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Domain combination pairs in Paramecium tetraurelia

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

1043 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 37525
Growth factor receptor domain Growth factor receptor domain 285119
Voltage-gated potassium channels cAMP-binding domain-like 28510
Protein kinase-like (PK-like) EF-hand 23512
cAMP-binding domain-like cAMP-binding domain-like 22215
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 20149
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 19714
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 17310
Homodimeric domain of signal transducing histidine kinase CheY-like 1719
TPR-like TPR-like 16643
Homeodomain-like Homeodomain-like 16612
WD40 repeat-like WD40 repeat-like 11054
Calcium ATPase, transduction domain A HAD-like 1099
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 10810
Calcium ATPase, transmembrane domain M HAD-like 10711
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 946
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 924
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 924
RING/U-box RING/U-box 9019
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 8610
EF-hand EF-hand 7826
RNA-binding domain, RBD RNA-binding domain, RBD 7021
Pentapeptide repeat-like WD40 repeat-like 6744
Actin-like ATPase domain Actin-like ATPase domain 668
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 628
Voltage-gated potassium channels Voltage-gated potassium channels 568
SMAD/FHA domain RING/U-box 546
Cyclin-like Cyclin-like 495
Protein kinase-like (PK-like) PH domain-like 4810
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 4639
ABC transporter transmembrane region ABC transporter transmembrane region 454
Protein kinase-like (PK-like) Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 4510
CCCH zinc finger CCCH zinc finger 443
Thioredoxin-like Thioredoxin-like 4212
Nucleotide cyclase Nucleotide cyclase 4112
DUSP-like Cysteine proteinases 399
Thioredoxin-like GST C-terminal domain-like 396
ARM repeat ARM repeat 3813
cAMP-binding domain-like Protein kinase-like (PK-like) 375
P-loop containing nucleoside triphosphate hydrolases Translation proteins 3715
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 364
P-loop containing nucleoside triphosphate hydrolases WD40 repeat-like 3425
GroEL equatorial domain-like GroEL apical domain-like 334
GroEL equatorial domain-like GroEL-intermediate domain like 323
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 316
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 316
Ankyrin repeat Protein kinase-like (PK-like) 318
GroEL-intermediate domain like GroEL apical domain-like 312
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 309
CRAL/TRIO N-terminal domain CRAL/TRIO domain 305
SMAD/FHA domain SMAD/FHA domain 299
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 299
Pentapeptide repeat-like Quinoprotein alcohol dehydrogenase-like 2827
P-loop containing nucleoside triphosphate hydrolases Pentapeptide repeat-like 2622
Calcium ATPase, transduction domain A Nucleotide cyclase 266
TPR-like Protein prenylyltransferase 2619
Growth factor receptor domain Pectin lyase-like 249
PX domain PX domain 244
RING/U-box B-box zinc-binding domain 247
Protein kinase-like (PK-like) ARM repeat 2313
RING/U-box TRAF domain-like 239
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 2310
GroES-like NAD(P)-binding Rossmann-fold domains 233
L domain-like Ankyrin repeat 233
C2 domain (Calcium/lipid-binding domain, CaLB) vWA-like 213
Kelch motif Kelch motif 218
FYVE/PHD zinc finger FYVE/PHD zinc finger 206
(Phosphotyrosine protein) phosphatases II C2 domain (Calcium/lipid-binding domain, CaLB) 203
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 205
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 209
HIT/MYND zinc finger-like Protein kinase-like (PK-like) 202
PH domain-like BEACH domain 206
E set domains E set domains 2015
RNA-binding domain, RBD Retrovirus zinc finger-like domains 191
Translation proteins EF-G C-terminal domain-like 199
MIR domain MIR domain 196
Globin-like Globin-like 193
IP3 receptor type 1 binding core, domain 2 IP3 receptor type 1 binding core, domain 2 184
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 188
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 174
PH domain-like Cysteine proteinases 172
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 175
Ubiquitin-like Ubiquitin-like 1713
EF-G C-terminal domain-like EF-G C-terminal domain-like 177
DBL homology domain (DH-domain) PX domain 1710
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 178
PH domain-like Oxysterol-binding protein-like 177
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 175
BEACH domain WD40 repeat-like 176
PX domain WD40 repeat-like 163
EF-hand WD40 repeat-like 1613
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 164
HAD-like Nucleotide cyclase 166
RING/U-box RNI-like 165
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 164
SAM/Pointed domain SMAD/FHA domain 168
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 165
RNI-like RNI-like 1610
MIR domain IP3 receptor type 1 binding core, domain 2 155
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 155
Growth factor receptor domain gamma-Crystallin-like 151
B-box zinc-binding domain RNI-like 153
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 154
PH domain-like WD40 repeat-like 154
GAF domain-like GAF domain-like 151
PAZ domain Ribonuclease H-like 152
vWA-like Protein kinase-like (PK-like) 153
Chaperone J-domain HSP40/DnaJ peptide-binding domain 155
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 156
SET domain RuBisCo LSMT C-terminal, substrate-binding domain 155
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 156
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 144
P-loop containing nucleoside triphosphate hydrolases Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 143
"Winged helix" DNA-binding domain E2F-DP heterodimerization region 142
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 143
SNARE-like SNARE fusion complex 143
HCP-like TPR-like 1410
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 145
P-loop containing nucleoside triphosphate hydrolases Quinoprotein alcohol dehydrogenase-like 1413
Translation proteins Ribosomal protein S5 domain 2-like 146
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 145
Ankyrin repeat Ankyrin repeat 136
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 132
Polo-box domain Polo-box domain 134
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 138
Class II aaRS and biotin synthetases Class II aaRS ABD-related 136
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 133
(Trans)glycosidases Glycosyl hydrolase domain 134
Kelch motif POZ domain 136
