Domain combination pairs in Nematostella vectensis 1.0

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

2334 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
EGF/Laminin	EGF/Laminin	220	100
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	190	48
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	136	53
Immunoglobulin	Immunoglobulin	120	61
Galactose-binding domain-like	Galactose-binding domain-like	98	22
Nicotinic receptor ligand binding domain-like	Neurotransmitter-gated ion-channel transmembrane pore	91	3
Growth factor receptor domain	EGF/Laminin	89	66
TSP-1 type 1 repeat	TSP-1 type 1 repeat	86	25
TPR-like	TPR-like	83	28
Growth factor receptor domain	Growth factor receptor domain	64	47
RING/U-box	B-box zinc-binding domain	61	15
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	49	9
Cadherin-like	Cadherin-like	49	30
Voltage-gated potassium channels	Voltage-gated potassium channels	44	11
RNA-binding domain, RBD	RNA-binding domain, RBD	43	20
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	43	17
POZ domain	Voltage-gated potassium channels	43	5
Actin-like ATPase domain	Actin-like ATPase domain	41	11
ARM repeat	ARM repeat	40	24
POZ domain	Kelch motif	40	8
Spermadhesin, CUB domain	Spermadhesin, CUB domain	39	20
Concanavalin A-like lectins/glucanases	Concanavalin A-like lectins/glucanases	34	25
Immunoglobulin	Fibronectin type III	32	26
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	32	16
EF-hand	EF-hand	31	17
Fibronectin type III	Fibronectin type III	31	27
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	30	3
LDL receptor-like module	LDL receptor-like module	30	15
ABC transporter transmembrane region	ABC transporter transmembrane region	29	6
DBL homology domain (DH-domain)	PH domain-like	28	19
RING/U-box	TRAF domain-like	28	14
Concanavalin A-like lectins/glucanases	EGF/Laminin	27	24
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	27	11
SRCR-like	SRCR-like	27	9
Hairpin loop containing domain-like	Fibrinogen C-terminal domain-like	27	10
CalX-like	CalX-like	26	16
F-box domain	RNI-like	26	9
WD40 repeat-like	WD40 repeat-like	26	15
Thioredoxin-like	GST C-terminal domain-like	25	2
Homeodomain-like	Homeodomain-like	25	16
B-box zinc-binding domain	E set domains	25	12
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	23	10
Complement control module/SCR domain	Complement control module/SCR domain	22	16
PH domain-like	Ubiquitin-like	21	13
RING/U-box	RING/U-box	21	14
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	21	2
Kazal-type serine protease inhibitors	Kazal-type serine protease inhibitors	21	10
PH domain-like	Second domain of FERM	21	13
RNI-like	RNI-like	21	8
Ubiquitin-like	Second domain of FERM	21	12
EGF/Laminin	Galactose-binding domain-like	20	14
Glutathione synthetase ATP-binding domain-like	PreATP-grasp domain	20	14
HAD-like	Calcium ATPase, transmembrane domain M	20	6
Thioredoxin-like	Thioredoxin-like	19	11
PH domain-like	PH domain-like	19	16
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	19	4
Calcium ATPase, transduction domain A	HAD-like	19	5
Voltage-gated potassium channels	cAMP-binding domain-like	19	9
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	19	5
vWA-like	vWA-like	19	13
Periplasmic binding protein-like II	Voltage-gated potassium channels	18	7
ARM repeat	Protein kinase-like (PK-like)	18	13
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	18	6
RING/U-box	E set domains	18	8
Metalloproteases ("zincins"), catalytic domain	TSP-1 type 1 repeat	18	15
Glucocorticoid receptor-like (DNA-binding domain)	Nuclear receptor ligand-binding domain	18	3
TRAF domain-like	TRAF domain-like	17	9
GroEL equatorial domain-like	GroEL apical domain-like	17	4
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	17	3
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	17	2
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	17	3
L domain-like	Family A G protein-coupled receptor-like	17	6
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	17	3
EGF/Laminin	Fibrinogen C-terminal domain-like	17	8
MFS general substrate transporter	MFS general substrate transporter	17	5
E set domains	NHL repeat	17	8
Actin depolymerizing proteins	Actin depolymerizing proteins	16	12
SH3-domain	SH3-domain	16	12
Cyclin-like	Cyclin-like	16	4
PDZ domain-like	PDZ domain-like	16	14
FYVE/PHD zinc finger	FYVE/PHD zinc finger	16	12
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	16	9
PA domain	Zn-dependent exopeptidases	16	2
Hairpin loop containing domain-like	EGF/Laminin	16	11
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	16	6
Thyroglobulin type-1 domain	Thyroglobulin type-1 domain	16	3
Spectrin repeat	Spectrin repeat	16	16
PGBD-like	Metalloproteases ("zincins"), catalytic domain	15	5
EGF/Laminin	Cadherin-like	15	11
B-box zinc-binding domain	NHL repeat	15	6
PA domain	Transferrin receptor-like dimerisation domain	15	1
Kelch motif	Kelch motif	15	8
Composite domain of metallo-dependent hydrolases	Metallo-dependent hydrolases	15	10
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	14	6
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	14	5
RING/U-box	NHL repeat	14	5
BAR/IMD domain-like	SH3-domain	14	8
Thiolase-like	Thiolase-like	14	2
cAMP-binding domain-like	cAMP-binding domain-like	14	8
GroEL equatorial domain-like	GroEL-intermediate domain like	14	3
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	13	4
Family A G protein-coupled receptor-like	Family A G protein-coupled receptor-like	13	6
EGF/Laminin	YWTD domain	13	11
Tudor/PWWP/MBT	Tudor/PWWP/MBT	13	12
GroEL-intermediate domain like	GroEL apical domain-like	13	2
(Trans)glycosidases	Glycosyl hydrolase domain	13	6
GroES-like	NAD(P)-binding Rossmann-fold domains	13	1
Pentapeptide repeat-like	Pentapeptide repeat-like	12	7
Hairpin loop containing domain-like	Concanavalin A-like lectins/glucanases	12	5
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	12	10
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	12	12
Guanido kinase N-terminal domain	Glutamine synthetase/guanido kinase	12	4
SH3-domain	PH domain-like	12	12
Ubiquitin-like	Ubiquitin-like	12	11
Protein kinase-like (PK-like)	Nucleotide cyclase	11	3
C-type lectin-like	C-type lectin-like	11	8
Nucleic acid-binding proteins	Nucleic acid-binding proteins	11	10
F-box domain	WD40 repeat-like	11	6
Quinoprotein alcohol dehydrogenase-like	WD40 repeat-like	11	10
Galactose-binding domain-like	(Trans)glycosidases	11	5
E set domains	E set domains	11	10
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	11	3
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	11	5
P-loop containing nucleoside triphosphate hydrolases	DEATH domain	10	10
Histone-fold	Histone-fold	10	2
PreATP-grasp domain	Rudiment single hybrid motif	10	7
P-loop containing nucleoside triphosphate hydrolases	Nucleic acid-binding proteins	10	5
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	10	3
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	10	5
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	10	4
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	10	7
Fibronectin type III	Voltage-gated potassium channels	10	10
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	10	4
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	10	2
CoA-dependent acyltransferases	CoA-dependent acyltransferases	10	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	9	4
Periplasmic binding protein-like I	Periplasmic binding protein-like II	9	7
lambda repressor-like DNA-binding domains	Homeodomain-like	9	2
L domain-like	L domain-like	9	8
SH3-domain	P-loop containing nucleoside triphosphate hydrolases	9	9
Subtilisin-like	Galactose-binding domain-like	9	4
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	9	7
P-loop containing nucleoside triphosphate hydrolases	TPR-like	9	7
POZ domain	POZ domain	9	7
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	9	6
PH domain-like	GTPase activation domain, GAP	9	8
WW domain	WW domain	9	8
Protease propeptides/inhibitors	Subtilisin-like	9	4
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	9	4
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	9	5
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	9	7
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	8	8
TPR-like	HCP-like	8	8
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	8	3
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	8	3
LDL receptor-like module	YWTD domain	8	8
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	8	8
SET domain	beta-beta-alpha zinc fingers	8	5
P-loop containing nucleoside triphosphate hydrolases	SMAD/FHA domain	8	6
Protein kinase-like (PK-like)	C2 domain (Calcium/lipid-binding domain, CaLB)	8	7
Spermadhesin, CUB domain	EGF/Laminin	8	8
Hairpin loop containing domain-like	Galactose-binding domain-like	8	5
EF-hand	PLC-like phosphodiesterases	8	8
RNI-like	EF-hand	8	4
FYVE/PHD zinc finger	Bromodomain	8	6
Nucleotide-diphospho-sugar transferases	Ricin B-like lectins	8	2
Calponin-homology domain, CH-domain	Spectrin repeat	8	8
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	8	5
UBA-like	Ubiquitin-like	8	8
MFS general substrate transporter	Kazal-type serine protease inhibitors	8	2
Ribonuclease H-like	DNA/RNA polymerases	8	7
PHM/PNGase F	PHM/PNGase F	8	3
Concanavalin A-like lectins/glucanases	Metalloproteases ("zincins"), catalytic domain	8	2
Concanavalin A-like lectins/glucanases	Fibronectin type III	8	7
Concanavalin A-like lectins/glucanases	C-type lectin-like	8	7
HLH, helix-loop-helix DNA-binding domain	PYP-like sensor domain (PAS domain)	8	6
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	8	2
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	7	6
Cysteine-rich domain	Cysteine-rich domain	7	6
TSP-1 type 1 repeat	Fibronectin type III	7	7
Cullin homology domain	"Winged helix" DNA-binding domain	7	3
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	7	4
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	7	5
BRCT domain	BRCT domain	7	7
Kazal-type serine protease inhibitors	EF-hand	7	5
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	7	2
Insect cysteine-rich antifreeze protein	Insect cysteine-rich antifreeze protein	7	4
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	7	3
Complement control module/SCR domain	EGF/Laminin	7	7
PDZ domain-like	SH3-domain	7	7
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	7	4
vWA-like	EGF/Laminin	7	5
PH domain-like	(Phosphotyrosine protein) phosphatases II	7	5
LDL receptor-like module	EGF/Laminin	7	7
Cadherin-like	Concanavalin A-like lectins/glucanases	7	7
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	7	3
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	7	4
Kelch motif	Galactose oxidase, central domain	7	4
Protease propeptides/inhibitors	Galactose-binding domain-like	7	2
Periplasmic binding protein-like I	Growth factor receptor domain	7	3
Invertebrate chitin-binding proteins	Invertebrate chitin-binding proteins	7	7
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	7	5
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	7	4
RING/U-box	WD40 repeat-like	7	5
DEATH domain	DEATH domain	7	7
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	7	4
Rudiment single hybrid motif	Single hybrid motif	6	3
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	6	4
L domain-like	Growth factor receptor domain	6	5
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	6	2
PDZ domain-like	PH domain-like	6	6
PAZ domain	Ribonuclease H-like	6	4
PDZ domain-like	P-loop containing nucleoside triphosphate hydrolases	6	6
POZ domain	Galactose oxidase, central domain	6	3
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	6	4
Cullin repeat-like	Cullin homology domain	6	2
Growth factor receptor domain	YWTD domain	6	6
Cullin repeat-like	"Winged helix" DNA-binding domain	6	2
P-loop containing nucleoside triphosphate hydrolases	RNI-like	6	5
FYVE/PHD zinc finger	PH domain-like	6	6
PreATP-grasp domain	Single hybrid motif	6	3
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	6	5
Galactose-binding domain-like	Fibronectin type III	6	6
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	6	1
WD40 repeat-like	ARM repeat	6	6
Concanavalin A-like lectins/glucanases	Growth factor receptor domain	6	6
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	6	5
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	6	5
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	6	2
dsRNA-binding domain-like	dsRNA-binding domain-like	6	6
Ligand-binding domain in the NO signalling and Golgi transport	Nucleotide cyclase	6	2
FAS1 domain	FAS1 domain	6	5
PDZ domain-like	Ubiquitin-like	6	6
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	6	3
Periplasmic binding protein-like I	Protein kinase-like (PK-like)	6	5
PH domain-like	ArfGap/RecO-like zinc finger	6	6
BEACH domain	WD40 repeat-like	6	5
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	6	3
Glucocorticoid receptor-like (DNA-binding domain)	Homeodomain-like	6	4
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	6	1
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	6	3
SH2 domain	PH domain-like	6	4
HLH, helix-loop-helix DNA-binding domain	Orange domain-like	6	3
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	6	3
SH3-domain	DBL homology domain (DH-domain)	6	6
GAF domain-like	GAF domain-like	6	4
Nucleotide cyclase	EAL domain-like	6	3
L27 domain	PDZ domain-like	6	6
RING/U-box	Cysteine proteinases	6	5
EF-G C-terminal domain-like	EF-G C-terminal domain-like	6	5
PKD domain	PKD domain	6	6
Cysteine-rich domain	Protein kinase-like (PK-like)	6	5
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	6	6
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	5	5
Galactose-binding domain-like	Concanavalin A-like lectins/glucanases	5	5
Fibrinogen C-terminal domain-like	Fibrinogen C-terminal domain-like	5	3
Metalloproteases ("zincins"), catalytic domain	Metalloproteases ("zincins"), catalytic domain	5	4
"Winged helix" DNA-binding domain	Periplasmic binding protein-like II	5	1
Folate-binding domain	Aminomethyltransferase beta-barrel domain	5	3
C2 domain (Calcium/lipid-binding domain, CaLB)	GTPase activation domain, GAP	5	5
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	5	5
Metalloproteases ("zincins"), catalytic domain	Blood coagulation inhibitor (disintegrin)	5	2
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	5	1
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	5	5
t-snare proteins	SNARE fusion complex	5	3
Plexin repeat	EGF/Laminin	5	3
SAM/Pointed domain	SAM/Pointed domain	5	4
WD40 repeat-like	SOCS box-like	5	3
Spermadhesin, CUB domain	Growth factor receptor domain	5	5
Flavoproteins	Riboflavin synthase domain-like	5	4
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	5	2
Protein kinase-like (PK-like)	P-loop containing nucleoside triphosphate hydrolases	5	5
HMG-box	HMG-box	5	3
GAF domain-like	HD-domain/PDEase-like	5	3
DEATH domain	Caspase-like	5	4
Integrin domains	EGF/Laminin	5	3
