All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
P-loop containing nucleoside triphosphate hydrolases | L domain-like | 873 | 131 |  |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 470 | 94 |  |
L domain-like | L domain-like | 469 | 109 |  |
L domain-like | Protein kinase-like (PK-like) | 446 | 48 |  |
Toll/Interleukin receptor TIR domain | P-loop containing nucleoside triphosphate hydrolases | 423 | 73 |  |
F-box domain | RNI-like | 383 | 18 |  |
Toll/Interleukin receptor TIR domain | L domain-like | 361 | 62 |  |
L domain-like | RNI-like | 333 | 107 |  |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 310 | 65 |  |
"Winged helix" DNA-binding domain | L domain-like | 253 | 51 |  |
Toll/Interleukin receptor TIR domain | "Winged helix" DNA-binding domain | 253 | 48 |  |
RNA-binding domain, RBD | RNA-binding domain, RBD | 208 | 26 |  |
alpha-D-mannose-specific plant lectins | Protein kinase-like (PK-like) | 201 | 12 |  |
P-loop containing nucleoside triphosphate hydrolases | RNI-like | 182 | 60 |  |
Actin-like ATPase domain | Actin-like ATPase domain | 145 | 24 |  |
RNI-like | RNI-like | 144 | 53 |  |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 137 | 13 |  |
ABC transporter transmembrane region | ABC transporter transmembrane region | 110 | 9 |  |
F-box domain | Galactose oxidase, central domain | 105 | 5 |  |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 102 | 25 |  |
RNI-like | Protein kinase-like (PK-like) | 101 | 29 |  |
GroES-like | NAD(P)-binding Rossmann-fold domains | 96 | 7 |  |
TPR-like | TPR-like | 95 | 26 |  |
Thioredoxin-like | GST C-terminal domain-like | 95 | 7 |  |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 93 | 7 |  |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 92 | 17 |  |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 92 | 22 |  |
Calcium ATPase, transmembrane domain M | HAD-like | 91 | 17 |  |
Calcium ATPase, transduction domain A | HAD-like | 88 | 15 |  |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 81 | 14 |  |
RING/U-box | ARM repeat | 74 | 10 |  |
ARM repeat | ARM repeat | 73 | 34 |  |
Thiolase-like | Thiolase-like | 72 | 3 |  |
Cyclin-like | Cyclin-like | 71 | 8 |  |
DNA-binding pseudobarrel domain | DNA-binding pseudobarrel domain | 69 | 13 |  |
"Winged helix" DNA-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 66 | 2 |  |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 66 | 9 |  |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 66 | 9 |  |
S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 65 | 5 |  |
(Trans)glycosidases | Galactose-binding domain-like | 63 | 12 |  |
Plant invertase/pectin methylesterase inhibitor | Pectin lyase-like | 63 | 2 |  |
RING/U-box | RING/U-box | 58 | 20 |  |
Metal cation-transporting ATPase, ATP-binding domain N | HAD-like | 57 | 7 |  |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 56 | 9 |  |
Metal cation-transporting ATPase, ATP-binding domain N | Calcium ATPase, transmembrane domain M | 56 | 6 |  |
CRAL/TRIO N-terminal domain | CRAL/TRIO domain | 54 | 6 |  |
Periplasmic binding protein-like I | Periplasmic binding protein-like II | 54 | 5 |  |
Cupredoxins | Cupredoxins | 54 | 5 |  |
POZ domain | Skp1 dimerisation domain-like | 53 | 4 |  |
Calcium ATPase, transduction domain A | Metal cation-transporting ATPase, ATP-binding domain N | 53 | 4 |  |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid synthases | 53 | 5 |  |
Concanavalin A-like lectins/glucanases | Protein kinase-like (PK-like) | 50 | 9 |  |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 50 | 8 |  |
Toll/Interleukin receptor TIR domain | Toll/Interleukin receptor TIR domain | 49 | 18 |  |
(Trans)glycosidases | Glycosyl hydrolase domain | 48 | 11 |  |
Barwin-like endoglucanases | PHL pollen allergen | 47 | 1 |  |
F-box domain | L domain-like | 47 | 10 |  |
Homeodomain-like | Homeodomain-like | 46 | 14 |  |
Voltage-gated potassium channels | cAMP-binding domain-like | 46 | 5 |  |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 45 | 9 |  |
CheY-like | Homeodomain-like | 45 | 5 |  |
Protein kinase-like (PK-like) | EF-hand | 44 | 2 |  |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 43 | 11 |  |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 42 | 6 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 42 | 6 |  |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 41 | 8 |  |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 41 | 5 |  |
CCCH zinc finger | CCCH zinc finger | 40 | 17 |  |
Ubiquitin-like | Ubiquitin-like | 40 | 10 |  |
DNA-binding domain | DNA-binding domain | 39 | 5 |  |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 39 | 5 |  |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipoxigenase | 38 | 2 |  |
RNA-binding domain, RBD | Ran binding protein zinc finger-like | 38 | 3 |  |
F-box domain | Kelch motif | 38 | 6 |  |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 37 | 6 |  |
FYVE/PHD zinc finger | FYVE/PHD zinc finger | 37 | 18 |  |
Eukaryotic type KH-domain (KH-domain type I) | Eukaryotic type KH-domain (KH-domain type I) | 36 | 14 |  |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 36 | 8 |  |
Galactose-binding domain-like | Galactose-binding domain-like | 36 | 4 |  |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 36 | 12 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | C2 domain (Calcium/lipid-binding domain, CaLB) | 35 | 7 |  |
ACT-like | ACT-like | 33 | 12 |  |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 32 | 6 |  |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 30 | 6 |  |
(Trans)glycosidases | Beta-D-glucan exohydrolase, C-terminal domain | 29 | 2 |  |
PUA domain-like | SET domain | 29 | 3 |  |
ENTH/VHS domain | GAT-like domain | 29 | 3 |  |
vWA-like | RING/U-box | 28 | 4 |  |
DNA-binding pseudobarrel domain | CAD & PB1 domains | 28 | 4 |  |
RING/U-box | Nucleotide-diphospho-sugar transferases | 28 | 3 |  |
WRKY DNA-binding domain | WRKY DNA-binding domain | 28 | 2 |  |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 27 | 7 |  |
Cullin homology domain | "Winged helix" DNA-binding domain | 27 | 4 |  |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 27 | 3 |  |
Purple acid phosphatase, N-terminal domain | Metallo-dependent phosphatases | 27 | 4 |  |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 26 | 7 |  |
ACT-like | Protein kinase-like (PK-like) | 26 | 2 |  |
Surp module (SWAP domain) | Surp module (SWAP domain) | 26 | 3 |  |
beta-beta-alpha zinc fingers | beta-beta-alpha zinc fingers | 26 | 15 |  |
Phospholipase D/nuclease | Phospholipase D/nuclease | 25 | 9 |  |
HMA, heavy metal-associated domain | HMA, heavy metal-associated domain | 25 | 10 |  |
FYVE/PHD zinc finger | Acyl-CoA N-acyltransferases (Nat) | 25 | 8 |  |
GroEL apical domain-like | GroEL equatorial domain-like | 24 | 6 |  |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 24 | 5 |  |
PAH2 domain | PAH2 domain | 24 | 7 |  |
P-loop containing nucleoside triphosphate hydrolases | E set domains | 24 | 4 |  |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | SAICAR synthase-like | 24 | 6 |  |
Adenine nucleotide alpha hydrolases-like | Protein kinase-like (PK-like) | 23 | 4 |  |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 23 | 4 |  |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 23 | 4 |  |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 23 | 4 |  |
Homeodomain-like | Bet v1-like | 23 | 6 |  |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 23 | 8 |  |
Clc chloride channel | CBS-domain pair | 23 | 4 |  |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 22 | 10 |  |
GroES-like | GroES-like | 22 | 2 |  |
CBS-domain pair | CBS-domain pair | 22 | 8 |  |
GroEL-intermediate domain like | GroEL apical domain-like | 22 | 5 |  |
GroEL-intermediate domain like | GroEL equatorial domain-like | 22 | 5 |  |
Ankyrin repeat | Ankyrin repeat | 22 | 5 |  |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 22 | 7 |  |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 22 | 5 |  |
Thioredoxin-like | Thioredoxin-like | 22 | 12 |  |
PAZ domain | Ribonuclease H-like | 22 | 4 |  |
Ribonuclease H-like | DNA/RNA polymerases | 22 | 4 |  |
EF-hand | Riboflavin synthase domain-like | 22 | 2 |  |
Ypt/Rab-GAP domain of gyp1p | Ypt/Rab-GAP domain of gyp1p | 22 | 5 |  |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 21 | 5 |  |
Homodimeric domain of signal transducing histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 21 | 6 |  |
Subtilisin-like | PA domain | 21 | 4 |  |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 21 | 9 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Glucocorticoid receptor-like (DNA-binding domain) | 21 | 8 |  |
FKBP-like | FKBP-like | 21 | 8 |  |
Amine oxidase N-terminal region | Amine oxidase catalytic domain | 21 | 3 |  |
E set domains | Ankyrin repeat | 21 | 2 |  |
Ankyrin repeat | P-loop containing nucleoside triphosphate hydrolases | 21 | 4 |  |
dsRNA-binding domain-like | dsRNA-binding domain-like | 21 | 9 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | CheY-like | 20 | 6 |  |
ARM repeat | Protein kinase-like (PK-like) | 20 | 17 |  |
Homodimeric domain of signal transducing histidine kinase | CheY-like | 20 | 6 |  |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 20 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 20 | 7 |  |
PAP/OAS1 substrate-binding domain | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 20 | 1 |  |
Amine oxidase N-terminal region | Amine oxidase N-terminal region | 20 | 3 |  |
Bet v1-like | Bet v1-like | 20 | 6 |  |
SNARE-like | SNARE fusion complex | 20 | 2 |  |
Nucleotidyltransferase | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 20 | 1 |  |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 20 | 7 |  |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 20 | 8 |  |
Translation proteins | EF-G C-terminal domain-like | 20 | 7 |  |
Double Clp-N motif | P-loop containing nucleoside triphosphate hydrolases | 20 | 8 |  |
Homeodomain-like | "Winged helix" DNA-binding domain | 20 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | EF-hand | 20 | 5 |  |
WD40 repeat-like | WD40 repeat-like | 19 | 11 |  |
Cullin repeat-like | Cullin homology domain | 19 | 4 |  |
Zinc hairpin stack | RING/U-box | 19 | 5 |  |
FKBP-like | TPR-like | 19 | 4 |  |
Protein kinase-like (PK-like) | Protein kinase-like (PK-like) | 18 | 13 |  |
Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 18 | 3 |  |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 18 | 7 |  |
RING/U-box | Protein kinase-like (PK-like) | 18 | 6 |  |
RING/U-box | FYVE/PHD zinc finger | 18 | 9 |  |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 18 | 3 |  |
Chromo domain-like | Chromo domain-like | 18 | 3 |  |
TRAF domain-like | Ubiquitin-like | 18 | 2 |  |
CHY zinc finger-like | RING/U-box | 18 | 4 |  |
CHY zinc finger-like | Zinc hairpin stack | 18 | 4 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 18 | 11 |  |
Composite domain of metallo-dependent hydrolases | Metallo-dependent hydrolases | 17 | 6 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Phospholipase D/nuclease | 17 | 4 |  |
PK beta-barrel domain-like | PK C-terminal domain-like | 17 | 2 |  |
EF-hand | Ferredoxin reductase-like, C-terminal NADP-linked domain | 17 | 1 |  |
EGF/Laminin | Protein kinase-like (PK-like) | 17 | 5 |  |
Ran binding protein zinc finger-like | Ran binding protein zinc finger-like | 17 | 11 |  |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 17 | 5 |  |
P-loop containing nucleoside triphosphate hydrolases | RING/U-box | 17 | 5 |  |
Chromo domain-like | P-loop containing nucleoside triphosphate hydrolases | 17 | 2 |  |
ARM repeat | Hect, E3 ligase catalytic domain | 17 | 4 |  |
F-box domain | Tubby C-terminal domain-like | 17 | 3 |  |
Acid proteases | Saposin | 17 | 1 |  |
FYVE/PHD zinc finger | SET domain | 17 | 10 |  |
TATA-box binding protein-like | TATA-box binding protein-like | 16 | 2 |  |
Starch-binding domain-like | Galactose-binding domain-like | 16 | 3 |  |
TPR-like | HCP-like | 16 | 12 |  |
YhbY-like | YhbY-like | 16 | 6 |  |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 16 | 4 |  |
Cullin repeat-like | "Winged helix" DNA-binding domain | 16 | 2 |  |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 16 | 5 |  |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 16 | 9 |  |
FAS1 domain | FAS1 domain | 16 | 3 |  |
Protein kinase-like (PK-like) | TPR-like | 15 | 3 |  |
dsRNA-binding domain-like | P-loop containing nucleoside triphosphate hydrolases | 15 | 5 |  |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 15 | 3 |  |
Galactose mutarotase-like | (Trans)glycosidases | 15 | 3 |  |
Translation proteins | Ribosomal protein S5 domain 2-like | 15 | 4 |  |
Cryptochrome/photolyase, N-terminal domain | Cryptochrome/photolyase FAD-binding domain | 15 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | Sec63 N-terminal domain-like | 15 | 9 |  |
Arabinanase/levansucrase/invertase | Concanavalin A-like lectins/glucanases | 15 | 2 |  |
Protein kinase-like (PK-like) | WD40 repeat-like | 15 | 4 |  |
Glucocorticoid receptor-like (DNA-binding domain) | AN1-like Zinc finger | 15 | 2 |  |
Nucleic acid-binding proteins | Translation proteins SH3-like domain | 15 | 4 |  |
EF-hand | EF-hand | 15 | 7 |  |
Ankyrin repeat | RING/U-box | 15 | 5 |  |
UDP-Glycosyltransferase/glycogen phosphorylase | HAD-like | 15 | 3 |  |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 14 | 6 |  |
PA domain | Zn-dependent exopeptidases | 14 | 3 |  |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 14 | 10 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 14 | 6 |  |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 14 | 3 |  |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 14 | 7 |  |
SNARE-like | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 14 | 2 |  |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 14 | 2 |  |
Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 14 | 3 |  |
HCP-like | HCP-like | 14 | 7 |  |
NTF2-like | RNA-binding domain, RBD | 14 | 2 |  |
Homeodomain-like | FAD-linked reductases, C-terminal domain | 14 | 2 |  |
Galactose mutarotase-like | Glycosyl hydrolase domain | 14 | 2 |  |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 14 | 9 |  |
