 43
HAD-like P-loop containing nucleoside triphosphate hydrolases 41
WD40 repeat-like Tricorn protease domain 2 43
Thioredoxin-like FAD-dependent thiol oxidase 42
"Winged helix" DNA-binding domain GTPase activation domain, GAP 42
Molybdenum cofactor biosynthesis proteins Adenine nucleotide alpha hydrolases-like 42
MOSC N-terminal domain-like PK beta-barrel domain-like 43
CHY zinc finger-like RING/U-box 42
Thioredoxin-like FAD/NAD(P)-binding domain 43
post-HMGL domain-like Single hybrid motif 42
Succinyl-CoA synthetase domains Citrate synthase 41
Ribonuclease H-like RuvA domain 2-like 43
Actin-crosslinking proteins Actin-crosslinking proteins 42
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 42
PH domain-like L domain-like 42
Cysteine proteinases Tudor/PWWP/MBT 42
NagB/RpiA/CoA transferase-like RNA-binding domain, RBD 41
Trefoil Glycosyl hydrolase domain 43
GFP-like EGF/Laminin 43
PDZ domain-like Riboflavin synthase domain-like 42
E set domains P-loop containing nucleoside triphosphate hydrolases 42
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 42
Immunoglobulin Kringle-like 44
EGF/Laminin Calcium-dependent phosphotriesterase 42
Tudor/PWWP/MBT HIV integrase-binding domain 41
TPR-like CCCH zinc finger 43
Carbamoyl phosphate synthetase, small subunit N-terminal domain Glutathione synthetase ATP-binding domain-like 42
PDZ domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 42
F-box domain ApaG-like 42
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 42
Mib/herc2 domain-like Hect, E3 ligase catalytic domain 42
SH3-domain Quinoprotein alcohol dehydrogenase-like 41
PX domain GTPase activation domain, GAP 41
ACT-like ACT-like 42
BPTI-like LDL receptor-like module 42
beta-sandwich domain of Sec23/24 Sm-like ribonucleoproteins 42
LDL receptor-like module Mannose 6-phosphate receptor domain 41
vWA-like CalX-like 41
Sec7 domain ARM repeat 43
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 42
Glucocorticoid receptor-like (DNA-binding domain) beta-beta-alpha zinc fingers 41
SNARE-like SNARE fusion complex 42
PYP-like sensor domain (PAS domain) Positive stranded ssRNA viruses 41
Ubiquitin-like Zn-binding ribosomal proteins 41
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 41
Plexin repeat CalX-like 41
Somatomedin B domain Hemopexin-like domain 42
POZ domain WD40 repeat-like 42
Serine protease inhibitors EGF/Laminin 41
ARID-like ARM repeat 42
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 42
L domain-like RING/U-box 41
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 42
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor Transcription factor IIA (TFIIA), beta-barrel domain 41
beta-beta-alpha zinc fingers P-loop containing nucleoside triphosphate hydrolases 43
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 42
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 41
WD40 repeat-like Ypt/Rab-GAP domain of gyp1p 41
GTPase activation domain, GAP ARM repeat 44
Ras GEF PLC-like phosphodiesterases 42
Histone-fold Histone-fold 44
Rap/Ran-GAP Myosin rod fragments 42
Second domain of FERM DBL homology domain (DH-domain) 42
RNI-like ARM repeat 41
Acid proteases DNA/RNA polymerases 42
PDZ domain-like Nitric oxide (NO) synthase oxygenase domain 42
LDL receptor-like module EF-hand 41
Integrin beta tail domain CalX-like 41
EF-hand 3-carboxy-cis,cis-mucoante lactonizing enzyme 41
Concanavalin A-like lectins/glucanases TRAF domain-like 42
HMG-box Chromo domain-like 42
Tudor/PWWP/MBT NAD(P)-binding Rossmann-fold domains 42
WD40 repeat-like TPR-like 42
I/LWEQ domain alpha-catenin/vinculin-like 42
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 43
Taf5 N-terminal domain-like WD40 repeat-like 42
Lipovitellin-phosvitin complex; beta-sheet shell regions Lipovitellin-phosvitin complex; beta-sheet shell regions 43
HAD-like BRCT domain 42
BRCT domain Ankyrin repeat 43
Complement control module/SCR domain Fibronectin type III 44
NHL repeat YVTN repeat-like/Quinoprotein amine dehydrogenase 41
PH domain-like Phospholipase D/nuclease 42
Protein kinase-like (PK-like) Tricorn protease domain 2 41
PAZ domain dsRNA-binding domain-like 41
PAH2 domain Homeodomain-like 41
Carbamoyl phosphate synthetase, small subunit N-terminal domain Carbamoyl phosphate synthetase, large subunit connection domain 42
HLH, helix-loop-helix DNA-binding domain Positive stranded ssRNA viruses 41
beta-lactamase/transpeptidase-like Ankyrin repeat 42
Metallo-dependent phosphatases Formin homology 2 domain (FH2 domain) 41
SMAD/FHA domain HAD-like 41
SAM/Pointed domain ArfGap/RecO-like zinc finger 43
Kazal-type serine protease inhibitors TIMP-like 44
EF-hand Ubiquitin-like 42
CAD & PB1 domains UBA-like 42
Histone-fold Ankyrin repeat 44
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 42
EGF/Laminin NHL repeat 42
P-loop containing nucleoside triphosphate hydrolases Macro domain-like 43
Plexin repeat Plexin repeat 41
Thioredoxin-like FAD/NAD-linked reductases, dimerisation (C-terminal) domain 43
p53-like transcription factors HLH, helix-loop-helix DNA-binding domain 41
UBC-like UBA-like 41
Nqo1 middle domain-like Nqo1C-terminal domain-like 41
Growth factor receptor domain Trypsin-like serine proteases 42
Galactose-binding domain-like Cullin homology domain 42
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 41
Carboxypeptidase regulatory domain-like YVTN repeat-like/Quinoprotein amine dehydrogenase 41
Activator of Hsp90 ATPase, Aha1 Bet v1-like 41
SH3-domain Phosphoglycerate mutase-like 41
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 41
Translational machinery components L30e-like 42
Nucleic acid-binding proteins eIF2alpha middle domain-like 41
DNA-binding domain DNA-glycosylase 41
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 42
MIT domain MIT domain 42
Spermadhesin, CUB domain Frizzled cysteine-rich domain 42
Galactose-binding domain-like Zn-dependent exopeptidases 43
I/LWEQ domain I/LWEQ domain 42
PLC-like phosphodiesterases Ubiquitin-like 42
EF-hand WD40 repeat-like 44
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 41
Spermadhesin, CUB domain LCCL domain 41
SH2 domain PLC-like phosphodiesterases 41
Histone-fold POZ domain 44
G protein-binding domain PH domain-like 44
"Winged helix" DNA-binding domain Class II aaRS and biotin synthetases 42
Class I glutamine amidotransferase-like Glutathione synthetase ATP-binding domain-like 42
CalX-like Fibronectin type III 41
HSP20-like chaperones ThrRS/AlaRS common domain 42
Class I glutamine amidotransferase-like Methylglyoxal synthase-like 42
EF-hand Immunoglobulin 41
TRAF domain-like Cysteine proteinases 43
UBA-like NSFL1 (p97 ATPase) cofactor p47, SEP domain 42
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 42
Hypothetical protein c14orf129, hspc210 TPR-like 41
beta-sandwich domain of Sec23/24 p53-like transcription factors 42
Nucleic acid-binding proteins SAP domain 43
AXH domain HMG-box 41
Integrin beta tail domain Fibronectin type III 41
ClpS-like "Winged helix" DNA-binding domain 41
RNA-binding domain, RBD Clavaminate synthase-like 42
P-loop containing nucleoside triphosphate hydrolases Quinoprotein alcohol dehydrogenase-like 44
SH3-domain PLC-like phosphodiesterases 41
SET domain Bromodomain 42
Tropomyosin Eferin C-derminal domain-like 41
P-loop containing nucleoside triphosphate hydrolases HAND domain of the nucleosome remodeling ATPase ISWI 41
DEATH domain Toll/Interleukin receptor TIR domain 42
Saposin Metallo-dependent phosphatases 42
Kelch motif EGF/Laminin 43
TPR-like Protein kinase-like (PK-like) 42
Tudor/PWWP/MBT BRCT domain 41
ENTH/VHS domain I/LWEQ domain 42
TSP-1 type 1 repeat BPTI-like 42
NHL repeat Calcium-dependent phosphotriesterase 42
L30e-like alpha/beta knot 42
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 42
TAF(II)230 TBP-binding fragment Bromodomain 41
Kringle-like Protein kinase-like (PK-like) 44
Cysteine-rich DNA binding domain, (DM domain) UBA-like 42
HAND domain of the nucleosome remodeling ATPase ISWI Homeodomain-like 41
PABC (PABP) domain Hect, E3 ligase catalytic domain 42
