SUPERFAMILY 1.75 HMM library and genome assignments server

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Domain combination pairs in Saccharomyces cerevisiae 76

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).
Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

891 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 7234
Ribonuclease H-like DNA/RNA polymerases 496
Actin-like ATPase domain Actin-like ATPase domain 379
GroES-like NAD(P)-binding Rossmann-fold domains 212
RNA-binding domain, RBD RNA-binding domain, RBD 209
Calcium ATPase, transduction domain A HAD-like 166
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 166
HAD-like Calcium ATPase, transmembrane domain M 166
ARM repeat ARM repeat 1410
P-loop containing nucleoside triphosphate hydrolases Translation proteins 149
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 133
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 137
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 126
WD40 repeat-like WD40 repeat-like 127
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 122
TPR-like TPR-like 128
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 122
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 114
Cyclin-like Cyclin-like 115
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 113
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 113
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 115
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 113
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 103
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 109
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 109
GroEL equatorial domain-like GroEL-intermediate domain like 91
GroEL equatorial domain-like GroEL apical domain-like 91
Thioredoxin-like GST C-terminal domain-like 95
GroEL-intermediate domain like GroEL apical domain-like 91
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 94
(Trans)glycosidases Glycosyl hydrolase domain 94
Protein kinase-like (PK-like) ARM repeat 99
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 85
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 85
Homeodomain-like Homeodomain-like 85
Homing endonucleases Homing endonucleases 88
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 83
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 85
EF-G C-terminal domain-like EF-G C-terminal domain-like 76
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 71
PreATP-grasp domain Rudiment single hybrid motif 76
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 71
ABC transporter transmembrane region ABC transporter transmembrane region 74
Class II aaRS and biotin synthetases Class II aaRS ABD-related 77
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 76
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 76
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 74
Chaperone J-domain HSP40/DnaJ peptide-binding domain 65
Translation proteins EF-G C-terminal domain-like 65
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 64
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 65
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 64
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 63
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 65
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 63
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 62
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 62
Thioredoxin-like Thioredoxin-like 54
Glutathione synthetase ATP-binding domain-like Single hybrid motif 54
Rudiment single hybrid motif Single hybrid motif 54
PreATP-grasp domain Single hybrid motif 54
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 53
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 54
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 54
Nucleic acid-binding proteins Translation proteins SH3-like domain 53
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 53
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 54
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 54
ENTH/VHS domain GAT-like domain 52
CRAL/TRIO N-terminal domain CRAL/TRIO domain 52
Enolase N-terminal domain-like Enolase C-terminal domain-like 51
Zn-finger domain of Sec23/24 vWA-like 54
BAR/IMD domain-like PH domain-like 52
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 54
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 53
vWA-like C-terminal, gelsolin-like domain of Sec23/24 54
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 54
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 54
Bromodomain Bromodomain 53
Translation proteins Ribosomal protein S5 domain 2-like 54
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 43
MFS general substrate transporter MFS general substrate transporter 43
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 43
Sialidases Oligoxyloglucan reducing end-specific cellobiohydrolase 43
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 42
CoA-dependent acyltransferases CoA-dependent acyltransferases 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 43
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 43
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 43
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 43
DBL homology domain (DH-domain) PH domain-like 43
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 43
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 42
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 43
P-loop containing nucleoside triphosphate hydrolases RING/U-box 41
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 42
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 43
UBA-like Ubiquitin-like 44
