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Acting on paired donors, with incorporation or red

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Oxidoreductases [1] <23>(183|263) (202|169|83)
0:   Acting on paired donors, with incorporation or red [1.14] <12>(35|37) (38|19|5)
- 1:   With NADH or NADPH as one donor, and incorporation [1.14.13] <156>(10|10) (12|6|2)
- 1:   Miscellaneous (requires further characterization) [1.14.99] <48>(7|5) (8|1|0)
- 1:   With 2-oxoglutarate as one donor, and incorporatio [1.14.11] <38>(6|6) (6|3|0)
- 1:   With NADH or NADPH as one donor, and incorporation [1.14.12] <23>(6|6) (6|3|1)
- 1:   With reduced flavin or flavoprotein as one donor, [1.14.14] <13>(4|5) (7|3|1)
- 1:   With oxidation of a pair of donors resulting in th [1.14.19] <10>(1|1) (2|0|0)
- 1:   With NADH or NADPH as one donor, and the other deh [1.14.21] <8>(0|0) (0|0|0)
- 1:   With a reduced iron-sulfur protein as one donor, a [1.14.15] <8>(3|2) (3|1|0)
- 1:   With reduced pteridine as one donor, and incorpora [1.14.16] <6>(2|2) (2|1|0)
- 1:   With reduced ascorbate as one donor, and incorpora [1.14.17] <4>(2|2) (4|1|0)
- 1:   With another compound as one donor, and incorporat [1.14.18] <3>(5|3) (5|3|1)
- 1:   With 2-oxoglutarate as one donor, and the other de [1.14.20] <2>(0|0) (1|0|0)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
Hemocyanin, N-terminal domain0Direct
Globin-like0Direct
PHM/PNGase F0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
TPR-like0Direct
FYVE/PHD zinc finger0Direct
Ferritin-like0Direct
Bacterial luciferase-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Di-copper centre-containing domain0Direct
EGF/Laminin0Direct
Cytochrome P4500Direct
Clavaminate synthase-like0Direct
ARM repeat0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
Riboflavin synthase domain-like0Direct
Bet v1-like0Direct
ISP domain0Direct
NTF2-like0Direct
Heme oxygenase-like0.000000000000003708Direct
ACT-like0.000000000000003708Direct
Dimeric alpha+beta barrel0.000000000000005545Direct
FAD/NAD(P)-binding domain0.0000000000001853Direct
Flavoproteins0.0000000001761Direct
SMAD/FHA domain0.00000000823Direct
RNI-like0.0000000175Direct
PDZ domain-like0.0003073Direct
Metallo-hydrolase/oxidoreductase0.003632Inherited
E set domains0.04627Inherited
Acyl-CoA dehydrogenase NM domain-like0.1185Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.1248Inherited
Nucleotide-diphospho-sugar transferases0.8741Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Heme-dependent peroxidases1Inherited
FAD-linked reductases, C-terminal domain1Inherited