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 41
Tudor/PWWP/MBT ARM repeat 42
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 41
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 42
EGF/Laminin CalX-like 41
Spermadhesin, CUB domain C-type lectin-like 44
Tudor/PWWP/MBT Cullin homology domain 42
S-adenosyl-L-methionine-dependent methyltransferases CCCH zinc finger 41
TAFH domain-like Histone-fold 41
TSP-1 type 1 repeat Carboxypeptidase regulatory domain-like 31
DEATH domain Concanavalin A-like lectins/glucanases 31
EGF/Laminin Thyroglobulin type-1 domain 32
PKD domain C-type lectin-like 32
SEA domain Concanavalin A-like lectins/glucanases 33
Metallo-dependent phosphatases EF-hand 31
EGF/Laminin Methyl-accepting chemotaxis protein (MCP) signaling domain 32
GLA-domain Kringle-like 32
Molybdenum cofactor biosynthesis proteins MoeA N-terminal region -like 31
Glutathione synthetase ATP-binding domain-like PurM N-terminal domain-like 31
PGBD-like Kringle-like 32
TAZ domain RING/U-box 31
DBL homology domain (DH-domain) VPS9 domain 32
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 31
Growth factor receptor domain PDZ domain-like 31
Ubiquitin-like BAG domain 32
Translation proteins Translation proteins 31
Carboxypeptidase regulatory domain-like Immunoglobulin 31
Calponin-homology domain, CH-domain ARM repeat 33
Chaperone J-domain Nucleotidyltransferase substrate binding subunit/domain 32
FMN-linked oxidoreductases dsRNA-binding domain-like 31
TPR-like HCP-like 33
Phospholipase A2, PLA2 Phospholipase A2, PLA2 31
FLJ32549 domain-like FLJ32549 C-terminal domain-like 31
PreATP-grasp domain PurM C-terminal domain-like 31
POZ domain FYVE/PHD zinc finger 33
Starch-binding domain-like (Phosphotyrosine protein) phosphatases II 31
RuvA domain 2-like Nucleic acid-binding proteins 32
UBA-like Hect, E3 ligase catalytic domain 31
ArfGap/RecO-like zinc finger Ubiquitin-like 33
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit EF-hand 31
Multidrug efflux transporter AcrB transmembrane domain NAD-binding domain of HMG-CoA reductase 31
Tex N-terminal region-like Nucleic acid-binding proteins 32
Ubiquitin-like NAD kinase/diacylglycerol kinase-like 32
EGF/Laminin TNF-like 31
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 32
UBA-like WWE domain 31
HR1 repeat PDZ domain-like 31
Second domain of FERM I/LWEQ domain 31
Immunoglobulin TIMP-like 33
SAM/Pointed domain ADP-ribosylation 33
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 33
CAD & PB1 domains His-Me finger endonucleases 31
Kelch motif Fibronectin type III 32
Ankyrin repeat Galactose-binding domain-like 31
S15/NS1 RNA-binding domain S15/NS1 RNA-binding domain 33
Chaperone J-domain Homeodomain-like 32
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain VPS9 domain 32
PH domain-like alpha-catenin/vinculin-like 31
TROVE domain-like P-loop containing nucleoside triphosphate hydrolases 33
Annexin Annexin 32
Nucleic acid-binding proteins EF-hand 32
USP8 N-terminal domain-like Rhodanese/Cell cycle control phosphatase 32
CalX-like C-type lectin-like 31
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 31
FnI-like domain TSP type-3 repeat 31
Tudor/PWWP/MBT Protein kinase-like (PK-like) 32
Rudiment single hybrid motif PurM C-terminal domain-like 31
Ankyrin repeat L domain-like 33
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 31
Telomeric repeat binding factor (TRF) dimerisation domain Homeodomain-like 31
Growth factor receptor domain TSP type-3 repeat 32
Glucocorticoid receptor-like (DNA-binding domain) SH3-domain 31
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 32
Kix domain of CBP (creb binding protein) Nuclear receptor coactivator interlocking domain 31
Granulin repeat Granulin repeat 33
Radical SAM enzymes Molybdenum cofactor biosynthesis protein C, MoaC 32
RCC1/BLIP-II WD40 repeat-like 32
Rap30/74 interaction domains "Winged helix" DNA-binding domain 32
GST C-terminal domain-like S15/NS1 RNA-binding domain 33
PX domain MIT domain 32
Pseudouridine synthase PUA domain-like 32
ITPase-like "Winged helix" DNA-binding domain 31
Heme-dependent peroxidases FnI-like domain 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Chaperone J-domain 32
Clavaminate synthase-like S-adenosyl-L-methionine-dependent methyltransferases 31
Cap-Gly domain RNI-like 31
Thioredoxin-like Galactose-binding domain-like 31
Rudiment single hybrid motif post-HMGL domain-like 31
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 31
Ubiquitin-like A middle domain of Talin 1 31
DNA/RNA polymerases Zinc finger domain of DNA polymerase-alpha 31
Spermadhesin, CUB domain Cystine-knot cytokines 31
BSD domain-like BSD domain-like 32
PKD domain Lipase/lipooxygenase domain (PLAT/LH2 domain) 32
SAM/Pointed domain Retrovirus zinc finger-like domains 32
F-box domain DBL homology domain (DH-domain) 31
F-box domain P-loop containing nucleoside triphosphate hydrolases 31
TAZ domain Kix domain of CBP (creb binding protein) 31
F-box domain PH domain-like 31
C2 domain (Calcium/lipid-binding domain, CaLB) UBA-like 32
Anthrax protective antigen Pectin lyase-like 32
PH domain-like I/LWEQ domain 31
Family A G protein-coupled receptor-like Family A G protein-coupled receptor-like 32
TSP-1 type 1 repeat TSP type-3 repeat 31
TSP-1 type 1 repeat EGF/Laminin 31
Retrovirus zinc finger-like domains Acid proteases 31
Protein prenylyltransferase L domain-like 32
LDL receptor-like module C-type lectin-like 31
Formate/glycerate dehydrogenase catalytic domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 32
Thioesterase/thiol ester dehydrase-isomerase Bet v1-like 32
TAZ domain Nuclear receptor coactivator interlocking domain 31
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 31
Nucleotidylyl transferase SH2 domain 31
RING/U-box Nuclear receptor coactivator interlocking domain 31
RNA-binding domain, RBD Nucleotidyltransferase 33
Ubiquitin-like alpha-catenin/vinculin-like 31
B-box zinc-binding domain TRAF domain-like 32
Tex N-terminal region-like Ribonuclease H-like 32
ALDH-like ALDH-like 31
SGNH hydrolase SGNH hydrolase 31
Calpain large subunit, middle domain (domain III) Calpain large subunit, middle domain (domain III) 32
Rudiment single hybrid motif Formyltransferase 31
PUA domain-like Nucleotidylyl transferase 31
Glutathione synthetase ATP-binding domain-like Aldolase 31
Flavoproteins Radical SAM enzymes 32
B-box zinc-binding domain P-loop containing nucleoside triphosphate hydrolases 31
F-box domain RCC1/BLIP-II 32
RCC1/BLIP-II PABC (PABP) domain 31
NAD(P)-binding Rossmann-fold domains DHS-like NAD/FAD-binding domain 32
Rap30/74 interaction domains Rap30/74 interaction domains 32
Rhodanese/Cell cycle control phosphatase Cysteine proteinases 32
GST C-terminal domain-like eEF-1beta-like 31
Ribonuclease H-like HRDC-like 32
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 32
SAM/Pointed domain Ubiquitin-like 32
WW domain FKBP-like 31
Ankyrin repeat FYVE/PHD zinc finger 33
BAG domain BAG domain 31
Ribonuclease H-like P-loop containing nucleoside triphosphate hydrolases 32
MIT domain P-loop containing nucleoside triphosphate hydrolases 31
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 32
Immunoglobulin Hormone receptor domain 32
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 31
PreATP-grasp domain Formyltransferase 31
F-box domain YccV-like 31
E set domains Anthrax protective antigen 32
CAD & PB1 domains Cysteine-rich domain 32
Homeodomain-like FAD/NAD(P)-binding domain 32
PreATP-grasp domain Aldolase 31
PX domain SAM/Pointed domain 32
Second domain of FERM alpha-catenin/vinculin-like 31
FAD/NAD(P)-binding domain Nucleotide-binding domain 32
"Winged helix" DNA-binding domain occludin/ELL-like 31
Doublecortin (DC) Ricin B-like lectins 32
Aldolase post-HMGL domain-like 31
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 32
Somatomedin B domain EndoU-like 33
Retrovirus zinc finger-like domains DNA/RNA polymerases 31
Kix domain of CBP (creb binding protein) Bromodomain 31
A middle domain of Talin 1 alpha-catenin/vinculin-like 31