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 41
PA domain Zn-dependent exopeptidases 42
vWA-like Helical domain of Sec23/24 43
Zn2/Cys6 DNA-binding domain Leucine zipper domain 42
Thiolase-like Thiolase-like 43
P-loop containing nucleoside triphosphate hydrolases TGS-like 41
Aconitase iron-sulfur domain LeuD/IlvD-like 42
Nucleic acid-binding proteins Nucleic acid-binding proteins 44
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 43
beta-sandwich domain of Sec23/24 Zn-finger domain of Sec23/24 43
ARM repeat P-loop containing nucleoside triphosphate hydrolases 43
beta-sandwich domain of Sec23/24 vWA-like 43
L domain-like L domain-like 43
Aldolase post-HMGL domain-like 43
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 33
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 32
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 32
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 33
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 32
P-loop containing nucleoside triphosphate hydrolases Bromodomain 33
Ribosomal protein L6 Ribosomal protein L6 31
BRCT domain BRCT domain 33
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 33
Transmembrane di-heme cytochromes Homing endonucleases 33
F-box domain WD40 repeat-like 33
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 32
WD40 repeat-like RING/U-box 33
SMAD/FHA domain "Winged helix" DNA-binding domain 33
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 33
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 32
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 31
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 32
SH3-domain SH3-domain 33
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 31
Rhodanese/Cell cycle control phosphatase Cysteine proteinases 31
ARM repeat WD40 repeat-like 33
PH domain-like Oxysterol-binding protein-like 32
Zn-dependent exopeptidases Transferrin receptor-like dimerisation domain 31
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 32
GINS helical bundle-like PriA/YqbF domain 32
Ribokinase-like Heme oxygenase-like 31
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 31
t-snare proteins SNARE fusion complex 32
Cytochrome c oxidase subunit I-like Homing endonucleases 33
P-loop containing nucleoside triphosphate hydrolases NAD(P)-binding Rossmann-fold domains 32
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 31
Leucine zipper domain YAP1 redox domain 32
RING/U-box Cysteine proteinases 33
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
P-loop containing nucleoside triphosphate hydrolases Phosphoglycerate mutase-like 32
SMAD/FHA domain Protein kinase-like (PK-like) 32
RING/U-box RING/U-box 33
C2 domain (Calcium/lipid-binding domain, CaLB) Protein kinase-like (PK-like) 33
POZ domain POZ domain 33
ORC1-binding domain P-loop containing nucleoside triphosphate hydrolases 31
EF-hand EF-hand 33
Protein kinase-like (PK-like) KA1-like 31
Phospholipase D/nuclease Phospholipase D/nuclease 33
E set domains AMPKBI-like 32
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 31
Cullin homology domain "Winged helix" DNA-binding domain 32
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 32
PA domain Transferrin receptor-like dimerisation domain 31
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 33
"Winged helix" DNA-binding domain PH domain-like 32
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 33
FYVE/PHD zinc finger FYVE/PHD zinc finger 33
BAR/IMD domain-like SH3-domain 32
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 32
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 32
Protease propeptides/inhibitors Subtilisin-like 32
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 32
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 33
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 32
CBS-domain pair CBS-domain pair 32
ARM repeat Clathrin adaptor appendage domain 33
HCP-like TPR-like 33
Cupredoxins Cupredoxins 31
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 32
P-loop containing nucleoside triphosphate hydrolases Aminoacid dehydrogenase-like, N-terminal domain 32
CCCH zinc finger CCCH zinc finger 31
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 32
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 22
TPR-like "Winged helix" DNA-binding domain 21
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 22
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 22
Oligoxyloglucan reducing end-specific cellobiohydrolase Oligoxyloglucan reducing end-specific cellobiohydrolase 22
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 22
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 22
Glutathione synthetase ATP-binding domain-like post-HMGL domain-like 21
ENTH/VHS domain Clathrin adaptor appendage domain 21
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 22
Acid proteases Ribonuclease H-like 21
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 22
BAR/IMD domain-like GTPase activation domain, GAP 22
Rudiment single hybrid motif Aldolase 21
Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain ARM repeat 21
Cytochrome c oxidase subunit I-like DNA/RNA polymerases 21
Transcription factor IIA (TFIIA), alpha-helical domain Transcription factor IIA (TFIIA), beta-barrel domain 22
ARM repeat Hect, E3 ligase catalytic domain 21
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 22
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 22
SMAD/FHA domain RING/U-box 21
FYVE/PHD zinc finger RING/U-box 22
PreATP-grasp domain PreATP-grasp domain 22
Phosphofructokinase Phosphofructokinase 22
Rudiment single hybrid motif ClpP/crotonase 22
Rudiment single hybrid motif post-HMGL domain-like 21
Carbamate kinase-like PUA domain-like 21
