SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Domain combination pairs in Calditerrivibrio nitroreducens DSM 19672

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

577 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 3016
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 1710
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1511
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 139
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 1311
Homodimeric domain of signal transducing histidine kinase CheY-like 1210
Actin-like ATPase domain Actin-like ATPase domain 113
PYP-like sensor domain (PAS domain) CheY-like 108
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 102
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 104
CheY-like Homeodomain-like 91
CheY-like P-loop containing nucleoside triphosphate hydrolases 91
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 93
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 72
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 76
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 63
TPR-like TPR-like 66
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 65
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 54
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 53
Nucleotide cyclase EAL domain-like 55
PurM N-terminal domain-like PurM C-terminal domain-like 52
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 54
Triger factor/SurA peptide-binding domain-like FKBP-like 53
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 43
PYP-like sensor domain (PAS domain) Nucleotide cyclase 44
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 42
PreATP-grasp domain Rudiment single hybrid motif 43
Translation proteins EF-G C-terminal domain-like 42
Histidine-containing phosphotransfer domain, HPT domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 44
ACT-like ACT-like 42
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 44
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
Histidine-containing phosphotransfer domain, HPT domain CheY-like 44
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 44
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 44
lambda repressor-like DNA-binding domains RmlC-like cupins 41
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 42
PLP-binding barrel Alanine racemase C-terminal domain-like 42
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 42
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 43
Nucleic acid-binding proteins Nucleic acid-binding proteins 33
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 33
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 32
DNA methylase specificity domain DNA methylase specificity domain 33
CheY-like C-terminal effector domain of the bipartite response regulators 31
Thiolase-like Thiolase-like 31
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 31
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 33
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 31
"Winged helix" DNA-binding domain GAF domain-like 31
Periplasmic binding protein-like II PYP-like sensor domain (PAS domain) 33
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 31
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 33
Periplasmic binding protein-like II ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 31
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 32
Class II aaRS and biotin synthetases Class II aaRS ABD-related 33
RuvA domain 2-like Nucleic acid-binding proteins 33
Periplasmic binding protein-like II Homodimeric domain of signal transducing histidine kinase 33
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 33
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 32
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 33
CheY-like CheY-like 32
CheW-like CheY-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 31
Histidine-containing phosphotransfer domain, HPT domain Homodimeric domain of signal transducing histidine kinase 33
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 32
CheY-like Nucleotide cyclase 32
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 31
PYP-like sensor domain (PAS domain) EAL domain-like 33
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 21
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 22
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 21
Formyltransferase FMT C-terminal domain-like 21
TK C-terminal domain-like 4Fe-4S ferredoxins 22
CheC-like Surface presentation of antigens (SPOA) 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
GAF domain-like Nucleotide cyclase 22
CheY-like HD-domain/PDEase-like 22
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 21
GAF domain-like HD-domain/PDEase-like 22
GroES-like NAD(P)-binding Rossmann-fold domains 21
Periplasmic binding protein-like II CheY-like 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 21
HMA, heavy metal-associated domain HAD-like 22
PIN domain-like P-loop containing nucleoside triphosphate hydrolases 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III TK C-terminal domain-like 22
cAMP-binding domain-like CBS-domain pair 21
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 21
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 22
LeuD/IlvD-like Aconitase iron-sulfur domain 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 22
Calcium ATPase, transduction domain A HAD-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
WD40 repeat-like Caspase-like 22
HD-domain/PDEase-like Nucleotidyltransferase 22
DHH phosphoesterases CBS-domain pair 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 22
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 21
CheY-like GAF domain-like 22
PDZ domain-like PDZ domain-like 22