HMA, heavy metal-associated domain Cu,Zn superoxide dismutase-like 31
Growth factor receptor domain Intermediate filament protein, coiled coil region 31
TB module/8-cys domain Kazal-type serine protease inhibitors 32
Aldolase Single hybrid motif 31
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 32
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Nucleotidyltransferase substrate binding subunit/domain 32
CRAL/TRIO domain PapD-like 32
ITPase-like S-adenosyl-L-methionine-dependent methyltransferases 31
Dihydropteroate synthetase-like Methionine synthase activation domain-like 33
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 32
HMG-box P-loop containing nucleoside triphosphate hydrolases 31
Concanavalin A-like lectins/glucanases HCP-like 31
BPTI-like TIMP-like 33
ENTH/VHS domain SH3-domain 33
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 32
CRAL/TRIO domain Protein kinase-like (PK-like) 32
beta-beta-alpha zinc fingers Nucleotidyltransferase 33
PreATP-grasp domain PurM N-terminal domain-like 31
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 31
Kazal-type serine protease inhibitors PDZ domain-like 31
L domain-like FnI-like domain 32
DAK1/DegV-like DhaL-like 31
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 32
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 32
Methyl-accepting chemotaxis protein (MCP) signaling domain Concanavalin A-like lectins/glucanases 32
(Phosphotyrosine protein) phosphatases II DNA ligase/mRNA capping enzyme, catalytic domain 33
MIT domain F-box domain 32
TRAF domain-like PDZ domain-like 32
Calcium-dependent phosphotriesterase Quinoprotein alcohol dehydrogenase-like 32
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 33
MoeA N-terminal region -like MoeA C-terminal domain-like 31
ARM repeat Mib/herc2 domain-like 31
Ankyrin repeat ADP-ribosylation 33
dsRNA-binding domain-like Protein kinase-like (PK-like) 31
Glucocorticoid receptor-like (DNA-binding domain) DNA ligase/mRNA capping enzyme, catalytic domain 33
WD40 repeat-like Cyclophilin-like 32
Cupredoxins Galactose-binding domain-like 32
Pentapeptide repeat-like RNA-binding domain, RBD 32
R3H domain P-loop containing nucleoside triphosphate hydrolases 33
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 31
PIN domain-like Nucleic acid-binding proteins 32
PreATP-grasp domain post-HMGL domain-like 31
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase C-terminal domain-like 32
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 32
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 31
Bromodomain Nuclear receptor coactivator interlocking domain 31
SAP domain Ribonuclease H-like 31
PH domain-like A middle domain of Talin 1 31
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 31
Nucleotidyltransferase Poly A polymerase C-terminal region-like 31
Ribonuclease H-like Nucleic acid-binding proteins 32
RING/U-box Cyclophilin-like 31
Glutathione synthetase ATP-binding domain-like PurM C-terminal domain-like 31
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 31
Formate/glycerate dehydrogenase catalytic domain-like DHS-like NAD/FAD-binding domain 32
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 32
TPR-like RNA-binding domain, RBD 33
HAD-like Protein kinase-like (PK-like) 32
RNI-like Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain 31
Protein kinase-like (PK-like) RCC1/BLIP-II 32
Rudiment single hybrid motif Aldolase 31
PDZ domain-like BAR/IMD domain-like 32
Macro domain-like Zn-dependent exopeptidases 31
A middle domain of Talin 1 I/LWEQ domain 31
N-acetylmuramoyl-L-alanine amidase-like N-acetylmuramoyl-L-alanine amidase-like 32
Tex N-terminal region-like RuvA domain 2-like 32
Ankyrin repeat FabD/lysophospholipase-like 31
WW domain dsRNA-binding domain-like 32
RING/U-box NRDP1 C-terminal domain-like 31
RNI-like Ubiquitin-like 31
Alpha-macroglobulin receptor domain Kazal-type serine protease inhibitors 33
E set domains Pectin lyase-like 32
Rudiment single hybrid motif PurM N-terminal domain-like 31
Ribonuclease H-like Zinc finger domain of DNA polymerase-alpha 31
Serpins Serpins 31
TPR-like PIN domain-like 32
Composite domain of metallo-dependent hydrolases Aspartate/ornithine carbamoyltransferase 32
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 32
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase NM domain-like 32
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 31
RCC1/BLIP-II Galactose-binding domain-like 32
Homeodomain-like FAD-linked reductases, C-terminal domain 32
"Winged helix" DNA-binding domain dsRNA-binding domain-like 32
Second domain of FERM A middle domain of Talin 1 31
Sialidases Sialidases 32
TSP-1 type 1 repeat Complement control module/SCR domain 32
dsRNA-binding domain-like R3H domain 31
Periplasmic binding protein-like I Periplasmic binding protein-like I 32
"Winged helix" DNA-binding domain RING/U-box 31
TAZ domain Bromodomain 31
Concanavalin A-like lectins/glucanases TSP-1 type 1 repeat 31
PDZ domain-like Formin homology 2 domain (FH2 domain) 32
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 31
Nucleotide-diphospho-sugar transferases Nucleotide-diphospho-sugar transferases 32
FYVE/PHD zinc finger Hect, E3 ligase catalytic domain 31
RCC1/BLIP-II RCC1/BLIP-II 33
Kazal-type serine protease inhibitors BPTI-like 33
BAR/IMD domain-like BAR/IMD domain-like 31
Staphylococcal nuclease Protein kinase-like (PK-like) 32
WD40 repeat-like FYVE/PHD zinc finger 33
Sec63 N-terminal domain-like E set domains 32
C-type lectin-like Growth factor receptor domain 33
Epsilon subunit of F1F0-ATP synthase N-terminal domain Epsilon subunit of F1F0-ATP synthase C-terminal domain 31
Ubiquitin-like I/LWEQ domain 31
SET domain HIT/MYND zinc finger-like 33
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 31
YWTD domain Fibronectin type III 32
Spectrin repeat Protein kinase-like (PK-like) 32
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 31
Glutathione synthetase ATP-binding domain-like Formyltransferase 31
PurM N-terminal domain-like Formyltransferase 31
Hedgehog/DD-peptidase Hedgehog/intein (Hint) domain 32
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 33
Nucleic acid-binding proteins Retrovirus zinc finger-like domains 31
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 31
Concanavalin A-like lectins/glucanases SOCS box-like 31
Glucocorticoid receptor-like (DNA-binding domain) ATP-dependent DNA ligase DNA-binding domain 33
Molybdenum cofactor biosynthesis proteins Molybdenum cofactor biosynthesis proteins 31
TSP-1 type 1 repeat Spermadhesin, CUB domain 32
Protein kinase-like (PK-like) G protein-binding domain 33
UBA-like Protein kinase-like (PK-like) 31
E set domains AMPKBI-like 31
RNA-binding domain, RBD PAP/OAS1 substrate-binding domain 33
Ran binding protein zinc finger-like UBA-like 32
Kix domain of CBP (creb binding protein) RING/U-box 31
TAZ domain TAZ domain 31
TPR-like beta-beta-alpha zinc fingers 32
beta-beta-alpha zinc fingers PAP/OAS1 substrate-binding domain 33
Myosin rod fragments Lamin A/C globular tail domain 32
(Trans)glycosidases Acyl-CoA N-acyltransferases (Nat) 31
Saposin SGNH hydrolase 31
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 32
PH domain-like Bet v1-like 32
Ypt/Rab-GAP domain of gyp1p Cysteine proteinases 32
Multidrug efflux transporter AcrB transmembrane domain Substrate-binding domain of HMG-CoA reductase 31
L domain-like WD40 repeat-like 33
Zn-dependent exopeptidases Zn-dependent exopeptidases 33
PUG domain-like Ubiquitin-like 31
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 31
Zinc-binding domain of translation initiation factor 2 beta ARM repeat 31
BRCT domain post-AAA+ oligomerization domain-like 21
Nucleic acid-binding proteins BRCA2 tower domain 21
Immunoglobulin Heme-dependent peroxidases 21
Kazal-type serine protease inhibitors FnI-like domain 22
WD40 repeat-like Tubby C-terminal domain-like 22
CCCH zinc finger RNA-binding domain, RBD 21
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 22