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 21
Translation proteins ThrRS/AlaRS common domain 22
Clavaminate synthase-like beta-beta-alpha zinc fingers 22
SET domain SET domain 22
Kelch motif Kelch motif 22
PreATP-grasp domain Aldolase 21
PreATP-grasp domain ClpP/crotonase 22
Thioredoxin-like eEF1-gamma domain 21
Cyclophilin-like TPR-like 21
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 22
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 22
UBA-like UBA-like 22
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 22
Cullin repeat-like "Winged helix" DNA-binding domain 21
Zn2/Cys6 DNA-binding domain PYP-like sensor domain (PAS domain) 21
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 21
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 21
PH domain-like GTPase activation domain, GAP 22
FYVE/PHD zinc finger Clavaminate synthase-like 22
post-HMGL domain-like Single hybrid motif 21
Transducin (alpha subunit), insertion domain P-loop containing nucleoside triphosphate hydrolases 21
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) Protein kinase-like (PK-like) 22
PK beta-barrel domain-like PK C-terminal domain-like 21
Initiation factor IF2/eIF5b, domain 3 Translation proteins 22
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 22
SNARE-like SNARE fusion complex 21
ADC-like P-loop containing nucleoside triphosphate hydrolases 22
SH3-domain SAM/Pointed domain 21
Homeodomain-like RING/U-box 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 21
PH domain-like Protein kinase-like (PK-like) 22
DPP6 N-terminal domain-like alpha/beta-Hydrolases 21
cAMP-binding domain-like cAMP-binding domain-like 22
GST C-terminal domain-like eEF1-gamma domain 21
tRNA-binding arm Class II aaRS and biotin synthetases 22
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
Flavoproteins Riboflavin synthase domain-like 22
PreATP-grasp domain post-HMGL domain-like 21
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 22
SH3-domain PH domain-like 21
Ankyrin repeat PH domain-like 21
Retrovirus zinc finger-like domains Acid proteases 21
mRNA decapping enzyme DcpS N-terminal domain HIT-like 21
FYVE/PHD zinc finger SET domain 21
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 22
PurM N-terminal domain-like PurM C-terminal domain-like 22
HMG-box HMG-box 22
ACT-like ACT-like 22
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 22
Single hybrid motif ClpP/crotonase 22
HCP-like HCP-like 22
Voltage-gated potassium channels Voltage-gated potassium channels 22
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 22
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 22
UBC-like UBA-like 22
ARM repeat Subdomain of clathrin and coatomer appendage domain 22
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 21
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 22
Nucleotidylyl transferase Ribosomal protein L25-like 22
ClpP/crotonase ClpP/crotonase 22
NAD(P)-binding Rossmann-fold domains ACT-like 21
Cullin repeat-like Cullin homology domain 21
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 21
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 22
"Winged helix" DNA-binding domain DBL homology domain (DH-domain) 21
Glutathione synthetase ATP-binding domain-like Aldolase 21
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 22
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
Cap-Gly domain Ubiquitin-like 22
SNARE fusion complex SNARE fusion complex 21
WW domain WW domain 22
RNA-binding domain, RBD ARM repeat 21
SAP domain RING/U-box 22
ARM repeat FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 22
vWA-like SPOC domain-like 21
P-loop containing nucleoside triphosphate hydrolases HAND domain of the nucleosome remodeling ATPase ISWI 21
alpha-ketoacid dehydrogenase kinase, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
Retrovirus zinc finger-like domains Ribonuclease H-like 21
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 22
Hedgehog/intein (Hint) domain Homing endonucleases 22
Myosin S1 fragment, N-terminal domain P-loop containing nucleoside triphosphate hydrolases 22
WW domain FF domain 22
Retrovirus zinc finger-like domains DNA/RNA polymerases 21
DAK1/DegV-like DhaL-like 21
DNA-binding domain of Mlu1-box binding protein MBP1 Ankyrin repeat 21
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 21
ARM repeat Formin homology 2 domain (FH2 domain) 22
Ubiquitin-like Ubiquitin-like 22
Methylglyoxal synthase-like Cytidine deaminase-like 21
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 21
ADC-like Cdc48 domain 2-like 22
HAND domain of the nucleosome remodeling ATPase ISWI Homeodomain-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 21
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 22
E set domains Ankyrin repeat 21
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 22
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 22
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 22
HMA, heavy metal-associated domain HAD-like 22
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 22
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 21
SAM/Pointed domain PH domain-like 21
P-loop containing nucleoside triphosphate hydrolases SH3-domain 21
Zinc beta-ribbon Cyclin-like 22
PreATP-grasp domain Methylglyoxal synthase-like 22
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 21
Thioredoxin-like Ubiquitin-like 22
Class I glutamine amidotransferase-like Ribulose-phoshate binding barrel 21
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 21
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 21
RNase III domain-like dsRNA-binding domain-like 21
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 22
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 22