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 135
HCP-like HCP-like 134
EF-hand Cysteine proteinases 1310
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 135
Protein prenylyltransferase Protein prenylyltransferase 1311
Galactose oxidase, central domain Kelch motif 137
Metalloproteases ("zincins"), catalytic domain ARM repeat 122
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 126
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 123
Leukotriene A4 hydrolase N-terminal domain ARM repeat 122
Cullin homology domain "Winged helix" DNA-binding domain 123
Nucleic acid-binding proteins Nucleic acid-binding proteins 124
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 122
Protein kinase-like (PK-like) Polo-box domain 123
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 125
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 125
Nucleic acid-binding proteins Translation proteins SH3-like domain 124
Domain of poly(ADP-ribose) polymerase ADP-ribosylation 125
Starch-binding domain-like (Phosphotyrosine protein) phosphatases II 113
WGR domain-like ADP-ribosylation 114
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 116
WGR domain-like Domain of poly(ADP-ribose) polymerase 114
(Trans)glycosidases E set domains 115
UBA-like Ubiquitin-like 116
Zn-finger domain of Sec23/24 vWA-like 117
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 1111
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Cysteine proteinases 112
P-loop containing nucleoside triphosphate hydrolases vWA-like 103
Cullin repeat-like Cullin homology domain 101
Tropomyosin Tropomyosin 105
Kelch motif Metallo-dependent phosphatases 101
Pectin lyase-like Pectin lyase-like 106
EF-hand PH domain-like 103
WD40 repeat-like RING/U-box 104
Ubiquitin-like ARM repeat 104
Cullin repeat-like "Winged helix" DNA-binding domain 101
FKBP-like TPR-like 103
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 103
RCC1/BLIP-II RCC1/BLIP-II 105
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 103
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 105
beta-sandwich domain of Sec23/24 Zn-finger domain of Sec23/24 106
Ubiquitin-like Cysteine proteinases 105
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 106
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 95
P-loop containing nucleoside triphosphate hydrolases HSP20-like chaperones 91
Voltage-gated potassium channels Nucleotide cyclase 91
Thiolase-like Thiolase-like 93
Ankyrin repeat PH domain-like 94
Starch-binding domain-like Starch-binding domain-like 93
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 91
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 96
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 91
Agglutinin HPA-like gamma-Crystallin-like 93
Ubiquitin-like Protein kinase-like (PK-like) 93
beta-sandwich domain of Sec23/24 vWA-like 95
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 91
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 92
t-snare proteins SNARE fusion complex 92
P-loop containing nucleoside triphosphate hydrolases RCC1/BLIP-II 94
TPR-like RING/U-box 92
SAM/Pointed domain RING/U-box 94
Ankyrin repeat Bromodomain 93
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 91
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 92
WD40 repeat-like Tricorn protease domain 2 96
vWA-like C-terminal, gelsolin-like domain of Sec23/24 84
EF-hand Quinoprotein alcohol dehydrogenase-like 87
P-loop containing nucleoside triphosphate hydrolases TGS-like 82
CAD & PB1 domains RING/U-box 83
PH domain-like Bet v1-like 85
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 82
GST C-terminal domain-like eEF1-gamma domain 83
Protein kinase-like (PK-like) RNI-like 86
Bet v1-like Oxysterol-binding protein-like 85
Cytochrome b5-like heme/steroid binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 83
Protein kinase-like (PK-like) WD40 repeat-like 86
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 83
EF-hand SAICAR synthase-like 81
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 84
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 81
SET domain SET domain 84
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 83
ARM repeat Clathrin adaptor appendage domain 84
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 84
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 84
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit P-loop containing nucleoside triphosphate hydrolases 83
Phospholipase D/nuclease Phospholipase D/nuclease 85
Nucleotide cyclase PH domain-like 84
B-box zinc-binding domain Kelch motif 84
CBS-domain pair CBS-domain pair 81
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 82
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 85
ARM repeat Formin homology 2 domain (FH2 domain) 82
Galactose mutarotase-like (Trans)glycosidases 71
P-loop containing nucleoside triphosphate hydrolases RING/U-box 72
Thioredoxin-like eEF1-gamma domain 72
Nucleotide cyclase Calcium ATPase, transmembrane domain M 73
Sec7 domain ARM repeat 74
Single hybrid motif CoA-dependent acyltransferases 73
FYVE/PHD zinc finger SET domain 74
P-loop containing nucleoside triphosphate hydrolases FYVE/PHD zinc finger 75
RNA-binding domain, RBD PABC (PABP) domain 75
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 74
L domain-like EF-hand 73
WD40 repeat-like TPR-like 74
P-loop containing nucleoside triphosphate hydrolases NAD(P)-binding Rossmann-fold domains 73
P-loop containing nucleoside triphosphate hydrolases Phosphoglycerate mutase-like 71
PEP carboxykinase N-terminal domain PEP carboxykinase-like 71
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 72
BAH domain FYVE/PHD zinc finger 71
Glycoside hydrolase/deacetylase Galactose mutarotase-like 72
TPR-like Protein kinase-like (PK-like) 74
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 72
Galactose mutarotase-like Glycosyl hydrolase domain 71
PX domain Protein kinase-like (PK-like) 72
P-loop containing nucleoside triphosphate hydrolases TPR-like 72
P-loop containing nucleoside triphosphate hydrolases PH domain-like 73
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 72
RING/U-box Cysteine proteinases 74
UBC-like Activating enzymes of the ubiquitin-like proteins 74
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 71
Ribonuclease H-like DNA/RNA polymerases 73
RNase III domain-like RNase III domain-like 64
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 63
E set domains P-loop containing nucleoside triphosphate hydrolases 65
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 64
Voltage-gated potassium channels EF-hand 62
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 64
ARM repeat WD40 repeat-like 64
UBA-like UBA-like 62
Guanido kinase N-terminal domain Glutamine synthetase/guanido kinase 62
UBC-like UBA-like 63
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain SAM/Pointed domain 62