BRCT domain Domain of poly(ADP-ribose) polymerase 22
PDZ domain-like PX domain 21
L domain-like PKD domain 21
Galactose-binding domain-like BRCT domain 21
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 21
UBC-like Protein kinase-like (PK-like) 22
Glutathione synthetase ATP-binding domain-like Metallo-dependent hydrolases 21
Bcr-Abl oncoprotein oligomerization domain PH domain-like 21
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 21
Glutamine synthetase/guanido kinase GatB/YqeY motif 21
Invasin/intimin cell-adhesion fragments Invasin/intimin cell-adhesion fragments 21
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain Wiscott-Aldrich syndrome protein, WASP, C-terminal domain 22
Methylglyoxal synthase-like Aspartate/ornithine carbamoyltransferase 21
Ubiquitin-like EPT/RTPC-like 21
Ubiquitin-like Chaperone J-domain 21
RCC1/BLIP-II RING/U-box 21
Carbamoyl phosphate synthetase, small subunit N-terminal domain Composite domain of metallo-dependent hydrolases 21
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 22
Dihydropteroate synthetase-like Methionine synthase domain 22
Dipeptidyl peptidase I (cathepsin C), exclusion domain Cysteine proteinases 21
EPT/RTPC-like EPT/RTPC-like 21
Elafin-like TIMP-like 22
PRTase-like Ribulose-phoshate binding barrel 21
CO dehydrogenase flavoprotein C-terminal domain-like CO dehydrogenase molybdoprotein N-domain-like 21
LDL receptor-like module Complement control module/SCR domain 21
PRP4-like WD40 repeat-like 21
L domain-like Lipase/lipooxygenase domain (PLAT/LH2 domain) 21
Bcl-2 inhibitors of programmed cell death RNA-binding domain, RBD 21
Tex N-terminal region-like SH2 domain 21
Glutathione synthetase ATP-binding domain-like Composite domain of metallo-dependent hydrolases 21
Thioredoxin-like ERP29 C domain-like 21
LDL receptor-like module Protein kinase-like (PK-like) 22
Glucocorticoid receptor-like (DNA-binding domain) Putative DNA-binding domain 21
Homocysteine S-methyltransferase Methionine synthase activation domain-like 22
RuvA domain 2-like SH2 domain 21
PUG domain-like Ran binding protein zinc finger-like 21
TRAF domain-like F-box domain 21
RNA-binding domain, RBD Tudor/PWWP/MBT 22
RNA-binding domain, RBD Surp module (SWAP domain) 21
SEA domain Immunoglobulin 21
Protein kinase-like (PK-like) Myosin phosphatase inhibitor 17kDa protein, CPI-17 22
Kelch motif C-type lectin-like 22
E set domains Galactose-binding domain-like 21
Cullin homology domain RING/U-box 21
Kringle-like HCP-like 22
"Winged helix" DNA-binding domain HRDC-like 22
BRCT domain ADP-ribosylation 22
Nucleic acid-binding proteins SH2 domain 21
PF0523-like PF0523-like 21
L domain-like Ubiquitin-like 21
PLP-dependent transferases PLP-dependent transferases 22
PH domain-like BSD domain-like 21
Tudor/PWWP/MBT DNA repair protein MutS, domain I 22
PreATP-grasp domain Composite domain of metallo-dependent hydrolases 21
Sec63 N-terminal domain-like Ribonuclease H-like 21
L domain-like DEATH domain 21
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 21
C2 domain (Calcium/lipid-binding domain, CaLB) Regulator of G-protein signaling, RGS 21
Arginase/deacetylase RING/U-box 21
FAD-binding/transporter-associated domain-like CO dehydrogenase molybdoprotein N-domain-like 21
RNI-like Family A G protein-coupled receptor-like 21
Mitochondrial carrier Mitochondrial carrier 21
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 22
DNase I-like SAM/Pointed domain 22
Six-hairpin glycosidases Six-hairpin glycosidases 21
GST C-terminal domain-like Methionyl-tRNA synthetase (MetRS), Zn-domain 22
Macro domain-like CRAL/TRIO domain 21
Cysteine proteinases EPT/RTPC-like 21
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 22
FYVE/PHD zinc finger Rabenosyn-5 Rab-binding domain-like 21
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 22
HBS1-like domain Translation proteins 22
Carbamate kinase-like ALDH-like 21
DEATH domain HIN-2000 domain-like 21
GLA-domain Concanavalin A-like lectins/glucanases 22
Ankyrin repeat Tropomyosin 21
PurM C-terminal domain-like Class I glutamine amidotransferase-like 22
L domain-like Heme-dependent peroxidases 21
beta-beta-alpha zinc fingers Formin homology 2 domain (FH2 domain) 21
PreATP-grasp domain Aspartate/ornithine carbamoyltransferase 21
Class I glutamine amidotransferase-like Metallo-dependent hydrolases 21
alpha/beta-Hydrolases alpha/beta-Hydrolases 22
Galactose-binding domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 21
ENTH/VHS domain FYVE/PHD zinc finger 21
PH domain-like Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Tryptophan synthase beta subunit-like PLP-dependent enzymes 21
GMP synthetase C-terminal dimerisation domain GMP synthetase C-terminal dimerisation domain 21
Metalloproteases ("zincins"), catalytic domain Immunoglobulin 21
Seven-hairpin glycosidases PA domain 22
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 21
Eukaryotic type KH-domain (KH-domain type I) P-loop containing nucleoside triphosphate hydrolases 21
Protein kinase-like (PK-like) Class II aaRS and biotin synthetases 22
Clavaminate synthase-like FabD/lysophospholipase-like 21
SH2 domain SAM/Pointed domain 22
SWIB/MDM2 domain eIF1-like 22
Class I glutamine amidotransferase-like Aspartate/ornithine carbamoyltransferase 21
CRAL/TRIO domain CRAL/TRIO domain 21
DNA-binding domain Tudor/PWWP/MBT 21
Nicotinic receptor ligand binding domain-like Nicotinic receptor ligand binding domain-like 22
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 21
Immunoglobulin Retroviral matrix proteins 21
SPOC domain-like C-terminal domain of Ku80 21
E set domains Glycosyl hydrolase domain 22
Protein kinase-like (PK-like) Chaperone J-domain 21
P-loop containing nucleoside triphosphate hydrolases Calcium-dependent phosphotriesterase 22
RING/U-box Prefoldin 22
ARM repeat HMA, heavy metal-associated domain 22
SAND domain-like HIT/MYND zinc finger-like 22
Spectrin repeat Fibronectin type III 21
RUN domain-like Supernatant protein factor (SPF), C-terminal domain 21
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 21
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases S15/NS1 RNA-binding domain 22
Class II MHC-associated invariant chain ectoplasmic trimerization domain Thyroglobulin type-1 domain 22
Eukaryotic type KH-domain (KH-domain type I) Prokaryotic type KH domain (KH-domain type II) 21
MFS general substrate transporter alpha/beta knot 21
Protein kinase-like (PK-like) (Phosphotyrosine protein) phosphatases II 21
DEATH domain SH3-domain 21
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain SET domain 21
Nucleotidyltransferase Ubiquitin-like 22
Outer arm dynein light chain 1 Toll/Interleukin receptor TIR domain 21
CRAL/TRIO domain (Phosphotyrosine protein) phosphatases II 21
P-loop containing nucleoside triphosphate hydrolases DNA/RNA polymerases 21
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 21
Methylglyoxal synthase-like Cytidine deaminase-like 21
Retrovirus capsid dimerization domain-like Ribonuclease H-like 22
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 21
DUSP-like EPT/RTPC-like 21
PUG domain-like RING/U-box 21
PH domain-like Wiscott-Aldrich syndrome protein, WASP, C-terminal domain 22
Staphylococcal nuclease Staphylococcal nuclease 22
Glucocorticoid receptor-like (DNA-binding domain) BRCT domain 22
Bcr-Abl oncoprotein oligomerization domain C2 domain (Calcium/lipid-binding domain, CaLB) 21
FYSH domain Hypothetical protein AF0491, middle domain 21
Dcp2 domain-like Nudix 21
Ribosomal protein L25-like S15/NS1 RNA-binding domain 22
Ricin B-like lectins (Phosphotyrosine protein) phosphatases II 22
FAS1 domain C-type lectin-like 22
Thyroglobulin type-1 domain alpha/beta-Hydrolases 22
Ribonuclease H-like SH2 domain 21
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 22
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 22
EF-hand DUSP-like 22
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 21
Ubiquitin-like TPR-like 22
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 22
DBL homology domain (DH-domain) "Winged helix" DNA-binding domain 22