vWA-like	Integrin domains	5	3
Fibronectin type III	Protein kinase-like (PK-like)	5	5
PH domain-like	Cysteine-rich domain	5	5
LDL receptor-like module	Growth factor receptor domain	5	5
Galactose-binding domain-like	Growth factor receptor domain	5	5
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	5	3
Spermadhesin, CUB domain	Concanavalin A-like lectins/glucanases	5	5
Plexin repeat	Integrin domains	5	3
Protease propeptides/inhibitors	Zn-dependent exopeptidases	5	2
Cysteine proteinases	DUSP-like	5	5
C-type lectin-like	Galactose-binding domain-like	5	5
ARM repeat	Ankyrin repeat	5	5
Cysteine-rich domain	C2 domain (Calcium/lipid-binding domain, CaLB)	5	4
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	5	4
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	5	5
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	5
Ubiquitin-like	Cysteine proteinases	5	4
Rhodanese/Cell cycle control phosphatase	(Phosphotyrosine protein) phosphatases II	5	1
PH domain-like	EF-hand	5	5
DEATH domain	TPR-like	5	5
PX domain	BAR/IMD domain-like	5	2
Translation proteins	EF-G C-terminal domain-like	5	4
Metalloproteases ("zincins"), catalytic domain	Hemopexin-like domain	5	3
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	5	3
CHY zinc finger-like	Zinc hairpin stack	5	5
Plexin repeat	vWA-like	5	3
Complement control module/SCR domain	Growth factor receptor domain	5	5
PH domain-like	PLC-like phosphodiesterases	5	5
PH domain-like	BEACH domain	5	3
Spectrin repeat	EF-hand	5	5
FYVE/PHD zinc finger	DNase I-like	5	3
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	5	1
(Trans)glycosidases	Chitinase insertion domain	5	1
Voltage-gated potassium channels	E set domains	5	3
ARM repeat	Formin homology 2 domain (FH2 domain)	4	3
Concanavalin A-like lectins/glucanases	P-loop containing nucleoside triphosphate hydrolases	4	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	4	3
WD40 repeat-like	EF-hand	4	4
RING/U-box	UBA-like	4	4
Protein kinase-like (PK-like)	SH3-domain	4	4
P-loop containing nucleoside triphosphate hydrolases	PH domain-like	4	4
CCCH zinc finger	RING/U-box	4	4
Nucleoside diphosphate kinase, NDK	Nucleoside diphosphate kinase, NDK	4	3
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	4	4
PH domain-like	WD40 repeat-like	4	3
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	4	4
PH domain-like	ARM repeat	4	4
Periplasmic binding protein-like I	Periplasmic binding protein-like I	4	4
RCC1/BLIP-II	Hect, E3 ligase catalytic domain	4	4
RING/U-box	P-loop containing nucleoside triphosphate hydrolases	4	3
Phage fibre proteins	Phage fibre proteins	4	3
Snake toxin-like	Protein kinase-like (PK-like)	4	1
Doublecortin (DC)	Doublecortin (DC)	4	4
Clc chloride channel	CBS-domain pair	4	4
Ankyrin repeat	Ankyrin repeat	4	4
Toll/Interleukin receptor TIR domain	Toll/Interleukin receptor TIR domain	4	3
Chromo domain-like	Chromo domain-like	4	3
Ubiquitin-like	Protein kinase-like (PK-like)	4	4
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	4	2
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	4	4
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	cAMP-binding domain-like	4	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipase/lipooxygenase domain (PLAT/LH2 domain)	4	3
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	4	4
BAR/IMD domain-like	PH domain-like	4	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	4	4
TSP-1 type 1 repeat	Voltage-gated potassium channels	4	4
Cysteine proteinases	EF-hand	4	2
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	4	4
Sec7 domain	PH domain-like	4	3
FAD/NAD(P)-binding domain	Folate-binding domain	4	2
TSP type-3 repeat	Concanavalin A-like lectins/glucanases	4	4
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	4	3
SH2 domain	SOCS box-like	4	1
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	4	4
Metalloproteases ("zincins"), catalytic domain	ARM repeat	4	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	4	4
Somatomedin B domain	Family A G protein-coupled receptor-like	4	3
TSP type-3 repeat	TSP type-3 repeat	4	4
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	4	2
ClpP/crotonase	ClpP/crotonase	4	2
Ankyrin repeat	POZ domain	4	4
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	4	1
TPR-like	"Winged helix" DNA-binding domain	4	1
FYVE/PHD zinc finger	Cysteine proteinases	4	3
YWTD domain	YWTD domain	4	4
PR-1-like	PR-1-like	4	4
GINS helical bundle-like	PriA/YqbF domain	4	2
Oxidoreductase molybdopterin-binding domain	E set domains	4	2
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	4	4
FAD-linked reductases, C-terminal domain	Aminomethyltransferase beta-barrel domain	4	2
Protein kinase-like (PK-like)	SAM/Pointed domain	4	3
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	2
Hairpin loop containing domain-like	Hairpin loop containing domain-like	4	4
WD40 repeat-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	4	4
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	4	3
Concanavalin A-like lectins/glucanases	RING/U-box	4	3
Chondroitin AC/alginate lyase	Galactose mutarotase-like	4	3
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	4	3
P-loop containing nucleoside triphosphate hydrolases	Myosin rod fragments	4	4
PH domain-like	Ras GEF	4	4
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	4	1
Cytochrome b5-like heme/steroid binding domain	E set domains	4	2
TB module/8-cys domain	EGF/Laminin	4	4
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	4	4
Spectrin repeat	PH domain-like	4	4
PX domain	SH3-domain	4	3
BAR/IMD domain-like	GTPase activation domain, GAP	4	4
Carbamoyl phosphate synthetase, large subunit connection domain	PreATP-grasp domain	4	4
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	4	2
Nucleotide cyclase	Nucleotide cyclase	4	3
Restriction endonuclease-like	FYVE/PHD zinc finger	4	3
Ubiquitin-like	ARM repeat	4	3
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	4	2
FAD/NAD(P)-binding domain	Aminomethyltransferase beta-barrel domain	4	2
P-loop containing nucleoside triphosphate hydrolases	Ankyrin repeat	4	4
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	4	4
DNase I-like	DNase I-like	4	4
Thioredoxin-like	Ubiquitin-like	4	4
Translation proteins	Ribosomal protein S5 domain 2-like	4	3
Cytochrome b5-like heme/steroid binding domain	Oxidoreductase molybdopterin-binding domain	4	2
ARM repeat	"Winged helix" DNA-binding domain	4	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	4	3
L27 domain	P-loop containing nucleoside triphosphate hydrolases	4	4
Concanavalin A-like lectins/glucanases	Complement control module/SCR domain	4	4
Adhesin YadA, collagen-binding domain	Adhesin YadA, collagen-binding domain	4	1
Myosin S1 fragment, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	4
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	4	4
SH3-domain	SH2 domain	4	4
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	4	4
Frizzled cysteine-rich domain	Frizzled cysteine-rich domain	4	3
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	3
RING/U-box	TPR-like	4	3
Pectin lyase-like	Pectin lyase-like	4	4
SNARE-like	SNARE fusion complex	4	2
Kringle-like	Kringle-like	4	1
FAD-linked reductases, C-terminal domain	Folate-binding domain	4	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	4	4
Immunoglobulin	Protein kinase-like (PK-like)	4	3
PH domain-like	Ankyrin repeat	4	4
Ankyrin repeat	SH3-domain	4	3
SMAD MH1 domain	SMAD/FHA domain	4	2
(Trans)glycosidases	E set domains	4	4
Clavaminate synthase-like	FYVE/PHD zinc finger	4	4
L27 domain	SH3-domain	4	4
Galactose-binding domain-like	Immunoglobulin	4	4
EF-hand	Mitochondrial carrier	4	2
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	4	4
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	3	2
Regulator of G-protein signaling, RGS	PX domain	3	2
p53-like transcription factors	E set domains	3	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	3	3
beta-sandwich domain of Sec23/24	Zn-finger domain of Sec23/24	3	3
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
Protein kinase-like (PK-like)	RCC1/BLIP-II	3	2
Concanavalin A-like lectins/glucanases	SEA domain	3	3
WD40 repeat-like	FYVE/PHD zinc finger	3	2
Single hybrid motif	CoA-dependent acyltransferases	3	1
P-loop containing nucleoside triphosphate hydrolases	FYVE/PHD zinc finger	3	3
L domain-like	Immunoglobulin	3	3
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	3	3
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	3	2
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	3	2
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
Thiolase-like	FabD/lysophospholipase-like	3	1
ARM repeat	Subdomain of clathrin and coatomer appendage domain	3	2
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	3	1
CHY zinc finger-like	RING/U-box	3	3
Protein kinase-like (PK-like)	DEATH domain	3	3
PGBD-like	Hemopexin-like domain	3	2
TPR-like	Clavaminate synthase-like	3	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	3	3
Rudiment single hybrid motif	Aldolase	3	1
RING/U-box	PUA domain-like	3	3
Complement control module/SCR domain	vWA-like	3	3
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	3
vWA-like	Helical domain of Sec23/24	3	3
PH domain-like	Oxysterol-binding protein-like	3	2
Quinoprotein alcohol dehydrogenase-like	Quinoprotein alcohol dehydrogenase-like	3	3
Cysteine-rich domain	GTPase activation domain, GAP	3	3
SAM/Pointed domain	RING/U-box	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	3	3
ArfGap/RecO-like zinc finger	Ankyrin repeat	3	3
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	3	3
Ubiquitin-like	Ras GEF	3	3
Galactose mutarotase-like	(Trans)glycosidases	3	1
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	3	2
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	3	3
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	3	2
Galactose-binding domain-like	alpha/beta-Hydrolases	3	2
EF-hand	Calponin-homology domain, CH-domain	3	3
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	3	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	3	1
RING/U-box	Calcium-dependent phosphotriesterase	3	3
Sec63 N-terminal domain-like	E set domains	3	2
vWA-like	Integrin beta tail domain	3	2
beta-N-acetylhexosaminidase-like domain	E set domains	3	3
Immunoglobulin	Spermadhesin, CUB domain	3	3
Protein kinase-like (PK-like)	Polo-box domain	3	2
NagB/RpiA/CoA transferase-like	NagB/RpiA/CoA transferase-like	3	2
Galactose-binding domain-like	Protein kinase-like (PK-like)	3	3
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	3	3
Aldolase	post-HMGL domain-like	3	1
SNARE fusion complex	SNARE fusion complex	3	2
PreATP-grasp domain	Aldolase	3	1
UBC-like	RING/U-box	3	2
vWA-like	Concanavalin A-like lectins/glucanases	3	3
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	3	2
Galactose mutarotase-like	Glycosyl hydrolase domain	3	1
Glucocorticoid receptor-like (DNA-binding domain)	SH3-domain	3	1
Acetyl-CoA synthetase-like	Acetyl-CoA synthetase-like	3	3
Calpain large subunit, middle domain (domain III)	EF-hand	3	1
Cysteine-rich domain	Ubiquitin-like	3	3
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	3	1
Nucleic acid-binding proteins	Translation proteins SH3-like domain	3	2
Elafin-like	Elafin-like	3	3
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	3	2
EGF/Laminin	C-type lectin-like	3	3
Nucleotide-binding domain	Nucleotide-binding domain	3	2
Concanavalin A-like lectins/glucanases	SRCR-like	3	3
alpha-catenin/vinculin-like	alpha-catenin/vinculin-like	3	3
Aldolase	Single hybrid motif	3	1
Actin depolymerizing proteins	VHP, Villin headpiece domain	3	3
Complement control module/SCR domain	Immunoglobulin	3	3
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	3	2
TPR-like	HIT/MYND zinc finger-like	3	3
Cytidine deaminase-like	Cytidine deaminase-like	3	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	3	3
P-loop containing nucleoside triphosphate hydrolases	POZ domain	3	1
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	3	2
Ribonuclease H-like	Ribonuclease H-like	3	2
FYVE/PHD zinc finger	"Winged helix" DNA-binding domain	3	3
Amine oxidase N-terminal region	Amine oxidase catalytic domain	3	2
Ribonuclease H-like	RuvA domain 2-like	3	3
Zn-finger domain of Sec23/24	vWA-like	3	3
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	3	3
TSP-1 type 1 repeat	EGF/Laminin	3	3
Rudiment single hybrid motif	post-HMGL domain-like	3	1
Ubiquitin-like	RING/U-box	3	3
Retrovirus zinc finger-like domains	P-loop containing nucleoside triphosphate hydrolases	3	3
PYP-like sensor domain (PAS domain)	cAMP-binding domain-like	3	2
Fibronectin type III	SEA domain	3	3
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	3	1
FKBP-like	EF-hand	3	1
RING/U-box	Fibronectin type III	3	2
Bromodomain	Bromodomain	3	3
Translation proteins	Translation proteins	3	2
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
Nucleotidylyl transferase	P-loop containing nucleoside triphosphate hydrolases	3	3
Glutathione synthetase ATP-binding domain-like	post-HMGL domain-like	3	1
Calponin-homology domain, CH-domain	E set domains	3	3
beta-sandwich domain of Sec23/24	vWA-like	3	3
EGF/Laminin	Integrin beta tail domain	3	2
Immunoglobulin	Family A G protein-coupled receptor-like	3	3
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	3	1
WD40 repeat-like	TPR-like	3	3
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	3	3
Zinc hairpin stack	RING/U-box	3	3
UBA-like	UBA-like	3	3
Saposin	Saposin	3	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	3	3
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	3	3
Translation proteins	Initiation factor IF2/eIF5b, domain 3	3	2
MgtE N-terminal domain-like	MgtE N-terminal domain-like	3	3
B-box zinc-binding domain	Fibronectin type III	3	2
Amine oxidase N-terminal region	Amine oxidase N-terminal region	3	2
RCC1/BLIP-II	RCC1/BLIP-II	3	3
Thiolase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	3	1
Calponin-homology domain, CH-domain	Calponin-homology domain, CH-domain	3	3
Homeodomain-like	RING/U-box	3	3
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	3	3
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	3	3
TPR-like	ARM repeat	3	3
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	3	2
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	3	3
SNF-like	SNF-like	3	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	3	3
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	3	1
Growth factor receptor domain	SEA domain	3	2
Integrin domains	Integrin beta tail domain	3	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	2
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	3	2
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	3	1
SGNH hydrolase	DNase I-like	3	2
Zinc beta-ribbon	Cyclin-like	3	3
Galactose-binding domain-like	vWA-like	3	3
Cap-Gly domain	Cysteine proteinases	3	2
SH3-domain	GTPase activation domain, GAP	3	3
P-loop containing nucleoside triphosphate hydrolases	TGS-like	3	1
ARM repeat	Concanavalin A-like lectins/glucanases	3	3