RING/U-box Concanavalin A-like lectins/glucanases 62
Ankyrin repeat Domain of poly(ADP-ribose) polymerase 63
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 62
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 62
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 62
Pentapeptide repeat-like DPP6 N-terminal domain-like 66
HMG-box HMG-box 63
S-adenosyl-L-methionine-dependent methyltransferases RING/U-box 63
Flavoproteins Riboflavin synthase domain-like 62
C2 domain (Calcium/lipid-binding domain, CaLB) Protein kinase-like (PK-like) 62
Sec63 N-terminal domain-like E set domains 64
L domain-like L domain-like 65
Staphylococcal nuclease Staphylococcal nuclease 64
FYVE/PHD zinc finger Ypt/Rab-GAP domain of gyp1p 62
Metalloproteases ("zincins"), catalytic domain Growth factor receptor domain 62
Ankyrin repeat WGR domain-like 63
DPP6 N-terminal domain-like WD40 repeat-like 66
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 62
Protein kinase-like (PK-like) Kelch motif 62
C2 domain (Calcium/lipid-binding domain, CaLB) ARM repeat 62
Ankyrin repeat ADP-ribosylation 63
ADC-like P-loop containing nucleoside triphosphate hydrolases 62
BAR/IMD domain-like Ypt/Rab-GAP domain of gyp1p 61
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 65
DUSP-like Hect, E3 ligase catalytic domain 61
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 62
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 63
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 64
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 62
GroEL apical domain-like SAICAR synthase-like 62
EF-hand ARM repeat 64
Protein kinase-like (PK-like) KA1-like 62
Dipeptidyl peptidase I (cathepsin C), exclusion domain Cysteine proteinases 62
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 62
EF-hand PLC-like phosphodiesterases 63
Nucleotide cyclase P-loop containing nucleoside triphosphate hydrolases 62
ADC-like Cdc48 domain 2-like 62
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase NM domain-like 51
PH domain-like PX domain 54
Putative isomerase YbhE WD40 repeat-like 55
RNA-binding domain, RBD Eukaryotic type KH-domain (KH-domain type I) 54
Metallo-hydrolase/oxidoreductase cAMP-binding domain-like 53
SAM/Pointed domain Protein kinase-like (PK-like) 51
Ribosomal protein L6 Ribosomal protein L6 51
Quinoprotein alcohol dehydrogenase-like DPP6 N-terminal domain-like 55
E set domains Galactose-binding domain-like 55
ThrRS/AlaRS common domain Class II aaRS ABD-related 53
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 53
FYVE/PHD zinc finger SAICAR synthase-like 51
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 51
PK beta-barrel domain-like PK C-terminal domain-like 53
vWA-like SPOC domain-like 52
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 52
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 54
Ubiquitin-like C2 domain (Calcium/lipid-binding domain, CaLB) 51
FYVE/PHD zinc finger GroEL apical domain-like 51
Saposin Metallo-dependent phosphatases 52
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 52
Glutaminase/Asparaginase Ankyrin repeat 52
Starch-binding domain-like UDP-Glycosyltransferase/glycogen phosphorylase 52
Voltage-gated potassium channels HD-domain/PDEase-like 51
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase C-terminal domain-like 51
Cysteine proteinases Calpain large subunit, middle domain (domain III) 54
Kelch motif E set domains 54
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 52
Chromo domain-like FYVE/PHD zinc finger 54
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 53
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 53
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 51
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 52
P-loop containing nucleoside triphosphate hydrolases SMAD/FHA domain 53
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 52
EGF/Laminin RING/U-box 51
BRCT domain BRCT domain 53
PH domain-like PH domain-like 53
Translation proteins ThrRS/AlaRS common domain 53
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 51
Staphylococcal nuclease Tudor/PWWP/MBT 53
UBA-like Cysteine proteinases 53
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 43
ARM repeat Cysteine proteinases 42
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 42
"Winged helix" DNA-binding domain E set domains 43
YbaK/ProRS associated domain Class II aaRS and biotin synthetases 41
MIR domain EF-hand 42
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 41
RING/U-box Tudor/PWWP/MBT 42
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 43
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 43
TATA-box binding protein-like TATA-box binding protein-like 41
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 43
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 42
Ankyrin repeat Nucleotidyltransferase 42
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 41
Acyl-CoA N-acyltransferases (Nat) Bromodomain 41
TPR-like SET domain 42
YbaK/ProRS associated domain C-terminal domain of ProRS 41
E set domains Galactose oxidase, central domain 43
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 42
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 42
Translational machinery components L30e-like 42
GST C-terminal domain-like GST C-terminal domain-like 42
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 43
cAMP-binding domain-like Retrovirus zinc finger-like domains 41
YVTN repeat-like/Quinoprotein amine dehydrogenase WD40 repeat-like 44
P-loop containing nucleoside triphosphate hydrolases DPP6 N-terminal domain-like 44
Ubiquitin-like Ankyrin repeat 42
Quinoprotein alcohol dehydrogenase-like YVTN repeat-like/Quinoprotein amine dehydrogenase 44
ISP domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 42
PsbU/PolX domain-like Nucleotidyltransferase 42
Class II aaRS and biotin synthetases C-terminal domain of ProRS 41
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 43
Agglutinin HPA-like Agglutinin HPA-like 42
Ubiquitin-like EF-hand 42
Outer arm dynein light chain 1 L domain-like 43
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 41
YVTN repeat-like/Quinoprotein amine dehydrogenase Pentapeptide repeat-like 44
Class II aaRS ABD-related C-terminal domain of ProRS 41
Nqo1 middle domain-like Nqo1C-terminal domain-like 41
DNA clamp DNA clamp 41
Voltage-gated potassium channels Retrovirus zinc finger-like domains 41
Concanavalin A-like lectins/glucanases Growth factor receptor domain 44
DBL homology domain (DH-domain) PH domain-like 43
Cytochrome b5-like heme/steroid binding domain Cytochrome b5-like heme/steroid binding domain 41
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 42
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 41
Nucleoside diphosphate kinase, NDK Nucleoside diphosphate kinase, NDK 41