CAD & PB1 domains C-terminal domain of DFF45/ICAD (DFF-C domain) 21
P-loop containing nucleoside triphosphate hydrolases Ran binding protein zinc finger-like 21
Glucocorticoid receptor-like (DNA-binding domain) Myosin phosphatase inhibitor 17kDa protein, CPI-17 22
SH2 domain DNase I-like 22
beta-beta-alpha zinc fingers S-adenosyl-L-methionine-dependent methyltransferases 22
P-loop containing nucleoside triphosphate hydrolases PRTase-like 21
TRAF domain-like EGF/Laminin 21
Chaperone J-domain CSL zinc finger 21
PUA domain-like eIF1-like 22
vWA-like C-terminal domain of Ku80 21
DNA polymerase beta, N-terminal domain-like Restriction endonuclease-like 22
FYVE/PHD zinc finger GroEL-intermediate domain like 22
ARM repeat L domain-like 22
BRCA2 helical domain Nucleic acid-binding proteins 21
CalX-like Concanavalin A-like lectins/glucanases 22
Galactose oxidase, central domain Galactose oxidase, central domain 21
CRAL/TRIO domain Fibronectin type III 21
Carbamoyl phosphate synthetase, large subunit connection domain Composite domain of metallo-dependent hydrolases 21
Macro domain-like WWE domain 22
Carbamoyl phosphate synthetase, small subunit N-terminal domain Aspartate/ornithine carbamoyltransferase 21
DHH phosphoesterases CRAL/TRIO domain 21
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 22
Concanavalin A-like lectins/glucanases Protein kinase-like (PK-like) 22
TPR-like Cyclophilin-like 22
Sec63 N-terminal domain-like DNA/RNA polymerases 21
Ankyrin repeat LEM domain 22
BRCT domain Lesion bypass DNA polymerase (Y-family), little finger domain 21
Frizzled cysteine-rich domain Zn-dependent exopeptidases 21
Acyl-CoA N-acyltransferases (Nat) Bromodomain 21
Protein kinase-like (PK-like) RNA-binding domain, RBD 21
CBS-domain pair cAMP-binding domain-like 21
P-loop containing nucleoside triphosphate hydrolases RGC domain-like 22
Chaperone J-domain Chaperone J-domain 21
WD40 repeat-like UBC-like 21
P-loop containing nucleoside triphosphate hydrolases HRDC-like 22
F-box domain YVTN repeat-like/Quinoprotein amine dehydrogenase 21
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 21
Glutaminase/Asparaginase Ankyrin repeat 21
Kazal-type serine protease inhibitors SEA domain 22
CRAL/TRIO N-terminal domain PapD-like 21
BAH domain Homeodomain-like 21
Metallo-dependent hydrolases Aspartate/ornithine carbamoyltransferase 21
L domain-like Soluble quinoprotein glucose dehydrogenase 21
YWTD domain Protein kinase-like (PK-like) 21
BRCT domain DNA/RNA polymerases 21
Arp2/3 complex subunits Arp2/3 complex subunits 21
UBA-like P-loop containing nucleoside triphosphate hydrolases 22
Carbamoyl phosphate synthetase, small subunit N-terminal domain Metallo-dependent hydrolases 21
Methionine synthase domain Methionine synthase activation domain-like 22
PDZ domain-like Myosin phosphatase inhibitor 17kDa protein, CPI-17 22
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 21
R3H domain Ankyrin repeat 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 22
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain NagB/RpiA/CoA transferase-like 21
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 21
RNA-binding domain, RBD PWI domain 21
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 22
HAD-like Acyl-CoA dehydrogenase C-terminal domain-like 21
BRCT domain P-loop containing nucleoside triphosphate hydrolases 21
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 22
YaeB-like YaeB-like 21
EF-hand FnI-like domain 22
PP2C-like P-loop containing nucleoside triphosphate hydrolases 21
GST C-terminal domain-like Ribosomal protein L25-like 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 21
Spermadhesin, CUB domain TIMP-like 21
beta-sandwich domain of Sec23/24 beta-sandwich domain of Sec23/24 21
PX domain TPR-like 21
C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase WD40 repeat-like 22
RING/U-box beta-beta-alpha zinc fingers 21
WD40 repeat-like TNF-like 22
Ubiquitin-like Nucleotidyltransferase substrate binding subunit/domain 21
Ubiquitin-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 21
B-box zinc-binding domain WD40 repeat-like 22
TNF-like Tubby C-terminal domain-like 22
Galactose oxidase, central domain FYVE/PHD zinc finger 21
alpha/beta knot Nucleic acid-binding proteins 21
PUG domain-like UBA-like 21
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 21
Lipocalins BPTI-like 21
ARM repeat Homeodomain-like 21
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 21
Nucleotide-diphospho-sugar transferases ARM repeat 21
HBS1-like domain EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 22
Bcr-Abl oncoprotein oligomerization domain GTPase activation domain, GAP 21
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 21
E set domains Hect, E3 ligase catalytic domain 21
Elafin-like Growth factor receptor domain 22
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 21
TNF-like TNF-like 22
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 21
HAD-like Acyl-CoA dehydrogenase NM domain-like 21
TPR-like UBA-like 22
E set domains (Trans)glycosidases 22
Nitrous oxide reductase, N-terminal domain WD40 repeat-like 21
Bcr-Abl oncoprotein oligomerization domain DBL homology domain (DH-domain) 21
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 21
ARM repeat EF-hand 22
FAD-binding/transporter-associated domain-like Molybdenum cofactor-binding domain 21
BRCA2 helical domain BRCA2 tower domain 21
SAM/Pointed domain Toll/Interleukin receptor TIR domain 22
P-loop containing nucleoside triphosphate hydrolases vWA-like 22
UBA-like CCCH zinc finger 22
FYVE/PHD zinc finger GroEL apical domain-like 22
Clavaminate synthase-like C2 domain (Calcium/lipid-binding domain, CaLB) 21
"Winged helix" DNA-binding domain GroEL apical domain-like 22
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 21
Kazal-type serine protease inhibitors Concanavalin A-like lectins/glucanases 22
Cadherin-like Protein kinase-like (PK-like) 21
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 22
F-box domain Sec7 domain 21
HBS1-like domain P-loop containing nucleoside triphosphate hydrolases 22
Cytochrome P450 Cytochrome P450 21
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 21
Elafin-like Immunoglobulin 22
TPR-like Metallo-dependent phosphatases 21
SNARE-like P-loop containing nucleoside triphosphate hydrolases 21
GLA-domain Growth factor receptor domain 22
GTF2I-like repeat Ribonuclease H-like 21
Tudor/PWWP/MBT DNA repair protein MutS, domain III 22
UBA-like Thioredoxin-like 21
Ankyrin repeat EF-hand 21
Outer arm dynein light chain 1 RNI-like 21
Ankyrin repeat Nudix 21
TPR-like HIT/MYND zinc finger-like 22
Methylglyoxal synthase-like Metallo-dependent hydrolases 21
TRADD, N-terminal domain DEATH domain 21
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 21
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 21
Elafin-like Kazal-type serine protease inhibitors 22
PH domain-like RING/U-box 22
PreATP-grasp domain Metallo-dependent hydrolases 21
VPS9 domain Ubiquitin-like 22
DEATH domain Tropomyosin 21
Assembly domain of cartilage oligomeric matrix protein Growth factor receptor domain 21
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 21
PRP4-like Functional domain of the splicing factor Prp18 21
CO dehydrogenase flavoprotein C-terminal domain-like Molybdenum cofactor-binding domain 21
P-loop containing nucleoside triphosphate hydrolases Rad50 coiled-coil Zn hook 22
TROVE domain-like WD40 repeat-like 22
DNA clamp DNA clamp 21
EGF/Laminin SEA domain 22
Carbamoyl phosphate synthetase, large subunit connection domain Aspartate/ornithine carbamoyltransferase 21
Metalloproteases ("zincins"), catalytic domain Complement control module/SCR domain 22
NAD(P)-binding Rossmann-fold domains NagB/RpiA/CoA transferase-like 21
4-helical cytokines 4-helical cytokines 21
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 21
"Winged helix" DNA-binding domain E set domains 21
"Winged helix" DNA-binding domain GroEL-intermediate domain like 22
RuvA domain 2-like DNase I-like 21
