Domain combination pairs in Nematostella vectensis 1.0

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

2334 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
EGF/Laminin	EGF/Laminin	220	100
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	190	48
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	136	53
Immunoglobulin	Immunoglobulin	120	61
Galactose-binding domain-like	Galactose-binding domain-like	98	22
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	91	3
EGF/Laminin	Growth factor receptor domain	89	66
TSP-1 type 1 repeat	TSP-1 type 1 repeat	86	25
TPR-like	TPR-like	83	28
Growth factor receptor domain	Growth factor receptor domain	64	47
RING/U-box	B-box zinc-binding domain	61	15
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	49	9
Cadherin-like	Cadherin-like	49	30
Voltage-gated potassium channels	Voltage-gated potassium channels	44	11
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	43	17
RNA-binding domain, RBD	RNA-binding domain, RBD	43	20
POZ domain	Voltage-gated potassium channels	43	5
Actin-like ATPase domain	Actin-like ATPase domain	41	11
ARM repeat	ARM repeat	40	24
POZ domain	Kelch motif	40	8
Spermadhesin, CUB domain	Spermadhesin, CUB domain	39	20
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	34	25
Immunoglobulin	Fibronectin type III	32	26
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	32	16
Fibronectin type III	Fibronectin type III	31	27
EF-hand	EF-hand	31	17
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	30	3
LDL receptor-like module	LDL receptor-like module	30	15
ABC transporter transmembrane region	ABC transporter transmembrane region	29	6
PH domain-like	DBL homology domain (DH-domain)	28	19
RING/U-box	TRAF domain-like	28	14
Concanavalin A-like lectins/glucanases	EGF/Laminin	27	24
SRCR-like	SRCR-like	27	9
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	27	11
Fibrinogen C-terminal domain-like	Hairpin loop containing domain-like	27	10
CalX-like	CalX-like	26	16
F-box domain	RNI-like	26	9
WD40 repeat-like	WD40 repeat-like	26	15
Homeodomain-like	Homeodomain-like	25	16
Thioredoxin-like	GST C-terminal domain-like	25	2
B-box zinc-binding domain	E set domains	25	12
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	23	10
Complement control module/SCR domain	Complement control module/SCR domain	22	16
Second domain of FERM	PH domain-like	21	13
RNI-like	RNI-like	21	8
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	21	10
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	21	2
Ubiquitin-like	Second domain of FERM	21	12
RING/U-box	RING/U-box	21	14
Ubiquitin-like	PH domain-like	21	13
HAD-like	Calcium ATPase, transmembrane domain M	20	6
Galactose-binding domain-like	EGF/Laminin	20	14
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	20	14
PH domain-like	PH domain-like	19	16
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	19	5
vWA-like	vWA-like	19	13
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	19	4
Calcium ATPase, transduction domain A	HAD-like	19	5
Voltage-gated potassium channels	cAMP-binding domain-like	19	9
Thioredoxin-like	Thioredoxin-like	19	11
Periplasmic binding protein-like II	Voltage-gated potassium channels	18	7
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	18	15
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	18	3
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	18	6
RING/U-box	E set domains	18	8
ARM repeat	Protein kinase-like (PK-like)	18	13
EGF/Laminin	Fibrinogen C-terminal domain-like	17	8
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	17	3
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	17	2
E set domains	NHL repeat	17	8
MFS general substrate transporter	MFS general substrate transporter	17	5
L domain-like	Family A G protein-coupled receptor-like	17	6
TRAF domain-like	TRAF domain-like	17	9
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	17	3
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	17	3
GroEL equatorial domain-like	GroEL apical domain-like	17	4
Thyroglobulin type-1 domain	Thyroglobulin type-1 domain	16	3
SH3-domain	SH3-domain	16	12
Spectrin repeat	Spectrin repeat	16	16
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	16	9
Actin depolymerizing proteins	Actin depolymerizing proteins	16	12
PDZ domain-like	PDZ domain-like	16	14
EGF/Laminin	Hairpin loop containing domain-like	16	11
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	16	6
PA domain	Zn-dependent exopeptidases	16	2
Cyclin-like	Cyclin-like	16	4
FYVE/PHD zinc finger	FYVE/PHD zinc finger	16	12
PGBD-like	Metalloproteases ("zincins"), catalytic domain	15	5
PA domain	Transferrin receptor-like dimerisation domain	15	1
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	15	10
B-box zinc-binding domain	NHL repeat	15	6
Cadherin-like	EGF/Laminin	15	11
Kelch motif	Kelch motif	15	8
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	14	6
RING/U-box	NHL repeat	14	5
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	14	5
SH3-domain	BAR/IMD domain-like	14	8
Thiolase-like	Thiolase-like	14	2
GroEL equatorial domain-like	GroEL-intermediate domain like	14	3
cAMP-binding domain-like	cAMP-binding domain-like	14	8
Family A G protein-coupled receptor-like	Family A G protein-coupled receptor-like	13	6
EGF/Laminin	YWTD domain	13	11
Tudor/PWWP/MBT	Tudor/PWWP/MBT	13	12
GroEL-intermediate domain like	GroEL apical domain-like	13	2
(Trans)glycosidases	Glycosyl hydrolase domain	13	6
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	13	4
GroES-like	NAD(P)-binding Rossmann-fold domains	13	1
SH3-domain	PH domain-like	12	12
Guanido kinase N-terminal domain	Glutamine synthetase/guanido kinase	12	4
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	12	10
Hairpin loop containing domain-like	Concanavalin A-like lectins/glucanases	12	5
Pentapeptide repeat-like	Pentapeptide repeat-like	12	7
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	12	12
Ubiquitin-like	Ubiquitin-like	12	11
C-type lectin-like	C-type lectin-like	11	8
E set domains	E set domains	11	10
F-box domain	WD40 repeat-like	11	6
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	11	5
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	11	10
Nucleic acid-binding proteins	Nucleic acid-binding proteins	11	10
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	11	3
(Trans)glycosidases	Galactose-binding domain-like	11	5
Protein kinase-like (PK-like)	Nucleotide cyclase	11	3
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	10	3
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	10	2
CoA-dependent acyltransferases	CoA-dependent acyltransferases	10	2
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	10	4
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	10	7
Histone-fold	Histone-fold	10	2
Fibronectin type III	Voltage-gated potassium channels	10	10
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	10	4
DEATH domain	P-loop containing nucleoside triphosphate hydrolases	10	10
PreATP-grasp domain	Rudiment single hybrid motif	10	7
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	10	5
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	10	5
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	9	4
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	9	9
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	9	7
lambda repressor-like DNA-binding domains	Homeodomain-like	9	2
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	9	5
PH domain-like	GTPase activation domain, GAP	9	8
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	9	4
Periplasmic binding protein-like I	Periplasmic binding protein-like II	9	7
P-loop containing nucleoside triphosphate hydrolases	TPR-like	9	7
WW domain	WW domain	9	8
Subtilisin-like	Galactose-binding domain-like	9	4
L domain-like	L domain-like	9	8
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	9	7
POZ domain	POZ domain	9	7
Protease propeptides/inhibitors	Subtilisin-like	9	4
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	9	6
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	8	2
UBA-like	Ubiquitin-like	8	8
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	8	7
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	8	6
Ribonuclease H-like	DNA/RNA polymerases	8	7
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	3
Concanavalin A-like lectins/glucanases	C-type lectin-like	8	7
EF-hand	PLC-like phosphodiesterases	8	8
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	8	5
TPR-like	HCP-like	8	8
SET domain	beta-beta-alpha zinc fingers	8	5
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	8	8
Concanavalin A-like lectins/glucanases	Fibronectin type III	8	7
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	8	6
LDL receptor-like module	YWTD domain	8	8
Concanavalin A-like lectins/glucanases	Metalloproteases ("zincins"), catalytic domain	8	2
RNI-like	EF-hand	8	4
PHM/PNGase F	PHM/PNGase F	8	3
Spermadhesin, CUB domain	EGF/Laminin	8	8
Hairpin loop containing domain-like	Galactose-binding domain-like	8	5
FYVE/PHD zinc finger	Bromodomain	8	6
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	8	2
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	8	3
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	8	8
MFS general substrate transporter	Kazal-type serine protease inhibitors	8	2
Calponin-homology domain, CH-domain	Spectrin repeat	8	8
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	7	6
SH3-domain	PDZ domain-like	7	7
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	7	4
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	7	2
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	7	4
Kazal-type serine protease inhibitors	EF-hand	7	5
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	7	4
DEATH domain	DEATH domain	7	7
WD40 repeat-like	RING/U-box	7	5
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	7	5
BRCT domain	BRCT domain	7	7
LDL receptor-like module	EGF/Laminin	7	7
Cysteine-rich domain	Cysteine-rich domain	7	6
PH domain-like	(Phosphotyrosine protein) phosphatases II	7	5
Cullin homology domain	"Winged helix" DNA-binding domain	7	3
Complement control module/SCR domain	EGF/Laminin	7	7
Fibronectin type III	TSP-1 type 1 repeat	7	7
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	7	5
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	7	3
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	7	4
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	7	4
vWA-like	EGF/Laminin	7	5
Insect cysteine-rich antifreeze protein	Insect cysteine-rich antifreeze protein	7	4
Galactose oxidase, central domain	Kelch motif	7	4
Periplasmic binding protein-like I	Growth factor receptor domain	7	3
Invertebrate chitin-binding proteins	Invertebrate chitin-binding proteins	7	7
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	7	3
Cadherin-like	Concanavalin A-like lectins/glucanases	7	7
Protease propeptides/inhibitors	Galactose-binding domain-like	7	2
PDZ domain-like	PH domain-like	6	6
Galactose-binding domain-like	Fibronectin type III	6	6
FAS1 domain	FAS1 domain	6	5
YWTD domain	Growth factor receptor domain	6	6
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	6	4
Growth factor receptor domain	Concanavalin A-like lectins/glucanases	6	6
PH domain-like	FYVE/PHD zinc finger	6	6
PreATP-grasp domain	Single hybrid motif	6	3
Rudiment single hybrid motif	Single hybrid motif	6	3
SH3-domain	DBL homology domain (DH-domain)	6	6
L27 domain	PDZ domain-like	6	6
BEACH domain	WD40 repeat-like	6	5
Ubiquitin-like	PDZ domain-like	6	6
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	6	6
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	3
ARM repeat	WD40 repeat-like	6	6
PAZ domain	Ribonuclease H-like	6	4
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	6	5
P-loop containing nucleoside triphosphate hydrolases	RNI-like	6	5
RING/U-box	Cysteine proteinases	6	5
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	6	6
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	6	1
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	6	4
PH domain-like	SH2 domain	6	4
Nucleotide cyclase	EAL domain-like	6	3
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	6	4
GAF domain-like	GAF domain-like	6	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	6	5
Cullin repeat-like	"Winged helix" DNA-binding domain	6	2
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	6	1
Ligand-binding domain in the NO signalling and Golgi transport	Nucleotide cyclase	6	2
Cysteine-rich domain	Protein kinase-like (PK-like)	6	5
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	3
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	6	5
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	6	3
dsRNA-binding domain-like	dsRNA-binding domain-like	6	6
PKD domain	PKD domain	6	6
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	6	3
Cullin repeat-like	Cullin homology domain	6	2
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	6	2
PH domain-like	ArfGap/RecO-like zinc finger	6	6
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	6	5
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	6	5
POZ domain	Galactose oxidase, central domain	6	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	6	3
L domain-like	Growth factor receptor domain	6	5
Galactose-binding domain-like	Growth factor receptor domain	5	5
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	5	1
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	5	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	5	3
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	5	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	5	5
Concanavalin A-like lectins/glucanases	Spermadhesin, CUB domain	5	5
CHY zinc finger-like	Zinc hairpin stack	5	5
Spectrin repeat	EF-hand	5	5
t-snare proteins	SNARE fusion complex	5	3