Histidine-containing phosphotransfer domain, HPT domain CheW-like 22
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 22
PUA domain-like Ribosomal protein S5 domain 2-like 22
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases TrpR-like 21
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 21
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Thiamin diphosphate-binding fold (THDP-binding) 22
Chaperone J-domain TPR-like 22
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 22
Calcium ATPase, transmembrane domain M HAD-like 22
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Nucleotidyltransferase Poly A polymerase C-terminal region-like 22
Thiamin diphosphate-binding fold (THDP-binding) 4Fe-4S ferredoxins 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
HD-domain/PDEase-like ACT-like 22
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 21
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
Nqo1 middle domain-like Nqo1C-terminal domain-like 22
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 21
Cytochrome c Cytochrome c 22
Multiheme cytochromes Multiheme cytochromes 21
HD-domain/PDEase-like HD-domain/PDEase-like 22
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 21
GAF domain-like Homodimeric domain of signal transducing histidine kinase 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 21
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
Thioredoxin-like Nqo1 middle domain-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Nucleotidyltransferase Nucleotidyltransferase substrate binding subunit/domain 22
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 22
Translation proteins Ribosomal protein S5 domain 2-like 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Actin-like ATPase domain HD-domain/PDEase-like 21
Thioredoxin-like Nqo1C-terminal domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheW-like 22
Nucleotidyltransferase ACT-like 22
PYP-like sensor domain (PAS domain) Histidine-containing phosphotransfer domain, HPT domain 22
Phase 1 flagellin Phase 1 flagellin 22
Thioredoxin-like Nqo1 FMN-binding domain-like 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 21
alpha-helical ferredoxin Nucleotide-binding domain 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Trypsin-like serine proteases PDZ domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 21
Quinoprotein alcohol dehydrogenase-like Caspase-like 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
Sensory domain-like HAMP domain-like 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
Aldolase Single hybrid motif 11
NagB/RpiA/CoA transferase-like alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
alpha-helical ferredoxin alpha-helical ferredoxin 11
Carbamate kinase-like ACT-like 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
Glutathione synthetase ATP-binding domain-like Single hybrid motif 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Acylphosphatase/BLUF domain-like YrdC/RibB 11
Clc chloride channel CBS-domain pair 11
Nucleic acid-binding proteins PheT/TilS domain 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like ClpP/crotonase 11
Fibronectin type III TPR-like 11
Aconitase B, N-terminal domain LeuD/IlvD-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
TGS-like Class II aaRS and biotin synthetases 11
HprK N-terminal domain-like PEP carboxykinase-like 11
DHH phosphoesterases Poly A polymerase C-terminal region-like 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
Lysozyme-like LysM domain 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
CBS-domain pair FAD-binding/transporter-associated domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Thioredoxin-like Six-hairpin glycosidases 11
Rudiment single hybrid motif post-HMGL domain-like 11
L,D-transpeptidase catalytic domain-like NTF2-like 11
Class II aaRS and biotin synthetases YbaK/ProRS associated domain 11
CBS-domain pair Nucleotidyltransferase 11
Translation proteins PRC-barrel domain 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
CheY-like Methylesterase CheB, C-terminal domain 11
Multidrug efflux transporter AcrB transmembrane domain cAMP-binding domain-like 11
ClpP/crotonase ClpP/crotonase 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
4Fe-4S ferredoxins FMN-linked oxidoreductases 11
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 11
PPK N-terminal domain-like PHP14-like 11
Galactose-binding domain-like Caspase-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, C-terminal domain 11
Cytochrome b5-like heme/steroid binding domain MFS general substrate transporter 11
CBS-domain pair Nucleotide cyclase 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Sensory domain-like Nucleotide cyclase 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
PYP-like sensor domain (PAS domain) GAF domain-like 11
Nucleotidyltransferase substrate binding subunit/domain Nucleotidyltransferase substrate binding subunit/domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
PreATP-grasp domain PreATP-grasp domain 11
FAD-binding/transporter-associated domain-like alpha-helical ferredoxin 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
6-phosphogluconate dehydrogenase C-terminal domain-like Nudix 11
Tex N-terminal region-like Nucleic acid-binding proteins 11
HAMP domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Nqo1 middle domain-like 4Fe-4S ferredoxins 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Homocysteine S-methyltransferase Methionine synthase domain 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
SP0561-like Periplasmic binding protein-like II 11
YVTN repeat-like/Quinoprotein amine dehydrogenase Caspase-like 11
NAD(P)-binding Rossmann-fold domains Nudix 11
Alpha subunit of glutamate synthase, C-terminal domain 4Fe-4S ferredoxins 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