vWA-like Helical domain of Sec23/24 43
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 41
YbaK/ProRS associated domain Class II aaRS ABD-related 41
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases EF-hand 42
PR-1-like PR-1-like 42
GTPase activation domain, GAP VPS9 domain 41
Ankyrin repeat EF-hand 44
2Fe-2S ferredoxin-like alpha-helical ferredoxin 42
DNA polymerase beta, N-terminal domain-like PsbU/PolX domain-like 42
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 41
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 43
vWA-like UBC-like 42
Aconitase iron-sulfur domain LeuD/IlvD-like 41
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 41
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 41
RING/U-box FYVE/PHD zinc finger 41
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 41
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 43
TRAF domain-like TRAF domain-like 43
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 42
Ubiquitin-like Zn-binding ribosomal proteins 41
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 41
Nucleotidylyl transferase Ribosomal protein L25-like 43
Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 41
FYVE/PHD zinc finger Bromodomain 44
WD40 repeat-like Nucleoporin domain 44
PLP-binding barrel Alanine racemase C-terminal domain-like 43
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 41
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 42
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 42
NHL repeat WD40 repeat-like 44
ISP domain FAD/NAD(P)-binding domain 42
Ubiquitin-like vWA-like 32
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 32
Chromo domain-like Chromo domain-like 33
Heat shock protein 70kD (HSP70), C-terminal subdomain Heat shock protein 70kD (HSP70), C-terminal subdomain 31
AN1-like Zinc finger AN1-like Zinc finger 32
TPR-like HSP20-like chaperones 32
Ubiquitin-like Cap-Gly domain 32
HAD-like MFS general substrate transporter 32
PH domain-like CRAL/TRIO domain 31
Ypt/Rab-GAP domain of gyp1p EF-hand 33
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 32
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 31
UBA-like XPC-binding domain 31
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 32
CHY zinc finger-like RING/U-box 32
CHY zinc finger-like Zinc hairpin stack 32
Ypt/Rab-GAP domain of gyp1p Rhodanese/Cell cycle control phosphatase 33
Cyclophilin-like Carbohydrate phosphatase 31
EF-hand Calpain large subunit, middle domain (domain III) 33
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 33
Galactose oxidase, central domain POZ domain 31
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 31
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 33
Cystatin/monellin Cystatin/monellin 31
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 31
P-loop containing nucleoside triphosphate hydrolases RNase III domain-like 33
RING/U-box Cysteine-rich domain 32
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 31
Aminoacid dehydrogenase-like, N-terminal domain Aminoacid dehydrogenase-like, N-terminal domain 31
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 32
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 33
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 31
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 31
PH domain-like CRAL/TRIO N-terminal domain 31
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 32
E set domains Pectin lyase-like 33
NHL repeat Quinoprotein alcohol dehydrogenase-like 33
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 31
vWA-like C-terminal domain of Ku80 31
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 31
Class II aaRS and biotin synthetases Translation proteins 31
Cysteine proteinases Cysteine proteinases 32
Nucleotide cyclase MFS general substrate transporter 32
RING/U-box Chromo domain-like 33
TPR-like Chaperone J-domain 32
TPR-like RuBisCo LSMT C-terminal, substrate-binding domain 31
Chaperone J-domain Thioredoxin-like 31
Pentapeptide repeat-like Calcium-dependent phosphotriesterase 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
PUA domain-like Ribosomal protein S5 domain 2-like 31
CheY-like Protein kinase-like (PK-like) 31
RNA-binding domain, RBD RING/U-box 33
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 32
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 32
Quinoprotein alcohol dehydrogenase-like Nucleoporin domain 33
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
TPR-like vWA-like 32
PriA/YqbF domain GINS helical bundle-like 31
ACT-like Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 31
Alpha-L RNA-binding motif Pseudouridine synthase 31
Soluble quinoprotein glucose dehydrogenase Pentapeptide repeat-like 33
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 31
E set domains Glycosyl hydrolase domain 31
Actin depolymerizing proteins (Phosphotyrosine protein) phosphatases II 33
WWE domain WWE domain 32
CheY-like CheY-like 32
Macro domain-like Macro domain-like 33
Ubiquitin-like PH domain-like 31
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 32
Ubiquitin-like L domain-like 32
F-box domain RNI-like 32
Pseudouridine synthase PUA domain-like 31
NAD(P)-binding Rossmann-fold domains SCP-like 31
Zinc hairpin stack RING/U-box 32
Bromodomain P-loop containing nucleoside triphosphate hydrolases 33
B-box zinc-binding domain Concanavalin A-like lectins/glucanases 31
Protein kinase-like (PK-like) ENTH/VHS domain 31
Ubiquitin-like XPC-binding domain 31
Macro domain-like ADP-ribosylation 31
FYVE/PHD zinc finger Elongation factor TFIIS domain 2 32
TRAF domain-like Cysteine-rich domain 32
Ribonuclease H-like Ribonuclease H-like 33
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 31
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 33
Quinoprotein alcohol dehydrogenase-like Putative isomerase YbhE 33
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 32
Chromo domain-like Bromodomain 33
TolB, C-terminal domain WD40 repeat-like 33
B-box zinc-binding domain EF-hand 33
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 31
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 31
Soluble quinoprotein glucose dehydrogenase WD40 repeat-like 33
RING/U-box Homeodomain-like 32
PH domain-like (Phosphotyrosine protein) phosphatases II 31
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 32
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 31
RCC1/BLIP-II Protein kinase-like (PK-like) 31
SPOC domain-like C-terminal domain of Ku80 31
Galactose-binding domain-like ARM repeat 31
Kelch motif RING/U-box 33
PapD-like WD40 repeat-like 22
BRCT domain PsbU/PolX domain-like 21
RNA-binding domain, RBD Ran binding protein zinc finger-like 21
NAD(P)-binding Rossmann-fold domains Glycerol-3-phosphate (1)-acyltransferase 21
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 22