Cysteine-rich domain	C2 domain (Calcium/lipid-binding domain, CaLB)	5	4
Voltage-gated potassium channels	E set domains	5	3
DEATH domain	Caspase-like	5	4
vWA-like	Integrin domains	5	3
Galactose-binding domain-like	C-type lectin-like	5	5
Ankyrin repeat	ARM repeat	5	5
PH domain-like	BEACH domain	5	3
DEATH domain	TPR-like	5	5
Plexin repeat	vWA-like	5	3
Ubiquitin-like	Cysteine proteinases	5	4
Protease propeptides/inhibitors	Zn-dependent exopeptidases	5	2
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	5	3
(Trans)glycosidases	Chitinase insertion domain	5	1
Spermadhesin, CUB domain	Growth factor receptor domain	5	5
LDL receptor-like module	Growth factor receptor domain	5	5
Concanavalin A-like lectins/glucanases	Galactose-binding domain-like	5	5
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	5
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	5	5
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	5	3
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	5	5
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	5	4
SAM/Pointed domain	SAM/Pointed domain	5	4
PH domain-like	PLC-like phosphodiesterases	5	5
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	5	5
DUSP-like	Cysteine proteinases	5	5
Integrin domains	EGF/Laminin	5	3
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	5	2
PH domain-like	EF-hand	5	5
Fibronectin type III	Protein kinase-like (PK-like)	5	5
PX domain	BAR/IMD domain-like	5	2
Plexin repeat	Integrin domains	5	3
Translation proteins	EF-G C-terminal domain-like	5	4
Flavoproteins	Riboflavin synthase domain-like	5	4
FYVE/PHD zinc finger	DNase I-like	5	3
"Winged helix" DNA-binding domain	Periplasmic binding protein-like II	5	1
Complement control module/SCR domain	Growth factor receptor domain	5	5
PH domain-like	Cysteine-rich domain	5	5
WD40 repeat-like	SOCS box-like	5	3
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	2
HMG-box	HMG-box	5	3
GAF domain-like	HD-domain/PDEase-like	5	3
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	5
Plexin repeat	EGF/Laminin	5	3
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	5	3
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	5	4
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	5
Fibrinogen C-terminal domain-like	Fibrinogen C-terminal domain-like	5	3
L27 domain	P-loop containing nucleoside triphosphate hydrolases	4	4
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	4	4
SH2 domain	SOCS box-like	4	1
DNase I-like	DNase I-like	4	4
Sec7 domain	PH domain-like	4	3
Doublecortin (DC)	Doublecortin (DC)	4	4
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	4	4
EF-hand	Cysteine proteinases	4	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	4	2
PH domain-like	Ankyrin repeat	4	4
L27 domain	SH3-domain	4	4
Restriction endonuclease-like	FYVE/PHD zinc finger	4	3
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	3
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	4	4
Cytochrome b5-like heme/steroid binding domain	Oxidoreductase molybdopterin-binding domain	4	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	4	4
Complement control module/SCR domain	Concanavalin A-like lectins/glucanases	4	4
SNARE-like	SNARE fusion complex	4	2
BAR/IMD domain-like	PH domain-like	4	4
YWTD domain	YWTD domain	4	4
CCCH zinc finger	RING/U-box	4	4
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	4	1
TB module/8-cys domain	EGF/Laminin	4	4
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	4	4
(Trans)glycosidases	E set domains	4	4
GINS helical bundle-like	PriA/YqbF domain	4	2
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	4	4
TSP-1 type 1 repeat	Voltage-gated potassium channels	4	4
TPR-like	"Winged helix" DNA-binding domain	4	1
PX domain	SH3-domain	4	3
Phage fibre proteins	Phage fibre proteins	4	3
Ubiquitin-like	Thioredoxin-like	4	4
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	4	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	4	4
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	4	4
FYVE/PHD zinc finger	Clavaminate synthase-like	4	4
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	4	3
Ankyrin repeat	Ankyrin repeat	4	4
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	4	2
FAD/NAD(P)-binding domain	Folate-binding domain	4	2
Pectin lyase-like	Pectin lyase-like	4	4
PH domain-like	ARM repeat	4	4
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	4	1
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	4
WD40 repeat-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	4	4
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	4	4
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	4	4
Galactose-binding domain-like	Immunoglobulin	4	4
RING/U-box	Concanavalin A-like lectins/glucanases	4	3
Ubiquitin-like	Protein kinase-like (PK-like)	4	4
ARM repeat	"Winged helix" DNA-binding domain	4	1
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	4	3
Cysteine proteinases	FYVE/PHD zinc finger	4	3
TPR-like	RING/U-box	4	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
Chromo domain-like	Chromo domain-like	4	3
PH domain-like	Ras GEF	4	4
Frizzled cysteine-rich domain	Frizzled cysteine-rich domain	4	3
Protein kinase-like (PK-like)	SH3-domain	4	4
Spectrin repeat	PH domain-like	4	4
FAD-linked reductases, C-terminal domain	Folate-binding domain	4	2
FAD-linked reductases, C-terminal domain	Aminomethyltransferase beta-barrel domain	4	2
Cytochrome b5-like heme/steroid binding domain	E set domains	4	2
PH domain-like	WD40 repeat-like	4	3
Kringle-like	Kringle-like	4	1
ARM repeat	Formin homology 2 domain (FH2 domain)	4	3
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	4	4
SH3-domain	SH2 domain	4	4
BAR/IMD domain-like	GTPase activation domain, GAP	4	4
TSP type-3 repeat	Concanavalin A-like lectins/glucanases	4	4
Chondroitin AC/alginate lyase	Galactose mutarotase-like	4	3
Ankyrin repeat	SH3-domain	4	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	4	4
SMAD MH1 domain	SMAD/FHA domain	4	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	3
Ankyrin repeat	POZ domain	4	4
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	4	2
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	4
Somatomedin B domain	Family A G protein-coupled receptor-like	4	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	3
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	2
PR-1-like	PR-1-like	4	4
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	4	3
TSP type-3 repeat	TSP type-3 repeat	4	4
EF-hand	Mitochondrial carrier	4	2
Ubiquitin-like	ARM repeat	4	3
ClpP/crotonase	ClpP/crotonase	4	2
Immunoglobulin	Protein kinase-like (PK-like)	4	3
Nucleotide cyclase	Nucleotide cyclase	4	3
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	4	4
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	4	2
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	4	3
Periplasmic binding protein-like I	Periplasmic binding protein-like I	4	4
Hairpin loop containing domain-like	Hairpin loop containing domain-like	4	4
Translation proteins	Ribosomal protein S5 domain 2-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	3
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	4	4
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipase/lipooxygenase domain (PLAT/LH2 domain)	4	3
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	4	4
EF-hand	WD40 repeat-like	4	4
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	4	3
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	4	2
Oxidoreductase molybdopterin-binding domain	E set domains	4	2
FAD/NAD(P)-binding domain	Aminomethyltransferase beta-barrel domain	4	2
Snake toxin-like	Protein kinase-like (PK-like)	4	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
Protein kinase-like (PK-like)	SAM/Pointed domain	4	3
UBA-like	RING/U-box	4	4
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	4	4
Adhesin YadA, collagen-binding domain	Adhesin YadA, collagen-binding domain	4	1
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	4	4
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	4	4
Clc chloride channel	CBS-domain pair	4	4
TPR-like	ARM repeat	3	3
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	3	2
Cysteine-rich domain	Ubiquitin-like	3	3
Nucleotide-binding domain	Nucleotide-binding domain	3	2
Plexin repeat	Integrin beta tail domain	3	2
PurM N-terminal domain-like	PurM C-terminal domain-like	3	3
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	3	1
Calponin-homology domain, CH-domain	EF-hand	3	3
PreATP-grasp domain	Aldolase	3	1
Calponin-homology domain, CH-domain	E set domains	3	3
Concanavalin A-like lectins/glucanases	SRCR-like	3	3
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	3	3
Regulator of G-protein signaling, RGS	PX domain	3	2
Zn-finger domain of Sec23/24	vWA-like	3	3
Sec63 N-terminal domain-like	E set domains	3	2
Cytidine deaminase-like	Cytidine deaminase-like	3	2
Cysteine-rich domain	GTPase activation domain, GAP	3	3
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
HIT/MYND zinc finger-like	SET domain	3	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	3	3
FKBP-like	TPR-like	3	3
Cap-Gly domain	Cysteine proteinases	3	2
vWA-like	Helical domain of Sec23/24	3	3
PreATP-grasp domain	post-HMGL domain-like	3	1
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	3	1
WD40 repeat-like	FYVE/PHD zinc finger	3	2
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	3	3
Formyltransferase	FMT C-terminal domain-like	3	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	3	2
Rudiment single hybrid motif	Aldolase	3	1
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	3	1
Galactose mutarotase-like	Glycosyl hydrolase domain	3	1
CCCH zinc finger	CCCH zinc finger	3	3
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	3	1
UBC-like	RING/U-box	3	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	3	3
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	3	3
Homeodomain-like	RING/U-box	3	3
Growth factor receptor domain	SEA domain	3	2
Calpain large subunit, middle domain (domain III)	EF-hand	3	1
CHY zinc finger-like	RING/U-box	3	3
FnI-like domain	FnI-like domain	3	3
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	3	3
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	3	3
Zinc hairpin stack	RING/U-box	3	3
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
EGF/Laminin	Integrin beta tail domain	3	2
Ubiquitin-like	RING/U-box	3	3
Ribonuclease H-like	RuvA domain 2-like	3	3
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	3	1
alpha/beta-Hydrolases	Galactose-binding domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	3	3
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	3	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	3	1
Translation proteins SH3-like domain	Nucleic acid-binding proteins	3	2
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	3	1
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	3	2
TPR-like	Clavaminate synthase-like	3	2
ARM repeat	Clathrin adaptor appendage domain	3	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Nucleotidyltransferase substrate binding subunit/domain	3	3
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	3
WD40 repeat-like	TPR-like	3	3
SAM/Pointed domain	RING/U-box	3	3
Saposin	Saposin	3	2
GTPase activation domain, GAP	SH3-domain	3	3
PreATP-grasp domain	Methylglyoxal synthase-like	3	3
Complement control module/SCR domain	vWA-like	3	3
Elafin-like	Elafin-like	3	3
Rudiment single hybrid motif	post-HMGL domain-like	3	1
TPR-like	HIT/MYND zinc finger-like	3	3
Protein kinase-like (PK-like)	DEATH domain	3	3
vWA-like	Integrin beta tail domain	3	2
Bromodomain	Bromodomain	3	3
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	3	3
"Winged helix" DNA-binding domain	FYVE/PHD zinc finger	3	3
Ribonuclease H-like	Ribonuclease H-like	3	2
post-HMGL domain-like	Single hybrid motif	3	1
Zinc beta-ribbon	Cyclin-like	3	3
Galactose-binding domain-like	Hect, E3 ligase catalytic domain	3	3
Galactose-binding domain-like	SEA domain	3	3
Concanavalin A-like lectins/glucanases	SEA domain	3	3
ARM repeat	Concanavalin A-like lectins/glucanases	3	3
ENTH/VHS domain	GAT-like domain	3	2
RING/U-box	Fibronectin type III	3	2
RCC1/BLIP-II	RCC1/BLIP-II	3	3
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	3	2
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	2
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	3
Translation proteins	Translation proteins	3	2
Amine oxidase N-terminal region	Amine oxidase N-terminal region	3	2
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	3	3
RCC1/BLIP-II	Protein kinase-like (PK-like)	3	2
B-box zinc-binding domain	Fibronectin type III	3	2
Aldolase	Single hybrid motif	3	1
PH domain-like	Oxysterol-binding protein-like	3	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	2
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	3	2
FYVE/PHD zinc finger	Tudor/PWWP/MBT	3	3
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	3	1
Single hybrid motif	CoA-dependent acyltransferases	3	1
Aldolase	post-HMGL domain-like	3	1
FYVE/PHD zinc finger	RING/U-box	3	3
Translation proteins	Initiation factor IF2/eIF5b, domain 3	3	2
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	3	3
Aconitase iron-sulfur domain	LeuD/IlvD-like	3	1
E set domains	Cysteine proteinases	3	2
Thiolase-like	FabD/lysophospholipase-like	3	1
RING/U-box	Calcium-dependent phosphotriesterase	3	3
beta-sandwich domain of Sec23/24	vWA-like	3	3
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	3
Ubiquitin-like	Ras GEF	3	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
P-loop containing nucleoside triphosphate hydrolases	POZ domain	3	1
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	3	2
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	3	3
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	3	3
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	2
