Domain combination pairs in Medicago truncatula

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1737 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	L domain-like	873	131
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	470	94
L domain-like	L domain-like	469	109
L domain-like	Protein kinase-like (PK-like)	446	48
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	423	73
F-box domain	RNI-like	383	18
Toll/Interleukin receptor TIR domain	L domain-like	361	62
L domain-like	RNI-like	333	107
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	310	65
"Winged helix" DNA-binding domain	L domain-like	253	51
Toll/Interleukin receptor TIR domain	"Winged helix" DNA-binding domain	253	48
RNA-binding domain, RBD	RNA-binding domain, RBD	208	26
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	201	12
P-loop containing nucleoside triphosphate hydrolases	RNI-like	182	60
Actin-like ATPase domain	Actin-like ATPase domain	145	24
RNI-like	RNI-like	144	53
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	137	13
ABC transporter transmembrane region	ABC transporter transmembrane region	110	9
F-box domain	Galactose oxidase, central domain	105	5
Nucleic acid-binding proteins	Nucleic acid-binding proteins	102	25
RNI-like	Protein kinase-like (PK-like)	101	29
GroES-like	NAD(P)-binding Rossmann-fold domains	96	7
TPR-like	TPR-like	95	26
Thioredoxin-like	GST C-terminal domain-like	95	7
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	93	7
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	92	17
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	92	22
Calcium ATPase, transmembrane domain M	HAD-like	91	17
Calcium ATPase, transduction domain A	HAD-like	88	15
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	81	14
RING/U-box	ARM repeat	74	10
ARM repeat	ARM repeat	73	34
Thiolase-like	Thiolase-like	72	3
Cyclin-like	Cyclin-like	71	8
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	69	13
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	66	2
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	66	9
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	66	9
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	65	5
(Trans)glycosidases	Galactose-binding domain-like	63	12
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	63	2
RING/U-box	RING/U-box	58	20
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	57	7
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	56	9
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	56	6
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	54	6
Periplasmic binding protein-like I	Periplasmic binding protein-like II	54	5
Cupredoxins	Cupredoxins	54	5
POZ domain	Skp1 dimerisation domain-like	53	4
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	53	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	53	5
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	50	9
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	50	8
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	49	18
(Trans)glycosidases	Glycosyl hydrolase domain	48	11
Barwin-like endoglucanases	PHL pollen allergen	47	1
F-box domain	L domain-like	47	10
Homeodomain-like	Homeodomain-like	46	14
Voltage-gated potassium channels	cAMP-binding domain-like	46	5
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	45	9
CheY-like	Homeodomain-like	45	5
Protein kinase-like (PK-like)	EF-hand	44	2
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	43	11
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	42	6
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	42	6
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	41	8
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	41	5
CCCH zinc finger	CCCH zinc finger	40	17
Ubiquitin-like	Ubiquitin-like	40	10
DNA-binding domain	DNA-binding domain	39	5
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	39	5
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	38	2
RNA-binding domain, RBD	Ran binding protein zinc finger-like	38	3
F-box domain	Kelch motif	38	6
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	37	6
FYVE/PHD zinc finger	FYVE/PHD zinc finger	37	18
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	36	14
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	36	8
Galactose-binding domain-like	Galactose-binding domain-like	36	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	36	12
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	35	7
ACT-like	ACT-like	33	12
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	32	6
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	30	6
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	29	2
PUA domain-like	SET domain	29	3
ENTH/VHS domain	GAT-like domain	29	3
vWA-like	RING/U-box	28	4
DNA-binding pseudobarrel domain	CAD & PB1 domains	28	4
RING/U-box	Nucleotide-diphospho-sugar transferases	28	3
WRKY DNA-binding domain	WRKY DNA-binding domain	28	2
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	27	7
Cullin homology domain	"Winged helix" DNA-binding domain	27	4
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	27	3
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	27	4
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	26	7
ACT-like	Protein kinase-like (PK-like)	26	2
Surp module (SWAP domain)	Surp module (SWAP domain)	26	3
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	26	15
Phospholipase D/nuclease	Phospholipase D/nuclease	25	9
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	25	10
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	25	8
GroEL apical domain-like	GroEL equatorial domain-like	24	6
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	24	5
PAH2 domain	PAH2 domain	24	7
P-loop containing nucleoside triphosphate hydrolases	E set domains	24	4
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	24	6
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	23	4
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	23	4
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	23	4
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	23	4
Homeodomain-like	Bet v1-like	23	6
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	23	8
Clc chloride channel	CBS-domain pair	23	4
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	22	10
GroES-like	GroES-like	22	2
CBS-domain pair	CBS-domain pair	22	8
GroEL-intermediate domain like	GroEL apical domain-like	22	5
GroEL-intermediate domain like	GroEL equatorial domain-like	22	5
Ankyrin repeat	Ankyrin repeat	22	5
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	22	7
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	22	5
Thioredoxin-like	Thioredoxin-like	22	12
PAZ domain	Ribonuclease H-like	22	4
Ribonuclease H-like	DNA/RNA polymerases	22	4
EF-hand	Riboflavin synthase domain-like	22	2
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	22	5
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	21	5
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	21	6
Subtilisin-like	PA domain	21	4
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	21	9
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	21	8
FKBP-like	FKBP-like	21	8
Amine oxidase N-terminal region	Amine oxidase catalytic domain	21	3
E set domains	Ankyrin repeat	21	2
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	21	4
dsRNA-binding domain-like	dsRNA-binding domain-like	21	9
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	20	6
ARM repeat	Protein kinase-like (PK-like)	20	17
Homodimeric domain of signal transducing histidine kinase	CheY-like	20	6
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	20	3
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	20	7
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	20	1
Amine oxidase N-terminal region	Amine oxidase N-terminal region	20	3
Bet v1-like	Bet v1-like	20	6
SNARE-like	SNARE fusion complex	20	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	20	1
EF-G C-terminal domain-like	EF-G C-terminal domain-like	20	7
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	20	8
Translation proteins	EF-G C-terminal domain-like	20	7
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	20	8
Homeodomain-like	"Winged helix" DNA-binding domain	20	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	20	5
WD40 repeat-like	WD40 repeat-like	19	11
Cullin repeat-like	Cullin homology domain	19	4
Zinc hairpin stack	RING/U-box	19	5
FKBP-like	TPR-like	19	4
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	18	13
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	18	3
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	18	7
RING/U-box	Protein kinase-like (PK-like)	18	6
RING/U-box	FYVE/PHD zinc finger	18	9
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	18	3
Chromo domain-like	Chromo domain-like	18	3
TRAF domain-like	Ubiquitin-like	18	2
CHY zinc finger-like	RING/U-box	18	4
CHY zinc finger-like	Zinc hairpin stack	18	4
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	18	11
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	17	6
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	17	4
PK beta-barrel domain-like	PK C-terminal domain-like	17	2
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	17	1
EGF/Laminin	Protein kinase-like (PK-like)	17	5
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	17	11
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	17	5
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	17	5
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	17	2
ARM repeat	Hect, E3 ligase catalytic domain	17	4
F-box domain	Tubby C-terminal domain-like	17	3
Acid proteases	Saposin	17	1
FYVE/PHD zinc finger	SET domain	17	10
TATA-box binding protein-like	TATA-box binding protein-like	16	2
Starch-binding domain-like	Galactose-binding domain-like	16	3
TPR-like	HCP-like	16	12
YhbY-like	YhbY-like	16	6
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	16	4
Cullin repeat-like	"Winged helix" DNA-binding domain	16	2
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	16	5
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	16	9
FAS1 domain	FAS1 domain	16	3
Protein kinase-like (PK-like)	TPR-like	15	3
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	15	5
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	15	3
Galactose mutarotase-like	(Trans)glycosidases	15	3
Translation proteins	Ribosomal protein S5 domain 2-like	15	4
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	15	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	15	9
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	15	2
Protein kinase-like (PK-like)	WD40 repeat-like	15	4
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	15	2
Nucleic acid-binding proteins	Translation proteins SH3-like domain	15	4
EF-hand	EF-hand	15	7
Ankyrin repeat	RING/U-box	15	5
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	15	3