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	Multidrug efflux transporter AcrB transmembrane domain	3	2
Protein kinase-like (PK-like)	WD40 repeat-like	3	3
FnI-like domain	FnI-like domain	3	3
Aconitase iron-sulfur domain	LeuD/IlvD-like	3	1
FKBP-like	TPR-like	3	3
ARM repeat	Cysteine proteinases	3	3
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	3	2
PreATP-grasp domain	post-HMGL domain-like	3	1
Guanido kinase N-terminal domain	Guanido kinase N-terminal domain	3	2
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	3	1
PurM N-terminal domain-like	PurM C-terminal domain-like	3	3
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	3	1
E set domains	Cysteine proteinases	3	2
ARM repeat	Clathrin adaptor appendage domain	3	2
Nucleic acid-binding proteins	Eukaryotic type KH-domain (KH-domain type I)	3	3
PreATP-grasp domain	Methylglyoxal synthase-like	3	3
EF-hand	RING/U-box	3	3
Glutamine synthetase/guanido kinase	Glutamine synthetase/guanido kinase	3	2
HIT/MYND zinc finger-like	SET domain	3	3
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	3	2
Toll/Interleukin receptor TIR domain	SAM/Pointed domain	3	2
SEA domain	Galactose-binding domain-like	3	3
Formyltransferase	FMT C-terminal domain-like	3	2
Glutathione synthetase ATP-binding domain-like	Aldolase	3	1
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	3	3
CCCH zinc finger	CCCH zinc finger	3	3
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	3	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	3	3
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	3	3
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Nucleotidyltransferase substrate binding subunit/domain	3	3
Ubiquitin-like	Ankyrin repeat	3	3
Galactose-binding domain-like	Hect, E3 ligase catalytic domain	3	3
FYVE/PHD zinc finger	RING/U-box	3	3
FYVE/PHD zinc finger	Tudor/PWWP/MBT	3	3
PYP-like sensor domain (PAS domain)	Voltage-gated potassium channels	3	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	3	3
Plexin repeat	Integrin beta tail domain	3	2
ENTH/VHS domain	GAT-like domain	3	2
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	3	1
post-HMGL domain-like	Single hybrid motif	3	1
Nucleotidylyl transferase	Ribosomal protein L25-like	2	2
Thioredoxin-like	beta-beta-alpha zinc fingers	2	2
ALDH-like	ALDH-like	2	1
cAMP-binding domain-like	Ras GEF	2	2
F-box domain	Sec7 domain	2	1
Ypt/Rab-GAP domain of gyp1p	Rhodanese/Cell cycle control phosphatase	2	2
UBA-like	Hect, E3 ligase catalytic domain	2	2
WD40 repeat-like	Cyclophilin-like	2	1
Granulin repeat	Granulin repeat	2	2
C2 domain (Calcium/lipid-binding domain, CaLB)	FabD/lysophospholipase-like	2	2
PH domain-like	Moesin tail domain	2	1
Carbohydrate-binding domain	(Trans)glycosidases	2	2
PX domain	Outer arm dynein light chain 1	2	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	2
RNA-binding domain, RBD	Cyclophilin-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	2	1
CAD & PB1 domains	UBA-like	2	2
HlyD-like secretion proteins	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	2	2
RuvA domain 2-like	Nucleic acid-binding proteins	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	2	2
SAM/Pointed domain	HD-domain/PDEase-like	2	2
LDL receptor-like module	Spermadhesin, CUB domain	2	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	2
Calponin-homology domain, CH-domain	DBL homology domain (DH-domain)	2	2
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	2	2
Class I glutamine amidotransferase-like	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
cAMP-binding domain-like	Protein kinase-like (PK-like)	2	2
Metallo-dependent phosphatases	Metallo-dependent phosphatases	2	1
"Winged helix" DNA-binding domain	PDZ domain-like	2	2
Trypsin-like serine proteases	PDZ domain-like	2	2
EF-hand	Cysteine-rich domain	2	2
TATA-box binding protein-like	DNA-glycosylase	2	1
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	2	2
P-loop containing nucleoside triphosphate hydrolases	WD40 repeat-like	2	2
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Metallo-dependent hydrolases	2	2
Glutaminase/Asparaginase	Ankyrin repeat	2	1
B-box zinc-binding domain	Calcium-dependent phosphotriesterase	2	2
cAMP-binding domain-like	Ubiquitin-like	2	2
FLJ32549 domain-like	FLJ32549 domain-like	2	1
"Winged helix" DNA-binding domain	Ubiquitin-like	2	2
Ubiquitin-like	SH2 domain	2	2
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	2
RNI-like	Ubiquitin-like	2	2
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	2	2
FAS1 domain	EGF/Laminin	2	2
R3H domain	Ribonuclease H-like	2	2
SH3-domain	EF-hand	2	2
Nucleic acid-binding proteins	TPR-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Microbial and mitochondrial ADK, insert "zinc finger" domain	2	2
Kelch motif	EGF/Laminin	2	2
Glutathione synthetase ATP-binding domain-like	Metallo-dependent hydrolases	2	2
C-type lectin-like	Hairpin loop containing domain-like	2	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	2	2
Carbohydrate-binding domain	E set domains	2	2
WW domain	EF-hand	2	2
HMA, heavy metal-associated domain	HAD-like	2	2
Concanavalin A-like lectins/glucanases	Voltage-gated potassium channels	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	2	2
SRCR-like	L domain-like	2	2
E set domains	Calcium-dependent phosphotriesterase	2	2
Voltage-gated potassium channels	EF-hand	2	2
Tropomyosin	Tropomyosin	2	2
Regulator of G-protein signaling, RGS	Regulator of G-protein signaling, RGS	2	2
PsbU/PolX domain-like	Nucleotidyltransferase	2	2
PH domain-like	"Winged helix" DNA-binding domain	2	2
RNA-binding domain, RBD	UBA-like	2	2
beta-lactamase/transpeptidase-like	beta-lactamase/transpeptidase-like	2	2
P-loop containing nucleoside triphosphate hydrolases	R3H domain	2	2
NHL repeat	WD40 repeat-like	2	2
Polo-box domain	Polo-box domain	2	1
Mib/herc2 domain-like	RING/U-box	2	2
Ankyrin repeat	RING/U-box	2	1
L domain-like	RNI-like	2	2
MOSC N-terminal domain-like	PK beta-barrel domain-like	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	2	1
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Glutathione synthetase ATP-binding domain-like	2	2
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	2	2
SH2 domain	GTPase activation domain, GAP	2	2
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	2	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	2	1
P-loop containing nucleoside triphosphate hydrolases	ARM repeat	2	2
Protein kinase-like (PK-like)	MIT domain	2	2
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	2	2
NAD(P)-binding Rossmann-fold domains	SCP-like	2	2
Galactose-binding domain-like	Kringle-like	2	2
PH domain-like	RUN domain-like	2	2
FYVE/PHD zinc finger	Family A G protein-coupled receptor-like	2	2
L domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
DBL homology domain (DH-domain)	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Second domain of FERM	Moesin tail domain	2	1
Galactose-binding domain-like	Galactose mutarotase-like	2	2
Ubiquitin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Methylglyoxal synthase-like	Composite domain of metallo-dependent hydrolases	2	2
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	2	2
Taf5 N-terminal domain-like	WD40 repeat-like	2	2
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	2	2
Class I glutamine amidotransferase-like	PreATP-grasp domain	2	2
Tropomyosin	Smc hinge domain	2	2
Ubiquitin-like	Moesin tail domain	2	1
Ribosomal L27 protein-like	Nucleic acid-binding proteins	2	2
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	2	2
Carbamate kinase-like	ALDH-like	2	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	2	1
Growth factor receptor domain	Cadherin-like	2	2
CRAL/TRIO domain	DBL homology domain (DH-domain)	2	2
Spermadhesin, CUB domain	Kelch motif	2	2
UBC-like	UBA-like	2	2
RCC1/BLIP-II	POZ domain	2	2
Second domain of FERM	RING/U-box	2	2
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	2	2
RNase III domain-like	dsRNA-binding domain-like	2	2
EGF/Laminin	Trypsin-like serine proteases	2	2
Formate/glycerate dehydrogenase catalytic domain-like	DHS-like NAD/FAD-binding domain	2	1
Pentapeptide repeat-like	Mitochondrial carrier	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	PUA domain-like	2	2
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	2	2
PH domain-like	Protein kinase-like (PK-like)	2	2
TNF receptor-like	DEATH domain	2	1
Cadherin-like	Dystroglycan, domain 2	2	2
Homodimeric domain of signal transducing histidine kinase	CheY-like	2	2
Tropomyosin	P-loop containing nucleoside triphosphate hydrolases	2	2
alpha-helical ferredoxin	FMN-linked oxidoreductases	2	2
Enolase N-terminal domain-like	Enolase C-terminal domain-like	2	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	CBS-domain pair	2	1
Trefoil	Trefoil	2	2
PLP-binding barrel	Alanine racemase C-terminal domain-like	2	1
Immunoglobulin	Toll/Interleukin receptor TIR domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Carbamoyl phosphate synthetase, large subunit connection domain	2	2
P-loop containing nucleoside triphosphate hydrolases	CarD-like	2	2
ARM repeat	Hect, E3 ligase catalytic domain	2	2
Chaperone J-domain	RNA-binding domain, RBD	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	2	2
EGF/Laminin	Lipase/lipooxygenase domain (PLAT/LH2 domain)	2	2
Galactose-binding domain-like	TSP-1 type 1 repeat	2	2
Phosphoenolpyruvate/pyruvate domain	Thioesterase/thiol ester dehydrase-isomerase	2	2
Galactose-binding domain-like	Complement control module/SCR domain	2	2
F-box domain	Pectin lyase-like	2	2
Growth factor receptor domain	Fibrinogen C-terminal domain-like	2	2
TB module/8-cys domain	Growth factor receptor domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Second domain of FERM	2	2
Galactose oxidase, central domain	Galactose oxidase, central domain	2	2
Methylglyoxal synthase-like	Metallo-dependent hydrolases	2	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	2	1
Concanavalin A-like lectins/glucanases	LDL receptor-like module	2	2
PreATP-grasp domain	Composite domain of metallo-dependent hydrolases	2	2
Protein kinase-like (PK-like)	KA1-like	2	2
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	2	2
alpha-helical ferredoxin	Nucleotide-binding domain	2	2
FLJ32549 domain-like	FLJ32549 C-terminal domain-like	2	1
DEATH domain	Immunoglobulin	2	2
Integrin domains	Integrin domains	2	2
EGF/Laminin	Fibronectin type III	2	2
CAD & PB1 domains	Protein kinase-like (PK-like)	2	2
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	1
MurCD N-terminal domain	MurD-like peptide ligases, catalytic domain	2	2
Growth factor receptor domain	Mannose 6-phosphate receptor domain	2	2
Methylglyoxal synthase-like	Cytidine deaminase-like	2	2
CalX-like	Concanavalin A-like lectins/glucanases	2	2
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	2	2
Immunoglobulin	TSP-1 type 1 repeat	2	2
Galactose-binding domain-like	Chondroitin AC/alginate lyase	2	2
Homeodomain-like	FAD-linked reductases, C-terminal domain	2	2
Ankyrin repeat	Ras GEF	2	2
Barwin-like endoglucanases	Invertebrate chitin-binding proteins	2	2
RNA-binding domain, RBD	dsRNA-binding domain-like	2	2
CheY-like	C-terminal effector domain of the bipartite response regulators	2	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	2	2
Carbamoyl phosphate synthetase, small subunit N-terminal domain	PreATP-grasp domain	2	2
POZ domain	TRAF domain-like	2	2
PDZ domain-like	Second domain of FERM	2	2
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	2	1
Nucleotide-binding domain	FMN-linked oxidoreductases	2	2
Metalloproteases ("zincins"), catalytic domain	EGF/Laminin	2	2
RNA-binding domain, RBD	L domain-like	2	2
GTPase activation domain, GAP	RGC domain-like	2	2
Ankyrin repeat	Protein kinase-like (PK-like)	2	2
Nucleotide-binding domain	FAD-linked reductases, C-terminal domain	2	2
Sec7 domain	ARM repeat	2	2
CBD9-like	PHM/PNGase F	2	1
Concanavalin A-like lectins/glucanases	TSP-1 type 1 repeat	2	2
Tex N-terminal region-like	Ribonuclease H-like	2	2
SAM/Pointed domain	PH domain-like	2	2
Periplasmic binding protein-like II	MetI-like	2	2
WWE domain	Hect, E3 ligase catalytic domain	2	2
Restriction endonuclease-like	RuvA domain 2-like	2	2
Spermadhesin, CUB domain	Galactose-binding domain-like	2	2
P-loop containing nucleoside triphosphate hydrolases	E set domains	2	1
Integrin alpha N-terminal domain	Integrin domains	2	2
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	2	1
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	2	2
PreATP-grasp domain	PreATP-grasp domain	2	2
C-type lectin-like	Family A G protein-coupled receptor-like	2	1
Nucleotidylyl transferase	S15/NS1 RNA-binding domain	2	2
Ribonuclease H-like	Nucleic acid-binding proteins	2	2
BRCT domain	Homeodomain-like	2	2
MIR domain	MIR domain	2	2
Acetyl-CoA synthetase-like	ACP-like	2	2
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	2	1
CheY-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Growth factor receptor domain	Fibronectin type III	2	2
Phage tail proteins	Phage tail proteins	2	2
S15/NS1 RNA-binding domain	Class II aaRS and biotin synthetases	2	2
BAR/IMD domain-like	Cysteine-rich domain	2	2
Inosine monophosphate dehydrogenase (IMPDH)	Inosine monophosphate dehydrogenase (IMPDH)	2	1
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	2	2
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	WW domain	2	2
Immunoglobulin	Caspase-like	2	2
ARM repeat	Toll/Interleukin receptor TIR domain	2	2
CRAL/TRIO domain	PH domain-like	2	2
Protein kinase-like (PK-like)	UBA-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	2	1
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
Kringle-like	Protein kinase-like (PK-like)	2	2
Regulator of G-protein signaling, RGS	Protein kinase-like (PK-like)	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	PX domain	2	2
Cytokine	Cytokine	2	2
B-box zinc-binding domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Immunoglobulin	tRNA-intron endonuclease catalytic domain-like	2	2
DBL homology domain (DH-domain)	Ubiquitin-like	2	2
Mannose 6-phosphate receptor domain	Mannose 6-phosphate receptor domain	2	2
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	2	1
Translational machinery components	L30e-like	2	2
Zinc beta-ribbon	Zinc beta-ribbon	2	1
Immunoglobulin	DNase I-like	2	2
PABC (PABP) domain	PABC (PABP) domain	2	2
ARID-like	Clavaminate synthase-like	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	2	2
F-box domain	L domain-like	2	2
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	2	2
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	2	2
Immunoglobulin	Concanavalin A-like lectins/glucanases	2	2
MIR domain	IP3 receptor type 1 binding core, domain 2	2	2
Family A G protein-coupled receptor-like	DNase I-like	2	2
DEATH domain	Toll/Interleukin receptor TIR domain	2	2
Lipovitellin-phosvitin complex, superhelical domain	Lipovitellin-phosvitin complex; beta-sheet shell regions	2	2