Pectin lyase-like Concanavalin A-like lectins/glucanases 11
Transcription factor NusA, N-terminal domain Rad51 N-terminal domain-like 11
Nucleotidylyl transferase Riboflavin kinase-like 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 11
Sensory domain-like Homodimeric domain of signal transducing histidine kinase 11
Nqo1C-terminal domain-like alpha-helical ferredoxin 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Zinc beta-ribbon DNA primase core 11
Nqo1C-terminal domain-like Nucleotide-binding domain 11
Carbamate kinase-like PUA domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Tex N-terminal region-like RuvA domain 2-like 11
Alpha subunit of glutamate synthase, C-terminal domain Nucleotide-binding domain 11
Nucleotidyltransferase substrate binding subunit/domain HD-domain/PDEase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Voltage-gated potassium channels TrkA C-terminal domain-like 11
CBS-domain pair Poly A polymerase C-terminal region-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 11
Zinc beta-ribbon Zinc beta-ribbon 11
Translation proteins Translation proteins 11
RmlC-like cupins Isocitrate/Isopropylmalate dehydrogenase-like 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
WD40 repeat-like YVTN repeat-like/Quinoprotein amine dehydrogenase 11
Serine metabolism enzymes domain ACT-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
WD40 repeat-like MetI-like 11
4Fe-4S ferredoxins ADC-like 11
TGS-like ACT-like 11
HD-domain/PDEase-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
HprK N-terminal domain-like CBS-domain pair 11
FliG FliG 11
Nucleic acid-binding proteins Rad51 N-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
CbiG N-terminal domain-like CobE/GbiG C-terminal domain-like 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
Nucleic acid-binding proteins GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
PHP domain-like UDP-Glycosyltransferase/glycogen phosphorylase 11
DnaK suppressor protein DksA, alpha-hairpin domain Glucocorticoid receptor-like (DNA-binding domain) 11
PreATP-grasp domain Single hybrid motif 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
MetI-like MetI-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Thioredoxin-like 4Fe-4S ferredoxins 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
alpha-helical ferredoxin 4Fe-4S ferredoxins 11
GAF domain-like Homeodomain-like 11
NTF2-like NTF2-like 11
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 11
Tex N-terminal region-like Ribonuclease H-like 11
Rhodanese/Cell cycle control phosphatase P-loop containing nucleoside triphosphate hydrolases 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
PreATP-grasp domain Aldolase 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Sensory domain-like Methyl-accepting chemotaxis protein (MCP) signaling domain 11
Radical SAM enzymes RuvA domain 2-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
"Winged helix" DNA-binding domain LexA/Signal peptidase 11
YajQ-like YajQ-like 11
TPR-like Prim-pol domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
PheT/TilS domain Putative DNA-binding domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Hemerythrin-like 11
cAMP-binding domain-like "Winged helix" DNA-binding domain 11
Trimeric LpxA-like enzymes Phosphoglucomutase, first 3 domains 11
Nqo1 FMN-binding domain-like alpha-helical ferredoxin 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
PIN domain-like DNA/RNA polymerases 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
FAD-linked oxidases, C-terminal domain alpha-helical ferredoxin 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Prokaryotic type I DNA topoisomerase Zinc beta-ribbon 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 11
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains ClpP/crotonase 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
HlyD-like secretion proteins HlyD-like secretion proteins 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Macro domain-like Zn-dependent exopeptidases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
Ferritin-like Rubredoxin-like 11
GroEL equatorial domain-like GroEL apical domain-like 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain ACT-like 11
FAD/NAD-linked reductases, dimerisation (C-terminal) domain Rhodanese/Cell cycle control phosphatase 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
ClpP/crotonase NfeD domain-like 11
Glutathione synthetase ATP-binding domain-like Aldolase 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Aldolase AFP III-like domain 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
PreATP-grasp domain post-HMGL domain-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
FAD/NAD(P)-binding domain Rhodanese/Cell cycle control phosphatase 11
SpoIIaa-like ARM repeat 11
SirA-like DsrEFH-like 11
RuvA domain 2-like RuvA domain 2-like 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Ribonuclease H-like Nucleic acid-binding proteins 11
EspE N-terminal domain-like Chaperone J-domain 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
PreATP-grasp domain Methylglyoxal synthase-like 11
2Fe-2S ferredoxin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
Chorismate mutase II ACT-like 11
S-adenosyl-L-methionine-dependent methyltransferases DNA methylase specificity domain 11
Nucleotide-diphospho-sugar transferases RmlC-like cupins 11
2Fe-2S ferredoxin-like Riboflavin synthase domain-like 11
PHP14-like Phospholipase D/nuclease 11
RuvA domain 2-like BRCT domain 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
PK beta-barrel domain-like Molybdenum cofactor biosynthesis proteins 11