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 22
Single hybrid motif CoA-dependent acyltransferases 22
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 22
Acid proteases DNA/RNA polymerases 21
Sialidases Sialidases 21
Metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 21
Translational machinery components L30e-like 22
Ankyrin repeat Oxysterol-binding protein-like 21
Aldolase Single hybrid motif 21
GAT-like domain Clathrin adaptor appendage domain 21
post-HMGL domain-like 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 22
Sec63 N-terminal domain-like E set domains 22
PRTase-like PRTase-like 22
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
EF-hand Calponin-homology domain, CH-domain 11
Nucleic acid-binding proteins "Winged helix" DNA-binding domain 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Ras GEF GTPase activation domain, GAP 11
SWIB/MDM2 domain eIF1-like 11
C2 domain (Calcium/lipid-binding domain, CaLB) Cysteine-rich domain 11
WW domain Hect, E3 ligase catalytic domain 11
Aldolase Aminoacid dehydrogenase-like, N-terminal domain 11
F-box domain RCC1/BLIP-II 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes CBS-domain pair 11
YbaK/ProRS associated domain Class II aaRS ABD-related 11
HR1 repeat C2 domain (Calcium/lipid-binding domain, CaLB) 11
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 11
Homodimeric domain of signal transducing histidine kinase CheY-like 11
Glucocorticoid receptor-like (DNA-binding domain) Glucocorticoid receptor-like (DNA-binding domain) 11
all-alpha NTP pyrophosphatases ALDH-like 11
PP2C-like Nucleotide cyclase 11
TGS-like Class II aaRS ABD-related 11
Ras GEF Ras GEF 11
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 11
P-loop containing nucleoside triphosphate hydrolases Aldolase 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Phosphofructokinase 11
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 11
SpoIIaa-like BAG domain 11
Ubiquitin-like Zn-binding ribosomal proteins 11
PreATP-grasp domain Aspartate/ornithine carbamoyltransferase 11
Tetrahydrobiopterin biosynthesis enzymes-like 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK 11
Class I glutamine amidotransferase-like ADC synthase 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Trimeric LpxA-like enzymes ARM repeat 11
BAR/IMD domain-like BAR/IMD domain-like 11
PreATP-grasp domain Metallo-dependent hydrolases 11
P-loop containing nucleoside triphosphate hydrolases vWA-like 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
NTF2-like UBA-like 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
TPR-like Metallo-dependent phosphatases 11
Dehydroquinate synthase-like Aminoacid dehydrogenase-like, N-terminal domain 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
DNA clamp DNA clamp 11
PLP-dependent transferases PLP-dependent transferases 11
GST C-terminal domain-like Nucleic acid-binding proteins 11
Chaperone J-domain E set domains 11
PUA domain-like eIF1-like 11
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 11
Dom34/Pelota N-terminal domain-like Translational machinery components 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
PYP-like sensor domain (PAS domain) Protein kinase-like (PK-like) 11
FYVE/PHD zinc finger Rabenosyn-5 Rab-binding domain-like 11
Glutathione synthetase ATP-binding domain-like PurM N-terminal domain-like 11
E set domains Glycosyl hydrolase domain 11
PH domain-like EF-hand 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
UBA-like XPC-binding domain 11
UBC-like Endosomal sorting complex assembly domain 11
Nucleic acid-binding proteins eIF2alpha middle domain-like 11
Pseudouridine synthase Cytidine deaminase-like 11
HR1 repeat Protein kinase-like (PK-like) 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
CoA-dependent acyltransferases NAD(P)-binding Rossmann-fold domains 11
P-loop containing nucleoside triphosphate hydrolases Prismane protein-like 11
E set domains E set domains 11
beta-sandwich domain of Sec23/24 Histone-fold 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
YbaK/ProRS associated domain Class II aaRS and biotin synthetases 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 11
Metallo-dependent hydrolases Aspartate/ornithine carbamoyltransferase 11
RING/U-box Quinoprotein alcohol dehydrogenase-like 11
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 11
P-loop containing nucleoside triphosphate hydrolases EF-hand 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
FYVE/PHD zinc finger Elongation factor TFIIS domain 2 11
Metalloproteases ("zincins"), catalytic domain ARM repeat 11
Amidase signature (AS) enzymes Cyclophilin-like 11
Alpha subunit of glutamate synthase, C-terminal domain Nucleotide-binding domain 11
Inhibitor of apoptosis (IAP) repeat Inhibitor of apoptosis (IAP) repeat 11
FYVE/PHD zinc finger SAICAR synthase-like 11
Dehydroquinate synthase-like Aldolase 11
Zinc beta-ribbon Zinc beta-ribbon 11
PurS-like PurM C-terminal domain-like 11
TPR-like F-box domain 11
Calponin-homology domain, CH-domain GTPase activation domain, GAP 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
HAD-like BRCT domain 11
Ribonuclease H-like Ribonuclease H-like 11
Fibronectin type III BRCT domain 11
Cysteine-rich domain Cysteine-rich domain 11
SH3-domain Cysteine proteinases 11
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Chaperone J-domain CSL zinc finger 11
Galactose mutarotase-like (Trans)glycosidases 11
Amidase signature (AS) enzymes Glutathione synthetase ATP-binding domain-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
PH domain-like BEACH domain 11
Class I glutamine amidotransferase-like PreATP-grasp domain 11
Protein prenylyltransferase HCP-like 11
