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Acyltransferases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Transferases [2] <10>(363|551) (398|460|240)
0:   Acyltransferases [2.3] <3>(56|73) (63|47|19)
- 1:   Transferring groups other than amino-acyl groups [2.3.1] <202>(44|55) (48|33|12)
- 1:   Aminoacyltransferases [2.3.2] <18>(10|12) (10|7|3)
- 1:   Acyl groups converted into alkyl on transfer [2.3.3] <15>(9|9) (12|9|4)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
Nucleotide-diphospho-sugar transferases0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
FabD/lysophospholipase-like0Direct
CoA-dependent acyltransferases0Direct
Kix domain of CBP (creb binding protein)0Direct
Malate synthase G0Direct
Aldolase0Direct
Class I glutamine amidotransferase-like0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
DmpA/ArgJ-like0Direct
ACP-like0Direct
Thiolase-like0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
Citrate synthase0Direct
TAZ domain0Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
Class II aaRS and biotin synthetases0Direct
alpha/beta-Hydrolases0Direct
Single hybrid motif0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
post-HMGL domain-like0Direct
HprK N-terminal domain-like0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Gamma-glutamyl cyclotransferase-like0Direct
Trimeric LpxA-like enzymes0Direct
Transglutaminase, two C-terminal domains0Direct
Chromo domain-like0Direct
TTHA0583/YokD-like0Direct
Bromodomain0.00000000000488Direct
Cysteine proteinases0.0000000005621Direct
SCP-like0.00000001291Direct
Acetyl-CoA synthetase-like0.000004143Direct
RING/U-box0.00005885Direct
PFL-like glycyl radical enzymes0.0000868Direct
FYVE/PHD zinc finger0.0001717Direct
PLP-dependent transferases0.0003341Direct
PYP-like sensor domain (PAS domain)0.2631Inherited
EF-hand0.3916Inherited
Thioesterase/thiol ester dehydrase-isomerase0.7795Inherited
Succinyl-CoA synthetase domains0.9255Inherited
GroES-like0.9404Inherited
E set domains1Inherited
Carbamate kinase-like1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
"Winged helix" DNA-binding domain1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Zn-dependent exopeptidases1Inherited
Nucleic acid-binding proteins1Inherited
tRNA-binding arm1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Radical SAM enzymes1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP term FDR (all) Annotation (direct or inherited)
Chromo barrel domain0Direct
FabD-like0Direct
Malate synthase G0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
CAT-like0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
O-acetyltransferase0Direct
Nuclear receptor coactivator interlocking domain0Direct
Thiolase-related0Direct
UDP-glucose pyrophosphorylase0Direct
Phytochelatin synthase0Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
Acyl-carrier protein (ACP)0Direct
Transglutaminase core0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Chalcone synthase-like0Direct
LFTR-like0Direct
TAZ domain0Direct
Glutaminyl-peptide cyclotransferase-like0Direct
Galactoside acetyltransferase-like0Direct
N-acetyl transferase, NAT0Direct
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD0Direct
PlsX-like0Direct
Kix domain of CBP (creb binding protein)0Direct
Autoinducer synthetase0Direct
Gamma-glutamyl cyclotransferase-like0Direct
HMGL-like0Direct
DmpG/LeuA communication domain-like0Direct
Serine acetyltransferase0Direct
Arylamine N-acetyltransferase0Direct
DRTGG domain0Direct
ArgJ-like0Direct
Citrate synthase0Direct
LplA-like0Direct
N-myristoyl transferase, NMT0Direct
GlmU C-terminal domain-like0Direct
HTS-like0Direct
Gamma-glutamyltranspeptidase-like0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
ZZ domain0Direct
Choline/Carnitine O-acyltransferase0Direct
Methicillin resistance protein FemA probable tRNA-binding arm0Direct
FemXAB nonribosomal peptidyltransferases0Direct
Hypoxia-inducible factor Hif2a, C-terminal domain0Direct
Biotinyl/lipoyl-carrier proteins and domains0Direct
PFL-like0Direct
Transglutaminase, two C-terminal domains0Direct
Phosphotransacetylase0Direct
Aminoglycoside 3-N-acetyltransferase-like0Direct
UDP N-acetylglucosamine acyltransferase0Direct
Transglutaminase N-terminal domain0Direct
AstA-like0Direct
GABA-aminotransferase-like0Direct
Bromodomain0.000000000004852Direct
Sterol carrier protein, SCP0.000000008017Direct
CoA-binding domain0.00000005369Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.0000001023Direct
Acetyl-CoA synthetase-like0.000001451Direct
MaoC-like0.00001772Direct
PHD domain0.00001956Direct
Chromo domain0.03616Inherited
Calmodulin-like0.5285Inherited
N-acetyl-l-glutamate kinase0.7045Inherited
Alcohol dehydrogenase-like, C-terminal domain0.7769Inherited
Succinyl-CoA synthetase domains0.8199Inherited
Tyrosine-dependent oxidoreductases0.8807Inherited
Alcohol dehydrogenase-like, N-terminal domain0.9168Inherited
Crotonase-like0.9759Inherited
Anticodon-binding domain1Inherited
Succinyl-CoA synthetase, beta-chain, N-terminal domain1Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain1Inherited


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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Trimeric LpxA-like enzymes0Direct
Isocitrate/Isopropylmalate dehydrogenase-like0Direct
Class II aaRS and biotin synthetases0Direct
Acyl-CoA N-acyltransferases (Nat)0Direct
post-HMGL domain-like0Direct
Aldolase0Direct
Nucleotide-diphospho-sugar transferases0Direct
ACP-like0Direct
DmpA/ArgJ-like0Direct
CCHHC domain0Direct
Single hybrid motif0Direct
Citrate synthase0Direct
alpha/beta-Hydrolases0Direct
Chromo domain-like0Direct
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain0Direct
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex0Direct
Nuclear receptor coactivator interlocking domain0Direct
FabD/lysophospholipase-like0Direct
Kix domain of CBP (creb binding protein)0Direct
Malate synthase G0Direct
HLH, helix-loop-helix DNA-binding domain0Direct
Docking domain B of the erythromycin polyketide synthase (DEBS)0Direct
Glycerol-3-phosphate (1)-acyltransferase0Direct
Thiolase-like0Direct
CoA-dependent acyltransferases0Direct
Gamma-glutamyl cyclotransferase-like0Direct
TTHA0583/YokD-like0Direct
Class I glutamine amidotransferase-like0Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0Direct
TAZ domain0Direct
Transglutaminase, two C-terminal domains0Direct
Formylmethanofuran:tetrahydromethanopterin formyltransferase0Direct
HprK N-terminal domain-like0Direct
Bromodomain0.000000000003381Direct
