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Acting on the aldehyde or oxo group of donors

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Oxidoreductases [1] <23>(183|263) (202|169|83)
0:   Acting on the aldehyde or oxo group of donors [1.2] <8>(26|32) (27|22|10)
- 1:   With NAD(+) or NADP(+) as acceptor [1.2.1] <84>(13|12) (14|10|3)
- 1:   With oxygen as acceptor [1.2.3] <14>(6|6) (7|5|4)
- 1:   With an iron-sulfur protein as acceptor [1.2.7] <10>(6|6) (6|4|2)
- 1:   With other acceptors [1.2.99] <7>(3|2) (8|4|0)
- 1:   With a cytochrome as acceptor [1.2.2] <4>(0|0) (0|0|0)
- 1:   With a disulfide as acceptor [1.2.4] <4>(2|6) (2|2|1)
- 1:   With a quinone or similar compound as acceptor [1.2.5] <1>(0|0) (0|0|0)
- 1:   With other, known, acceptors [1.2.98](0|0) (0|0|0)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
TK C-terminal domain-like0Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III0Direct
Glutamyl tRNA-reductase catalytic, N-terminal domain0Direct
Prismane protein-like0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Aldehyde ferredoxin oxidoreductase, C-terminal domains0Direct
Aldehyde ferredoxin oxidoreductase, N-terminal domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Glutamyl tRNA-reductase dimerization domain0Direct
NAD(P)-binding Rossmann-fold domains0Direct
ALDH-like0Direct
CO dehydrogenase ISP C-domain like0.00000001062Direct
Molybdenum cofactor-binding domain0.00000004553Direct
CO dehydrogenase molybdoprotein N-domain-like0.0000001077Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.0000002543Direct
ACP-like0.0006292Direct
Alpha subunit of glutamate synthase, C-terminal domain0.0007678Direct
2Fe-2S ferredoxin-like0.03282Inherited
CoA-dependent acyltransferases0.06325Inherited
alpha-helical ferredoxin0.08933Inherited
Acetyl-CoA synthetase-like0.6517Inherited
ADC-like0.8366Inherited
4Fe-4S ferredoxins1Inherited
Formate dehydrogenase/DMSO reductase, domains 1-31Inherited
Formate/glycerate dehydrogenase catalytic domain-like1Inherited
FAD-binding/transporter-associated domain-like1Inherited


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Family

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SCOP term FDR (all) Annotation (direct or inherited)
GAPDH-like0Direct
Glutamyl tRNA-reductase dimerization domain0Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
Branched-chain alpha-keto acid dehydrogenase PP module0Direct
Aldehyde ferredoxin oxidoreductase, C-terminal domains0Direct
ALDH-like0Direct
Aldehyde ferredoxin oxidoreductase, N-terminal domain0Direct
Carbon monoxide dehydrogenase0Direct
Branched-chain alpha-keto acid dehydrogenase Pyr module0Direct
PFOR Pyr module0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain0Direct
Aminoacid dehydrogenase-like, C-terminal domain0Direct
Glutamyl tRNA-reductase catalytic, N-terminal domain0Direct
PFOR PP module0.000000000005451Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain II0.000000000186Direct
CO dehydrogenase ISP C-domain like0.00000001521Direct
Transketolase C-terminal domain-like0.00000005543Direct
Molybdenum cofactor-binding domain0.00000006641Direct
CO dehydrogenase molybdoprotein N-domain-like0.0000001525Direct
CO dehydrogenase flavoprotein N-terminal domain-like0.0000003499Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.0000003499Direct
TK-like Pyr module0.000005918Direct
Alpha subunit of glutamate synthase, C-terminal domain0.000884Direct
TK-like PP module0.008557Inherited
2Fe-2S ferredoxin domains from multidomain proteins0.02409Inherited
Acetyl-CoA synthetase-like0.6557Inherited
PyrH-like0.9075Inherited
Formate dehydrogenase/DMSO reductase, C-terminal domain0.9446Inherited
Formate/glycerate dehydrogenases, substrate-binding domain1Inherited
Formate dehydrogenase/DMSO reductase, domains 1-31Inherited
Formate/glycerate dehydrogenases, NAD-domain1Inherited


