SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Domain combination pairs in Glycine max v109

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

  • For a list of unique full length architectures for this genome click here (can be slow).

Add or remove domain pairs

The links below permit the addition or removal of specific sets of domain combination pairs.


Jump to [ Top of page · Add/remove domain pairs · Domain combination pairs ]

Add or remove genomes

Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.

Add or remove genomes:
Include genomes:
Exclude genomes:


Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes ]

Domain combination pairs

1574 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
L domain-like Protein kinase-like (PK-like) 47248
P-loop containing nucleoside triphosphate hydrolases L domain-like 35856
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 35870
L domain-like L domain-like 29779
L domain-like RNI-like 22569
RNA-binding domain, RBD RNA-binding domain, RBD 20624
Toll/Interleukin receptor TIR domain P-loop containing nucleoside triphosphate hydrolases 15428
alpha-D-mannose-specific plant lectins Protein kinase-like (PK-like) 14513
TPR-like TPR-like 13334
Actin-like ATPase domain Actin-like ATPase domain 13119
Toll/Interleukin receptor TIR domain L domain-like 13019
RNI-like Protein kinase-like (PK-like) 12035
Thioredoxin-like GST C-terminal domain-like 1157
HAD-like Calcium ATPase, transmembrane domain M 11218
Calcium ATPase, transduction domain A HAD-like 11218
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 1128
DNA/RNA polymerases Ribonuclease H-like 11140
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 11117
F-box domain RNI-like 10810
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 10722
Cupredoxins Cupredoxins 1079
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 1028
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 10219
NAD(P)-binding Rossmann-fold domains GroES-like 997
RING/U-box ARM repeat 9710
"Winged helix" DNA-binding domain L domain-like 9115
Toll/Interleukin receptor TIR domain "Winged helix" DNA-binding domain 9014
Cyclin-like Cyclin-like 907
RNI-like RNI-like 8930
ARM repeat ARM repeat 8934
Thiolase-like Thiolase-like 882
Plant invertase/pectin methylesterase inhibitor Pectin lyase-like 883
Barwin-like endoglucanases PHL pollen allergen 861
ABC transporter transmembrane region ABC transporter transmembrane region 8511
CRAL/TRIO N-terminal domain CRAL/TRIO domain 859
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 8210
Galactose-binding domain-like (Trans)glycosidases 7514
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 7111
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 7010
Concanavalin A-like lectins/glucanases Protein kinase-like (PK-like) 698
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 699
Protein kinase-like (PK-like) EF-hand 663
F-box domain Kelch motif 645
Homeodomain-like Homeodomain-like 6313
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 5811
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 589
Voltage-gated potassium channels cAMP-binding domain-like 587
(Trans)glycosidases Glycosyl hydrolase domain 5712
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 578
C2 domain (Calcium/lipid-binding domain, CaLB) C2 domain (Calcium/lipid-binding domain, CaLB) 5610
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 569
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 559
Riboflavin synthase domain-like Ferredoxin reductase-like, C-terminal NADP-linked domain 5513
P-loop containing nucleoside triphosphate hydrolases Translation proteins 5416
Eukaryotic type KH-domain (KH-domain type I) Eukaryotic type KH-domain (KH-domain type I) 5317
"Winged helix" DNA-binding domain S-adenosyl-L-methionine-dependent methyltransferases 531
Bet v1-like Bet v1-like 528
Chaperone J-domain HSP40/DnaJ peptide-binding domain 5210
DNA-binding pseudobarrel domain CAD & PB1 domains 524
DNA-binding domain DNA-binding domain 515
Lipase/lipooxygenase domain (PLAT/LH2 domain) Lipoxigenase 514
CCCH zinc finger CCCH zinc finger 5017
P-loop containing nucleoside triphosphate hydrolases RNI-like 4921
Acid proteases DNA/RNA polymerases 4915
Homeodomain-like Bet v1-like 495
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 484
Galactose-binding domain-like Galactose-binding domain-like 474
Acid proteases Ribonuclease H-like 4612
ENTH/VHS domain GAT-like domain 464
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 4411
Ribonuclease H-like Ribonuclease H-like 4310
Ubiquitin-like Ubiquitin-like 4312
beta-beta-alpha zinc fingers beta-beta-alpha zinc fingers 4212
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 4210
GroEL equatorial domain-like GroEL apical domain-like 418
Thioredoxin-like Thioredoxin-like 4114
GroEL-intermediate domain like GroEL apical domain-like 407
GroEL equatorial domain-like GroEL-intermediate domain like 407
RING/U-box vWA-like 409
Nucleic acid-binding proteins Nucleic acid-binding proteins 4021
RING/U-box RING/U-box 3919
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 388
SNARE-like SNARE fusion complex 372
Nucleotidyltransferase PAP/OAS1 substrate-binding domain 376
ACT-like ACT-like 3712
Ypt/Rab-GAP domain of gyp1p Ypt/Rab-GAP domain of gyp1p 375
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 367
WD40 repeat-like WD40 repeat-like 3613
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 356
Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases 355
(Trans)glycosidases Beta-D-glucan exohydrolase, C-terminal domain 343
WRKY DNA-binding domain WRKY DNA-binding domain 344
Periplasmic binding protein-like I Periplasmic binding protein-like II 343
Nucleic acid-binding proteins Retrovirus zinc finger-like domains 343
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 343
Glucocorticoid receptor-like (DNA-binding domain) Glucocorticoid receptor-like (DNA-binding domain) 339
Phospholipase D/nuclease Phospholipase D/nuclease 3213
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 324
Glucocorticoid receptor-like (DNA-binding domain) AN1-like Zinc finger 321
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 327
GroES-like GroES-like 313
CBS-domain pair CBS-domain pair 3110
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 315
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 307
Ran binding protein zinc finger-like Ran binding protein zinc finger-like 3011
F-box domain Tubby C-terminal domain-like 304
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 307
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase CheY-like 296
FYVE/PHD zinc finger FYVE/PHD zinc finger 2911
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 296
Homodimeric domain of signal transducing histidine kinase CheY-like 295
SNARE-like Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor 292
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 285
UBA-like Ubiquitin-like 289
F-box domain Galactose oxidase, central domain 283
TRAF domain-like POZ domain 284
CHY zinc finger-like Zinc hairpin stack 285
RING/U-box Nucleotide-diphospho-sugar transferases 282
RNA-binding domain, RBD Retrovirus zinc finger-like domains 283
CheY-like Homeodomain-like 284
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 283
Thioesterase/thiol ester dehydrase-isomerase Thioesterase/thiol ester dehydrase-isomerase 275
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 273
F-box domain L domain-like 276
Terpenoid cyclases/Protein prenyltransferases Terpenoid synthases 272
UDP-Glycosyltransferase/glycogen phosphorylase HAD-like 274
ARM repeat Protein kinase-like (PK-like) 2713
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 2711
Zinc hairpin stack RING/U-box 275
CHY zinc finger-like RING/U-box 264
PK beta-barrel domain-like PK C-terminal domain-like 262
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 2610
Arabinanase/levansucrase/invertase Concanavalin A-like lectins/glucanases 262
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 254
Subtilisin-like PA domain 254
EF-hand EF-hand 245
DNase I-like DNA/RNA polymerases 2417
EF-G C-terminal domain-like EF-G C-terminal domain-like 2412
P-loop containing nucleoside triphosphate hydrolases RING/U-box 245
Adenine nucleotide alpha hydrolases-like Protein kinase-like (PK-like) 244
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 2412
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 243
Translation proteins EF-G C-terminal domain-like 2412
Cullin homology domain "Winged helix" DNA-binding domain 244
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 232
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 234
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain SAICAR synthase-like 238
Cullin repeat-like Cullin homology domain 234
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 235
PAZ domain Ribonuclease H-like 223
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 228
PGBD-like Metalloproteases ("zincins"), catalytic domain 222
Cullin repeat-like "Winged helix" DNA-binding domain 223
DNA-binding pseudobarrel domain DNA-binding pseudobarrel domain 222
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 225
RING/U-box TRAF domain-like 222
EF-hand Riboflavin synthase domain-like 226
FAS1 domain FAS1 domain 224
C2 domain (Calcium/lipid-binding domain, CaLB) Phospholipase D/nuclease 216
Ankyrin repeat RING/U-box 215
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 219
CCCH zinc finger WD40 repeat-like 212
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 215
UBA-like UBA-like 216
NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 218
RING/U-box Protein kinase-like (PK-like) 216
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 2111
Translation proteins SH3-like domain Nucleic acid-binding proteins 214
CCCH zinc finger RNA-binding domain, RBD 206
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 204
EF-hand Ferredoxin reductase-like, C-terminal NADP-linked domain 204
MFS general substrate transporter MFS general substrate transporter 202
Concanavalin A-like lectins/glucanases P-domain of calnexin/calreticulin 201
CAD & PB1 domains Protein kinase-like (PK-like) 201
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 203
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 202
PH domain-like FYVE/PHD zinc finger 204
dsRNA-binding domain-like dsRNA-binding domain-like 205
Cryptochrome/photolyase, N-terminal domain Cryptochrome/photolyase FAD-binding domain 193
beta-sandwich domain of Sec23/24 vWA-like 198
PH domain-like RCC1/BLIP-II 194
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 194
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 195
Acid proteases Saposin 191
RCC1/BLIP-II FYVE/PHD zinc finger 194
FYVE/PHD zinc finger Acyl-CoA N-acyltransferases (Nat) 195
