SUPERFAMILY 1.75 HMM library and genome assignments server

Transferring alkyl or aryl groups, other than meth

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Transferases [2] <10>(363|551) (398|460|240)
0:   Transferring alkyl or aryl groups, other than meth [2.5] <1>(33|36) (36|18|8)
- 1:   Transferring alkyl or aryl groups, other than meth [2.5.1] <101>(33|36) (36|18|8)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
EPT/RTPC-like0Direct
Cobalamin adenosyltransferase-like0Direct
Thioredoxin-like0Direct
S-adenosylmethionine synthetase0Direct
DHS-like NAD/FAD-binding domain0Direct
Terpenoid synthases0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Aldolase0Direct
NadA-like0Direct
Thiamin phosphate synthase0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
Undecaprenyl diphosphate synthase0Direct
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
Protein prenylyltransferase0Direct
GST C-terminal domain-like0Direct
Periplasmic binding protein-like II0Direct
Lumazine synthase0Direct
Dihydropteroate synthetase-like6.915e-15Direct
Dehydroquinate synthase-like8.279e-15Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes3.726e-13Direct
MAPEG domain-like9.525e-13Direct
Terpenoid cyclases/Protein prenyltransferases2.554e-09Direct
FMN-linked oxidoreductases1.014e-07Direct
FAD-linked oxidases, C-terminal domain5.662e-06Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.001085Inherited
Aminoacid dehydrogenase-like, N-terminal domain0.007779Inherited
Riboflavin synthase domain-like0.03018Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Ribokinase-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
PLP-dependent transferases1Inherited
Radical SAM enzymes1Inherited
FAD-binding/transporter-associated domain-like1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP term FDR (all) Annotation (direct or inherited)
Class I DAHP synthetase0Direct
Protein prenylyltransferase0Direct
Squalene synthase0Direct
Glutathione S-transferase (GST), N-terminal domain0Direct
Class-II DAHP synthetase0Direct
Enolpyruvate transferase, EPT0Direct
Glutathione S-transferase (GST), C-terminal domain0Direct
Thiamin phosphate synthase0Direct
Protein prenyltransferases0Direct
DsbA-like0Direct
Dihydropteroate synthetase0Direct
Deoxyhypusine synthase, DHS0Direct
Undecaprenyl diphosphate synthase0Direct
Isoprenyl diphosphate synthases0Direct
NadA-like0Direct
Spermidine synthase0Direct
Dehydroquinate synthase, DHQS0Direct
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
Lumazine synthase0Direct
Phosphate binding protein-like0Direct
S-adenosylmethionine synthetase0Direct
Shikimate dehydrogenase-like0Direct
Cobalamin adenosyltransferase0Direct
Riboflavin synthase0Direct
SepSecS-like0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes3.43e-15Direct
MAPEG domain2.167e-13Direct
FMN-linked oxidoreductases1.814e-09Direct
Shikimate kinase (AroK)6.825e-07Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.0006195Direct
Class I aldolase0.004784Inherited
Cystathionine synthase-like1Inherited
Thiamin biosynthesis kinases1Inherited
Biotin synthase1Inherited
Aminoacid dehydrogenase-like, C-terminal domain1Inherited


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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lumazine synthase0Direct
Protein prenylyltransferase0Direct
Cobalamin adenosyltransferase-like0Direct
Aldolase0Direct
Thiamin phosphate synthase0Direct
Thioredoxin-like0Direct
Terpenoid synthases0Direct
DHS-like NAD/FAD-binding domain0Direct
Undecaprenyl diphosphate synthase0Direct
EPT/RTPC-like0Direct
NadA-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
GST C-terminal domain-like0Direct
Periplasmic binding protein-like II0Direct
Rab geranylgeranyltransferase alpha-subunit, insert domain0Direct
S-adenosylmethionine synthetase0Direct
Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain0Direct
Dihydropteroate synthetase-like4.848e-15Direct
Dehydroquinate synthase-like5.537e-15Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes2.527e-13Direct
MAPEG domain-like7.024e-13Direct
Terpenoid cyclases/Protein prenyltransferases2.132e-09Direct
MFS general substrate transporter4.289e-08Direct
FMN-linked oxidoreductases7.476e-08Direct
Outer arm dynein light chain 12.465e-07Direct
FAD-linked oxidases, C-terminal domain4.563e-06Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.0008906Direct
Aminoacid dehydrogenase-like, N-terminal domain0.00641Inherited
Riboflavin synthase domain-like0.02604Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
FAD-binding/transporter-associated domain-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Radical SAM enzymes1Inherited
PLP-dependent transferases1Inherited
Ribokinase-like1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    55205,52540
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49594,52075
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 52075 - Outer arm dynein light chain 1
  • 0Direct
    55083,51717
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    48439,49594
  • 48439 - Protein prenylyltransferase
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 0Direct
    63380,63380
  • 63380 - Riboflavin synthase domain-like
  • 63380 - Riboflavin synthase domain-like
  • 0Direct
    51391,53613
  • 51391 - Thiamin phosphate synthase
  • 53613 - Ribokinase-like
  • 0Direct
    51569,53223
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    103473,53335
  • 103473 - MFS general substrate transporter
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0Direct
    52540,51569
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    53850,54782
  • 53850 - Periplasmic binding protein-like II
  • 54782 - Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
  • 0Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0Direct
    56796,55205
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 0Direct
    56176,55103
  • 56176 - FAD-binding/transporter-associated domain-like
  • 55103 - FAD-linked oxidases, C-terminal domain
  • 4.563e-06Direct
    55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 3.472e-05Direct
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.001106Inherited
    55620,55620
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 0.02081Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    56796,55205,52540
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55620,55083,51717
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    51569,53223,51735
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    55205,52540,51569
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    55620,55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    48439,49594,52075
  • 48439 - Protein prenylyltransferase
  • 49594 - Rab geranylgeranyltransferase alpha-subunit, insert domain
  • 52075 - Outer arm dynein light chain 1
  • 0Direct
    52540,51569,53223
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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