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	3	1
EGF/Laminin	C-type lectin-like	3	3
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	3	3
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	Multidrug efflux transporter AcrB transmembrane domain	3	2
MgtE N-terminal domain-like	MgtE N-terminal domain-like	3	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	3	3
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	3	2
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	3	3
RING/U-box	PUA domain-like	3	3
SNF-like	SNF-like	3	1
L domain-like	Immunoglobulin	3	3
Immunoglobulin	Family A G protein-coupled receptor-like	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	2
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	3	2
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	3	3
Ubiquitin-like	Ankyrin repeat	3	3
Guanido kinase N-terminal domain	Guanido kinase N-terminal domain	3	2
SEA domain	Fibronectin type III	3	3
Amine oxidase N-terminal region	Amine oxidase catalytic domain	3	2
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	3	2
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	3	1
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	3	3
UBA-like	UBA-like	3	3
Toll/Interleukin receptor TIR domain	SAM/Pointed domain	3	2
vWA-like	Concanavalin A-like lectins/glucanases	3	3
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	3	2
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	2
Integrin domains	Integrin beta tail domain	3	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	3	3
Glutathione synthetase ATP-binding domain-like	Aldolase	3	1
TSP-1 type 1 repeat	EGF/Laminin	3	3
Immunoglobulin	Spermadhesin, CUB domain	3	3
ARM repeat	Cysteine proteinases	3	3
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
EF-hand	RING/U-box	3	3
Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	3	2
beta-N-acetylhexosaminidase-like domain	E set domains	3	3
Protein kinase-like (PK-like)	Polo-box domain	3	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	3	3
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	3	3
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	3	1
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	3	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	3	1
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	3	2
Galactose-binding domain-like	vWA-like	3	3
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	3	3
Nucleotidylyl transferase	P-loop containing nucleoside triphosphate hydrolases	3	3
ArfGap/RecO-like zinc finger	Ankyrin repeat	3	3
PGBD-like	Hemopexin-like domain	3	2
Immunoglobulin	Complement control module/SCR domain	3	3
Galactose-binding domain-like	Protein kinase-like (PK-like)	3	3
SGNH hydrolase	DNase I-like	3	2
p53-like transcription factors	E set domains	3	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	3	2
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	3	3
SNARE fusion complex	SNARE fusion complex	3	2
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	3	3
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	3	1
FKBP-like	EF-hand	3	1
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	3	1
Galactose mutarotase-like	(Trans)glycosidases	3	1
ADC-like	Cdc48 domain 2-like	2	1
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	2	2
Galactose-binding domain-like	Spermadhesin, CUB domain	2	2
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
WD40 repeat-like	NHL repeat	2	2
Cap-Gly domain	Cap-Gly domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	2	1
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	2	2
Immunoglobulin	tRNA-intron endonuclease catalytic domain-like	2	2
MIR domain	MIR domain	2	2
Taf5 N-terminal domain-like	WD40 repeat-like	2	2
B-box zinc-binding domain	Concanavalin A-like lectins/glucanases	2	1
WW domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	2
A DNA-binding domain in eukaryotic transcription factors	Leucine zipper domain	2	2
Homodimeric domain of signal transducing histidine kinase	CheY-like	2	2
L domain-like	RNI-like	2	2
P-loop containing nucleoside triphosphate hydrolases	R3H domain	2	2
PH domain-like	Moesin tail domain	2	1
SRCR-like	Growth factor receptor domain	2	2
Galactose-binding domain-like	Chondroitin AC/alginate lyase	2	2
Methylglyoxal synthase-like	Cytidine deaminase-like	2	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	2	2
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	2	1
Hedgehog/DD-peptidase	Hedgehog/intein (Hint) domain	2	1
Concanavalin A-like lectins/glucanases	LDL receptor-like module	2	2
L domain-like	RNA-binding domain, RBD	2	2
Tex N-terminal region-like	Nucleic acid-binding proteins	2	2
C-type lectin-like	Family A G protein-coupled receptor-like	2	1
SRCR-like	L domain-like	2	2
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	2
TB module/8-cys domain	TB module/8-cys domain	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
Immunoglobulin	C-type lectin-like	2	2
WW domain	Hect, E3 ligase catalytic domain	2	2
Growth factor receptor domain	Cadherin-like	2	2
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	2	2
Phage tail proteins	Phage tail proteins	2	2
RNA-binding domain, RBD	UBA-like	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	2
LDL receptor-like module	Spermadhesin, CUB domain	2	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	2
Calponin-homology domain, CH-domain	PH domain-like	2	2
Carbamate kinase-like	ALDH-like	2	1
PABC (PABP) domain	PABC (PABP) domain	2	2
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
WW domain	EF-hand	2	2
Growth factor receptor domain	Fibrinogen C-terminal domain-like	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
Thyroglobulin type-1 domain	EF-hand	2	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	1
P-loop containing nucleoside triphosphate hydrolases	E set domains	2	1
TATA-box binding protein-like	DNA-glycosylase	2	1
Mitochondrial carrier	Pentapeptide repeat-like	2	2
Class I glutamine amidotransferase-like	PreATP-grasp domain	2	2
HlyD-like secretion proteins	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	2	2
Protein kinase-like (PK-like)	NTF2-like	2	1
SAP domain	Restriction endonuclease-like	2	1
EGF/Laminin	Fibronectin type III	2	2
NAD(P)-binding Rossmann-fold domains	SCP-like	2	2
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	2	2
CheY-like	P-loop containing nucleoside triphosphate hydrolases	2	2
BRCT domain	Homeodomain-like	2	2
FLJ32549 domain-like	FLJ32549 domain-like	2	1
Ubiquitin-like	DBL homology domain (DH-domain)	2	2
Trypsin-like serine proteases	PDZ domain-like	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	2	2
ADC-like	P-loop containing nucleoside triphosphate hydrolases	2	1
RUN domain-like	Ypt/Rab-GAP domain of gyp1p	2	2
cAMP-binding domain-like	Ras GEF	2	2
Cysteine proteinases	Cysteine proteinases	2	2
Thioredoxin-like	beta-beta-alpha zinc fingers	2	2
Cytokine	Cytokine	2	2
POZ domain	TRAF domain-like	2	2
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	2	2
PreATP-grasp domain	Composite domain of metallo-dependent hydrolases	2	2
Sec7 domain	ARM repeat	2	2
DBL homology domain (DH-domain)	GTPase activation domain, GAP	2	2
RCC1/BLIP-II	POZ domain	2	2
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	2	1
CAD & PB1 domains	UBA-like	2	2
Methyl-accepting chemotaxis protein (MCP) signaling domain	Methyl-accepting chemotaxis protein (MCP) signaling domain	2	2
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	2	1
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	1
CAD & PB1 domains	RING/U-box	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Carbohydrate-binding domain	E set domains	2	2
Second domain of FERM	Moesin tail domain	2	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	2	2
Spectrin repeat	DBL homology domain (DH-domain)	2	2
SH2 domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Globin-like	Globin-like	2	2
"Winged helix" DNA-binding domain	E set domains	2	1
Calponin-homology domain, CH-domain	GAS2 domain-like	2	1
B-box zinc-binding domain	Calcium-dependent phosphotriesterase	2	2
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	1
Barwin-like endoglucanases	Invertebrate chitin-binding proteins	2	2
Cysteine proteinases	UBA-like	2	2
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	2
Complement control module/SCR domain	Trypsin-like serine proteases	2	2
FYVE/PHD zinc finger	Family A G protein-coupled receptor-like	2	2
Glutathione synthetase ATP-binding domain-like	Composite domain of metallo-dependent hydrolases	2	2
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	2	2
CBD9-like	PHM/PNGase F	2	1
Protein kinase-like (PK-like)	KA1-like	2	2
Galactose-binding domain-like	Kringle-like	2	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	2	1
EGF/Laminin	Immunoglobulin	2	2
Voltage-gated potassium channels	EF-hand	2	2
Ankyrin repeat	RING/U-box	2	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	2	1
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
Mib/herc2 domain-like	RING/U-box	2	2
BAR/IMD domain-like	Cysteine-rich domain	2	2
Translation proteins	ThrRS/AlaRS common domain	2	2
Second domain of FERM	Second domain of FERM	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	2	2
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	2	1
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	2	1
Mib/herc2 domain-like	Galactose-binding domain-like	2	2
Immunoglobulin	Toll/Interleukin receptor TIR domain	2	2
L domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Homeodomain-like	FAD/NAD(P)-binding domain	2	2
ALDH-like	ALDH-like	2	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	2	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	2	2
Galactose-binding domain-like	Complement control module/SCR domain	2	2
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
alpha-helical ferredoxin	FMN-linked oxidoreductases	2	2
Ubiquitin-like	Moesin tail domain	2	1
PDZ domain-like	"Winged helix" DNA-binding domain	2	2
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	2	2
Cyclophilin-like	RNA-binding domain, RBD	2	2
PDZ domain-like	Second domain of FERM	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	2	2
PreATP-grasp domain	Metallo-dependent hydrolases	2	2
Tropomyosin	Tropomyosin	2	2
R3H domain	Ribonuclease H-like	2	2
Metalloproteases ("zincins"), catalytic domain	Fibronectin type III	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	1
Ubiquitin-like	RNI-like	2	2
Granulin repeat	Granulin repeat	2	2
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	2	1
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
TSP-1 type 1 repeat	Galactose-binding domain-like	2	2
ARM repeat	Toll/Interleukin receptor TIR domain	2	2
Nucleotide-binding domain	FMN-linked oxidoreductases	2	2
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	2	2
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	2	1
Acetyl-CoA synthetase-like	ACP-like	2	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	2	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	2	2
Integrin domains	Integrin domains	2	2
SMAD/FHA domain	SMAD/FHA domain	2	2
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	1
Homeodomain-like	FAD-linked reductases, C-terminal domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	2	2
CheY-like	C-terminal effector domain of the bipartite response regulators	2	1
Carbohydrate-binding domain	(Trans)glycosidases	2	2
PDZ domain-like	WW domain	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	2
Kelch motif	EGF/Laminin	2	2
Tex N-terminal region-like	Ribonuclease H-like	2	2
Ribonuclease H-like	Nucleic acid-binding proteins	2	2
PX domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Ankyrin repeat	SAM/Pointed domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
GTPase activation domain, GAP	RGC domain-like	2	2
Mib/herc2 domain-like	Hect, E3 ligase catalytic domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	1
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	2	2
SAM/Pointed domain	PH domain-like	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	2	2
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
F-box domain	L domain-like	2	2
Methylglyoxal synthase-like	Metallo-dependent hydrolases	2	2
DEATH domain	Toll/Interleukin receptor TIR domain	2	2
HMA, heavy metal-associated domain	HAD-like	2	2
Class I glutamine amidotransferase-like	P-loop containing nucleoside triphosphate hydrolases	2	2
EF-hand	Cysteine-rich domain	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	2	2
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	2	2
Myosin rod fragments	Myosin rod fragments	2	2
SAM/Pointed domain	HD-domain/PDEase-like	2	2
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	2	1
EGF/Laminin	Lipase/lipooxygenase domain (PLAT/LH2 domain)	2	2
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	2	2
PX domain	Outer arm dynein light chain 1	2	1
lambda integrase-like, N-terminal domain	DNA breaking-rejoining enzymes	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
C-type lectin-like	SEA domain	2	2
Barwin-like endoglucanases	Barwin-like endoglucanases	2	2
CRAL/TRIO domain	DBL homology domain (DH-domain)	2	2
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	2	2
EF-hand	SH3-domain	2	2
MIR domain	IP3 receptor type 1 binding core, domain 2	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
CalX-like	Concanavalin A-like lectins/glucanases	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	2	2
Chaperone J-domain	Homeodomain-like	2	1
beta-lactamase/transpeptidase-like	beta-lactamase/transpeptidase-like	2	2
TPR-like	SET domain	2	2
Tropomyosin	P-loop containing nucleoside triphosphate hydrolases	2	2
L domain-like	ARM repeat	2	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	2	2
WGR domain-like	ADP-ribosylation	2	2