Carbamoyl phosphate synthetase, large subunit connection domain	Composite domain of metallo-dependent hydrolases	2	2
Galactose-binding domain-like	Mib/herc2 domain-like	2	2
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	2	2
Glutathione synthetase ATP-binding domain-like	Composite domain of metallo-dependent hydrolases	2	2
DBL homology domain (DH-domain)	WD40 repeat-like	2	2
Chaperone J-domain	Thioredoxin-like	2	2
"Winged helix" DNA-binding domain	E set domains	2	1
Homeodomain-like	FAD/NAD(P)-binding domain	2	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	2	2
Cap-Gly domain	Cap-Gly domain	2	2
NAD(P)-binding Rossmann-fold domains	DHS-like NAD/FAD-binding domain	2	1
A DNA-binding domain in eukaryotic transcription factors	Leucine zipper domain	2	2
Mib/herc2 domain-like	Hect, E3 ligase catalytic domain	2	2
Spectrin repeat	DBL homology domain (DH-domain)	2	2
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	2	1
PDZ domain-like	WW domain	2	2
Quinoprotein alcohol dehydrogenase-like	Protein kinase-like (PK-like)	2	2
Eukaryotic type KH-domain (KH-domain type I)	Tudor/PWWP/MBT	2	2
Spectrin repeat	SH3-domain	2	2
Carbohydrate-binding domain	beta-N-acetylhexosaminidase-like domain	2	2
E set domains	Pectin lyase-like	2	2
Thioredoxin-like	ERP29 C domain-like	2	1
SH2 domain	C2 domain (Calcium/lipid-binding domain, CaLB)	2	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	2	2
Globin-like	Globin-like	2	2
Calponin-homology domain, CH-domain	PH domain-like	2	2
Class II aaRS and biotin synthetases	ThrRS/AlaRS common domain	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	2	2
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	2	1
Protein kinase-like (PK-like)	NTF2-like	2	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	2	2
Second domain of FERM	Second domain of FERM	2	2
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	2	2
CRAL/TRIO domain	Spectrin repeat	2	2
ADC-like	Cdc48 domain 2-like	2	1
RuvA domain 2-like	RuvA domain 2-like	2	2
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	2	2
Metalloproteases ("zincins"), catalytic domain	Spermadhesin, CUB domain	2	2
TPR-like	SET domain	2	2
CAD & PB1 domains	RING/U-box	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	1
TB module/8-cys domain	TB module/8-cys domain	2	2
PreATP-grasp domain	Metallo-dependent hydrolases	2	2
TRAF domain-like	WD40 repeat-like	2	2
WW domain	Hect, E3 ligase catalytic domain	2	2
SAP domain	Restriction endonuclease-like	2	1
Tudor/PWWP/MBT	P-loop containing nucleoside triphosphate hydrolases	2	2
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	2	2
Hedgehog/DD-peptidase	Hedgehog/intein (Hint) domain	2	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	2	2
Tex N-terminal region-like	Nucleic acid-binding proteins	2	2
Restriction endonuclease-like	Cysteine proteinases	2	1
Frizzled cysteine-rich domain	TIMP-like	2	1
DBL homology domain (DH-domain)	GTPase activation domain, GAP	2	2
C-type lectin-like	SEA domain	2	2
Ypt/Rab-GAP domain of gyp1p	RUN domain-like	2	2
HCP-like	HCP-like	2	2
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	2	2
WGR domain-like	ADP-ribosylation	2	2
UBA-like	Cysteine proteinases	2	2
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	2	2
Immunoglobulin	EGF/Laminin	2	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	2	2
Chaperone J-domain	Homeodomain-like	2	1
Terpenoid cyclases/Protein prenyltransferases	Alpha-macroglobulin receptor domain	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	2	2
Phospholipase D/nuclease	Phospholipase D/nuclease	2	2
Growth factor receptor domain	SRCR-like	2	2
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	2	1
S15/NS1 RNA-binding domain	Class II aaRS ABD-related	2	2
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	2	1
ADC-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Tex N-terminal region-like	RuvA domain 2-like	2	2
Calponin-homology domain, CH-domain	GAS2 domain-like	2	1
Methyl-accepting chemotaxis protein (MCP) signaling domain	Methyl-accepting chemotaxis protein (MCP) signaling domain	2	2
Complement control module/SCR domain	Trypsin-like serine proteases	2	2
Myosin rod fragments	Myosin rod fragments	2	2
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	2	1
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	2	1
lambda integrase-like, N-terminal domain	DNA breaking-rejoining enzymes	2	2
Class I glutamine amidotransferase-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	2	1
ARM repeat	L domain-like	2	2
NAD(P)-binding Rossmann-fold domains	P-loop containing nucleoside triphosphate hydrolases	2	2
Thyroglobulin type-1 domain	EF-hand	2	2
Translation proteins	ThrRS/AlaRS common domain	2	2
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	2	2
Ankyrin repeat	SAM/Pointed domain	2	2
B-box zinc-binding domain	Concanavalin A-like lectins/glucanases	2	1
C-type lectin-like	Immunoglobulin	2	2
Barwin-like endoglucanases	Barwin-like endoglucanases	2	2
Class I glutamine amidotransferase-like	Glutathione synthetase ATP-binding domain-like	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
cAMP-binding domain-like	"Winged helix" DNA-binding domain	2	2
Family A G protein-coupled receptor-like	alpha/beta-Hydrolases	2	2
Metalloproteases ("zincins"), catalytic domain	Fibronectin type III	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	2	2
SMAD/FHA domain	SMAD/FHA domain	2	2
Sema domain	Plexin repeat	2	2
Protein kinase-like (PK-like)	PX domain	2	2
EGF/Laminin	(Trans)glycosidases	2	2
F-box domain	Concanavalin A-like lectins/glucanases	2	2
Cysteine proteinases	Cysteine proteinases	2	2
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	2	1
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	2	2
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	1
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Ubiquitin-like	Ran binding protein zinc finger-like	2	2
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	2	2
Cupredoxins	Nucleotide cyclase	1	1
GAF domain-like	Phosphoglucomutase, first 3 domains	1	1
SAP domain	RNA-binding domain, RBD	1	1
FAD/NAD(P)-binding domain	Calponin-homology domain, CH-domain	1	1
F-box domain	Voltage-gated potassium channels	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
L30e-like	alpha/beta knot	1	1
C-type lectin-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Methylglyoxal synthase-like	1	1
His-Me finger endonucleases	DNA/RNA polymerases	1	1
Spermadhesin, CUB domain	Cadherin-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	YebC-like	1	1
Chromo domain-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Ankyrin repeat	PDZ domain-like	1	1
G protein-binding domain	FYVE/PHD zinc finger	1	1
FMN-linked oxidoreductases	dsRNA-binding domain-like	1	1
L21p-like	L21p-like	1	1
Ubiquitin-like	NAD kinase/diacylglycerol kinase-like	1	1
Kelch motif	SH3-domain	1	1
PDZ domain-like	Ras GEF	1	1
CRAL/TRIO domain	GTPase activation domain, GAP	1	1
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	1	1
DBL homology domain (DH-domain)	SGNH hydrolase	1	1
Trefoil	LDL receptor-like module	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
MgtE membrane domain-like	MgtE membrane domain-like	1	1
Family A G protein-coupled receptor-like	beta-lactamase/transpeptidase-like	1	1
MFS general substrate transporter	Ribulose-phoshate binding barrel	1	1
MIT domain	Calpain large subunit, middle domain (domain III)	1	1
Methylated DNA-protein cysteine methyltransferase domain	Methylated DNA-protein cysteine methyltransferase, C-terminal domain	1	1
Amyloid beta a4 protein copper binding domain (domain 2)	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
vWA-like	Cysteine-rich domain	1	1
Thioredoxin-like	DnaJ/Hsp40 cysteine-rich domain	1	1
Macro domain-like	Zn-dependent exopeptidases	1	1
RUN domain-like	PDZ domain-like	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
PLP-dependent transferases	PreATP-grasp domain	1	1
Retrovirus zinc finger-like domains	PAP/OAS1 substrate-binding domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Smc hinge domain	1	1
RING/U-box	Protein kinase-like (PK-like)	1	1
FabD/lysophospholipase-like	EF-hand	1	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Homeodomain-like	EAL domain-like	1	1
Actin-like ATPase domain	AF1104-like	1	1
Outer arm dynein light chain 1	WD40 repeat-like	1	1
Hairpin loop containing domain-like	SNARE-like	1	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	1	1
Family A G protein-coupled receptor-like	ABC transporter transmembrane region	1	1
Fibronectin type III	CalX-like	1	1
ARM repeat	FYVE/PHD zinc finger	1	1
Homocysteine S-methyltransferase	Methionine synthase activation domain-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain II	1	1
Cytochrome b5-like heme/steroid binding domain	Hect, E3 ligase catalytic domain	1	1
tRNA-guanine transglycosylase	tRNA-guanine transglycosylase	1	1
Trefoil	Concanavalin A-like lectins/glucanases	1	1
PH domain-like	Ypt/Rab-GAP domain of gyp1p	1	1
Nucleotidylyl transferase	C-terminal domain of ProRS	1	1
RuvA domain 2-like	WD40 repeat-like	1	1
EF-hand	GAS2 domain-like	1	1
Fibronectin type III	Ankyrin repeat	1	1
Ubiquitin-like	BAG domain	1	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	1	1
TPR-like	HSP20-like chaperones	1	1
TPR-like	Immunoglobulin	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Methylglyoxal synthase-like	Aspartate/ornithine carbamoyltransferase	1	1
SRCR-like	EGF/Laminin	1	1
MetI-like	MetI-like	1	1
RUN domain-like	RUN domain-like	1	1
XRCC4, N-terminal domain	DNase I-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Immunoglobulin	LDL receptor-like module	1	1
E2F-DP heterodimerization region	Alkaline phosphatase-like	1	1
Ubiquitin-like	PUA domain-like	1	1
DEATH domain	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
RNA-binding domain, RBD	NTF2-like	1	1
PH domain-like	BSD domain-like	1	1
Porins	Carboxypeptidase regulatory domain-like	1	1
Concanavalin A-like lectins/glucanases	L domain-like	1	1
Fibronectin type III	Anthrax protective antigen	1	1
EGF/Laminin	DEK C-terminal domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Metallo-dependent hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Molybdenum cofactor biosynthesis proteins	MoeA N-terminal region -like	1	1
Family A G protein-coupled receptor-like	POZ domain	1	1
AbfB domain	Kringle-like	1	1
SRCR-like	LDL receptor-like module	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
SAP domain	DNase I-like	1	1
Actin-like ATPase domain	CV3147-like	1	1
ARM repeat	beta-sandwich domain of Sec23/24	1	1
ISP domain	Ferritin-like	1	1
ARM repeat	POZ domain	1	1
Glutathione synthetase ATP-binding domain-like	Citrate synthase	1	1
UBC-like	Endosomal sorting complex assembly domain	1	1
RING/U-box	PDZ domain-like	1	1
PDZ domain-like	Formin homology 2 domain (FH2 domain)	1	1
Apolipoprotein A-I	E set domains	1	1
WD40 repeat-like	Ribonuclease H-like	1	1
WWE domain	ADP-ribosylation	1	1
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	1	1
ADP-ribosylation	vWA-like	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
GST C-terminal domain-like	GST C-terminal domain-like	1	1
Homeodomain-like	JAB1/MPN domain	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
ARM repeat	Tudor/PWWP/MBT	1	1
RuvA domain 2-like	Pentapeptide repeat-like	1	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
FF domain	GTPase activation domain, GAP	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	1	1
(Trans)glycosidases	(Trans)glycosidases	1	1
Tudor/PWWP/MBT	Hect, E3 ligase catalytic domain	1	1
Thioredoxin-like	NHL repeat	1	1
Six-hairpin glycosidases	P-loop containing nucleoside triphosphate hydrolases	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	1	1
Chaperone J-domain	Nucleotidyltransferase substrate binding subunit/domain	1	1
G protein-binding domain	PH domain-like	1	1
BRCT domain	PH domain-like	1	1
PGBD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
ThrRS/AlaRS common domain	Class II aaRS ABD-related	1	1
Tricorn protease domain 2	DPP6 N-terminal domain-like	1	1
RING/U-box	ARM repeat	1	1
Thioredoxin-like	eEF1-gamma domain	1	1
PK beta-barrel domain-like	PK C-terminal domain-like	1	1
FYVE/PHD zinc finger	SMAD/FHA domain	1	1
I/LWEQ domain	I/LWEQ domain	1	1
PGBD-like	PGBD-like	1	1
PH domain-like	Glycolipid transfer protein, GLTP	1	1
DEATH domain	WD40 repeat-like	1	1
CCCH zinc finger	RNA-binding domain, RBD	1	1
L domain-like	Protein kinase-like (PK-like)	1	1
Concanavalin A-like lectins/glucanases	Ricin B-like lectins	1	1
WW domain	NAD(P)-binding Rossmann-fold domains	1	1
Fibronectin type III	Thioredoxin-like	1	1
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	1	1
vWA-like	Cysteine proteinases	1	1
Lipoxigenase	Lipoxigenase	1	1
PurS-like	PurM N-terminal domain-like	1	1
F-box domain	HCP-like	1	1
FYVE/PHD zinc finger	SET domain	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	1	1
N-terminal domain of MutM-like DNA repair proteins	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
BRCT domain	Domain of poly(ADP-ribose) polymerase	1	1
Tricorn protease domain 2	TPR-like	1	1
Cullin repeat-like	Cullin repeat-like	1	1
NAD(P)-binding Rossmann-fold domains	NagB/RpiA/CoA transferase-like	1	1
RNI-like	Concanavalin A-like lectins/glucanases	1	1
CRAL/TRIO domain	PapD-like	1	1
Tudor/PWWP/MBT	SET domain	1	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	1	1
WD40 repeat-like	RCC1/BLIP-II	1	1
NTF2-like	UBA-like	1	1
PLP-dependent transferases	Glutathione synthetase ATP-binding domain-like	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
C-terminal, gelsolin-like domain of Sec23/24	Actin depolymerizing proteins	1	1
Dehydroquinate synthase-like	LysM domain	1	1
GYF domain	ARM repeat	1	1
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	VPS9 domain	1	1
Elafin-like	Immunoglobulin	1	1
TPR-like	MgtE membrane domain-like	1	1
FYVE/PHD zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	1	1
SPOC domain-like	SAP domain	1	1
TPR-like	TSP type-3 repeat	1	1
Voltage-gated potassium channels	Pentapeptide repeat-like	1	1
Complement control module/SCR domain	C-type lectin-like	1	1
Methionine synthase domain	Methionine synthase activation domain-like	1	1
G protein-binding domain	G protein-binding domain	1	1
A middle domain of Talin 1	alpha-catenin/vinculin-like	1	1
YWTD domain	Fibronectin type III	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
TSP-1 type 1 repeat	DEATH domain	1	1
Ankyrin repeat	HIT/MYND zinc finger-like	1	1
Cysteine proteinases	HIT/MYND zinc finger-like	1	1
Concanavalin A-like lectins/glucanases	FnI-like domain	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Type II DNA topoisomerase	1	1
Thioesterase/thiol ester dehydrase-isomerase	SCP-like	1	1
Formyltransferase	ACP-like	1	1
Adhesin YadA, collagen-binding domain	Tropomyosin	1	1
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	EGF/Laminin	1	1
Clc chloride channel	Clc chloride channel	1	1
ENTH/VHS domain	SH3-domain	1	1