Cytochrome P450 HSP20-like chaperones 21
TPR-like ARM repeat 21
Ankyrin repeat TPR-like 21
Tropomyosin Protein kinase-like (PK-like) 22
Thiolase-like Substrate-binding domain of HMG-CoA reductase 22
Enolase N-terminal domain-like Enolase C-terminal domain-like 21
alpha/beta knot Nucleic acid-binding proteins 22
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 21
UBC-like Endosomal sorting complex assembly domain 21
P-loop containing nucleoside triphosphate hydrolases beta-beta-alpha zinc fingers 21
RNI-like Ubiquitin-like 21
Putative DNA-binding domain Putative DNA-binding domain 21
Ricin B-like lectins Ricin B-like lectins 22
ENTH/VHS domain GAT-like domain 21
TPR-like Cyclophilin-like 21
ADP-ribosylation WD40 repeat-like 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
Mannose-binding lectins PX domain 21
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit EF-hand 21
Putative DNA-binding domain PheT/TilS domain 21
Ribosomal L27 protein-like Nucleic acid-binding proteins 22
Ribonuclease H-like Retrovirus zinc finger-like domains 22
RNA-binding domain, RBD Surp module (SWAP domain) 22
Surp module (SWAP domain) Surp module (SWAP domain) 21
Formate/glycerate dehydrogenase catalytic domain-like DHS-like NAD/FAD-binding domain 21
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 21
WD40 repeat-like Calcium-dependent phosphotriesterase 22
SAM/Pointed domain P-loop containing nucleoside triphosphate hydrolases 21
HAD-like BRCT domain 21
POZ domain Skp1 dimerisation domain-like 21
HIT/MYND zinc finger-like Cysteine proteinases 21
DPP6 N-terminal domain-like DPP6 N-terminal domain-like 22
C2 domain (Calcium/lipid-binding domain, CaLB) alpha-D-mannose-specific plant lectins 21
Adenine nucleotide alpha hydrolases-like Adenine nucleotide alpha hydrolases-like 21
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 21
UBA-like Activating enzymes of the ubiquitin-like proteins 22
DBL homology domain (DH-domain) Second domain of FERM 21
TROVE domain-like vWA-like 22
Nucleic acid-binding proteins TPR-like 21
Thiolase-like NAD-binding domain of HMG-CoA reductase 22
RING/U-box BRCT domain 21
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 21
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 22
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 21
Acid proteases UBA-like 21
Ubiquitin-like UBC-like 21
Cap-Gly domain RNI-like 21
Pentapeptide repeat-like NHL repeat 22
Calponin-homology domain, CH-domain Calponin-homology domain, CH-domain 22
FKBP-like Cyclophilin-like 21
P-loop containing nucleoside triphosphate hydrolases Aldolase 22
Trypsin-like serine proteases PDZ domain-like 21
PX domain Ubiquitin-like 22
Rudiment single hybrid motif Single hybrid motif 21
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 22
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 21
Pentapeptide repeat-like TolB, C-terminal domain 22
SET domain P-loop containing nucleoside triphosphate hydrolases 21
Trypsin-like serine proteases Trypsin-like serine proteases 22
Elongation factor TFIIS domain 2 Zinc beta-ribbon 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 21
Sec7 domain PH domain-like 21
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
WW domain WW domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 21
Tetrapyrrole methylase Tetrapyrrole methylase 21
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 22
R3H domain Ribonuclease H-like 21
Putative DNA-binding domain Class II aaRS and biotin synthetases 21
Quinoprotein alcohol dehydrogenase-like Tricorn protease domain 2 22
Eukaryotic type KH-domain (KH-domain type I) RING/U-box 22
MFS general substrate transporter MFS general substrate transporter 21
DBL homology domain (DH-domain) Ubiquitin-like 22
Chaperone J-domain E set domains 21
ADP-ribosylation Pentapeptide repeat-like 22
E set domains Anthrax protective antigen 22
Ran binding protein zinc finger-like Ran binding protein zinc finger-like 22
Alkaline phosphatase-like Translation proteins SH3-like domain 21
Calcium ATPase, transmembrane domain M MFS general substrate transporter 21
PLP-dependent transferases PLP-dependent transferases 21
PX domain Second domain of FERM 21
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 21
Concanavalin A-like lectins/glucanases UBC-like 22
TPR-like "Winged helix" DNA-binding domain 21
WD40 repeat-like Cyclophilin-like 22
EPT/RTPC-like P-loop containing nucleoside triphosphate hydrolases 22
Growth factor receptor domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 21
PRP4-like Functional domain of the splicing factor Prp18 21
Chaperone J-domain Sec63 N-terminal domain-like 21
Single hybrid motif Single hybrid motif 21
HMG-box Chromo domain-like 21
Nucleotidylyl transferase Nucleotidylyl transferase 21
Family A G protein-coupled receptor-like SAICAR synthase-like 21
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 22
WD40 repeat-like S-adenosyl-L-methionine-dependent methyltransferases 22
Nucleic acid-binding proteins BRCT domain 22
vWA-like vWA-like 21
BRCT domain post-AAA+ oligomerization domain-like 21
Chaperone J-domain RNA-binding domain, RBD 21
ARM repeat P-loop containing nucleoside triphosphate hydrolases 22
Calponin-homology domain, CH-domain P-loop containing nucleoside triphosphate hydrolases 22
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 21
TPR-like Metallo-dependent phosphatases 21
Protein kinase-like (PK-like) Globin-like 21
YbiA-like RNA-binding domain, RBD 21
Sec7 domain Ypt/Rab-GAP domain of gyp1p 21
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 21
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 21
PH domain-like Phospholipase D/nuclease 22
Calcium ATPase, transduction domain A MFS general substrate transporter 21
Concanavalin A-like lectins/glucanases Activating enzymes of the ubiquitin-like proteins 22
YbiA-like SMAD/FHA domain 21
Protein kinase-like (PK-like) "Winged helix" DNA-binding domain 22
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 21
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 22
DNA primase core P-loop containing nucleoside triphosphate hydrolases 21
P-loop containing nucleoside triphosphate hydrolases Cytidine deaminase-like 21
EF-hand Chaperone J-domain 21
TPR-like PH domain-like 21
EPT/RTPC-like Aminoacid dehydrogenase-like, N-terminal domain 22
RNA-binding domain, RBD PWI domain 21
P-loop containing nucleoside triphosphate hydrolases RNA-binding domain, RBD 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Kelch motif P-loop containing nucleoside triphosphate hydrolases 22
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain WD40 repeat-like 21
PRTase-like PRTase-like 21
Pectin lyase-like Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 21
ClpP/crotonase ClpP/crotonase 21
Folate-binding domain Aminomethyltransferase beta-barrel domain 21
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 21