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	2	1
PLP-binding barrel	Alanine racemase C-terminal domain-like	2	1
Chaperone J-domain	RNA-binding domain, RBD	2	2
RNase III domain-like	dsRNA-binding domain-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	2
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	2	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	2	2
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	2	2
WD40 repeat-like	Cyclophilin-like	2	1
ARM repeat	Hect, E3 ligase catalytic domain	2	2
TB module/8-cys domain	Growth factor receptor domain	2	2
MurCD N-terminal domain	MurD-like peptide ligases, catalytic domain	2	2
Phosphoenolpyruvate/pyruvate domain	Thioesterase/thiol ester dehydrase-isomerase	2	2
TRAF domain-like	WD40 repeat-like	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
PH domain-like	"Winged helix" DNA-binding domain	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
F-box domain	Pectin lyase-like	2	2
Protein kinase-like (PK-like)	UBA-like	2	2
cAMP-binding domain-like	"Winged helix" DNA-binding domain	2	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	2	2
WWE domain	Hect, E3 ligase catalytic domain	2	2
Frizzled cysteine-rich domain	TIMP-like	2	1
Carbamoyl phosphate synthetase, large subunit connection domain	Composite domain of metallo-dependent hydrolases	2	2
Zinc beta-ribbon	Zinc beta-ribbon	2	1
Concanavalin A-like lectins/glucanases	TSP-1 type 1 repeat	2	2
RuvA domain 2-like	Nucleic acid-binding proteins	2	2
CRAL/TRIO domain	Spectrin repeat	2	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Galactose-binding domain-like	Galactose mutarotase-like	2	2
Periplasmic binding protein-like II	MetI-like	2	2
Restriction endonuclease-like	Cysteine proteinases	2	1
Family A G protein-coupled receptor-like	alpha/beta-Hydrolases	2	2
RNA-binding domain, RBD	dsRNA-binding domain-like	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	2	2
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	2	2
CAD & PB1 domains	Protein kinase-like (PK-like)	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
Chaperone J-domain	Thioredoxin-like	2	2
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex, superhelical domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	2	1
EGF/Laminin	FAS1 domain	2	2
Immunoglobulin	Caspase-like	2	2
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	2	2
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	2	2
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	2	2
Polo-box domain	Polo-box domain	2	1
Tex N-terminal region-like	RuvA domain 2-like	2	2
Ankyrin repeat	Ras GEF	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	2	2
DBL homology domain (DH-domain)	WD40 repeat-like	2	2
ARID-like	Clavaminate synthase-like	2	2
PH domain-like	RUN domain-like	2	2
E set domains	Calcium-dependent phosphotriesterase	2	2
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	2	2
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	2	2
Phospholipase D/nuclease	Phospholipase D/nuclease	2	2
CRAL/TRIO domain	PH domain-like	2	2
C-type lectin-like	Hairpin loop containing domain-like	2	2
F-box domain	Sec7 domain	2	1
PX domain	Protein kinase-like (PK-like)	2	2
SH3-domain	Spectrin repeat	2	2
F-box domain	Concanavalin A-like lectins/glucanases	2	2
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	2	2
Methylglyoxal synthase-like	Composite domain of metallo-dependent hydrolases	2	2
TNF receptor-like	DEATH domain	2	1
RuvA domain 2-like	RuvA domain 2-like	2	2
Ubiquitin-like	Ran binding protein zinc finger-like	2	2
Ubiquitin-like	"Winged helix" DNA-binding domain	2	2
DEATH domain	Immunoglobulin	2	2
PsbU/PolX domain-like	Nucleotidyltransferase	2	2
Protein kinase-like (PK-like)	MIT domain	2	2
UBA-like	UBC-like	2	2
Glutaminase/Asparaginase	Ankyrin repeat	2	1
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
Carbohydrate-binding domain	beta-N-acetylhexosaminidase-like domain	2	2
Tropomyosin	Smc hinge domain	2	2
UBA-like	Hect, E3 ligase catalytic domain	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	2
P-loop containing nucleoside triphosphate hydrolases	CarD-like	2	2
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
Immunoglobulin	DNase I-like	2	2
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
Concanavalin A-like lectins/glucanases	Voltage-gated potassium channels	2	2
Second domain of FERM	RING/U-box	2	2
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	2	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	2
Ubiquitin-like	SH2 domain	2	2
cAMP-binding domain-like	Ubiquitin-like	2	2
Ankyrin repeat	Protein kinase-like (PK-like)	2	2
Integrin alpha N-terminal domain	Integrin domains	2	2
Concanavalin A-like lectins/glucanases	Immunoglobulin	2	2
Cadherin-like	Dystroglycan, domain 2	2	2
PH domain-like	Protein kinase-like (PK-like)	2	2
Metallo-dependent phosphatases	Metallo-dependent phosphatases	2	1
Translational machinery components	L30e-like	2	2
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	2	2
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	2	2
Nucleic acid-binding proteins	TPR-like	2	2
Galactose oxidase, central domain	Galactose oxidase, central domain	2	2
B-box zinc-binding domain	P-loop containing nucleoside triphosphate hydrolases	2	1
E set domains	Pectin lyase-like	2	2
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	2	2
Kringle-like	Protein kinase-like (PK-like)	2	2
Immunoglobulin	TSP-1 type 1 repeat	2	2
Trefoil	Trefoil	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	2	2
Spermadhesin, CUB domain	Kelch motif	2	2
(Trans)glycosidases	EGF/Laminin	2	2
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	2	2
Growth factor receptor domain	Mannose 6-phosphate receptor domain	2	2
EGF/Laminin	Trypsin-like serine proteases	2	2
Growth factor receptor domain	Fibronectin type III	2	2
DNase I-like	Family A G protein-coupled receptor-like	2	2
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	2	2
Sema domain	Plexin repeat	2	2
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	FabD/lysophospholipase-like	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
SH2 domain	GTPase activation domain, GAP	2	2
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	2
HCP-like	HCP-like	2	2
NHL repeat	BPTI-like	1	1
RUN domain-like	PDZ domain-like	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
Adenine nucleotide alpha hydrolases-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
TRAF domain-like	Trimerization domain of TRAF	1	1
His-Me finger endonucleases	DNA/RNA polymerases	1	1
PurM C-terminal domain-like	Formyltransferase	1	1
HIT/MYND zinc finger-like	HIT/MYND zinc finger-like	1	1
PYP-like sensor domain (PAS domain)	CheY-like	1	1
PDZ domain-like	EF-hand	1	1
WD40 repeat-like	Chromo domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
Ubiquitin-like	PX domain	1	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Methenyltetrahydrofolate cyclohydrolase-like	1	1
GTPase activation domain, GAP	ARM repeat	1	1
Thioredoxin-like	NHL repeat	1	1
POZ domain	Pentapeptide repeat-like	1	1
Metalloproteases ("zincins"), catalytic domain	C-type lectin-like	1	1
TRAF domain-like	Cysteine proteinases	1	1
"Winged helix" DNA-binding domain	GroEL apical domain-like	1	1
TSP-1 type 1 repeat	Spermadhesin, CUB domain	1	1
PAH2 domain	PAH2 domain	1	1
Quinoprotein alcohol dehydrogenase-like	Ypt/Rab-GAP domain of gyp1p	1	1
PurM N-terminal domain-like	Formyltransferase	1	1
TPR-like	Tropomyosin	1	1
GST C-terminal domain-like	GST C-terminal domain-like	1	1
Dcp2 domain-like	Nudix	1	1
RNA-binding domain, RBD	GYF domain	1	1
Composite domain of metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
Nucleotide cyclase	Metallo-dependent hydrolases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
vWA-like	Cysteine-rich domain	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
STAT	SH2 domain	1	1
alpha/beta-Hydrolases	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
TIMP-like	Concanavalin A-like lectins/glucanases	1	1
Tubby C-terminal domain-like	Ribonuclease H-like	1	1
Immunoglobulin	Frizzled cysteine-rich domain	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
PP2C-like	Protein serine/threonine phosphatase 2C, C-terminal domain	1	1
RNA-binding domain, RBD	RNI-like	1	1
RNA-binding domain, RBD	PAP/OAS1 substrate-binding domain	1	1
SAICAR synthase-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
PH domain-like	RING/U-box	1	1
SAP domain	SAP domain	1	1
Methylated DNA-protein cysteine methyltransferase domain	Methylated DNA-protein cysteine methyltransferase, C-terminal domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Ribokinase-like	1	1
Periplasmic binding protein-like I	Nucleotide cyclase	1	1
Fibronectin type III	Periplasmic binding protein-like II	1	1
"Winged helix" DNA-binding domain	SAICAR synthase-like	1	1
CSL zinc finger	Chaperone J-domain	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
His-Me finger endonucleases	Ribonuclease H-like	1	1
Ribonuclease H-like	MFS general substrate transporter	1	1
RuvA domain 2-like	Pentapeptide repeat-like	1	1
DNA/RNA polymerases	Zinc finger domain of DNA polymerase-alpha	1	1
Transglutaminase, two C-terminal domains	Transglutaminase, two C-terminal domains	1	1
BRK domain-like	Bromodomain	1	1
PH domain-like	Regulator of G-protein signaling, RGS	1	1
Thioredoxin-like	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
Seven-hairpin glycosidases	Seven-hairpin glycosidases	1	1
PLP-dependent transferases	Rudiment single hybrid motif	1	1
Pentein	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
E set domains	Glycosyl hydrolase domain	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
IP3 receptor type 1 binding core, domain 2	ARM repeat	1	1
Actin depolymerizing proteins	SH3-domain	1	1
Tricorn protease domain 2	ARM repeat	1	1
HAMP domain-like	EAL domain-like	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PLC-like phosphodiesterases	1	1
Ankyrin repeat	Second domain of FERM	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
BRCT domain	DNA/RNA polymerases	1	1
Cullin repeat-like	Cullin repeat-like	1	1
Ankyrin repeat	WD40 repeat-like	1	1
UBA-like	Tudor/PWWP/MBT	1	1
XRCC4, C-terminal oligomerization domain	Immunoglobulin	1	1
SAM/Pointed domain	ArfGap/RecO-like zinc finger	1	1
Mib/herc2 domain-like	UBA-like	1	1
TSP-1 type 1 repeat	PR-1-like	1	1
Caspase-like	Caspase-like	1	1
Immunoglobulin	Ribonuclease H-like	1	1
Thioesterase/thiol ester dehydrase-isomerase	Bet v1-like	1	1
Urease, beta-subunit	Metallo-dependent hydrolases	1	1
Chaperone J-domain	UBA-like	1	1
EGF/Laminin	SWIB/MDM2 domain	1	1
Spectrin repeat	WW domain	1	1
Tudor/PWWP/MBT	Fibrinogen C-terminal domain-like	1	1
WD40 repeat-like	SAM/Pointed domain	1	1
ADP-ribosylation	vWA-like	1	1
G protein-binding domain	Cysteine-rich domain	1	1
Porins	Homeodomain-like	1	1
Immunoglobulin	Thyroglobulin type-1 domain	1	1
RCC1/BLIP-II	FYVE/PHD zinc finger	1	1
L30e-like	alpha/beta knot	1	1
ISP domain	Ferritin-like	1	1
RUN domain-like	RUN domain-like	1	1
Fibrinogen C-terminal domain-like	TSP-1 type 1 repeat	1	1
E set domains	EGF/Laminin	1	1
TPR-like	TSP type-3 repeat	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
Anthrax protective antigen	Voltage-gated potassium channels	1	1
MurCD N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	1	1
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	1	1
PH domain-like	RCC1/BLIP-II	1	1
Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	1	1
ISP domain	Bet v1-like	1	1
PR-1-like	SOCS box-like	1	1
Family A G protein-coupled receptor-like	beta-lactamase/transpeptidase-like	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
Calponin-homology domain, CH-domain	Concanavalin A-like lectins/glucanases	1	1
Porins	Carboxypeptidase regulatory domain-like	1	1
PK beta-barrel domain-like	PK C-terminal domain-like	1	1
PUG domain-like	Ubiquitin-like	1	1
SMAD/FHA domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
PH domain-like	C-terminal domain of PLC-beta	1	1
Formyltransferase	ALDH-like	1	1
Terpenoid cyclases/Protein prenyltransferases	TIMP-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Ran binding protein zinc finger-like	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
beta-beta-alpha zinc fingers	Nucleotidyltransferase	1	1
Cytochrome c	4Fe-4S ferredoxins	1	1
UBA-like	Peptidyl-tRNA hydrolase II	1	1
TIMP-like	TIMP-like	1	1
Tudor/PWWP/MBT	RING/U-box	1	1
Kazal-type serine protease inhibitors	FnI-like domain	1	1
Sema domain	TSP-1 type 1 repeat	1	1
TPR-like	MgtE membrane domain-like	1	1
Protein kinase-like (PK-like)	Rhodanese/Cell cycle control phosphatase	1	1
Bacterial hemolysins	RING/U-box	1	1
P-loop containing nucleoside triphosphate hydrolases	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Thioredoxin-like	Nucleoside diphosphate kinase, NDK	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Type II DNA topoisomerase	1	1
WD40 repeat-like	Tricorn protease domain 2	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
Concanavalin A-like lectins/glucanases	FnI-like domain	1	1
NAD(P)-binding Rossmann-fold domains	ACT-like	1	1
Kelch motif	BAR/IMD domain-like	1	1
cAMP-binding domain-like	PDZ domain-like	1	1
Clavaminate synthase-like	Tudor/PWWP/MBT	1	1
GAF domain-like	PYP-like sensor domain (PAS domain)	1	1
EF-hand	FnI-like domain	1	1
Nucleotide-diphospho-sugar transferases	Nucleotidyltransferase	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
Calpain large subunit, middle domain (domain III)	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
TRAF domain-like	NRDP1 C-terminal domain-like	1	1
E set domains	Hect, E3 ligase catalytic domain	1	1