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	14	6
PA domain	Zn-dependent exopeptidases	14	3
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	14	10
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	14	6
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	14	3
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	14	7
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	14	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	14	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	14	3
HCP-like	HCP-like	14	7
NTF2-like	RNA-binding domain, RBD	14	2
Homeodomain-like	FAD-linked reductases, C-terminal domain	14	2
Galactose mutarotase-like	Glycosyl hydrolase domain	14	2
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	14	9
Homeodomain-like	FAD/NAD(P)-binding domain	14	2
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	14	4
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	14	10
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	14	7
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	13	2
RING/U-box	TRAF domain-like	13	3
E set domains	(Trans)glycosidases	13	6
Toll/Interleukin receptor TIR domain	RNI-like	13	9
ARM repeat	WD40 repeat-like	13	10
F-box domain	F-box domain	13	7
Protease propeptides/inhibitors	Subtilisin-like	13	3
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	13	5
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	13	2
(Trans)glycosidases	Ricin B-like lectins	13	3
Tropomyosin	Tropomyosin	13	4
Carbamate kinase-like	ACT-like	13	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	13	3
PGBD-like	Metalloproteases ("zincins"), catalytic domain	13	2
Ubiquitin-like	UBA-like	13	6
MFS general substrate transporter	MFS general substrate transporter	12	2
Protein kinase-like (PK-like)	Ankyrin repeat	12	3
Trypsin-like serine proteases	PDZ domain-like	12	5
ClpP/crotonase	ClpP/crotonase	12	5
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	12	7
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	12	4
HMA, heavy metal-associated domain	HAD-like	12	9
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	12	3
EF-hand	PLC-like phosphodiesterases	12	3
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	12	2
POZ domain	Ankyrin repeat	12	4
RNase III domain-like	dsRNA-binding domain-like	11	6
Class II aaRS and biotin synthetases	GAD domain-like	11	3
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	11	10
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	11	1
HAD-like	BRCT domain	11	3
BAR/IMD domain-like	SH3-domain	11	1
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	11	3
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	11	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	11	5
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	11	4
Flavoproteins	Riboflavin synthase domain-like	11	3
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	11	5
E set domains	Glycosyl hydrolase domain	11	5
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	11	5
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	11	4
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	11	1
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	11	4
C2 domain (Calcium/lipid-binding domain, CaLB)	EF-hand	11	2
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	11	1
Tudor/PWWP/MBT	FYVE/PHD zinc finger	10	5
Zn-finger domain of Sec23/24	vWA-like	10	4
WD40 repeat-like	RING/U-box	10	6
RING/U-box	Homeodomain-like	10	3
ARM repeat	Sec7 domain	10	5
Smc hinge domain	P-loop containing nucleoside triphosphate hydrolases	10	5
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	10	5
RCC1/BLIP-II	RCC1/BLIP-II	10	4
POZ domain	TRAF domain-like	10	2
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	10	4
BRCT domain	BRCT domain	10	8
beta-sandwich domain of Sec23/24	vWA-like	10	4
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	10	5
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	10	2
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	10	4
vWA-like	Helical domain of Sec23/24	10	4
Sec63 N-terminal domain-like	E set domains	10	4
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	10	4
Galactose-binding domain-like	Galactose mutarotase-like	10	3
t-snare proteins	SNARE fusion complex	10	3
PH domain-like	Oxysterol-binding protein-like	10	1
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	10	4
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	10	3
TPR-like	Chaperone J-domain	10	4
UBA-like	UBA-like	9	7
WW domain	WW domain	9	5
RmlC-like cupins	RmlC-like cupins	9	2
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	9	3
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	9	3
ARID-like	FYVE/PHD zinc finger	9	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	9	3
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	9	1
"Winged helix" DNA-binding domain	RNI-like	9	6
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	9	2
Homeodomain-like	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	9	2
Tudor/PWWP/MBT	SET domain	9	4
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	9	5
PreATP-grasp domain	Rudiment single hybrid motif	9	5
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	9	1
CCCH zinc finger	RNA-binding domain, RBD	9	4
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	3
Galactose mutarotase-like	Starch-binding domain-like	9	2
ISP domain	Bet v1-like	9	3
RING/U-box	Cysteine proteinases	9	5
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	9	4
RuBisCO, large subunit, small (N-terminal) domain	RuBisCo, C-terminal domain	9	2
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	9	5
Galactose oxidase, central domain	E set domains	9	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	9	4
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	9	7
E set domains	CBS-domain pair	9	2
RNase III domain-like	RNase III domain-like	9	6
ARM repeat	POZ domain	9	4
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	3
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	9	3
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	9	2
HD-domain/PDEase-like	Nucleotidyltransferase	9	6
Cysteine proteinases	UBA-like	9	3
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	9	5
CAD & PB1 domains	Protein kinase-like (PK-like)	8	1
EF-hand	Voltage-gated potassium channels	8	3
Nucleic acid-binding proteins	GAD domain-like	8	2
Initiation factor IF2/eIF5b, domain 3	Translation proteins	8	4
Adenine nucleotide alpha hydrolases-like	RING/U-box	8	1
Single hybrid motif	CoA-dependent acyltransferases	8	4
NAD(P)-binding Rossmann-fold domains	ACT-like	8	4
E set domains	AMPKBI-like	8	2
L domain-like	Formin homology 2 domain (FH2 domain)	8	2
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	8	4
Cysteine proteinases	Granulin repeat	8	2
Actin-crosslinking proteins	(Trans)glycosidases	8	1
DUSP-like	Cysteine proteinases	8	3
Nucleotidylyl transferase	Nucleotidylyl transferase	8	1
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	8	3
HIT/MYND zinc finger-like	Cysteine proteinases	8	1
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	8	4
Protein kinase-like (PK-like)	Formin homology 2 domain (FH2 domain)	8	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	8	1
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	8	4
FAD/NAD(P)-binding domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	8	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	8	3
DNA-binding pseudobarrel domain	P-loop containing nucleoside triphosphate hydrolases	8	6
ADC-like	Cdc48 domain 2-like	8	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	8	3
FAD-linked reductases, C-terminal domain	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	8	1
LysM domain	Protein kinase-like (PK-like)	8	2
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	8	3
POZ domain	POZ domain	8	6
Actin depolymerizing proteins	Actin depolymerizing proteins	8	4
(Trans)glycosidases	Chitinase insertion domain	8	4
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	8	2
Zinc beta-ribbon	Cyclin-like	8	2
CheY-like	CheY-like	8	1
PH domain-like	Bet v1-like	7	2
Nucleoside hydrolase	Nucleoside hydrolase	7	3
TAZ domain	FYVE/PHD zinc finger	7	3
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	7	3
Periplasmic binding protein-like II	ACT-like	7	1
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	7	4
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	7	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	7	2
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	7	5
RCC1/BLIP-II	FYVE/PHD zinc finger	7	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	7	3
PDZ domain-like	ClpP/crotonase	7	1
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	7	2
ENT-like	Tudor/PWWP/MBT	7	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	7	4
TPR-like	CAD & PB1 domains	7	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	7	2
RCC1/BLIP-II	Protein kinase-like (PK-like)	7	4
RNA-binding domain, RBD	PABC (PABP) domain	7	3
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	7	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	7	1
ARID-like	HMG-box	7	4
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	7	1
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	7	5
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	7	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	7	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	7	3
Surp module (SWAP domain)	Ubiquitin-like	7	1
DNase I-like	EF-hand	7	4
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	7	3
TRAF domain-like	Cysteine proteinases	7	2
L domain-like	Actin-like ATPase domain	7	6
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	7	1
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	7	2
"Winged helix" DNA-binding domain	E set domains	7	3
PH domain-like	FYVE/PHD zinc finger	7	2
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	7	4
Class II aaRS ABD-related	C-terminal domain of ProRS	7	2
"Winged helix" DNA-binding domain	Actin-like ATPase domain	7	6
P-loop containing nucleoside triphosphate hydrolases	Actin-like ATPase domain	7	6
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	7	3
TAZ domain	RING/U-box	7	3
Aconitase iron-sulfur domain	LeuD/IlvD-like	7	4
Carbamate kinase-like	ALDH-like	7	1
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	7	4
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	7	2
NAD(P)-binding Rossmann-fold domains	Galactose-binding domain-like	7	2
Voltage-gated potassium channels	TrkA C-terminal domain-like	7	1
RING/U-box	RNA-binding domain, RBD	7	1
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	7	2
POZ domain	TAZ domain	7	2
P-loop containing nucleoside triphosphate hydrolases	UBA-like	7	5
PurM N-terminal domain-like	PurM C-terminal domain-like	7	4
Enolase N-terminal domain-like	Enolase C-terminal domain-like	7	3
Ubiquitin-like	BAG domain	7	3
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	7	2