Histone-fold ARM repeat 11
BAH domain P-loop containing nucleoside triphosphate hydrolases 11
PreATP-grasp domain PurM N-terminal domain-like 11
Pre-PUA domain PUA domain-like 11
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 11
Adenine nucleotide alpha hydrolases-like YjgF-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
Subtilisin-like Galactose-binding domain-like 11
Cysteine-rich domain Protein kinase-like (PK-like) 11
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 11
L domain-like PP2C-like 11
Ran binding protein zinc finger-like "Winged helix" DNA-binding domain 11
Flavoproteins Nitrite and sulphite reductase 4Fe-4S domain-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
C2 domain (Calcium/lipid-binding domain, CaLB) Hect, E3 ligase catalytic domain 11
Glutathione synthetase ATP-binding domain-like PH0987 N-terminal domain-like 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
PurS-like FGAM synthase PurL, linker domain 11
Eukaryotic type KH-domain (KH-domain type I) Clathrin adaptor appendage domain 11
SNARE-like P-loop containing nucleoside triphosphate hydrolases 11
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 11
SAM/Pointed domain Ubiquitin-like 11
PH0987 N-terminal domain-like Single hybrid motif 11
MIT domain P-loop containing nucleoside triphosphate hydrolases 11
Siroheme synthase middle domains-like Tetrapyrrole methylase 11
TGS-like Class II aaRS and biotin synthetases 11
GST C-terminal domain-like Nucleotidylyl transferase 11
Ubiquitin-like XPC-binding domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Periplasmic binding protein-like II ACT-like 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
UBA-like SMR domain-like 11
P-loop containing nucleoside triphosphate hydrolases PRTase-like 11
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 11
NAD(P)-binding Rossmann-fold domains Cysteine proteinases 11
TPR-like Chaperone J-domain 11
Cytochrome b5-like heme/steroid binding domain FMN-linked oxidoreductases 11
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 11
UBC-like Protein kinase-like (PK-like) 11
SNARE-like Domain of the SRP/SRP receptor G-proteins 11
L9 N-domain-like Ribonuclease H-like 11
Elongation factor TFIIS domain 2 Zinc beta-ribbon 11
FYVE/PHD zinc finger Homeodomain-like 11
Amidase signature (AS) enzymes Single hybrid motif 11
FabD/lysophospholipase-like Thioesterase/thiol ester dehydrase-isomerase 11
Acid proteases UBA-like 11
E set domains (Trans)glycosidases 11
Clathrin heavy-chain terminal domain ARM repeat 11
ARM repeat RING/U-box 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
PX domain GTPase activation domain, GAP 11
P-loop containing nucleoside triphosphate hydrolases E set domains 11
PX domain Phospholipase D/nuclease 11
FMN-binding split barrel UbiD C-terminal domain-like 11
RNI-like RNI-like 11
Class II aaRS and biotin synthetases Class II aaRS and biotin synthetases 11
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 11
Amidase signature (AS) enzymes Rudiment single hybrid motif 11
NAD(P)-binding Rossmann-fold domains 4'-phosphopantetheinyl transferase 11
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 11
PX domain PH domain-like 11
BRCT domain DNA/RNA polymerases 11
(Trans)glycosidases Six-hairpin glycosidases 11
L domain-like DNase I-like 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Rudiment single hybrid motif PH0987 N-terminal domain-like 11
Homeodomain-like beta-sandwich domain of Sec23/24 11
HIT-like HIT-like 11
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Periplasmic binding protein-like II GlnB-like 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
C2 domain (Calcium/lipid-binding domain, CaLB) WW domain 11
TK C-terminal domain-like Flavoproteins 11
CoA-dependent acyltransferases Acetyl-CoA synthetase-like 11
Nucleotide-binding domain Nucleotide-binding domain 11
Ribulose-phoshate binding barrel Tryptophan synthase beta subunit-like PLP-dependent enzymes 11
CoA-dependent acyltransferases ACP-like 11
Quinoprotein alcohol dehydrogenase-like Protein kinase-like (PK-like) 11
Rudiment single hybrid motif PurM N-terminal domain-like 11
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 11
DEK C-terminal domain SWIB/MDM2 domain 11
"Winged helix" DNA-binding domain CheY-like 11
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 11
SET domain WW domain 11
Acyl-CoA N-acyltransferases (Nat) Bromodomain 11
Ras GEF PH domain-like 11
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 11
Endosomal sorting complex assembly domain VPS28 C-terminal domain-like 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
GST C-terminal domain-like eEF-1beta-like 11
Zinc-binding domain of translation initiation factor 2 beta ARM repeat 11
Carbamoyl phosphate synthetase, large subunit connection domain Aspartate/ornithine carbamoyltransferase 11
Thiolase-like 4'-phosphopantetheinyl transferase 11
Tetrahydrobiopterin biosynthesis enzymes-like Dihydropteroate synthetase-like 11
Acetyl-CoA synthetase-like NAD(P)-binding Rossmann-fold domains 11
BSD domain-like BSD domain-like 11
BRCT domain Homeodomain-like 11
WD40 repeat-like Bacterial exopeptidase dimerisation domain 11
Metalloproteases ("zincins"), catalytic domain Mannose-binding lectins 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
Nucleotidylyl transferase Nucleotidylyl transferase 11
Cyclophilin-like PH0987 N-terminal domain-like 11
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Nucleotide-diphospho-sugar transferases ARM repeat 11
ENTH/VHS domain FYVE/PHD zinc finger 11
L9 N-domain-like L9 N-domain-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 11
YjgF-like YjgF-like 11
PH domain-like CAD & PB1 domains 11