Radical SAM enzymes	Molybdenum cofactor biosynthesis protein C, MoaC	1	1
SEA domain	Voltage-gated potassium channels	1	1
Ubiquitin-like	alpha-catenin/vinculin-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	1	1
F-box domain	SMI1/KNR4-like	1	1
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	1	1
Immunoglobulin	Hairpin loop containing domain-like	1	1
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	1	1
Adenine nucleotide alpha hydrolases-like	Type II DNA topoisomerase	1	1
Thioredoxin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Kix domain of CBP (creb binding protein)	Bromodomain	1	1
Nitrite/Sulfite reductase N-terminal domain-like	CbiG N-terminal domain-like	1	1
Sema domain	TSP-1 type 1 repeat	1	1
Kix domain of CBP (creb binding protein)	RING/U-box	1	1
NagB/RpiA/CoA transferase-like	alpha-helical ferredoxin	1	1
FMT C-terminal domain-like	ACP-like	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	ACT-like	1	1
Pectin lyase-like	Tudor/PWWP/MBT	1	1
Pentein	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	1	1
PreATP-grasp domain	PurM N-terminal domain-like	1	1
Caspase-like	Caspase-like	1	1
ACP-like	ALDH-like	1	1
F-box domain	YccV-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Nucleic acid-binding proteins	1	1
Precorrin-8X methylmutase CbiC/CobH	CbiG N-terminal domain-like	1	1
Protease propeptides/inhibitors	Protease propeptides/inhibitors	1	1
Anthrax protective antigen	Family A G protein-coupled receptor-like	1	1
UBA-like	DNase I-like	1	1
Restriction endonuclease-like	SWIB/MDM2 domain	1	1
Actin-like ATPase domain	CheY-like	1	1
"Winged helix" DNA-binding domain	SAICAR synthase-like	1	1
Concanavalin A-like lectins/glucanases	DNase I-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Nucleotidyltransferase	1	1
Rap/Ran-GAP	PDZ domain-like	1	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
TPR-like	Ankyrin repeat	1	1
RNA-binding domain, RBD	TSP-1 type 1 repeat	1	1
P-loop containing nucleoside triphosphate hydrolases	Fibrinogen C-terminal domain-like	1	1
A heparin-binding domain	Amyloid beta a4 protein copper binding domain (domain 2)	1	1
EGF/Laminin	SEA domain	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
Cupredoxins	EAL domain-like	1	1
Pseudouridine synthase	PUA domain-like	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
Second domain of FERM	(Phosphotyrosine protein) phosphatases II	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
RNA-binding domain, RBD	Cysteine proteinases	1	1
L domain-like	RING/U-box	1	1
PUA domain-like	eIF1-like	1	1
P-loop containing nucleoside triphosphate hydrolases	FF domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
HAD-like	Protein kinase-like (PK-like)	1	1
Fibrinogen C-terminal domain-like	TSP-1 type 1 repeat	1	1
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	1	1
Tubby C-terminal domain-like	DNA/RNA polymerases	1	1
Cytochrome b5-like heme/steroid binding domain	Tudor/PWWP/MBT	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Tex N-terminal region-like	SH2 domain	1	1
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
RCC1/BLIP-II	UBA-like	1	1
RING/U-box	Trimerization domain of TRAF	1	1
RNA-binding domain, RBD	Nucleotidyltransferase	1	1
Acetyl-CoA synthetase-like	(Trans)glycosidases	1	1
Composite domain of metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	1	1
RING/U-box	Hairpin loop containing domain-like	1	1
RuvA domain 2-like	DNase I-like	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-binding domain	1	1
RING/U-box	DUSP-like	1	1
Fibronectin type III	MFS general substrate transporter	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	ARM repeat	1	1
Bcl-2 inhibitors of programmed cell death	Invertebrate chitin-binding proteins	1	1
Cobalamin (vitamin B12)-dependent enzymes	Cobalamin (vitamin B12)-dependent enzymes	1	1
TNF receptor-like	TNF receptor-like	1	1
Quinoprotein alcohol dehydrogenase-like	EF-hand	1	1
PYP-like sensor domain (PAS domain)	CheY-like	1	1
vWA-like	Hairpin loop containing domain-like	1	1
vWA-like	SAP domain	1	1
Family A G protein-coupled receptor-like	WD40 repeat-like	1	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	NagB/RpiA/CoA transferase-like	1	1
"Winged helix" DNA-binding domain	occludin/ELL-like	1	1
Nucleotidylyl transferase	Class II aaRS ABD-related	1	1
HlyD-like secretion proteins	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
EF-hand	C-terminal domain of PLC-beta	1	1
P-loop containing nucleoside triphosphate hydrolases	WW domain	1	1
Glutathione synthetase ATP-binding domain-like	NAD(P)-binding Rossmann-fold domains	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	1	1
P-loop containing nucleoside triphosphate hydrolases	MOP-like	1	1
Hairpin loop containing domain-like	Six-hairpin glycosidases	1	1
P-loop containing nucleoside triphosphate hydrolases	Fzo-like conserved region	1	1
UBA-like	WWE domain	1	1
Cupredoxins	HAMP domain-like	1	1
Dihydropteroate synthetase-like	Cobalamin (vitamin B12)-binding domain	1	1
Kelch motif	BAR/IMD domain-like	1	1
Restriction endonuclease-like	EGF/Laminin	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
F-box domain	ApaG-like	1	1
DNA/RNA polymerases	MFS general substrate transporter	1	1
Second domain of FERM	FAT domain of focal adhesion kinase	1	1
Cytochrome c	4Fe-4S ferredoxins	1	1
HAD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
DBL homology domain (DH-domain)	Ras GEF	1	1
TROVE domain-like	vWA-like	1	1
Putative DNA-binding domain	Class II aaRS and biotin synthetases	1	1
Concanavalin A-like lectins/glucanases	PH domain-like	1	1
Carboxypeptidase regulatory domain-like	OmpA-like	1	1
TAFH domain-like	HIT/MYND zinc finger-like	1	1
E set domains	GTPase activation domain, GAP	1	1
I/LWEQ domain	alpha-catenin/vinculin-like	1	1
beta-N-acetylhexosaminidase-like domain	Galactose-binding domain-like	1	1
RCC1/BLIP-II	Tudor/PWWP/MBT	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	S15/NS1 RNA-binding domain	1	1
Transducin (heterotrimeric G protein), gamma chain	Regulator of G-protein signaling, RGS	1	1
Aminoacid dehydrogenase-like, N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Methenyltetrahydrofolate cyclohydrolase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Toll/Interleukin receptor TIR domain	1	1
FMT C-terminal domain-like	ALDH-like	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
L domain-like	ADP-ribosylglycohydrolase	1	1
PH domain-like	RING/U-box	1	1
RING/U-box	SH3-domain	1	1
RING/U-box	Tricorn protease domain 2	1	1
Porins	P-loop containing nucleoside triphosphate hydrolases	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Aspartate/ornithine carbamoyltransferase	1	1
AbfB domain	AbfB domain	1	1
Nucleotidylyl transferase	Alpha-L RNA-binding motif	1	1
DBL homology domain (DH-domain)	SH2 domain	1	1
Concanavalin A-like lectins/glucanases	Fibrinogen C-terminal domain-like	1	1
Bromodomain	Tudor/PWWP/MBT	1	1
Outer arm dynein light chain 1	P-loop containing nucleoside triphosphate hydrolases	1	1
BRCT domain	DBL homology domain (DH-domain)	1	1
Bromodomain	HMG-box	1	1
Class II aaRS and biotin synthetases	Translation proteins	1	1
HAMP domain-like	Homodimeric domain of signal transducing histidine kinase	1	1
Periplasmic binding protein-like I	Nucleotide cyclase	1	1
Carboxypeptidase regulatory domain-like	Carboxypeptidase regulatory domain-like	1	1
Fibronectin type III	SAM/Pointed domain	1	1
Nucleotide cyclase	Metallo-dependent hydrolases	1	1
FnI-like domain	Kringle-like	1	1
P-loop containing nucleoside triphosphate hydrolases	ArfGap/RecO-like zinc finger	1	1
Thioredoxin-like	FabD/lysophospholipase-like	1	1
SH3-domain	PLC-like phosphodiesterases	1	1
HLH, helix-loop-helix DNA-binding domain	HMG-box	1	1
TPR-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Nitric oxide (NO) synthase oxygenase domain	Flavoproteins	1	1
Ubiquitin-like	FYVE/PHD zinc finger	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains	1	1
Chaperone J-domain	ARM repeat	1	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	1	1
alpha/beta-Hydrolases	Carbamate kinase-like	1	1
Pentein	Translation proteins	1	1
p53-like transcription factors	SH2 domain	1	1
Galactose mutarotase-like	Hyaluronate lyase-like, C-terminal domain	1	1
RNI-like	Phospholipase A2, PLA2	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	CalX-like	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
Chaperone J-domain	UBA-like	1	1
Tudor/PWWP/MBT	Cytokine	1	1
Ribonuclease H-like	MFS general substrate transporter	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
PH domain-like	alpha-catenin/vinculin-like	1	1
Multidrug efflux transporter AcrB transmembrane domain	WD40 repeat-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Bet v1-like	1	1
V-type ATP synthase subunit C	Phosphoenolpyruvate/pyruvate domain	1	1
GST C-terminal domain-like	eEF1-gamma domain	1	1
BRCT domain	post-AAA+ oligomerization domain-like	1	1
Phospholipase A2, PLA2	Phospholipase A2, PLA2	1	1
Thioredoxin-like	Nucleoside diphosphate kinase, NDK	1	1
PTPA-like	PTPA-like	1	1
Fibronectin type III	Hect, E3 ligase catalytic domain	1	1
beta-N-acetylhexosaminidase-like domain	EGF/Laminin	1	1
Immunoglobulin	Kringle-like	1	1
E set domains	Cupredoxins	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Ubiquitin-like	Zn-dependent exopeptidases	1	1
STAT	p53-like transcription factors	1	1
Cobalamin (vitamin B12)-binding domain	Methionine synthase activation domain-like	1	1
SH3-domain	beta-beta-alpha zinc fingers	1	1
Protein kinase-like (PK-like)	FAT domain of focal adhesion kinase	1	1
E set domains	Glycosyl hydrolase domain	1	1
SEA domain	TPR-like	1	1
PRTase-like	Ribulose-phoshate binding barrel	1	1
FYVE/PHD zinc finger	RNI-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Precorrin-8X methylmutase CbiC/CobH	1	1
SEA domain	Protein kinase-like (PK-like)	1	1
Ran binding protein zinc finger-like	RING/U-box	1	1
E set domains	Galactose-binding domain-like	1	1
SMAD/FHA domain	Protein kinase-like (PK-like)	1	1
WW domain	PIN domain-like	1	1
Rudiment single hybrid motif	Formyltransferase	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
WD40 repeat-like	Cysteine proteinases	1	1
Calponin-homology domain, CH-domain	SH2 domain	1	1
beta-beta-alpha zinc fingers	Leucine zipper domain	1	1
PRP4-like	WD40 repeat-like	1	1
Nucleotide-binding domain	4Fe-4S ferredoxins	1	1
GroEL apical domain-like	SAICAR synthase-like	1	1
Dihydropteroate synthetase-like	Methionine synthase domain	1	1
EGF/Laminin	Kringle-like	1	1
L domain-like	DNase I-like	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
BEACH domain	FYVE/PHD zinc finger	1	1
Spermadhesin, CUB domain	SEA domain	1	1
Adenine nucleotide alpha hydrolases-like	P-loop containing nucleoside triphosphate hydrolases	1	1
GTPase activation domain, GAP	ARM repeat	1	1
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	1	1
ENT-like	Bromodomain	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
dsRNA-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
WD40 repeat-like	SAM/Pointed domain	1	1
EGF/Laminin	SWIB/MDM2 domain	1	1
F-box domain	DBL homology domain (DH-domain)	1	1
Multidrug efflux transporter AcrB transmembrane domain	DNA breaking-rejoining enzymes	1	1
SH3-domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
NHL repeat	BPTI-like	1	1
C-type lectin-like	Putative cyclase	1	1
vWA-like	Di-copper centre-containing domain	1	1
DBL homology domain (DH-domain)	BAR/IMD domain-like	1	1
Protein kinase-like (PK-like)	HCP-like	1	1
Agglutinin HPA-like	Kazal-type serine protease inhibitors	1	1
EF-hand	Dimeric alpha+beta barrel	1	1
CSL zinc finger	Chaperone J-domain	1	1
Second domain of FERM	SH3-domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	YWTD domain	1	1
Ribonuclease H-like	HRDC-like	1	1
Pentapeptide repeat-like	Nucleoside diphosphate kinase, NDK	1	1
Fibrinogen C-terminal domain-like	Voltage-gated potassium channels	1	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Arp2/3 complex subunits	Arp2/3 complex subunits	1	1
PDZ domain-like	BAR/IMD domain-like	1	1
SRCR-like	Immunoglobulin	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
SH3-domain	Toll/Interleukin receptor TIR domain	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
SH3-domain	WW domain	1	1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	1	1
cAMP-binding domain-like	PDZ domain-like	1	1
XRCC4, N-terminal domain	Immunoglobulin	1	1
PKD domain	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
Ypt/Rab-GAP domain of gyp1p	EGF/Laminin	1	1
EPT/RTPC-like	RNA 3'-terminal phosphate cyclase, RPTC, insert domain	1	1
Adenine nucleotide alpha hydrolases-like	Translation proteins	1	1
TolB, C-terminal domain	TPR-like	1	1
Concanavalin A-like lectins/glucanases	BEACH domain	1	1
MIR domain	ARM repeat	1	1
Phosphofructokinase	Phosphofructokinase	1	1
Terpenoid cyclases/Protein prenyltransferases	TIMP-like	1	1
DNA polymerase beta, N-terminal domain-like	Restriction endonuclease-like	1	1
Kelch motif	Growth factor receptor domain	1	1
MFS general substrate transporter	Ribosomal protein S5 domain 2-like	1	1
SH2 domain	Ras GEF	1	1
PP2C-like	Protein serine/threonine phosphatase 2C, C-terminal domain	1	1
MIT domain	Cysteine proteinases	1	1
RNI-like	Fibronectin type III	1	1
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	1	1
RING/U-box	RNA-binding domain, RBD	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
Cytochrome b5-like heme/steroid binding domain	UBA-like	1	1
p53-like transcription factors	DNA-binding protein LAG-1 (CSL)	1	1
TSP-1 type 1 repeat	C-type lectin-like	1	1
R3H domain	Ankyrin repeat	1	1
Tudor/PWWP/MBT	RING/U-box	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
Tropomyosin	RNI-like	1	1
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
Hypothetical protein c14orf129, hspc210	TPR-like	1	1
HR1 repeat	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
CBS-domain pair	MgtE membrane domain-like	1	1
XRCC4, N-terminal domain	XRCC4, C-terminal oligomerization domain	1	1
MIT domain	MIT domain	1	1
tRNA-binding arm	Class II aaRS and biotin synthetases	1	1
FMN-linked oxidoreductases	4Fe-4S ferredoxins	1	1
Glycosyl hydrolase domain	Glycosyl hydrolase domain	1	1
vWA-like	SPOC domain-like	1	1
Starch-binding domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Dihydropteroate synthetase-like	Methionine synthase activation domain-like	1	1
Ubiquitin-like	GTPase activation domain, GAP	1	1
Cytochrome b5-like heme/steroid binding domain	RING/U-box	1	1
CSL zinc finger	CSL zinc finger	1	1
WD40 repeat-like	Hect, E3 ligase catalytic domain	1	1
Ubiquitin-like	ADP-ribosylation	1	1
Ferritin-like	Ferritin-like	1	1
Outer arm dynein light chain 1	L domain-like	1	1
3-carboxy-cis,cis-mucoante lactonizing enzyme	EGF/Laminin	1	1
SWIB/MDM2 domain	eIF1-like	1	1
alpha/beta-Hydrolases	alpha/beta-Hydrolases	1	1
Chondroitin AC/alginate lyase	Hyaluronate lyase-like, C-terminal domain	1	1
Succinyl-CoA synthetase domains	Citrate synthase	1	1