WD40 repeat-like Calcium-dependent phosphotriesterase 22
Integrin alpha N-terminal domain Growth factor receptor domain 21
Metallo-dependent phosphatases Metallo-dependent phosphatases 21
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 21
Methylglyoxal synthase-like Composite domain of metallo-dependent hydrolases 21
HMA, heavy metal-associated domain Metal cation-transporting ATPase, ATP-binding domain N 21
USP8 N-terminal domain-like Cysteine proteinases 21
Galactose oxidase, central domain WD40 repeat-like 22
Carboxypeptidase regulatory domain-like Calcium-dependent phosphotriesterase 21
Class II aaRS and biotin synthetases Class II aaRS and biotin synthetases 22
Immunoglobulin FnI-like domain 21
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 21
Trimeric LpxA-like enzymes ARM repeat 21
KRAB domain (Kruppel-associated box) Homeodomain-like 21
Trefoil Trefoil 22
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 21
vWA-like Immunoglobulin 22
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) Protein kinase-like (PK-like) 22
Pre-PUA domain PUA domain-like 21
Class I glutamine amidotransferase-like Composite domain of metallo-dependent hydrolases 21
Rhomboid-like UBA-like 21
PUA domain-like SWIB/MDM2 domain 22
EPT/RTPC-like RNA 3'-terminal phosphate cyclase, RPTC, insert domain 21
Rabenosyn-5 Rab-binding domain-like Rabenosyn-5 Rab-binding domain-like 21
Frizzled cysteine-rich domain Carboxypeptidase regulatory domain-like 21
RNA-binding domain, RBD Tricorn protease domain 2 21
FYVE/PHD zinc finger Supernatant protein factor (SPF), C-terminal domain 21
Ubiquitin-like Acid proteases 21
Immunoglobulin GFP-like 22
F-box domain Quinoprotein alcohol dehydrogenase-like 21
EGF/Laminin Prefoldin 21
Glutathione synthetase ATP-binding domain-like Aspartate/ornithine carbamoyltransferase 21
CRAL/TRIO N-terminal domain (Phosphotyrosine protein) phosphatases II 21
Carboxypeptidase regulatory domain-like Carboxypeptidase regulatory domain-like 22
FAS1 domain EGF/Laminin 22
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 21
Rab geranylgeranyltransferase alpha-subunit, insert domain L domain-like 21
SNARE-like Domain of the SRP/SRP receptor G-proteins 21
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 21
HIT-like HIT-like 21
Class II aaRS and biotin synthetases Translation proteins 21
Ubiquitin-like HAD-like 21
Tricorn protease domain 2 TPR-like 22
L domain-like C-type lectin-like 21
TPR-like SET domain 22
FnI-like domain AbfB domain 21
KRAB domain (Kruppel-associated box) Ribonuclease H-like 22
Glucocorticoid receptor-like (DNA-binding domain) Nucleic acid-binding proteins 22
Carbamoyl phosphate synthetase, large subunit connection domain Metallo-dependent hydrolases 21
RCC1/BLIP-II E set domains 21
Concanavalin A-like lectins/glucanases F-box domain 22
Immunoglobulin Caspase-like 21
Chaperone J-domain beta-beta-alpha zinc fingers 21
P-loop containing nucleoside triphosphate hydrolases LigT-like 21
EGF/Laminin Carboxypeptidase regulatory domain-like 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 21
Glucocorticoid receptor-like (DNA-binding domain) ADP-ribosylation 11
DPP6 N-terminal domain-like TPR-like 11
ClpS-like Mitochondrial carrier 11
Kelch motif NHL repeat 11
Mitochondrial cytochrome c oxidase subunit VIa Glu-tRNAGln amidotransferase C subunit 11
Family A G protein-coupled receptor-like Tubulin C-terminal domain-like 11
Protein prenylyltransferase Outer arm dynein light chain 1 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
MIT domain Calpain large subunit, middle domain (domain III) 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Ricin B-like lectins Ricin B-like lectins 11
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 11
Putative DNA-binding domain Cation efflux protein transmembrane domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases NAD(P)-binding Rossmann-fold domains 11
C-terminal domain of adenylylcyclase associated protein Nucleoside diphosphate kinase, NDK 11
ABC transporter transmembrane region Immunoglobulin 11
Aldolase Aldolase 11
NAD(P)-binding Rossmann-fold domains t-snare proteins 11
CRAL/TRIO domain Immunoglobulin 11
PurS-like PurM N-terminal domain-like 11
Cysteine alpha-hairpin motif Cysteine alpha-hairpin motif 11
LEM domain RNA-binding domain, RBD 11
Lipovitellin-phosvitin complex; beta-sheet shell regions ARM repeat 11
Chaperone J-domain RNA-binding domain, RBD 11
YVTN repeat-like/Quinoprotein amine dehydrogenase RING/U-box 11
Nucleotide-binding domain FMN-linked oxidoreductases 11
ARM repeat SAM/Pointed domain 11
S-adenosyl-L-methionine-dependent methyltransferases Kelch motif 11
HSP20-like chaperones Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Surp module (SWAP domain) Ubiquitin-like 11
GST C-terminal domain-like eEF1-gamma domain 11
RING/U-box 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
GroEL apical domain-like SAICAR synthase-like 11
Concanavalin A-like lectins/glucanases SRCR-like 11
RNA-binding domain, RBD Rps17e-like 11
Domain of poly(ADP-ribose) polymerase vWA-like 11
Putative isomerase YbhE Quinoprotein alcohol dehydrogenase-like 11
mRNA decapping enzyme DcpS N-terminal domain HIT-like 11
PurS-like FGAM synthase PurL, linker domain 11
ADP-ribosylation vWA-like 11
YVTN repeat-like/Quinoprotein amine dehydrogenase Putative isomerase YbhE 11
Ankyrin repeat Oxysterol-binding protein-like 11
Tubulin chaperone cofactor A Tubulin chaperone cofactor A 11
His-Me finger endonucleases HIT/MYND zinc finger-like 11
WW domain BAG domain 11
Hypothetical protein c14orf129, hspc210 ARM repeat 11
alpha/beta-Hydrolases Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases PX domain 11
UBA-like SMR domain-like 11
PDZ domain-like Cysteine-rich domain 11
TROVE domain-like Calcium-dependent phosphotriesterase 11
Folate-binding domain TrmE connector domain 11
Homeodomain-like JAB1/MPN domain 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
Dom34/Pelota N-terminal domain-like L30e-like 11
WD40 repeat-like HMG-box 11
GYF domain Chaperone J-domain 11
ARM repeat Toll/Interleukin receptor TIR domain 11
SH2 domain UBA-like 11
RmlC-like cupins RmlC-like cupins 11
L-aspartase-like HRDC-like 11
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 11
PLP-dependent transferases MOSC N-terminal domain-like 11
GLA-domain Tetraspanin 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Putative DNA-binding domain Putative DNA-binding domain 11
Cytochrome b5-like heme/steroid binding domain Riboflavin synthase domain-like 11
Protein kinase-like (PK-like) Intermediate filament protein, coiled coil region 11
Ankyrin repeat WD40 repeat-like 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
PH domain-like Cullin repeat-like 11
Thiolase-like GroES-like 11
ARM repeat Chaperone J-domain 11
Quinoprotein alcohol dehydrogenase-like C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 11
SNARE-like SNARE-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Tudor/PWWP/MBT 11
Aldolase AFP III-like domain 11
Inhibitor of apoptosis (IAP) repeat UBC-like 11
Sm-like ribonucleoproteins Sm-like ribonucleoproteins 11
Cupredoxins Pectin lyase-like 11
PX domain PX domain 11
Cytochrome P450 Trypsin-like serine proteases 11
Metalloproteases ("zincins"), catalytic domain Fibronectin type III 11
Dom34/Pelota N-terminal domain-like Translational machinery components 11
Homocysteine S-methyltransferase Methionine synthase domain 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Ribokinase-like Ribokinase-like 11
Nucleoporin domain HMG-box 11
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit P-loop containing nucleoside triphosphate hydrolases 11
NHL repeat NHL repeat 11
Family A G protein-coupled receptor-like Tubulin nucleotide-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases Polo-box domain 11
PH domain-like RNI-like 11
P-loop containing nucleoside triphosphate hydrolases MHC antigen-recognition domain 11
NAD(P)-binding Rossmann-fold domains alpha/beta-Hydrolases 11