Homeodomain-like | FAD/NAD(P)-binding domain | 14 | 2 |  |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 14 | 4 |  |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 14 | 10 |  |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 14 | 7 |  |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 13 | 2 |  |
RING/U-box | TRAF domain-like | 13 | 3 |  |
E set domains | (Trans)glycosidases | 13 | 6 |  |
Toll/Interleukin receptor TIR domain | RNI-like | 13 | 9 |  |
ARM repeat | WD40 repeat-like | 13 | 10 |  |
F-box domain | F-box domain | 13 | 7 |  |
Protease propeptides/inhibitors | Subtilisin-like | 13 | 3 |  |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 13 | 5 |  |
Calponin-homology domain, CH-domain | P-loop containing nucleoside triphosphate hydrolases | 13 | 2 |  |
(Trans)glycosidases | Ricin B-like lectins | 13 | 3 |  |
Tropomyosin | Tropomyosin | 13 | 4 |  |
Carbamate kinase-like | ACT-like | 13 | 4 |  |
Transducin (alpha subunit), insertion domain | P-loop containing nucleoside triphosphate hydrolases | 13 | 3 |  |
PGBD-like | Metalloproteases ("zincins"), catalytic domain | 13 | 2 |  |
Ubiquitin-like | UBA-like | 13 | 6 |  |
MFS general substrate transporter | MFS general substrate transporter | 12 | 2 |  |
Protein kinase-like (PK-like) | Ankyrin repeat | 12 | 3 |  |
Trypsin-like serine proteases | PDZ domain-like | 12 | 5 |  |
ClpP/crotonase | ClpP/crotonase | 12 | 5 |  |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 12 | 7 |  |
Helical domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 12 | 4 |  |
HMA, heavy metal-associated domain | HAD-like | 12 | 9 |  |
PYP-like sensor domain (PAS domain) | Protein kinase-like (PK-like) | 12 | 3 |  |
EF-hand | PLC-like phosphodiesterases | 12 | 3 |  |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 12 | 2 |  |
POZ domain | Ankyrin repeat | 12 | 4 |  |
RNase III domain-like | dsRNA-binding domain-like | 11 | 6 |  |
Class II aaRS and biotin synthetases | GAD domain-like | 11 | 3 |  |
WD40 repeat-like | Quinoprotein alcohol dehydrogenase-like | 11 | 10 |  |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 11 | 1 |  |
HAD-like | BRCT domain | 11 | 3 |  |
BAR/IMD domain-like | SH3-domain | 11 | 1 |  |
Flavoproteins | Ferredoxin reductase-like, C-terminal NADP-linked domain | 11 | 3 |  |
Eukaryotic RPB5 N-terminal domain | RPB5-like RNA polymerase subunit | 11 | 2 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 11 | 5 |  |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 11 | 4 |  |
Flavoproteins | Riboflavin synthase domain-like | 11 | 3 |  |
"Winged helix" DNA-binding domain | Sec63 N-terminal domain-like | 11 | 5 |  |
E set domains | Glycosyl hydrolase domain | 11 | 5 |  |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 11 | 5 |  |
(Phosphotyrosine protein) phosphatases II | C2 domain (Calcium/lipid-binding domain, CaLB) | 11 | 4 |  |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 11 | 1 |  |
GAF domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 11 | 4 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | EF-hand | 11 | 2 |  |
NAD-binding domain of HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | 11 | 1 |  |
Tudor/PWWP/MBT | FYVE/PHD zinc finger | 10 | 5 |  |
Zn-finger domain of Sec23/24 | vWA-like | 10 | 4 |  |
WD40 repeat-like | RING/U-box | 10 | 6 |  |
RING/U-box | Homeodomain-like | 10 | 3 |  |
ARM repeat | Sec7 domain | 10 | 5 |  |
Smc hinge domain | P-loop containing nucleoside triphosphate hydrolases | 10 | 5 |  |
ATP-dependent DNA ligase DNA-binding domain | DNA ligase/mRNA capping enzyme, catalytic domain | 10 | 5 |  |
RCC1/BLIP-II | RCC1/BLIP-II | 10 | 4 |  |
POZ domain | TRAF domain-like | 10 | 2 |  |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 10 | 4 |  |
BRCT domain | BRCT domain | 10 | 8 |  |
beta-sandwich domain of Sec23/24 | vWA-like | 10 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | FYVE/PHD zinc finger | 10 | 5 |  |
PLC-like phosphodiesterases | C2 domain (Calcium/lipid-binding domain, CaLB) | 10 | 2 |  |
beta-sandwich domain of Sec23/24 | Zn-finger domain of Sec23/24 | 10 | 4 |  |
vWA-like | Helical domain of Sec23/24 | 10 | 4 |  |
Sec63 N-terminal domain-like | E set domains | 10 | 4 |  |
beta-sandwich domain of Sec23/24 | Helical domain of Sec23/24 | 10 | 4 |  |
Galactose-binding domain-like | Galactose mutarotase-like | 10 | 3 |  |
t-snare proteins | SNARE fusion complex | 10 | 3 |  |
PH domain-like | Oxysterol-binding protein-like | 10 | 1 |  |
Zn-finger domain of Sec23/24 | Helical domain of Sec23/24 | 10 | 4 |  |
Glutathione synthetase ATP-binding domain-like | Phosphoglycerate mutase-like | 10 | 3 |  |
TPR-like | Chaperone J-domain | 10 | 4 |  |
UBA-like | UBA-like | 9 | 7 |  |
WW domain | WW domain | 9 | 5 |  |
RmlC-like cupins | RmlC-like cupins | 9 | 2 |  |
Zn-finger domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 9 | 3 |  |
vWA-like | C-terminal, gelsolin-like domain of Sec23/24 | 9 | 3 |  |
ARID-like | FYVE/PHD zinc finger | 9 | 3 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 9 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | PRTase-like | 9 | 1 |  |
"Winged helix" DNA-binding domain | RNI-like | 9 | 6 |  |
(Phosphotyrosine protein) phosphatases II | Formin homology 2 domain (FH2 domain) | 9 | 2 |  |
Homeodomain-like | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 9 | 2 |  |
Tudor/PWWP/MBT | SET domain | 9 | 4 |  |
ARM repeat | P-loop containing nucleoside triphosphate hydrolases | 9 | 5 |  |
PreATP-grasp domain | Rudiment single hybrid motif | 9 | 5 |  |
Chromo domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 9 | 1 |  |
CCCH zinc finger | RNA-binding domain, RBD | 9 | 4 |  |
Sigma2 domain of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 9 | 3 |  |
Galactose mutarotase-like | Starch-binding domain-like | 9 | 2 |  |
ISP domain | Bet v1-like | 9 | 3 |  |
RING/U-box | Cysteine proteinases | 9 | 5 |  |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 9 | 4 |  |
RuBisCO, large subunit, small (N-terminal) domain | RuBisCo, C-terminal domain | 9 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 9 | 5 |  |
Galactose oxidase, central domain | E set domains | 9 | 2 |  |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 9 | 4 |  |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 9 | 7 |  |
E set domains | CBS-domain pair | 9 | 2 |  |
RNase III domain-like | RNase III domain-like | 9 | 6 |  |
ARM repeat | POZ domain | 9 | 4 |  |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 9 | 3 |  |
beta-sandwich domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 9 | 3 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Formin homology 2 domain (FH2 domain) | 9 | 2 |  |
HD-domain/PDEase-like | Nucleotidyltransferase | 9 | 6 |  |
Cysteine proteinases | UBA-like | 9 | 3 |  |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 9 | 5 |  |
CAD & PB1 domains | Protein kinase-like (PK-like) | 8 | 1 |  |
EF-hand | Voltage-gated potassium channels | 8 | 3 |  |
Nucleic acid-binding proteins | GAD domain-like | 8 | 2 |  |
Initiation factor IF2/eIF5b, domain 3 | Translation proteins | 8 | 4 |  |
Adenine nucleotide alpha hydrolases-like | RING/U-box | 8 | 1 |  |
Single hybrid motif | CoA-dependent acyltransferases | 8 | 4 |  |
NAD(P)-binding Rossmann-fold domains | ACT-like | 8 | 4 |  |
E set domains | AMPKBI-like | 8 | 2 |  |
L domain-like | Formin homology 2 domain (FH2 domain) | 8 | 2 |  |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 8 | 4 |  |
Cysteine proteinases | Granulin repeat | 8 | 2 |  |
Actin-crosslinking proteins | (Trans)glycosidases | 8 | 1 |  |
DUSP-like | Cysteine proteinases | 8 | 3 |  |
Nucleotidylyl transferase | Nucleotidylyl transferase | 8 | 1 |  |
ATP-dependent DNA ligase DNA-binding domain | Nucleic acid-binding proteins | 8 | 3 |  |
HIT/MYND zinc finger-like | Cysteine proteinases | 8 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 8 | 4 |  |
Protein kinase-like (PK-like) | Formin homology 2 domain (FH2 domain) | 8 | 2 |  |
N-terminal, heterodimerisation domain of RBP7 (RpoE) | Nucleic acid-binding proteins | 8 | 1 |  |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 8 | 4 |  |
FAD/NAD(P)-binding domain | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 8 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | CYTH-like phosphatases | 8 | 3 |  |
DNA-binding pseudobarrel domain | P-loop containing nucleoside triphosphate hydrolases | 8 | 6 |  |
ADC-like | Cdc48 domain 2-like | 8 | 4 |  |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 8 | 3 |  |
FAD-linked reductases, C-terminal domain | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 8 | 1 |  |
LysM domain | Protein kinase-like (PK-like) | 8 | 2 |  |
SET domain | RuBisCo LSMT C-terminal, substrate-binding domain | 8 | 3 |  |
POZ domain | POZ domain | 8 | 6 |  |
Actin depolymerizing proteins | Actin depolymerizing proteins | 8 | 4 |  |
(Trans)glycosidases | Chitinase insertion domain | 8 | 4 |  |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 8 | 2 |  |
Zinc beta-ribbon | Cyclin-like | 8 | 2 |  |
CheY-like | CheY-like | 8 | 1 |  |
PH domain-like | Bet v1-like | 7 | 2 |  |
Nucleoside hydrolase | Nucleoside hydrolase | 7 | 3 |  |
TAZ domain | FYVE/PHD zinc finger | 7 | 3 |  |
ArfGap/RecO-like zinc finger | C2 domain (Calcium/lipid-binding domain, CaLB) | 7 | 3 |  |
Periplasmic binding protein-like II | ACT-like | 7 | 1 |  |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 7 | 4 |  |
FAD-binding/transporter-associated domain-like | Molybdenum cofactor-binding domain | 7 | 2 |  |
CO dehydrogenase ISP C-domain like | Molybdenum cofactor-binding domain | 7 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | RNase III domain-like | 7 | 5 |  |
RCC1/BLIP-II | FYVE/PHD zinc finger | 7 | 2 |  |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 7 | 3 |  |
PDZ domain-like | ClpP/crotonase | 7 | 1 |  |
CO dehydrogenase flavoprotein C-terminal domain-like | Molybdenum cofactor-binding domain | 7 | 2 |  |
ENT-like | Tudor/PWWP/MBT | 7 | 2 |  |
Families 57/38 glycoside transferase middle domain | Galactose mutarotase-like | 7 | 4 |  |
TPR-like | CAD & PB1 domains | 7 | 2 |  |
CO dehydrogenase ISP C-domain like | CO dehydrogenase flavoprotein C-terminal domain-like | 7 | 2 |  |
RCC1/BLIP-II | Protein kinase-like (PK-like) | 7 | 4 |  |
RNA-binding domain, RBD | PABC (PABP) domain | 7 | 3 |  |
FAD-binding/transporter-associated domain-like | CO dehydrogenase flavoprotein C-terminal domain-like | 7 | 2 |  |
Concanavalin A-like lectins/glucanases | P-domain of calnexin/calreticulin | 7 | 1 |  |
ARID-like | HMG-box | 7 | 4 |  |
alpha-ketoacid dehydrogenase kinase, N-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 7 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | PAZ domain | 7 | 5 |  |
Class II aaRS and biotin synthetases | C-terminal domain of ProRS | 7 | 2 |  |
CO dehydrogenase ISP C-domain like | CO dehydrogenase molybdoprotein N-domain-like | 7 | 2 |  |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 7 | 3 |  |
Surp module (SWAP domain) | Ubiquitin-like | 7 | 1 |  |
DNase I-like | EF-hand | 7 | 4 |  |
PH domain-like | P-loop containing nucleoside triphosphate hydrolases | 7 | 3 |  |
TRAF domain-like | Cysteine proteinases | 7 | 2 |  |
L domain-like | Actin-like ATPase domain | 7 | 6 |  |
Dihydrofolate reductase-like | Thymidylate synthase/dCMP hydroxymethylase | 7 | 1 |  |
FAD-binding/transporter-associated domain-like | CO dehydrogenase molybdoprotein N-domain-like | 7 | 2 |  |
"Winged helix" DNA-binding domain | E set domains | 7 | 3 |  |
PH domain-like | FYVE/PHD zinc finger | 7 | 2 |  |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 7 | 4 |  |
Class II aaRS ABD-related | C-terminal domain of ProRS | 7 | 2 |  |
"Winged helix" DNA-binding domain | Actin-like ATPase domain | 7 | 6 |  |
P-loop containing nucleoside triphosphate hydrolases | Actin-like ATPase domain | 7 | 6 |  |
Leukotriene A4 hydrolase N-terminal domain | Metalloproteases ("zincins"), catalytic domain | 7 | 3 |  |
TAZ domain | RING/U-box | 7 | 3 |  |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 7 | 4 |  |
Carbamate kinase-like | ALDH-like | 7 | 1 |  |
GAF domain-like | Homodimeric domain of signal transducing histidine kinase | 7 | 4 |  |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 7 | 2 |  |
NAD(P)-binding Rossmann-fold domains | Galactose-binding domain-like | 7 | 2 |  |
Voltage-gated potassium channels | TrkA C-terminal domain-like | 7 | 1 |  |
RING/U-box | RNA-binding domain, RBD | 7 | 1 |  |
CO dehydrogenase flavoprotein C-terminal domain-like | CO dehydrogenase molybdoprotein N-domain-like | 7 | 2 |  |
POZ domain | TAZ domain | 7 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | UBA-like | 7 | 5 |  |
PurM N-terminal domain-like | PurM C-terminal domain-like | 7 | 4 |  |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 7 | 3 |  |
Ubiquitin-like | BAG domain | 7 | 3 |  |
CO dehydrogenase ISP C-domain like | FAD-binding/transporter-associated domain-like | 7 | 2 |  |
(Phosphotyrosine protein) phosphatases II | DNA ligase/mRNA capping enzyme, catalytic domain | 7 | 4 |  |
Glycoside hydrolase/deacetylase | Galactose mutarotase-like | 7 | 4 |  |
PAZ domain | RNase III domain-like | 7 | 5 |  |
Thioredoxin-like | TPR-like | 7 | 4 |  |
CO dehydrogenase molybdoprotein N-domain-like | Molybdenum cofactor-binding domain | 7 | 2 |  |
EF-hand | Mitochondrial carrier | 7 | 2 |  |
F-box domain | HCP-like | 7 | 3 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 7 | 3 |  |
Thioredoxin-like | Cysteine-rich domain | 6 | 2 |  |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 6 | 3 |  |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 6 | 2 |  |
ACT-like | Formyltransferase | 6 | 1 |  |
Peptidase/esterase 'gauge' domain | alpha/beta-Hydrolases | 6 | 2 |  |
Voltage-gated potassium channels | Voltage-gated potassium channels | 6 | 3 |  |
Carbamate kinase-like | NAD(P)-binding Rossmann-fold domains | 6 | 2 |  |
CBS-domain pair | CAD & PB1 domains | 6 | 2 |  |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 6 | 2 |  |
BAR/IMD domain-like | PH domain-like | 6 | 4 |  |
SAP domain | FYVE/PHD zinc finger | 6 | 2 |  |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 6 | 4 |  |
PH domain-like | ArfGap/RecO-like zinc finger | 6 | 4 |  |