Galactose-binding domain-like	BRCT domain	1	1
PDZ domain-like	Cysteine-rich domain	1	1
PH domain-like	RCC1/BLIP-II	1	1
Kringle-like	Ricin B-like lectins	1	1
Ricin B-like lectins	Spermadhesin, CUB domain	1	1
PLC-like phosphodiesterases	C-terminal domain of PLC-beta	1	1
vWA-like	PR-1-like	1	1
EGF/Laminin	TIMP-like	1	1
TPR-like	UBA-like	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	1	1
Ras GEF	Cysteine-rich domain	1	1
RCC1/BLIP-II	FYVE/PHD zinc finger	1	1
BPTI-like	Serine protease inhibitors	1	1
Second domain of FERM	Protein kinase-like (PK-like)	1	1
Anthrax protective antigen	Anthrax protective antigen	1	1
Nitric oxide (NO) synthase oxygenase domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
UBA-like	Thioredoxin-like	1	1
HIT/MYND zinc finger-like	HIT/MYND zinc finger-like	1	1
EGF/Laminin	beta-beta-alpha zinc fingers	1	1
Histone-fold	Macro domain-like	1	1
SAP domain	Ribonuclease H-like	1	1
Second domain of FERM	I/LWEQ domain	1	1
Quinoprotein alcohol dehydrogenase-like	Ypt/Rab-GAP domain of gyp1p	1	1
Band 7/SPFH domain	SCP-like	1	1
beta-sandwich domain of Sec23/24	Formin homology 2 domain (FH2 domain)	1	1
Adenine nucleotide alpha hydrolases-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	1	1
Trypsin-like serine proteases	Trypsin-like serine proteases	1	1
Molybdenum cofactor biosynthesis proteins	Adenine nucleotide alpha hydrolases-like	1	1
PurM C-terminal domain-like	Formyltransferase	1	1
EF-hand	Tropomyosin	1	1
TSP-1 type 1 repeat	vWA-like	1	1
L domain-like	UBA-like	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
SAM/Pointed domain	Ubiquitin-like	1	1
RNase III domain-like	RNase III domain-like	1	1
Immunoglobulin	Ribonuclease H-like	1	1
PH domain-like	Wiscott-Aldrich syndrome protein, WASP, C-terminal domain	1	1
TATA-box binding protein-like	TATA-box binding protein-like	1	1
Fibrinogen C-terminal domain-like	Galactose-binding domain-like	1	1
CAD & PB1 domains	Cysteine-rich domain	1	1
RNI-like	Toll/Interleukin receptor TIR domain	1	1
UBA-like	RNI-like	1	1
Ankyrin repeat	SOCS box-like	1	1
PUG domain-like	Cysteine proteinases	1	1
GYF domain	Chaperone J-domain	1	1
Fibrinogen C-terminal domain-like	Fibronectin type III	1	1
Restriction endonuclease-like	DEK C-terminal domain	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain I	1	1
Rhodanese/Cell cycle control phosphatase	WW domain	1	1
XRCC4, C-terminal oligomerization domain	DNase I-like	1	1
EF-hand	Kelch motif	1	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	LysM domain	1	1
ISP domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
Plexin repeat	Plexin repeat	1	1
FYVE/PHD zinc finger	PUA domain-like	1	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	1	1
Tropomyosin	Class II aaRS ABD-related	1	1
dsRNA-binding domain-like	Nudix	1	1
Complement control module/SCR domain	TSP-1 type 1 repeat	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Acyl-CoA binding protein	ClpP/crotonase	1	1
Trimeric LpxA-like enzymes	ARM repeat	1	1
vWA-like	Trypsin-like serine proteases	1	1
Actin-crosslinking proteins	Actin-crosslinking proteins	1	1
RCC1/BLIP-II	Mib/herc2 domain-like	1	1
EGF/Laminin	Tropomyosin	1	1
Ubiquitin-like	Zn-binding ribosomal proteins	1	1
Outer arm dynein light chain 1	Family A G protein-coupled receptor-like	1	1
TSP-1 type 1 repeat	PGBD-like	1	1
SH3-domain	RUN domain-like	1	1
SAP domain	Family A G protein-coupled receptor-like	1	1
MFS general substrate transporter	Periplasmic binding protein-like II	1	1
Immunoglobulin	Invertebrate chitin-binding proteins	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	S15/NS1 RNA-binding domain	1	1
His-Me finger endonucleases	Ribonuclease H-like	1	1
alpha/beta-Hydrolases	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
ARM repeat	PX domain	1	1
Trypsin-like serine proteases	DEATH domain	1	1
RING/U-box	Hect, E3 ligase catalytic domain	1	1
Bacterial hemolysins	RING/U-box	1	1
Tetrahydrobiopterin biosynthesis enzymes-like	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	1	1
S15/NS1 RNA-binding domain	C-terminal domain of ProRS	1	1
L domain-like	NTF2-like	1	1
Formate dehydrogenase/DMSO reductase, domains 1-3	ISP domain	1	1
TPR-like	Fic-like	1	1
EGF/Laminin	Thioesterase/thiol ester dehydrase-isomerase	1	1
NAD(P)-binding Rossmann-fold domains	Citrate synthase	1	1
Class I glutamine amidotransferase-like	Composite domain of metallo-dependent hydrolases	1	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	1	1
Ribosomal protein L25-like	Class II aaRS ABD-related	1	1
EF-hand	FnI-like domain	1	1
GST C-terminal domain-like	C-terminal domain of ProRS	1	1
YccV-like	ApaG-like	1	1
Ubiquitin-like	A middle domain of Talin 1	1	1
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	1	1
Concanavalin A-like lectins/glucanases	Carbohydrate-binding domain	1	1
Eukaryotic type KH-domain (KH-domain type I)	HD-domain/PDEase-like	1	1
Cysteine proteinases	Ribonuclease H-like	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
RNA-binding domain, RBD	GYF domain	1	1
Rudiment single hybrid motif	PurM C-terminal domain-like	1	1
DUSP-like	DUSP-like	1	1
PH domain-like	C-terminal domain of PLC-beta	1	1
Formyltransferase	ALDH-like	1	1
Ras GEF	EF-hand	1	1
ISP domain	FAD/NAD(P)-binding domain	1	1
vWA-like	Sensory domain-like	1	1
Hairpin loop containing domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ribosomal protein L25-like	C-terminal domain of ProRS	1	1
CBS-domain pair	CBS-domain pair	1	1
Ankyrin repeat	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
RCC1/BLIP-II	Cytochrome b5-like heme/steroid binding domain	1	1
MgtE N-terminal domain-like	CBS-domain pair	1	1
FAD/NAD(P)-binding domain	EF-hand	1	1
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	1	1
BRK domain-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Bromodomain	RING/U-box	1	1
Ribosomal protein S5 domain 2-like	Ribulose-phoshate binding barrel	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
EF-hand	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
mRNA decapping enzyme DcpS N-terminal domain	HIT-like	1	1
PHM/PNGase F	NHL repeat	1	1
EAL domain-like	HD-domain/PDEase-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Calponin-homology domain, CH-domain	Thioredoxin-like	1	1
E set domains	EGF/Laminin	1	1
Kazal-type serine protease inhibitors	Thyroglobulin type-1 domain	1	1
SMAD/FHA domain	RING/U-box	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Ankyrin repeat	1	1
SH3-domain	DEATH domain	1	1
DNA/RNA polymerases	DNA breaking-rejoining enzymes	1	1
HAMP domain-like	Nucleotide cyclase	1	1
PDZ domain-like	Regulator of G-protein signaling, RGS	1	1
PAH2 domain	PAH2 domain	1	1
Growth factor receptor domain	Immunoglobulin	1	1
Glucocorticoid receptor-like (DNA-binding domain)	beta-Roll	1	1
RING/U-box	BRCT domain	1	1
V-type ATP synthase subunit C	Thioesterase/thiol ester dehydrase-isomerase	1	1
Ribonuclease H-like	Zinc finger domain of DNA polymerase-alpha	1	1
Homeodomain-like	Cupredoxins	1	1
Ankyrin repeat	WD40 repeat-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Protein kinase-like (PK-like)	1	1
P-loop containing nucleoside triphosphate hydrolases	SH2 domain	1	1
Concanavalin A-like lectins/glucanases	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
CheY-like	Nucleotidyltransferase	1	1
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	1	1
E set domains	Thioredoxin-like	1	1
P-loop containing nucleoside triphosphate hydrolases	AN1-like Zinc finger	1	1
"Winged helix" DNA-binding domain	Regulator of G-protein signaling, RGS	1	1
Metallo-hydrolase/oxidoreductase	Macro domain-like	1	1
BPTI-like	Elafin-like	1	1
vWA-like	Growth factor receptor domain	1	1
Metalloproteases ("zincins"), catalytic domain	C-type lectin-like	1	1
NAP-like	Ankyrin repeat	1	1
PRTase-like	PRTase-like	1	1
DNA/RNA polymerases	DHH phosphoesterases	1	1
CAD & PB1 domains	His-Me finger endonucleases	1	1
Fibronectin type III	Family A G protein-coupled receptor-like	1	1
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
POZ domain	Galactose-binding domain-like	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
SMI1/KNR4-like	ApaG-like	1	1
post-AAA+ oligomerization domain-like	post-AAA+ oligomerization domain-like	1	1
Isocitrate/Isopropylmalate dehydrogenase-like	Porins	1	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	1	1
Thioesterase/thiol ester dehydrase-isomerase	Bet v1-like	1	1
"Winged helix" DNA-binding domain	TSP-1 type 1 repeat	1	1
SH2 domain	Ankyrin repeat	1	1
Second domain of FERM	Ras GEF	1	1
Calponin-homology domain, CH-domain	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	1	1
Intermediate filament protein, coiled coil region	Lamin A/C globular tail domain	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
FF domain	FF domain	1	1
PH domain-like	RNI-like	1	1
E set domains	AMPKBI-like	1	1
SH2 domain	SH2 domain	1	1
EGF/Laminin	V-type ATP synthase subunit C	1	1
alpha/beta-Hydrolases	Oligoxyloglucan reducing end-specific cellobiohydrolase	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Protein kinase-like (PK-like)	PDZ domain-like	1	1
Fibronectin type III	(Phosphotyrosine protein) phosphatases II	1	1
EGF/Laminin	Ankyrin repeat	1	1
GST C-terminal domain-like	Class II aaRS ABD-related	1	1
UBA-like	XPC-binding domain	1	1
PUA domain-like	Nucleotidylyl transferase	1	1
ARID-like	FYVE/PHD zinc finger	1	1
Homocysteine S-methyltransferase	Dihydropteroate synthetase-like	1	1
lambda repressor-like DNA-binding domains	TNF-like	1	1
DNase I-like	RNA-binding domain, RBD	1	1
Immunoglobulin	(Phosphotyrosine protein) phosphatases II	1	1
ACT-like	6-phosphogluconate dehydrogenase C-terminal domain-like	1	1
EGF/Laminin	Notch domain	1	1
FKBP-like	FKBP-like	1	1
MAST3 pre-PK domain-like	Protein kinase-like (PK-like)	1	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	1	1
Histone-fold	ARM repeat	1	1
CalX-like	(Phosphotyrosine protein) phosphatases II	1	1
Actin-like ATPase domain	NAD kinase/diacylglycerol kinase-like	1	1
Ribonuclease H-like	EGF/Laminin	1	1
DEATH domain	NHL repeat	1	1
Family A G protein-coupled receptor-like	Spectrin repeat	1	1
Nitric oxide (NO) synthase oxygenase domain	Riboflavin synthase domain-like	1	1
EF-hand	DUSP-like	1	1
ARM repeat	Zn-dependent exopeptidases	1	1
L domain-like	PDZ domain-like	1	1
TSP-1 type 1 repeat	Periplasmic binding protein-like II	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
RNI-like	Galactose-binding domain-like	1	1
Spectrin repeat	GAS2 domain-like	1	1
TNF-like	TNF-like	1	1
Urease, beta-subunit	Metallo-dependent hydrolases	1	1
PH domain-like	NAD kinase/diacylglycerol kinase-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Chaperone J-domain	1	1
CheW-like	CheY-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Clavaminate synthase-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ribulose-phoshate binding barrel	all-alpha NTP pyrophosphatases	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ATP-dependent DNA ligase DNA-binding domain	1	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	1	1
WD40 repeat-like	MFS general substrate transporter	1	1
F-box domain	Cyclin-like	1	1
Nucleotide-diphospho-sugar transferases	Poly A polymerase C-terminal region-like	1	1
TPR-like	Tropomyosin	1	1
EGF/Laminin	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
SMAD/FHA domain	PH domain-like	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
DNA-glycosylase	Nudix	1	1
Thioredoxin-like	Galactose-binding domain-like	1	1
TAFH domain-like	Histone-fold	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Alpha-L RNA-binding motif	Pseudouridine synthase	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
Retrovirus zinc finger-like domains	Nucleotidyltransferase	1	1
BRCT domain	DNA/RNA polymerases	1	1
Pentapeptide repeat-like	Concanavalin A-like lectins/glucanases	1	1
Kazal-type serine protease inhibitors	Concanavalin A-like lectins/glucanases	1	1
L domain-like	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Myosin S1 fragment, N-terminal domain	Myosin rod fragments	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Calcium-dependent phosphotriesterase	YWTD domain	1	1
Epsilon subunit of F1F0-ATP synthase N-terminal domain	Epsilon subunit of F1F0-ATP synthase C-terminal domain	1	1
Intermediate filament protein, coiled coil region	Intermediate filament protein, coiled coil region	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
Ubiquitin-like	FAD-binding/transporter-associated domain-like	1	1
MIT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
L domain-like	Actin depolymerizing proteins	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
Sema domain	GTPase activation domain, GAP	1	1
OmpA-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
(Trans)glycosidases	Invertebrate chitin-binding proteins	1	1
PH domain-like	A middle domain of Talin 1	1	1
Hairpin loop containing domain-like	Kringle-like	1	1
R3H domain	RNA-binding domain, RBD	1	1
TIMP-like	TIMP-like	1	1
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains	1	1
FYVE/PHD zinc finger	GroEL apical domain-like	1	1
Phage fibre proteins	(Phosphotyrosine protein) phosphatases II	1	1
Cupredoxins	Pectin lyase-like	1	1
Galactose-binding domain-like	Hyaluronate lyase-like, C-terminal domain	1	1
Ferredoxin reductase-like, C-terminal NADP-linked domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
NAD kinase/diacylglycerol kinase-like	Ankyrin repeat	1	1
Ribonuclease H-like	SH2 domain	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Galactose oxidase, central domain	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
CHY zinc finger-like	CHY zinc finger-like	1	1
IP3 receptor type 1 binding core, domain 2	IP3 receptor type 1 binding core, domain 2	1	1
Class I glutamine amidotransferase-like	Methylglyoxal synthase-like	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	1	1
Nucleotidylyl transferase	Class II aaRS and biotin synthetases	1	1
PX domain	GTPase activation domain, GAP	1	1
TSP-1 type 1 repeat	SEA domain	1	1
SIS domain	SIS domain	1	1
UBA-like	Tudor/PWWP/MBT	1	1
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	1	1
HCP-like	Cyclin-like	1	1
PH domain-like	Ran binding protein zinc finger-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Nucleotide-binding domain	1	1
POZ domain	Skp1 dimerisation domain-like	1	1
Thioredoxin-like	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	1	1
NTF2-like	Fibrinogen C-terminal domain-like	1	1
Tudor/PWWP/MBT	BRCT domain	1	1
PreATP-grasp domain	Aspartate/ornithine carbamoyltransferase	1	1
Tudor/PWWP/MBT	CCHHC domain	1	1
Glycerol-3-phosphate (1)-acyltransferase	Glycerol-3-phosphate (1)-acyltransferase	1	1
Fibronectin type III	Periplasmic binding protein-like II	1	1
GST C-terminal domain-like	Class II aaRS and biotin synthetases	1	1
Fibrinogen C-terminal domain-like	SNARE-like	1	1
ACT-like	Aromatic aminoacid monoxygenases, catalytic and oligomerization domains	1	1
ARM repeat	BEACH domain	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