SAP domain	RNA-binding domain, RBD	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Multiheme cytochromes	Family A G protein-coupled receptor-like	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Chaperone J-domain	1	1
vWA-like	SPOC domain-like	1	1
SEA domain	RING/U-box	1	1
Cytochrome b5-like heme/steroid binding domain	UBA-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
Spermadhesin, CUB domain	Trypsin-like serine proteases	1	1
Fibronectin type III	Hect, E3 ligase catalytic domain	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
YjgF-like	YjgF-like	1	1
TNF receptor-like	TNF receptor-like	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
TPR-like	CBS-domain pair	1	1
DNA-glycosylase	Nudix	1	1
Outer arm dynein light chain 1	L domain-like	1	1
Ubiquitin-like	A middle domain of Talin 1	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
Eukaryotic type KH-domain (KH-domain type I)	HD-domain/PDEase-like	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
Cysteine proteinases	Transglutaminase, two C-terminal domains	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	1	1
Galactose-binding domain-like	BRCT domain	1	1
Fibronectin type III	Thioredoxin-like	1	1
CRAL/TRIO N-terminal domain	PapD-like	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
Ubiquitin-like	TPR-like	1	1
MIT domain	Cysteine proteinases	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
Concanavalin A-like lectins/glucanases	L domain-like	1	1
EGF/Laminin	V-type ATP synthase subunit C	1	1
F-box domain	Galactose-binding domain-like	1	1
EF-hand	Leucine zipper domain	1	1
Eukaryotic type KH-domain (KH-domain type I)	Pentein	1	1
HAD-like	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
EGF/Laminin	Lipoxigenase	1	1
Fibronectin type III	MFS general substrate transporter	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
NAD(P)-binding Rossmann-fold domains	NagB/RpiA/CoA transferase-like	1	1
PLP-dependent transferases	PreATP-grasp domain	1	1
TPR-like	Chaperone J-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	AN1-like Zinc finger	1	1
PH domain-like	NAD kinase/diacylglycerol kinase-like	1	1
PH domain-like	Phospholipase D/nuclease	1	1
Galactose-binding domain-like	Family A G protein-coupled receptor-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
Ubiquitin-like	Zn-dependent exopeptidases	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
The spindle assembly checkpoint protein mad2	FYVE/PHD zinc finger	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	CbiG N-terminal domain-like	1	1
vWA-like	Hairpin loop containing domain-like	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
PH domain-like	Glycolipid transfer protein, GLTP	1	1
F-box domain	Kelch motif	1	1
E set domains	Thioredoxin-like	1	1
PH domain-like	BSD domain-like	1	1
CHY zinc finger-like	CHY zinc finger-like	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
Bcl-2 inhibitors of programmed cell death	Invertebrate chitin-binding proteins	1	1
ArfGap/RecO-like zinc finger	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	1	1
RING/U-box	Cyclophilin-like	1	1
Cytochrome b5-like heme/steroid binding domain	Hect, E3 ligase catalytic domain	1	1
RCC1/BLIP-II	UBA-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
TAFH domain-like	HIT/MYND zinc finger-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	CalX-like	1	1
Porins	Porins	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Ankyrin repeat	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
Concanavalin A-like lectins/glucanases	FYVE/PHD zinc finger	1	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Kelch motif	Fibronectin type III	1	1
RNI-like	Voltage-gated potassium channels	1	1
C-type lectin-like	vWA-like	1	1
beta-sandwich domain of Sec23/24	Formin homology 2 domain (FH2 domain)	1	1
PRTase-like	PRTase-like	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
MIT domain	MIT domain	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
L domain-like	NTF2-like	1	1
DNase I-like	RNA-binding domain, RBD	1	1
Concanavalin A-like lectins/glucanases	Fibrinogen C-terminal domain-like	1	1
F-box domain	SMI1/KNR4-like	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
EGF/Laminin	beta-beta-alpha zinc fingers	1	1
Calcium-dependent phosphotriesterase	YWTD domain	1	1
BSD domain-like	BSD domain-like	1	1
LDL receptor-like module	Galactose-binding domain-like	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	1	1
PH domain-like	Bet v1-like	1	1
Ribonuclease H-like	Zinc finger domain of DNA polymerase-alpha	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Precorrin-8X methylmutase CbiC/CobH	1	1
Formate dehydrogenase/DMSO reductase, domains 1-3	ISP domain	1	1
Calponin-homology domain, CH-domain	SH3-domain	1	1
E set domains	Galactose-binding domain-like	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	1	1
SH2 domain	Cysteine-rich domain	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
POZ domain	Galactose-binding domain-like	1	1
RuvA domain 2-like	WD40 repeat-like	1	1
UBA-like	Thioredoxin-like	1	1
TAZ domain	Kix domain of CBP (creb binding protein)	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Serine protease inhibitors	Serine protease inhibitors	1	1
Second domain of FERM	I/LWEQ domain	1	1
3-carboxy-cis,cis-mucoante lactonizing enzyme	EGF/Laminin	1	1
FAD/NAD(P)-binding domain	EF-hand	1	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	1	1
G protein-binding domain	PH domain-like	1	1
BRK domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
PUG domain-like	Ran binding protein zinc finger-like	1	1
p53-like transcription factors	SH2 domain	1	1
Tudor/PWWP/MBT	Cytokine	1	1
E set domains	GTPase activation domain, GAP	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	beta-Roll	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
SNF-like	Bet v1-like	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-dependent enzymes	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
A heparin-binding domain	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
HAD-like	alpha/beta-Hydrolases	1	1
Homeodomain-like	EAL domain-like	1	1
WD40 repeat-like	TolB, C-terminal domain	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
SEA domain	Voltage-gated potassium channels	1	1
Ankyrin repeat	Cap-Gly domain	1	1
AF0104/ALDC/Ptd012-like	AF0104/ALDC/Ptd012-like	1	1
ISP transmembrane anchor	ISP domain	1	1
SH3-domain	beta-beta-alpha zinc fingers	1	1
Tudor/PWWP/MBT	CCHHC domain	1	1
Nucleotidylyl transferase	MOP-like	1	1
Trefoil	EGF/Laminin	1	1
TPR-like	RNA-binding domain, RBD	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
RING/U-box	ADP-ribosylglycohydrolase	1	1
Protein kinase-like (PK-like)	Toll/Interleukin receptor TIR domain	1	1
Calponin-homology domain, CH-domain	Ankyrin repeat	1	1
Growth factor receptor domain	TNF receptor-like	1	1
DBL homology domain (DH-domain)	SH2 domain	1	1
Ankyrin repeat	FabD/lysophospholipase-like	1	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	1	1
HAD-like	Protein kinase-like (PK-like)	1	1
Ankyrin repeat	PDZ domain-like	1	1
PGBD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Protein kinase-like (PK-like)	PDZ domain-like	1	1
Actin-like ATPase domain	CV3147-like	1	1
Chondroitin AC/alginate lyase	Hyaluronate lyase-like, C-terminal domain	1	1
Sensory domain-like	PR-1-like	1	1
FKBP-like	FKBP-like	1	1
PLC-like phosphodiesterases	C-type lectin-like	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	PKD domain	1	1
EF-hand	Eferin C-derminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
RAP domain-like	RAP domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	1	1
Stathmin	Stathmin	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-binding domain	1	1
TSP-1 type 1 repeat	Anthrax protective antigen	1	1
OmpA-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Acetyl-CoA synthetase-like	(Trans)glycosidases	1	1
Ras GEF	EF-hand	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
EGF/Laminin	Thioesterase/thiol ester dehydrase-isomerase	1	1
SRCR-like	Immunoglobulin	1	1
YccV-like	ApaG-like	1	1
DNase I-like	EGF/Laminin	1	1
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	1	1
SET domain	beta-lactamase/transpeptidase-like	1	1
CheW-like	CheY-like	1	1
Pentein	Translation proteins	1	1
RING/U-box	PDZ domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	FF domain	1	1
Pentapeptide repeat-like	DNase I-like	1	1
C-type lectin-like	ARM repeat	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
vWA-like	Trypsin-like serine proteases	1	1
Outer arm dynein light chain 1	P-loop containing nucleoside triphosphate hydrolases	1	1
CRAL/TRIO domain	GTPase activation domain, GAP	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
RNA-binding domain, RBD	Cysteine proteinases	1	1
GST C-terminal domain-like	Class II aaRS and biotin synthetases	1	1
SH3-domain	DEATH domain	1	1
RING/U-box	Hairpin loop containing domain-like	1	1
Nitric oxide (NO) synthase oxygenase domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Cysteine proteinases	Ribonuclease H-like	1	1
Kelch motif	SH3-domain	1	1
Phage tail proteins	gp5 N-terminal domain-like	1	1
Ubiquitin-like	SH3-domain	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
beta-beta-alpha zinc fingers	RNA-binding domain, RBD	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
TPR-like	Fic-like	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
DEATH domain	NHL repeat	1	1
Ribonuclease H-like	EGF/Laminin	1	1
Plexin repeat	E set domains	1	1
TSP-1 type 1 repeat	DEATH domain	1	1
EGF/Laminin	Kringle-like	1	1
G protein-binding domain	G protein-binding domain	1	1
Immunoglobulin	Kringle-like	1	1
Calcium-dependent phosphotriesterase	EGF/Laminin	1	1
Homeodomain-like	Nucleotide cyclase	1	1
Kringle-like	Ricin B-like lectins	1	1
NAD kinase/diacylglycerol kinase-like	CheW-like	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
WD40 repeat-like	E set domains	1	1
Dehydroquinate synthase-like	LysM domain	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
Ribosomal protein S5 domain 2-like	Ribulose-phoshate binding barrel	1	1
TPR-like	HSP20-like chaperones	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
Tudor/PWWP/MBT	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PDZ domain-like	ClpP/crotonase	1	1
Second domain of FERM	SH3-domain	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	NagB/RpiA/CoA transferase-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Concanavalin A-like lectins/glucanases	Carbohydrate-binding domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
PHM/PNGase F	NHL repeat	1	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	1	1
ENTH/VHS domain	SH3-domain	1	1
PurS-like	PurM C-terminal domain-like	1	1
dsRNA-binding domain-like	Nudix	1	1
Ubiquitin-like	Cap-Gly domain	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
Doublecortin (DC)	Protein kinase-like (PK-like)	1	1
Fibronectin type III	Anthrax protective antigen	1	1
Metallo-dependent phosphatases	EF-hand	1	1
Immunoglobulin	Hairpin loop containing domain-like	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
TPR-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
S13-like H2TH domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ubiquitin-like	XPC-binding domain	1	1
THUMP domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Porins	P-loop containing nucleoside triphosphate hydrolases	1	1
Ran binding protein zinc finger-like	RING/U-box	1	1
P-loop containing nucleoside triphosphate hydrolases	Toll/Interleukin receptor TIR domain	1	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
CheY-like	Nucleotidyltransferase	1	1
WD40 repeat-like	Putative isomerase YbhE	1	1
vWA-like	Di-copper centre-containing domain	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
Ankyrin repeat	L domain-like	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
PDZ domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	1	1
Hairpin loop containing domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
PDZ domain-like	PX domain	1	1
"Winged helix" DNA-binding domain	occludin/ELL-like	1	1
FYVE/PHD zinc finger	EF-hand	1	1
L21p-like	L21p-like	1	1
Spermadhesin, CUB domain	Complement control module/SCR domain	1	1
Histone-fold	ARM repeat	1	1
Growth factor receptor domain	Protein kinase-like (PK-like)	1	1
Cysteine proteinases	HIT/MYND zinc finger-like	1	1
MFS general substrate transporter	Ribosomal protein S5 domain 2-like	1	1
WD40 repeat-like	Cysteine proteinases	1	1
RNI-like	Galactose-binding domain-like	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Calponin-homology domain, CH-domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
Cap-Gly domain	Protein kinase-like (PK-like)	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Growth factor receptor domain	Ankyrin repeat	1	1
NagB/RpiA/CoA transferase-like	alpha-helical ferredoxin	1	1
Transmembrane di-heme cytochromes	Radical SAM enzymes	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
Rudiment single hybrid motif	Formyltransferase	1	1
R3H domain	Ankyrin repeat	1	1
Nitric oxide (NO) synthase oxygenase domain	Flavoproteins	1	1
DEK C-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Homeodomain-like	Cupredoxins	1	1
FnI-like domain	Kringle-like	1	1
Cupredoxins	HAMP domain-like	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
Anthrax protective antigen	Anthrax protective antigen	1	1
C-terminal, gelsolin-like domain of Sec23/24	Actin depolymerizing proteins	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
PurS-like	PurM N-terminal domain-like	1	1
SH3-domain	Toll/Interleukin receptor TIR domain	1	1
YWTD domain	Fibronectin type III	1	1
DNase I-like	C-type lectin-like	1	1
Macro domain-like	CRAL/TRIO domain	1	1
RNA-binding domain, RBD	NTF2-like	1	1
Growth factor receptor domain	Notch domain	1	1
Periplasmic binding protein-like II	Protein kinase-like (PK-like)	1	1
