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Transferring phosphorous-containing groups

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Transferases [2] <10>(363|551) (398|460|240)
0:   Transferring phosphorous-containing groups [2.7] <13>(220|294) (251|300|176)
- 1:   Phosphotransferases with an alcohol group as accep [2.7.1] <180>(55|80) (65|52|24)
- 1:   Nucleotidyltransferases [2.7.7] <86>(89|111) (98|96|59)
- 1:   Transferases for other substituted phosphate group [2.7.8] <36>(6|3) (7|1|0)
- 1:   Protein-serine/threonine kinases [2.7.11] <31>(46|50) (57|86|38)
- 1:   Phosphotransferases with a phosphate group as acce [2.7.4] <25>(19|16) (21|16|7)
- 1:   Phosphotransferases with a carboxyl group as accep [2.7.2] <15>(8|9) (8|8|3)
- 1:   Phosphotransferases with a nitrogenous group as ac [2.7.3] <12>(7|7) (7|6|5)
- 1:   Diphosphotransferases [2.7.6] <5>(10|8) (10|7|3)
- 1:   Phosphotransferases with paired acceptors [2.7.9] <5>(5|5) (5|3|1)
- 1:   Protein-histidine kinases [2.7.13] <3>(12|17) (12|23|21)
- 1:   Dual-specificity kinases (those acting on Ser/Thr [2.7.12] <2>(1|1) (3|2|0)
- 1:   Protein-tyrosine kinases [2.7.10] <2>(19|24) (26|31|22)
- 1:   Other protein kinases [2.7.99] <1>(0|0) (0|0|0)


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain0Direct
SH3-domain0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
HPr-like0Direct
Immunoglobulin0Direct
Nucleotide-diphospho-sugar transferases0Direct
Sensory domain-like0Direct
PH domain-like0Direct
RCC1/BLIP-II0Direct
Nucleotidyltransferase substrate binding subunit/domain0Direct
AF1531-like0Direct
PPK N-terminal domain-like0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
DNA/RNA polymerases0Direct
DNA-binding domain of retroviral integrase0Direct
Retrovirus capsid dimerization domain-like0Direct
CheW-like0Direct
Riboflavin kinase-like0Direct
RPB5-like RNA polymerase subunit0Direct
Nucleoside diphosphate kinase, NDK0Direct
Ribonuclease PH domain 2-like0Direct
Carbamate kinase-like0Direct
RNI-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Fibronectin type III0Direct
Myosin rod fragments0Direct
SAM/Pointed domain0Direct
MAST3 pre-PK domain-like0Direct
Acid proteases0Direct
Flavivirus capsid protein C0Direct
CofD-like0Direct
Sema domain0Direct
Ribonuclease H-like0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
Cysteine-rich domain0Direct
DNA clamp0Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0Direct
SH2 domain0Direct
Positive stranded ssRNA viruses0Direct
KA1-like0Direct
GroEL apical domain-like0Direct
PHP14-like0Direct
Phosphohistidine domain0Direct
GHMP Kinase, C-terminal domain0Direct
post-AAA+ oligomerization domain-like0Direct
CheY-binding domain of CheA0Direct
EndoU-like0Direct
Ribosomal protein S5 domain 2-like0Direct
PHP domain-like0Direct
Protein kinase-like (PK-like)0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Insert subdomain of RNA polymerase alpha subunit0Direct
Poly A polymerase C-terminal region-like0Direct
Sporulation response regulatory protein Spo0B0Direct
PUA domain-like0Direct
Growth factor receptor domain0Direct
PK beta-barrel domain-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
DAK1/DegV-like0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Histone-fold0Direct
alpha-D-mannose-specific plant lectins0Direct
PTS system IIB component-like0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
G protein-binding domain0Direct
Actin-like ATPase domain0Direct
Snake toxin-like0Direct
Retroviral matrix proteins0Direct
4'-phosphopantetheinyl transferase0Direct
Glycerate kinase I0Direct
Ribokinase-like0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
DhaL-like0Direct
Spectrin repeat0Direct
RNA polymerase subunits0Direct
RPB6/omega subunit-like0Direct