Cdc48 domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 6 | 2 |  |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 6 | 2 |  |
Trypsin-like serine proteases | Trypsin-like serine proteases | 6 | 5 |  |
GroEL apical domain-like | SAICAR synthase-like | 6 | 3 |  |
2Fe-2S ferredoxin-like | CO dehydrogenase ISP C-domain like | 6 | 1 |  |
Ubiquitin-like | Cap-Gly domain | 6 | 2 |  |
"Winged helix" DNA-binding domain | E2F-DP heterodimerization region | 6 | 2 |  |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 6 | 3 |  |
Retrovirus zinc finger-like domains | RING/U-box | 6 | 1 |  |
(Phosphotyrosine protein) phosphatases II | Nucleic acid-binding proteins | 6 | 3 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 6 | 4 |  |
BAR/IMD domain-like | ArfGap/RecO-like zinc finger | 6 | 4 |  |
LEA14-like | LEA14-like | 6 | 2 |  |
ADC-like | P-loop containing nucleoside triphosphate hydrolases | 6 | 2 |  |
Creatinase/aminopeptidase | "Winged helix" DNA-binding domain | 6 | 3 |  |
(Trans)glycosidases | (Trans)glycosidases | 6 | 3 |  |
(Trans)glycosidases | Protein kinase-like (PK-like) | 6 | 3 |  |
FAD/NAD(P)-binding domain | EF-hand | 6 | 2 |  |
FYVE/PHD zinc finger | Plus3-like | 6 | 3 |  |
Toll/Interleukin receptor TIR domain | Actin-like ATPase domain | 6 | 5 |  |
Translational machinery components | L30e-like | 6 | 3 |  |
ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 6 | 4 |  |
SMAD/FHA domain | P-loop containing nucleoside triphosphate hydrolases | 6 | 1 |  |
2Fe-2S ferredoxin-like | CO dehydrogenase molybdoprotein N-domain-like | 6 | 1 |  |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase | 6 | 2 |  |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 6 | 3 |  |
"Winged helix" DNA-binding domain | RNA-binding domain, RBD | 6 | 3 |  |
Ribonuclease H-like | HRDC-like | 6 | 2 |  |
UDP-Glycosyltransferase/glycogen phosphorylase | UDP-Glycosyltransferase/glycogen phosphorylase | 6 | 2 |  |
MOSC N-terminal domain-like | PK beta-barrel domain-like | 6 | 1 |  |
GST C-terminal domain-like | eEF-1beta-like | 6 | 3 |  |
Carbamate kinase-like | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 6 | 2 |  |
4Fe-4S ferredoxins | P-loop containing nucleoside triphosphate hydrolases | 6 | 1 |  |
PH domain-like | RCC1/BLIP-II | 6 | 1 |  |
Plant lectins/antimicrobial peptides | Lysozyme-like | 6 | 2 |  |
TPR-like | RING/U-box | 6 | 3 |  |
Cysteine proteinases | Sec-C motif | 6 | 1 |  |
POZ domain | TPR-like | 6 | 4 |  |
2Fe-2S ferredoxin-like | FAD-binding/transporter-associated domain-like | 6 | 1 |  |
RING/U-box | PUA domain-like | 6 | 3 |  |
Tetrahydrobiopterin biosynthesis enzymes-like | Tetrahydrobiopterin biosynthesis enzymes-like | 6 | 2 |  |
SWIB/MDM2 domain | Plus3-like | 6 | 3 |  |
Ubiquitin-like | Zn-binding ribosomal proteins | 6 | 1 |  |
Oxidoreductase molybdopterin-binding domain | E set domains | 6 | 3 |  |
ARM repeat | Clathrin adaptor appendage domain | 6 | 4 |  |
Ubiquitin-like | Protein kinase-like (PK-like) | 6 | 1 |  |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 6 | 4 |  |
2Fe-2S ferredoxin-like | CO dehydrogenase flavoprotein C-terminal domain-like | 6 | 1 |  |
ACT-like | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 6 | 2 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | vWA-like | 6 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 6 | 1 |  |
PriA/YqbF domain | GINS helical bundle-like | 6 | 2 |  |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 6 | 2 |  |
2Fe-2S ferredoxin-like | Molybdenum cofactor-binding domain | 6 | 1 |  |
Translation proteins | ThrRS/AlaRS common domain | 6 | 2 |  |
Actin depolymerizing proteins | VHP, Villin headpiece domain | 6 | 2 |  |
FYVE/PHD zinc finger | Homeodomain-like | 6 | 2 |  |
Acyl-CoA N-acyltransferases (Nat) | Acyl-CoA N-acyltransferases (Nat) | 5 | 2 |  |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 5 | 2 |  |
GST C-terminal domain-like | eEF1-gamma domain | 5 | 1 |  |
TPR-like | "Winged helix" DNA-binding domain | 5 | 2 |  |
ArfGap/RecO-like zinc finger | Ankyrin repeat | 5 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | Epsilon subunit of F1F0-ATP synthase N-terminal domain | 5 | 2 |  |
CRAL/TRIO N-terminal domain | Supernatant protein factor (SPF), C-terminal domain | 5 | 2 |  |
Voltage-gated potassium channels | Ankyrin repeat | 5 | 1 |  |
Protein kinase-like (PK-like) | KA1-like | 5 | 1 |  |
TRAF domain-like | TRAF domain-like | 5 | 4 |  |
Class I glutamine amidotransferase-like | Class I glutamine amidotransferase-like | 5 | 2 |  |
BEACH domain | WD40 repeat-like | 5 | 4 |  |
cAMP-binding domain-like | Ankyrin repeat | 5 | 1 |  |
SMAD/FHA domain | PP2C-like | 5 | 1 |  |
Metallo-hydrolase/oxidoreductase | ATP-dependent DNA ligase DNA-binding domain | 5 | 3 |  |
F1F0 ATP synthase subunit C | F1F0 ATP synthase subunit C | 5 | 1 |  |
Metallo-dependent hydrolases | Glutamine synthetase/guanido kinase | 5 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 5 | 3 |  |
HCP-like | HIT/MYND zinc finger-like | 5 | 2 |  |
BAR/IMD domain-like | Ankyrin repeat | 5 | 3 |  |
UBC-like | UBA-like | 5 | 1 |  |
Metallo-dependent hydrolases | Glutamine synthetase, N-terminal domain | 5 | 1 |  |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 5 | 3 |  |
Thioredoxin-like | eEF1-gamma domain | 5 | 1 |  |
F-box domain | Actin-like ATPase domain | 5 | 1 |  |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 5 | 1 |  |
Homeodomain-like | P-loop containing nucleoside triphosphate hydrolases | 5 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | Macro domain-like | 5 | 3 |  |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 5 | 3 |  |
RING/U-box | UBA-like | 5 | 2 |  |
Domain of poly(ADP-ribose) polymerase | ADP-ribosylation | 5 | 4 |  |
Adenine nucleotide alpha hydrolases-like | YjgF-like | 5 | 1 |  |
ARM repeat | Tudor/PWWP/MBT | 5 | 4 |  |
PYP-like sensor domain (PAS domain) | GAF domain-like | 5 | 1 |  |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 5 | 4 |  |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | DNA breaking-rejoining enzymes | 5 | 2 |  |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 5 | 1 |  |
GAF domain-like | CheY-like | 5 | 3 |  |
PH domain-like | Ankyrin repeat | 5 | 3 |  |
UROD/MetE-like | UROD/MetE-like | 5 | 2 |  |
Class II aaRS and biotin synthetases | Translation proteins | 5 | 1 |  |
GAF domain-like | GAF domain-like | 5 | 1 |  |
Protein kinase-like (PK-like) | P-loop containing nucleoside triphosphate hydrolases | 5 | 5 |  |
FYVE/PHD zinc finger | SWIB/MDM2 domain | 5 | 2 |  |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 5 | 1 |  |
Ricin B-like lectins | Glycosyl hydrolase domain | 5 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 5 | 2 |  |
Metallo-hydrolase/oxidoreductase | DNA ligase/mRNA capping enzyme, catalytic domain | 5 | 3 |  |
PYP-like sensor domain (PAS domain) | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 5 | 1 |  |
Kelch motif | Kelch motif | 5 | 3 |  |
SWIB/MDM2 domain | SWIB/MDM2 domain | 5 | 2 |  |
alpha-D-mannose-specific plant lectins | alpha-D-mannose-specific plant lectins | 5 | 3 |  |
SET domain | TPR-like | 5 | 2 |  |
YjgF-like | YjgF-like | 5 | 1 |  |
RBP11-like subunits of RNA polymerase | Insert subdomain of RNA polymerase alpha subunit | 5 | 3 |  |
Sec63 N-terminal domain-like | Sec63 N-terminal domain-like | 5 | 2 |  |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | Epsilon subunit of F1F0-ATP synthase N-terminal domain | 5 | 2 |  |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 5 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Phosphoglycerate mutase-like | 5 | 2 |  |
PLC-like phosphodiesterases | PLC-like phosphodiesterases | 5 | 3 |  |
PAZ domain | dsRNA-binding domain-like | 5 | 3 |  |
Chaperone J-domain | 4Fe-4S ferredoxins | 5 | 3 |  |
RNA-binding domain, RBD | PWI domain | 5 | 2 |  |
Ribulose-phoshate binding barrel | Ribulose-phoshate binding barrel | 5 | 2 |  |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 5 | 1 |  |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 5 | 2 |  |
CCCH zinc finger | Eukaryotic type KH-domain (KH-domain type I) | 5 | 3 |  |
Nucleic acid-binding proteins | Eukaryotic type KH-domain (KH-domain type I) | 5 | 3 |  |
CRAL/TRIO domain | Supernatant protein factor (SPF), C-terminal domain | 5 | 2 |  |
CCCH zinc finger | RING/U-box | 5 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Tropomyosin | 5 | 4 |  |
Acyl-CoA dehydrogenase C-terminal domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 5 | 2 |  |
Ubiquitin-like | Homeodomain-like | 5 | 1 |  |
Thioredoxin-like | "Winged helix" DNA-binding domain | 4 | 1 |  |
alpha/beta-Hydrolases | alpha/beta-Hydrolases | 4 | 3 |  |
Chaperone J-domain | CSL zinc finger | 4 | 2 |  |
FYVE/PHD zinc finger | Clavaminate synthase-like | 4 | 2 |  |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 4 | 2 |  |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 4 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Pre-protein crosslinking domain of SecA | 4 | 4 |  |
WD40 repeat-like | DNase I-like | 4 | 2 |  |
Clathrin heavy-chain terminal domain | ARM repeat | 4 | 1 |  |
E set domains | RNA-binding domain, RBD | 4 | 1 |  |
SNARE fusion complex | SNARE fusion complex | 4 | 2 |  |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 4 | 1 |  |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 4 | 2 |  |
ARM repeat | Subdomain of clathrin and coatomer appendage domain | 4 | 3 |  |
NAD(P)-binding Rossmann-fold domains | Glutamyl tRNA-reductase dimerization domain | 4 | 2 |  |
Ubiquitin-like | Hect, E3 ligase catalytic domain | 4 | 2 |  |
Hemopexin-like domain | Hemopexin-like domain | 4 | 1 |  |
Dimeric alpha+beta barrel | Dimeric alpha+beta barrel | 4 | 1 |  |
Arp2/3 complex subunits | Arp2/3 complex subunits | 4 | 1 |  |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | Zinc-binding domain of translation initiation factor 2 beta | 4 | 2 |  |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 4 | 2 |  |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 4 | 2 |  |
UBA-like | Hect, E3 ligase catalytic domain | 4 | 2 |  |
Protein kinase-like (PK-like) | PP2C-like | 4 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | F-box domain | 4 | 4 |  |
P-loop containing nucleoside triphosphate hydrolases | Prokaryotic type KH domain (KH-domain type II) | 4 | 2 |  |
Glutamyl tRNA-reductase catalytic, N-terminal domain | Glutamyl tRNA-reductase dimerization domain | 4 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 4 | 2 |  |
tRNA-binding arm | Class II aaRS and biotin synthetases | 4 | 2 |  |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 4 | 3 |  |
F-box domain | HIT/MYND zinc finger-like | 4 | 1 |  |
ARM repeat | TPR-like | 4 | 3 |  |
Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 4 | 1 |  |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain II | 4 | 2 |  |
SBT domain | Ankyrin repeat | 4 | 2 |  |
PH domain-like | WD40 repeat-like | 4 | 3 |  |
TPR-like | HSP20-like chaperones | 4 | 2 |  |
USP8 N-terminal domain-like | JAB1/MPN domain | 4 | 2 |  |
PH domain-like | Phospholipase D/nuclease | 4 | 2 |  |
Putative DNA-binding domain | Putative DNA-binding domain | 4 | 2 |  |
Putative isomerase YbhE | WD40 repeat-like | 4 | 3 |  |
MIT domain | P-loop containing nucleoside triphosphate hydrolases | 4 | 1 |  |
E set domains | E set domains | 4 | 2 |  |
YrdC/RibB | RibA-like | 4 | 2 |  |
Protein kinase-like (PK-like) | PH domain-like | 4 | 2 |  |
vWA-like | Cysteine-rich domain | 4 | 1 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | Epsilon subunit of F1F0-ATP synthase N-terminal domain | 4 | 1 |  |
FYVE/PHD zinc finger | GYF domain | 4 | 2 |  |
Chitinase insertion domain | Protein kinase-like (PK-like) | 4 | 2 |  |
ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 4 | 2 |  |
PRTase-like | PRTase-like | 4 | 2 |  |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 4 | 2 |  |
FYVE/PHD zinc finger | GroEL apical domain-like | 4 | 2 |  |
BRCT domain | FYVE/PHD zinc finger | 4 | 3 |  |
PH domain-like | BEACH domain | 4 | 3 |  |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 4 | 2 |  |
WW domain | FF domain | 4 | 3 |  |
alpha-D-mannose-specific plant lectins | Hairpin loop containing domain-like | 4 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Bromodomain | 4 | 2 |  |
BRCT domain | RING/U-box | 4 | 2 |  |
WW domain | P-loop containing nucleoside triphosphate hydrolases | 4 | 1 |  |
Activating enzymes of the ubiquitin-like proteins | Activating enzymes of the ubiquitin-like proteins | 4 | 3 |  |
FF domain | FF domain | 4 | 3 |  |
Globin-like | Globin-like | 4 | 1 |  |
CCCH zinc finger | HIT-like | 4 | 1 |  |
Glutamyl tRNA-reductase catalytic, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 4 | 2 |  |
PRTase-like | Ribulose-phoshate binding barrel | 4 | 1 |  |
NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 4 | 1 |  |
Formate/glycerate dehydrogenase catalytic domain-like | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 4 | 1 |  |
Hairpin loop containing domain-like | Protein kinase-like (PK-like) | 4 | 2 |  |
Cyclophilin-like | TPR-like | 4 | 1 |  |
PH domain-like | GTPase activation domain, GAP | 4 | 1 |  |
ARID-like | Clavaminate synthase-like | 4 | 2 |  |
(Phosphotyrosine protein) phosphatases II | NAD kinase/diacylglycerol kinase-like | 4 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | Quinoprotein alcohol dehydrogenase-like | 4 | 3 |  |
Starch-binding domain-like | Phosphoglycerate mutase-like | 4 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 4 | 3 |  |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 4 | 2 |  |
Clathrin adaptor appendage domain | Subdomain of clathrin and coatomer appendage domain | 4 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | RNA-binding domain, RBD | 4 | 4 |  |
S15/NS1 RNA-binding domain | Class II aaRS and biotin synthetases | 4 | 2 |  |
ARM repeat | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 4 |  |
PA domain | Transferrin receptor-like dimerisation domain | 4 | 1 |  |
Kelch motif | Metallo-dependent phosphatases | 4 | 2 |  |
PH domain-like | ARM repeat | 4 | 3 |  |
FYVE/PHD zinc finger | Ankyrin repeat | 4 | 1 |  |
Zn-dependent exopeptidases | Transferrin receptor-like dimerisation domain | 4 | 1 |  |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 4 | 3 |  |