Supernatant protein factor (SPF), C-terminal domain Toll/Interleukin receptor TIR domain 11
Peptidase/esterase 'gauge' domain Quinoprotein alcohol dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases AN1-like Zinc finger 11
Galactose oxidase, central domain C-type lectin-like 11
GroES-like Mob1/phocein 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
Apolipoprotein A-I Apolipoprotein A-I 11
FabD/lysophospholipase-like alpha/beta-Hydrolases 11
CCHHC domain SAM/Pointed domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain Mitochondrial carrier 11
Glucocorticoid receptor-like (DNA-binding domain) WGR domain-like 11
N-terminal domain of MutM-like DNA repair proteins Ran binding protein zinc finger-like 11
TSP-1 type 1 repeat TIMP-like 11
Vacuolar ATP synthase subunit C Vacuolar ATP synthase subunit C 11
B-box zinc-binding domain B-box zinc-binding domain 11
SEA domain SRCR-like 11
Galactose-binding domain-like Galactose oxidase, central domain 11
Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain beta-beta-alpha zinc fingers 11
Nuclear receptor ligand-binding domain Nuclear receptor ligand-binding domain 11
Chaperone J-domain E set domains 11
Small-conductance potassium channel Small-conductance potassium channel 11
YccV-like ApaG-like 11
TPR-like Fic-like 11
P-loop containing nucleoside triphosphate hydrolases Immunoglobulin 11
Multidrug efflux transporter AcrB transmembrane domain WD40 repeat-like 11
KRAB domain (Kruppel-associated box) ENV polyprotein, receptor-binding domain 11
TNF receptor-like Growth factor receptor domain 11
VPS9 domain Ankyrin repeat 11
Myosin rod fragments FYVE/PHD zinc finger 11
RING/U-box Protein kinase-like (PK-like) 11
PH domain-like Tropomyosin 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Starch-binding domain-like PLC-like phosphodiesterases 11
Homeodomain-like Dimerisation domain of CENP-B 11
PH domain-like VPS9 domain 11
RCC1/BLIP-II Cytochrome b5-like heme/steroid binding domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
Mib/herc2 domain-like Tudor/PWWP/MBT 11
TIMP-like Concanavalin A-like lectins/glucanases 11
Ypt/Rab-GAP domain of gyp1p SH3-domain 11
E set domains Kazal-type serine protease inhibitors 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
Nucleotide-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
SAM/Pointed domain HD-domain/PDEase-like 11
Non-globular alpha+beta subunits of globular proteins ISP transmembrane anchor 11
S-adenosyl-L-methionine-dependent methyltransferases Metalloproteases ("zincins"), catalytic domain 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Ferritin-like SET domain 11
Growth factor receptor domain Leech antihemostatic proteins 11
Ubiquitin-like F-box domain 11
Retrovirus capsid dimerization domain-like Cysteine proteinases 11
PurS-like PurM C-terminal domain-like 11
P-loop containing nucleoside triphosphate hydrolases Cap-Gly domain 11
ARM repeat alpha/beta knot 11
WD40 repeat-like Hect, E3 ligase catalytic domain 11
Ribosomal protein L25-like C-terminal domain of ProRS 11
E set domains Cupredoxins 11
vWA-like GFP-like 11
CCCH zinc finger Protein kinase-like (PK-like) 11
Glucocorticoid receptor-like (DNA-binding domain) Lipocalins 11
Ankyrin repeat Ribosomal protein L32e 11
Myosin rod fragments Cysteine-rich domain 11
Metalloproteases ("zincins"), catalytic domain Growth factor receptor domain 11
GroES-like ACP-like 11
Protein kinase-like (PK-like) Myosin rod fragments 11
SMAD/FHA domain Cap-Gly domain 11
F-box domain Tricorn protease domain 2 11
Outer arm dynein light chain 1 PDZ domain-like 11
Ypt/Rab-GAP domain of gyp1p ACT-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase GroES-like 11
NAD(P)-binding Rossmann-fold domains ACP-like 11
ABC transporter transmembrane region MHC antigen-recognition domain 11
RING/U-box Formin homology 2 domain (FH2 domain) 11
DNA/RNA polymerases "Winged helix" DNA-binding domain 11
Growth factor receptor domain Methyl-accepting chemotaxis protein (MCP) signaling domain 11
NHL repeat WD40 repeat-like 11
Nop domain Nop domain 11
S-adenosyl-L-methionine-dependent methyltransferases GroES-like 11
F-box domain Cyclin-like 11
GroES-like alpha/beta-Hydrolases 11
RNI-like PDZ domain-like 11
RCC1/BLIP-II Concanavalin A-like lectins/glucanases 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
PH domain-like Cyclophilin-like 11
alpha-helical ferredoxin 4Fe-4S ferredoxins 11
Galactose-binding domain-like Kelch motif 11
Terpenoid cyclases/Protein prenyltransferases Kazal-type serine protease inhibitors 11
PLP-dependent transferases PK beta-barrel domain-like 11
ACP-like alpha/beta-Hydrolases 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Bet v1-like 11
Ribosomal protein L25-like Class II aaRS and biotin synthetases 11
ARM repeat FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 11
RCC1/BLIP-II Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Frizzled cysteine-rich domain Concanavalin A-like lectins/glucanases 11
Galactose oxidase, central domain Quinoprotein alcohol dehydrogenase-like 11
RCC1/BLIP-II Mib/herc2 domain-like 11
Somatomedin B domain Complement control module/SCR domain 11
FnI-like domain Leech antihemostatic proteins 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Nucleotidylyl transferase Class II aaRS and biotin synthetases 11
PAP/OAS1 substrate-binding domain Ubiquitin-like 11
EF-hand Galactose-binding domain-like 11
Chaperone J-domain Sec63 N-terminal domain-like 11
Galactose-binding domain-like Class II aaRS and biotin synthetases 11
Myosin rod fragments Regulator of G-protein signaling, RGS 11
Tricorn protease domain 2 DPP6 N-terminal domain-like 11
PH domain-like Formin homology 2 domain (FH2 domain) 11
RCC1/BLIP-II PH domain-like 11
Kringle-like SRCR-like 11
Thiolase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
BRCT domain Uteroglobin-like 11
FnI-like domain RNI-like 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
L9 N-domain-like Ribonuclease H-like 11
S-adenosyl-L-methionine-dependent methyltransferases alpha/beta-Hydrolases 11
Nucleotidylyl transferase C-terminal domain of ProRS 11
"Winged helix" DNA-binding domain SAICAR synthase-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase S-adenosyl-L-methionine-dependent methyltransferases 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
L domain-like Polo-box domain 11
Glucocorticoid receptor-like (DNA-binding domain) Domain of poly(ADP-ribose) polymerase 11
FabD/lysophospholipase-like ACP-like 11
Serine protease inhibitors Positive stranded ssRNA viruses 11
Nucleotide-binding domain 4Fe-4S ferredoxins 11
GroEL-intermediate domain like SAICAR synthase-like 11
V-type ATP synthase subunit C V-type ATP synthase subunit C 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Preprotein translocase SecY subunit Preprotein translocase SecY subunit 11
Ran binding protein zinc finger-like Cyclophilin-like 11
Quinoprotein alcohol dehydrogenase-like EF-hand 11
vWA-like Sensory domain-like 11
RING/U-box R3H domain 11
TIMP-like SEA domain 11
Serine protease inhibitors vWA-like 11
Soluble quinoprotein glucose dehydrogenase SRCR-like 11
Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain Formin homology 2 domain (FH2 domain) 11
UBA-like DNase I-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
Cysteine proteinases beta-beta-alpha zinc fingers 11
Actin depolymerizing proteins Toll/Interleukin receptor TIR domain 11
Calcium ATPase, transmembrane domain M Calcium ATPase, transmembrane domain M 11
Hook domain Hook domain 11
WD40 repeat-like dsRNA-binding domain-like 11
Methylated DNA-protein cysteine methyltransferase domain Methylated DNA-protein cysteine methyltransferase, C-terminal domain 11
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain WD40 repeat-like 11
Probable ACP-binding domain of malonyl-CoA ACP transacylase ACP-like 11
Calcyclin-binding protein-like HSP20-like chaperones 11
beta-beta-alpha zinc fingers Nucleic acid-binding proteins 11
Protein kinase-like (PK-like) BEACH domain 11