PheT/TilS domain Class II aaRS and biotin synthetases 21
Starch-binding domain-like HAD-like 21
ARM repeat Hect, E3 ligase catalytic domain 21
NAD(P)-binding Rossmann-fold domains DHS-like NAD/FAD-binding domain 21
Clavaminate synthase-like S-adenosyl-L-methionine-dependent methyltransferases 21
B-box zinc-binding domain TRAF domain-like 21
L domain-like HSP20-like chaperones 21
FF domain FF domain 22
RNI-like S-adenosyl-L-methionine-dependent methyltransferases 22
vWA-like Cysteine-rich domain 22
Nucleic acid-binding proteins eIF2alpha middle domain-like 21
UBA-like Ran binding protein zinc finger-like 22
C2 domain (Calcium/lipid-binding domain, CaLB) Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 21
Aldolase Aldolase 21
Translation proteins Initiation factor IF2/eIF5b, domain 3 22
Ubiquitin-like Chromo domain-like 21
Pre-PUA domain PUA domain-like 21
WD40 repeat-like Bromodomain 22
FYSH domain Hypothetical protein AF0491, middle domain 21
Concanavalin A-like lectins/glucanases UBA-like 22
DLC DLC 21
DUSP-like HIT/MYND zinc finger-like 21
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 21
Calpain large subunit, middle domain (domain III) Calpain large subunit, middle domain (domain III) 21
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 21
Aldolase NAD(P)-binding Rossmann-fold domains 22
RNI-like EF-hand 22
WD40 repeat-like RNI-like 22
Aldolase Aminoacid dehydrogenase-like, N-terminal domain 22
PreATP-grasp domain Single hybrid motif 21
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 21
ARM repeat Subdomain of clathrin and coatomer appendage domain 21
WW domain RNA-binding domain, RBD 21
Hypothetical protein c14orf129, hspc210 TPR-like 22
BRCT domain Nucleotidyltransferase 21
Nucleotidylyl transferase HD-domain/PDEase-like 21
E set domains Six-hairpin glycosidases 21
Actin depolymerizing proteins Actin depolymerizing proteins 22
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 21
Histone-fold ARM repeat 22
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) Protein kinase-like (PK-like) 22
P-loop containing nucleoside triphosphate hydrolases Tricorn protease domain 2 22
Clathrin heavy-chain terminal domain ARM repeat 21
Tricorn protease domain 2 TPR-like 21
Cytochrome P450 TPR-like 21
Eukaryotic type KH-domain (KH-domain type I) Retrovirus zinc finger-like domains 21
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain PX domain 21
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 22
P-loop containing nucleoside triphosphate hydrolases PX domain 21
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 21
PH domain-like Ypt/Rab-GAP domain of gyp1p 21
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 22
RING/U-box UBA-like 21
SMAD/FHA domain PP2C-like 21
Protein kinase-like (PK-like) SNARE-like 21
SMAD/FHA domain RNA-binding domain, RBD 21
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 21
EPT/RTPC-like Aldolase 22
EF-hand Putative isomerase YbhE 22
TolB, C-terminal domain Quinoprotein alcohol dehydrogenase-like 22
Doublecortin (DC) P-loop containing nucleoside triphosphate hydrolases 21
HMA, heavy metal-associated domain HAD-like 22
Galactose-binding domain-like Pectin lyase-like 22
RNI-like FabD/lysophospholipase-like 22
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 21
Outer arm dynein light chain 1 Protein kinase-like (PK-like) 21
Tropomyosin Myosin rod fragments 22
WW domain FF domain 22
Arginase/deacetylase SAICAR synthase-like 21
Ribonuclease H-like HRDC-like 21
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit Enolase C-terminal domain-like 21
BRCT domain P-loop containing nucleoside triphosphate hydrolases 21
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 21
Glutathione synthetase ATP-binding domain-like Single hybrid motif 21
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 21
WD40 repeat-like Ypt/Rab-GAP domain of gyp1p 21
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain alpha-D-mannose-specific plant lectins 21
Glycerol-3-phosphate (1)-acyltransferase Glycerol-3-phosphate (1)-acyltransferase 21
(Trans)glycosidases Six-hairpin glycosidases 21
PRP4-like WD40 repeat-like 22
ALDH-like ALDH-like 21
P-loop containing nucleoside triphosphate hydrolases Aminoacid dehydrogenase-like, N-terminal domain 22
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 22
Ubiquitin-like Acid proteases 21
EPT/RTPC-like NAD(P)-binding Rossmann-fold domains 22
PreATP-grasp domain Rudiment single hybrid motif 21
PapD-like Calponin-homology domain, CH-domain 21
BRCT domain DNA polymerase beta, N-terminal domain-like 21
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) HSC20 (HSCB), C-terminal oligomerisation domain 11
NHL repeat Nucleoporin domain 11
Dehydroquinate synthase-like P-loop containing nucleoside triphosphate hydrolases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HAD-like 11
UBA-like SMR domain-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Glutamine synthetase/guanido kinase Glutamine synthetase/guanido kinase 11
ARID-like ARM repeat 11
P-loop containing nucleoside triphosphate hydrolases Mannose 6-phosphate receptor domain 11
alpha/beta-Hydrolases Clavaminate synthase-like 11
Protein kinase-like (PK-like) Cyclin-like 11
HIT-like beta-carbonic anhydrase, cab 11
Nucleotide-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
mRNA decapping enzyme DcpS N-terminal domain HIT-like 11
Aquaporin-like PX domain 11
Anthrax protective antigen Galactose-binding domain-like 11
PUG domain-like Ubiquitin-like 11
ADP-ribosylation Quinoprotein alcohol dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
RNase III domain-like dsRNA-binding domain-like 11
Homeodomain-like Protein kinase-like (PK-like) 11
Outer arm dynein light chain 1 Ankyrin repeat 11
Pentapeptide repeat-like Nucleoporin domain 11
RING/U-box Fe-only hydrogenase 11
Multiheme cytochromes Pectin lyase-like 11
CCCH zinc finger WD40 repeat-like 11
GST C-terminal domain-like Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Mitochondrial carrier Thioredoxin-like 11
Ypt/Rab-GAP domain of gyp1p beta-sandwich domain of Sec23/24 11
Tex N-terminal region-like Retrovirus zinc finger-like domains 11
RING/U-box NAP-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
BAR/IMD domain-like (Phosphotyrosine protein) phosphatases II 11
Tropomyosin EF-hand 11
PX domain Phospholipase D/nuclease 11
Growth factor receptor domain Cytochrome b5-like heme/steroid binding domain 11
ARM repeat "Winged helix" DNA-binding domain 11
EF-hand TolB, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases YVTN repeat-like/Quinoprotein amine dehydrogenase 11
SNARE-like P-loop containing nucleoside triphosphate hydrolases 11
HAD-like P-loop containing nucleoside triphosphate hydrolases 11
Glucocorticoid receptor-like (DNA-binding domain) AN1-like Zinc finger 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