FYVE/PHD zinc finger | Transducin (alpha subunit), insertion domain | 4 | 2 |  |
Cysteine proteinases | Ubiquitin-like | 4 | 2 |  |
Quinoprotein alcohol dehydrogenase-like | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 4 | 3 |  |
ARM repeat | UBA-like | 4 | 2 |  |
PurM N-terminal domain-like | Class I glutamine amidotransferase-like | 4 | 2 |  |
FYVE/PHD zinc finger | SAICAR synthase-like | 4 | 2 |  |
PurM C-terminal domain-like | Class I glutamine amidotransferase-like | 4 | 2 |  |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 4 | 1 |  |
WD40 repeat-like | F-box domain | 4 | 3 |  |
Starch-binding domain-like | P-loop containing nucleoside triphosphate hydrolases | 4 | 1 |  |
PUG domain-like | Ubiquitin-like | 4 | 3 |  |
Heat shock protein 70kD (HSP70), C-terminal subdomain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 3 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | YVTN repeat-like/Quinoprotein amine dehydrogenase | 3 | 3 |  |
Cytidine deaminase-like | Dihydrofolate reductase-like | 3 | 2 |  |
Amidase signature (AS) enzymes | TPR-like | 3 | 1 |  |
"Winged helix" DNA-binding domain | Protein kinase-like (PK-like) | 3 | 2 |  |
Molybdenum cofactor biosynthesis proteins | MoeA C-terminal domain-like | 3 | 3 |  |
WGR domain-like | ADP-ribosylation | 3 | 3 |  |
Fe-S cluster assembly (FSCA) domain-like | Fe-S cluster assembly (FSCA) domain-like | 3 | 1 |  |
BRCA2 helical domain | BRCA2 tower domain | 3 | 3 |  |
beta-Galactosidase/glucuronidase domain | (Trans)glycosidases | 3 | 2 |  |
L domain-like | Elongation factor Ts (EF-Ts), dimerisation domain | 3 | 3 |  |
BRCT domain | Lesion bypass DNA polymerase (Y-family), little finger domain | 3 | 1 |  |
E set domains | Cytochrome b5-like heme/steroid binding domain | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | RecA protein, C-terminal domain | 3 | 2 |  |
DNase I-like | DNase I-like | 3 | 2 |  |
PreATP-grasp domain | PreATP-grasp domain | 3 | 3 |  |
Chaperone J-domain | Sec63 N-terminal domain-like | 3 | 1 |  |
Cytochrome f, large domain | Rudiment single hybrid motif | 3 | 2 |  |
Voltage-gated potassium channels | Glycosyl hydrolase domain | 3 | 3 |  |
Calponin-homology domain, CH-domain | EB1 dimerisation domain-like | 3 | 2 |  |
AN1-like Zinc finger | AN1-like Zinc finger | 3 | 2 |  |
PapD-like | Ankyrin repeat | 3 | 3 |  |
Oxidoreductase molybdopterin-binding domain | Cytochrome b5-like heme/steroid binding domain | 3 | 2 |  |
Ribonuclease PH domain 2-like | Nucleic acid-binding proteins | 3 | 2 |  |
Cyclophilin-like | RNA-binding domain, RBD | 3 | 1 |  |
Chaperone J-domain | E set domains | 3 | 1 |  |
HAD-like | Thioredoxin-like | 3 | 1 |  |
Undecaprenyl diphosphate synthase | Undecaprenyl diphosphate synthase | 3 | 1 |  |
beta and beta-prime subunits of DNA dependent RNA-polymerase | beta and beta-prime subunits of DNA dependent RNA-polymerase | 3 | 2 |  |
"Winged helix" DNA-binding domain | Elongation factor Ts (EF-Ts), dimerisation domain | 3 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | DNA/RNA polymerases | 3 | 3 |  |
Translational machinery components | Insert subdomain of RNA polymerase alpha subunit | 3 | 2 |  |
Tropomyosin | Apolipoprotein A-I | 3 | 1 |  |
WGR domain-like | Domain of poly(ADP-ribose) polymerase | 3 | 3 |  |
DNA-binding domain | DNA-binding pseudobarrel domain | 3 | 3 |  |
CorA soluble domain-like | Magnesium transport protein CorA, transmembrane region | 3 | 2 |  |
Dom34/Pelota N-terminal domain-like | L30e-like | 3 | 1 |  |
F-box domain | Protein kinase-like (PK-like) | 3 | 2 |  |
HAD-like | Riboflavin kinase-like | 3 | 1 |  |
Nucleic acid-binding proteins | eIF2alpha middle domain-like | 3 | 1 |  |
FGAM synthase PurL, linker domain | PurM C-terminal domain-like | 3 | 1 |  |
Heme oxygenase-like | HAD-like | 3 | 2 |  |
Eukaryotic type KH-domain (KH-domain type I) | LigT-like | 3 | 2 |  |
BRCT domain | DNA/RNA polymerases | 3 | 1 |  |
RNA-binding domain, RBD | DNase I-like | 3 | 2 |  |
Transcription factor IIA (TFIIA), alpha-helical domain | Transcription factor IIA (TFIIA), beta-barrel domain | 3 | 2 |  |
Adenine nucleotide alpha hydrolases-like | Argininosuccinate synthetase, C-terminal domain | 3 | 1 |  |
Translational machinery components | RBP11-like subunits of RNA polymerase | 3 | 2 |  |
Protein kinase-like (PK-like) | (Phosphotyrosine protein) phosphatases II | 3 | 1 |  |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 |  |
SufE/NifU | BolA-like | 3 | 1 |  |
Ribonuclease PH domain 2-like | Ribonuclease PH domain 2-like | 3 | 2 |  |
HMA, heavy metal-associated domain | "Winged helix" DNA-binding domain | 3 | 2 |  |
Cation efflux protein cytoplasmic domain-like | Cation efflux protein cytoplasmic domain-like | 3 | 2 |  |
RNI-like | ARM repeat | 3 | 1 |  |
Actin-crosslinking proteins | Actin-crosslinking proteins | 3 | 1 |  |
HisI-like | all-alpha NTP pyrophosphatases | 3 | 2 |  |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 3 | 3 |  |
PurM C-terminal domain-like | PurM C-terminal domain-like | 3 | 1 |  |
Concanavalin A-like lectins/glucanases | WD40 repeat-like | 3 | 2 |  |
Elongation factor Ts (EF-Ts), dimerisation domain | Elongation factor Ts (EF-Ts), dimerisation domain | 3 | 3 |  |
Dom34/Pelota N-terminal domain-like | Translational machinery components | 3 | 1 |  |
E set domains | Riboflavin synthase domain-like | 3 | 2 |  |
LysM domain | LysM domain | 3 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | Riboflavin synthase domain-like | 3 | 2 |  |
Ribosomal protein S5 domain 2-like | Nucleic acid-binding proteins | 3 | 2 |  |
DEK C-terminal domain | ssDNA-binding transcriptional regulator domain | 3 | 1 |  |
PurS-like | FGAM synthase PurL, linker domain | 3 | 1 |  |
Phage tail proteins | Phage tail proteins | 3 | 3 |  |
P-loop containing nucleoside triphosphate hydrolases | Elongation factor Ts (EF-Ts), dimerisation domain | 3 | 3 |  |
Ribonuclease H-like | Ribonuclease H-like | 3 | 2 |  |
Metallo-hydrolase/oxidoreductase | Nucleic acid-binding proteins | 3 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Hypothetical protein YjiA, C-terminal domain | 3 | 1 |  |
PurM N-terminal domain-like | PurM N-terminal domain-like | 3 | 1 |  |
PUA domain-like | Ribosomal protein S5 domain 2-like | 3 | 2 |  |
Concanavalin A-like lectins/glucanases | BEACH domain | 3 | 2 |  |
PurS-like | PurM C-terminal domain-like | 3 | 1 |  |
PreATP-grasp domain | Single hybrid motif | 3 | 3 |  |
Bacterial photosystem II reaction centre, L and M subunits | Photosystem II antenna protein-like | 3 | 1 |  |
Second domain of FERM | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 |  |
Bactericidal permeability-increasing protein, BPI | Bactericidal permeability-increasing protein, BPI | 3 | 1 |  |
Thioredoxin-like | Ubiquitin-like | 3 | 1 |  |
Cysteine-rich domain | NAD kinase/diacylglycerol kinase-like | 3 | 2 |  |
Tricorn protease N-terminal domain | DPP6 N-terminal domain-like | 3 | 1 |  |
Ubiquitin-like | TPR-like | 3 | 1 |  |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 3 | 1 |  |
Saposin | Saposin | 3 | 2 |  |
UBA-like | XPC-binding domain | 3 | 2 |  |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 3 | 1 |  |
Toll/Interleukin receptor TIR domain | UDP-Glycosyltransferase/glycogen phosphorylase | 3 | 3 |  |
PurS-like | Class I glutamine amidotransferase-like | 3 | 1 |  |
Nucleic acid-binding proteins | eIF-2-alpha, C-terminal domain | 3 | 1 |  |
Scorpion toxin-like | Scorpion toxin-like | 3 | 2 |  |
HLH, helix-loop-helix DNA-binding domain | ACT-like | 3 | 2 |  |
Ribosomal protein L6 | Ribosomal protein L6 | 3 | 1 |  |
Chaperone J-domain | RNA-binding domain, RBD | 3 | 2 |  |
HAND domain of the nucleosome remodeling ATPase ISWI | Homeodomain-like | 3 | 2 |  |
Osmotin, thaumatin-like protein | Protein kinase-like (PK-like) | 3 | 2 |  |
Nucleotidylyl transferase | Ribosomal protein L25-like | 3 | 2 |  |
Ribosomal protein S5 domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 3 | 2 |  |
Histone-fold | ARM repeat | 3 | 2 |  |
PUA domain-like | alpha/beta knot | 3 | 1 |  |
Class II aaRS and biotin synthetases | HD-domain/PDEase-like | 3 | 3 |  |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Nucleic acid-binding proteins | 3 | 2 |  |
Oxidoreductase molybdopterin-binding domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 3 | 2 |  |
PLP-dependent transferases | Ornithine decarboxylase C-terminal domain | 3 | 1 |  |
Chaperone J-domain | Thioredoxin-like | 3 | 2 |  |
Alpha-L RNA-binding motif | Pseudouridine synthase | 3 | 1 |  |
Osmotin, thaumatin-like protein | alpha-D-mannose-specific plant lectins | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | vWA-like | 3 | 2 |  |
GroEL-intermediate domain like | GroEL-intermediate domain like | 3 | 2 |  |
Pre-protein crosslinking domain of SecA | Helical scaffold and wing domains of SecA | 3 | 3 |  |
MoeA N-terminal region -like | Molybdenum cofactor biosynthesis proteins | 3 | 3 |  |
Formiminotransferase domain of formiminotransferase-cyclodeaminase. | Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 3 | 1 |  |
Rap30/74 interaction domains | "Winged helix" DNA-binding domain | 3 | 2 |  |
HAD-like | Glycerol-3-phosphate (1)-acyltransferase | 3 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | HAD-like | 3 | 1 |  |
Flavoproteins | Protein kinase-like (PK-like) | 3 | 1 |  |
PheT/TilS domain | Class II aaRS and biotin synthetases | 3 | 1 |  |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 3 | 2 |  |
HAD-like | NHL repeat | 3 | 1 |  |
Translation proteins | Translation proteins | 3 | 1 |  |
eIF2alpha middle domain-like | eIF-2-alpha, C-terminal domain | 3 | 1 |  |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 3 | 2 |  |
WWE domain | ADP-ribosylation | 3 | 2 |  |
PAH2 domain | F-box domain | 3 | 1 |  |
Outer arm dynein light chain 1 | L domain-like | 3 | 3 |  |
PRP4-like | WD40 repeat-like | 3 | 2 |  |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 3 | 2 |  |
Tudor/PWWP/MBT | RNA-binding domain, RBD | 3 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Helical scaffold and wing domains of SecA | 3 | 3 |  |
Putative DNA-binding domain | PheT/TilS domain | 3 | 1 |  |
PurS-like | PurM N-terminal domain-like | 3 | 1 |  |
Rudiment single hybrid motif | Single hybrid motif | 3 | 3 |  |
WD40 repeat-like | DPP6 N-terminal domain-like | 3 | 2 |  |
(Phosphotyrosine protein) phosphatases II | Actin depolymerizing proteins | 3 | 2 |  |
Clavaminate synthase-like | Clavaminate synthase-like | 3 | 1 |  |
HAD-like | NTF2-like | 3 | 1 |  |
MoeA N-terminal region -like | MoeA C-terminal domain-like | 3 | 3 |  |
Cytochrome b5-like heme/steroid binding domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 3 | 2 |  |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | Translational machinery components | 3 | 2 |  |
Ribosomal proteins S24e, L23 and L15e | Nucleic acid-binding proteins | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | HAND domain of the nucleosome remodeling ATPase ISWI | 3 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | UDP-Glycosyltransferase/glycogen phosphorylase | 3 | 3 |  |
L domain-like | UDP-Glycosyltransferase/glycogen phosphorylase | 3 | 3 |  |
Ribonuclease PH domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 3 | 2 |  |
Nucleic acid-binding proteins | BRCA2 tower domain | 3 | 3 |  |
FGAM synthase PurL, linker domain | PurM N-terminal domain-like | 3 | 1 |  |
TPR-like | PUA domain-like | 3 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 3 | 3 |  |
PH domain-like | HMG-box | 3 | 1 |  |
Cullin repeat-like | Cullin repeat-like | 3 | 3 |  |
Thioredoxin-like | NHL repeat | 3 | 1 |  |
Concanavalin A-like lectins/glucanases | PH domain-like | 3 | 2 |  |
E set domains | Ferredoxin reductase-like, C-terminal NADP-linked domain | 3 | 2 |  |
POZ domain | RNI-like | 3 | 2 |  |
DUSP-like | Ubiquitin-like | 3 | 1 |  |
Macro domain-like | CRAL/TRIO domain | 3 | 1 |  |
Oxidoreductase molybdopterin-binding domain | Riboflavin synthase domain-like | 3 | 2 |  |
BRCA2 helical domain | Nucleic acid-binding proteins | 3 | 3 |  |
Second domain of FERM | PH domain-like | 3 | 2 |  |
Ribosomal L27 protein-like | Nucleic acid-binding proteins | 3 | 2 |  |
beta-Galactosidase/glucuronidase domain | beta-Galactosidase/glucuronidase domain | 3 | 2 |  |
Ubiquitin-like | XPC-binding domain | 3 | 2 |  |
Cystatin/monellin | Cystatin/monellin | 3 | 3 |  |
FGAM synthase PurL, linker domain | Class I glutamine amidotransferase-like | 3 | 1 |  |
HIT-like | HIT-like | 3 | 2 |  |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | L30e-like | 3 | 2 |  |
DNA polymerase beta, N-terminal domain-like | PsbU/PolX domain-like | 2 | 1 |  |
Phage tail proteins | Phage fibre proteins | 2 | 2 |  |
PDZ domain-like | (Phosphotyrosine protein) phosphatases II | 2 | 2 |  |
Formate/glycerate dehydrogenase catalytic domain-like | Formate/glycerate dehydrogenase catalytic domain-like | 2 | 1 |  |
Heme-dependent peroxidases | Heme-dependent peroxidases | 2 | 1 |  |
NAD(P)-binding Rossmann-fold domains | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 2 | 1 |  |
Galactose oxidase, central domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Cytochrome f, large domain | Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor | 2 | 1 |  |
SWIB/MDM2 domain | GYF domain | 2 | 1 |  |
Barwin-like endoglucanases | Protein kinase-like (PK-like) | 2 | 1 |  |
Clavaminate synthase-like | RING/U-box | 2 | 2 |  |
Cytidine deaminase-like | YbiA-like | 2 | 1 |  |
EF-hand | Calponin-homology domain, CH-domain | 2 | 2 |  |
Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 2 | 2 |  |
Urease, gamma-subunit | Urease, beta-subunit | 2 | 2 |  |
Chelatase | Chlorophyll a-b binding protein | 2 | 1 |  |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 2 | 1 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleic acid-binding proteins | 2 | 1 |  |
BSD domain-like | BSD domain-like | 2 | 1 |  |
Cytochrome P450 | Cytochrome P450 | 2 | 1 |  |
FAD/NAD(P)-binding domain | SMAD/FHA domain | 2 | 1 |  |
DHS-like NAD/FAD-binding domain | alpha/beta-Hydrolases | 2 | 1 |  |
F-box domain | SMI1/KNR4-like | 2 | 2 |  |
WD40 repeat-like | SNARE fusion complex | 2 | 2 |  |
Urease, gamma-subunit | Metallo-dependent hydrolases | 2 | 2 |  |
FYVE/PHD zinc finger | TPR-like | 2 | 1 |  |