L domain-like	UBA-like	1	1
Formyltransferase	ACP-like	1	1
Hormone receptor domain	Family A G protein-coupled receptor-like	1	1
Saposin	SGNH hydrolase	1	1
PLP-dependent transferases	Adenine nucleotide alpha hydrolases-like	1	1
Thioredoxin-like	DnaJ/Hsp40 cysteine-rich domain	1	1
Family A G protein-coupled receptor-like	WD40 repeat-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
Pentapeptide repeat-like	Nucleoside diphosphate kinase, NDK	1	1
PDZ domain-like	Formin homology 2 domain (FH2 domain)	1	1
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
Acyl-CoA binding protein	ClpP/crotonase	1	1
FMN-linked oxidoreductases	Galactose-binding domain-like	1	1
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
TSP-1 type 1 repeat	Cadherin-like	1	1
RING/U-box	SH3-domain	1	1
"Winged helix" DNA-binding domain	Dimeric alpha+beta barrel	1	1
Plexin repeat	TSP-1 type 1 repeat	1	1
Glycosyl hydrolase domain	Glycosyl hydrolase domain	1	1
Ankyrin repeat	FYVE/PHD zinc finger	1	1
Concanavalin A-like lectins/glucanases	SOCS box-like	1	1
Retrovirus zinc finger-like domains	Nucleotidyltransferase	1	1
Ricin B-like lectins	Alkaline phosphatase-like	1	1
Clavaminate synthase-like	RNI-like	1	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	1	1
P-loop containing nucleoside triphosphate hydrolases	Bet v1-like	1	1
Nucleotidylyl transferase	Class II aaRS ABD-related	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
Cytochrome c oxidase subunit I-like	Cytochrome c	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
(Trans)glycosidases	(Trans)glycosidases	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Immunoglobulin	MFS general substrate transporter	1	1
Kelch motif	Growth factor receptor domain	1	1
Thioredoxin-like	FAD/NAD(P)-binding domain	1	1
SH2 domain	PLC-like phosphodiesterases	1	1
CRAL/TRIO domain	PapD-like	1	1
F-box domain	DBL homology domain (DH-domain)	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
P-loop containing nucleoside triphosphate hydrolases	MOP-like	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
vWA-like	FYVE/PHD zinc finger	1	1
PreATP-grasp domain	Formyltransferase	1	1
ACT-like	ACT-like	1	1
tRNA-guanine transglycosylase	tRNA-guanine transglycosylase	1	1
Bet v1-like	HAD-like	1	1
RING/U-box	ARM repeat	1	1
Homeodomain-like	HAMP domain-like	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	1	1
Trypsin-like serine proteases	DEATH domain	1	1
HCP-like	Cyclin-like	1	1
Protein kinase-like (PK-like)	HCP-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Retrovirus zinc finger-like domains	PAP/OAS1 substrate-binding domain	1	1
E set domains	cAMP-binding domain-like	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
CBS-domain pair	MgtE membrane domain-like	1	1
Rap/Ran-GAP	PDZ domain-like	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
Voltage-gated potassium channels	Pentapeptide repeat-like	1	1
G protein-binding domain	FYVE/PHD zinc finger	1	1
ACP-like	Trimeric LpxA-like enzymes	1	1
Amidase signature (AS) enzymes	Cytokine	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
PRP4-like	WD40 repeat-like	1	1
PLP-dependent transferases	Glutathione synthetase ATP-binding domain-like	1	1
PGBD-like	PGBD-like	1	1
RING/U-box	NRDP1 C-terminal domain-like	1	1
IP3 receptor type 1 binding core, domain 2	IP3 receptor type 1 binding core, domain 2	1	1
RCC1/BLIP-II	PABC (PABP) domain	1	1
Metalloproteases ("zincins"), catalytic domain	Complement control module/SCR domain	1	1
Calponin-homology domain, CH-domain	Thioredoxin-like	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
EAL domain-like	Metallo-dependent hydrolases	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
RCC1/BLIP-II	Tudor/PWWP/MBT	1	1
PDZ domain-like	Ras GEF	1	1
EGF/Laminin	Ankyrin repeat	1	1
ARM repeat	POZ domain	1	1
TSP-1 type 1 repeat	vWA-like	1	1
Myosin S1 fragment, N-terminal domain	Myosin rod fragments	1	1
ARM repeat	Mib/herc2 domain-like	1	1
RuvA domain 2-like	SH2 domain	1	1
Nucleotidylyl transferase	C-terminal domain of ProRS	1	1
SEA domain	Protein kinase-like (PK-like)	1	1
L domain-like	Fibronectin type III	1	1
XRCC4, N-terminal domain	Immunoglobulin	1	1
STAT	p53-like transcription factors	1	1
RING/U-box	Fibrinogen C-terminal domain-like	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Nitrite/Sulfite reductase N-terminal domain-like	CbiG N-terminal domain-like	1	1
(Phosphotyrosine protein) phosphatases II	Cysteine-rich domain	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
Apolipoprotein A-I	NHL repeat	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
SAP domain	DNase I-like	1	1
SAM/Pointed domain	Ubiquitin-like	1	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Ankyrin repeat	1	1
Nucleotide-diphospho-sugar transferases	Poly A polymerase C-terminal region-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Galactose oxidase, central domain	1	1
Ypt/Rab-GAP domain of gyp1p	Concanavalin A-like lectins/glucanases	1	1
Phage fibre proteins	(Phosphotyrosine protein) phosphatases II	1	1
RCC1/BLIP-II	RING/U-box	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Complement control module/SCR domain	TSP-1 type 1 repeat	1	1
WD40 repeat-like	RCC1/BLIP-II	1	1
N-terminal domain of MutM-like DNA repair proteins	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ubiquitin-like	HAD-like	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
HLH, helix-loop-helix DNA-binding domain	HMG-box	1	1
HD-domain/PDEase-like	HD-domain/PDEase-like	1	1
PA domain	RING/U-box	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
Agglutinin HPA-like	Kazal-type serine protease inhibitors	1	1
DNA/RNA polymerases	DNA breaking-rejoining enzymes	1	1
WW domain	NAD(P)-binding Rossmann-fold domains	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
beta-beta-alpha zinc fingers	Leucine zipper domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	1	1
PABC (PABP) domain	Hect, E3 ligase catalytic domain	1	1
RING/U-box	Trimerization domain of TRAF	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
FYVE/PHD zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	1	1
C-type lectin-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
GTPase activation domain, GAP	Bet v1-like	1	1
HR1 repeat	Protein kinase-like (PK-like)	1	1
(Trans)glycosidases	Acyl-CoA N-acyltransferases (Nat)	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
ACP-like	ALDH-like	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
SPOC domain-like	SAP domain	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
Calponin-homology domain, CH-domain	SH2 domain	1	1
TPR-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
Anthrax protective antigen	Family A G protein-coupled receptor-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	1	1
Adenine nucleotide alpha hydrolases-like	Translation proteins	1	1
ARM repeat	CalX-like	1	1
Molybdenum cofactor biosynthesis proteins	Adenine nucleotide alpha hydrolases-like	1	1
Six-hairpin glycosidases	P-loop containing nucleoside triphosphate hydrolases	1	1
C-type lectin-like	Putative cyclase	1	1
Ubiquitin-like	PUA domain-like	1	1
PYP-like sensor domain (PAS domain)	HD-domain/PDEase-like	1	1
SMAD/FHA domain	BRCT domain	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
F-box domain	YccV-like	1	1
FMT C-terminal domain-like	ALDH-like	1	1
TSP-1 type 1 repeat	PGBD-like	1	1
UBA-like	DNase I-like	1	1
Ras GEF	Cysteine-rich domain	1	1
Elafin-like	Immunoglobulin	1	1
p53-like transcription factors	p53 tetramerization domain	1	1
Tudor/PWWP/MBT	Hect, E3 ligase catalytic domain	1	1
R3H domain	RNA-binding domain, RBD	1	1
"Winged helix" DNA-binding domain	TSP-1 type 1 repeat	1	1
DUSP-like	Ubiquitin-like	1	1
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
post-AAA+ oligomerization domain-like	post-AAA+ oligomerization domain-like	1	1
(Trans)glycosidases	Restriction endonuclease-like	1	1
CAD & PB1 domains	Cysteine-rich domain	1	1
PDZ domain-like	Concanavalin A-like lectins/glucanases	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
RNI-like	Fibrinogen C-terminal domain-like	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Plexin repeat	Plexin repeat	1	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	1	1
L27 domain	L27 domain	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Precorrin-8X methylmutase CbiC/CobH	1	1
P-loop containing nucleoside triphosphate hydrolases	Nucleotidyltransferase	1	1
Second domain of FERM	A middle domain of Talin 1	1	1
alpha/beta-Hydrolases	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	1	1
DEATH domain	SH2 domain	1	1
EF-hand	C-terminal domain of PLC-beta	1	1
Ferredoxin reductase-like, C-terminal NADP-linked domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Ubiquitin-like	I/LWEQ domain	1	1
ARM repeat	PX domain	1	1
Nitric oxide (NO) synthase oxygenase domain	Riboflavin synthase domain-like	1	1
SAP domain	RING/U-box	1	1
MgtE N-terminal domain-like	MgtE membrane domain-like	1	1
MgtE membrane domain-like	MgtE membrane domain-like	1	1
Carboxypeptidase regulatory domain-like	OmpA-like	1	1
beta-beta-alpha zinc fingers	WW domain	1	1
DBL homology domain (DH-domain)	BAR/IMD domain-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Smc hinge domain	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Family A G protein-coupled receptor-like	1	1
ARM repeat	Galactose-binding domain-like	1	1
Isocitrate/Isopropylmalate dehydrogenase-like	HlyD-like secretion proteins	1	1
PR-1-like	WD40 repeat-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	MetI-like	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
Cytochrome b5-like heme/steroid binding domain	RING/U-box	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
CBS-domain pair	Nucleotide-diphospho-sugar transferases	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
RuvA domain 2-like	DNase I-like	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
FYVE/PHD zinc finger	SMAD/FHA domain	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
SAP domain	Ribonuclease H-like	1	1
L domain-like	Actin depolymerizing proteins	1	1
BRCT domain	ADP-ribosylation	1	1
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	1	1
RNI-like	Toll/Interleukin receptor TIR domain	1	1
DEATH domain	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
DUSP-like	DUSP-like	1	1
Chaperone J-domain	E set domains	1	1
TPR-like	OmpA-like	1	1
Adenine nucleotide alpha hydrolases-like	Type II DNA topoisomerase	1	1
I/LWEQ domain	I/LWEQ domain	1	1
Clavaminate synthase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
EGF/Laminin	Phosphoenolpyruvate/pyruvate domain	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
mRNA decapping enzyme DcpS N-terminal domain	HIT-like	1	1
Chaperone J-domain	EPT/RTPC-like	1	1
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
NTF2-like	UBA-like	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
Ubiquitin-like	GTPase activation domain, GAP	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Composite domain of metallo-dependent hydrolases	1	1
Restriction endonuclease-like	SWIB/MDM2 domain	1	1
Mib/herc2 domain-like	Mib/herc2 domain-like	1	1
cAMP-binding domain-like	FabD/lysophospholipase-like	1	1
Lipoxigenase	Lipoxigenase	1	1
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	1	1
F-box domain	HCP-like	1	1
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
ARM repeat	Zn-dependent exopeptidases	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
ARM repeat	Ras GEF	1	1
Ubiquitin-like	Acid proteases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
CCCH zinc finger	RNA-binding domain, RBD	1	1
Fibrinogen C-terminal domain-like	SNARE-like	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
Galactose mutarotase-like	Hyaluronate lyase-like, C-terminal domain	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	LysM domain	1	1
RCC1/BLIP-II	Galactose-binding domain-like	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	LDL receptor-like module	1	1
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	1	1
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	1	1
L domain-like	ADP-ribosylglycohydrolase	1	1
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	1	1
Flavoproteins	Radical SAM enzymes	1	1
E set domains	Terpenoid cyclases/Protein prenyltransferases	1	1
Pectin lyase-like	Tudor/PWWP/MBT	1	1
Ubiquitin-like	SMAD/FHA domain	1	1
L domain-like	PDZ domain-like	1	1
Class I glutamine amidotransferase-like	Composite domain of metallo-dependent hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	Cobalamin (vitamin B12)-dependent enzymes	1	1
Immunoglobulin	LDL receptor-like module	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
Spectrin repeat	GAS2 domain-like	1	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	1	1
PUG domain-like	Galactose-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
PKD domain	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
RING/U-box	DUSP-like	1	1
TSP-1 type 1 repeat	Periplasmic binding protein-like II	1	1
Fibronectin type III	CalX-like	1	1
"Winged helix" DNA-binding domain	PLP-dependent transferases	1	1
Sema domain	GTPase activation domain, GAP	1	1
Notch domain	Notch domain	1	1
Trypsin-like serine proteases	Trypsin-like serine proteases	1	1
Second domain of FERM	FAT domain of focal adhesion kinase	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	ACT-like	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	1	1
RNI-like	Phospholipase A2, PLA2	1	1
Tex N-terminal region-like	SH2 domain	1	1
Family A G protein-coupled receptor-like	Spectrin repeat	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
WWE domain	ADP-ribosylation	1	1
Retrovirus zinc finger-like domains	DNase I-like	1	1
Spermadhesin, CUB domain	Cadherin-like	1	1
FF domain	GTPase activation domain, GAP	1	1