Soluble domain of poliovirus core protein 3a0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
HAMP domain-like0Direct
RBP11-like subunits of RNA polymerase0Direct
ACT-like0Direct
PAP/OAS1 substrate-binding domain0Direct
RNA polymerase subunit RPB100Direct
Glucose permease domain IIB0Direct
PIN domain-like0Direct
Polo-box domain0Direct
Doublecortin (DC)0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Nucleotidyltransferase0Direct
Fic-like0Direct
Plexin repeat0Direct
AF1104-like0Direct
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30Direct
Phoshotransferase/anion transport protein0Direct
Thiamin pyrophosphokinase, substrate-binding domain0Direct
Duplicated hybrid motif0Direct
ARM repeat0Direct
DBL homology domain (DH-domain)0Direct
NAD kinase/diacylglycerol kinase-like0Direct
Homodimeric domain of signal transducing histidine kinase0Direct
PTS IIb component0Direct
Trimeric LpxA-like enzymes0Direct
SufE/NifU0Direct
Poly(A) polymerase catalytic subunit-like0Direct
Retrovirus zinc finger-like domains0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
C-terminal domain of RNA polymerase alpha subunit0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
N-terminal Zn binding domain of HIV integrase0Direct
FAT domain of focal adhesion kinase0Direct
Guanido kinase N-terminal domain0Direct
L domain-like0Direct
PYP-like sensor domain (PAS domain)0Direct
Microbial and mitochondrial ADK, insert "zinc finger" domain0Direct
Thiamin pyrophosphokinase, catalytic domain0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Phospholipase D/nuclease0Direct
HR1 repeat0Direct
PsbU/PolX domain-like0Direct
DNA polymerase beta, N-terminal domain-like0Direct
BAR/IMD domain-like0Direct
Phosphofructokinase0Direct
Histidine-containing phosphotransfer domain, HPT domain0Direct
Regulator of G-protein signaling, RGS0Direct
CAD & PB1 domains0Direct
PK C-terminal domain-like0Direct
Trypsin-like serine proteases0Direct
Phosphoglycerate kinase0Direct
Ubiquitin-like0.000000000000002098Direct
GAF domain-like0.000000000004499Direct
Coronavirus NSP8-like0.00000000007297Direct
Coronavirus NSP7-like0.00000000007297Direct
Replicase NSP90.00000000007297Direct
Coronavirus NSP10-like0.00000000007297Direct
Second domain of FERM0.0000000005161Direct
EF-hand0.000000000715Direct
SMAD/FHA domain0.000000003753Direct
GckA/TtuD-like0.00000002541Direct
Hedgehog/intein (Hint) domain0.00000008607Direct
Ankyrin repeat0.000000156Direct
PX domain0.0000002012Direct
NSP3A-like0.0000002559Direct
HD-domain/PDEase-like0.000002263Direct
MIT domain0.000004617Direct
Quinoprotein alcohol dehydrogenase-like0.000006021Direct
DEATH domain0.00001148Direct
WD40 repeat-like0.00001421Direct
YWTD domain0.00002526Direct
Homing endonucleases0.00003349Direct
HIT-like0.00003856Direct
CRAL/TRIO domain0.00009554Direct
Nucleotidylyl transferase0.00009722Direct
CheY-like0.0001195Direct
NTF2-like0.0001235Direct
C-type lectin-like0.0001367Direct
beta-sandwich domain of Sec23/240.0002298Direct
IpsF-like0.0007786Direct
TPR-like0.001932Inherited
PDZ domain-like0.004965Inherited
Homeodomain-like0.009307Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.01403Inherited
CYTH-like phosphatases0.02011Inherited
Rubredoxin-like0.02789Inherited
Molybdenum cofactor biosynthesis proteins0.03042Inherited
cAMP-binding domain-like0.08072Inherited
Zinc beta-ribbon0.1236Inherited
Glutamine synthetase/guanido kinase0.1508Inherited
Nucleic acid-binding proteins0.1982Inherited
UBA-like0.2304Inherited
Macro domain-like0.4762Inherited
Ribonuclease Rh-like0.8065Inherited
Globin-like0.8304Inherited
MoeA N-terminal region -like0.882Inherited
MoeA C-terminal domain-like0.882Inherited
SAICAR synthase-like0.8903Inherited
Nucleotide cyclase0.8975Inherited
Kringle-like0.9404Inherited
beta-beta-alpha zinc fingers0.9502Inherited