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Family

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SCOP term FDR (all) Annotation (direct or inherited)
PHBH-like0Direct
Globins0Direct
Peptidylglycine alpha-hydroxylating monooxygenase, PHM0Direct
Arthropod hemocyanin, C-terminal domain0Direct
EGF-type module0Direct
Hemocyanin, N-terminal domain0Direct
Eukaryotic type heme oxygenase0Direct
Penicillin synthase-like0Direct
Ring hydroxylating beta subunit0Direct
Flavohemoglobin, C-terminal domain0Direct
Tetratricopeptide repeat (TPR)0Direct
Cytochrome P4500Direct
Phenylalanine metabolism regulatory domain0Direct
PhyH-like0Direct
Ring hydroxylating alpha subunit ISP domain0Direct
Ribonucleotide reductase-like0Direct
Bacterial luciferase (alkanal monooxygenase)0Direct
Hypoxia-inducible factor HIF ihhibitor (FIH1)0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
PG130-like0Direct
Ferredoxin reductase FAD-binding domain-like0Direct
Ssud-like monoxygenases0Direct
Hemocyanin middle domain0Direct
Ring hydroxylating alpha subunit catalytic domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00000000000004152Direct
Cytochrome p450 reductase N-terminal domain-like0.000000000000957Direct
NADPH-cytochrome p450 reductase-like0.000000000001061Direct
FAD-linked reductases, N-terminal domain0.0000000003369Direct
PHD domain0.0000000007451Direct
Myeloperoxidase-like0.00000000148Direct
FHA domain0.000000001588Direct
PDZ domain0.00000000242Direct
Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains0.001184Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.002112Inherited
Medium chain acyl-CoA dehydrogenase-like, C-terminal domain0.01339Inherited
Tandem AAA-ATPase domain1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ARM repeat0Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0Direct
TPR-like0Direct
Bacterial luciferase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Ferritin-like0Direct
Cytochrome P4500Direct
Globin-like0Direct
ISP domain0Direct
Bet v1-like0Direct
EGF/Laminin0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
FYVE/PHD zinc finger0Direct
Di-copper centre-containing domain0Direct
Clavaminate synthase-like0Direct
PHM/PNGase F0Direct
Hemocyanin, N-terminal domain0Direct
NTF2-like0Direct
Riboflavin synthase domain-like0Direct
Heme oxygenase-like0.000000000000003816Direct
ACT-like0.000000000000003816Direct
Dimeric alpha+beta barrel0.000000000000004848Direct
FAD/NAD(P)-binding domain0.0000000000003594Direct
Flavoproteins0.000000000182Direct
NHL repeat0.00000000148Direct
SMAD/FHA domain0.000000007062Direct
RNI-like0.00000001522Direct
PDZ domain-like0.0002756Direct
Calcium-dependent phosphotriesterase0.0004185Direct
Metallo-hydrolase/oxidoreductase0.003421Inherited
E set domains0.04353Inherited
Acyl-CoA dehydrogenase NM domain-like0.1125Inherited
Acyl-CoA dehydrogenase C-terminal domain-like0.1185Inherited
Cytochrome b5-like heme/steroid binding domain0.4399Inherited
Nucleotide-diphospho-sugar transferases0.9357Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
Heme-dependent peroxidases1Inherited
FAD-linked reductases, C-terminal domain1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
51905,51905
  • 51905 - FAD/NAD(P)-binding domain
  • 51905 - FAD/NAD(P)-binding domain
  • 0Direct
    46458,63380
  • 46458 - Globin-like
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    48264,52218
  • 48264 - Cytochrome P450
  • 52218 - Flavoproteins
  • 0Direct
    50022,55961
  • 50022 - ISP domain
  • 55961 - Bet v1-like
  • 0Direct
    56512,52218
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 0Direct
    48050,48056
  • 48050 - Hemocyanin, N-terminal domain
  • 48056 - Di-copper centre-containing domain
  • 0Direct
    48056,81296
  • 48056 - Di-copper centre-containing domain
  • 81296 - E set domains
  • 0Direct
    48452,51197
  • 48452 - TPR-like
  • 51197 - Clavaminate synthase-like
  • 0Direct
    57196,48113
  • 57196 - EGF/Laminin
  • 48113 - Heme-dependent peroxidases
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    50022,56281
  • 50022 - ISP domain
  • 56281 - Metallo-hydrolase/oxidoreductase
  • 0Direct
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.000000000002259Direct
    54292,63380
  • 54292 - 2Fe-2S ferredoxin-like
  • 63380 - Riboflavin synthase domain-like
  • 0.0003929Direct
    52218,63380
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0.003782Inherited
    56645,47203
  • 56645 - Acyl-CoA dehydrogenase NM domain-like
  • 47203 - Acyl-CoA dehydrogenase C-terminal domain-like
  • 0.1125Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.9678Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56512,52218,63380
  • 56512 - Nitric oxide (NO) synthase oxygenase domain
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    46458,63380,52343
  • 46458 - Globin-like
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0Direct
    48050,48056,81296
  • 48050 - Hemocyanin, N-terminal domain
  • 48056 - Di-copper centre-containing domain
  • 81296 - E set domains
  • 0Direct
    48264,52218,63380
  • 48264 - Cytochrome P450
  • 52218 - Flavoproteins
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    54292,63380,52343
  • 54292 - 2Fe-2S ferredoxin-like
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.0003929Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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