Ribosomal protein L32e Ribosomal protein L32e 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Second domain of FERM RING/U-box 11
GST C-terminal domain-like Class II aaRS ABD-related 11
Quinoprotein alcohol dehydrogenase-like Tricorn protease domain 2 11
RING/U-box Staphylococcal nuclease 11
Single hybrid motif Single hybrid motif 11
Concanavalin A-like lectins/glucanases Formin homology 2 domain (FH2 domain) 11
Cytochrome b5-like heme/steroid binding domain Galactose-binding domain-like 11
ARM repeat alpha/beta-Hydrolases 11
BRCT domain WGR domain-like 11
TPR-like Ran binding protein zinc finger-like 11
Ubiquitin-like AN1-like Zinc finger 11
Family A G protein-coupled receptor-like Immunoglobulin 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
DEATH domain Quinoprotein alcohol dehydrogenase-like 11
Putative DNA-binding domain PheT/TilS domain 11
PKD domain LDL receptor-like module 11
Quinoprotein alcohol dehydrogenase-like DPP6 N-terminal domain-like 11
Tricorn protease domain 2 ARM repeat 11
Leech antihemostatic proteins Leech antihemostatic proteins 11
EF-hand UBA-like 11
Myosin rod fragments G protein-binding domain 11
Fe-only hydrogenase Fe-only hydrogenase 11
Anthrax protective antigen Cupredoxins 11
GDNF receptor-like GDNF receptor-like 11
Spermadhesin, CUB domain Galactose oxidase, central domain 11
Tudor/PWWP/MBT Hect, E3 ligase catalytic domain 11
Galactose-binding domain-like TIMP-like 11
beta-sandwich domain of Sec23/24 ARM repeat 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
SMAD/FHA domain PX domain 11
PH domain-like HMG-box 11
SRCR-like POZ domain 11
BEACH domain FYVE/PHD zinc finger 11
Oligoxyloglucan reducing end-specific cellobiohydrolase Fibronectin type III 11
GST C-terminal domain-like Class II aaRS and biotin synthetases 11
Class II aaRS and biotin synthetases GAD domain-like 11
Flavoproteins Flavoproteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
ARID-like "Winged helix" DNA-binding domain 11
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 11
Myosin rod fragments PH domain-like 11
Doublecortin (DC) POZ domain 11
Nucleotide-diphospho-sugar transferases HAD-like 11
R3H domain AN1-like Zinc finger 11
Ankyrin repeat Heat shock protein 70kD (HSP70), C-terminal subdomain 11
PX domain CAD & PB1 domains 11
Ran binding protein zinc finger-like Cysteine proteinases 11
Oligoxyloglucan reducing end-specific cellobiohydrolase LDL receptor-like module 11
Thiolase-like ACP-like 11
S13-like H2TH domain Ran binding protein zinc finger-like 11
Galactose oxidase, central domain Fibronectin type III 11
TPR-like S-adenosyl-L-methionine-dependent methyltransferases 11
Calponin-homology domain, CH-domain Ubiquitin-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Smc hinge domain 11
(Phosphotyrosine protein) phosphatases II SMAD/FHA domain 11
S-adenosyl-L-methionine-dependent methyltransferases ACP-like 11
RNI-like Immunoglobulin 11
Acyl-CoA binding protein Supernatant protein factor (SPF), C-terminal domain 11
FYVE/PHD zinc finger EF-hand 11
KRAB domain (Kruppel-associated box) SET domain 11
Homeodomain-like Formin homology 2 domain (FH2 domain) 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
SIS domain SIS domain 11
(Phosphotyrosine protein) phosphatases II Nucleic acid-binding proteins 11
MIT domain Cysteine proteinases 11
Hemopexin-like domain Hemopexin-like domain 11
Eukaryotic type KH-domain (KH-domain type I) SAM/Pointed domain 11
FabD/lysophospholipase-like GroES-like 11
Mannose 6-phosphate receptor domain Kringle-like 11
EGF/Laminin Tropomyosin 11
Methionyl-tRNA synthetase (MetRS), Zn-domain S15/NS1 RNA-binding domain 11
Cytochrome b5-like heme/steroid binding domain Mib/herc2 domain-like 11
UBC-like Class II aaRS and biotin synthetases 11
SAM/Pointed domain Pseudo ankyrin repeat-like 11
alpha/beta-Hydrolases Bacterial exopeptidase dimerisation domain 11
Ankyrin repeat RNI-like 11
UBC-like Ribosomal protein S5 domain 2-like 11
Carboxypeptidase regulatory domain-like WD40 repeat-like 11
TSP-1 type 1 repeat GFP-like 11
Ribonuclease H-like "Winged helix" DNA-binding domain 11
Cytochrome b5-like heme/steroid binding domain HSP20-like chaperones 11
FYVE/PHD zinc finger SAICAR synthase-like 11
Oligoxyloglucan reducing end-specific cellobiohydrolase YWTD domain 11
Somatomedin B domain TSP-1 type 1 repeat 11
F-box domain Kelch motif 11
beta-beta-alpha zinc fingers WW domain 11
P-loop containing nucleoside triphosphate hydrolases Regulator of G-protein signaling, RGS 11
RAP domain-like RAP domain-like 11
Nucleotidylyl transferase Class II aaRS ABD-related 11
RUN domain-like PX domain 11
RNA-binding domain, RBD ClpP/crotonase 11
Thiolase-like S-adenosyl-L-methionine-dependent methyltransferases 11
KRAB domain (Kruppel-associated box) Nucleic acid-binding proteins 11
ARM repeat GYF domain 11
Thiolase-like FabD/lysophospholipase-like 11
ISP transmembrane anchor ISP domain 11
UDP-Glycosyltransferase/glycogen phosphorylase Cysteine proteinases 11
PurS-like Class I glutamine amidotransferase-like 11
Integrin alpha N-terminal domain WD40 repeat-like 11
Ribosomal protein L25-like Class II aaRS ABD-related 11
POZ domain Pentapeptide repeat-like 11
TPR-like RNI-like 11
L-aspartase-like CoA-transferase family III (CaiB/BaiF) 11
Thiolase-like alpha/beta-Hydrolases 11
GST C-terminal domain-like C-terminal domain of ProRS 11
Thioredoxin-like eEF1-gamma domain 11
RNI-like Actin depolymerizing proteins 11
Di-copper centre-containing domain Di-copper centre-containing domain 11
Concanavalin A-like lectins/glucanases Hect, E3 ligase catalytic domain 11
Acyl-CoA binding protein Ankyrin repeat 11
SAND domain-like HMG-box 11
Concanavalin A-like lectins/glucanases Trypsin-like serine proteases 11
Integrin alpha N-terminal domain EGF/Laminin 11
Proton glutamate symport protein Proton glutamate symport protein 11
Transthyretin (synonym: prealbumin) Transthyretin (synonym: prealbumin) 11
Concanavalin A-like lectins/glucanases FYVE/PHD zinc finger 11
Chromo domain-like Ankyrin repeat 11
Thiolase-like NAD(P)-binding Rossmann-fold domains 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
PH domain-like RBP11-like subunits of RNA polymerase 11
PDZ domain-like EF-hand 11
WD40 repeat-like Nucleoporin domain 11
N-terminal domain of cbl (N-cbl) UBA-like 11
L domain-like Putative isomerase YbhE 11
Galactose oxidase, central domain EGF/Laminin 11
B-box zinc-binding domain 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
Cytochrome b5-like heme/steroid binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Voltage-gated potassium channels EF-hand 11
beta-sandwich domain of Sec23/24 "Winged helix" DNA-binding domain 11
ARM repeat FYVE/PHD zinc finger 11
BRCT domain vWA-like 11
TRAF domain-like WD40 repeat-like 11
vWA-like FnI-like domain 11
Protein kinase-like (PK-like) HCP-like 11
Frizzled cysteine-rich domain C-type lectin-like 11
HLH, helix-loop-helix DNA-binding domain HMG-box 11
Ankyrin repeat Pseudo ankyrin repeat-like 11
Protein kinase-like (PK-like) Ras GEF 11
Cysteine-rich domain Multiheme cytochromes 11
Urocanase Urocanase 11
Non-globular alpha+beta subunits of globular proteins ISP domain 11
SMAD/FHA domain Bet v1-like 11
RCC1/BLIP-II VPS9 domain 11
Formin homology 2 domain (FH2 domain) Cysteine proteinases 11
HSP20-like chaperones Riboflavin synthase domain-like 11
SET domain WW domain 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Cytochrome b5-like heme/steroid binding domain Hect, E3 ligase catalytic domain 11
LDL receptor-like module Immunoglobulin 11
Lipovitellin-phosvitin complex, superhelical domain ARM repeat 11
Cadherin-like Family A G protein-coupled receptor-like 11
Nucleic acid-binding proteins GAD domain-like 11
Thioredoxin-like NHL repeat 11
HIT-like Immunoglobulin 11
S15/NS1 RNA-binding domain C-terminal domain of ProRS 11
HIT-like Fibronectin type III 11
Soluble quinoprotein glucose dehydrogenase Quinoprotein alcohol dehydrogenase-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Homocysteine S-methyltransferase Homocysteine S-methyltransferase 1