PurM N-terminal domain-like0.9942Inherited
PurM C-terminal domain-like0.9975Inherited
Dihydropteroate synthetase-like1Inherited
EPT/RTPC-like1Inherited
E set domains1Inherited
ADP-ribosylation1Inherited
Thioredoxin-like1Inherited
Heme oxygenase-like1Inherited
Translation proteins1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
Aldolase1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Galactose-binding domain-like1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
FYVE/PHD zinc finger1Inherited
Phosphoglycerate mutase-like1Inherited
"Winged helix" DNA-binding domain1Inherited
DNase I-like1Inherited
RmlC-like cupins1Inherited
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain1Inherited
HAD-like1Inherited
Alkaline phosphatase-like1Inherited
Pyrimidine nucleoside phosphorylase C-terminal domain1Inherited
RNA-binding domain, RBD1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
BRCT domain1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
Class II aaRS and biotin synthetases1Inherited
Clavaminate synthase-like1Inherited
PRTase-like1Inherited
SIS domain1Inherited
TGS-like1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited
Dehydroquinate synthase-like1Inherited
dUTPase-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
ALDH-like1Inherited
Concanavalin A-like lectins/glucanases1Inherited


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Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
DnaQ-like 3'-5' exonuclease0Direct
N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system0Direct
Insert subdomain of RNA polymerase alpha subunit0Direct
Nsp15 C-terminal domain-like0Direct
PPK middle domain-like0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain0Direct
Pyruvate kinase0Direct
CoaX-like0Direct
Molybdenum cofactor biosynthesis protein MoeB0Direct
Class II viral fusion proteins C-terminal domain0Direct
AF1104-like0Direct
RBP11/RpoL0Direct
Sema domain0Direct
Homodimeric domain of signal transducing histidine kinase0Direct
N-acetyl-l-glutamate kinase0Direct
Kinase associated domain 1, KA10Direct
TBP-associated factors, TAFs0Direct
Spectrin repeat0Direct
ADP-specific Phosphofructokinase/Glucokinase0Direct
Thiamin biosynthesis kinases0Direct
Retrovirus zinc finger-like domains0Direct
Legume lectins0Direct
Holo-(acyl carrier protein) synthase ACPS0Direct
PTS IIb component0Direct
Receiver domain of the ethylene receptor0Direct
5' to 3' exonuclease catalytic domain0Direct
RIO1-like kinases0Direct
Plexin repeat0Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0Direct
Inositol polyphosphate kinase (IPK)0Direct
Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A0Direct
Retrovirus capsid protein C-terminal domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Phosphoglycerate kinase0Direct
UDP-glucose pyrophosphorylase0Direct
AF1531-like0Direct
Poly(A) polymerase, PAP, N-terminal domain0Direct
FAT domain of focal adhesion kinase0Direct
PAPS reductase-like0Direct
Protein kinases, catalytic subunit0Direct
Phosphoribulokinase/pantothenate kinase0Direct
Poly A polymerase C-terminal region-like0Direct
Adenylyltransferase0Direct
GHMP Kinase, N-terminal domain0Direct
Aspartokinase allosteric domain-like0Direct
Viral proteases0Direct
MarR-like transcriptional regulators0Direct
RNA helicase0Direct
DNA polymerase I0Direct
APH phosphotransferases0Direct
Poly(A) polymerase, PAP, middle domain0Direct
SP1160 C-terminal domain-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
RPB60Direct
Nucleoside diphosphate kinase, NDK0Direct
Growth factor receptor domain0Direct
Ribokinase-like0Direct
CTP-dependent riboflavin kinase-like0Direct
N-terminal Zn binding domain of HIV integrase0Direct
Chemotaxis protein CheA P1 domain0Direct
Tpt1/KptA0Direct
Fibronectin type III0Direct
Glycerol kinase0Direct