Single hybrid motif CoA-dependent acyltransferases 196
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 187
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 186
UBA-like XPC-binding domain 186
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 185
HCP-like HCP-like 1810
FKBP-like TPR-like 182
Protein kinase-like (PK-like) TPR-like 181
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 186
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 183
"Winged helix" DNA-binding domain E2F-DP heterodimerization region 173
Actin depolymerizing proteins Actin depolymerizing proteins 176
NTF2-like RNA-binding domain, RBD 172
DHS-like NAD/FAD-binding domain Thiamin diphosphate-binding fold (THDP-binding) 174
Ubiquitin-like BAG domain 174
t-snare proteins SNARE fusion complex 172
Terpenoid cyclases/Protein prenyltransferases Terpenoid cyclases/Protein prenyltransferases 174
Class II aaRS and biotin synthetases Class II aaRS ABD-related 1710
Protease propeptides/inhibitors Subtilisin-like 173
Amine oxidase N-terminal region Amine oxidase catalytic domain 175
YhbY-like YhbY-like 168
Zn-finger domain of Sec23/24 beta-sandwich domain of Sec23/24 167
Ankyrin repeat Protein kinase-like (PK-like) 164
ARM repeat Clathrin adaptor appendage domain 165
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 1610
ARM repeat Hect, E3 ligase catalytic domain 166
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase HSP90 C-terminal domain 164
Zn-finger domain of Sec23/24 vWA-like 167
EF-hand C2 domain (Calcium/lipid-binding domain, CaLB) 164
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 1610
Ubiquitin-like XPC-binding domain 164
Protein kinase-like (PK-like) WD40 repeat-like 165
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 165
Ribosomal protein S5 domain 2-like HSP90 C-terminal domain 164
Transducin (alpha subunit), insertion domain P-loop containing nucleoside triphosphate hydrolases 162
vWA-like Helical domain of Sec23/24 156
Calponin-homology domain, CH-domain P-loop containing nucleoside triphosphate hydrolases 154
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 156
E set domains Ankyrin repeat 153
Amine oxidase N-terminal region Amine oxidase N-terminal region 154
HMA, heavy metal-associated domain HAD-like 159
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 155
Retrovirus zinc finger-like domains DNA/RNA polymerases 1512
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 155
Zn-finger domain of Sec23/24 Helical domain of Sec23/24 156
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 155
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 159
beta-sandwich domain of Sec23/24 Helical domain of Sec23/24 156
PUA domain-like SET domain 154
GAF domain-like Homodimeric domain of signal transducing histidine kinase 154
ISP domain Bet v1-like 143
Retrovirus zinc finger-like domains Retrovirus zinc finger-like domains 146
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 142
ADC-like Cdc48 domain 2-like 142
P-loop containing nucleoside triphosphate hydrolases EF-hand 142
Cdc48 domain 2-like P-loop containing nucleoside triphosphate hydrolases 142
PAP/OAS1 substrate-binding domain PAP/Archaeal CCA-adding enzyme, C-terminal domain 142
RNA-binding domain, RBD PABC (PABP) domain 143
"Winged helix" DNA-binding domain RNA-binding domain, RBD 145
F1F0 ATP synthase subunit C F1F0 ATP synthase subunit C 141
ADC-like P-loop containing nucleoside triphosphate hydrolases 142
FYVE/PHD zinc finger SET domain 146
FKBP-like FKBP-like 141
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 148
EF-hand PLC-like phosphodiesterases 143
P-loop containing nucleoside triphosphate hydrolases dsRNA-binding domain-like 145
Sec7 domain ARM repeat 147
Nucleotidyltransferase PAP/Archaeal CCA-adding enzyme, C-terminal domain 142
Helical domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 145
Translation proteins Ribosomal protein S5 domain 2-like 148
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 143
Homeodomain-like "Winged helix" DNA-binding domain 141
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 141
PLC-like phosphodiesterases C2 domain (Calcium/lipid-binding domain, CaLB) 143
RmlC-like cupins RmlC-like cupins 143
Retrovirus zinc finger-like domains Ribonuclease H-like 1411
RING/U-box WD40 repeat-like 148
TPR-like Thioredoxin-like 136
(Trans)glycosidases Ricin B-like lectins 133
cAMP-binding domain-like Ankyrin repeat 133
Galactose oxidase, central domain E set domains 132
HIT/MYND zinc finger-like Cysteine proteinases 131
Galactose mutarotase-like (Trans)glycosidases 134
Trypsin-like serine proteases PDZ domain-like 134
PAH2 domain PAH2 domain 133
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 135
E set domains (Trans)glycosidases 135
Periplasmic binding protein-like II ACT-like 131
POZ domain Skp1 dimerisation domain-like 132
N-terminal, heterodimerisation domain of RBP7 (RpoE) Nucleic acid-binding proteins 131
PH domain-like Oxysterol-binding protein-like 132
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 136
Ankyrin repeat P-loop containing nucleoside triphosphate hydrolases 135
Voltage-gated potassium channels Ankyrin repeat 133
EF-hand Mitochondrial carrier 132
RNase III domain-like RNase III domain-like 136
SET domain RuBisCo LSMT C-terminal, substrate-binding domain 132
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 131
Clc chloride channel CBS-domain pair 133
RNA-binding domain, RBD DNase I-like 1311
RCC1/BLIP-II Protein kinase-like (PK-like) 135
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 126
FYVE/PHD zinc finger P-loop containing nucleoside triphosphate hydrolases 127
CheY-like CheY-like 124
FYVE/PHD zinc finger RING/U-box 127
vWA-like C-terminal, gelsolin-like domain of Sec23/24 124
Actin depolymerizing proteins VHP, Villin headpiece domain 122
Protein kinase-like (PK-like) Protein kinase-like (PK-like) 129
Ribonuclease H-like Chromo domain-like 128
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 125
ARM repeat WD40 repeat-like 125
BAR/IMD domain-like SH3-domain 121
P-loop containing nucleoside triphosphate hydrolases E set domains 123
DNA/RNA polymerases Chromo domain-like 128
Zn-finger domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 124
ARM repeat Tudor/PWWP/MBT 122
beta-sandwich domain of Sec23/24 C-terminal, gelsolin-like domain of Sec23/24 124
Creatinase/aminopeptidase "Winged helix" DNA-binding domain 123
GST C-terminal domain-like eEF-1beta-like 123
Enolase N-terminal domain-like Enolase C-terminal domain-like 112
UROD/MetE-like UROD/MetE-like 112
EGF/Laminin Protein kinase-like (PK-like) 115
Ankyrin repeat Ankyrin repeat 113
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 114
Ubiquitin-like Homeodomain-like 111
Saposin Saposin 113
BRCT domain BRCT domain 117
Starch-binding domain-like Galactose-binding domain-like 112
Kelch motif Kelch motif 115
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 114
E set domains Glycosyl hydrolase domain 114
RNase III domain-like dsRNA-binding domain-like 115
RING/U-box Cysteine proteinases 117
Toll/Interleukin receptor TIR domain Toll/Interleukin receptor TIR domain 115
PAZ domain RNase III domain-like 115
GAF domain-like CheY-like 112
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 114
Glycoside hydrolase/deacetylase Galactose mutarotase-like 114
ACT-like Protein kinase-like (PK-like) 112
DUSP-like Cysteine proteinases 114
HCP-like TPR-like 108
CRAL/TRIO domain Supernatant protein factor (SPF), C-terminal domain 103
Galactose mutarotase-like Galactose-binding domain-like 103
Peptidase/esterase 'gauge' domain alpha/beta-Hydrolases 102
FF domain FF domain 107
P-loop containing nucleoside triphosphate hydrolases PRTase-like 101
RNA-binding domain, RBD DNA/RNA polymerases 108
Transcription factor IIA (TFIIA), alpha-helical domain Transcription factor IIA (TFIIA), beta-barrel domain 102
DPP6 N-terminal domain-like alpha/beta-Hydrolases 102
Translation proteins ThrRS/AlaRS common domain 102
TPR-like Chaperone J-domain 105
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 107
ARM repeat Subdomain of clathrin and coatomer appendage domain 103
CBS-domain pair CAD & PB1 domains 104
P-loop containing nucleoside triphosphate hydrolases Homeodomain-like 106
PYP-like sensor domain (PAS domain) Protein kinase-like (PK-like) 102
Chromo domain-like P-loop containing nucleoside triphosphate hydrolases 106
TATA-box binding protein-like TATA-box binding protein-like 101
DNA/RNA polymerases DNA/RNA polymerases 108
E set domains AMPKBI-like 102
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Adenine nucleotide alpha hydrolases-like 103
Chromo domain-like Chromo domain-like 106
Translation initiation factor 2 beta, aIF2beta, N-terminal domain Zinc-binding domain of translation initiation factor 2 beta 102
POZ domain TPR-like 103
ClpP/crotonase ClpP/crotonase 104
WD40 repeat-like Quinoprotein alcohol dehydrogenase-like 108
Galactose mutarotase-like Glycosyl hydrolase domain 101
Translational machinery components L30e-like 103
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 103
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 103
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 104
Clathrin adaptor appendage domain Subdomain of clathrin and coatomer appendage domain 103
P-loop containing nucleoside triphosphate hydrolases ARM repeat 105
FAD/NAD(P)-binding domain EF-hand 103
CRAL/TRIO N-terminal domain Supernatant protein factor (SPF), C-terminal domain 103
PLP-dependent transferases PLP-dependent transferases 104
RCC1/BLIP-II RCC1/BLIP-II 103
ENT-like Tudor/PWWP/MBT 103
PAZ domain dsRNA-binding domain-like 104
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 105
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 92
Flavoproteins Riboflavin synthase domain-like 94
Oxidoreductase molybdopterin-binding domain E set domains 92
Voltage-gated potassium channels Voltage-gated potassium channels 93
Clathrin heavy-chain terminal domain ARM repeat 91
Actin-crosslinking proteins (Trans)glycosidases 91
PH domain-like ArfGap/RecO-like zinc finger 94
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 95
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 93
Ubiquitin-like Zn-binding ribosomal proteins 91
C2 domain (Calcium/lipid-binding domain, CaLB) Formin homology 2 domain (FH2 domain) 92
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 93
PLP-binding barrel Alanine racemase C-terminal domain-like 92
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 98
FYVE/PHD zinc finger Homeodomain-like 94
BAR/IMD domain-like PH domain-like 94
alpha-D-mannose-specific plant lectins alpha-D-mannose-specific plant lectins 92
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 93
Cytochrome c Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 91