WW domain	PIN domain-like	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	YWTD domain	1	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	1	1
Fibronectin type III	Ankyrin repeat	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Periplasmic binding protein-like II	1	1
ENT-like	Bromodomain	1	1
DNA breaking-rejoining enzymes	Nucleic acid-binding proteins	1	1
L domain-like	Protein kinase-like (PK-like)	1	1
Mib/herc2 domain-like	Tudor/PWWP/MBT	1	1
UBA-like	KA1-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Chaperone J-domain	Nucleotidyltransferase substrate binding subunit/domain	1	1
EGF/Laminin	Notch domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	1	1
RmlC-like cupins	RmlC-like cupins	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
Fibronectin type III	Complement control module/SCR domain	1	1
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
Ubiquitin-like	FAD-binding/transporter-associated domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Ribosomal protein S5 domain 2-like	Periplasmic binding protein-like II	1	1
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Chromo domain-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
SH2 domain	SH2 domain	1	1
Ypt/Rab-GAP domain of gyp1p	EF-hand	1	1
PDZ domain-like	BAR/IMD domain-like	1	1
Tudor/PWWP/MBT	BRCT domain	1	1
P-loop containing nucleoside triphosphate hydrolases	EGF/Laminin	1	1
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	1	1
Phosphofructokinase	Phosphofructokinase	1	1
Porins	CarD-like	1	1
RING/U-box	BRCT domain	1	1
Histone-fold	POZ domain	1	1
Spectrin repeat	RING/U-box	1	1
RNA-binding domain, RBD	SPOC domain-like	1	1
AbfB domain	Kringle-like	1	1
DEATH domain	WD40 repeat-like	1	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
GYF domain	Chaperone J-domain	1	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
Fibrinogen C-terminal domain-like	Galactose-binding domain-like	1	1
FnI-like domain	Serine protease inhibitors	1	1
EF-hand	Kelch motif	1	1
CBS-domain pair	cAMP-binding domain-like	1	1
SH3-domain	WW domain	1	1
RNA-binding domain, RBD	Nucleotidyltransferase	1	1
SH3-domain	PLC-like phosphodiesterases	1	1
Fibrinogen C-terminal domain-like	Fibronectin type III	1	1
L domain-like	RING/U-box	1	1
RING/U-box	Galactose-binding domain-like	1	1
PH domain-like	RNI-like	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
PUG domain-like	Cysteine proteinases	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
MFS general substrate transporter	PH domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
ParB/Sulfiredoxin	KorB DNA-binding domain-like	1	1
CBS-domain pair	CBS-domain pair	1	1
vWA-like	SAP domain	1	1
Tubby C-terminal domain-like	His-Me finger endonucleases	1	1
vWA-like	Sensory domain-like	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
ARM repeat	Family A G protein-coupled receptor-like	1	1
Thiolase-like	SCP-like	1	1
WD40 repeat-like	MFS general substrate transporter	1	1
Ankyrin repeat	FAD-binding/transporter-associated domain-like	1	1
UBA-like	WWE domain	1	1
SH3-domain	ARM repeat	1	1
vWA-like	SRCR-like	1	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	1	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
DBL homology domain (DH-domain)	FYVE/PHD zinc finger	1	1
Complement control module/SCR domain	C-type lectin-like	1	1
Pseudouridine synthase	PUA domain-like	1	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ATP-dependent DNA ligase DNA-binding domain	1	1
Cytochrome b5-like heme/steroid binding domain	Galactose-binding domain-like	1	1
FYVE/PHD zinc finger	SAP domain	1	1
SMAD/FHA domain	RING/U-box	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
Cytochrome P450	Cytochrome P450	1	1
ARM repeat	BEACH domain	1	1
Histone-fold	DBL homology domain (DH-domain)	1	1
GST C-terminal domain-like	S15/NS1 RNA-binding domain	1	1
ARM repeat	SAM/Pointed domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
Cupredoxins	Nucleotide cyclase	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
UBA-like	XPC-binding domain	1	1
Bromodomain	Tudor/PWWP/MBT	1	1
SH3-domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
EF-hand	NAD kinase/diacylglycerol kinase-like	1	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	1	1
Kazal-type serine protease inhibitors	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
CAD & PB1 domains	His-Me finger endonucleases	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
SAP domain	Cytochrome b5-like heme/steroid binding domain	1	1
TPR-like	Immunoglobulin	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
Outer arm dynein light chain 1	Family A G protein-coupled receptor-like	1	1
PX domain	GTPase activation domain, GAP	1	1
EGF/Laminin	TSP type-3 repeat	1	1
Ribosomal protein L25-like	C-terminal domain of ProRS	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Bromodomain	RING/U-box	1	1
S15/NS1 RNA-binding domain	C-terminal domain of ProRS	1	1
DBL homology domain (DH-domain)	Ras GEF	1	1
TSP-1 type 1 repeat	C-type lectin-like	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	1	1
Ubiquitin-like	ADP-ribosylation	1	1
Ribonuclease H-like	SH2 domain	1	1
WD40 repeat-like	SNARE fusion complex	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	ARM repeat	1	1
Sema domain	E set domains	1	1
Fibronectin type III	Family A G protein-coupled receptor-like	1	1
F-box domain	Fibrinogen C-terminal domain-like	1	1
Tudor/PWWP/MBT	Galactose-binding domain-like	1	1
HlyD-like secretion proteins	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
Thioredoxin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	1	1
Alpha-L RNA-binding motif	Pseudouridine synthase	1	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	1	1
FMN-linked oxidoreductases	dsRNA-binding domain-like	1	1
PH domain-like	A middle domain of Talin 1	1	1
Concanavalin A-like lectins/glucanases	Serine protease inhibitors	1	1
SRCR-like	Trypsin-like serine proteases	1	1
beta-beta-alpha zinc fingers	PAP/OAS1 substrate-binding domain	1	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
AbfB domain	AbfB domain	1	1
EGF/Laminin	Invertebrate chitin-binding proteins	1	1
DBL homology domain (DH-domain)	SGNH hydrolase	1	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	1	1
Class II aaRS ABD-related	C-terminal domain of ProRS	1	1
Trefoil	Concanavalin A-like lectins/glucanases	1	1
Concanavalin A-like lectins/glucanases	PH domain-like	1	1
Alkaline phosphatase-like	His-Me finger endonucleases	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Ribonuclease H-like	CCCH zinc finger	1	1
Surp module (SWAP domain)	Surp module (SWAP domain)	1	1
Urease, gamma-subunit	Urease, beta-subunit	1	1
RNI-like	Fibronectin type III	1	1
SH3-domain	RUN domain-like	1	1
Lipoxigenase	beta-beta-alpha zinc fingers	1	1
WW domain	FF domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
HAD-like	Acyl-CoA dehydrogenase NM domain-like	1	1
MetI-like	MetI-like	1	1
A middle domain of Talin 1	I/LWEQ domain	1	1
RING/U-box	WWE domain	1	1
Ribulose-phoshate binding barrel	Periplasmic binding protein-like II	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	1	1
E2F-DP heterodimerization region	Alkaline phosphatase-like	1	1
BEACH domain	FYVE/PHD zinc finger	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
Galactose-binding domain-like	Bet v1-like	1	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	1	1
Domain of poly(ADP-ribose) polymerase	vWA-like	1	1
PH domain-like	I/LWEQ domain	1	1
Precorrin-8X methylmutase CbiC/CobH	CbiG N-terminal domain-like	1	1
Galactose-binding domain-like	Hyaluronate lyase-like, C-terminal domain	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Glycerol-3-phosphate (1)-acyltransferase	Glycerol-3-phosphate (1)-acyltransferase	1	1
ISP domain	FAD/NAD(P)-binding domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Protein kinase-like (PK-like)	L27 domain	1	1
EGF/Laminin	SEA domain	1	1
CAD & PB1 domains	PDZ domain-like	1	1
NAP-like	Ankyrin repeat	1	1
Tricorn protease domain 2	TPR-like	1	1
ARM repeat	EF-hand	1	1
Calponin-homology domain, CH-domain	DNA/RNA polymerases	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Pre-PUA domain	PUA domain-like	1	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	1	1
vWA-like	Cysteine proteinases	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
Kringle-like	Concanavalin A-like lectins/glucanases	1	1
Retrovirus zinc finger-like domains	Acid proteases	1	1
EF-hand	GAF domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
Ankyrin repeat	Hect, E3 ligase catalytic domain	1	1
RING/U-box	RNA-binding domain, RBD	1	1
Ricin B-like lectins	Immunoglobulin	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
Immunoglobulin	Fibrinogen C-terminal domain-like	1	1
Immunoglobulin	Hormone receptor domain	1	1
L domain-like	EGF/Laminin	1	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	SH2 domain	1	1
V-type ATP synthase subunit C	Phosphoenolpyruvate/pyruvate domain	1	1
GST C-terminal domain-like	C-terminal domain of ProRS	1	1
dsRNA-binding domain-like	R3H domain	1	1
SMAD/FHA domain	dsRNA-binding domain-like	1	1
CAD & PB1 domains	Six-hairpin glycosidases	1	1
SEA domain	Family A G protein-coupled receptor-like	1	1
lambda repressor-like DNA-binding domains	TNF-like	1	1
RNA-binding domain, RBD	PABC (PABP) domain	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
ARM repeat	Second domain of FERM	1	1
beta-N-acetylhexosaminidase-like domain	EGF/Laminin	1	1
CCHHC domain	CCHHC domain	1	1
Apolipoprotein A-I	E set domains	1	1
P-loop containing nucleoside triphosphate hydrolases	Fibrinogen C-terminal domain-like	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	1	1
F-box domain	RING/U-box	1	1
Rhomboid-like	UBA-like	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Hairpin loop containing domain-like	Six-hairpin glycosidases	1	1
Hairpin loop containing domain-like	DNA/RNA polymerases	1	1
Ribonuclease H-like	HRDC-like	1	1
PUA domain-like	eIF1-like	1	1
USP8 N-terminal domain-like	WW domain	1	1
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	1	1
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	1	1
L domain-like	Hormone receptor domain	1	1
vWA-like	Immunoglobulin	1	1
P-loop containing nucleoside triphosphate hydrolases	Alkaline phosphatase-like	1	1
Microbial and mitochondrial ADK, insert "zinc finger" domain	Microbial and mitochondrial ADK, insert "zinc finger" domain	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
SRCR-like	EGF/Laminin	1	1
Glycerol-3-phosphate (1)-acyltransferase	Cysteine proteinases	1	1
Nucleotidylyl transferase	Nucleotidylyl transferase	1	1
F-box domain	PH domain-like	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Second domain of FERM	DBL homology domain (DH-domain)	1	1
C-type lectin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
UBA-like	RNI-like	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
vWA-like	PR-1-like	1	1
WW domain	dsRNA-binding domain-like	1	1
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ricin B-like lectins	Spermadhesin, CUB domain	1	1
TNF-like	TNF-like	1	1
Thioredoxin-like	Family A G protein-coupled receptor-like	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
LDL receptor-like module	Lipovitellin-phosvitin complex; beta-sheet shell regions	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
BAR/IMD domain-like	Ankyrin repeat	1	1
Phospholipase A2, PLA2	Phospholipase A2, PLA2	1	1
Isocitrate/Isopropylmalate dehydrogenase-like	Porins	1	1
Clavaminate synthase-like	Tetraspanin	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
Family A G protein-coupled receptor-like	ABC transporter transmembrane region	1	1
TAFH domain-like	Histone-fold	1	1
Thioredoxin-like	AraD/HMP-PK domain-like	1	1
BRCT domain	WGR domain-like	1	1
Adenine nucleotide alpha hydrolases-like	P-loop containing nucleoside triphosphate hydrolases	1	1
PHM/PNGase F	BPTI-like	1	1
Galactose-binding domain-like	Voltage-gated potassium channels	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
SEA domain	TPR-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
Immunoglobulin	Invertebrate chitin-binding proteins	1	1
RNase III domain-like	RNase III domain-like	1	1
Ferritin-like	Ferritin-like	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
Cytochrome b5-like heme/steroid binding domain	Mib/herc2 domain-like	1	1
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	1	1
Notch domain	Ankyrin repeat	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Putative DNA-binding domain	SAND domain-like	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
RuvA domain 2-like	F-box domain	1	1
Adhesin YadA, collagen-binding domain	Tropomyosin	1	1
DNase I-like	GTPase activation domain, GAP	1	1
Trefoil	LDL receptor-like module	1	1
RCC1/BLIP-II	Mib/herc2 domain-like	1	1
BPTI-like	Serine protease inhibitors	1	1
TAZ domain	TAZ domain	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
FabD/lysophospholipase-like	EF-hand	1	1
Homeodomain-like	TNF-like	1	1
TROVE domain-like	vWA-like	1	1
L domain-like	SAM/Pointed domain	1	1
Doublecortin (DC)	Ricin B-like lectins	1	1
PUA domain-like	Ribosomal protein S5 domain 2-like	1	1
UBA-like	Galactose-binding domain-like	1	1
USP8 N-terminal domain-like	Rhodanese/Cell cycle control phosphatase	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
Band 7/SPFH domain	SCP-like	1	1
V-type ATP synthase subunit C	Thioesterase/thiol ester dehydrase-isomerase	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
MIR domain	ARM repeat	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Intermediate filament protein, coiled coil region	Intermediate filament protein, coiled coil region	1	1
TATA-box binding protein-like	TATA-box binding protein-like	1	1
Hairpin loop containing domain-like	Kringle-like	1	1