Lipoxigenase | Class II aaRS and biotin synthetases | 2 | 1 |  |
Tricorn protease domain 2 | Quinoprotein alcohol dehydrogenase-like | 2 | 2 |  |
Ubiquitin-like | L domain-like | 2 | 2 |  |
Voltage-gated potassium channels | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
HMA, heavy metal-associated domain | L domain-like | 2 | 1 |  |
Radical SAM enzymes | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 |  |
SAND domain-like | SET domain | 2 | 1 |  |
BRCT domain | PsbU/PolX domain-like | 2 | 1 |  |
L domain-like | Leucine zipper domain | 2 | 1 |  |
SAP domain | RNA-binding domain, RBD | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | NAD(P)-binding Rossmann-fold domains | 2 | 2 |  |
Clavaminate synthase-like | beta-beta-alpha zinc fingers | 2 | 2 |  |
Tudor/PWWP/MBT | SAND domain-like | 2 | 1 |  |
Nqo1 middle domain-like | Nqo1C-terminal domain-like | 2 | 1 |  |
BRCT domain | DNA polymerase beta, N-terminal domain-like | 2 | 1 |  |
Phage tail proteins | gp5 N-terminal domain-like | 2 | 2 |  |
Calcyclin-binding protein-like | HSP20-like chaperones | 2 | 1 |  |
Macro domain-like | Zn-dependent exopeptidases | 2 | 1 |  |
F-box domain | Acid proteases | 2 | 1 |  |
Trimeric LpxA-like enzymes | Trimeric LpxA-like enzymes | 2 | 2 |  |
Acetyl-CoA synthetase-like | Trimeric LpxA-like enzymes | 2 | 2 |  |
Pentein | Pentein | 2 | 1 |  |
HMA, heavy metal-associated domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Acetyl-CoA synthetase-like | ACP-like | 2 | 2 |  |
beta-sandwich domain of Sec23/24 | Leucine zipper domain | 2 | 1 |  |
Ribosomal proteins S24e, L23 and L15e | YWTD domain | 2 | 1 |  |
TPR-like | RNI-like | 2 | 2 |  |
Fe-S cluster assembly (FSCA) domain-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
BRCT domain | Nucleotidyltransferase | 2 | 1 |  |
Aldolase | NAD(P)-binding Rossmann-fold domains | 2 | 1 |  |
PLP-dependent transferases | PLP-dependent transferases | 2 | 2 |  |
CarD-like | TRCF domain-like | 2 | 1 |  |
BRCT domain | post-AAA+ oligomerization domain-like | 2 | 1 |  |
Urease, beta-subunit | Metallo-dependent hydrolases | 2 | 2 |  |
Nqo1 FMN-binding domain-like | Nqo1C-terminal domain-like | 2 | 1 |  |
Cullin repeat-like | POZ domain | 2 | 1 |  |
Nucleic acid-binding proteins | S15/NS1 RNA-binding domain | 2 | 1 |  |
(Phosphotyrosine protein) phosphatases II | E set domains | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | D-aminoacid aminotransferase-like PLP-dependent enzymes | 2 | 2 |  |
UBA-like | PUG domain-like | 2 | 2 |  |
L domain-like | UBA-like | 2 | 2 |  |
Cytochrome c | Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor | 2 | 1 |  |
Urease, beta-subunit | Composite domain of metallo-dependent hydrolases | 2 | 2 |  |
Pseudouridine synthase | Pseudouridine synthase | 2 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | alpha/beta-Hydrolases | 2 | 1 |  |
RING/U-box | Cyclophilin-like | 2 | 1 |  |
Single hybrid motif | Single hybrid motif | 2 | 1 |  |
Aminopeptidase/glucanase lid domain | Zn-dependent exopeptidases | 2 | 1 |  |
ARID-like | HSP20-like chaperones | 2 | 1 |  |
CAD & PB1 domains | RING/U-box | 2 | 1 |  |
YVTN repeat-like/Quinoprotein amine dehydrogenase | WD40 repeat-like | 2 | 2 |  |
Nucleic acid-binding proteins | BRCT domain | 2 | 1 |  |
C-terminal, gelsolin-like domain of Sec23/24 | VHP, Villin headpiece domain | 2 | 1 |  |
TPR-like | Metallo-dependent phosphatases | 2 | 1 |  |
FMN-linked oxidoreductases | Alpha subunit of glutamate synthase, C-terminal domain | 2 | 2 |  |
HydB/Nqo4-like | 4Fe-4S ferredoxins | 2 | 2 |  |
FAD/NAD(P)-binding domain | HI0933 insert domain-like | 2 | 1 |  |
Smc hinge domain | Tropomyosin | 2 | 1 |  |
F-box domain | alpha-D-mannose-specific plant lectins | 2 | 1 |  |
Ran binding protein zinc finger-like | Translation proteins | 2 | 1 |  |
Serine metabolism enzymes domain | ACT-like | 2 | 2 |  |
Chaperone J-domain | HSC20 (HSCB), C-terminal oligomerisation domain | 2 | 1 |  |
Plus3-like | GYF domain | 2 | 1 |  |
UraD-Like | Transthyretin (synonym: prealbumin) | 2 | 1 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 2 | 1 |  |
TAZ domain | TAZ domain | 2 | 1 |  |
Dcp2 domain-like | Nudix | 2 | 1 |  |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 2 | 2 |  |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | alpha/beta-Hydrolases | 2 | 2 |  |
Putative isomerase YbhE | Quinoprotein alcohol dehydrogenase-like | 2 | 1 |  |
Aldolase | Aminoacid dehydrogenase-like, N-terminal domain | 2 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 2 | 1 |  |
Ribonuclease H-like | RuvA domain 2-like | 2 | 2 |  |
Nucleotidyltransferase | EF-hand | 2 | 1 |  |
BRCT domain | ADP-ribosylation | 2 | 2 |  |
S15/NS1 RNA-binding domain | Class II aaRS ABD-related | 2 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | Enolase C-terminal domain-like | 2 | 1 |  |
Protein kinase-like (PK-like) | HSP20-like chaperones | 2 | 2 |  |
L30e-like | alpha/beta knot | 2 | 1 |  |
Formate/glycerate dehydrogenase catalytic domain-like | ACT-like | 2 | 2 |  |
Enolase N-terminal domain-like | alpha/beta-Hydrolases | 2 | 1 |  |
RING/U-box | Ran binding protein zinc finger-like | 2 | 1 |  |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 |  |
ARM repeat | SH3-domain | 2 | 2 |  |
SWIB/MDM2 domain | CCCH zinc finger | 2 | 1 |  |
F-box domain | Clavaminate synthase-like | 2 | 2 |  |
RNA-binding domain, RBD | WW domain | 2 | 1 |  |
F-box domain | NHL repeat | 2 | 2 |  |
Formyltransferase | FMT C-terminal domain-like | 2 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | Protein kinase-like (PK-like) | 2 | 2 |  |
Ribosomal L27 protein-like | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 |  |
cAMP-binding domain-like | ALDH-like | 2 | 2 |  |
Acyl-CoA N-acyltransferases (Nat) | Bromodomain | 2 | 1 |  |
CarD-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
DHS-like NAD/FAD-binding domain | Enolase C-terminal domain-like | 2 | 1 |  |
Plus3-like | CCCH zinc finger | 2 | 1 |  |
CBS-domain pair | Inosine monophosphate dehydrogenase (IMPDH) | 2 | 1 |  |
Rudiment single hybrid motif | Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor | 2 | 1 |  |
Rad51 N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Aspartate/glutamate racemase | Aspartate/glutamate racemase | 2 | 1 |  |
Ribonuclease H-like | Nucleic acid-binding proteins | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | FAD/NAD(P)-binding domain | 2 | 1 |  |
HAD-like | dsRNA-binding domain-like | 2 | 2 |  |
FAD/NAD(P)-binding domain | Trimeric LpxA-like enzymes | 2 | 2 |  |
Thioredoxin-like | Ypt/Rab-GAP domain of gyp1p | 2 | 1 |  |
HD-domain/PDEase-like | TGS-like | 2 | 2 |  |
Activator of Hsp90 ATPase, Aha1 | Bet v1-like | 2 | 1 |  |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 2 | 1 |  |
PGBD-like | DnaJ/Hsp40 cysteine-rich domain | 2 | 1 |  |
Periplasmic binding protein-like II | GlnB-like | 2 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | HAD-like | 2 | 2 |  |
YjeF N-terminal domain-like | FMN-binding split barrel | 2 | 1 |  |
Surp module (SWAP domain) | ENTH/VHS domain | 2 | 2 |  |
Insert subdomain of RNA polymerase alpha subunit | C-terminal domain of RNA polymerase alpha subunit | 2 | 1 |  |
PX domain | BAR/IMD domain-like | 2 | 2 |  |
ACP-like | Trimeric LpxA-like enzymes | 2 | 2 |  |
Methylglyoxal synthase-like | Cytidine deaminase-like | 2 | 1 |  |
cAMP-binding domain-like | cAMP-binding domain-like | 2 | 2 |  |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite/Sulfite reductase N-terminal domain-like | 2 | 2 |  |
Actin depolymerizing proteins | C-terminal, gelsolin-like domain of Sec23/24 | 2 | 1 |  |
FAD/NAD(P)-binding domain | ACP-like | 2 | 2 |  |
Mannose-binding lectins | Mannose-binding lectins | 2 | 1 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 2 | 1 |  |
Ribose/Galactose isomerase RpiB/AlsB | RmlC-like cupins | 2 | 1 |  |
NTF2-like | Probable bacterial effector-binding domain | 2 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Citrate synthase | 2 | 1 |  |
TRAF domain-like | Kix domain of CBP (creb binding protein) | 2 | 1 |  |
PYP-like sensor domain (PAS domain) | F-box domain | 2 | 2 |  |
PsbU/PolX domain-like | Nucleotidyltransferase | 2 | 1 |  |
Enolase C-terminal domain-like | alpha/beta-Hydrolases | 2 | 1 |  |
NAD(P)-binding Rossmann-fold domains | UDP-Glycosyltransferase/glycogen phosphorylase | 2 | 2 |  |
L domain-like | Cysteine proteinases | 2 | 2 |  |
GYF domain | SET domain | 2 | 1 |  |
Urease, gamma-subunit | Composite domain of metallo-dependent hydrolases | 2 | 2 |  |
Dihydrofolate reductase-like | YbiA-like | 2 | 1 |  |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 2 | 1 |  |
vWA-like | SPOC domain-like | 2 | 2 |  |
Nucleotidyltransferase | TGS-like | 2 | 2 |  |
WD40 repeat-like | Bromodomain | 2 | 1 |  |
DHS-like NAD/FAD-binding domain | Enolase N-terminal domain-like | 2 | 1 |  |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 2 | 1 |  |
Class I glutamine amidotransferase-like | ADC synthase | 2 | 1 |  |
Ribonuclease H-like | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 |  |
GST C-terminal domain-like | Ypt/Rab-GAP domain of gyp1p | 2 | 1 |  |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | Nucleic acid-binding proteins | 2 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | Enolase N-terminal domain-like | 2 | 1 |  |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | Obg GTP-binding protein C-terminal domain | 2 | 1 |  |
BRCT domain | Domain of poly(ADP-ribose) polymerase | 2 | 2 |  |
PDZ domain-like | TPR-like | 2 | 1 |  |
FYVE/PHD zinc finger | SAND domain-like | 2 | 1 |  |
Photosystem I subunits PsaA/PsaB | Photosystem I subunits PsaA/PsaB | 2 | 2 |  |
FYVE/PHD zinc finger | PUA domain-like | 2 | 1 |  |
Ribosomal protein S2 | Nucleotide-diphospho-sugar transferases | 2 | 1 |  |
Outer arm dynein light chain 1 | Protein kinase-like (PK-like) | 2 | 2 |  |
Concanavalin A-like lectins/glucanases | HSP20-like chaperones | 2 | 2 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Alpha subunit of glutamate synthase, C-terminal domain | 2 | 2 |  |
Class I glutamine amidotransferase-like | Ribulose-phoshate binding barrel | 2 | 1 |  |
Translational machinery components | C-terminal domain of RNA polymerase alpha subunit | 2 | 1 |  |
HMA, heavy metal-associated domain | Toll/Interleukin receptor TIR domain | 2 | 1 |  |
Cullin repeat-like | Skp1 dimerisation domain-like | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | TRCF domain-like | 2 | 1 |  |
gp5 N-terminal domain-like | Phage fibre proteins | 2 | 2 |  |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 2 | 2 |  |
NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 2 | 2 |  |
Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, substrate-binding domain | 2 | 1 |  |
F-box domain | Leucine zipper domain | 2 | 1 |  |
cAMP-binding domain-like | Protein kinase-like (PK-like) | 2 | 2 |  |
Six-hairpin glycosidases | AbfB domain | 2 | 1 |  |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 2 |  |
Restriction endonuclease-like | RuvA domain 2-like | 2 | 2 |  |
BRCT domain | WGR domain-like | 2 | 2 |  |
Cysteine proteinases | Protein kinase-like (PK-like) | 2 | 2 |  |
RNA-binding domain, RBD | Clavaminate synthase-like | 2 | 1 |  |
"Winged helix" DNA-binding domain | F1F0 ATP synthase subunit A | 2 | 1 |  |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleotidylyl transferase | 2 | 1 |  |
ATP-dependent DNA ligase DNA-binding domain | BRCT domain | 2 | 1 |  |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 |  |
Chaperone J-domain | Homeodomain-like | 2 | 1 |  |
RBP11-like subunits of RNA polymerase | C-terminal domain of RNA polymerase alpha subunit | 2 | 1 |  |
ADP-ribosylation | Hemopexin-like domain | 2 | 2 |  |
Thioredoxin-like | ERP29 C domain-like | 2 | 1 |  |
Nitrite and sulphite reductase 4Fe-4S domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 2 | 2 |  |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 2 | 2 |  |
Concanavalin A-like lectins/glucanases | RING/U-box | 2 | 1 |  |
Cysteine-rich domain | Cysteine-rich domain | 2 | 2 |  |
Translation proteins SH3-like domain | Ribosomal protein S19 | 2 | 1 |  |
Actin-like ATPase domain | AF1104-like | 2 | 1 |  |
Probable bacterial effector-binding domain | Probable bacterial effector-binding domain | 2 | 2 |  |
NSFL1 (p97 ATPase) cofactor p47, SEP domain | Ubiquitin-like | 2 | 2 |  |
cAMP-binding domain-like | Thioesterase/thiol ester dehydrase-isomerase | 2 | 1 |  |
PDZ domain-like | PDZ domain-like | 2 | 1 |  |
Domain of the SRP/SRP receptor G-proteins | Signal peptide-binding domain | 2 | 1 |  |
FAD/NAD(P)-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 |  |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 2 | 1 |  |
Formate/glycerate dehydrogenase catalytic domain-like | Serine metabolism enzymes domain | 2 | 2 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 2 | 1 |  |
Thioredoxin-like | FAD-dependent thiol oxidase | 2 | 1 |  |
(Phosphotyrosine protein) phosphatases II | (Phosphotyrosine protein) phosphatases II | 2 | 1 |  |
Transmembrane di-heme cytochromes | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) | 2 | 1 |  |
SMAD/FHA domain | Phospholipase D/nuclease | 2 | 2 |  |
Glycerol-3-phosphate (1)-acyltransferase | EF-hand | 2 | 1 |  |
GYF domain | CCCH zinc finger | 2 | 1 |  |
HIT/MYND zinc finger-like | HIT/MYND zinc finger-like | 2 | 1 |  |
RuvA domain 2-like | Nucleic acid-binding proteins | 2 | 2 |  |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Eukaryotic type KH-domain (KH-domain type I) | 2 | 1 |  |
Ran binding protein zinc finger-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
Toll/Interleukin receptor TIR domain | UBA-like | 2 | 2 |  |
Nucleotidylyl transferase | Nucleic acid-binding proteins | 2 | 1 |  |
Diaminopimelate epimerase-like | Diaminopimelate epimerase-like | 2 | 1 |  |
TPR-like | Ankyrin repeat | 2 | 2 |  |
SAP domain | DNase I-like | 2 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | RuvA domain 2-like | 2 | 1 |  |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Sm-like ribonucleoproteins | 2 | 2 |  |
Hypothetical protein c14orf129, hspc210 | TPR-like | 2 | 1 |  |
PUA domain-like | Nucleotidylyl transferase | 2 | 1 |  |
Toll/Interleukin receptor TIR domain | Elongation factor Ts (EF-Ts), dimerisation domain | 2 | 2 |  |