SNARE fusion complex SNARE fusion complex 11
Myosin rod fragments Myosin rod fragments 11
WD40 repeat-like Nitrous oxide reductase, N-terminal domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
DNA breaking-rejoining enzymes WD40 repeat-like 11
Outer arm dynein light chain 1 Outer arm dynein light chain 1 11
Thioredoxin-like Carboxypeptidase regulatory domain-like 11
Glutamine synthetase/guanido kinase beta-sandwich domain of Sec23/24 11
RING/U-box Cyclophilin-like 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
Mitochondrial carrier Mitochondrial carrier 11
Ribosomal protein L19 (L19e) Translational machinery components 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Growth factor receptor domain Agglutinin HPA-like 11
RING/U-box DHS-like NAD/FAD-binding domain 11
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 11
Dcp2 domain-like Nudix 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Putative isomerase YbhE Putative isomerase YbhE 11
L domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Macro domain-like Protein kinase-like (PK-like) 11
Protein kinase-like (PK-like) Ribonuclease H-like 11
cAMP-binding domain-like WD40 repeat-like 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
GST C-terminal domain-like Nucleotidylyl transferase 11
DNA polymerase beta, N-terminal domain-like Restriction endonuclease-like 11
Mitochondrial carrier GST C-terminal domain-like 11
Quinoprotein alcohol dehydrogenase-like Calcium-dependent phosphotriesterase 11
Translation proteins Translation proteins 11
Sm-like ribonucleoproteins SNARE fusion complex 11
RNA-binding domain, RBD ENTH/VHS domain 11
Growth factor receptor domain Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Surp module (SWAP domain) ENTH/VHS domain 11
EF-hand alpha/beta-Hydrolases 11
Ribonuclease H-like SH2 domain 11
L domain-like Protein kinase-like (PK-like) 11
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 11
B-box zinc-binding domain WD40 repeat-like 11
mRNA decapping enzyme DcpS N-terminal domain beta-carbonic anhydrase, cab 11
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 11
CheY-like HAD-like 11
ACP-like Oligoxyloglucan reducing end-specific cellobiohydrolase 11
Chaperone J-domain beta-beta-alpha zinc fingers 11
14-3-3 protein 14-3-3 protein 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
YVTN repeat-like/Quinoprotein amine dehydrogenase Tricorn protease domain 2 11
TPR-like Zn-binding ribosomal proteins 11
B-box zinc-binding domain FYVE/PHD zinc finger 11
Starch-binding domain-like DNase I-like 11
Concanavalin A-like lectins/glucanases Agglutinin HPA-like 11
Dehydroquinate synthase-like Aldolase 11
Zn-dependent exopeptidases Cysteine proteinases 11
Voltage-gated potassium channels WD40 repeat-like 11
Ubiquitin-like Tropomyosin 11
Tex N-terminal region-like Ribonuclease H-like 11
Cysteine proteinases Glutathione synthetase ATP-binding domain-like 11
Tricorn protease domain 2 Pectin lyase-like 11
gamma-Crystallin-like gamma-Crystallin-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Protein kinase-like (PK-like) Phospholipase C/P1 nuclease 11
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 11
E set domains AMPKBI-like 11
(Phosphotyrosine protein) phosphatases II P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Calcium-dependent phosphotriesterase 11
Carboxypeptidase regulatory domain-like WD40 repeat-like 11
ARM repeat RING/U-box 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
TPR-like RNA-binding domain, RBD 11
Formate/glycerate dehydrogenase catalytic domain-like Formate/glycerate dehydrogenase catalytic domain-like 11
PapD-like Rubredoxin-like 11
UDP-Glycosyltransferase/glycogen phosphorylase E set domains 11
Pentapeptide repeat-like 3-carboxy-cis,cis-mucoante lactonizing enzyme 11
Hook domain Protein kinase-like (PK-like) 11
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
RNI-like TPR-like 11
Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Ankyrin repeat Sec7 domain 11
(Phosphotyrosine protein) phosphatases II Mannose 6-phosphate receptor domain 11
Protein kinase-like (PK-like) Ypt/Rab-GAP domain of gyp1p 11
Dom34/Pelota N-terminal domain-like L30e-like 11
ARM repeat NSFL1 (p97 ATPase) cofactor p47, SEP domain 11
CCCH zinc finger RING/U-box 11
Galactose oxidase, central domain RING/U-box 11
Calponin-homology domain, CH-domain ARM repeat 11
Concanavalin A-like lectins/glucanases BEACH domain 11
UDP-Glycosyltransferase/glycogen phosphorylase PLP-binding barrel 11
Acyl-CoA binding protein Ankyrin repeat 11
PX domain RNI-like 11
CheY-like Rhodanese/Cell cycle control phosphatase 11
Growth factor receptor domain Multiheme cytochromes 11
Surp module (SWAP domain) Ribosomal protein S5 domain 2-like 11
Class II aaRS and biotin synthetases P-loop containing nucleoside triphosphate hydrolases 11
PYP-like sensor domain (PAS domain) CheY-like 11
beta-sandwich domain of Sec23/24 WD40 repeat-like 11
Dihydrofolate reductase-like Thymidylate synthase/dCMP hydroxymethylase 11
Retrovirus zinc finger-like domains ARM repeat 11
NAD-binding domain of HMG-CoA reductase Voltage-gated potassium channels 11
Ankyrin repeat C2 domain (Calcium/lipid-binding domain, CaLB) 11
PH domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
Class II aaRS and biotin synthetases SufE/NifU 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Putative isomerase YbhE YVTN repeat-like/Quinoprotein amine dehydrogenase 11
Mediator hinge subcomplex-like B-box zinc-binding domain 11
FMN-linked oxidoreductases 4Fe-4S ferredoxins 11
Anthrax protective antigen Pectin lyase-like 11
Calcium-dependent phosphotriesterase YVTN repeat-like/Quinoprotein amine dehydrogenase 11
beta-sandwich domain of Sec23/24 Nucleotide cyclase 11
PH domain-like Wiscott-Aldrich syndrome protein, WASP, C-terminal domain 11
Hedgehog/intein (Hint) domain ADP-ribosylation 11
E set domains Ankyrin repeat 11
Tropomyosin vWA-like 11
ARM repeat PH domain-like 11
PH domain-like PLC-like phosphodiesterases 11
Thiolase-like Voltage-gated potassium channels 11
beta-sandwich domain of Sec23/24 Glutathione synthetase ATP-binding domain-like 11
P-loop containing nucleoside triphosphate hydrolases NHL repeat 11
TPR-like Nucleotide-diphospho-sugar transferases 11
L30e-like alpha/beta knot 11
PurM N-terminal domain-like PurM C-terminal domain-like 11
WD40 repeat-like HIT/MYND zinc finger-like 11
HIT/MYND zinc finger-like TPR-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 11
Cysteine-rich domain Cysteine-rich domain 11
"Winged helix" DNA-binding domain RNA-binding domain, RBD 11
Concanavalin A-like lectins/glucanases WD40 repeat-like 11
RING/U-box Ubiquitin-like 11
Galactose-binding domain-like (Trans)glycosidases 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Ribosomal proteins L15p and L18e 11