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	7	4
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	7	4
PAZ domain	RNase III domain-like	7	5
Thioredoxin-like	TPR-like	7	4
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	7	2
EF-hand	Mitochondrial carrier	7	2
F-box domain	HCP-like	7	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	7	3
Thioredoxin-like	Cysteine-rich domain	6	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	6	3
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	6	2
ACT-like	Formyltransferase	6	1
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	6	2
Voltage-gated potassium channels	Voltage-gated potassium channels	6	3
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	6	2
CBS-domain pair	CAD & PB1 domains	6	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	6	2
BAR/IMD domain-like	PH domain-like	6	4
SAP domain	FYVE/PHD zinc finger	6	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	6	4
PH domain-like	ArfGap/RecO-like zinc finger	6	4
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	6	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	6	2
Trypsin-like serine proteases	Trypsin-like serine proteases	6	5
GroEL apical domain-like	SAICAR synthase-like	6	3
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	6	1
Ubiquitin-like	Cap-Gly domain	6	2
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	6	3
Retrovirus zinc finger-like domains	RING/U-box	6	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	6	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	6	4
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	6	4
LEA14-like	LEA14-like	6	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	6	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	6	3
(Trans)glycosidases	(Trans)glycosidases	6	3
(Trans)glycosidases	Protein kinase-like (PK-like)	6	3
FAD/NAD(P)-binding domain	EF-hand	6	2
FYVE/PHD zinc finger	Plus3-like	6	3
Toll/Interleukin receptor TIR domain	Actin-like ATPase domain	6	5
Translational machinery components	L30e-like	6	3
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	6	4
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	6	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	6	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	6	2
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	6	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	6	3
Ribonuclease H-like	HRDC-like	6	2
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	6	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	6	1
GST C-terminal domain-like	eEF-1beta-like	6	3
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	6	2
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	6	1
PH domain-like	RCC1/BLIP-II	6	1
Plant lectins/antimicrobial peptides	Lysozyme-like	6	2
TPR-like	RING/U-box	6	3
Cysteine proteinases	Sec-C motif	6	1
POZ domain	TPR-like	6	4
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	6	1
RING/U-box	PUA domain-like	6	3
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	6	2
SWIB/MDM2 domain	Plus3-like	6	3
Ubiquitin-like	Zn-binding ribosomal proteins	6	1
Oxidoreductase molybdopterin-binding domain	E set domains	6	3
ARM repeat	Clathrin adaptor appendage domain	6	4
Ubiquitin-like	Protein kinase-like (PK-like)	6	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	6	4
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	6	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	6	2
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	6	2
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	6	1
PriA/YqbF domain	GINS helical bundle-like	6	2
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	6	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	6	1
Translation proteins	ThrRS/AlaRS common domain	6	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	6	2
FYVE/PHD zinc finger	Homeodomain-like	6	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	5	2
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	5	2
GST C-terminal domain-like	eEF1-gamma domain	5	1
TPR-like	"Winged helix" DNA-binding domain	5	2
ArfGap/RecO-like zinc finger	Ankyrin repeat	5	3
P-loop containing nucleoside triphosphate hydrolases	Epsilon subunit of F1F0-ATP synthase N-terminal domain	5	2
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	5	2
Voltage-gated potassium channels	Ankyrin repeat	5	1
Protein kinase-like (PK-like)	KA1-like	5	1
TRAF domain-like	TRAF domain-like	5	4
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	5	2
BEACH domain	WD40 repeat-like	5	4
cAMP-binding domain-like	Ankyrin repeat	5	1
SMAD/FHA domain	PP2C-like	5	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	5	3
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	5	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	5	1
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	5	3
HCP-like	HIT/MYND zinc finger-like	5	2
BAR/IMD domain-like	Ankyrin repeat	5	3
UBC-like	UBA-like	5	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	5	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	5	3
Thioredoxin-like	eEF1-gamma domain	5	1
F-box domain	Actin-like ATPase domain	5	1
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	1
Homeodomain-like	P-loop containing nucleoside triphosphate hydrolases	5	4
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	5	3
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	5	3
RING/U-box	UBA-like	5	2
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	5	4
Adenine nucleotide alpha hydrolases-like	YjgF-like	5	1
ARM repeat	Tudor/PWWP/MBT	5	4
PYP-like sensor domain (PAS domain)	GAF domain-like	5	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	5	4
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	5	2
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	5	1
GAF domain-like	CheY-like	5	3
PH domain-like	Ankyrin repeat	5	3
UROD/MetE-like	UROD/MetE-like	5	2
Class II aaRS and biotin synthetases	Translation proteins	5	1
GAF domain-like	GAF domain-like	5	1
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	5	5
FYVE/PHD zinc finger	SWIB/MDM2 domain	5	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	5	1
Ricin B-like lectins	Glycosyl hydrolase domain	5	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	5	2
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	5	3
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	1
Kelch motif	Kelch motif	5	3
SWIB/MDM2 domain	SWIB/MDM2 domain	5	2
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	5	3
SET domain	TPR-like	5	2
YjgF-like	YjgF-like	5	1
RBP11-like subunits of RNA polymerase	Insert subdomain of RNA polymerase alpha subunit	5	3
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	5	2
C-terminal domain of alpha and beta subunits of F1 ATP synthase	Epsilon subunit of F1F0-ATP synthase N-terminal domain	5	2
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	5	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	5	2
PLC-like phosphodiesterases	PLC-like phosphodiesterases	5	3
PAZ domain	dsRNA-binding domain-like	5	3
Chaperone J-domain	4Fe-4S ferredoxins	5	3
RNA-binding domain, RBD	PWI domain	5	2
Ribulose-phoshate binding barrel	Ribulose-phoshate binding barrel	5	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	5	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	5	2
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	5	3
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	5	3
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	5	2
CCCH zinc finger	RING/U-box	5	2
P-loop containing nucleoside triphosphate hydrolases	Tropomyosin	5	4
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	5	2
Ubiquitin-like	Homeodomain-like	5	1
Thioredoxin-like	"Winged helix" DNA-binding domain	4	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	4	3
Chaperone J-domain	CSL zinc finger	4	2
FYVE/PHD zinc finger	Clavaminate synthase-like	4	2
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	4	2
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	4	4
WD40 repeat-like	DNase I-like	4	2
Clathrin heavy-chain terminal domain	ARM repeat	4	1
E set domains	RNA-binding domain, RBD	4	1
SNARE fusion complex	SNARE fusion complex	4	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	4	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	4	2
ARM repeat	Subdomain of clathrin and coatomer appendage domain	4	3
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	4	2
Ubiquitin-like	Hect, E3 ligase catalytic domain	4	2
Hemopexin-like domain	Hemopexin-like domain	4	1
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	4	1
Arp2/3 complex subunits	Arp2/3 complex subunits	4	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	4	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	4	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	4	2
UBA-like	Hect, E3 ligase catalytic domain	4	2
Protein kinase-like (PK-like)	PP2C-like	4	4
P-loop containing nucleoside triphosphate hydrolases	F-box domain	4	4
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	4	2
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	4	2
P-loop containing nucleoside triphosphate hydrolases	TGS-like	4	2
tRNA-binding arm	Class II aaRS and biotin synthetases	4	2
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	3
F-box domain	HIT/MYND zinc finger-like	4	1
ARM repeat	TPR-like	4	3
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	4	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	4	2
SBT domain	Ankyrin repeat	4	2
PH domain-like	WD40 repeat-like	4	3
TPR-like	HSP20-like chaperones	4	2
USP8 N-terminal domain-like	JAB1/MPN domain	4	2
PH domain-like	Phospholipase D/nuclease	4	2
Putative DNA-binding domain	Putative DNA-binding domain	4	2
Putative isomerase YbhE	WD40 repeat-like	4	3
MIT domain	P-loop containing nucleoside triphosphate hydrolases	4	1
E set domains	E set domains	4	2
YrdC/RibB	RibA-like	4	2
Protein kinase-like (PK-like)	PH domain-like	4	2
vWA-like	Cysteine-rich domain	4	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	Epsilon subunit of F1F0-ATP synthase N-terminal domain	4	1
FYVE/PHD zinc finger	GYF domain	4	2
Chitinase insertion domain	Protein kinase-like (PK-like)	4	2
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	4	2
PRTase-like	PRTase-like	4	2
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	4	2
FYVE/PHD zinc finger	GroEL apical domain-like	4	2
BRCT domain	FYVE/PHD zinc finger	4	3
PH domain-like	BEACH domain	4	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	2
WW domain	FF domain	4	3
alpha-D-mannose-specific plant lectins	Hairpin loop containing domain-like	4	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	4	2
BRCT domain	RING/U-box	4	2
WW domain	P-loop containing nucleoside triphosphate hydrolases	4	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	4	3
FF domain	FF domain	4	3
Globin-like	Globin-like	4	1