Riboflavin synthase domain-like | Riboflavin synthase domain-like | 2 | 1 |  |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 2 | 1 |  |
PP2C-like | cAMP-binding domain-like | 2 | 2 |  |
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain | Alkaline phosphatase-like | 2 | 1 |  |
DNA polymerase beta, N-terminal domain-like | Nucleotidyltransferase | 2 | 1 |  |
Tricorn protease domain 2 | WD40 repeat-like | 2 | 2 |  |
CAD & PB1 domains | UBA-like | 2 | 1 |  |
RuvA domain 2-like | RuvA domain 2-like | 2 | 2 |  |
Acyl-CoA binding protein | Kelch motif | 2 | 2 |  |
Ran binding protein zinc finger-like | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 2 | 1 |  |
Adenine nucleotide alpha hydrolases-like | Thioredoxin-like | 2 | 2 |  |
HD-domain/PDEase-like | EF-hand | 2 | 1 |  |
Rhomboid-like | UBA-like | 2 | 1 |  |
PH domain-like | BSD domain-like | 2 | 1 |  |
Retrovirus zinc finger-like domains | RNA-binding domain, RBD | 2 | 2 |  |
Tex N-terminal region-like | Ribonuclease H-like | 2 | 2 |  |
FYVE/PHD zinc finger | CCCH zinc finger | 2 | 1 |  |
Obg GTP-binding protein N-terminal domain | Obg GTP-binding protein C-terminal domain | 2 | 1 |  |
HMG-box | HMG-box | 2 | 2 |  |
Tubulin nucleotide-binding domain-like | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 2 | 1 |  |
HCP-like | Homing endonucleases | 2 | 1 |  |
HIT/MYND zinc finger-like | RING/U-box | 2 | 1 |  |
Nqo1 FMN-binding domain-like | Nqo1 middle domain-like | 2 | 1 |  |
UBC-like | RING/U-box | 2 | 2 |  |
Molybdenum cofactor biosynthesis proteins | Molybdenum cofactor biosynthesis proteins | 2 | 2 |  |
GroEL equatorial domain-like | DNA-binding domain | 2 | 1 |  |
Cytidine deaminase-like | Cytidine deaminase-like | 2 | 1 |  |
BRCT domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 |  |
ARM repeat | alpha/beta-Hydrolases | 2 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | FMN-linked oxidoreductases | 2 | 2 |  |
FAD/NAD(P)-binding domain | Acetyl-CoA synthetase-like | 2 | 2 |  |
Histone-fold | NAP-like | 2 | 1 |  |
PH domain-like | Prismane protein-like | 1 | 1 |  |
Acyl-CoA binding protein | Ankyrin repeat | 1 | 1 |  |
TGS-like | ACT-like | 1 | 1 |  |
Carbohydrate phosphatase | HAD-like | 1 | 1 |  |
Carbamate kinase-like | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 |  |
HMA, heavy metal-associated domain | NosL/MerB-like | 1 | 1 |  |
PYP-like sensor domain (PAS domain) | Kelch motif | 1 | 1 |  |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 |  |
Cryptochrome/photolyase, N-terminal domain | alpha/beta-Hydrolases | 1 | 1 |  |
Cysteine proteinases | Calpain large subunit, middle domain (domain III) | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Cytochrome c oxidase subunit II-like, transmembrane region | 1 | 1 |  |
TGS-like | Class II aaRS ABD-related | 1 | 1 |  |
HMA, heavy metal-associated domain | Cu,Zn superoxide dismutase-like | 1 | 1 |  |
Fe-S cluster assembly (FSCA) domain-like | FKBP-like | 1 | 1 |  |
Toll/Interleukin receptor TIR domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 |  |
Helical scaffold and wing domains of SecA | Helical scaffold and wing domains of SecA | 1 | 1 |  |
Ubiquitin-like | Bromodomain | 1 | 1 |  |
ARM repeat | Clavaminate synthase-like | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | ADP-ribosylation | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain III | 1 | 1 |  |
Pectin lyase-like | Pectin lyase-like | 1 | 1 |  |
Nucleotide-binding domain | Nucleotide-binding domain | 1 | 1 |  |
PRP4-like | Functional domain of the splicing factor Prp18 | 1 | 1 |  |
Staphylococcal nuclease | Staphylococcal nuclease | 1 | 1 |  |
Phosphoglucomutase, C-terminal domain | Phosphoglucomutase, C-terminal domain | 1 | 1 |  |
Thioredoxin-like | Six-hairpin glycosidases | 1 | 1 |  |
Aldolase | Ribulose-phoshate binding barrel | 1 | 1 |  |
PH domain-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 |  |
dsRNA-binding domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
"Winged helix" DNA-binding domain | DNA-binding pseudobarrel domain | 1 | 1 |  |
WD40 repeat-like | Peptidase/esterase 'gauge' domain | 1 | 1 |  |
RNA-binding domain, RBD | N-terminal domain of alpha and beta subunits of F1 ATP synthase | 1 | 1 |  |
alpha-helical ferredoxin | FAD/NAD(P)-binding domain | 1 | 1 |  |
UBC-like | Endosomal sorting complex assembly domain | 1 | 1 |  |
L domain-like | DNA-binding pseudobarrel domain | 1 | 1 |  |
TAF(II)230 TBP-binding fragment | Bromodomain | 1 | 1 |  |
SSo0622-like | Kelch motif | 1 | 1 |  |
Cyclin-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Nucleic acid-binding proteins | Ribosomal protein S7 | 1 | 1 |  |
RNA-binding domain, RBD | DPP6 N-terminal domain-like | 1 | 1 |  |
L9 N-domain-like | Ribosomal protein L9 C-domain | 1 | 1 |  |
Typo IV secretion system protein TraC | NTF2-like | 1 | 1 |  |
Cna protein B-type domain | Carboxypeptidase regulatory domain-like | 1 | 1 |  |
ALDH-like | ALDH-like | 1 | 1 |  |
Nucleotide-diphospho-sugar transferases | ARM repeat | 1 | 1 |  |
Aquaporin-like | HMA, heavy metal-associated domain | 1 | 1 |  |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | PLP-dependent transferases | 1 | 1 |  |
Prokaryotic type I DNA topoisomerase | Retrovirus zinc finger-like domains | 1 | 1 |  |
Metallo-dependent hydrolases | Metallo-dependent hydrolases | 1 | 1 |  |
L domain-like | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 |  |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | ARM repeat | 1 | 1 |  |
POZ domain | Galactose-binding domain-like | 1 | 1 |  |
"Winged helix" DNA-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 |  |
Cytochrome c oxidase subunit II-like, transmembrane region | Cupredoxins | 1 | 1 |  |
Nucleic acid-binding proteins | SH2 domain | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Carbohydrate phosphatase | 1 | 1 |  |
S15/NS1 RNA-binding domain | HydB/Nqo4-like | 1 | 1 |  |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | ClpP/crotonase | 1 | 1 |  |
alpha/beta knot | Nucleic acid-binding proteins | 1 | 1 |  |
YggU-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 |  |
Zinc beta-ribbon | Zinc beta-ribbon | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 |  |
Cytochrome b559 subunits | Photosystem II reaction center protein L, PsbL | 1 | 1 |  |
FAD/NAD(P)-binding domain | DNA-binding domain | 1 | 1 |  |
WD40 repeat-like | Ribonuclease H-like | 1 | 1 |  |
Cytochrome P450 | Calcium-dependent phosphotriesterase | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | Domain of poly(ADP-ribose) polymerase | 1 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | Retrovirus zinc finger-like domains | 1 | 1 |  |
RNI-like | SGNH hydrolase | 1 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 1 | 1 |  |
YgbK-like | Aldolase | 1 | 1 |  |
CBS-domain pair | DNA-binding pseudobarrel domain | 1 | 1 |  |
Protein kinase-like (PK-like) | NTF2-like | 1 | 1 |  |
Nucleotidyltransferase | ACT-like | 1 | 1 |  |
Phage fibre proteins | Phage fibre proteins | 1 | 1 |  |
XRCC4, N-terminal domain | XRCC4, C-terminal oligomerization domain | 1 | 1 |  |
POZ domain | Pentapeptide repeat-like | 1 | 1 |  |
Ribonuclease Rh-like | Protein kinase-like (PK-like) | 1 | 1 |  |
vWA-like | C-terminal domain of Ku80 | 1 | 1 |  |
Sec1/munc18-like (SM) proteins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Protein kinase-like (PK-like) | PR-1-like | 1 | 1 |  |
Protein kinase-like (PK-like) | beta-lactamase/transpeptidase-like | 1 | 1 |  |
F-box domain | Glutathione synthetase ATP-binding domain-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | UBC-like | 1 | 1 |  |
gp5 N-terminal domain-like | Ankyrin repeat | 1 | 1 |  |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | alpha/beta-Hydrolases | 1 | 1 |  |
WD40 repeat-like | Galactose oxidase, central domain | 1 | 1 |  |
RING/U-box | Leucine zipper domain | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | F-box domain | 1 | 1 |  |
Pseudouridine synthase | PUA domain-like | 1 | 1 |  |
Calponin-homology domain, CH-domain | ARM repeat | 1 | 1 |  |
DNA clamp | DNA clamp | 1 | 1 |  |
Dimeric alpha+beta barrel | Dehydroquinate synthase-like | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 1 | 1 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 |  |
Toll/Interleukin receptor TIR domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 |  |
Band 7/SPFH domain | DNA/RNA polymerases | 1 | 1 |  |
Homeodomain-like | L domain-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Cupredoxins | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | PLP-dependent transferases | 1 | 1 |  |
CBS-domain pair | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 |  |
Rudiment single hybrid motif | ClpP/crotonase | 1 | 1 |  |
FYVE/PHD zinc finger | RNI-like | 1 | 1 |  |
Nucleic acid-binding proteins | RNA-binding domain, RBD | 1 | 1 |  |
Ribosomal protein S2 | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
UDP-Glycosyltransferase/glycogen phosphorylase | GHMP Kinase, C-terminal domain | 1 | 1 |  |
Lipoxigenase | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 |  |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 1 | 1 |  |
Phage tail proteins | Tricorn protease N-terminal domain | 1 | 1 |  |
Thioredoxin-like | VC0467-like | 1 | 1 |  |
HMA, heavy metal-associated domain | FAD/NAD(P)-binding domain | 1 | 1 |  |
Ribosomal protein S8 | RuBisCo, C-terminal domain | 1 | 1 |  |
Translation proteins | Nucleotide-diphospho-sugar transferases | 1 | 1 |  |
SAP domain | CCCH zinc finger | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | BRCT domain | 1 | 1 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | Cytochrome c oxidase subunit II-like, transmembrane region | 1 | 1 |  |
CCCH zinc finger | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | Casein kinase II beta subunit | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | 4Fe-4S ferredoxins | 1 | 1 |  |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | TATA-box binding protein-like | 1 | 1 |  |
SPOC domain-like | C-terminal domain of Ku80 | 1 | 1 |  |
Nucleotide-diphospho-sugar transferases | RmlC-like cupins | 1 | 1 |  |
Cna protein B-type domain | Cna protein B-type domain | 1 | 1 |  |
FMN-dependent nitroreductase-like | FMN-dependent nitroreductase-like | 1 | 1 |  |
Phosphoglycerate mutase-like | Phosphoglycerate mutase-like | 1 | 1 |  |
UDP-Glycosyltransferase/glycogen phosphorylase | Ribosomal protein S5 domain 2-like | 1 | 1 |  |
Zinc-binding domain of translation initiation factor 2 beta | ARM repeat | 1 | 1 |  |
PH domain-like | "Winged helix" DNA-binding domain | 1 | 1 |  |
Serpins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
TPR-like | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 1 | 1 |  |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | Phosphoglycerate kinase | 1 | 1 |  |
FKBP-like | Rhodanese/Cell cycle control phosphatase | 1 | 1 |  |
RuvA domain 2-like | SH2 domain | 1 | 1 |  |
Outer arm dynein light chain 1 | RNI-like | 1 | 1 |  |
SAP domain | ADP-ribosylation | 1 | 1 |  |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 |  |
SufE/NifU | NadA-like | 1 | 1 |  |
Class II aaRS and biotin synthetases | Class II aaRS and biotin synthetases | 1 | 1 |  |
SNARE-like | SNARE-like | 1 | 1 |  |
Periplasmic binding protein-like I | Periplasmic binding protein-like I | 1 | 1 |  |
ARM repeat | Chaperone J-domain | 1 | 1 |  |
Chromo domain-like | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 |  |
ARM repeat | alpha/beta knot | 1 | 1 |  |
Ankyrin repeat | Translation initiation factor IF3, N-terminal domain | 1 | 1 |  |
AN1-like Zinc finger | beta-beta-alpha zinc fingers | 1 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | PLP-dependent transferases | 1 | 1 |  |
Peptidase/esterase 'gauge' domain | SNARE fusion complex | 1 | 1 |  |
Starch-binding domain-like | Nucleic acid-binding proteins | 1 | 1 |  |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | Clavaminate synthase-like | 1 | 1 |  |
F-box domain | NTF2-like | 1 | 1 |  |
CCCH zinc finger | WD40 repeat-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | GIY-YIG endonuclease | 1 | 1 |  |
ClpP/crotonase | Thiolase-like | 1 | 1 |  |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Elongation factor TFIIS domain 2 | 1 | 1 |  |
Tudor/PWWP/MBT | Tudor/PWWP/MBT | 1 | 1 |  |
Homeodomain-like | Tetracyclin repressor-like, C-terminal domain | 1 | 1 |  |
HAD-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
Starch-binding domain-like | Starch-binding domain-like | 1 | 1 |  |
PreATP-grasp domain | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 |  |
F-box domain | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
Ribosomal protein S8 | Ribosomal protein L36 | 1 | 1 |  |
Acid proteases | Nucleic acid-binding proteins | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | Acid proteases | 1 | 1 |  |
PYP-like sensor domain (PAS domain) | Galactose oxidase, central domain | 1 | 1 |  |
DNA-glycosylase | Nudix | 1 | 1 |  |
Endosomal sorting complex assembly domain | VPS28 C-terminal domain-like | 1 | 1 |  |
Ribosomal protein S2 | F1F0 ATP synthase subunit A | 1 | 1 |  |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 1 | 1 |  |
L domain-like | V-type ATP synthase subunit C | 1 | 1 |  |
DNA ligase/mRNA capping enzyme, catalytic domain | RNA-binding domain, RBD | 1 | 1 |  |
beta-beta-alpha zinc fingers | Ankyrin repeat | 1 | 1 |  |
Carbon-nitrogen hydrolase | Adenine nucleotide alpha hydrolases-like | 1 | 1 |  |
Ribosomal protein L16p/L10e | Ribosomal protein L14 | 1 | 1 |  |
Phage fibre proteins | Ankyrin repeat | 1 | 1 |  |
DNA primase core | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
HCP-like | Argininosuccinate synthetase, C-terminal domain | 1 | 1 |  |
Plant lectins/antimicrobial peptides | Barwin-like endoglucanases | 1 | 1 |  |
Clavaminate synthase-like | Protein kinase-like (PK-like) | 1 | 1 |  |
Tricorn protease domain 2 | alpha/beta-Hydrolases | 1 | 1 |  |
"Winged helix" DNA-binding domain | UBA-like | 1 | 1 |  |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | RING/U-box | 1 | 1 |  |
alpha/beta-Hydrolases | HCP-like | 1 | 1 |  |
NAC domain | NAC domain | 1 | 1 |  |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like II | 1 | 1 |  |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | ACT-like | 1 | 1 |  |