Cysteine proteinases0.0000000005209Direct
SCP-like0.0000000101Direct
Acetyl-CoA synthetase-like0.000003187Direct
PFL-like glycyl radical enzymes0.00007056Direct
RING/U-box0.00007756Direct
FYVE/PHD zinc finger0.0001353Direct
PLP-dependent transferases0.0002029Direct
PYP-like sensor domain (PAS domain)0.2349Inherited
Dimeric alpha+beta barrel0.239Inherited
EF-hand0.3556Inherited
Thioesterase/thiol ester dehydrase-isomerase0.7503Inherited
Succinyl-CoA synthetase domains0.869Inherited
GroES-like0.8835Inherited
E set domains0.9859Inherited
Zn-dependent exopeptidases1Inherited
4'-phosphopantetheinyl transferase1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Nucleic acid-binding proteins1Inherited
FMN-linked oxidoreductases1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
DHS-like NAD/FAD-binding domain1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Radical SAM enzymes1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
tRNA-binding arm1Inherited
"Winged helix" DNA-binding domain1Inherited
Carbamate kinase-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47005,52777
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    52777,52777
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    81296,54001
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 0Direct
    52210,51735
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    69593,47473
  • 69593 - Glycerol-3-phosphate (1)-acyltransferase
  • 47473 - EF-hand
  • 0Direct
    53901,53901
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0Direct
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0Direct
    57850,57933
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0Direct
    51230,47005
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    46785,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    52540,75138
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 75138 - HprK N-terminal domain-like
  • 0Direct
    51230,52777
  • 51230 - Single hybrid motif
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    52540,55729
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    102114,55729
  • 102114 - Radical SAM enzymes
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    89000,110921
  • 89000 - post-HMGL domain-like
  • 110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    55729,47370
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 47370 - Bromodomain
  • 0Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0Direct
    55729,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    51735,48256
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48256 - Citrate synthase
  • 0Direct
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0Direct
    69593,56801
  • 69593 - Glycerol-3-phosphate (1)-acyltransferase
  • 56801 - Acetyl-CoA synthetase-like
  • 0Direct
    53633,55729
  • 53633 - Carbamate kinase-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    49309,49309
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    47459,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    51569,54909
  • 51569 - Aldolase
  • 54909 - Dimeric alpha+beta barrel
  • 0Direct
    55729,46589
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 46589 - tRNA-binding arm
  • 0Direct
    54160,55729
  • 54160 - Chromo domain-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    51230,51230
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 0Direct
    75138,53659
  • 75138 - HprK N-terminal domain-like
  • 53659 - Isocitrate/Isopropylmalate dehydrogenase-like
  • 0Direct
    55112,55112
  • 55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
  • 55112 - Formylmethanofuran:tetrahydromethanopterin formyltransferase
  • 0Direct
    53901,55718
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0Direct
    46589,55729
  • 46589 - tRNA-binding arm
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    54001,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.00000000009644Direct
    47336,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 0.0002122Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.007373Inherited
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.03575Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.2929Inherited
    56059,52210
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 0.7303Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.8757Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 1Inherited
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55729,46589,55729
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 46589 - tRNA-binding arm
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0Direct
    57850,57850,57933
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57933 - TAZ domain
  • 0Direct
    46785,57903,57903
  • 46785 - "Winged helix" DNA-binding domain
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    51230,51230,47005
  • 51230 - Single hybrid motif
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 0Direct
    51569,89000,110921
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 110921 - 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain
  • 0Direct
    51230,47005,52777
  • 51230 - Single hybrid motif
  • 47005 - Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex
  • 52777 - CoA-dependent acyltransferases
  • 0Direct
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    51735,50129,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53901,53901,55718
  • 53901 - Thiolase-like
  • 53901 - Thiolase-like
  • 55718 - SCP-like
  • 0Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    52540,75138,53659
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 75138 - HprK N-terminal domain-like
  • 53659 - Isocitrate/Isopropylmalate dehydrogenase-like
  • 0Direct
    52210,51735,48256
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48256 - Citrate synthase
  • 0Direct
    54001,49309,49309
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    81296,54001,49309
  • 81296 - E set domains
  • 54001 - Cysteine proteinases
  • 49309 - Transglutaminase, two C-terminal domains
  • 0Direct
    56059,52210,51735
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52210 - Succinyl-CoA synthetase domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    47336,52777,52777
  • 47336 - ACP-like
  • 52777 - CoA-dependent acyltransferases
  • 52777 - CoA-dependent acyltransferases
  • 0.0002122Direct
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited


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