P-loop containing nucleoside triphosphate hydrolases RNase III domain-like 94
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 93
POZ domain Ankyrin repeat 94
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 93
P-loop containing nucleoside triphosphate hydrolases PH domain-like 93
Ribosomal protein L6 Ribosomal protein L6 92
Chaperone J-domain 4Fe-4S ferredoxins 93
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 92
P-loop containing nucleoside triphosphate hydrolases PAZ domain 94
Aldolase NAD(P)-binding Rossmann-fold domains 94
GroEL apical domain-like SAICAR synthase-like 92
BAR/IMD domain-like ArfGap/RecO-like zinc finger 94
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 92
Ubiquitin-like Protein kinase-like (PK-like) 92
Cysteine proteinases Ubiquitin-like 95
CCCH zinc finger Eukaryotic type KH-domain (KH-domain type I) 92
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 91
ACT-like NAD(P)-binding Rossmann-fold domains 94
DNase I-like DNase I-like 94
PreATP-grasp domain Rudiment single hybrid motif 95
F-box domain HCP-like 93
HAD-like dsRNA-binding domain-like 93
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 92
Flavoproteins Ferredoxin reductase-like, C-terminal NADP-linked domain 94
HAD-like NTF2-like 81
P-loop containing nucleoside triphosphate hydrolases Retrovirus zinc finger-like domains 85
SBT domain Ankyrin repeat 82
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 84
(Phosphotyrosine protein) phosphatases II C2 domain (Calcium/lipid-binding domain, CaLB) 82
PriA/YqbF domain GINS helical bundle-like 82
GAF domain-like GAF domain-like 82
(Phosphotyrosine protein) phosphatases II DNA ligase/mRNA capping enzyme, catalytic domain 82
GST C-terminal domain-like eEF1-gamma domain 82
Folate-binding domain Aminomethyltransferase beta-barrel domain 82
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 84
Translation initiation factor 2 beta, aIF2beta, N-terminal domain ARM repeat 81
SNARE fusion complex SNARE fusion complex 81
(Phosphotyrosine protein) phosphatases II Nucleic acid-binding proteins 82
PH domain-like Ankyrin repeat 83
ArfGap/RecO-like zinc finger Ankyrin repeat 83
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 82
ARM repeat TPR-like 81
Nucleotidyltransferase Poly A polymerase C-terminal region-like 83
Galactose-binding domain-like NAD(P)-binding Rossmann-fold domains 83
TPR-like CAD & PB1 domains 84
PYP-like sensor domain (PAS domain) GAF domain-like 82
PLC-like phosphodiesterases PLC-like phosphodiesterases 81
ARM repeat C2 domain (Calcium/lipid-binding domain, CaLB) 87
ArfGap/RecO-like zinc finger C2 domain (Calcium/lipid-binding domain, CaLB) 83
Tudor/PWWP/MBT FYVE/PHD zinc finger 83
YrdC/RibB RibA-like 83
Tudor/PWWP/MBT SET domain 83
CCCH zinc finger RING/U-box 82
Aconitase iron-sulfur domain LeuD/IlvD-like 82
ARM repeat POZ domain 83
NAD-binding domain of HMG-CoA reductase Substrate-binding domain of HMG-CoA reductase 81
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 84
Thioredoxin-like ERP29 C domain-like 82
BAR/IMD domain-like Ankyrin repeat 83
Galactose mutarotase-like Starch-binding domain-like 81
Zinc-binding domain of translation initiation factor 2 beta ARM repeat 81
SWIB/MDM2 domain Plus3-like 87
Staphylococcal nuclease Tudor/PWWP/MBT 73
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 73
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 71
Voltage-gated potassium channels EF-hand 73
P-loop containing nucleoside triphosphate hydrolases Bromodomain 72
CoA-dependent acyltransferases CoA-dependent acyltransferases 72
ARM repeat UBA-like 74
E set domains CBS-domain pair 72
DNase I-like EF-hand 73
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 72
C2 domain (Calcium/lipid-binding domain, CaLB) vWA-like 72
WW domain WW domain 75
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 74
Amidase signature (AS) enzymes TPR-like 71
Thioredoxin-like eEF1-gamma domain 71
Protease propeptides/inhibitors PA domain 71
(Trans)glycosidases (Trans)glycosidases 74
DUSP-like Ubiquitin-like 73
Cyclophilin-like TPR-like 71
HCP-like HIT/MYND zinc finger-like 72
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 73
PX domain BAR/IMD domain-like 72
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 72
Staphylococcal nuclease Staphylococcal nuclease 73
P-loop containing nucleoside triphosphate hydrolases TGS-like 72
Activator of Hsp90 ATPase, Aha1 Bet v1-like 71
Carbamate kinase-like ALDH-like 71
cAMP-binding domain-like Thioesterase/thiol ester dehydrase-isomerase 73
(Phosphotyrosine protein) phosphatases II Formin homology 2 domain (FH2 domain) 71
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 72
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 72
Cysteine proteinases UBA-like 72
UBA-like Hect, E3 ligase catalytic domain 74
RNA-binding domain, RBD Ran binding protein zinc finger-like 73
AN1-like Zinc finger AN1-like Zinc finger 73
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 72
DEK C-terminal domain SWIB/MDM2 domain 72
F-box domain HIT/MYND zinc finger-like 72
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 72
RING/U-box PUA domain-like 74
UBC-like UBA-like 71
alpha-ketoacid dehydrogenase kinase, N-terminal domain ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 72
Acyl-CoA dehydrogenase C-terminal domain-like Acyl-CoA dehydrogenase C-terminal domain-like 72
Translation proteins Initiation factor IF2/eIF5b, domain 3 72
PDZ domain-like ClpP/crotonase 71
Aldolase Aminoacid dehydrogenase-like, N-terminal domain 72
Carbamate kinase-like ACT-like 73
WW domain FF domain 75
GroEL-intermediate domain like GroEL-intermediate domain like 63
PRTase-like PRTase-like 62
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 62
HD-domain/PDEase-like Nucleotidyltransferase 65
NAD(P)-binding Rossmann-fold domains Citrate synthase 62
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 66
RING/U-box Homeodomain-like 63
Class II aaRS and biotin synthetases C-terminal domain of ProRS 62
Plant lectins/antimicrobial peptides Lysozyme-like 61
POZ domain POZ domain 64
SWIB/MDM2 domain SWIB/MDM2 domain 61
Clavaminate synthase-like beta-beta-alpha zinc fingers 62
NAD(P)-binding Rossmann-fold domains Glutamyl tRNA-reductase dimerization domain 61
USP8 N-terminal domain-like JAB1/MPN domain 62
Homeodomain-like FAD-linked reductases, C-terminal domain 63
Actin depolymerizing proteins C-terminal, gelsolin-like domain of Sec23/24 64
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 62
Activating enzymes of the ubiquitin-like proteins Activating enzymes of the ubiquitin-like proteins 63
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 65
Surp module (SWAP domain) Surp module (SWAP domain) 62
RNA-binding domain, RBD RING/U-box 62
Nucleotidylyl transferase Ribosomal protein L25-like 62
PLP-dependent transferases Leucine zipper domain 61
Protein kinase-like (PK-like) KA1-like 62
Thioredoxin-like Cysteine-rich domain 62
YjeF N-terminal domain-like FMN-binding split barrel 61
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 61
Domain of poly(ADP-ribose) polymerase ADP-ribosylation 64
PH domain-like GTPase activation domain, GAP 61
TPR-like HSP20-like chaperones 61
PYP-like sensor domain (PAS domain) F-box domain 62
Class II aaRS ABD-related C-terminal domain of ProRS 62
Homeodomain-like FAD/NAD(P)-binding domain 63
beta-Galactosidase/glucuronidase domain beta-Galactosidase/glucuronidase domain 64
TRAF domain-like TRAF domain-like 62
Bactericidal permeability-increasing protein, BPI Bactericidal permeability-increasing protein, BPI 61
BRCT domain RING/U-box 63
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 62
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Translational machinery components 61
Glutamyl tRNA-reductase catalytic, N-terminal domain Glutamyl tRNA-reductase dimerization domain 61
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 61
Taf5 N-terminal domain-like WD40 repeat-like 62
PUA domain-like Nucleotidylyl transferase 62
Dimeric alpha+beta barrel Dimeric alpha+beta barrel 61
Ribonuclease H-like Eukaryotic type KH-domain (KH-domain type I) 61
P-loop containing nucleoside triphosphate hydrolases Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 63
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 62
Zinc beta-ribbon Cyclin-like 63
WGR domain-like Domain of poly(ADP-ribose) polymerase 64
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 63
Kelch motif Metallo-dependent phosphatases 62
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 61
DPP6 N-terminal domain-like WD40 repeat-like 63
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 61
Dihydrofolate reductase-like Thymidylate synthase/dCMP hydroxymethylase 62
Heat shock protein 70kD (HSP70), C-terminal subdomain Heat shock protein 70kD (HSP70), C-terminal subdomain 62
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 64
(Trans)glycosidases Chitinase insertion domain 61
(Phosphotyrosine protein) phosphatases II Actin depolymerizing proteins 63
ARID-like HSP20-like chaperones 61
WGR domain-like ADP-ribosylation 64
PEP carboxykinase N-terminal domain PEP carboxykinase-like 62
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 61
Calponin-homology domain, CH-domain EB1 dimerisation domain-like 62
Acid proteases Chromo domain-like 64
Class I glutamine amidotransferase-like Class I glutamine amidotransferase-like 61
HAD-like Glycerol-3-phosphate (1)-acyltransferase 61
P-loop containing nucleoside triphosphate hydrolases Tropomyosin 65
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 L30e-like 61
DNA-binding domain DNA-binding pseudobarrel domain 55
Galactose-binding domain-like Glycosyl hydrolase domain 52
Plus3-like GYF domain 54
FMN-linked oxidoreductases alpha-helical ferredoxin 52
SWIB/MDM2 domain GYF domain 54
Thioredoxin-like "Winged helix" DNA-binding domain 51
MIT domain P-loop containing nucleoside triphosphate hydrolases 51
AraD/HMP-PK domain-like HAD-like 51
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 51
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 51
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 52
HAND domain of the nucleosome remodeling ATPase ISWI Homeodomain-like 52
TRAF domain-like Cysteine proteinases 53
FAD-binding/transporter-associated domain-like Molybdenum cofactor-binding domain 51
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 51
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 53
(Phosphotyrosine protein) phosphatases II E set domains 53
Cysteine proteinases Granulin repeat 52
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 55
2Fe-2S ferredoxin-like Molybdenum cofactor-binding domain 51
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 51
FYVE/PHD zinc finger GYF domain 54
ARID-like HMG-box 53
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 51