TGS-like | ThrRS/AlaRS common domain | 1 | 1 |  |
FYVE/PHD zinc finger | Actin-like ATPase domain | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 |  |
ARM repeat | Acid proteases | 1 | 1 |  |
gp5 N-terminal domain-like | alpha/beta-Hydrolases | 1 | 1 |  |
PAH2 domain | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 |  |
Ribonuclease H-like | Alkaline phosphatase-like | 1 | 1 |  |
Nucleotide-diphospho-sugar transferases | Nucleotide-diphospho-sugar transferases | 1 | 1 |  |
PUA domain-like | eIF1-like | 1 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | Protein kinase-like (PK-like) | 1 | 1 |  |
Cyclin-like | L domain-like | 1 | 1 |  |
Elongation factor TFIIS domain 2 | Zinc beta-ribbon | 1 | 1 |  |
PA domain | EGF/Laminin | 1 | 1 |  |
Phosphoenolpyruvate/pyruvate domain | ENTH/VHS domain | 1 | 1 |  |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 |  |
RNA-binding domain, RBD | Surp module (SWAP domain) | 1 | 1 |  |
Aldolase | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 1 | 1 |  |
Oxysterol-binding protein-like | LeuD/IlvD-like | 1 | 1 |  |
Nucleotidylyl transferase | tRNA-binding arm | 1 | 1 |  |
POZ domain | Putative isomerase YbhE | 1 | 1 |  |
Eukaryotic RPB5 N-terminal domain | Eukaryotic RPB5 N-terminal domain | 1 | 1 |  |
Staphylococcal nuclease | Tudor/PWWP/MBT | 1 | 1 |  |
ARM repeat | Ribosomal protein L4 | 1 | 1 |  |
F-box domain | FtsH protease domain-like | 1 | 1 |  |
Terpenoid synthases | Protein kinase-like (PK-like) | 1 | 1 |  |
Putative cyclase | YjgF-like | 1 | 1 |  |
GroES-like | DNA/RNA polymerases | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | TK C-terminal domain-like | 1 | 1 |  |
PDZ domain-like | Rubredoxin-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Thiamin diphosphate-binding fold (THDP-binding) | 1 | 1 |  |
D-aminoacid aminotransferase-like PLP-dependent enzymes | D-aminoacid aminotransferase-like PLP-dependent enzymes | 1 | 1 |  |
Homeodomain-like | F-box domain | 1 | 1 |  |
lambda repressor-like DNA-binding domains | RmlC-like cupins | 1 | 1 |  |
F-box domain | SET domain | 1 | 1 |  |
CBS-domain pair | FAD-binding/transporter-associated domain-like | 1 | 1 |  |
DNA-glycosylase | DNase I-like | 1 | 1 |  |
beta-Galactosidase/glucuronidase domain | Galactose mutarotase-like | 1 | 1 |  |
ACP-like | ACP-like | 1 | 1 |  |
Six-hairpin glycosidases | Tautomerase/MIF | 1 | 1 |  |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 |  |
DEK C-terminal domain | SWIB/MDM2 domain | 1 | 1 |  |
Leucine zipper domain | Leucine zipper domain | 1 | 1 |  |
Ankyrin repeat | RCC1/BLIP-II | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | Metallo-hydrolase/oxidoreductase | 1 | 1 |  |
PLP-dependent transferases | (Trans)glycosidases | 1 | 1 |  |
5' to 3' exonuclease, C-terminal subdomain | Chromo domain-like | 1 | 1 |  |
Protein kinase-like (PK-like) | RuBisCo, C-terminal domain | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | Phosphohistidine domain | 1 | 1 |  |
Carbohydrate phosphatase | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
WGR domain-like | Phosphofructokinase | 1 | 1 |  |
Ribosomal protein L14 | Translational machinery components | 1 | 1 |  |
Myosin S1 fragment, N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 |  |
gp5 N-terminal domain-like | gp5 N-terminal domain-like | 1 | 1 |  |
Fucose-specific lectin | Fucose-specific lectin | 1 | 1 |  |
Phosphoglycerate kinase | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
POZ domain | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
Starch-binding domain-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 |  |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | Cytochrome c oxidase subunit II-like, transmembrane region | 1 | 1 |  |
HIT/MYND zinc finger-like | Protein kinase-like (PK-like) | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | Protein kinase-like (PK-like) | 1 | 1 |  |
Acyl-CoA dehydrogenase NM domain-like | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 |  |
GYF domain | RNA-binding domain, RBD | 1 | 1 |  |
Protein kinase-like (PK-like) | Homeodomain-like | 1 | 1 |  |
Protein kinase-like (PK-like) | HCP-like | 1 | 1 |  |
HIT/MYND zinc finger-like | SET domain | 1 | 1 |  |
GroES-like | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 |  |
Rhomboid-like | Ran binding protein zinc finger-like | 1 | 1 |  |
Ribonuclease H-like | DNase I-like | 1 | 1 |  |
GST C-terminal domain-like | Nucleotidylyl transferase | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | DNA/RNA polymerases | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | alpha/beta-Hydrolases | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | SH2 domain | 1 | 1 |  |
PUA domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
F-box domain | Calcium-dependent phosphotriesterase | 1 | 1 |  |
Leucine zipper domain | Chaperone J-domain | 1 | 1 |  |
Aldolase | HAD-like | 1 | 1 |  |
TPR-like | F-box domain | 1 | 1 |  |
FAD/NAD(P)-binding domain | NosL/MerB-like | 1 | 1 |  |
Tex N-terminal region-like | Nucleic acid-binding proteins | 1 | 1 |  |
MurE/MurF N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 1 | 1 |  |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | Cupredoxins | 1 | 1 |  |
Protein kinase-like (PK-like) | Cytochrome P450 | 1 | 1 |  |
N-terminal domain of adenylylcyclase associated protein, CAP | C-terminal domain of adenylylcyclase associated protein | 1 | 1 |  |
Nucleic acid-binding proteins | SMAD/FHA domain | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 1 | 1 |  |
SPOC domain-like | SAP domain | 1 | 1 |  |
"Winged helix" DNA-binding domain | GAF domain-like | 1 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | ARM repeat | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | FAD/NAD(P)-binding domain | 1 | 1 |  |
WD40 repeat-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
HCP-like | Phospholipase D/nuclease | 1 | 1 |  |
MurE/MurF N-terminal domain | MurD-like peptide ligases, catalytic domain | 1 | 1 |  |
Protein prenylyltransferase | L domain-like | 1 | 1 |  |
Nucleic acid-binding proteins | UBA-like | 1 | 1 |  |
Nucleic acid-binding proteins | "Winged helix" DNA-binding domain | 1 | 1 |  |
L domain-like | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 |  |
Zn-binding ribosomal proteins | Ribosomal protein S18 | 1 | 1 |  |
WD40 repeat-like | Nucleoporin domain | 1 | 1 |  |
Homeodomain-like | Toll/Interleukin receptor TIR domain | 1 | 1 |  |
Putative isomerase YbhE | ARM repeat | 1 | 1 |  |
Protein kinase-like (PK-like) | Acyl-CoA dehydrogenase NM domain-like | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Thiolase-like | 1 | 1 |  |
RNI-like | WD40 repeat-like | 1 | 1 |  |
Second domain of FERM | Prismane protein-like | 1 | 1 |  |
Acid proteases | Acid proteases | 1 | 1 |  |
L domain-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 |  |
ARM repeat | Concanavalin A-like lectins/glucanases | 1 | 1 |  |
Translation proteins SH3-like domain | Translation proteins SH3-like domain | 1 | 1 |  |
FAD/NAD(P)-binding domain | "Winged helix" DNA-binding domain | 1 | 1 |  |
HMG-box | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Thiolase-like | WD40 repeat-like | 1 | 1 |  |
Cysteine proteinases | Thioredoxin-like | 1 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | YgbK-like | 1 | 1 |  |
Tex N-terminal region-like | RuvA domain 2-like | 1 | 1 |  |
Kix domain of CBP (creb binding protein) | Protein kinase-like (PK-like) | 1 | 1 |  |
HSP20-like chaperones | HSP20-like chaperones | 1 | 1 |  |
Zn-dependent exopeptidases | NAC domain | 1 | 1 |  |
FAD-binding/transporter-associated domain-like | DNA-binding pseudobarrel domain | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | RNI-like | 1 | 1 |  |
HMA, heavy metal-associated domain | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 |  |
Multidrug resistance efflux transporter EmrE | (Trans)glycosidases | 1 | 1 |  |
PreATP-grasp domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 |  |
Tudor/PWWP/MBT | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Trimeric LpxA-like enzymes | ARM repeat | 1 | 1 |  |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | Homeodomain-like | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 |  |
TPR-like | RNA-binding domain, RBD | 1 | 1 |  |
RuBisCO, large subunit, small (N-terminal) domain | Ribosomal protein S8 | 1 | 1 |  |
UBC-like | Class II aaRS and biotin synthetases | 1 | 1 |  |
TGS-like | Class II aaRS and biotin synthetases | 1 | 1 |  |
Homeodomain-like | TATA-box binding protein-like | 1 | 1 |  |
Mitochondrial carrier | Mitochondrial carrier | 1 | 1 |  |
Ankyrin repeat | DNA/RNA polymerases | 1 | 1 |  |
FMN-linked oxidoreductases | FAD/NAD(P)-binding domain | 1 | 1 |  |
S-adenosyl-L-methionine-dependent methyltransferases | alpha-D-mannose-specific plant lectins | 1 | 1 |  |
R3H domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
WD40 repeat-like | Cyclophilin-like | 1 | 1 |  |
Acetyl-CoA synthetase-like | Tetracyclin repressor-like, C-terminal domain | 1 | 1 |  |
Nucleic acid-binding proteins | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
DNA-binding pseudobarrel domain | Nucleic acid-binding proteins | 1 | 1 |  |
PreATP-grasp domain | ClpP/crotonase | 1 | 1 |  |
F-box domain | DPP6 N-terminal domain-like | 1 | 1 |  |
Glutathione synthetase ATP-binding domain-like | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | HAD-like | 1 | 1 |  |
WD40 repeat-like | NHL repeat | 1 | 1 |  |
SAP domain | Domain of poly(ADP-ribose) polymerase | 1 | 1 |  |
Putative isomerase YbhE | RING/U-box | 1 | 1 |  |
L domain-like | alpha/beta-Hydrolases | 1 | 1 |  |
Starch-binding domain-like | (Trans)glycosidases | 1 | 1 |  |
RNI-like | RuBisCo, C-terminal domain | 1 | 1 |  |
Zn-dependent exopeptidases | Protein kinase-like (PK-like) | 1 | 1 |  |
Phage fibre proteins | alpha/beta-Hydrolases | 1 | 1 |  |
NagB/RpiA/CoA transferase-like | NagB/RpiA/CoA transferase-like | 1 | 1 |  |
F-box domain | YWTD domain | 1 | 1 |  |
Ankyrin repeat | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Metalloproteases ("zincins"), catalytic domain | OmpA-like | 1 | 1 |  |
Taf5 N-terminal domain-like | WD40 repeat-like | 1 | 1 |  |
Tricorn protease N-terminal domain | Tricorn protease N-terminal domain | 1 | 1 |  |
ARM repeat | BEACH domain | 1 | 1 |  |
Ribulose-phoshate binding barrel | HAD-like | 1 | 1 |  |
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin | 1 | 1 |  |
WGR domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
Cytochrome P450 | Homeodomain-like | 1 | 1 |  |
C-type lectin-like | Protein kinase-like (PK-like) | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | "Winged helix" DNA-binding domain | 1 | 1 |  |
FYVE/PHD zinc finger | Bromodomain | 1 | 1 |  |
PIN domain-like | Nucleic acid-binding proteins | 1 | 1 |  |
Nucleic acid-binding proteins | TPR-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 |  |
Acetyl-CoA synthetase-like | Heme-dependent catalase-like | 1 | 1 |  |
DNA-binding pseudobarrel domain | Ribonuclease H-like | 1 | 1 |  |
HAD-like | RmlC-like cupins | 1 | 1 |  |
FKBP-like | Triger factor/SurA peptide-binding domain-like | 1 | 1 |  |
AraD/HMP-PK domain-like | HAD-like | 1 | 1 |  |
Retrovirus zinc finger-like domains | Actin depolymerizing proteins | 1 | 1 |  |
EF-hand | TPR-like | 1 | 1 |  |
Leukotriene A4 hydrolase N-terminal domain | ARM repeat | 1 | 1 |  |
Subunit IX of photosystem I reaction centre, PsaJ | Zn-binding ribosomal proteins | 1 | 1 |  |
ISP domain | Chlorophyll a-b binding protein | 1 | 1 |  |
Metallo-dependent phosphatases | Metallo-dependent phosphatases | 1 | 1 |  |
N-utilization substance G protein NusG, N-terminal domain | Translation proteins SH3-like domain | 1 | 1 |  |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain I | 1 | 1 |  |
Macro domain-like | HIT-like | 1 | 1 |  |
Ubiquitin-like | HAD-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 |  |
Nucleic acid-binding proteins | Protein kinase-like (PK-like) | 1 | 1 |  |
Retrovirus zinc finger-like domains | Retrovirus zinc finger-like domains | 1 | 1 |  |
Pre-PUA domain | PUA domain-like | 1 | 1 |  |
Poly A polymerase C-terminal region-like | Poly A polymerase C-terminal region-like | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | YgbK-like | 1 | 1 |  |
HIT/MYND zinc finger-like | L domain-like | 1 | 1 |  |
MFS general substrate transporter | Alkaline phosphatase-like | 1 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | Thiolase-like | 1 | 1 |  |
Nucleic acid-binding proteins | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Pili subunits | 1 | 1 |  |
RNA-binding domain, RBD | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Type II DNA topoisomerase | Type II DNA topoisomerase | 1 | 1 |  |
R3H domain | Ankyrin repeat | 1 | 1 |  |
Alpha subunit of glutamate synthase, C-terminal domain | FAD/NAD(P)-binding domain | 1 | 1 |  |
Phosphofructokinase | "Winged helix" DNA-binding domain | 1 | 1 |  |
ARM repeat | F-box domain | 1 | 1 |  |
RNA-binding domain, RBD | ENTH/VHS domain | 1 | 1 |  |
POZ domain | WD40 repeat-like | 1 | 1 |  |
FMN-linked oxidoreductases | alpha-helical ferredoxin | 1 | 1 |  |
Translation proteins | PRC-barrel domain | 1 | 1 |  |
GST C-terminal domain-like | Nucleic acid-binding proteins | 1 | 1 |  |
Mog1p/PsbP-like | CRAL/TRIO domain | 1 | 1 |  |
Ribokinase-like | Thiamin phosphate synthase | 1 | 1 |  |
Subtilisin-like | Cytidine deaminase-like | 1 | 1 |  |
N-terminal domain of MutM-like DNA repair proteins | S13-like H2TH domain | 1 | 1 |  |
RNI-like | NTF2-like | 1 | 1 |  |
PRC-barrel domain | Nucleotide-diphospho-sugar transferases | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | Protein kinase-like (PK-like) | 1 | 1 |  |
Pectin lyase-like | L domain-like | 1 | 1 |  |
FYSH domain | beta-beta-alpha zinc fingers | 1 | 1 |  |
Nucleic acid-binding proteins | F-box domain | 1 | 1 |  |
PreATP-grasp domain | Methylglyoxal synthase-like | 1 | 1 |  |
Pseudo ankyrin repeat-like | TPR-like | 1 | 1 |  |
PIN domain-like | Chromo domain-like | 1 | 1 |  |
ARM repeat | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 1 | 1 |  |
Protease propeptides/inhibitors | PA domain | 1 | 1 |  |
Acyl-CoA N-acyltransferases (Nat) | BRCT domain | 1 | 1 |  |
Lipocalins | Lipocalins | 1 | 1 |  |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 |  |