CCCH zinc finger	HIT-like	4	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	4	2
PRTase-like	Ribulose-phoshate binding barrel	4	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	4	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	4	1
Hairpin loop containing domain-like	Protein kinase-like (PK-like)	4	2
Cyclophilin-like	TPR-like	4	1
PH domain-like	GTPase activation domain, GAP	4	1
ARID-like	Clavaminate synthase-like	4	2
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	4	1
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	4	3
Starch-binding domain-like	Phosphoglycerate mutase-like	4	1
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	4	3
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	4	2
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	4	3
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	4	4
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	4	2
ARM repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	4	4
PA domain	Transferrin receptor-like dimerisation domain	4	1
Kelch motif	Metallo-dependent phosphatases	4	2
PH domain-like	ARM repeat	4	3
FYVE/PHD zinc finger	Ankyrin repeat	4	1
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	4	1
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	4	3
FYVE/PHD zinc finger	Transducin (alpha subunit), insertion domain	4	2
Cysteine proteinases	Ubiquitin-like	4	2
Quinoprotein alcohol dehydrogenase-like	3-carboxy-cis,cis-mucoante lactonizing enzyme	4	3
ARM repeat	UBA-like	4	2
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	4	2
FYVE/PHD zinc finger	SAICAR synthase-like	4	2
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	4	2
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	4	1
WD40 repeat-like	F-box domain	4	3
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	4	1
PUG domain-like	Ubiquitin-like	4	3
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	3	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	3	3
Cytidine deaminase-like	Dihydrofolate reductase-like	3	2
Amidase signature (AS) enzymes	TPR-like	3	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	3	2
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	3	3
WGR domain-like	ADP-ribosylation	3	3
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	3	1
BRCA2 helical domain	BRCA2 tower domain	3	3
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	3	2
L domain-like	Elongation factor Ts (EF-Ts), dimerisation domain	3	3
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	3	1
E set domains	Cytochrome b5-like heme/steroid binding domain	3	2
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	3	2
DNase I-like	DNase I-like	3	2
PreATP-grasp domain	PreATP-grasp domain	3	3
Chaperone J-domain	Sec63 N-terminal domain-like	3	1
Cytochrome f, large domain	Rudiment single hybrid motif	3	2
Voltage-gated potassium channels	Glycosyl hydrolase domain	3	3
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	3	2
AN1-like Zinc finger	AN1-like Zinc finger	3	2
PapD-like	Ankyrin repeat	3	3
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	3	2
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	3	2
Cyclophilin-like	RNA-binding domain, RBD	3	1
Chaperone J-domain	E set domains	3	1
HAD-like	Thioredoxin-like	3	1
Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	3	1
beta and beta-prime subunits of DNA dependent RNA-polymerase	beta and beta-prime subunits of DNA dependent RNA-polymerase	3	2
"Winged helix" DNA-binding domain	Elongation factor Ts (EF-Ts), dimerisation domain	3	3
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	3	3
Translational machinery components	Insert subdomain of RNA polymerase alpha subunit	3	2
Tropomyosin	Apolipoprotein A-I	3	1
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
DNA-binding domain	DNA-binding pseudobarrel domain	3	3
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	3	2
Dom34/Pelota N-terminal domain-like	L30e-like	3	1
F-box domain	Protein kinase-like (PK-like)	3	2
HAD-like	Riboflavin kinase-like	3	1
Nucleic acid-binding proteins	eIF2alpha middle domain-like	3	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	3	1
Heme oxygenase-like	HAD-like	3	2
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	3	2
BRCT domain	DNA/RNA polymerases	3	1
RNA-binding domain, RBD	DNase I-like	3	2
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	3	2
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	3	1
Translational machinery components	RBP11-like subunits of RNA polymerase	3	2
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	3	1
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
SufE/NifU	BolA-like	3	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	3	2
HMA, heavy metal-associated domain	"Winged helix" DNA-binding domain	3	2
Cation efflux protein cytoplasmic domain-like	Cation efflux protein cytoplasmic domain-like	3	2
RNI-like	ARM repeat	3	1
Actin-crosslinking proteins	Actin-crosslinking proteins	3	1
HisI-like	all-alpha NTP pyrophosphatases	3	2
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	3	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	3	3
PurM C-terminal domain-like	PurM C-terminal domain-like	3	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	3	2
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	3	3
Dom34/Pelota N-terminal domain-like	Translational machinery components	3	1
E set domains	Riboflavin synthase domain-like	3	2
LysM domain	LysM domain	3	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	3	2
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	3	2
DEK C-terminal domain	ssDNA-binding transcriptional regulator domain	3	1
PurS-like	FGAM synthase PurL, linker domain	3	1
Phage tail proteins	Phage tail proteins	3	3
P-loop containing nucleoside triphosphate hydrolases	Elongation factor Ts (EF-Ts), dimerisation domain	3	3
Ribonuclease H-like	Ribonuclease H-like	3	2
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	3	1
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	3	1
PurM N-terminal domain-like	PurM N-terminal domain-like	3	1
PUA domain-like	Ribosomal protein S5 domain 2-like	3	2
Concanavalin A-like lectins/glucanases	BEACH domain	3	2
PurS-like	PurM C-terminal domain-like	3	1
PreATP-grasp domain	Single hybrid motif	3	3
Bacterial photosystem II reaction centre, L and M subunits	Photosystem II antenna protein-like	3	1
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	3	2
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	3	1
Thioredoxin-like	Ubiquitin-like	3	1
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	3	2
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	3	1
Ubiquitin-like	TPR-like	3	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	3	1
Saposin	Saposin	3	2
UBA-like	XPC-binding domain	3	2
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	3	1
Toll/Interleukin receptor TIR domain	UDP-Glycosyltransferase/glycogen phosphorylase	3	3
PurS-like	Class I glutamine amidotransferase-like	3	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	3	1
Scorpion toxin-like	Scorpion toxin-like	3	2
HLH, helix-loop-helix DNA-binding domain	ACT-like	3	2
Ribosomal protein L6	Ribosomal protein L6	3	1
Chaperone J-domain	RNA-binding domain, RBD	3	2
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	3	2
Osmotin, thaumatin-like protein	Protein kinase-like (PK-like)	3	2
Nucleotidylyl transferase	Ribosomal protein L25-like	3	2
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	3	2
Histone-fold	ARM repeat	3	2
PUA domain-like	alpha/beta knot	3	1
Class II aaRS and biotin synthetases	HD-domain/PDEase-like	3	3
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	3	2
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	2
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	3	1
Chaperone J-domain	Thioredoxin-like	3	2
Alpha-L RNA-binding motif	Pseudouridine synthase	3	1
Osmotin, thaumatin-like protein	alpha-D-mannose-specific plant lectins	3	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	3	2
GroEL-intermediate domain like	GroEL-intermediate domain like	3	2
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	3	3
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	3	3
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	3	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	3	2
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	3	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	3	1
Flavoproteins	Protein kinase-like (PK-like)	3	1
PheT/TilS domain	Class II aaRS and biotin synthetases	3	1
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	3	2
HAD-like	NHL repeat	3	1
Translation proteins	Translation proteins	3	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	3	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	3	2
WWE domain	ADP-ribosylation	3	2
PAH2 domain	F-box domain	3	1
Outer arm dynein light chain 1	L domain-like	3	3
PRP4-like	WD40 repeat-like	3	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	3	2
Tudor/PWWP/MBT	RNA-binding domain, RBD	3	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	3	3
Putative DNA-binding domain	PheT/TilS domain	3	1
PurS-like	PurM N-terminal domain-like	3	1
Rudiment single hybrid motif	Single hybrid motif	3	3
WD40 repeat-like	DPP6 N-terminal domain-like	3	2
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	3	2
Clavaminate synthase-like	Clavaminate synthase-like	3	1
HAD-like	NTF2-like	3	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	3	3
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	2
Ribosomal proteins S24e, L23 and L15e	Nucleic acid-binding proteins	3	2
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	3	2
P-loop containing nucleoside triphosphate hydrolases	UDP-Glycosyltransferase/glycogen phosphorylase	3	3
L domain-like	UDP-Glycosyltransferase/glycogen phosphorylase	3	3
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	3	2
Nucleic acid-binding proteins	BRCA2 tower domain	3	3
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	3	1
TPR-like	PUA domain-like	3	1
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	3	3
PH domain-like	HMG-box	3	1
Cullin repeat-like	Cullin repeat-like	3	3
Thioredoxin-like	NHL repeat	3	1
Concanavalin A-like lectins/glucanases	PH domain-like	3	2
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	3	2
POZ domain	RNI-like	3	2
DUSP-like	Ubiquitin-like	3	1
Macro domain-like	CRAL/TRIO domain	3	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	3	2
BRCA2 helical domain	Nucleic acid-binding proteins	3	3
Second domain of FERM	PH domain-like	3	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	3	2
Ubiquitin-like	XPC-binding domain	3	2
Cystatin/monellin	Cystatin/monellin	3	3
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	3	1
HIT-like	HIT-like	3	2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	3	2
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	2	1
Phage tail proteins	Phage fibre proteins	2	2