ARID-like FYVE/PHD zinc finger 52
Quinoprotein alcohol dehydrogenase-like YVTN repeat-like/Quinoprotein amine dehydrogenase 55
PA domain Zn-dependent exopeptidases 52
PUG domain-like Ubiquitin-like 53
FYVE/PHD zinc finger SWIB/MDM2 domain 55
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 51
Alpha subunit of glutamate synthase, C-terminal domain FAD/NAD(P)-binding domain 52
Macro domain-like CRAL/TRIO domain 51
TPR-like RING/U-box 53
Clavaminate synthase-like Clavaminate synthase-like 52
Nucleoside hydrolase Nucleoside hydrolase 54
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 51
Cysteine-rich domain Cysteine-rich domain 54
CO dehydrogenase flavoprotein C-terminal domain-like CO dehydrogenase molybdoprotein N-domain-like 51
Hypothetical protein c14orf129, hspc210 TPR-like 52
2Fe-2S ferredoxin-like CO dehydrogenase molybdoprotein N-domain-like 51
P-loop containing nucleoside triphosphate hydrolases CYTH-like phosphatases 52
FYVE/PHD zinc finger Transducin (alpha subunit), insertion domain 51
SET domain TPR-like 52
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 52
Rap30/74 interaction domains "Winged helix" DNA-binding domain 52
P-loop containing nucleoside triphosphate hydrolases Phosphoglycerate mutase-like 52
F-box domain WD40 repeat-like 53
P-loop containing nucleoside triphosphate hydrolases HAND domain of the nucleosome remodeling ATPase ISWI 52
PIN domain-like Nucleic acid-binding proteins 52
Alpha subunit of glutamate synthase, C-terminal domain alpha-helical ferredoxin 52
Ricin B-like lectins Glycosyl hydrolase domain 51
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 52
Cysteine-rich domain NAD kinase/diacylglycerol kinase-like 52
Serine metabolism enzymes domain ACT-like 51
PreATP-grasp domain PreATP-grasp domain 52
Galactose oxidase, central domain P-loop containing nucleoside triphosphate hydrolases 51
CO dehydrogenase flavoprotein C-terminal domain-like Molybdenum cofactor-binding domain 51
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 55
(Phosphotyrosine protein) phosphatases II (Phosphotyrosine protein) phosphatases II 52
FYVE/PHD zinc finger Plus3-like 55
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FAD/NAD(P)-binding domain 52
alpha-helical ferredoxin FAD/NAD(P)-binding domain 52
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 51
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 51
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 53
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 53
CO dehydrogenase ISP C-domain like Molybdenum cofactor-binding domain 51
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 53
FAD-binding/transporter-associated domain-like CO dehydrogenase molybdoprotein N-domain-like 51
UDP-Glycosyltransferase/glycogen phosphorylase UDP-Glycosyltransferase/glycogen phosphorylase 51
N-terminal nucleophile aminohydrolases (Ntn hydrolases) alpha-helical ferredoxin 52
Translation proteins Translation proteins 51
Fe-S cluster assembly (FSCA) domain-like Fe-S cluster assembly (FSCA) domain-like 52
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 51
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 52
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 52
P-loop containing nucleoside triphosphate hydrolases Sec63 N-terminal domain-like 54
Adenine nucleotide alpha hydrolases-like RING/U-box 51
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 55
LysM domain Protein kinase-like (PK-like) 51
CO dehydrogenase ISP C-domain like CO dehydrogenase molybdoprotein N-domain-like 51
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 53
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 52
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 55
RNA-binding domain, RBD WW domain 51
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 53
Carbamate kinase-like Acyl-CoA N-acyltransferases (Nat) 52
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 51
Starch-binding domain-like P-loop containing nucleoside triphosphate hydrolases 52
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 52
Sec63 N-terminal domain-like E set domains 53
HAD-like BRCT domain 52
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 52
FMN-linked oxidoreductases FAD/NAD(P)-binding domain 52
Acyl-CoA binding protein Kelch motif 41
PH domain-like WD40 repeat-like 42
Macro domain-like Zn-dependent exopeptidases 42
Starch-binding domain-like Phosphoglycerate mutase-like 41
Urease, gamma-subunit Urease, beta-subunit 42
Ribonuclease H-like RING/U-box 43
SMAD/FHA domain P-loop containing nucleoside triphosphate hydrolases 42
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 41
PUA domain-like Ribosomal protein S5 domain 2-like 42
E set domains Ferredoxin reductase-like, C-terminal NADP-linked domain 41
TAZ domain RING/U-box 42
CCCH zinc finger Ribonuclease H-like 41
PurM N-terminal domain-like PurM C-terminal domain-like 43
WD40 repeat-like 3-carboxy-cis,cis-mucoante lactonizing enzyme 42
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 41
Urease, beta-subunit Composite domain of metallo-dependent hydrolases 42
Hairpin loop containing domain-like Protein kinase-like (PK-like) 42
alpha-D-mannose-specific plant lectins Hairpin loop containing domain-like 42
Ribonuclease H-like Nucleic acid-binding proteins 42
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 41
E set domains Riboflavin synthase domain-like 41
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 41
Cysteine proteinases Calpain large subunit, middle domain (domain III) 41
PYP-like sensor domain (PAS domain) Kelch motif 41
P-loop containing nucleoside triphosphate hydrolases Protein kinase-like (PK-like) 44
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 42
Metalloproteases ("zincins"), catalytic domain ARM repeat 43
BRCT domain WGR domain-like 42
Cytochrome b5-like heme/steroid binding domain Riboflavin synthase domain-like 41
WD40 repeat-like DNase I-like 42
HMG-box HMG-box 43
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 42
FYVE/PHD zinc finger GroEL apical domain-like 41
Oxidoreductase molybdopterin-binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 41
Formate/glycerate dehydrogenase catalytic domain-like Formate/glycerate dehydrogenase catalytic domain-like 42
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 42
RNA-binding domain, RBD DPP6 N-terminal domain-like 43
Probable bacterial effector-binding domain Probable bacterial effector-binding domain 42
BRCT domain ADP-ribosylation 42
BSD domain-like BSD domain-like 42
Retrovirus zinc finger-like domains RING/U-box 41
Tudor/PWWP/MBT RNA-binding domain, RBD 42
P-loop containing nucleoside triphosphate hydrolases D-aminoacid aminotransferase-like PLP-dependent enzymes 41
FYVE/PHD zinc finger SAICAR synthase-like 41
Chromo domain-like S-adenosyl-L-methionine-dependent methyltransferases 42
Aspartate/glutamate racemase Aspartate/glutamate racemase 42
Surp module (SWAP domain) Ubiquitin-like 41
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 41
PH domain-like BEACH domain 42
PA domain Transferrin receptor-like dimerisation domain 41
Urease, beta-subunit Metallo-dependent hydrolases 42
DNA clamp DNA clamp 41
Retrovirus zinc finger-like domains Acid proteases 42
BRCT domain Domain of poly(ADP-ribose) polymerase 42
Second domain of FERM PH domain-like 42
Putative DNA-binding domain Class II aaRS and biotin synthetases 42
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 41
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 41
beta-sandwich domain of Sec23/24 RING/U-box 42
Cytochrome P450 Cytochrome P450 41
PRTase-like Ribulose-phoshate binding barrel 41
Nucleotidylyl transferase Nucleotidylyl transferase 41
TAZ domain FYVE/PHD zinc finger 42
Eukaryotic RPB5 N-terminal domain RPB5-like RNA polymerase subunit 41
Class II aaRS and biotin synthetases Translation proteins 41
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 41
WD40 repeat-like TPR-like 42
E set domains Cytochrome b5-like heme/steroid binding domain 41
WW domain P-loop containing nucleoside triphosphate hydrolases 41
Second domain of FERM P-loop containing nucleoside triphosphate hydrolases 42
NSFL1 (p97 ATPase) cofactor p47, SEP domain Ubiquitin-like 42
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 41
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 42
Ribonuclease H-like HRDC-like 43
P-loop containing nucleoside triphosphate hydrolases vWA-like 43
LysM domain LysM domain 41
PreATP-grasp domain Methylglyoxal synthase-like 42
Carbamoyl phosphate synthetase, large subunit connection domain Methylglyoxal synthase-like 42
ACT-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 43
ARM repeat "Winged helix" DNA-binding domain 41
Concanavalin A-like lectins/glucanases Cysteine proteinases 41
Nucleic acid-binding proteins Eukaryotic type KH-domain (KH-domain type I) 43
Cytochrome b5-like heme/steroid binding domain Ferredoxin reductase-like, C-terminal NADP-linked domain 41
Domain of the SRP/SRP receptor G-proteins Signal peptide-binding domain 41
tRNA-binding arm Class II aaRS and biotin synthetases 42
PapD-like Ankyrin repeat 42
Concanavalin A-like lectins/glucanases Calpain large subunit, middle domain (domain III) 41
Oxidoreductase molybdopterin-binding domain Riboflavin synthase domain-like 41
Carbamoyl phosphate synthetase, large subunit connection domain PreATP-grasp domain 42
Oxidoreductase molybdopterin-binding domain Cytochrome b5-like heme/steroid binding domain 41
Thioredoxin-like Ubiquitin-like 42
Carbamate kinase-like Carbamate kinase-like 41
F-box domain Clavaminate synthase-like 43
Urease, gamma-subunit Composite domain of metallo-dependent hydrolases 42
Leukotriene A4 hydrolase N-terminal domain ARM repeat 43
Alpha-L RNA-binding motif Pseudouridine synthase 42
Glutathione synthetase ATP-binding domain-like Single hybrid motif 42
UraD-Like Transthyretin (synonym: prealbumin) 41
PreATP-grasp domain Single hybrid motif 42
HLH, helix-loop-helix DNA-binding domain ACT-like 43
Chelatase Chlorophyll a-b binding protein 42
LEA14-like LEA14-like 41
Glutathione synthetase ATP-binding domain-like Methylglyoxal synthase-like 42
Zn-dependent exopeptidases Transferrin receptor-like dimerisation domain 41
WD40 repeat-like Bromodomain 41
BEACH domain WD40 repeat-like 42
Urease, gamma-subunit Metallo-dependent hydrolases 42
Carbamoyl phosphate synthetase, large subunit connection domain Glutathione synthetase ATP-binding domain-like 42
Toll/Interleukin receptor TIR domain RNI-like 44
Rudiment single hybrid motif Single hybrid motif 42
BRCT domain P-loop containing nucleoside triphosphate hydrolases 31
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 32
Dom34/Pelota N-terminal domain-like Translational machinery components 31
Second domain of FERM Prismane protein-like 31