Porins	Homeodomain-like	1	1
RING/U-box	ADP-ribosylglycohydrolase	1	1
Tudor/PWWP/MBT	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	1	1
PreATP-grasp domain	PurM C-terminal domain-like	1	1
BSD domain-like	BSD domain-like	1	1
SMAD/FHA domain	BRCT domain	1	1
Surp module (SWAP domain)	Surp module (SWAP domain)	1	1
SRCR-like	Spermadhesin, CUB domain	1	1
L domain-like	Hormone receptor domain	1	1
Isocitrate/Isopropylmalate dehydrogenase-like	HlyD-like secretion proteins	1	1
beta-beta-alpha zinc fingers	RNA-binding domain, RBD	1	1
ARM repeat	Fibronectin type III	1	1
Lipoxigenase	beta-beta-alpha zinc fingers	1	1
ParB/Sulfiredoxin	KorB DNA-binding domain-like	1	1
EGF/Laminin	Invertebrate chitin-binding proteins	1	1
Domain of poly(ADP-ribose) polymerase	vWA-like	1	1
Thiolase-like	SCP-like	1	1
RING/U-box	Cyclophilin-like	1	1
Lamin A/C globular tail domain	WD40 repeat-like	1	1
PDZ domain-like	PX domain	1	1
Protein kinase-like (PK-like)	L27 domain	1	1
CRAL/TRIO domain	(Phosphotyrosine protein) phosphatases II	1	1
PH domain-like	Phospholipase D/nuclease	1	1
RCC1/BLIP-II	PABC (PABP) domain	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
RING/U-box	Galactose-binding domain-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Hect, E3 ligase catalytic domain	1	1
Sema domain	E set domains	1	1
Nucleotide-diphospho-sugar transferases	Ribosomal protein S5 domain 2-like	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
beta-beta-alpha zinc fingers	PAP/OAS1 substrate-binding domain	1	1
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	1	1
Galactose-binding domain-like	Voltage-gated potassium channels	1	1
UBA-like	Galactose-binding domain-like	1	1
(Trans)glycosidases	Acyl-CoA N-acyltransferases (Nat)	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
EGF/Laminin	Lipoxigenase	1	1
GAT-like domain	Clathrin adaptor appendage domain	1	1
RuvA domain 2-like	F-box domain	1	1
HIT-like	HIT-like	1	1
Ankyrin repeat	Hect, E3 ligase catalytic domain	1	1
Ankyrin repeat	L domain-like	1	1
TSP-1 type 1 repeat	Anthrax protective antigen	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
Galactose-binding domain-like	SAM/Pointed domain	1	1
Metallo-dependent phosphatases	5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain	1	1
FnI-like domain	Serine protease inhibitors	1	1
Clathrin heavy-chain terminal domain	ARM repeat	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
Cysteine proteinases	Galactose-binding domain-like	1	1
Spectrin repeat	WW domain	1	1
G protein-binding domain	Cysteine-rich domain	1	1
TRAF domain-like	Trimerization domain of TRAF	1	1
Ubiquitin-like	FAT domain of focal adhesion kinase	1	1
Thioredoxin-like	AraD/HMP-PK domain-like	1	1
SAP domain	SAP domain	1	1
(Phosphotyrosine protein) phosphatases II	FYVE/PHD zinc finger	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
EPT/RTPC-like	EPT/RTPC-like	1	1
Clavaminate synthase-like	Tudor/PWWP/MBT	1	1
Inhibitor of apoptosis (IAP) repeat	Inhibitor of apoptosis (IAP) repeat	1	1
TSP-1 type 1 repeat	PR-1-like	1	1
PR-1-like	WD40 repeat-like	1	1
F-box domain	PH domain-like	1	1
Thioredoxin-like	FAD/NAD(P)-binding domain	1	1
RNA-binding domain, RBD	F-box domain	1	1
"Winged helix" DNA-binding domain	Ras GEF	1	1
Tudor/PWWP/MBT	EGF/Laminin	1	1
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Pyrimidine nucleoside phosphorylase C-terminal domain	1	1
Pre-PUA domain	PUA domain-like	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Family A G protein-coupled receptor-like	1	1
Ubiquitin-like	Acid proteases	1	1
F-box domain	Fibronectin type III	1	1
Tudor/PWWP/MBT	Galactose-binding domain-like	1	1
L domain-like	EGF/Laminin	1	1
Cap-Gly domain	Protein kinase-like (PK-like)	1	1
Concanavalin A-like lectins/glucanases	SOCS box-like	1	1
Plexin repeat	E set domains	1	1
DUSP-like	Ubiquitin-like	1	1
CRAL/TRIO N-terminal domain	PapD-like	1	1
E set domains	Terpenoid cyclases/Protein prenyltransferases	1	1
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	1	1
B-box zinc-binding domain	TRAF domain-like	1	1
CRAL/TRIO N-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
SMAD/FHA domain	PDZ domain-like	1	1
Nucleotide-diphospho-sugar transferases	GHMP Kinase, C-terminal domain	1	1
Second domain of FERM	A middle domain of Talin 1	1	1
C-type lectin-like	vWA-like	1	1
E set domains	Transglutaminase, two C-terminal domains	1	1
CheY-like	Methylesterase CheB, C-terminal domain	1	1
PLP-dependent transferases	Rudiment single hybrid motif	1	1
NAD kinase/diacylglycerol kinase-like	CheY-like	1	1
RNA-binding domain, RBD	RNI-like	1	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	1	1
TPR-like	CBS-domain pair	1	1
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	1	1
GTPase activation domain, GAP	Bet v1-like	1	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	1	1
Quinoprotein alcohol dehydrogenase-like	YVTN repeat-like/Quinoprotein amine dehydrogenase	1	1
PYP-like sensor domain (PAS domain)	HD-domain/PDEase-like	1	1
MgtE N-terminal domain-like	MgtE membrane domain-like	1	1
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	1	1
L domain-like	WD40 repeat-like	1	1
Notch domain	Notch domain	1	1
WD40 repeat-like	Chromo domain-like	1	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	1	1
Rudiment single hybrid motif	PurM N-terminal domain-like	1	1
SH3-domain	ARM repeat	1	1
S13-like H2TH domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Ubiquitin-like	Cap-Gly domain	1	1
PA domain	RING/U-box	1	1
Thioredoxin-like	FAD-dependent thiol oxidase	1	1
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	1	1
Regulator of G-protein signaling, RGS	Ubiquitin-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	VPS9 domain	1	1
R3H domain	AN1-like Zinc finger	1	1
CCHHC domain	CCHHC domain	1	1
WD40 repeat-like	Tricorn protease domain 2	1	1
Growth factor receptor domain	Protein kinase-like (PK-like)	1	1
RuvA domain 2-like	SH2 domain	1	1
TAZ domain	Kix domain of CBP (creb binding protein)	1	1
DNA/RNA polymerases	Zinc finger domain of DNA polymerase-alpha	1	1
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	1	1
PHM/PNGase F	BPTI-like	1	1
FYVE/PHD zinc finger	SAP domain	1	1
Transmembrane di-heme cytochromes	Radical SAM enzymes	1	1
SAICAR synthase-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
P-loop containing nucleoside triphosphate hydrolases	PLC-like phosphodiesterases	1	1
Periplasmic binding protein-like II	Nucleotide cyclase	1	1
PH domain-like	Bet v1-like	1	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
Ypt/Rab-GAP domain of gyp1p	SH3-domain	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Sialidases	UDP-Glycosyltransferase/glycogen phosphorylase	1	1
Cysteine proteinases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
ARM repeat	Mib/herc2 domain-like	1	1
L9 N-domain-like	Ribonuclease H-like	1	1
Glutathione synthetase ATP-binding domain-like	Aspartate/ornithine carbamoyltransferase	1	1
DNA breaking-rejoining enzymes	Nucleic acid-binding proteins	1	1
LDL receptor-like module	Lipovitellin-phosvitin complex; beta-sheet shell regions	1	1
ENTH/VHS domain	FYVE/PHD zinc finger	1	1
NAD(P)-binding Rossmann-fold domains	ACT-like	1	1
PABC (PABP) domain	Hect, E3 ligase catalytic domain	1	1
Immunoglobulin	Thyroglobulin type-1 domain	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
HD-domain/PDEase-like	HD-domain/PDEase-like	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	Precorrin-8X methylmutase CbiC/CobH	1	1
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain	WD40 repeat-like	1	1
Plexin repeat	GTPase activation domain, GAP	1	1
NAD(P)-binding Rossmann-fold domains	RING/U-box	1	1
WW domain	FKBP-like	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
Chaperone J-domain	Sec63 N-terminal domain-like	1	1
CAD & PB1 domains	Six-hairpin glycosidases	1	1
Periplasmic binding protein-like II	Protein kinase-like (PK-like)	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
PreATP-grasp domain	Formyltransferase	1	1
Ribosomal protein S5 domain 2-like	Periplasmic binding protein-like II	1	1
Class I glutamine amidotransferase-like	Metallo-dependent hydrolases	1	1
CBS-domain pair	Nucleotide-diphospho-sugar transferases	1	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
Ubiquitin-like	TPR-like	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
NAD(P)-binding Rossmann-fold domains	Thioesterase/thiol ester dehydrase-isomerase	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Ribokinase-like	1	1
SET domain	beta-lactamase/transpeptidase-like	1	1
TAZ domain	Bromodomain	1	1
BAR/IMD domain-like	Ankyrin repeat	1	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	1	1
Porins	CarD-like	1	1
SEA domain	RING/U-box	1	1
HR1 repeat	PDZ domain-like	1	1
Phase 1 flagellin	Phase 1 flagellin	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Cysteine proteinases	Ankyrin repeat	1	1
DNase I-like	GTPase activation domain, GAP	1	1
TPR-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
PYP-like sensor domain (PAS domain)	Nucleotide cyclase	1	1
P-loop containing nucleoside triphosphate hydrolases	Alkaline phosphatase-like	1	1
Cyclophilin-like	TPR-like	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
UBC-like	Ribosomal protein S5 domain 2-like	1	1
ISP domain	Bet v1-like	1	1
EF-hand	Eferin C-derminal domain-like	1	1
"Winged helix" DNA-binding domain	PLP-dependent transferases	1	1
Serine protease inhibitors	Serine protease inhibitors	1	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	1	1
P-loop containing nucleoside triphosphate hydrolases	Chaperone J-domain	1	1
Cysteine proteinases	Globin-like	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
alpha/beta knot	Nucleic acid-binding proteins	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
Ubiquitin-like	SMAD/FHA domain	1	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	1	1
EAL domain-like	Metallo-dependent hydrolases	1	1
SH2 domain	PLC-like phosphodiesterases	1	1
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	1	1
WD40 repeat-like	Putative isomerase YbhE	1	1
ARM repeat	Family A G protein-coupled receptor-like	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	1	1
Transglutaminase, two C-terminal domains	Transglutaminase, two C-terminal domains	1	1
POZ domain	WD40 repeat-like	1	1
Growth factor receptor domain	Notch domain	1	1
GMP synthetase C-terminal dimerisation domain	GMP synthetase C-terminal dimerisation domain	1	1
ARM repeat	WWE domain	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	Fibronectin type III	1	1
Rhomboid-like	UBA-like	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
L27 domain	L27 domain	1	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	1	1
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	1	1
TRAF domain-like	Cysteine proteinases	1	1
Ribonuclease H-like	Fibronectin type III	1	1
Ubiquitin-like	XPC-binding domain	1	1
CAD & PB1 domains	PDZ domain-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	MetI-like	1	1
Ankyrin repeat	FabD/lysophospholipase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
Tricorn protease domain 2	ARM repeat	1	1
Ankyrin repeat	FYVE/PHD zinc finger	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
ARM repeat	CalX-like	1	1
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
HAD-like	alpha/beta-Hydrolases	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	1	1
EF-hand	GAF domain-like	1	1
Calcium-dependent phosphotriesterase	EGF/Laminin	1	1
Alkaline phosphatase-like	His-Me finger endonucleases	1	1
"Winged helix" DNA-binding domain	Dimeric alpha+beta barrel	1	1
PLP-dependent transferases	PLP-dependent transferases	1	1
WD40 repeat-like	E set domains	1	1
CBS-domain pair	cAMP-binding domain-like	1	1
PurS-like	PurM C-terminal domain-like	1	1
PLP-dependent transferases	Adenine nucleotide alpha hydrolases-like	1	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	Nucleotide-binding domain	1	1
Hairpin loop containing domain-like	DNA/RNA polymerases	1	1
ACP-like	Trimeric LpxA-like enzymes	1	1
Chaperone J-domain	E set domains	1	1
Ribonuclease H-like	RNA-binding domain, RBD	1	1
F-box domain	Fibrinogen C-terminal domain-like	1	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	1	1
Protein kinase-like (PK-like)	Toll/Interleukin receptor TIR domain	1	1
Hypothetical protein c14orf129, hspc210	ARM repeat	1	1
EGF/Laminin	Phosphoenolpyruvate/pyruvate domain	1	1
Cysteine proteinases	Transglutaminase, two C-terminal domains	1	1
Fibronectin type III	Complement control module/SCR domain	1	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	1	1
TAZ domain	RING/U-box	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
Ankyrin repeat	Cap-Gly domain	1	1
HSP20-like chaperones	Riboflavin synthase domain-like	1	1
vWA-like	SRCR-like	1	1
A middle domain of Talin 1	I/LWEQ domain	1	1
TPR-like	RNA-binding domain, RBD	1	1
ArfGap/RecO-like zinc finger	SH3-domain	1	1
Macro domain-like	CRAL/TRIO domain	1	1
Ypt/Rab-GAP domain of gyp1p	Concanavalin A-like lectins/glucanases	1	1
ACT-like	ACT-like	1	1
Apolipoprotein A-I	NHL repeat	1	1
HR1 repeat	HR1 repeat	1	1
Growth factor receptor domain	Ankyrin repeat	1	1
HR1 repeat	Protein kinase-like (PK-like)	1	1
F-box domain	Kelch motif	1	1
MFS general substrate transporter	PH domain-like	1	1
C-type lectin-like	ARM repeat	1	1
Ubiquitin-like	(Phosphotyrosine protein) phosphatases II	1	1
Dcp2 domain-like	Nudix	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Fibronectin type III	1	1
Bet v1-like	HAD-like	1	1
TAZ domain	TAZ domain	1	1
TRAF domain-like	NRDP1 C-terminal domain-like	1	1
Translation proteins SH3-like domain	Translation proteins SH3-like domain	1	1
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	1	1
DEK C-terminal domain	(Phosphotyrosine protein) phosphatases II	1	1
Tudor/PWWP/MBT	Fibrinogen C-terminal domain-like	1	1
SNF-like	Bet v1-like	1	1
alpha-helical ferredoxin	4Fe-4S ferredoxins	1	1
PheT/TilS domain	Class II aaRS and biotin synthetases	1	1
Actin-like ATPase domain	CheW-like	1	1
Second domain of FERM	DBL homology domain (DH-domain)	1	1
P-loop containing nucleoside triphosphate hydrolases	Phospholipase A2, PLA2	1	1
Glutathione synthetase ATP-binding domain-like	PurM N-terminal domain-like	1	1
Actin depolymerizing proteins	SH3-domain	1	1
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	1	1
EF-hand	NAD kinase/diacylglycerol kinase-like	1	1
MurCD N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
RING/U-box	Fibrinogen C-terminal domain-like	1	1
Putative DNA-binding domain	PheT/TilS domain	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Composite domain of metallo-dependent hydrolases	1	1
Retrovirus zinc finger-like domains	DNase I-like	1	1
SEA domain	Family A G protein-coupled receptor-like	1	1
Plexin repeat	TSP-1 type 1 repeat	1	1
(Trans)glycosidases	Six-hairpin glycosidases	1	1
SH2 domain	Cysteine-rich domain	1	1
Putative DNA-binding domain	Putative DNA-binding domain	1	1