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	2	2
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	2	1
Heme-dependent peroxidases	Heme-dependent peroxidases	2	1
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	2	1
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Cytochrome f, large domain	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
SWIB/MDM2 domain	GYF domain	2	1
Barwin-like endoglucanases	Protein kinase-like (PK-like)	2	1
Clavaminate synthase-like	RING/U-box	2	2
Cytidine deaminase-like	YbiA-like	2	1
EF-hand	Calponin-homology domain, CH-domain	2	2
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	2	2
Urease, gamma-subunit	Urease, beta-subunit	2	2
Chelatase	Chlorophyll a-b binding protein	2	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	2	1
BSD domain-like	BSD domain-like	2	1
Cytochrome P450	Cytochrome P450	2	1
FAD/NAD(P)-binding domain	SMAD/FHA domain	2	1
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	2	1
F-box domain	SMI1/KNR4-like	2	2
WD40 repeat-like	SNARE fusion complex	2	2
Urease, gamma-subunit	Metallo-dependent hydrolases	2	2
FYVE/PHD zinc finger	TPR-like	2	1
Lipoxigenase	Class II aaRS and biotin synthetases	2	1
Tricorn protease domain 2	Quinoprotein alcohol dehydrogenase-like	2	2
Ubiquitin-like	L domain-like	2	2
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	2	1
HMA, heavy metal-associated domain	L domain-like	2	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	1
SAND domain-like	SET domain	2	1
BRCT domain	PsbU/PolX domain-like	2	1
L domain-like	Leucine zipper domain	2	1
SAP domain	RNA-binding domain, RBD	2	1
P-loop containing nucleoside triphosphate hydrolases	NAD(P)-binding Rossmann-fold domains	2	2
Clavaminate synthase-like	beta-beta-alpha zinc fingers	2	2
Tudor/PWWP/MBT	SAND domain-like	2	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	2	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	2	1
Phage tail proteins	gp5 N-terminal domain-like	2	2
Calcyclin-binding protein-like	HSP20-like chaperones	2	1
Macro domain-like	Zn-dependent exopeptidases	2	1
F-box domain	Acid proteases	2	1
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	2	2
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	2	2
Pentein	Pentein	2	1
HMA, heavy metal-associated domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Acetyl-CoA synthetase-like	ACP-like	2	2
beta-sandwich domain of Sec23/24	Leucine zipper domain	2	1
Ribosomal proteins S24e, L23 and L15e	YWTD domain	2	1
TPR-like	RNI-like	2	2
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
BRCT domain	Nucleotidyltransferase	2	1
Aldolase	NAD(P)-binding Rossmann-fold domains	2	1
PLP-dependent transferases	PLP-dependent transferases	2	2
CarD-like	TRCF domain-like	2	1
BRCT domain	post-AAA+ oligomerization domain-like	2	1
Urease, beta-subunit	Metallo-dependent hydrolases	2	2
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	2	1
Cullin repeat-like	POZ domain	2	1
Nucleic acid-binding proteins	S15/NS1 RNA-binding domain	2	1
(Phosphotyrosine protein) phosphatases II	E set domains	2	2
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	2
UBA-like	PUG domain-like	2	2
L domain-like	UBA-like	2	2
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	2	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	2	2
Pseudouridine synthase	Pseudouridine synthase	2	1
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	2	1
RING/U-box	Cyclophilin-like	2	1
Single hybrid motif	Single hybrid motif	2	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	2	1
ARID-like	HSP20-like chaperones	2	1
CAD & PB1 domains	RING/U-box	2	1
YVTN repeat-like/Quinoprotein amine dehydrogenase	WD40 repeat-like	2	2
Nucleic acid-binding proteins	BRCT domain	2	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	2	1
TPR-like	Metallo-dependent phosphatases	2	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	2	2
HydB/Nqo4-like	4Fe-4S ferredoxins	2	2
FAD/NAD(P)-binding domain	HI0933 insert domain-like	2	1
Smc hinge domain	Tropomyosin	2	1
F-box domain	alpha-D-mannose-specific plant lectins	2	1
Ran binding protein zinc finger-like	Translation proteins	2	1
Serine metabolism enzymes domain	ACT-like	2	2
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	2	1
Plus3-like	GYF domain	2	1
UraD-Like	Transthyretin (synonym: prealbumin)	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	2	1
TAZ domain	TAZ domain	2	1
Dcp2 domain-like	Nudix	2	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	2	1
P-loop containing nucleoside triphosphate hydrolases	alpha/beta-Hydrolases	2	2
Putative isomerase YbhE	Quinoprotein alcohol dehydrogenase-like	2	1
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	2	1
Ribonuclease H-like	RuvA domain 2-like	2	2
Nucleotidyltransferase	EF-hand	2	1
BRCT domain	ADP-ribosylation	2	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	2	1
Protein kinase-like (PK-like)	HSP20-like chaperones	2	2
L30e-like	alpha/beta knot	2	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	2	2
Enolase N-terminal domain-like	alpha/beta-Hydrolases	2	1
RING/U-box	Ran binding protein zinc finger-like	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
ARM repeat	SH3-domain	2	2
SWIB/MDM2 domain	CCCH zinc finger	2	1
F-box domain	Clavaminate synthase-like	2	2
RNA-binding domain, RBD	WW domain	2	1
F-box domain	NHL repeat	2	2
Formyltransferase	FMT C-terminal domain-like	2	1
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
cAMP-binding domain-like	ALDH-like	2	2
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	2	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	2	1
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	2	1
Plus3-like	CCCH zinc finger	2	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	2	1
Rudiment single hybrid motif	Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor	2	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Aspartate/glutamate racemase	Aspartate/glutamate racemase	2	1
Ribonuclease H-like	Nucleic acid-binding proteins	2	2
P-loop containing nucleoside triphosphate hydrolases	FAD/NAD(P)-binding domain	2	1
HAD-like	dsRNA-binding domain-like	2	2
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	2	2
Thioredoxin-like	Ypt/Rab-GAP domain of gyp1p	2	1
HD-domain/PDEase-like	TGS-like	2	2
Activator of Hsp90 ATPase, Aha1	Bet v1-like	2	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	2	1
PGBD-like	DnaJ/Hsp40 cysteine-rich domain	2	1
Periplasmic binding protein-like II	GlnB-like	2	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	2	2
YjeF N-terminal domain-like	FMN-binding split barrel	2	1
Surp module (SWAP domain)	ENTH/VHS domain	2	2
Insert subdomain of RNA polymerase alpha subunit	C-terminal domain of RNA polymerase alpha subunit	2	1
PX domain	BAR/IMD domain-like	2	2
ACP-like	Trimeric LpxA-like enzymes	2	2
Methylglyoxal synthase-like	Cytidine deaminase-like	2	1
cAMP-binding domain-like	cAMP-binding domain-like	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	2
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	2	1
FAD/NAD(P)-binding domain	ACP-like	2	2
Mannose-binding lectins	Mannose-binding lectins	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	1
Ribose/Galactose isomerase RpiB/AlsB	RmlC-like cupins	2	1
NTF2-like	Probable bacterial effector-binding domain	2	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	2	1
TRAF domain-like	Kix domain of CBP (creb binding protein)	2	1
PYP-like sensor domain (PAS domain)	F-box domain	2	2
PsbU/PolX domain-like	Nucleotidyltransferase	2	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	2	1
NAD(P)-binding Rossmann-fold domains	UDP-Glycosyltransferase/glycogen phosphorylase	2	2
L domain-like	Cysteine proteinases	2	2
GYF domain	SET domain	2	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	2	2
Dihydrofolate reductase-like	YbiA-like	2	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	1
vWA-like	SPOC domain-like	2	2
Nucleotidyltransferase	TGS-like	2	2
WD40 repeat-like	Bromodomain	2	1
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	2	1
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	2	1
Class I glutamine amidotransferase-like	ADC synthase	2	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
GST C-terminal domain-like	Ypt/Rab-GAP domain of gyp1p	2	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	2	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	2	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	2	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
PDZ domain-like	TPR-like	2	1
FYVE/PHD zinc finger	SAND domain-like	2	1
Photosystem I subunits PsaA/PsaB	Photosystem I subunits PsaA/PsaB	2	2
FYVE/PHD zinc finger	PUA domain-like	2	1
Ribosomal protein S2	Nucleotide-diphospho-sugar transferases	2	1
Outer arm dynein light chain 1	Protein kinase-like (PK-like)	2	2
Concanavalin A-like lectins/glucanases	HSP20-like chaperones	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	2	2
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	2	1
Translational machinery components	C-terminal domain of RNA polymerase alpha subunit	2	1
HMA, heavy metal-associated domain	Toll/Interleukin receptor TIR domain	2	1
Cullin repeat-like	Skp1 dimerisation domain-like	2	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	2	1
gp5 N-terminal domain-like	Phage fibre proteins	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	2	2
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	2	1
F-box domain	Leucine zipper domain	2	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	2
Six-hairpin glycosidases	AbfB domain	2	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	2	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
BRCT domain	WGR domain-like	2	2
Cysteine proteinases	Protein kinase-like (PK-like)	2	2
RNA-binding domain, RBD	Clavaminate synthase-like	2	1
"Winged helix" DNA-binding domain	F1F0 ATP synthase subunit A	2	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	2	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
Chaperone J-domain	Homeodomain-like	2	1
RBP11-like subunits of RNA polymerase	C-terminal domain of RNA polymerase alpha subunit	2	1
ADP-ribosylation	Hemopexin-like domain	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	2	2
Concanavalin A-like lectins/glucanases	RING/U-box	2	1
Cysteine-rich domain	Cysteine-rich domain	2	2
Translation proteins SH3-like domain	Ribosomal protein S19	2	1
Actin-like ATPase domain	AF1104-like	2	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	2	2
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	2	2
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	2	1
PDZ domain-like	PDZ domain-like	2	1
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	2	1
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	2	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	2	1