LysM domain LysM domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Translation proteins ThrRS/AlaRS common domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 11
TGS-like Class II aaRS ABD-related 11
Aminoacid dehydrogenase-like, N-terminal domain Isocitrate/Isopropylmalate dehydrogenase-like 11
DHH phosphoesterases Nucleotidyltransferase 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Alpha-L RNA-binding motif S-adenosyl-L-methionine-dependent methyltransferases 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
CheW-like Chemotaxis phosphatase CheZ 11
PDZ domain-like ClpP/crotonase 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Alpha subunit of glutamate synthase, C-terminal domain alpha-helical ferredoxin 11
CarD-like TRCF domain-like 11
CBS-domain pair ACT-like 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
GAF domain-like P-loop containing nucleoside triphosphate hydrolases 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 4Fe-4S ferredoxins 11
Nucleotide-binding domain 4Fe-4S ferredoxins 11
Prokaryotic type KH domain (KH-domain type II) Rad51 N-terminal domain-like 11
alpha/beta knot alpha/beta knot 11
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 11
Trimeric LpxA-like enzymes Phosphoglucomutase, C-terminal domain 11
Nucleic acid-binding proteins BRCT domain 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
GroEL-intermediate domain like GroEL apical domain-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
YjeF N-terminal domain-like Ribokinase-like 11
Rudiment single hybrid motif Single hybrid motif 11
P-loop containing nucleoside triphosphate hydrolases PilZ domain-like 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
Chemotaxis receptor methyltransferase CheR, N-terminal domain S-adenosyl-L-methionine-dependent methyltransferases 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Trigger factor ribosome-binding domain FKBP-like 11
Acylphosphatase/BLUF domain-like Actin-like ATPase domain 11
post-HMGL domain-like Single hybrid motif 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
Metallo-hydrolase/oxidoreductase Flavoproteins 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Bet v1-like NAD(P)-binding Rossmann-fold domains 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
DNA repair protein MutS, domain III SMR domain-like 11
YrdC/RibB RibA-like 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Barwin-like endoglucanases Sporulation related repeat 11
4Fe-4S ferredoxins 4Fe-4S ferredoxins 11
Aldolase post-HMGL domain-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
HD-domain/PDEase-like PYP-like sensor domain (PAS domain) 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
Sporulation related repeat Cysteine proteinases 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
Periplasmic binding protein-like II ACT-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
NosL/MerB-like NosL/MerB-like 11
HD-domain/PDEase-like TGS-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Nucleotidyltransferase Nucleotidyltransferase 11
Pectin lyase-like Pectin lyase-like 11
Eukaryotic type KH-domain (KH-domain type I) P-loop containing nucleoside triphosphate hydrolases 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
Class II aaRS and biotin synthetases GAD domain-like 11
Ribonuclease H-like RuvA domain 2-like 11
EspE N-terminal domain-like TPR-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
Nucleotidyltransferase substrate binding subunit/domain ACT-like 11
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 11
HIT-like HIT-like 11
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 11
HprK N-terminal domain-like DHH phosphoesterases 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Nqo1 FMN-binding domain-like 4Fe-4S ferredoxins 11
Nucleotidyltransferase TGS-like 11
Rudiment single hybrid motif Aldolase 11
Nucleotide-diphospho-sugar transferases Phosphoglucomutase, first 3 domains 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
EAL domain-like CBS-domain pair 11
2Fe-2S ferredoxin-like ADC-like 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
GAF domain-like PP2C-like 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
PK beta-barrel domain-like PK C-terminal domain-like 11
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Ribosomal protein L6 Ribosomal protein L6 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
TGS-like ThrRS/AlaRS common domain 11
EAL domain-like HD-domain/PDEase-like 11
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
Quinoprotein alcohol dehydrogenase-like WD40 repeat-like 11
PYP-like sensor domain (PAS domain) PP2C-like 11
all-alpha NTP pyrophosphatases all-alpha NTP pyrophosphatases 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
DNA clamp DNA clamp 11
NAD(P)-binding Rossmann-fold domains Isocitrate/Isopropylmalate dehydrogenase-like 11
Homodimeric domain of signal transducing histidine kinase CheW-like 11
Chorismate mutase II Periplasmic binding protein-like II 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
Nqo1C-terminal domain-like 4Fe-4S ferredoxins 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
Aconitase B, N-terminal domain Aconitase iron-sulfur domain 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
YrdC/RibB Actin-like ATPase domain 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
Cobalamin (vitamin B12)-binding domain Radical SAM enzymes 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
PUA domain-like alpha/beta knot 11
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 11
Lysozyme-like beta-lactamase/transpeptidase-like 11
PYP-like sensor domain (PAS domain) P-loop containing nucleoside triphosphate hydrolases 11
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
RNase III domain-like dsRNA-binding domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]