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 31
Mannose-binding lectins Mannose-binding lectins 31
Actin-crosslinking proteins Actin-crosslinking proteins 31
RNA-binding domain, RBD ENTH/VHS domain 31
POZ domain TAZ domain 32
Nucleic acid-binding proteins "Winged helix" DNA-binding domain 32
SNARE-like P-loop containing nucleoside triphosphate hydrolases 31
Homeodomain-like Bromodomain 31
Clavaminate synthase-like FYVE/PHD zinc finger 33
S15/NS1 RNA-binding domain Class II aaRS and biotin synthetases 32
alpha/beta-Hydrolases alpha/beta-Hydrolases 33
Glutathione synthetase ATP-binding domain-like Phosphoglycerate mutase-like 32
WD40 repeat-like YVTN repeat-like/Quinoprotein amine dehydrogenase 33
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 31
FKBP-like Triger factor/SurA peptide-binding domain-like 31
Six-hairpin glycosidases AbfB domain 32
P-loop containing nucleoside triphosphate hydrolases Microbial and mitochondrial ADK, insert "zinc finger" domain 31
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 31
Trigger factor ribosome-binding domain FKBP-like 31
Ribonuclease H-like SH2 domain 31
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 31
vWA-like SPOC domain-like 32
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 31
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 31
FYSH domain Hypothetical protein AF0491, middle domain 31
Fumarylacetoacetate hydrolase, FAH, N-terminal domain FAH 31
RuvA domain 2-like Nucleic acid-binding proteins 31
Trypsin-like serine proteases Trypsin-like serine proteases 32
Ribosomal L27 protein-like Eukaryotic type KH-domain (KH-domain type I) 32
Thioredoxin-like Six-hairpin glycosidases 33
(Phosphotyrosine protein) phosphatases II NAD kinase/diacylglycerol kinase-like 31
ACT-like Formyltransferase 31
Carbamate kinase-like NAD(P)-binding Rossmann-fold domains 32
Lipocalins Lipocalins 32
Protein kinase-like (PK-like) Formin homology 2 domain (FH2 domain) 32
Cystatin/monellin Cystatin/monellin 31
Thioredoxin-like FAD-dependent thiol oxidase 31
Rhomboid-like UBA-like 31
PP2C-like cAMP-binding domain-like 32
Quinoprotein alcohol dehydrogenase-like 3-carboxy-cis,cis-mucoante lactonizing enzyme 31
Galactose oxidase, central domain Galactose oxidase, central domain 31
UBA-like KA1-like 31
Tropomyosin Tropomyosin 32
Phosphoglycerate mutase-like Phosphoglycerate mutase-like 32
ISP transmembrane anchor ISP domain 31
Zinc beta-ribbon Zinc beta-ribbon 31
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase C-terminal domain-like 31
Chaperone J-domain Thioredoxin-like 32
FYSH domain beta-beta-alpha zinc fingers 31
Chaperone J-domain E set domains 32
Tex N-terminal region-like SH2 domain 31
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 32
Flavoproteins Radical SAM enzymes 32
F-box domain SMI1/KNR4-like 31
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 32
Zn-dependent exopeptidases Carboxypeptidase regulatory domain-like 32
Ribonuclease H-like RuvA domain 2-like 31
DAK1/DegV-like DhaL-like 31
Cytidine deaminase-like Dihydrofolate reductase-like 32
SMI1/KNR4-like ApaG-like 31
TPR-like EF-hand 33
E set domains RNA-binding domain, RBD 31
ATP-dependent DNA ligase DNA-binding domain Nucleic acid-binding proteins 32
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 32
Restriction endonuclease-like RuvA domain 2-like 32
TPR-like "Winged helix" DNA-binding domain 31
ThrRS/AlaRS common domain Class II aaRS ABD-related 32
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 31
F-box domain P-loop containing nucleoside triphosphate hydrolases 31
TAZ domain TAZ domain 31
RNA-binding domain, RBD Surp module (SWAP domain) 31
Putative DNA-binding domain PheT/TilS domain 31
Ankyrin repeat TPR-like 31
SPOC domain-like C-terminal domain of Ku80 32
C-terminal, gelsolin-like domain of Sec23/24 VHP, Villin headpiece domain 31
PH domain-like Phospholipase D/nuclease 31
Chaperone J-domain Sec63 N-terminal domain-like 32
Tex N-terminal region-like RuvA domain 2-like 31
FYVE/PHD zinc finger Chromo domain-like 33
Tex N-terminal region-like Ribonuclease H-like 31
Outer arm dynein light chain 1 RNI-like 33
Calcium ATPase, transmembrane domain M Calcium ATPase, transmembrane domain M 32
Formiminotransferase domain of formiminotransferase-cyclodeaminase. Formiminotransferase domain of formiminotransferase-cyclodeaminase. 31
PH domain-like ARM repeat 31
RuvA domain 2-like SH2 domain 31
SNARE-like Domain of the SRP/SRP receptor G-proteins 31
Histone-fold ARM repeat 32
P-loop containing nucleoside triphosphate hydrolases RNA-binding domain, RBD 32
PH domain-like HMG-box 31
Chromo domain-like Homeodomain-like 33
PH domain-like Bet v1-like 31
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment DNA breaking-rejoining enzymes 31
BRCT domain post-AAA+ oligomerization domain-like 31
Protein kinase-like (PK-like) (Phosphotyrosine protein) phosphatases II 32
Ribosomal L27 protein-like Nucleic acid-binding proteins 32
RuvA domain 2-like RuvA domain 2-like 31
Tex N-terminal region-like Nucleic acid-binding proteins 31
F-box domain ApaG-like 31
Protein kinase-like (PK-like) UBA-like 31
PheT/TilS domain Class II aaRS and biotin synthetases 31
Dcp2 domain-like Nudix 32
FYVE/PHD zinc finger PUA domain-like 31
Arp2/3 complex subunits Arp2/3 complex subunits 31
HIT/MYND zinc finger-like Creatinase/aminopeptidase 31
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 32
Chaperone J-domain RNA-binding domain, RBD 31
UBA-like NSFL1 (p97 ATPase) cofactor p47, SEP domain 32
L domain-like Ubiquitin-like 33
F-box domain Actin-like ATPase domain 31
FKBP-like Rhodanese/Cell cycle control phosphatase 31
Cna protein B-type domain Cna protein B-type domain 32
Putative DNA-binding domain Putative DNA-binding domain 31
WD40 repeat-like Cyclophilin-like 33
Rad51 N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 31
Protein kinase-like (PK-like) Acyl-CoA dehydrogenase NM domain-like 31
Hypothetical protein AF0491, middle domain beta-beta-alpha zinc fingers 31
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 31
Glutamine synthetase/guanido kinase GatB/YqeY motif 31
Dom34/Pelota N-terminal domain-like L30e-like 31
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 31
RING/U-box Ran binding protein zinc finger-like 31
beta-beta-alpha zinc fingers Ankyrin repeat 32
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 31
Outer arm dynein light chain 1 L domain-like 33
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 31
PH domain-like Prismane protein-like 31
RING/U-box UBA-like 32
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 31
Cytidine deaminase-like Cytidine deaminase-like 31
Surp module (SWAP domain) ENTH/VHS domain 31
E set domains E set domains 33
Protein prenylyltransferase L domain-like 31
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 32
"Winged helix" DNA-binding domain Sec63 N-terminal domain-like 32
Smc hinge domain Smc hinge domain 33
Carbamate kinase-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 32
Cna protein B-type domain Starch-binding domain-like 32
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 31
P-loop containing nucleoside triphosphate hydrolases Prismane protein-like 31
Actin-like ATPase domain AF1104-like 32
Nucleic acid-binding proteins SH2 domain 31
Adenine nucleotide alpha hydrolases-like Thioredoxin-like 31
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 31
TPR-like RNA-binding domain, RBD 31
ARM repeat Chaperone J-domain 32
alpha/beta knot Nucleic acid-binding proteins 32
ATP-dependent DNA ligase DNA-binding domain DNA ligase/mRNA capping enzyme, catalytic domain 32
"Winged helix" DNA-binding domain Zinc beta-ribbon 31
SMAD/FHA domain Phospholipase D/nuclease 33
Metallo-dependent phosphatases Metallo-dependent phosphatases 33
DNA-glycosylase Nudix 21
Ribonuclease PH domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 22
Subtilisin-like Subtilisin-like 22
Endosomal sorting complex assembly domain VPS28 C-terminal domain-like 21
PRC-barrel domain Nucleotide-diphospho-sugar transferases 21
P-loop containing nucleoside triphosphate hydrolases HRDC-like 22
PUA domain-like alpha/beta knot 21
ABC transporter transmembrane region Retrovirus zinc finger-like domains 22
CBS-domain pair FAD-binding/transporter-associated domain-like 21
cAMP-binding domain-like Protein kinase-like (PK-like) 21
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 21
Nucleic acid-binding proteins eIF-2-alpha, C-terminal domain 21
P-loop containing nucleoside triphosphate hydrolases Ribonuclease H-like 22
beta-beta-alpha zinc fingers S-adenosyl-L-methionine-dependent methyltransferases 21
beta-Galactosidase/glucuronidase domain Galactose mutarotase-like 22
SAP domain FYVE/PHD zinc finger 21
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Zinc beta-ribbon 22
PDZ domain-like PDZ domain-like 21
TGS-like ACT-like 22
TGS-like ThrRS/AlaRS common domain 21
Acyl-CoA N-acyltransferases (Nat) Bromodomain 21
DEK C-terminal domain ssDNA-binding transcriptional regulator domain 21
BRCT domain PsbU/PolX domain-like 21
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleotidylyl transferase 22
PsbU/PolX domain-like Nucleotidyltransferase 21
SMAD/FHA domain BRCT domain 21
PurM C-terminal domain-like Class I glutamine amidotransferase-like 22
GYF domain CCCH zinc finger 22
Cyclophilin-like RNA-binding domain, RBD 21
Protein kinase-like (PK-like) NTF2-like 21
HD-domain/PDEase-like TGS-like 22
Translation proteins Nucleotide-diphospho-sugar transferases 21
Sec63 N-terminal domain-like Sec63 N-terminal domain-like 21
N-terminal domain of adenylylcyclase associated protein, CAP C-terminal domain of adenylylcyclase associated protein 21
Heat shock protein 70kD (HSP70), peptide-binding domain Ribonuclease H-like 22
Cap-Gly domain L domain-like 22
SIS domain SIS domain 22
Class I glutamine amidotransferase-like ADC synthase 21
Nucleic acid-binding proteins eIF2alpha middle domain-like 21
RING/U-box Leucine zipper domain 21
GST C-terminal domain-like Ribosomal protein L25-like 21
UDP-Glycosyltransferase/glycogen phosphorylase Ribosomal protein S5 domain 2-like 21
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 21
UBA-like PUG domain-like 21
Nucleic acid-binding proteins TPR-like 22
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Chaperone J-domain Chaperone J-domain 22
ARM repeat FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) 22
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Eukaryotic type KH-domain (KH-domain type I) 22
Kelch motif S-adenosyl-L-methionine-dependent methyltransferases 22
Class I glutamine amidotransferase-like Ribulose-phoshate binding barrel 22
FAD/NAD(P)-binding domain Thioredoxin-like 21
vWA-like Cysteine-rich domain 21
FAD/NAD(P)-binding domain SMAD/FHA domain 21
GYF domain RNA-binding domain, RBD 21