Thioredoxin-like	FAD-dependent thiol oxidase	2	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	2	1
Transmembrane di-heme cytochromes	a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)	2	1
SMAD/FHA domain	Phospholipase D/nuclease	2	2
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	2	1
GYF domain	CCCH zinc finger	2	1
HIT/MYND zinc finger-like	HIT/MYND zinc finger-like	2	1
RuvA domain 2-like	Nucleic acid-binding proteins	2	2
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	2	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Toll/Interleukin receptor TIR domain	UBA-like	2	2
Nucleotidylyl transferase	Nucleic acid-binding proteins	2	1
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	2	1
TPR-like	Ankyrin repeat	2	2
SAP domain	DNase I-like	2	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	2	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	2	2
Hypothetical protein c14orf129, hspc210	TPR-like	2	1
PUA domain-like	Nucleotidylyl transferase	2	1
Toll/Interleukin receptor TIR domain	Elongation factor Ts (EF-Ts), dimerisation domain	2	2
Riboflavin synthase domain-like	Riboflavin synthase domain-like	2	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	2	1
PP2C-like	cAMP-binding domain-like	2	2
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	2	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	2	1
Tricorn protease domain 2	WD40 repeat-like	2	2
CAD & PB1 domains	UBA-like	2	1
RuvA domain 2-like	RuvA domain 2-like	2	2
Acyl-CoA binding protein	Kelch motif	2	2
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	2	2
HD-domain/PDEase-like	EF-hand	2	1
Rhomboid-like	UBA-like	2	1
PH domain-like	BSD domain-like	2	1
Retrovirus zinc finger-like domains	RNA-binding domain, RBD	2	2
Tex N-terminal region-like	Ribonuclease H-like	2	2
FYVE/PHD zinc finger	CCCH zinc finger	2	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	2	1
HMG-box	HMG-box	2	2
Tubulin nucleotide-binding domain-like	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	2	1
HCP-like	Homing endonucleases	2	1
HIT/MYND zinc finger-like	RING/U-box	2	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	2	1
UBC-like	RING/U-box	2	2
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	2	2
GroEL equatorial domain-like	DNA-binding domain	2	1
Cytidine deaminase-like	Cytidine deaminase-like	2	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
ARM repeat	alpha/beta-Hydrolases	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	2	2
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	2	2
Histone-fold	NAP-like	2	1
PH domain-like	Prismane protein-like	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
TGS-like	ACT-like	1	1
Carbohydrate phosphatase	HAD-like	1	1
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	1	1
HMA, heavy metal-associated domain	NosL/MerB-like	1	1
PYP-like sensor domain (PAS domain)	Kelch motif	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	1	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	1	1
P-loop containing nucleoside triphosphate hydrolases	Cytochrome c oxidase subunit II-like, transmembrane region	1	1
TGS-like	Class II aaRS ABD-related	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
Fe-S cluster assembly (FSCA) domain-like	FKBP-like	1	1
Toll/Interleukin receptor TIR domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Helical scaffold and wing domains of SecA	Helical scaffold and wing domains of SecA	1	1
Ubiquitin-like	Bromodomain	1	1
ARM repeat	Clavaminate synthase-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
Pectin lyase-like	Pectin lyase-like	1	1
Nucleotide-binding domain	Nucleotide-binding domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
Phosphoglucomutase, C-terminal domain	Phosphoglucomutase, C-terminal domain	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Aldolase	Ribulose-phoshate binding barrel	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
dsRNA-binding domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
"Winged helix" DNA-binding domain	DNA-binding pseudobarrel domain	1	1
WD40 repeat-like	Peptidase/esterase 'gauge' domain	1	1
RNA-binding domain, RBD	N-terminal domain of alpha and beta subunits of F1 ATP synthase	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
L domain-like	DNA-binding pseudobarrel domain	1	1
TAF(II)230 TBP-binding fragment	Bromodomain	1	1
SSo0622-like	Kelch motif	1	1
Cyclin-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Nucleic acid-binding proteins	Ribosomal protein S7	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
Typo IV secretion system protein TraC	NTF2-like	1	1
Cna protein B-type domain	Carboxypeptidase regulatory domain-like	1	1
ALDH-like	ALDH-like	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
Aquaporin-like	HMA, heavy metal-associated domain	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	PLP-dependent transferases	1	1
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	1	1
Metallo-dependent hydrolases	Metallo-dependent hydrolases	1	1
L domain-like	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
POZ domain	Galactose-binding domain-like	1	1
"Winged helix" DNA-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Carbohydrate phosphatase	1	1
S15/NS1 RNA-binding domain	HydB/Nqo4-like	1	1
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
YggU-like	Glutathione synthetase ATP-binding domain-like	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Cytochrome b559 subunits	Photosystem II reaction center protein L, PsbL	1	1
FAD/NAD(P)-binding domain	DNA-binding domain	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
Cytochrome P450	Calcium-dependent phosphotriesterase	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	1	1
RNI-like	SGNH hydrolase	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
YgbK-like	Aldolase	1	1
CBS-domain pair	DNA-binding pseudobarrel domain	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
Nucleotidyltransferase	ACT-like	1	1
Phage fibre proteins	Phage fibre proteins	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
POZ domain	Pentapeptide repeat-like	1	1
Ribonuclease Rh-like	Protein kinase-like (PK-like)	1	1
vWA-like	C-terminal domain of Ku80	1	1
Sec1/munc18-like (SM) proteins	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	PR-1-like	1	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	1	1
F-box domain	Glutathione synthetase ATP-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	UBC-like	1	1
gp5 N-terminal domain-like	Ankyrin repeat	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	alpha/beta-Hydrolases	1	1
WD40 repeat-like	Galactose oxidase, central domain	1	1
RING/U-box	Leucine zipper domain	1	1
NAD(P)-binding Rossmann-fold domains	F-box domain	1	1
Pseudouridine synthase	PUA domain-like	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
DNA clamp	DNA clamp	1	1
Dimeric alpha+beta barrel	Dehydroquinate synthase-like	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Toll/Interleukin receptor TIR domain	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
Band 7/SPFH domain	DNA/RNA polymerases	1	1
Homeodomain-like	L domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Cupredoxins	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
CBS-domain pair	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
FYVE/PHD zinc finger	RNI-like	1	1
Nucleic acid-binding proteins	RNA-binding domain, RBD	1	1
Ribosomal protein S2	S-adenosyl-L-methionine-dependent methyltransferases	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	GHMP Kinase, C-terminal domain	1	1
Lipoxigenase	Metal cation-transporting ATPase, ATP-binding domain N	1	1
CoA-dependent acyltransferases	CoA-dependent acyltransferases	1	1
Phage tail proteins	Tricorn protease N-terminal domain	1	1
Thioredoxin-like	VC0467-like	1	1
HMA, heavy metal-associated domain	FAD/NAD(P)-binding domain	1	1
Ribosomal protein S8	RuBisCo, C-terminal domain	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
SAP domain	CCCH zinc finger	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	Cytochrome c oxidase subunit II-like, transmembrane region	1	1
CCCH zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Metallo-hydrolase/oxidoreductase	Casein kinase II beta subunit	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
Ada DNA repair protein, N-terminal domain (N-Ada 10)	TATA-box binding protein-like	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
Nucleotide-diphospho-sugar transferases	RmlC-like cupins	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	1	1
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Ribosomal protein S5 domain 2-like	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
PH domain-like	"Winged helix" DNA-binding domain	1	1
Serpins	P-loop containing nucleoside triphosphate hydrolases	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	Phosphoglycerate kinase	1	1
FKBP-like	Rhodanese/Cell cycle control phosphatase	1	1
RuvA domain 2-like	SH2 domain	1	1
Outer arm dynein light chain 1	RNI-like	1	1
SAP domain	ADP-ribosylation	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
SufE/NifU	NadA-like	1	1
Class II aaRS and biotin synthetases	Class II aaRS and biotin synthetases	1	1
SNARE-like	SNARE-like	1	1
Periplasmic binding protein-like I	Periplasmic binding protein-like I	1	1
ARM repeat	Chaperone J-domain	1	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
ARM repeat	alpha/beta knot	1	1
Ankyrin repeat	Translation initiation factor IF3, N-terminal domain	1	1
AN1-like Zinc finger	beta-beta-alpha zinc fingers	1	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	1	1
Peptidase/esterase 'gauge' domain	SNARE fusion complex	1	1
Starch-binding domain-like	Nucleic acid-binding proteins	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	Clavaminate synthase-like	1	1
F-box domain	NTF2-like	1	1
CCCH zinc finger	WD40 repeat-like	1	1
P-loop containing nucleoside triphosphate hydrolases	GIY-YIG endonuclease	1	1
ClpP/crotonase	Thiolase-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	1	1
Homeodomain-like	Tetracyclin repressor-like, C-terminal domain	1	1
HAD-like	NAD(P)-binding Rossmann-fold domains	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
F-box domain	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Ribosomal protein S8	Ribosomal protein L36	1	1
Acid proteases	Nucleic acid-binding proteins	1	1
beta-sandwich domain of Sec23/24	Acid proteases	1	1
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	1	1
DNA-glycosylase	Nudix	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
Ribosomal protein S2	F1F0 ATP synthase subunit A	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
L domain-like	V-type ATP synthase subunit C	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	RNA-binding domain, RBD	1	1
beta-beta-alpha zinc fingers	Ankyrin repeat	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Ribosomal protein L16p/L10e	Ribosomal protein L14	1	1