CBD9-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Concanavalin A-like lectins/glucanases Ran binding protein zinc finger-like 11
UBA-like PUG domain-like 11
NagB/RpiA/CoA transferase-like LmbE-like 11
Cysteine-rich domain NAD kinase/diacylglycerol kinase-like 11
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment WD40 repeat-like 11
NAD-binding domain of HMG-CoA reductase cAMP-binding domain-like 11
Ubiquitin-like ADP-ribosylation 11
Nucleotide-binding domain FMN-linked oxidoreductases 11
YVTN repeat-like/Quinoprotein amine dehydrogenase DPP6 N-terminal domain-like 11
Tubby C-terminal domain-like Tubby C-terminal domain-like 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
vWA-like Cysteine proteinases 11
Homodimeric domain of signal transducing histidine kinase HAD-like 11
RNI-like Glutathione synthetase ATP-binding domain-like 11
Putative isomerase YbhE Calcium-dependent phosphotriesterase 11
PapD-like beta-sandwich domain of Sec23/24 11
Thioredoxin-like RING/U-box 11
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 11
Calcium-dependent phosphotriesterase Soluble quinoprotein glucose dehydrogenase 11
ARM repeat FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 11
Phosphofructokinase Phosphofructokinase 11
Pre-protein crosslinking domain of SecA TPR-like 11
3-carboxy-cis,cis-mucoante lactonizing enzyme WD40 repeat-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Alanine racemase C-terminal domain-like 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Chaperone J-domain 11
Ran binding protein zinc finger-like Cyclin-like 11
Ran binding protein zinc finger-like Activating enzymes of the ubiquitin-like proteins 11
Protein kinase-like (PK-like) Rhodanese/Cell cycle control phosphatase 11
Carbonic anhydrase Carbonic anhydrase 11
EF-hand DPP6 N-terminal domain-like 11
Protein kinase-like (PK-like) HSP40/DnaJ peptide-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Concanavalin A-like lectins/glucanases PH domain-like 11
Homodimeric domain of signal transducing histidine kinase Rhodanese/Cell cycle control phosphatase 11
RING/U-box DUSP-like 11
SH2 domain Retrovirus zinc finger-like domains 11
UBC-like Protein kinase-like (PK-like) 11
Protein kinase-like (PK-like) DnaJ/Hsp40 cysteine-rich domain 11
GST C-terminal domain-like Methionyl-tRNA synthetase (MetRS), Zn-domain 11
Galactose oxidase, central domain EGF/Laminin 11
Actin depolymerizing proteins C-terminal, gelsolin-like domain of Sec23/24 11
TPR-like cAMP-binding domain-like 11
Tudor/PWWP/MBT Elongation factor TFIIS domain 2 11
FMN-linked oxidoreductases FMN-linked oxidoreductases 11
Eukaryotic type KH-domain (KH-domain type I) DnaJ/Hsp40 cysteine-rich domain 11
Ran binding protein zinc finger-like UBC-like 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
EF-hand Mediator hinge subcomplex-like 11
Pentapeptide repeat-like Putative isomerase YbhE 11
UBC-like RNI-like 11
Ubiquitin-like Hedgehog/intein (Hint) domain 11
YVTN repeat-like/Quinoprotein amine dehydrogenase YVTN repeat-like/Quinoprotein amine dehydrogenase 11
alpha-helical ferredoxin 4Fe-4S ferredoxins 11
Mitochondrial carrier TPR-like 11
Methyl-accepting chemotaxis protein (MCP) signaling domain Tropomyosin 11
NAD(P)-binding Rossmann-fold domains CI-2 family of serine protease inhibitors 11
alpha-helical ferredoxin FMN-linked oxidoreductases 11
3-carboxy-cis,cis-mucoante lactonizing enzyme Quinoprotein alcohol dehydrogenase-like 11
ThrRS/AlaRS common domain P-loop containing nucleoside triphosphate hydrolases 11
RING/U-box PH domain-like 11
EF-hand DUSP-like 11
AlbA-like beta-sandwich domain of Sec23/24 11
RING/U-box ABC transporter transmembrane region 11
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 11
ENTH/VHS domain Ribosomal protein S5 domain 2-like 11
Metallo-dependent phosphatases PH domain-like 11
ARM repeat beta-sandwich domain of Sec23/24 11
P-loop containing nucleoside triphosphate hydrolases Soluble quinoprotein glucose dehydrogenase 11
ARM repeat alpha/beta knot 11
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain PH domain-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Multidrug resistance efflux transporter EmrE TPR-like 11
Eukaryotic type KH-domain (KH-domain type I) Chaperone J-domain 11
EF-hand NHL repeat 11
Acid proteases Acid proteases 11
Nucleotide-binding domain 4Fe-4S ferredoxins 11
Substrate-binding domain of HMG-CoA reductase cAMP-binding domain-like 11
FYVE/PHD zinc finger EF-hand 11
cAMP-binding domain-like Thiamin diphosphate-binding fold (THDP-binding) 11
Galactose oxidase, central domain Galactose oxidase, central domain 11
ADP-ribosylation B-box zinc-binding domain 11
Ribosomal L27 protein-like Eukaryotic type KH-domain (KH-domain type I) 11
Dehydroquinate synthase-like Aminoacid dehydrogenase-like, N-terminal domain 11
Protein kinase-like (PK-like) Cysteine proteinases 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Carbonic anhydrase SMAD/FHA domain 11
Guanido kinase N-terminal domain beta-sandwich domain of Sec23/24 11
CBD9-like Cytochrome b5-like heme/steroid binding domain 11
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 11
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 11
Pentapeptide repeat-like Tricorn protease domain 2 11
Insert subdomain of RNA polymerase alpha subunit 4Fe-4S ferredoxins 11
Thioredoxin-like WD40 repeat-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Protein kinase-like (PK-like) Chaperone J-domain 11
RING/U-box Oxysterol-binding protein-like 11
Hect, E3 ligase catalytic domain Hect, E3 ligase catalytic domain 11
HCP-like Zn-binding ribosomal proteins 11
Thiolase-like cAMP-binding domain-like 11
Dehydroquinate synthase-like NAD(P)-binding Rossmann-fold domains 11
RNA-binding domain, RBD Ribosomal protein S5 domain 2-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Chaperone J-domain 11
Dehydroquinate synthase-like EPT/RTPC-like 11
Dom34/Pelota N-terminal domain-like Translational machinery components 11
SNARE-like Domain of the SRP/SRP receptor G-proteins 11
(Trans)glycosidases UDP-Glycosyltransferase/glycogen phosphorylase 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
(Phosphotyrosine protein) phosphatases II C-terminal, gelsolin-like domain of Sec23/24 11
Nucleotide-binding domain FAD/NAD(P)-binding domain 11
Cyclophilin-like RNA-binding domain, RBD 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Rhodanese/Cell cycle control phosphatase 11
Substrate-binding domain of HMG-CoA reductase Voltage-gated potassium channels 11
N-terminal domain of adenylylcyclase associated protein, CAP C-terminal domain of adenylylcyclase associated protein 11
ATP-dependent DNA ligase DNA-binding domain BRCT domain 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
Sm-like ribonucleoproteins SNARE-like 11

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