DNA/RNA polymerases Amine oxidase catalytic domain 21
Cryptochrome/photolyase, N-terminal domain alpha/beta-Hydrolases 21
SPOC domain-like SAP domain 22
PA domain RING/U-box 21
HisI-like all-alpha NTP pyrophosphatases 21
FAD/NAD(P)-binding domain Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 21
P-loop containing nucleoside triphosphate hydrolases RuvA domain 2-like 21
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 21
BRCT domain DNA polymerase beta, N-terminal domain-like 21
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 22
Ubiquitin-like HAD-like 21
Clavaminate synthase-like RING/U-box 22
PYP-like sensor domain (PAS domain) Galactose oxidase, central domain 21
P-loop containing nucleoside triphosphate hydrolases Macro domain-like 22
Glucocorticoid receptor-like (DNA-binding domain) WGR domain-like 21
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK Dihydropteroate synthetase-like 22
Pre-PUA domain PUA domain-like 21
Rudiment single hybrid motif ClpP/crotonase 21
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 22
alpha/beta-Hydrolases P-loop containing nucleoside triphosphate hydrolases 22
"Winged helix" DNA-binding domain RNI-like 22
Arabinanase/levansucrase/invertase Nucleotide-diphospho-sugar transferases 22
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
Protein kinase-like (PK-like) BEACH domain 22
DNA/RNA polymerases Protein kinase-like (PK-like) 22
UDP-Glycosyltransferase/glycogen phosphorylase GHMP Kinase, C-terminal domain 21
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 Elongation factor TFIIS domain 2 22
Dihydrofolate reductase-like YbiA-like 21
Glutathione synthetase ATP-binding domain-like N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 21
GST C-terminal domain-like Nucleic acid-binding proteins 21
Concanavalin A-like lectins/glucanases BEACH domain 21
AF0104/ALDC/Ptd012-like AF0104/ALDC/Ptd012-like 21
Quinoprotein alcohol dehydrogenase-like DPP6 N-terminal domain-like 22
Rhodanese/Cell cycle control phosphatase alpha/beta-Hydrolases 22
Ribosomal protein S5 domain 2-like Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 22
RNA-binding domain, RBD PWI domain 21
Formate/glycerate dehydrogenase catalytic domain-like Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 22
SWIB/MDM2 domain CCCH zinc finger 22
WD40 repeat-like Nucleoporin domain 22
Nucleic acid-binding proteins Elongation factor Ts (EF-Ts), dimerisation domain 21
Cysteine proteinases Protein kinase-like (PK-like) 21
Single hybrid motif Single hybrid motif 22
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 22
dsRNA-binding domain-like S-adenosyl-L-methionine-dependent methyltransferases 21
Elongation factor TFIIS domain 2 Zinc beta-ribbon 22
FYVE/PHD zinc finger Ankyrin repeat 21
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) Protein kinase-like (PK-like) 22
Acyl-CoA binding protein Ankyrin repeat 21
cAMP-binding domain-like cAMP-binding domain-like 21
F-box domain NTF2-like 22
SWIB/MDM2 domain eIF1-like 22
Ankyrin repeat S-adenosyl-L-methionine-dependent methyltransferases 21
Metallo-hydrolase/oxidoreductase Metallo-hydrolase/oxidoreductase 21
PDZ domain-like E set domains 22
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 22
Macro domain-like HIT-like 22
Nucleotidyltransferase ACT-like 22
SGNH hydrolase SGNH hydrolase 22
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 21
Chaperone J-domain HSC20 (HSCB), C-terminal oligomerisation domain 21
Nucleotide-binding domain Nucleotide-binding domain 21
EF-hand Calponin-homology domain, CH-domain 21
TPR-like RNI-like 22
C2 domain (Calcium/lipid-binding domain, CaLB) MHC antigen-recognition domain 22
Trimeric LpxA-like enzymes ARM repeat 21
Homeodomain-like Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 21
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 21
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 21
vWA-like C-terminal domain of Ku80 21
Tropomyosin Apolipoprotein A-I 21
PreATP-grasp domain ClpP/crotonase 21
P-loop containing nucleoside triphosphate hydrolases Clavaminate synthase-like 22
Toll/Interleukin receptor TIR domain EF-hand 21
Plant lectins/antimicrobial peptides Barwin-like endoglucanases 21
BRCT domain Nucleotidyltransferase 21
C-type lectin-like Protein kinase-like (PK-like) 22
RNI-like Cysteine proteinases 21
TAF(II)230 TBP-binding fragment Ubiquitin-like 22
Translation proteins SH3-like domain Translation proteins SH3-like domain 21
CarD-like TRCF domain-like 21
RNI-like WD40 repeat-like 21
GST C-terminal domain-like Nucleotidylyl transferase 21
SET domain SET domain 21
FYVE/PHD zinc finger CCCH zinc finger 22
Plus3-like CCCH zinc finger 22
Cytidine deaminase-like YbiA-like 21
UBC-like Endosomal sorting complex assembly domain 21
BRCT domain FYVE/PHD zinc finger 22
PreATP-grasp domain N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 21
PurM N-terminal domain-like Class I glutamine amidotransferase-like 22
TPR-like Metallo-dependent phosphatases 21
PH domain-like "Winged helix" DNA-binding domain 21
ARM repeat FabD/lysophospholipase-like 22
Pseudouridine synthase Pseudouridine synthase 22
PYP-like sensor domain (PAS domain) CheY-like 21
Alkaline phosphatase-like 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 22
RING/U-box Cyclophilin-like 21
HCP-like SMR domain-like 21
MHC antigen-recognition domain Protein kinase-like (PK-like) 22
SMAD/FHA domain PP2C-like 22
HCP-like Homing endonucleases 22
2Fe-2S ferredoxin-like alpha-helical ferredoxin 21
SAP domain RNA-binding domain, RBD 21
Glucocorticoid receptor-like (DNA-binding domain) ADP-ribosylation 21
Galactose-binding domain-like Protein kinase-like (PK-like) 21
RNA-binding domain, RBD S-adenosyl-L-methionine-dependent methyltransferases 22
PDZ domain-like (Phosphotyrosine protein) phosphatases II 22
PP2C-like Protein kinase-like (PK-like) 21
Rudiment single hybrid motif N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 21
Glutathione synthetase ATP-binding domain-like ClpP/crotonase 21
DNA primase core P-loop containing nucleoside triphosphate hydrolases 21
ARM repeat alpha/beta-Hydrolases 21
Starch-binding domain-like Starch-binding domain-like 21
FAD-linked reductases, C-terminal domain Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 21
Calponin-homology domain, CH-domain BAR/IMD domain-like 21
Nucleic acid-binding proteins S15/NS1 RNA-binding domain 21
Ran binding protein zinc finger-like DNase I-like 21
Cap-Gly domain Ubiquitin-like 22
Voltage-gated potassium channels NAD(P)-binding Rossmann-fold domains 22
FAD/NAD(P)-binding domain S-adenosyl-L-methionine-dependent methyltransferases 21
L30e-like alpha/beta knot 21
Eukaryotic type KH-domain (KH-domain type I) RNA-binding domain, RBD 21
P-loop containing nucleoside triphosphate hydrolases PABC (PABP) domain 21
Concanavalin A-like lectins/glucanases WD40 repeat-like 21
BAR/IMD domain-like P-loop containing nucleoside triphosphate hydrolases 21
Nqo1 middle domain-like Nqo1C-terminal domain-like 21
Voltage-gated potassium channels Formin homology 2 domain (FH2 domain) 22
POZ domain Tricorn protease domain 2 22
Concanavalin A-like lectins/glucanases RING/U-box 21
PGBD-like DnaJ/Hsp40 cysteine-rich domain 21
PLP-dependent transferases Ornithine decarboxylase C-terminal domain 22
Methylglyoxal synthase-like Cytidine deaminase-like 21
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 22
Acyl-CoA N-acyltransferases (Nat) BRCT domain 21
Clavaminate synthase-like Thiamin diphosphate-binding fold (THDP-binding) 21
Single hybrid motif ClpP/crotonase 21
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 22
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 21
FYVE/PHD zinc finger DNA-binding domain 21
Concanavalin A-like lectins/glucanases P-loop containing nucleoside triphosphate hydrolases 21
PDZ domain-like Rubredoxin-like 21
F-box domain LysM domain 21
Nucleotide-diphospho-sugar transferases ARM repeat 21
PurM C-terminal domain-like PurM C-terminal domain-like 22
PRC-barrel domain PRC-barrel domain 21
Glucocorticoid receptor-like (DNA-binding domain) Domain of poly(ADP-ribose) polymerase 21
Ricin B-like lectins Ricin B-like lectins 22
HAD-like HAD-like 21
Nucleic acid-binding proteins GAD domain-like 22
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 21
L9 N-domain-like Ribosomal protein L9 C-domain 21
F-box domain SET domain 21
Periplasmic binding protein-like II GlnB-like 21
"Winged helix" DNA-binding domain Protein kinase-like (PK-like) 21
FYVE/PHD zinc finger Bromodomain 21
SSo0622-like Kelch motif 22
Nucleotidyltransferase TGS-like 22
Chaperone J-domain CSL zinc finger 21
HD-domain/PDEase-like EF-hand 22
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 21
Actin-like ATPase domain Ribonuclease H-like 22
CarD-like P-loop containing nucleoside triphosphate hydrolases 21
L domain-like ARM repeat 22
DNA-binding domain Bromodomain 21
Oxygen-evolving enhancer protein 3, Cyclophilin-like 21
P-loop containing nucleoside triphosphate hydrolases DNA/RNA polymerases 22
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 21
S-adenosyl-L-methionine-dependent methyltransferases PLP-dependent transferases 21
Chromo domain-like Acyl-CoA N-acyltransferases (Nat) 21
Nucleic acid-binding proteins UBA-like 21
MHC antigen-recognition domain ARM repeat 22
C2 domain (Calcium/lipid-binding domain, CaLB) Protein kinase-like (PK-like) 22
L domain-like Galactose-binding domain-like 21
Diaminopimelate epimerase-like Diaminopimelate epimerase-like 22
eIF2alpha middle domain-like eIF-2-alpha, C-terminal domain 21
Eukaryotic type KH-domain (KH-domain type I) Retrovirus zinc finger-like domains 21
Rhomboid-like Ran binding protein zinc finger-like 22
Ankyrin repeat RCC1/BLIP-II 21
Ribokinase-like Thiamin phosphate synthase 21
Starch-binding domain-like (Trans)glycosidases 21
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 21
Glucocorticoid receptor-like (DNA-binding domain) BRCT domain 21
PRP4-like Functional domain of the splicing factor Prp18 21
L domain-like Ribonuclease H-like 22
SufE/NifU BolA-like 22
Concanavalin A-like lectins/glucanases PH domain-like 21
Adenine nucleotide alpha hydrolases-like Molybdenum cofactor biosynthesis proteins 21
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 21
ARM repeat SH3-domain 21
DNA/RNA polymerases Amine oxidase N-terminal region 21
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain Tropomyosin 21
Heat shock protein 70kD (HSP70), C-terminal subdomain Ribonuclease H-like 22
Nucleotidyltransferase EF-hand 22
Starch-binding domain-like Nucleic acid-binding proteins 22
Class II aaRS and biotin synthetases GAD domain-like 22
HMA, heavy metal-associated domain Metal cation-transporting ATPase, ATP-binding domain N 22
PLP-dependent transferases MOSC N-terminal domain-like 21