Galactose-binding domain-like Galactose-binding domain-like 11
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 11
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Chromo domain-like Homeodomain-like 11
Amidase signature (AS) enzymes PreATP-grasp domain 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 11
PUA domain-like Nucleotidylyl transferase 11
PH domain-like PH domain-like 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
L domain-like NTF2-like 11
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK Dihydropteroate synthetase-like 11
Retrovirus zinc finger-like domains Clathrin adaptor appendage domain 11
Arp2/3 complex subunits Arp2/3 complex subunits 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Pseudouridine synthase PUA domain-like 11
FF domain FF domain 11
RNI-like Ubiquitin-like 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Galactose oxidase, central domain 11
HisI-like all-alpha NTP pyrophosphatases 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Metallo-dependent hydrolases 11
Protein kinase-like (PK-like) WD40 repeat-like 11
EPT/RTPC-like P-loop containing nucleoside triphosphate hydrolases 11
FabD/lysophospholipase-like Thiolase-like 11
Tex N-terminal region-like Ribonuclease H-like 11
ArfGap/RecO-like zinc finger UBA-like 11
FabD/lysophospholipase-like FabD/lysophospholipase-like 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
DBL homology domain (DH-domain) CAD & PB1 domains 11
FYSH domain Hypothetical protein AF0491, middle domain 11
PH domain-like WD40 repeat-like 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Amidase signature (AS) enzymes PH0987 N-terminal domain-like 11
PLP-binding barrel Alanine racemase C-terminal domain-like 11
Tex N-terminal region-like SH2 domain 11
EPT/RTPC-like Aminoacid dehydrogenase-like, N-terminal domain 11
vWA-like Cysteine-rich domain 11
PurS-like Class I glutamine amidotransferase-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Aspartate/ornithine carbamoyltransferase 11
WD40 repeat-like Nucleoporin domain 11
Eukaryotic type KH-domain (KH-domain type I) Retrovirus zinc finger-like domains 11
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 11
Clc chloride channel CBS-domain pair 11
ENTH/VHS domain SH3-domain 11
UBA-like P-loop containing nucleoside triphosphate hydrolases 11
Class I glutamine amidotransferase-like Methylglyoxal synthase-like 11
Globin-like Riboflavin synthase domain-like 11
Nucleic acid-binding proteins BRCT domain 11
HisI-like ALDH-like 11
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 11
Supernatant protein factor (SPF), C-terminal domain Oxysterol-binding protein-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Thiamin diphosphate-binding fold (THDP-binding) Nitrite and sulphite reductase 4Fe-4S domain-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Glutathione synthetase ATP-binding domain-like 11
TK C-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
HR1 repeat Cysteine-rich domain 11
WD40 repeat-like Putative isomerase YbhE 11
Retrovirus zinc finger-like domains RING/U-box 11
EF-hand Mitochondrial carrier 11
BRCT domain Lesion bypass DNA polymerase (Y-family), little finger domain 11
HMA, heavy metal-associated domain Cu,Zn superoxide dismutase-like 11
Tex N-terminal region-like RuvA domain 2-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Carbamoyl phosphate synthetase, large subunit connection domain 11
Calcium-dependent phosphotriesterase RING/U-box 11
FYVE/PHD zinc finger GroEL apical domain-like 11
FMN-linked oxidoreductases Nucleotide-binding domain 11
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain WD40 repeat-like 11
UBC-like P-loop containing nucleoside triphosphate hydrolases 11
Aldolase NAD(P)-binding Rossmann-fold domains 11
Chaperone J-domain beta-beta-alpha zinc fingers 11
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 11
Activator of Hsp90 ATPase, Aha1 Bet v1-like 11
UBC-like Class II aaRS and biotin synthetases 11
"Winged helix" DNA-binding domain RNA-binding domain, RBD 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
TATA-box binding protein-like DNA-glycosylase 11
Cysteine proteinases UBA-like 11
PH domain-like BSD domain-like 11
PreATP-grasp domain PH0987 N-terminal domain-like 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Hypothetical protein c14orf129, hspc210 TPR-like 11
WD40 repeat-like Peptidase/esterase 'gauge' domain 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Ribonuclease H-like SH2 domain 11
EPT/RTPC-like NAD(P)-binding Rossmann-fold domains 11
F-box domain RNI-like 11
Alpha subunit of glutamate synthase, C-terminal domain alpha-helical ferredoxin 11
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 11
L30e-like alpha/beta knot 11
TATA-box binding protein-like TATA-box binding protein-like 11
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 11
Flavoproteins Nitrite/Sulfite reductase N-terminal domain-like 11
Protein kinase-like (PK-like) Polo-box domain 11
Glutathione synthetase ATP-binding domain-like Cyclophilin-like 11
Nucleotidylyl transferase P-loop containing nucleoside triphosphate hydrolases 11
Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like 11
Regulator of G-protein signaling, RGS PX domain 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Rudiment single hybrid motif Cyclophilin-like 11
Leukotriene A4 hydrolase N-terminal domain ARM repeat 11
Rudiment single hybrid motif N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
"Winged helix" DNA-binding domain Regulator of G-protein signaling, RGS 11
DUSP-like Cysteine proteinases 11
C2 domain (Calcium/lipid-binding domain, CaLB) ARM repeat 11
PreATP-grasp domain Cyclophilin-like 11