Phage fibre proteins	Ankyrin repeat	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
HCP-like	Argininosuccinate synthetase, C-terminal domain	1	1
Plant lectins/antimicrobial peptides	Barwin-like endoglucanases	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
Tricorn protease domain 2	alpha/beta-Hydrolases	1	1
"Winged helix" DNA-binding domain	UBA-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
alpha/beta-Hydrolases	HCP-like	1	1
NAC domain	NAC domain	1	1
"Winged helix" DNA-binding domain	Periplasmic binding protein-like II	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
FYVE/PHD zinc finger	Actin-like ATPase domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Methyl-accepting chemotaxis protein (MCP) signaling domain	1	1
ARM repeat	Acid proteases	1	1
gp5 N-terminal domain-like	alpha/beta-Hydrolases	1	1
PAH2 domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Ribonuclease H-like	Alkaline phosphatase-like	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
PUA domain-like	eIF1-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Protein kinase-like (PK-like)	1	1
Cyclin-like	L domain-like	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
PA domain	EGF/Laminin	1	1
Phosphoenolpyruvate/pyruvate domain	ENTH/VHS domain	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Oxysterol-binding protein-like	LeuD/IlvD-like	1	1
Nucleotidylyl transferase	tRNA-binding arm	1	1
POZ domain	Putative isomerase YbhE	1	1
Eukaryotic RPB5 N-terminal domain	Eukaryotic RPB5 N-terminal domain	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
ARM repeat	Ribosomal protein L4	1	1
F-box domain	FtsH protease domain-like	1	1
Terpenoid synthases	Protein kinase-like (PK-like)	1	1
Putative cyclase	YjgF-like	1	1
GroES-like	DNA/RNA polymerases	1	1
P-loop containing nucleoside triphosphate hydrolases	TK C-terminal domain-like	1	1
PDZ domain-like	Rubredoxin-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Thiamin diphosphate-binding fold (THDP-binding)	1	1
D-aminoacid aminotransferase-like PLP-dependent enzymes	D-aminoacid aminotransferase-like PLP-dependent enzymes	1	1
Homeodomain-like	F-box domain	1	1
lambda repressor-like DNA-binding domains	RmlC-like cupins	1	1
F-box domain	SET domain	1	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	1	1
DNA-glycosylase	DNase I-like	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
ACP-like	ACP-like	1	1
Six-hairpin glycosidases	Tautomerase/MIF	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Leucine zipper domain	Leucine zipper domain	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
PLP-dependent transferases	(Trans)glycosidases	1	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	1	1
Protein kinase-like (PK-like)	RuBisCo, C-terminal domain	1	1
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	1	1
Carbohydrate phosphatase	NAD(P)-binding Rossmann-fold domains	1	1
WGR domain-like	Phosphofructokinase	1	1
Ribosomal protein L14	Translational machinery components	1	1
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
gp5 N-terminal domain-like	gp5 N-terminal domain-like	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
POZ domain	Quinoprotein alcohol dehydrogenase-like	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
C-terminal domain of alpha and beta subunits of F1 ATP synthase	Cytochrome c oxidase subunit II-like, transmembrane region	1	1
HIT/MYND zinc finger-like	Protein kinase-like (PK-like)	1	1
Metallo-hydrolase/oxidoreductase	Protein kinase-like (PK-like)	1	1
Acyl-CoA dehydrogenase NM domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
GYF domain	RNA-binding domain, RBD	1	1
Protein kinase-like (PK-like)	Homeodomain-like	1	1
Protein kinase-like (PK-like)	HCP-like	1	1
HIT/MYND zinc finger-like	SET domain	1	1
GroES-like	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
Ribonuclease H-like	DNase I-like	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
NAD(P)-binding Rossmann-fold domains	DNA/RNA polymerases	1	1
Metallo-hydrolase/oxidoreductase	alpha/beta-Hydrolases	1	1
Concanavalin A-like lectins/glucanases	SH2 domain	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
F-box domain	Calcium-dependent phosphotriesterase	1	1
Leucine zipper domain	Chaperone J-domain	1	1
Aldolase	HAD-like	1	1
TPR-like	F-box domain	1	1
FAD/NAD(P)-binding domain	NosL/MerB-like	1	1
Tex N-terminal region-like	Nucleic acid-binding proteins	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	Cupredoxins	1	1
Protein kinase-like (PK-like)	Cytochrome P450	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Nucleic acid-binding proteins	SMAD/FHA domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	1	1
SPOC domain-like	SAP domain	1	1
"Winged helix" DNA-binding domain	GAF domain-like	1	1
Metalloproteases ("zincins"), catalytic domain	ARM repeat	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
WD40 repeat-like	P-loop containing nucleoside triphosphate hydrolases	1	1
HCP-like	Phospholipase D/nuclease	1	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
Protein prenylyltransferase	L domain-like	1	1
Nucleic acid-binding proteins	UBA-like	1	1
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	1	1
L domain-like	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Zn-binding ribosomal proteins	Ribosomal protein S18	1	1
WD40 repeat-like	Nucleoporin domain	1	1
Homeodomain-like	Toll/Interleukin receptor TIR domain	1	1
Putative isomerase YbhE	ARM repeat	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
NAD(P)-binding Rossmann-fold domains	Thiolase-like	1	1
RNI-like	WD40 repeat-like	1	1
Second domain of FERM	Prismane protein-like	1	1
Acid proteases	Acid proteases	1	1
L domain-like	Glutathione synthetase ATP-binding domain-like	1	1
ARM repeat	Concanavalin A-like lectins/glucanases	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
FAD/NAD(P)-binding domain	"Winged helix" DNA-binding domain	1	1
HMG-box	P-loop containing nucleoside triphosphate hydrolases	1	1
Thiolase-like	WD40 repeat-like	1	1
Cysteine proteinases	Thioredoxin-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
Tex N-terminal region-like	RuvA domain 2-like	1	1
Kix domain of CBP (creb binding protein)	Protein kinase-like (PK-like)	1	1
HSP20-like chaperones	HSP20-like chaperones	1	1
Zn-dependent exopeptidases	NAC domain	1	1
FAD-binding/transporter-associated domain-like	DNA-binding pseudobarrel domain	1	1
NAD(P)-binding Rossmann-fold domains	RNI-like	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Multidrug resistance efflux transporter EmrE	(Trans)glycosidases	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
Ada DNA repair protein, N-terminal domain (N-Ada 10)	Homeodomain-like	1	1
NAD(P)-binding Rossmann-fold domains	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
TPR-like	RNA-binding domain, RBD	1	1
RuBisCO, large subunit, small (N-terminal) domain	Ribosomal protein S8	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
Homeodomain-like	TATA-box binding protein-like	1	1
Mitochondrial carrier	Mitochondrial carrier	1	1
Ankyrin repeat	DNA/RNA polymerases	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	alpha-D-mannose-specific plant lectins	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
WD40 repeat-like	Cyclophilin-like	1	1
Acetyl-CoA synthetase-like	Tetracyclin repressor-like, C-terminal domain	1	1
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNA-binding pseudobarrel domain	Nucleic acid-binding proteins	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
F-box domain	DPP6 N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Thiamin diphosphate-binding fold (THDP-binding)	HAD-like	1	1
WD40 repeat-like	NHL repeat	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
Putative isomerase YbhE	RING/U-box	1	1
L domain-like	alpha/beta-Hydrolases	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
RNI-like	RuBisCo, C-terminal domain	1	1
Zn-dependent exopeptidases	Protein kinase-like (PK-like)	1	1
Phage fibre proteins	alpha/beta-Hydrolases	1	1
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	1	1
F-box domain	YWTD domain	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Metalloproteases ("zincins"), catalytic domain	OmpA-like	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	1	1
ARM repeat	BEACH domain	1	1
Ribulose-phoshate binding barrel	HAD-like	1	1
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin	1	1
WGR domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Cytochrome P450	Homeodomain-like	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
NAD(P)-binding Rossmann-fold domains	"Winged helix" DNA-binding domain	1	1
FYVE/PHD zinc finger	Bromodomain	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Nucleic acid-binding proteins	TPR-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	1	1
DNA-binding pseudobarrel domain	Ribonuclease H-like	1	1
HAD-like	RmlC-like cupins	1	1
FKBP-like	Triger factor/SurA peptide-binding domain-like	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
Retrovirus zinc finger-like domains	Actin depolymerizing proteins	1	1
EF-hand	TPR-like	1	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	1	1
Subunit IX of photosystem I reaction centre, PsaJ	Zn-binding ribosomal proteins	1	1
ISP domain	Chlorophyll a-b binding protein	1	1
Metallo-dependent phosphatases	Metallo-dependent phosphatases	1	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Macro domain-like	HIT-like	1	1
Ubiquitin-like	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Nucleic acid-binding proteins	Protein kinase-like (PK-like)	1	1
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	1	1
Pre-PUA domain	PUA domain-like	1	1
Poly A polymerase C-terminal region-like	Poly A polymerase C-terminal region-like	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
HIT/MYND zinc finger-like	L domain-like	1	1
MFS general substrate transporter	Alkaline phosphatase-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Thiolase-like	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Pili subunits	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Type II DNA topoisomerase	Type II DNA topoisomerase	1	1
R3H domain	Ankyrin repeat	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
Phosphofructokinase	"Winged helix" DNA-binding domain	1	1
ARM repeat	F-box domain	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
POZ domain	WD40 repeat-like	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
Translation proteins	PRC-barrel domain	1	1
GST C-terminal domain-like	Nucleic acid-binding proteins	1	1
Mog1p/PsbP-like	CRAL/TRIO domain	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
Subtilisin-like	Cytidine deaminase-like	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
RNI-like	NTF2-like	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	1	1