Pseudouridine synthase PUA domain-like 22
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 22
"Winged helix" DNA-binding domain E set domains 21
Protein kinase-like (PK-like) PH domain-like 21
NAD(P)-binding Rossmann-fold domains Formin homology 2 domain (FH2 domain) 22
Translation proteins PRC-barrel domain 21
Carbon-nitrogen hydrolase Adenine nucleotide alpha hydrolases-like 21
POZ domain YVTN repeat-like/Quinoprotein amine dehydrogenase 22
TGS-like Class II aaRS ABD-related 21
Heme oxygenase-like HAD-like 21
RNA-binding domain, RBD Clavaminate synthase-like 21
HD-domain/PDEase-like ACT-like 22
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 21
Ubiquitin-like Acid proteases 22
Class II aaRS and biotin synthetases Class II aaRS and biotin synthetases 22
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 21
POZ domain Galactose-binding domain-like 21
Acetyl-CoA synthetase-like ACP-like 22
Calponin-homology domain, CH-domain ARM repeat 22
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 21
Toll/Interleukin receptor TIR domain Ribonuclease H-like 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 21
TGS-like Class II aaRS and biotin synthetases 21
Radical SAM enzymes Acyl-CoA N-acyltransferases (Nat) 21
Metalloproteases ("zincins"), catalytic domain HAD-like 21
PRP4-like WD40 repeat-like 21
L domain-like FabD/lysophospholipase-like 22
4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolases 21
CCCH zinc finger HIT-like 22
DNA polymerase beta, N-terminal domain-like PsbU/PolX domain-like 21
PDZ domain-like TPR-like 21
Six-hairpin glycosidases Six-hairpin glycosidases 21
Methionyl-tRNA synthetase (MetRS), Zn-domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 22
Calcium-dependent phosphotriesterase DNA/RNA polymerases 11
UBC-like alpha/beta knot 11
P-loop containing nucleoside triphosphate hydrolases HIT-like 11
C-terminal UvrC-binding domain of UvrB ApaG-like 11
Cysteine proteinases Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain 11
Metallo-dependent hydrolases Glutamine synthetase, N-terminal domain 11
Nucleic acid-binding proteins Galactose-binding domain-like 11
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Nucleic acid-binding proteins 11
Protein prenylyltransferase Protein prenylyltransferase 11
GroEL equatorial domain-like GroEL equatorial domain-like 11
Glycerol-3-phosphate (1)-acyltransferase EF-hand 11
Eukaryotic type KH-domain (KH-domain type I) LigT-like 11
Glucocorticoid receptor-like (DNA-binding domain) S-adenosyl-L-methionine-dependent methyltransferases 11
HMA, heavy metal-associated domain Cu,Zn superoxide dismutase-like 11
Preprotein translocase SecY subunit Preprotein translocase SecY subunit 11
Calcium-dependent phosphotriesterase Calcium-dependent phosphotriesterase 11
Phospholipase D/nuclease (Trans)glycosidases 11
Ribonuclease H-like alpha/beta-Hydrolases 11
Arginase/deacetylase Arginase/deacetylase 11
HIT-like HIT-like 11
Concanavalin A-like lectins/glucanases Concanavalin A-like lectins/glucanases 11
Sec1/munc18-like (SM) proteins Sec1/munc18-like (SM) proteins 11
Class II aaRS ABD-related NAD(P)-binding Rossmann-fold domains 11
VPS9 domain VPS9 domain 11
HCP-like P-loop containing nucleoside triphosphate hydrolases 11
DNA/RNA polymerases Calcium ATPase, transmembrane domain M 11
Pectin lyase-like Rhomboid-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes Ribonuclease H-like 11
Lipoxigenase DNA/RNA polymerases 11
Chaperone J-domain FYVE/PHD zinc finger 11
Class I glutamine amidotransferase-like Nucleoside hydrolase 11
Acetyl-CoA synthetase-like Quinoprotein alcohol dehydrogenase-like 11
UBA-like P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome P450 DNA/RNA polymerases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase S13-like H2TH domain 11
Mitochondrial carrier Osmotin, thaumatin-like protein 11
Ribosomal protein S5 domain 2-like L domain-like 11
TPR-like SMR domain-like 11
Translation proteins L domain-like 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) Chromo domain-like 11
Prefoldin P-loop containing nucleoside triphosphate hydrolases 11
GYF domain SET domain 11
Ligand-binding domain in the NO signalling and Golgi transport Aminoacid dehydrogenase-like, N-terminal domain 11
D-aminoacid aminotransferase-like PLP-dependent enzymes D-aminoacid aminotransferase-like PLP-dependent enzymes 11
Phosphoglucomutase, first 3 domains TPR-like 11
Tudor/PWWP/MBT DNA repair protein MutS, domain III 11
Ypt/Rab-GAP domain of gyp1p DNA/RNA polymerases 11
Tricorn protease domain 2 DPP6 N-terminal domain-like 11
Metallo-dependent hydrolases Glutamine synthetase/guanido kinase 11
Smc hinge domain Tropomyosin 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
beta-beta-alpha zinc fingers Ribonuclease H-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
Homeodomain-like DNA/RNA polymerases 11
Class II aaRS ABD-related Aminoacid dehydrogenase-like, N-terminal domain 11
DNA repair protein MutS, domain III SMR domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Formin homology 2 domain (FH2 domain) 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
beta-sandwich domain of Sec23/24 Clavaminate synthase-like 11
RL5-like Glucocorticoid receptor-like (DNA-binding domain) 11
Thioredoxin-like DNA/RNA polymerases 11
WD40 repeat-like YhbY-like 11
alpha-D-mannose-specific plant lectins Retrovirus zinc finger-like domains 11
RNA-binding domain, RBD Ribonuclease H-like 11
Multidrug resistance efflux transporter EmrE UDP-Glycosyltransferase/glycogen phosphorylase 11
beta-sandwich domain of Sec23/24 Phospholipase D/nuclease 11
Chromo domain-like Nucleic acid-binding proteins 11
Helical scaffold and wing domains of SecA Helical scaffold and wing domains of SecA 11
Growth factor receptor domain Protein kinase-like (PK-like) 11
Di-copper centre-containing domain Di-copper centre-containing domain 11
PurS-like PurM C-terminal domain-like 11
DNA/RNA polymerases RING/U-box 11
Cysteine proteinases Cysteine proteinases 11
Tricorn protease domain 2 alpha/beta-Hydrolases 11
AN1-like Zinc finger beta-beta-alpha zinc fingers 11
Putative isomerase YbhE RING/U-box 11
ACP-like Quinoprotein alcohol dehydrogenase-like 11
DNase I-like Ribosomal protein S5 domain 2-like 11
EF-G C-terminal domain-like L domain-like 11
PUA domain-like SWIB/MDM2 domain 11
CAD & PB1 domains RING/U-box 11
(Trans)glycosidases cAMP-binding domain-like 11
Arabinanase/levansucrase/invertase Arabinanase/levansucrase/invertase 11
HydB/Nqo4-like Ribonuclease H-like 11
WD40 repeat-like Putative isomerase YbhE 11
FYVE/PHD zinc finger ARM repeat 11
Glucocorticoid receptor-like (DNA-binding domain) HAD-like 11
Lipoxigenase Ribonuclease H-like 11
Formin homology 2 domain (FH2 domain) RING/U-box 11
Cytochrome P450 P-loop containing nucleoside triphosphate hydrolases 11
Cytochrome P450 DNase I-like 11
Nudix Nudix 11
DNase I-like Hypothetical protein YjiA, C-terminal domain 11
DNA/RNA polymerases Nucleic acid-binding proteins 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) Ribonuclease H-like 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
CCCH zinc finger S-adenosyl-L-methionine-dependent methyltransferases 11
Protein kinase-like (PK-like) Retrovirus zinc finger-like domains 11
Lipoxigenase Chromo domain-like 11
Cysteine proteinases alpha/beta-Hydrolases 11
HD-domain/PDEase-like HD-domain/PDEase-like 11
Mitochondrial carrier Mitochondrial carrier 11
C2 domain (Calcium/lipid-binding domain, CaLB) alpha/beta-Hydrolases 11
Quinoprotein alcohol dehydrogenase-like Protein kinase-like (PK-like) 11
FtsH protease domain-like RNA-binding domain, RBD 11
Kelch motif Thiamin diphosphate-binding fold (THDP-binding) 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes DNA/RNA polymerases 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
SAP domain Domain of poly(ADP-ribose) polymerase 11
DPP6 N-terminal domain-like Calcium-dependent phosphotriesterase 11
Ran binding protein zinc finger-like EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
TATA-box binding protein-like DNA-glycosylase 11
Chaperone J-domain Homeodomain-like 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
Ubiquitin-like TPR-like 11
Protein kinase-like (PK-like) Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases PLP-dependent transferases 11
DNA/RNA polymerases Metal cation-transporting ATPase, ATP-binding domain N 11
Di-copper centre-containing domain Acid proteases 11
Phosphoglucomutase, first 3 domains Ribonuclease H-like 11
UBC-like Class II aaRS ABD-related 11
Lipoxigenase Acid proteases 11
Ribose/Galactose isomerase RpiB/AlsB RmlC-like cupins 11
BRCT domain DNA/RNA polymerases 11
Cytochrome f, large domain Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor 11
DNA/RNA polymerases Ribosomal protein S5 domain 2-like 11
Tubulin nucleotide-binding domain-like Tubulin nucleotide-binding domain-like 11
UDP-Glycosyltransferase/glycogen phosphorylase Retrovirus zinc finger-like domains 11
Pectin lyase-like PP2C-like 11
Chaperone J-domain beta-beta-alpha zinc fingers 11
Aldolase Aldolase 11
Hypothetical protein SAV1430 Fe-S cluster assembly (FSCA) domain-like 11
Tudor/PWWP/MBT DNA repair protein MutS, domain II 11
FGAM synthase PurL, linker domain PurM N-terminal domain-like 11
S-adenosyl-L-methionine-dependent methyltransferases Flavoproteins 11
TPR-like PUA domain-like 11
FAD-linked reductases, C-terminal domain 4Fe-4S ferredoxins 11
NAD(P)-binding Rossmann-fold domains YgbK-like 11
vWA-like Formin homology 2 domain (FH2 domain) 11
Protein kinase-like (PK-like) Ribonuclease PH domain 2-like 11
Ribosomal protein S2 Nucleotide-diphospho-sugar transferases 11
Phosphoglycerate mutase-like DNase I-like 11
ARM repeat DNA/RNA polymerases 11
(Trans)glycosidases MFS general substrate transporter 11
Starch-binding domain-like Glutathione synthetase ATP-binding domain-like 11
ISP domain Chlorophyll a-b binding protein 11
Cullin homology domain Cullin homology domain 11
Class II aaRS and biotin synthetases HD-domain/PDEase-like 11
UBC-like RING/U-box 11
PA domain Growth factor receptor domain 11
F-box domain Pectin lyase-like 11
Nucleotidylyl transferase tRNA-binding arm 11
HSP20-like chaperones DNase I-like 11
Galactose oxidase, central domain Kelch motif 11
Calponin-homology domain, CH-domain PLP-dependent transferases 11
DNA-binding pseudobarrel domain Chelatase 11
WD40 repeat-like Calcium-dependent phosphotriesterase 11
Thioredoxin-like Ypt/Rab-GAP domain of gyp1p 11
P-loop containing nucleoside triphosphate hydrolases GIY-YIG endonuclease 11
Ubiquitin-like Hect, E3 ligase catalytic domain 11
S-adenosyl-L-methionine-dependent methyltransferases Barwin-like endoglucanases 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase RING/U-box 11
Thioredoxin-like VC0467-like 11
DNA/RNA polymerases RCC1/BLIP-II 11