Concanavalin A-like lectins/glucanases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	1	1
CheY-like	Methylesterase CheB, C-terminal domain	1	1
PH domain-like	FAT domain of focal adhesion kinase	1	1
tRNA-binding arm	Class II aaRS and biotin synthetases	1	1
Periplasmic binding protein-like II	Nucleotide cyclase	1	1
EF-hand	DUSP-like	1	1
Bromodomain	HMG-box	1	1
ARID-like	FYVE/PHD zinc finger	1	1
Ribonuclease H-like	Fibronectin type III	1	1
L domain-like	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
RING/U-box	Protein kinase-like (PK-like)	1	1
L domain-like	WD40 repeat-like	1	1
Homeodomain-like	JAB1/MPN domain	1	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
F-box domain	Voltage-gated potassium channels	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
FYVE/PHD zinc finger	SET domain	1	1
Fibronectin type III	SAM/Pointed domain	1	1
TRAF domain-like	TPR-like	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
WW domain	FKBP-like	1	1
Actin-like ATPase domain	CheW-like	1	1
Fibrinogen C-terminal domain-like	Voltage-gated potassium channels	1	1
XRCC4, N-terminal domain	DNase I-like	1	1
Cysteine proteinases	Ankyrin repeat	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Nucleic acid-binding proteins	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
TAZ domain	Bromodomain	1	1
WD40 repeat-like	Hect, E3 ligase catalytic domain	1	1
SAP domain	Family A G protein-coupled receptor-like	1	1
Ubiquitin-like	FYVE/PHD zinc finger	1	1
Rhodanese/Cell cycle control phosphatase	WW domain	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
F-box domain	Cyclin-like	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
Galactose-binding domain-like	SAM/Pointed domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
Histone-fold	Macro domain-like	1	1
F-box domain	ApaG-like	1	1
RCC1/BLIP-II	Cytochrome b5-like heme/steroid binding domain	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Protein kinase-like (PK-like)	1	1
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Chaperone J-domain	1	1
PTPA-like	PTPA-like	1	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	1	1
Cytochrome b5-like heme/steroid binding domain	Tudor/PWWP/MBT	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
EAL domain-like	Composite domain of metallo-dependent hydrolases	1	1
alpha/beta-Hydrolases	Carbamate kinase-like	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Fibronectin type III	1	1
PDZ domain-like	Regulator of G-protein signaling, RGS	1	1
LDL receptor-like module	Fibronectin type III	1	1
Tudor/PWWP/MBT	EGF/Laminin	1	1
Metallo-hydrolase/oxidoreductase	Macro domain-like	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Chaperone J-domain	ARM repeat	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
Rap/Ran-GAP	Rap/Ran-GAP	1	1
HIT-like	HIT-like	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
Ankyrin repeat	HIT/MYND zinc finger-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
EF-hand	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	1	1
Ankyrin repeat	SOCS box-like	1	1
Regulator of G-protein signaling, RGS	Ubiquitin-like	1	1
Actin-like ATPase domain	NAD kinase/diacylglycerol kinase-like	1	1
Tricorn protease domain 2	DPP6 N-terminal domain-like	1	1
Concanavalin A-like lectins/glucanases	BEACH domain	1	1
RNI-like	Concanavalin A-like lectins/glucanases	1	1
Plexin repeat	GTPase activation domain, GAP	1	1
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	1	1
P-loop containing nucleoside triphosphate hydrolases	WW domain	1	1
POZ domain	WD40 repeat-like	1	1
EF-hand	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	1	1
Hypothetical protein c14orf129, hspc210	ARM repeat	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
Cysteine proteinases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Restriction endonuclease-like	DEK C-terminal domain	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Cysteine proteinases	Globin-like	1	1
SRCR-like	LDL receptor-like module	1	1
Quinoprotein alcohol dehydrogenase-like	EF-hand	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
EF-hand	GAS2 domain-like	1	1
Tudor/PWWP/MBT	SET domain	1	1
E set domains	AMPKBI-like	1	1
NTF2-like	Fibrinogen C-terminal domain-like	1	1
SMAD/FHA domain	PH domain-like	1	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	1	1
B-box zinc-binding domain	TRAF domain-like	1	1
MFS general substrate transporter	Ribulose-phoshate binding barrel	1	1
HSP20-like chaperones	Riboflavin synthase domain-like	1	1
DNA/RNA polymerases	DHH phosphoesterases	1	1
Actin-like ATPase domain	AF1104-like	1	1
GST C-terminal domain-like	Class II aaRS ABD-related	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
Tropomyosin	Class II aaRS ABD-related	1	1
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	1	1
Tubby C-terminal domain-like	DNA/RNA polymerases	1	1
Ypt/Rab-GAP domain of gyp1p	EGF/Laminin	1	1
Starch-binding domain-like	(Phosphotyrosine protein) phosphatases II	1	1
FF domain	FF domain	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
S-adenosyl-L-methionine-dependent methyltransferases	YebC-like	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
BRCT domain	DBL homology domain (DH-domain)	1	1
ARM repeat	FYVE/PHD zinc finger	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
Lamin A/C globular tail domain	WD40 repeat-like	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
EGF/Laminin	DEK C-terminal domain	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
SH2 domain	Ankyrin repeat	1	1
TSP-1 type 1 repeat	SEA domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
RNA-binding domain, RBD	TSP-1 type 1 repeat	1	1
FMT C-terminal domain-like	ACP-like	1	1
Actin-like ATPase domain	CheY-like	1	1
ACT-like	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
RING/U-box	Tricorn protease domain 2	1	1
I/LWEQ domain	alpha-catenin/vinculin-like	1	1
Phase 1 flagellin	Phase 1 flagellin	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
Kix domain of CBP (creb binding protein)	RING/U-box	1	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	1	1
Nucleotide-diphospho-sugar transferases	Ribosomal protein S5 domain 2-like	1	1
TPR-like	PIN domain-like	1	1
Clc chloride channel	Clc chloride channel	1	1
POZ domain	Skp1 dimerisation domain-like	1	1
Homeodomain-like	SIS domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	1	1
CSL zinc finger	CSL zinc finger	1	1
SH2 domain	Ras GEF	1	1
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	1	1
EGF/Laminin	Tropomyosin	1	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	1	1
WW domain	RING/U-box	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
L domain-like	DNase I-like	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
Protease propeptides/inhibitors	Protease propeptides/inhibitors	1	1
Ubiquitin-like	BAG domain	1	1
EGF/Laminin	TIMP-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	1	1
Sialidases	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
PDZ domain-like	Cysteine-rich domain	1	1
EPT/RTPC-like	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	1	1
SWIB/MDM2 domain	eIF1-like	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
PUG domain-like	RING/U-box	1	1
ARM repeat	Tudor/PWWP/MBT	1	1
Ubiquitin-like	FAT domain of focal adhesion kinase	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
Concanavalin A-like lectins/glucanases	DNase I-like	1	1
HR1 repeat	HR1 repeat	1	1
Thioredoxin-like	FabD/lysophospholipase-like	1	1
Second domain of FERM	Ras GEF	1	1
TAZ domain	RING/U-box	1	1
Subtilisin-like	Subtilisin-like	1	1
HAMP domain-like	Homodimeric domain of signal transducing histidine kinase	1	1
Ribonuclease H-like	RNA-binding domain, RBD	1	1
E set domains	Transglutaminase, two C-terminal domains	1	1
Multidrug efflux transporter AcrB transmembrane domain	DNA breaking-rejoining enzymes	1	1
Concanavalin A-like lectins/glucanases	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	VPS9 domain	1	1
EGF/Laminin	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Outer arm dynein light chain 1	WD40 repeat-like	1	1
Cupredoxins	EAL domain-like	1	1
PYP-like sensor domain (PAS domain)	Nucleotide cyclase	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
PLP-dependent transferases	PLP-dependent transferases	1	1
beta-N-acetylhexosaminidase-like domain	Galactose-binding domain-like	1	1
Kix domain of CBP (creb binding protein)	Bromodomain	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Glutathione synthetase ATP-binding domain-like	Formyltransferase	1	1
SMI1/KNR4-like	ApaG-like	1	1
Growth factor receptor domain	TSP type-3 repeat	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
PH domain-like	Cullin repeat-like	1	1
Ribosomal protein L25-like	Class II aaRS ABD-related	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
HR1 repeat	PDZ domain-like	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Cyclophilin-like	TPR-like	1	1
UBC-like	Ribosomal protein S5 domain 2-like	1	1
Tropomyosin	RNI-like	1	1
RING/U-box	Hect, E3 ligase catalytic domain	1	1
Kazal-type serine protease inhibitors	Concanavalin A-like lectins/glucanases	1	1
WD40 repeat-like	DPP6 N-terminal domain-like	1	1
HAMP domain-like	Nucleotide cyclase	1	1
FYVE/PHD zinc finger	RNI-like	1	1
XRCC4, C-terminal oligomerization domain	DNase I-like	1	1
Nucleotide-diphospho-sugar transferases	GHMP Kinase, C-terminal domain	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
Concanavalin A-like lectins/glucanases	Ricin B-like lectins	1	1
BRCT domain	PH domain-like	1	1
GYF domain	ARM repeat	1	1
Spermadhesin, CUB domain	SEA domain	1	1
PH domain-like	Ran binding protein zinc finger-like	1	1
Ypt/Rab-GAP domain of gyp1p	SH3-domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	1	1
Growth factor receptor domain	Immunoglobulin	1	1
Ribulose-phoshate binding barrel	all-alpha NTP pyrophosphatases	1	1
Pentapeptide repeat-like	Concanavalin A-like lectins/glucanases	1	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	1	1
SIS domain	SIS domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	1	1
WD40 repeat-like	Bromodomain	1	1
MFS general substrate transporter	Periplasmic binding protein-like II	1	1
NAD kinase/diacylglycerol kinase-like	CheY-like	1	1
Galactose-binding domain-like	Kelch motif	1	1
Cupredoxins	Pectin lyase-like	1	1
ARM repeat	beta-sandwich domain of Sec23/24	1	1
TPR-like	MgtE N-terminal domain-like	1	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	1	1
R3H domain	AN1-like Zinc finger	1	1
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	1	1
Ankyrin repeat	EF-hand	1	1
RNA-binding domain, RBD	F-box domain	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
(Trans)glycosidases	Invertebrate chitin-binding proteins	1	1
Adhesin YadA, collagen-binding domain	Pseudouridine synthase	1	1
P-loop containing nucleoside triphosphate hydrolases	Phospholipase A2, PLA2	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
NAD(P)-binding Rossmann-fold domains	RING/U-box	1	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
EF-hand	Dimeric alpha+beta barrel	1	1
EF-hand	Tropomyosin	1	1
UBA-like	Ricin B-like lectins	1	1
P-loop containing nucleoside triphosphate hydrolases	PEBP-like	1	1
PGBD-like	L,D-transpeptidase catalytic domain-like	1	1
Ribosomal protein L25-like	S15/NS1 RNA-binding domain	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
MgtE N-terminal domain-like	CBS-domain pair	1	1
A heparin-binding domain	Amyloid beta a4 protein copper binding domain (domain 2)	1	1
Amyloid beta a4 protein copper binding domain (domain 2)	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
EF-hand	PX domain	1	1
TPR-like	Ankyrin repeat	1	1
ARM repeat	WWE domain	1	1
EAL domain-like	HD-domain/PDEase-like	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
SMAD/FHA domain	PDZ domain-like	1	1
RING/U-box	R3H domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
ARM repeat	Fibronectin type III	1	1
GAF domain-like	Phosphoglucomutase, first 3 domains	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Fibronectin type III	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Voltage-gated potassium channels	1	1
DNA/RNA polymerases	MFS general substrate transporter	1	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	1	1
TPR-like	UBA-like	1	1
Kazal-type serine protease inhibitors	Thyroglobulin type-1 domain	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
CalX-like	(Phosphotyrosine protein) phosphatases II	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
E set domains	Cupredoxins	1	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
BPTI-like	Elafin-like	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
F-box domain	Fibronectin type III	1	1
Ricin B-like lectins	Galactose-binding domain-like	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	1	1
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Hairpin loop containing domain-like	SNARE-like	1	1
Second domain of FERM	Protein kinase-like (PK-like)	1	1
Ubiquitin-like	Zn-binding ribosomal proteins	1	1
TolB, C-terminal domain	TPR-like	1	1
"Winged helix" DNA-binding domain	Ras GEF	1	1
Ubiquitin-like	alpha-catenin/vinculin-like	1	1
SRCR-like	Spermadhesin, CUB domain	1	1
Concanavalin A-like lectins/glucanases	ADP-ribosylation	1	1
Histone-fold	Ankyrin repeat	1	1
Nucleotide cyclase	Composite domain of metallo-dependent hydrolases	1	1
PH domain-like	Ypt/Rab-GAP domain of gyp1p	1	1
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	1	1
Family A G protein-coupled receptor-like	POZ domain	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	1	1
vWA-like	Growth factor receptor domain	1	1
DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	1	1
Indigoidine synthase A-like	Ribokinase-like	1	1
Restriction endonuclease-like	EGF/Laminin	1	1