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 11
Flavoproteins Radical SAM enzymes 11
DNA polymerase beta, N-terminal domain-like Restriction endonuclease-like 11
P-loop containing nucleoside triphosphate hydrolases Homing endonucleases 11
Cysteine proteinases Ribonuclease H-like 11
PX domain BAR/IMD domain-like 11
CCCH zinc finger RING/U-box 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
WW domain FKBP-like 11
SMAD/FHA domain SMAD/FHA domain 11
Nucleic acid-binding proteins TPR-like 11
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Nucleotide-binding domain 11
Ribonuclease H-like HRDC-like 11
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
PurS-like PurM N-terminal domain-like 11
RING/U-box RNA-binding domain, RBD 11
Homing endonucleases C-terminal domain of alpha and beta subunits of F1 ATP synthase 11
RING/U-box R3H domain 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
EF-hand UBA-like 11
FMN-linked oxidoreductases alpha-helical ferredoxin 11
VPS9 domain UBA-like 11
Class I glutamine amidotransferase-like Aspartate/ornithine carbamoyltransferase 11
Cyclophilin-like Single hybrid motif 11
WD40 repeat-like YVTN repeat-like/Quinoprotein amine dehydrogenase 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
Class I glutamine amidotransferase-like Metallo-dependent hydrolases 11
FAS1 domain FAS1 domain 11
Nucleotidylyl transferase tRNA-binding arm 11
EPT/RTPC-like Aldolase 11
Rudiment single hybrid motif PurM C-terminal domain-like 11
BAG domain cAMP-binding domain-like 11
Taf5 N-terminal domain-like WD40 repeat-like 11
GroEL apical domain-like SAICAR synthase-like 11
PIN domain-like Nucleic acid-binding proteins 11
TK C-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
Sec7 domain ARM repeat 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
Restriction endonuclease-like RuvA domain 2-like 11
Glucocorticoid receptor-like (DNA-binding domain) GTPase activation domain, GAP 11
Methylglyoxal synthase-like Aspartate/ornithine carbamoyltransferase 11
PH domain-like Cullin repeat-like 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
PX domain SNARE fusion complex 11
ACP-like NAD(P)-binding Rossmann-fold domains 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains Thiolase-like 11
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III Riboflavin synthase domain-like 11
PurM N-terminal domain-like Class I glutamine amidotransferase-like 11
Protein prenylyltransferase TPR-like 11
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 11
Ran binding protein zinc finger-like Ran binding protein zinc finger-like 11
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 11
PH domain-like Ran binding protein zinc finger-like 11
Glutathione synthetase ATP-binding domain-like N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
N-terminal domain of adenylylcyclase associated protein, CAP C-terminal domain of adenylylcyclase associated protein 11
TGS-like ThrRS/AlaRS common domain 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
ARID-like FYVE/PHD zinc finger 11
UBA-like Thioredoxin-like 11
FabD/lysophospholipase-like 4'-phosphopantetheinyl transferase 11
PreATP-grasp domain N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 11
UROD/MetE-like UROD/MetE-like 11
RNA-binding domain, RBD DPP6 N-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
ENTH/VHS domain I/LWEQ domain 11
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Glutathione synthetase ATP-binding domain-like Aspartate/ornithine carbamoyltransferase 11
POZ domain Skp1 dimerisation domain-like 11
Carbamoyl phosphate synthetase, large subunit connection domain Metallo-dependent hydrolases 11
UBA-like TPR-like 11
Tricorn protease domain 2 NHL repeat 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
PreATP-grasp domain PurM C-terminal domain-like 11
Acetyl-CoA synthetase-like ACP-like 11
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 11
alpha-helical ferredoxin Nucleotide-binding domain 11
Ypt/Rab-GAP domain of gyp1p EF-hand 11
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 11
UBC-like Ribosomal protein S5 domain 2-like 11
Ankyrin repeat PLC-like phosphodiesterases 11
RNA-binding domain, RBD Class II aaRS ABD-related 11
PH domain-like PLC-like phosphodiesterases 11
TK C-terminal domain-like Riboflavin synthase domain-like 11
TRAF domain-like Cysteine proteinases 11
L domain-like UBA-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Rap30/74 interaction domains "Winged helix" DNA-binding domain 11
Class I glutamine amidotransferase-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Methylglyoxal synthase-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Nucleotidyltransferase Poly A polymerase C-terminal region-like 11
Cap-Gly domain RNI-like 11
SAM/Pointed domain Protein kinase-like (PK-like) 11
FabD/lysophospholipase-like NAD(P)-binding Rossmann-fold domains 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
YbaK/ProRS associated domain C-terminal domain of ProRS 11
TPR-like HSP20-like chaperones 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
RibA-like RibA-like 11
PH domain-like C2 domain (Calcium/lipid-binding domain, CaLB) 11
L domain-like Nucleotide cyclase 11
NAD(P)-binding Rossmann-fold domains Thioesterase/thiol ester dehydrase-isomerase 11
Protein kinase-like (PK-like) CheY-like 11
TPR-like RNI-like 11
RNA-binding domain, RBD PABC (PABP) domain 11
Thiamin diphosphate-binding fold (THDP-binding) Flavoproteins 11
SH3-domain CAD & PB1 domains 11
RING/U-box UBA-like 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Ubiquitin-like Cysteine proteinases 11
Class I glutamine amidotransferase-like Glutathione synthetase ATP-binding domain-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Glutathione synthetase ATP-binding domain-like Metallo-dependent hydrolases 11