Homeodomain-like ITPase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
(Trans)glycosidases Thioesterase/thiol ester dehydrase-isomerase 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
ARM repeat L21p-like 11
SET domain HIT/MYND zinc finger-like 11
ABC transporter transmembrane region DNA/RNA polymerases 11
YgbK-like Aldolase 11
Thioredoxin-like Ribonuclease H-like 11
6-phosphogluconate dehydrogenase C-terminal domain-like Aldolase 11
alpha-D-mannose-specific plant lectins Acid proteases 11
beta-beta-alpha zinc fingers CCCH zinc finger 11
Hermes dimerisation domain Ribonuclease H-like 11
TPR-like P-loop containing nucleoside triphosphate hydrolases 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Homeodomain-like beta-sandwich domain of Sec23/24 11
EF-hand CAD & PB1 domains 11
Formin homology 2 domain (FH2 domain) Cysteine proteinases 11
Methionyl-tRNA synthetase (MetRS), Zn-domain Nucleic acid-binding proteins 11
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
PurS-like PurM N-terminal domain-like 11
Sec63 N-terminal domain-like DNA/RNA polymerases 11
Tropomyosin RING/U-box 11
DNase I-like FtsH protease domain-like 11
Di-copper centre-containing domain DNA/RNA polymerases 11
Starch-binding domain-like Carboxypeptidase regulatory domain-like 11
Molybdenum cofactor biosynthesis proteins Molybdenum cofactor biosynthesis proteins 11
Outer arm dynein light chain 1 Ubiquitin-like 11
F-box domain Protein kinase-like (PK-like) 11
Ribonuclease H-like Phosphoglucomutase, C-terminal domain 11
Calcium-dependent phosphotriesterase DNase I-like 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Cytochrome P450 L domain-like 11
vWA-like SAP domain 11
FMN-dependent nitroreductase-like FMN-dependent nitroreductase-like 11
Chromo domain-like Ankyrin repeat 11
C2 domain (Calcium/lipid-binding domain, CaLB) RNA-binding domain, RBD 11
Tricorn protease N-terminal domain WD40 repeat-like 11
Ligand-binding domain in the NO signalling and Golgi transport Aldolase 11
Clavaminate synthase-like Protein kinase-like (PK-like) 11
Chalcone isomerase Chalcone isomerase 11
Cullin repeat-like Cullin repeat-like 11
Homeodomain-like SET domain 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
Purple acid phosphatase, N-terminal domain Purple acid phosphatase, N-terminal domain 11
Protein kinase-like (PK-like) Class II aaRS and biotin synthetases 11
UBC-like Protein kinase-like (PK-like) 11
6-phosphogluconate dehydrogenase C-terminal domain-like YgbK-like 11
Putative isomerase YbhE DNase I-like 11
Nucleic acid-binding proteins BRCT domain 11
Class II aaRS ABD-related Class II aaRS ABD-related 11
Lipoxigenase Lipoxigenase 11
P-loop containing nucleoside triphosphate hydrolases ALDH-like 11
lambda repressor-like DNA-binding domains Cyanase C-terminal domain 11
BRCT domain Lesion bypass DNA polymerase (Y-family), little finger domain 11
POZ domain RNI-like 11
GST C-terminal domain-like DNA/RNA polymerases 11
SSo0622-like S-adenosyl-L-methionine-dependent methyltransferases 11
Cytochrome c oxidase subunit III-like beta-sandwich domain of Sec23/24 11
Cytochrome P450 6-phosphogluconate dehydrogenase C-terminal domain-like 11
Concanavalin A-like lectins/glucanases Nucleotide-diphospho-sugar transferases 11
Glucocorticoid receptor-like (DNA-binding domain) Retrovirus zinc finger-like domains 11
(Trans)glycosidases Protein kinase-like (PK-like) 11
Tudor/PWWP/MBT DNA repair protein MutS, domain I 11
POZ domain Pentapeptide repeat-like 11
S13-like H2TH domain Ribosomal protein S5 domain 2-like 11
Phosphoenolpyruvate/pyruvate domain Phosphoenolpyruvate/pyruvate domain 11
4'-phosphopantetheinyl transferase 4'-phosphopantetheinyl transferase 11
Putative isomerase YbhE YVTN repeat-like/Quinoprotein amine dehydrogenase 11
Histone-fold GST C-terminal domain-like 11
beta-sandwich domain of Sec23/24 C2 domain (Calcium/lipid-binding domain, CaLB) 11
YjgF-like YjgF-like 11
MOSC N-terminal domain-like PK beta-barrel domain-like 11
HSP20-like chaperones DNA/RNA polymerases 11
L domain-like Formin homology 2 domain (FH2 domain) 11
DNA/RNA polymerases FYVE/PHD zinc finger 11
FGAM synthase PurL, linker domain Class I glutamine amidotransferase-like 11
Cysteine proteinases WD40 repeat-like 11
Leucine zipper domain Formin homology 2 domain (FH2 domain) 11
Rudiment single hybrid motif Cytochrome f subunit of the cytochrome b6f complex, transmembrane anchor 11
Lysozyme-like Lysozyme-like 11
DNA-binding domain Aconitase iron-sulfur domain 11
WW domain S-adenosyl-L-methionine-dependent methyltransferases 11
Hermes dimerisation domain Hermes dimerisation domain 11
Translation proteins SH3-like domain Concanavalin A-like lectins/glucanases 11
alpha-D-mannose-specific plant lectins Quinoprotein alcohol dehydrogenase-like 11
alpha/beta-Hydrolases NAD(P)-binding Rossmann-fold domains 11
DNA/RNA polymerases SNARE fusion complex 11
DNase I-like Thiamin diphosphate-binding fold (THDP-binding) 11
Ligand-binding domain in the NO signalling and Golgi transport NAD(P)-binding Rossmann-fold domains 11
NAD(P)-binding Rossmann-fold domains Cytochrome P450 11
SufE/NifU NadA-like 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
Chorismate mutase II Chorismate mutase II 11
GST C-terminal domain-like Ypt/Rab-GAP domain of gyp1p 11
Protein kinase-like (PK-like) beta-lactamase/transpeptidase-like 11
YVTN repeat-like/Quinoprotein amine dehydrogenase YVTN repeat-like/Quinoprotein amine dehydrogenase 11
ARM repeat DNase I-like 11
Metalloproteases ("zincins"), catalytic domain Metalloproteases ("zincins"), catalytic domain 11
Ubiquitin-like Bromodomain 11
DNA/RNA polymerases Phosphoglucomutase, C-terminal domain 11
Enolase C-terminal domain-like alpha/beta-Hydrolases 11
HAD-like Thioredoxin-like 11
TAF(II)230 TBP-binding fragment Bromodomain 11
DNA/RNA polymerases HAD-like 11
SGNH hydrolase Pectin lyase-like 11
PUA domain-like eIF1-like 11
HCP-like Thioredoxin-like 11
Formyltransferase FMT C-terminal domain-like 11
PH domain-like DNA/RNA polymerases 11
alpha/beta knot Pectin lyase-like 11
Rhomboid-like Rhomboid-like 11
Succinyl-CoA synthetase domains Citrate synthase 11
L-aspartase-like Class II aaRS and biotin synthetases 11
HAD-like Riboflavin kinase-like 11
ADP-ribosylation ADP-ribosylation 11
DNase I-like RING/U-box 11
Amine oxidase catalytic domain Amine oxidase catalytic domain 11
"Winged helix" DNA-binding domain Ribonuclease H-like 11
PurS-like Class I glutamine amidotransferase-like 11
HAD-like NHL repeat 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
HAD-like Retrovirus zinc finger-like domains 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Ribonuclease H-like Protein kinase-like (PK-like) 11
DNA/RNA polymerases Hypothetical protein YjiA, C-terminal domain 11
Ran binding protein zinc finger-like P-loop containing nucleoside triphosphate hydrolases 11
S15/NS1 RNA-binding domain Class II aaRS ABD-related 11
PH domain-like L domain-like 11
SAP domain WGR domain-like 11
alpha-D-mannose-specific plant lectins DNA/RNA polymerases 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
Phosphoglycerate mutase-like DNA/RNA polymerases 11
NAD(P)-binding Rossmann-fold domains DNA-binding pseudobarrel domain 11
FAD/NAD(P)-binding domain 4Fe-4S ferredoxins 11
Thioredoxin-like NHL repeat 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
WD40 repeat-like C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 11
Ferritin-like Ferritin-like 11
Chlorophyll a-b binding protein Chlorophyll a-b binding protein 11
RNI-like ARM repeat 11
Double Clp-N motif Double Clp-N motif 11
DNase I-like Ribonuclease H-like 11
Calcyclin-binding protein-like HSP20-like chaperones 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) Acid proteases 11
alpha/beta-Hydrolases DNA-binding pseudobarrel domain 11
PH domain-like BSD domain-like 11
beta-sandwich domain of Sec23/24 Leucine zipper domain 11
Ribonuclease H-like Pseudouridine synthase 11
Cna protein B-type domain Carboxypeptidase regulatory domain-like 11
FAD/NAD(P)-binding domain HI0933 insert domain-like 11
Lipase/lipooxygenase domain (PLAT/LH2 domain) DNA/RNA polymerases 11
Soluble quinoprotein glucose dehydrogenase WD40 repeat-like 11
CCCH zinc finger P-loop containing nucleoside triphosphate hydrolases 11
Subtilisin-like PP2C-like 11
Macro domain-like Macro domain-like 11
PurS-like FGAM synthase PurL, linker domain 11
Tudor/PWWP/MBT P-loop containing nucleoside triphosphate hydrolases 11
NTF2-like Probable bacterial effector-binding domain 11
BRCA2 helical domain Nucleic acid-binding proteins 11
Putative isomerase YbhE ARM repeat 11
DNA repair protein MutS, domain I GIY-YIG endonuclease 11
L-aspartase-like Class II aaRS ABD-related 11
S-adenosyl-L-methionine-dependent methyltransferases Radical SAM enzymes 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
RNA-binding domain, RBD Hypothetical protein YjiA, C-terminal domain 11
HydB/Nqo4-like DNA/RNA polymerases 11
FGAM synthase PurL, linker domain PurM C-terminal domain-like 11
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 11
UBC-like Class II aaRS and biotin synthetases 11
"Winged helix" DNA-binding domain DNase I-like 11
HLH, helix-loop-helix DNA-binding domain Formin homology 2 domain (FH2 domain) 11
Protein kinase-like (PK-like) Class II aaRS ABD-related 11
ARID-like Clavaminate synthase-like 11
5' to 3' exonuclease, C-terminal subdomain Chromo domain-like 11
PIN domain-like Chromo domain-like 11
POZ domain Quinoprotein alcohol dehydrogenase-like 11
Histone-fold alpha/beta-Hydrolases 11
Phosphoglucomutase, first 3 domains DNA/RNA polymerases 11
SGNH hydrolase PP2C-like 11
Tricorn protease N-terminal domain DPP6 N-terminal domain-like 11
Acid proteases Protein kinase-like (PK-like) 11
Ran binding protein zinc finger-like Translation proteins 11
SAP domain DNase I-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes Tryptophan synthase beta subunit-like PLP-dependent enzymes 11
Adenine nucleotide alpha hydrolases-like YjgF-like 11
SAP domain ADP-ribosylation 11
BRCA2 helical domain BRCA2 tower domain 11
Cytochrome f, large domain Rudiment single hybrid motif 11
Nucleic acid-binding proteins BRCA2 tower domain 11
SAM/Pointed domain Metallo-hydrolase/oxidoreductase 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
ARM repeat Concanavalin A-like lectins/glucanases 11
Protein kinase-like (PK-like) Metalloproteases ("zincins"), catalytic domain 11
Outer arm dynein light chain 1 Protein kinase-like (PK-like) 11
HIT/MYND zinc finger-like HIT/MYND zinc finger-like 11
Putative isomerase YbhE Quinoprotein alcohol dehydrogenase-like 11
UBA-like post-AAA+ oligomerization domain-like 11
Heme-dependent peroxidases Heme-dependent peroxidases 11

Jump to [ Top of page · Add/remove domain pairs · Add/remove genomes · Domain combination pairs ]