Acetyl-CoA synthetase-like | Homeodomain-like | 1 | 1 |  |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | alpha-helical ferredoxin | 1 | 1 |  |
WD40 repeat-like | TPR-like | 1 | 1 |  |
SAP domain | WGR domain-like | 1 | 1 |  |
Ribosomal proteins S24e, L23 and L15e | Translation proteins SH3-like domain | 1 | 1 |  |
Phage tail proteins | Ankyrin repeat | 1 | 1 |  |
Ankyrin repeat | Translation initiation factor IF3, C-terminal domain | 1 | 1 |  |
FAD/NAD(P)-binding domain | Thioredoxin-like | 1 | 1 |  |
MetI-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
WW domain | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | DPP6 N-terminal domain-like | 1 | 1 |  |
beta-sandwich domain of Sec23/24 | Ribosomal protein L1 | 1 | 1 |  |
Phosphoenolpyruvate/pyruvate domain | Multidrug resistance efflux transporter EmrE | 1 | 1 |  |
"Winged helix" DNA-binding domain | Acetyl-CoA synthetase-like | 1 | 1 |  |
Chaperone J-domain | beta-beta-alpha zinc fingers | 1 | 1 |  |
Chromo domain-like | Ankyrin repeat | 1 | 1 |  |
Terpenoid synthases | Terpenoid synthases | 1 | 1 |  |
Kelch motif | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Cap-Gly domain | L domain-like | 1 | 1 |  |
Band 7/SPFH domain | Band 7/SPFH domain | 1 | 1 |  |
Glucocorticoid receptor-like (DNA-binding domain) | WGR domain-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | HIT-like | 1 | 1 |  |
JAB1/MPN domain | cAMP-binding domain-like | 1 | 1 |  |
ClpP/crotonase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 |  |
Trigger factor ribosome-binding domain | Triger factor/SurA peptide-binding domain-like | 1 | 1 |  |
DNase I-like | Clavaminate synthase-like | 1 | 1 |  |
"Winged helix" DNA-binding domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 |  |
Metallo-hydrolase/oxidoreductase | TPR-like | 1 | 1 |  |
SNARE-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
UBC-like | UBC-like | 1 | 1 |  |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 1 | 1 |  |
Photosystem II antenna protein-like | beta and beta-prime subunits of DNA dependent RNA-polymerase | 1 | 1 |  |
Acyl-CoA dehydrogenase C-terminal domain-like | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 |  |
TK C-terminal domain-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
UBC-like | Protein kinase-like (PK-like) | 1 | 1 |  |
Arabinanase/levansucrase/invertase | Arabinanase/levansucrase/invertase | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Typo IV secretion system protein TraC | 1 | 1 |  |
ARM repeat | "Winged helix" DNA-binding domain | 1 | 1 |  |
Ribonuclease H-like | Protein kinase-like (PK-like) | 1 | 1 |  |
ACP-like | Heme-dependent catalase-like | 1 | 1 |  |
FAD-binding/transporter-associated domain-like | FAD-binding/transporter-associated domain-like | 1 | 1 |  |
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK | Dihydropteroate synthetase-like | 1 | 1 |  |
PDZ domain-like | E set domains | 1 | 1 |  |
FAD/NAD(P)-binding domain | Heme-dependent catalase-like | 1 | 1 |  |
HAD-like | Nucleotide-diphospho-sugar transferases | 1 | 1 |  |
Eukaryotic type KH-domain (KH-domain type I) | RNA-binding domain, RBD | 1 | 1 |  |
Type II DNA topoisomerase | GyrA/ParC C-terminal domain-like | 1 | 1 |  |
TPR-like | Casein kinase II beta subunit | 1 | 1 |  |
DNA/RNA polymerases | DNA/RNA polymerases | 1 | 1 |  |
Zn-dependent exopeptidases | L domain-like | 1 | 1 |  |
Photosystem II 10 kDa phosphoprotein PsbH | Transmembrane di-heme cytochromes | 1 | 1 |  |
HCP-like | RNI-like | 1 | 1 |  |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 |  |
L domain-like | beta and beta-prime subunits of DNA dependent RNA-polymerase | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | Calpain large subunit, middle domain (domain III) | 1 | 1 |  |
DPP6 N-terminal domain-like | HCP-like | 1 | 1 |  |
Arabinanase/levansucrase/invertase | Nucleotide-diphospho-sugar transferases | 1 | 1 |  |
Concanavalin A-like lectins/glucanases | Cysteine proteinases | 1 | 1 |  |
Protein kinase-like (PK-like) | Class II aaRS ABD-related | 1 | 1 |  |
Photosystem II reaction center protein K, PsbK | Photosystem II reaction center protein I, PsbI | 1 | 1 |  |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | Cupredoxins | 1 | 1 |  |
PUA domain-like | SWIB/MDM2 domain | 1 | 1 |  |
Cna protein B-type domain | Starch-binding domain-like | 1 | 1 |  |
Trigger factor ribosome-binding domain | FKBP-like | 1 | 1 |  |
Acyl-CoA N-acyltransferases (Nat) | RNA-binding domain, RBD | 1 | 1 |  |
F-box domain | Pectin lyase-like | 1 | 1 |  |
Homeodomain-like | Photosystem I subunits PsaA/PsaB | 1 | 1 |  |
TATA-box binding protein-like | DNA-glycosylase | 1 | 1 |  |
Bromodomain | Nucleic acid-binding proteins | 1 | 1 |  |
Quinoprotein alcohol dehydrogenase-like | C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase | 1 | 1 |  |
ARM repeat | FabD/lysophospholipase-like | 1 | 1 |  |
Caspase-like | DNase I-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | NTF2-like | 1 | 1 |  |
ssDNA-binding transcriptional regulator domain | ssDNA-binding transcriptional regulator domain | 1 | 1 |  |
Ribonuclease Rh-like | Formin homology 2 domain (FH2 domain) | 1 | 1 |  |
AF0104/ALDC/Ptd012-like | AF0104/ALDC/Ptd012-like | 1 | 1 |  |
Alpha subunit of glutamate synthase, C-terminal domain | alpha-helical ferredoxin | 1 | 1 |  |
Protein kinase-like (PK-like) | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 |  |
Trimeric LpxA-like enzymes | Heme-dependent catalase-like | 1 | 1 |  |
TolB, C-terminal domain | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 |  |
Protein kinase-like (PK-like) | BEACH domain | 1 | 1 |  |
Skp1 dimerisation domain-like | Skp1 dimerisation domain-like | 1 | 1 |  |
vWA-like | SAP domain | 1 | 1 |  |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | "Winged helix" DNA-binding domain | 1 | 1 |  |
DNA repair protein MutS, domain III | SMR domain-like | 1 | 1 |  |
Aquaporin-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
SSo0622-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
UBA-like | NSFL1 (p97 ATPase) cofactor p47, SEP domain | 1 | 1 |  |
Phage fibre proteins | Tricorn protease N-terminal domain | 1 | 1 |  |
Sec63 N-terminal domain-like | DNA/RNA polymerases | 1 | 1 |  |
RNI-like | alpha/beta-Hydrolases | 1 | 1 |  |
PA domain | RING/U-box | 1 | 1 |  |
SMI1/KNR4-like | ApaG-like | 1 | 1 |  |
UBC-like | Class II aaRS ABD-related | 1 | 1 |  |
Ankyrin repeat | Pseudo ankyrin repeat-like | 1 | 1 |  |
FYVE/PHD zinc finger | F-box domain | 1 | 1 |  |
NusB-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
SNARE-like | Domain of the SRP/SRP receptor G-proteins | 1 | 1 |  |
PLP-dependent transferases | Clavaminate synthase-like | 1 | 1 |  |
Adenine nucleotide alpha hydrolases-like | Molybdenum cofactor biosynthesis proteins | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | alpha/beta-Hydrolases | 1 | 1 |  |
gp5 N-terminal domain-like | Tricorn protease N-terminal domain | 1 | 1 |  |
L domain-like | Actin-crosslinking proteins | 1 | 1 |  |
Protein kinase-like (PK-like) | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 |  |
L domain-like | ARM repeat | 1 | 1 |  |
Multidrug resistance efflux transporter EmrE | ENTH/VHS domain | 1 | 1 |  |
Single hybrid motif | ClpP/crotonase | 1 | 1 |  |
FAD/NAD(P)-binding domain | 4Fe-4S ferredoxins | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Retrovirus zinc finger-like domains | 1 | 1 |  |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Zinc beta-ribbon | 1 | 1 |  |
Tudor/PWWP/MBT | DNA repair protein MutS, domain II | 1 | 1 |  |
Aconitase iron-sulfur domain | Oxysterol-binding protein-like | 1 | 1 |  |
Ubiquitin-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
alpha/beta-Hydrolases | Ankyrin repeat | 1 | 1 |  |
Glutamine synthetase/guanido kinase | GatB/YqeY motif | 1 | 1 |  |
PH domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 |  |
lambda repressor-like DNA-binding domains | Cyanase C-terminal domain | 1 | 1 |  |
FYSH domain | Hypothetical protein AF0491, middle domain | 1 | 1 |  |
CheY-like | DNA-binding domain | 1 | 1 |  |
beta-beta-alpha zinc fingers | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
GST C-terminal domain-like | Ribosomal protein L25-like | 1 | 1 |  |
Zn-dependent exopeptidases | Carboxypeptidase regulatory domain-like | 1 | 1 |  |
F-box domain | LysM domain | 1 | 1 |  |
"Winged helix" DNA-binding domain | HRDC-like | 1 | 1 |  |
Oxygen-evolving enhancer protein 3, | Cyclophilin-like | 1 | 1 |  |
C-terminal UvrC-binding domain of UvrB | ApaG-like | 1 | 1 |  |
"Winged helix" DNA-binding domain | NosL/MerB-like | 1 | 1 |  |
Cysteine proteinases | DNA-binding pseudobarrel domain | 1 | 1 |  |
Ribonuclease H-like | SH2 domain | 1 | 1 |  |
TolB, C-terminal domain | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
Toll/Interleukin receptor TIR domain | DNA-binding pseudobarrel domain | 1 | 1 |  |
Cullin repeat-like | WRKY DNA-binding domain | 1 | 1 |  |
Hypothetical protein AF0491, middle domain | beta-beta-alpha zinc fingers | 1 | 1 |  |
Fumarylacetoacetate hydrolase, FAH, N-terminal domain | FAH | 1 | 1 |  |
6-phosphogluconate dehydrogenase C-terminal domain-like | alpha/beta-Hydrolases | 1 | 1 |  |
TAF(II)230 TBP-binding fragment | Ubiquitin-like | 1 | 1 |  |
Sec1/munc18-like (SM) proteins | Sec1/munc18-like (SM) proteins | 1 | 1 |  |
beta-beta-alpha zinc fingers | CCCH zinc finger | 1 | 1 |  |
IlvD/EDD N-terminal domain-like | LeuD/IlvD-like | 1 | 1 |  |
WD40 repeat-like | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 |  |
TPR-like | Calcium-dependent phosphotriesterase | 1 | 1 |  |
RNI-like | beta and beta-prime subunits of DNA dependent RNA-polymerase | 1 | 1 |  |
Protein kinase-like (PK-like) | Class II aaRS and biotin synthetases | 1 | 1 |  |
C2 domain (Calcium/lipid-binding domain, CaLB) | MHC antigen-recognition domain | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Prismane protein-like | 1 | 1 |  |
Ribonuclease H-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
DNA breaking-rejoining enzymes | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 |  |
L domain-like | RING/U-box | 1 | 1 |  |
Nucleic acid-binding proteins | L domain-like | 1 | 1 |  |
ALDH-like | TPR-like | 1 | 1 |  |
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | Protein kinase-like (PK-like) | 1 | 1 |  |
TPR-like | FAD/NAD(P)-binding domain | 1 | 1 |  |
WD40 repeat-like | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 |  |
Terpenoid synthases | L domain-like | 1 | 1 |  |
ISP transmembrane anchor | ISP domain | 1 | 1 |  |
ARID-like | Homeodomain-like | 1 | 1 |  |
Chaperone J-domain | Multiheme cytochromes | 1 | 1 |  |
Starch-binding domain-like | Carboxypeptidase regulatory domain-like | 1 | 1 |  |
TK C-terminal domain-like | HAD-like | 1 | 1 |  |
MIT domain | MIT domain | 1 | 1 |  |
alpha/beta-Hydrolases | FAD/NAD(P)-binding domain | 1 | 1 |  |
ValRS/IleRS/LeuRS editing domain | tRNA-binding arm | 1 | 1 |  |
DAK1/DegV-like | DhaL-like | 1 | 1 |  |
EPT/RTPC-like | EPT/RTPC-like | 1 | 1 |  |
Thiamin diphosphate-binding fold (THDP-binding) | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
Cullin repeat-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 |  |
Rad51 N-terminal domain-like | ARM repeat | 1 | 1 |  |
Carbohydrate phosphatase | TK C-terminal domain-like | 1 | 1 |  |
FYVE/PHD zinc finger | Chromo domain-like | 1 | 1 |  |
Phosphofructokinase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 |  |
DNA repair protein MutS, domain I | GIY-YIG endonuclease | 1 | 1 |  |
Pectin lyase-like | RmlC-like cupins | 1 | 1 |  |
Phage tail proteins | alpha/beta-Hydrolases | 1 | 1 |  |
Nucleic acid-binding proteins | DNA-binding domain | 1 | 1 |  |
MHC antigen-recognition domain | Protein kinase-like (PK-like) | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | HAD-like | 1 | 1 |  |
HMG-box | Leucine zipper domain | 1 | 1 |  |
WGR domain-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
HD-domain/PDEase-like | ACT-like | 1 | 1 |  |
MHC antigen-recognition domain | ARM repeat | 1 | 1 |  |
SGNH hydrolase | SGNH hydrolase | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Cysteine proteinases | 1 | 1 |  |
Ran binding protein zinc finger-like | DNase I-like | 1 | 1 |  |
(Phosphotyrosine protein) phosphatases II | RNA-binding domain, RBD | 1 | 1 |  |
PLP-dependent transferases | MOSC N-terminal domain-like | 1 | 1 |  |
F-box domain | ApaG-like | 1 | 1 |  |
Rudiment single hybrid motif | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 |  |
Ribonuclease Rh-like | Ribonuclease Rh-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | Ribonuclease Rh-like | 1 | 1 |  |
FAD/NAD(P)-binding domain | Nucleic acid-binding proteins | 1 | 1 |  |
Phosphofructokinase | NAD(P)-binding Rossmann-fold domains | 1 | 1 |  |
WD40 repeat-like | Toll/Interleukin receptor TIR domain | 1 | 1 |  |
L domain-like | FabD/lysophospholipase-like | 1 | 1 |  |
Thioredoxin-like | Ribonuclease Rh-like | 1 | 1 |  |
P-loop containing nucleoside triphosphate hydrolases | SMR domain-like | 1 | 1 |  |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | tRNA-binding arm | 1 | 1 |  |
TPR-like | Phospholipase D/nuclease | 1 | 1 |  |
SAM/Pointed domain | Metallo-hydrolase/oxidoreductase | 1 | 1 |  |
F-box domain | Outer arm dynein light chain 1 | 1 | 1 |  |
SWIB/MDM2 domain | eIF1-like | 1 | 1 |  |
Periplasmic binding protein-like II | MetI-like | 1 | 1 |  |
HydA/Nqo6-like | Nqo5-like | 1 | 1 |  |
FAD-linked reductases, C-terminal domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 1 | 1 |  |
Kix domain of CBP (creb binding protein) | Kix domain of CBP (creb binding protein) | 1 | 1 |  |
Acetyl-CoA synthetase-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 |  |
GAF domain-like | Acetyl-CoA synthetase-like | 1 | 1 |  |
Carbohydrate phosphatase | Thiamin diphosphate-binding fold (THDP-binding) | 1 | 1 |  |
Cysteine-rich domain | Caspase-like | 1 | 1 |  |
Terpenoid synthases | Outer arm dynein light chain 1 | 1 | 1 |  |
Carbamate kinase-like | Carbamate kinase-like | 1 | 1 |  |
Cytochrome b5-like heme/steroid binding domain | alpha/beta-Hydrolases | 1 | 1 |  |
UBA-like | post-AAA+ oligomerization domain-like | 1 | 1 |  |
Rhodanese/Cell cycle control phosphatase | alpha/beta-Hydrolases | 1 | 1 |  |