GroES-like GroES-like 11
SH3-domain Ras GEF 11
Ankyrin repeat POZ domain 11
ORC1-binding domain ORC1-binding domain 11
Ubiquitin-like Acid proteases 11
Putative DNA-binding domain Putative DNA-binding domain 11
Chromo domain-like Chromo domain-like 11
UBA-like Chaperone J-domain 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Elongation factor TFIIS domain 2 11
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 11
PX domain CAD & PB1 domains 11
GST C-terminal domain-like Ribosomal protein L25-like 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
Concanavalin A-like lectins/glucanases P-domain of calnexin/calreticulin 11
Thiamin phosphate synthase Ribokinase-like 11
SurE-like Glutathione synthetase ATP-binding domain-like 11
PH domain-like UDP-Glycosyltransferase/glycogen phosphorylase 11
Dehydroquinate synthase-like P-loop containing nucleoside triphosphate hydrolases 11
Supernatant protein factor (SPF), C-terminal domain PH domain-like 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 11
Rap30/74 interaction domains Rap30/74 interaction domains 11
Tropomyosin Tropomyosin 11
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 11
PurM C-terminal domain-like Class I glutamine amidotransferase-like 11
Galactose oxidase, central domain Galactose oxidase, central domain 11
PUA domain-like SWIB/MDM2 domain 11
(Trans)glycosidases Chitinase insertion domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Cadherin-like Cadherin-like 11
Metallo-hydrolase/oxidoreductase SCP-like 11
Smc hinge domain Tropomyosin 11
Cyclophilin-like Cyclophilin-like 11
EF-hand PLC-like phosphodiesterases 11
C2 domain (Calcium/lipid-binding domain, CaLB) GTPase activation domain, GAP 11
Dehydroquinate synthase-like EPT/RTPC-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
ENTH/VHS domain RNA-binding domain, RBD 11
PDZ domain-like PDZ domain-like 11
Protein kinase-like (PK-like) Class II aaRS and biotin synthetases 11
Ribosomal L27 protein-like Nucleic acid-binding proteins 11
Methylglyoxal synthase-like Metallo-dependent hydrolases 11
Translation proteins SH3-like domain Translation proteins SH3-like domain 11
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 11
Dehydroquinate synthase-like NAD(P)-binding Rossmann-fold domains 11
RuvA domain 2-like SH2 domain 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
Hedgehog/intein (Hint) domain C-terminal domain of alpha and beta subunits of F1 ATP synthase 11
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 11
cAMP-binding domain-like FabD/lysophospholipase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) alpha-helical ferredoxin 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
Quinoprotein alcohol dehydrogenase-like Ribonuclease H-like 11
PH domain-like (Phosphotyrosine protein) phosphatases II 11
Trypsin-like serine proteases PDZ domain-like 11
"Winged helix" DNA-binding domain E set domains 11
Ribonuclease H-like RuvA domain 2-like 11
Dcp2 domain-like Nudix 11
PAH2 domain PAH2 domain 11
Surp module (SWAP domain) Surp module (SWAP domain) 11
BRCT domain post-AAA+ oligomerization domain-like 11
N-terminal domain of alpha and beta subunits of F1 ATP synthase Homing endonucleases 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Quinoprotein alcohol dehydrogenase-like Cysteine proteinases 11
NAD(P)-binding Rossmann-fold domains Galactose mutarotase-like 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
Dom34/Pelota N-terminal domain-like L30e-like 11
N-terminal domain of alpha and beta subunits of F1 ATP synthase Hedgehog/intein (Hint) domain 11
Actin depolymerizing proteins Actin depolymerizing proteins 11
Translation proteins Translation proteins 11
Ribosomal L27 protein-like Eukaryotic type KH-domain (KH-domain type I) 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain PreATP-grasp domain 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
Trypsin-like serine proteases Trypsin-like serine proteases 11
SH3-domain PX domain 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 11
Chaperone J-domain Sec63 N-terminal domain-like 11
BRCT domain P-loop containing nucleoside triphosphate hydrolases 11
Thiamin diphosphate-binding fold (THDP-binding) Nitrite/Sulfite reductase N-terminal domain-like 11
ISP transmembrane anchor ISP domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Globin-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
TK C-terminal domain-like Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 11
RNA-binding domain, RBD Ran binding protein zinc finger-like 11
Galactose mutarotase-like Six-hairpin glycosidases 11
P-loop containing nucleoside triphosphate hydrolases Hedgehog/intein (Hint) domain 11
Glutathione synthetase ATP-binding domain-like PurM C-terminal domain-like 11
Polo-box domain Polo-box domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
VPS9 domain Pseudo ankyrin repeat-like 11
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 11
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 11
SpoIIaa-like cAMP-binding domain-like 11
Class I glutamine amidotransferase-like Class II aaRS and biotin synthetases 11
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
TK C-terminal domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 11
Carbamate kinase-like ACT-like 11
Actin depolymerizing proteins SH3-domain 11
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
PH domain-like ARM repeat 11
WD40 repeat-like Zn-dependent exopeptidases 11
BEACH domain WD40 repeat-like 11
Rhodanese/Cell cycle control phosphatase (Phosphotyrosine protein) phosphatases II 11

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