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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
TK C-terminal domain-like0Direct
Glutamyl tRNA-reductase dimerization domain0Direct
NAD(P)-binding Rossmann-fold domains0Direct
Aldehyde ferredoxin oxidoreductase, N-terminal domain0Direct
ALDH-like0Direct
Prismane protein-like0Direct
Aldehyde ferredoxin oxidoreductase, C-terminal domains0Direct
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain0Direct
Thiamin diphosphate-binding fold (THDP-binding)0Direct
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III0Direct
Glutamyl tRNA-reductase catalytic, N-terminal domain0Direct
CO dehydrogenase ISP C-domain like0.00000004827Direct
Molybdenum cofactor-binding domain0.0000001545Direct
CO dehydrogenase molybdoprotein N-domain-like0.0000003639Direct
CO dehydrogenase flavoprotein C-terminal domain-like0.0000008582Direct
ACP-like0.0005246Direct
Alpha subunit of glutamate synthase, C-terminal domain0.0006376Direct
2Fe-2S ferredoxin-like0.03545Inherited
CoA-dependent acyltransferases0.05572Inherited
alpha-helical ferredoxin0.07847Inherited
Acetyl-CoA synthetase-like0.607Inherited
ADC-like0.7824Inherited
Formate dehydrogenase/DMSO reductase, domains 1-31Inherited
FAD-binding/transporter-associated domain-like1Inherited
Formate/glycerate dehydrogenase catalytic domain-like1Inherited
RmlC-like cupins1Inherited
4Fe-4S ferredoxins1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
69336,50692
  • 69336 - Alpha subunit of glutamate synthase, C-terminal domain
  • 50692 - ADC-like
  • 0Direct
    69742,51735
  • 69742 - Glutamyl tRNA-reductase catalytic, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    53633,53720
  • 53633 - Carbamate kinase-like
  • 53720 - ALDH-like
  • 0Direct
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    56228,48310
  • 56228 - Aldehyde ferredoxin oxidoreductase, N-terminal domain
  • 48310 - Aldehyde ferredoxin oxidoreductase, C-terminal domains
  • 0Direct
    51735,69075
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 69075 - Glutamyl tRNA-reductase dimerization domain
  • 0Direct
    52518,54862
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    53720,56796
  • 53720 - ALDH-like
  • 56796 - Dehydroquinate synthase-like
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    56821,46548
  • 56821 - Prismane protein-like
  • 46548 - alpha-helical ferredoxin
  • 0Direct
    54292,47741
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 0.00000004827Direct
    55447,54665
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0.00000005417Direct
    52777,56801
  • 52777 - CoA-dependent acyltransferases
  • 56801 - Acetyl-CoA synthetase-like
  • 0.0000001464Direct
    54665,56003
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0.0000003639Direct
    47741,56176
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0.0000003721Direct
    56176,55447
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 0.0000008582Direct
    52922,52518
  • 52922 - TK C-terminal domain-like
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0.000003755Direct
    54862,53706
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.1857Inherited
    54292,54862
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 0.2015Inherited
    53706,50692
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0.9484Inherited
    52283,51735
  • 52283 - Formate/glycerate dehydrogenase catalytic domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    69742,51735,69075
  • 69742 - Glutamyl tRNA-reductase catalytic, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 69075 - Glutamyl tRNA-reductase dimerization domain
  • 0Direct
    52922,52518,54862
  • 52922 - TK C-terminal domain-like
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 54862 - 4Fe-4S ferredoxins
  • 0Direct
    52518,52922,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0Direct
    56176,55447,54665
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 0.00000005417Direct
    55447,54665,56003
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 54665 - CO dehydrogenase molybdoprotein N-domain-like
  • 56003 - Molybdenum cofactor-binding domain
  • 0.00000005417Direct
    47741,56176,55447
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55447 - CO dehydrogenase flavoprotein C-terminal domain-like
  • 0.0000003721Direct
    54292,47741,56176
  • 54292 - 2Fe-2S ferredoxin-like
  • 47741 - CO dehydrogenase ISP C-domain like
  • 56176 - FAD-binding/transporter-associated domain-like
  • 0.0000003721Direct
    54862,53706,50692
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 50692 - ADC-like
  • 0.001183Inherited
    54292,54862,53706
  • 54292 - 2Fe-2S ferredoxin-like
  • 54862 - 4Fe-4S ferredoxins
  • 53706 - Formate dehydrogenase/DMSO reductase, domains 1-3
  • 0.1857Inherited
    52518,52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0.4113Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)