Clavaminate synthase-like	Tetraspanin	1	1
ISP transmembrane anchor	ISP domain	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Galactose-binding domain-like	Family A G protein-coupled receptor-like	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
GAF domain-like	PYP-like sensor domain (PAS domain)	1	1
Cytochrome P450	Cytochrome P450	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
SMAD/FHA domain	dsRNA-binding domain-like	1	1
Kringle-like	Concanavalin A-like lectins/glucanases	1	1
PR-1-like	SOCS box-like	1	1
Calponin-homology domain, CH-domain	DNA/RNA polymerases	1	1
Spermadhesin, CUB domain	Trypsin-like serine proteases	1	1
Phage tail proteins	gp5 N-terminal domain-like	1	1
Tubby C-terminal domain-like	His-Me finger endonucleases	1	1
L domain-like	Fibronectin type III	1	1
P-loop containing nucleoside triphosphate hydrolases	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Chaperone J-domain	EPT/RTPC-like	1	1
Multiheme cytochromes	Family A G protein-coupled receptor-like	1	1
RING/U-box	NRDP1 C-terminal domain-like	1	1
POZ domain	Pentapeptide repeat-like	1	1
Calpain large subunit, middle domain (domain III)	Calpain large subunit, middle domain (domain III)	1	1
UBA-like	Peptidyl-tRNA hydrolase II	1	1
P-loop containing nucleoside triphosphate hydrolases	GTPase activation domain, GAP	1	1
Ricin B-like lectins	Alkaline phosphatase-like	1	1
Homeodomain-like	TNF-like	1	1
ARM repeat	EF-hand	1	1
Glycerol-3-phosphate (1)-acyltransferase	Cysteine proteinases	1	1
EF-hand	PX domain	1	1
BRCT domain	ADP-ribosylation	1	1
PH domain-like	I/LWEQ domain	1	1
vWA-like	Immunoglobulin	1	1
Anthrax protective antigen	Voltage-gated potassium channels	1	1
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	1	1
Homocysteine S-methyltransferase	Methionine synthase domain	1	1
SAP domain	Cytochrome b5-like heme/steroid binding domain	1	1
DNase I-like	C-type lectin-like	1	1
RNA-binding domain, RBD	PAP/OAS1 substrate-binding domain	1	1
PH domain-like	FAT domain of focal adhesion kinase	1	1
PDZ domain-like	(Phosphotyrosine protein) phosphatases II	1	1
Ribosomal protein L25-like	Class II aaRS and biotin synthetases	1	1
Immunoglobulin	MFS general substrate transporter	1	1
Nucleotidylyl transferase	MOP-like	1	1
DNA breaking-rejoining enzymes	Eukaryotic DNA topoisomerase I, dispensable insert domain	1	1
Homeodomain-like	Nucleotide cyclase	1	1
Nucleotide cyclase	Composite domain of metallo-dependent hydrolases	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
Hormone receptor domain	Family A G protein-coupled receptor-like	1	1
SMAD/FHA domain	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Mib/herc2 domain-like	Mib/herc2 domain-like	1	1
Immunoglobulin	Hormone receptor domain	1	1
Subtilisin-like	Subtilisin-like	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	UBA-like	1	1
Metallo-dependent phosphatases	EF-hand	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	1	1
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	1	1
Zn-dependent exopeptidases	Zn-dependent exopeptidases	1	1
SH3-domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	1	1
ENTH/VHS domain	Clathrin adaptor appendage domain	1	1
Histone-fold	POZ domain	1	1
Urease, gamma-subunit	Urease, beta-subunit	1	1
Kazal-type serine protease inhibitors	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
RING/U-box	WWE domain	1	1
TPR-like	OmpA-like	1	1
FYVE/PHD zinc finger	EF-hand	1	1
Ribonuclease H-like	CCCH zinc finger	1	1
Growth factor receptor domain	TNF receptor-like	1	1
beta-beta-alpha zinc fingers	WW domain	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	PKD domain	1	1
DBL homology domain (DH-domain)	DBL homology domain (DH-domain)	1	1
RNI-like	Fibrinogen C-terminal domain-like	1	1
Class I glutamine amidotransferase-like	Aspartate/ornithine carbamoyltransferase	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Periplasmic binding protein-like I	Voltage-gated potassium channels	1	1
Homeodomain-like	SIS domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Quinoprotein alcohol dehydrogenase-like	1	1
Adhesin YadA, collagen-binding domain	Pseudouridine synthase	1	1
UBA-like	Ricin B-like lectins	1	1
Second domain of FERM	alpha-catenin/vinculin-like	1	1
p53-like transcription factors	p53 tetramerization domain	1	1
E set domains	Hect, E3 ligase catalytic domain	1	1
PGBD-like	L,D-transpeptidase catalytic domain-like	1	1
Calpain large subunit, middle domain (domain III)	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Putative DNA-binding domain	SAND domain-like	1	1
Flavoproteins	Radical SAM enzymes	1	1
Ubiquitin-like	I/LWEQ domain	1	1
Rap/Ran-GAP	Rap/Ran-GAP	1	1
Cytochrome b5-like heme/steroid binding domain	Galactose-binding domain-like	1	1
Metalloproteases ("zincins"), catalytic domain	Complement control module/SCR domain	1	1
Ribosomal protein L6	Ribosomal protein L6	1	1
Indigoidine synthase A-like	Ribokinase-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	Pentein	1	1
Calponin-homology domain, CH-domain	Ankyrin repeat	1	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	1	1
Microbial and mitochondrial ADK, insert "zinc finger" domain	Microbial and mitochondrial ADK, insert "zinc finger" domain	1	1
L domain-like	SAM/Pointed domain	1	1
NAD kinase/diacylglycerol kinase-like	CheW-like	1	1
PLC-like phosphodiesterases	C-type lectin-like	1	1
SRCR-like	Trypsin-like serine proteases	1	1
Ribulose-phoshate binding barrel	Periplasmic binding protein-like II	1	1
DEATH domain	SH2 domain	1	1
AF0104/ALDC/Ptd012-like	AF0104/ALDC/Ptd012-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
WD40 repeat-like	SNARE fusion complex	1	1
Retrovirus zinc finger-like domains	Acid proteases	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	C-terminal domain of PLC-beta	1	1
Immunoglobulin	Fibrinogen C-terminal domain-like	1	1
PUG domain-like	RING/U-box	1	1
TPR-like	MgtE N-terminal domain-like	1	1
Spectrin repeat	RING/U-box	1	1
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	1	1
WD40 repeat-like	Bromodomain	1	1
FYVE/PHD zinc finger	SAICAR synthase-like	1	1
Seven-hairpin glycosidases	Seven-hairpin glycosidases	1	1
Ankyrin repeat	Second domain of FERM	1	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	1	1
ARM repeat	Second domain of FERM	1	1
PDZ domain-like	EF-hand	1	1
RCC1/BLIP-II	Galactose-binding domain-like	1	1
Acyl-CoA binding protein	Ankyrin repeat	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
TPR-like	PIN domain-like	1	1
Glutathione synthetase ATP-binding domain-like	PurM C-terminal domain-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
RCC1/BLIP-II	RING/U-box	1	1
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	1	1
PUG domain-like	Ran binding protein zinc finger-like	1	1
L9 N-domain-like	Ribosomal protein L9 C-domain	1	1
EF-hand	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
RmlC-like cupins	RmlC-like cupins	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Calponin-homology domain, CH-domain	Glucocorticoid receptor-like (DNA-binding domain)	1	1
RING/U-box	R3H domain	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
Porins	Porins	1	1
ARM repeat	Galactose-binding domain-like	1	1
Mib/herc2 domain-like	UBA-like	1	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	1	1
GST C-terminal domain-like	S15/NS1 RNA-binding domain	1	1
Class II aaRS ABD-related	C-terminal domain of ProRS	1	1
Tubby C-terminal domain-like	Ribonuclease H-like	1	1
Concanavalin A-like lectins/glucanases	FYVE/PHD zinc finger	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
HAD-like	Acyl-CoA dehydrogenase NM domain-like	1	1
EGF/Laminin	TSP type-3 repeat	1	1
Glutathione synthetase ATP-binding domain-like	Formyltransferase	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
RNI-like	Voltage-gated potassium channels	1	1
RNA-binding domain, RBD	SPOC domain-like	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Aspartate/ornithine carbamoyltransferase	1	1
Cytochrome c oxidase subunit I-like	Cytochrome c	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
TSP-1 type 1 repeat	Cadherin-like	1	1
Concanavalin A-like lectins/glucanases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	1	1
Ypt/Rab-GAP domain of gyp1p	EF-hand	1	1
Thioredoxin-like	Family A G protein-coupled receptor-like	1	1
STAT	SH2 domain	1	1
TRAF domain-like	TPR-like	1	1
Concanavalin A-like lectins/glucanases	ADP-ribosylation	1	1
Ankyrin repeat	FAD-binding/transporter-associated domain-like	1	1
TIMP-like	Concanavalin A-like lectins/glucanases	1	1
CCHHC domain	Acyl-CoA N-acyltransferases (Nat)	1	1
C-type lectin-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
PDZ domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
DEK C-terminal domain	SWIB/MDM2 domain	1	1
Nucleotidylyl transferase	Nucleotidylyl transferase	1	1
Ricin B-like lectins	Immunoglobulin	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
dsRNA-binding domain-like	R3H domain	1	1
Ubiquitin-like	SH3-domain	1	1
Protein kinase-like (PK-like)	Ypt/Rab-GAP domain of gyp1p	1	1
P-loop containing nucleoside triphosphate hydrolases	Ran binding protein zinc finger-like	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
Sensory domain-like	PR-1-like	1	1
Protein kinase-like (PK-like)	Rhodanese/Cell cycle control phosphatase	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
Homocysteine S-methyltransferase	Cobalamin (vitamin B12)-binding domain	1	1
USP8 N-terminal domain-like	WW domain	1	1
RUN domain-like	Lipase/lipooxygenase domain (PLAT/LH2 domain)	1	1
BRK domain-like	Bromodomain	1	1
EAL domain-like	Composite domain of metallo-dependent hydrolases	1	1
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	1	1
vWA-like	FYVE/PHD zinc finger	1	1
Galactose-binding domain-like	Kelch motif	1	1
DBL homology domain (DH-domain)	FYVE/PHD zinc finger	1	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
Immunoglobulin	Frizzled cysteine-rich domain	1	1
E set domains	cAMP-binding domain-like	1	1
(Trans)glycosidases	Restriction endonuclease-like	1	1
"Winged helix" DNA-binding domain	Transducin (heterotrimeric G protein), gamma chain	1	1
Doublecortin (DC)	Protein kinase-like (PK-like)	1	1
Nucleotide-diphospho-sugar transferases	Nucleotidyltransferase	1	1
Mib/herc2 domain-like	Tudor/PWWP/MBT	1	1
IP3 receptor type 1 binding core, domain 2	ARM repeat	1	1
Lipovitellin-phosvitin complex; beta-sheet shell regions	Lipovitellin-phosvitin complex; beta-sheet shell regions	1	1
WD40 repeat-like	TolB, C-terminal domain	1	1
FMN-linked oxidoreductases	Galactose-binding domain-like	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Ricin B-like lectins	Galactose-binding domain-like	1	1
Amidase signature (AS) enzymes	Cytokine	1	1
"Winged helix" DNA-binding domain	GroEL apical domain-like	1	1
Spermadhesin, CUB domain	Complement control module/SCR domain	1	1
Ribosomal protein L25-like	S15/NS1 RNA-binding domain	1	1
TSP-1 type 1 repeat	Spermadhesin, CUB domain	1	1
RAP domain-like	RAP domain-like	1	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PEBP-like	1	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Voltage-gated potassium channels	1	1
FAD-linked reductases, C-terminal domain	EF-hand	1	1
cAMP-binding domain-like	FabD/lysophospholipase-like	1	1
SAP domain	RING/U-box	1	1
Cytochrome b5-like heme/steroid binding domain	Mib/herc2 domain-like	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Periplasmic binding protein-like II	1	1
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	1	1
F-box domain	RING/U-box	1	1
Kazal-type serine protease inhibitors	FnI-like domain	1	1
PDZ domain-like	Concanavalin A-like lectins/glucanases	1	1
beta-beta-alpha zinc fingers	Nucleotidyltransferase	1	1
A heparin-binding domain	CAPPD, an extracellular domain of amyloid beta A4 protein	1	1
PUG domain-like	Galactose-binding domain-like	1	1
DNase I-like	EGF/Laminin	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
PH domain-like	Regulator of G-protein signaling, RGS	1	1
(Phosphotyrosine protein) phosphatases II	Cysteine-rich domain	1	1
Concanavalin A-like lectins/glucanases	Serine protease inhibitors	1	1
PH domain-like	Cullin repeat-like	1	1
Ankyrin repeat	EF-hand	1	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	1	1
Doublecortin (DC)	Ricin B-like lectins	1	1
Histone-fold	DBL homology domain (DH-domain)	1	1
WW domain	RING/U-box	1	1
THUMP domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Saposin	SGNH hydrolase	1	1
HAMP domain-like	EAL domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	vWA-like	1	1
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	1	1
Tudor/PWWP/MBT	DNA repair protein MutS, domain III	1	1
Notch domain	Ankyrin repeat	1	1
Calponin-homology domain, CH-domain	Concanavalin A-like lectins/glucanases	1	1
Ubiquitin-like	HAD-like	1	1
Oligoxyloglucan reducing end-specific cellobiohydrolase	LDL receptor-like module	1	1
Growth factor receptor domain	TSP type-3 repeat	1	1
WW domain	dsRNA-binding domain-like	1	1
TPR-like	Chaperone J-domain	1	1
WD40 repeat-like	DPP6 N-terminal domain-like	1	1
PDZ domain-like	ClpP/crotonase	1	1
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	1	1
Ubiquitin-like	PX domain	1	1
DNA-binding protein LAG-1 (CSL)	E set domains	1	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	1	1
PurM N-terminal domain-like	Formyltransferase	1	1
Pentapeptide repeat-like	DNase I-like	1	1
XRCC4, C-terminal oligomerization domain	Immunoglobulin	1	1
Stathmin	Stathmin	1	1
Kelch motif	Fibronectin type III	1	1
WW domain	FF domain	1	1
Clavaminate synthase-like	RNI-like	1	1
F-box domain	Galactose-binding domain-like	1	1
RNA-binding domain, RBD	PABC (PABP) domain	1	1
USP8 N-terminal domain-like	Rhodanese/Cell cycle control phosphatase	1	1
ARM repeat	Ras GEF	1	1
Methionine synthase domain	Cobalamin (vitamin B12)-binding domain	1	1
ARM repeat	SAM/Pointed domain	1	1
YjgF-like	YjgF-like	1	1
Nitrite and sulphite reductase 4Fe-4S domain-like	CbiG N-terminal domain-like	1	1
FYVE/PHD zinc finger	Chromo domain-like	1	1
LDL receptor-like module	Galactose-binding domain-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Ubiquitin-like	1	1
UBA-like	KA1-like	1	1
P-loop containing nucleoside triphosphate hydrolases	Cobalamin (vitamin B12)-dependent enzymes	1	1
PUG domain-like	Ubiquitin-like	1	1
Histone-fold	Ankyrin repeat	1	1
BRCT domain	WGR domain-like	1	1
PUA domain-like	Ribosomal protein S5 domain 2-like	1	1
The spindle assembly checkpoint protein mad2	FYVE/PHD zinc finger	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Trefoil	EGF/Laminin	1	1
HAD-like	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	1	1
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	1	1
LDL receptor-like module	Fibronectin type III	1	1
Galactose-binding domain-like	Bet v1-like	1	1
SAM/Pointed domain	ArfGap/RecO-like zinc finger	1	1
EF-hand	Leucine zipper domain	1	1
Homeodomain-like	HAMP domain-like	1	1
Metallo-dependent hydrolases	Aspartate/ornithine carbamoyltransferase	1	1