Pectin lyase-like	L domain-like	1	1
FYSH domain	beta-beta-alpha zinc fingers	1	1
Nucleic acid-binding proteins	F-box domain	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
Pseudo ankyrin repeat-like	TPR-like	1	1
PIN domain-like	Chromo domain-like	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Protease propeptides/inhibitors	PA domain	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
Lipocalins	Lipocalins	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
Acetyl-CoA synthetase-like	Homeodomain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
WD40 repeat-like	TPR-like	1	1
SAP domain	WGR domain-like	1	1
Ribosomal proteins S24e, L23 and L15e	Translation proteins SH3-like domain	1	1
Phage tail proteins	Ankyrin repeat	1	1
Ankyrin repeat	Translation initiation factor IF3, C-terminal domain	1	1
FAD/NAD(P)-binding domain	Thioredoxin-like	1	1
MetI-like	P-loop containing nucleoside triphosphate hydrolases	1	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Quinoprotein alcohol dehydrogenase-like	DPP6 N-terminal domain-like	1	1
beta-sandwich domain of Sec23/24	Ribosomal protein L1	1	1
Phosphoenolpyruvate/pyruvate domain	Multidrug resistance efflux transporter EmrE	1	1
"Winged helix" DNA-binding domain	Acetyl-CoA synthetase-like	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
Chromo domain-like	Ankyrin repeat	1	1
Terpenoid synthases	Terpenoid synthases	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Cap-Gly domain	L domain-like	1	1
Band 7/SPFH domain	Band 7/SPFH domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT-like	1	1
JAB1/MPN domain	cAMP-binding domain-like	1	1
ClpP/crotonase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
DNase I-like	Clavaminate synthase-like	1	1
"Winged helix" DNA-binding domain	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
Metallo-hydrolase/oxidoreductase	TPR-like	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
UBC-like	UBC-like	1	1
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	1	1
Photosystem II antenna protein-like	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
Acyl-CoA dehydrogenase C-terminal domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
TK C-terminal domain-like	NAD(P)-binding Rossmann-fold domains	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Arabinanase/levansucrase/invertase	Arabinanase/levansucrase/invertase	1	1
P-loop containing nucleoside triphosphate hydrolases	Typo IV secretion system protein TraC	1	1
ARM repeat	"Winged helix" DNA-binding domain	1	1
Ribonuclease H-like	Protein kinase-like (PK-like)	1	1
ACP-like	Heme-dependent catalase-like	1	1
FAD-binding/transporter-associated domain-like	FAD-binding/transporter-associated domain-like	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
PDZ domain-like	E set domains	1	1
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	1	1
HAD-like	Nucleotide-diphospho-sugar transferases	1	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
TPR-like	Casein kinase II beta subunit	1	1
DNA/RNA polymerases	DNA/RNA polymerases	1	1
Zn-dependent exopeptidases	L domain-like	1	1
Photosystem II 10 kDa phosphoprotein PsbH	Transmembrane di-heme cytochromes	1	1
HCP-like	RNI-like	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
L domain-like	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	1	1
DPP6 N-terminal domain-like	HCP-like	1	1
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	1	1
Concanavalin A-like lectins/glucanases	Cysteine proteinases	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
Photosystem II reaction center protein K, PsbK	Photosystem II reaction center protein I, PsbI	1	1
C-terminal domain of alpha and beta subunits of F1 ATP synthase	Cupredoxins	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
Cna protein B-type domain	Starch-binding domain-like	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
Acyl-CoA N-acyltransferases (Nat)	RNA-binding domain, RBD	1	1
F-box domain	Pectin lyase-like	1	1
Homeodomain-like	Photosystem I subunits PsaA/PsaB	1	1
TATA-box binding protein-like	DNA-glycosylase	1	1
Bromodomain	Nucleic acid-binding proteins	1	1
Quinoprotein alcohol dehydrogenase-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
Caspase-like	DNase I-like	1	1
P-loop containing nucleoside triphosphate hydrolases	NTF2-like	1	1
ssDNA-binding transcriptional regulator domain	ssDNA-binding transcriptional regulator domain	1	1
Ribonuclease Rh-like	Formin homology 2 domain (FH2 domain)	1	1
AF0104/ALDC/Ptd012-like	AF0104/ALDC/Ptd012-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
Protein kinase-like (PK-like)	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	1	1
TolB, C-terminal domain	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Skp1 dimerisation domain-like	Skp1 dimerisation domain-like	1	1
vWA-like	SAP domain	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	"Winged helix" DNA-binding domain	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
Aquaporin-like	P-loop containing nucleoside triphosphate hydrolases	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
Phage fibre proteins	Tricorn protease N-terminal domain	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
RNI-like	alpha/beta-Hydrolases	1	1
PA domain	RING/U-box	1	1
SMI1/KNR4-like	ApaG-like	1	1
UBC-like	Class II aaRS ABD-related	1	1
Ankyrin repeat	Pseudo ankyrin repeat-like	1	1
FYVE/PHD zinc finger	F-box domain	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
PLP-dependent transferases	Clavaminate synthase-like	1	1
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
gp5 N-terminal domain-like	Tricorn protease N-terminal domain	1	1
L domain-like	Actin-crosslinking proteins	1	1
Protein kinase-like (PK-like)	Metal cation-transporting ATPase, ATP-binding domain N	1	1
L domain-like	ARM repeat	1	1
Multidrug resistance efflux transporter EmrE	ENTH/VHS domain	1	1
Single hybrid motif	ClpP/crotonase	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
Aconitase iron-sulfur domain	Oxysterol-binding protein-like	1	1
Ubiquitin-like	P-loop containing nucleoside triphosphate hydrolases	1	1
alpha/beta-Hydrolases	Ankyrin repeat	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
CheY-like	DNA-binding domain	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
F-box domain	LysM domain	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
C-terminal UvrC-binding domain of UvrB	ApaG-like	1	1
"Winged helix" DNA-binding domain	NosL/MerB-like	1	1
Cysteine proteinases	DNA-binding pseudobarrel domain	1	1
Ribonuclease H-like	SH2 domain	1	1
TolB, C-terminal domain	Quinoprotein alcohol dehydrogenase-like	1	1
Toll/Interleukin receptor TIR domain	DNA-binding pseudobarrel domain	1	1
Cullin repeat-like	WRKY DNA-binding domain	1	1
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	alpha/beta-Hydrolases	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
Sec1/munc18-like (SM) proteins	Sec1/munc18-like (SM) proteins	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
WD40 repeat-like	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
TPR-like	Calcium-dependent phosphotriesterase	1	1
RNI-like	beta and beta-prime subunits of DNA dependent RNA-polymerase	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	MHC antigen-recognition domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	1	1
Ribonuclease H-like	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA breaking-rejoining enzymes	Heat shock protein 70kD (HSP70), peptide-binding domain	1	1
L domain-like	RING/U-box	1	1
Nucleic acid-binding proteins	L domain-like	1	1
ALDH-like	TPR-like	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
TPR-like	FAD/NAD(P)-binding domain	1	1
WD40 repeat-like	3-carboxy-cis,cis-mucoante lactonizing enzyme	1	1
Terpenoid synthases	L domain-like	1	1
ISP transmembrane anchor	ISP domain	1	1
ARID-like	Homeodomain-like	1	1
Chaperone J-domain	Multiheme cytochromes	1	1
Starch-binding domain-like	Carboxypeptidase regulatory domain-like	1	1
TK C-terminal domain-like	HAD-like	1	1
MIT domain	MIT domain	1	1
alpha/beta-Hydrolases	FAD/NAD(P)-binding domain	1	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	1	1
DAK1/DegV-like	DhaL-like	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
Thiamin diphosphate-binding fold (THDP-binding)	NAD(P)-binding Rossmann-fold domains	1	1
Cullin repeat-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Rad51 N-terminal domain-like	ARM repeat	1	1
Carbohydrate phosphatase	TK C-terminal domain-like	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
Phosphofructokinase	P-loop containing nucleoside triphosphate hydrolases	1	1
DNA repair protein MutS, domain I	GIY-YIG endonuclease	1	1
Pectin lyase-like	RmlC-like cupins	1	1
Phage tail proteins	alpha/beta-Hydrolases	1	1
Nucleic acid-binding proteins	DNA-binding domain	1	1
MHC antigen-recognition domain	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	HAD-like	1	1
HMG-box	Leucine zipper domain	1	1
WGR domain-like	NAD(P)-binding Rossmann-fold domains	1	1
HD-domain/PDEase-like	ACT-like	1	1
MHC antigen-recognition domain	ARM repeat	1	1
SGNH hydrolase	SGNH hydrolase	1	1
P-loop containing nucleoside triphosphate hydrolases	Cysteine proteinases	1	1
Ran binding protein zinc finger-like	DNase I-like	1	1
(Phosphotyrosine protein) phosphatases II	RNA-binding domain, RBD	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
F-box domain	ApaG-like	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Ribonuclease Rh-like	Ribonuclease Rh-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Ribonuclease Rh-like	1	1
FAD/NAD(P)-binding domain	Nucleic acid-binding proteins	1	1
Phosphofructokinase	NAD(P)-binding Rossmann-fold domains	1	1
WD40 repeat-like	Toll/Interleukin receptor TIR domain	1	1
L domain-like	FabD/lysophospholipase-like	1	1
Thioredoxin-like	Ribonuclease Rh-like	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	1	1
TPR-like	Phospholipase D/nuclease	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
F-box domain	Outer arm dynein light chain 1	1	1
SWIB/MDM2 domain	eIF1-like	1	1
Periplasmic binding protein-like II	MetI-like	1	1
HydA/Nqo6-like	Nqo5-like	1	1
FAD-linked reductases, C-terminal domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
Kix domain of CBP (creb binding protein)	Kix domain of CBP (creb binding protein)	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
GAF domain-like	Acetyl-CoA synthetase-like	1	1
Carbohydrate phosphatase	Thiamin diphosphate-binding fold (THDP-binding)	1	1
Cysteine-rich domain	Caspase-like	1	1
Terpenoid synthases	Outer arm dynein light chain 1	1	1
Carbamate kinase-like	Carbamate kinase-like	1	1
Cytochrome b5-like heme/steroid binding domain	alpha/beta-Hydrolases	1	1
UBA-like	post-AAA+ oligomerization domain-like	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1