Regulator of chromosome condensation RCC10Direct
ATP sulfurylase C-terminal domain0Direct
RhoA-binding domain0Direct
PTS system, Lactose/Cellobiose specific IIB subunit0Direct
glucose-1-phosphate thymidylyltransferase0Direct
Doublecortin (DC)0Direct
DhaL-like0Direct
Archaeal tRNA CCA-adding enzyme substrate-binding domain0Direct
CheW-like0Direct
DNA polymerase beta, N-terminal domain-like0Direct
Phytochrome-specific domain0Direct
Immunodeficiency virus matrix proteins0Direct
FCH domain0Direct
mannose-1-phosphate guanylyl transferase0Direct
SH3-domain0Direct
HAMP domain0Direct
Pyruvate phosphate dikinase, C-terminal domain0Direct
Nsp15 N-terminal domain-like0Direct
Poly A polymerase head domain-like0Direct
PyrH-like0Direct
PB1 domain0Direct
C-terminal domain of RNA polymerase alpha subunit0Direct
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain0Direct
Sensory domain of two-component sensor kinase0Direct
DNA polymerase III clamp loader subunits, C-terminal domain0Direct
Fic-like0Direct
RpiR-like0Direct
Myosin rod fragments0Direct
RNA-polymerase beta-prime0Direct
Galactokinase0Direct
RNA polymerase subunit RPB100Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Pyruvate phosphate dikinase, central domain0Direct
Ephrin receptor ligand binding domain0Direct
DAK10Direct
RNA-dependent RNA-polymerase0Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
Regulator of G-protein signaling, RGS0Direct
Extracellular domain of cell surface receptors0Direct
Ribonuclease PH domain 2-like0Direct
RPB50Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
HTLV-II matrix protein0Direct
Flavivirus capsid protein C0Direct
DNA polymerase III, beta subunit0Direct
Glucose permease-like0Direct
Swapped Polo-box domain0Direct
Viral glycoprotein, central and dimerisation domains0Direct
alpha-D-mannose-specific plant lectins0Direct
SH2 domain0Direct
LuxQ-periplasmic domain-like0Direct
Type II thymidine kinase0Direct
RNA-polymerase beta0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Soluble domain of poliovirus core protein 3a0Direct
Mevalonate kinase0Direct
Discoidin domain (FA58C, coagulation factor 5/8 C-terminal domain)0Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
Thiamin pyrophosphokinase, substrate-binding domain0Direct
DNA polymerase beta-like0Direct
Glutamine synthase adenylyltransferase GlnE, domain 20Direct
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30Direct
Ras-binding domain, RBD0Direct
MHCK/EF2 kinase0Direct
Glycerate kinase I0Direct
DEATH domain, DD0Direct
Glucokinase0Direct
Flavin-binding PAS domain0Direct
Archaeal tRNA CCA-adding enzyme catalytic domain0Direct
Shikimate kinase (AroK)0Direct
V set domains (antibody variable domain-like)0Direct
alpha-ketoacid dehydrogenase kinase, C-terminal domain0Direct
PfkB-like kinase0Direct
SAM (sterile alpha motif) domain0Direct
Homoserine kinase0Direct
Gluconate kinase0Direct
NAD kinase-like0Direct
MogA-like0Direct
CheY-binding domain of CheA0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
Sporulation response regulatory protein Spo0B0Direct
Pleckstrin-homology domain (PH domain)0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Guanido kinase N-terminal domain0Direct
mRNA capping enzyme0Direct
Poly(A) polymerase, PAP, C-terminal domain0Direct
Retroviral protease (retropepsin)0Direct
Macro domain0Direct
Polygalacturonase inhibiting protein PGIP0Direct
Polo-box duplicated region0Direct
Phosphofructokinase0Direct
RWD domain0Direct
MM2497-like0Direct
Microbial and mitochondrial ADK, insert "zinc finger" domain0Direct
I set domains0Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0Direct
Reverse transcriptase0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Guanido kinase catalytic domain0Direct
Choline kinase0Direct
Cold shock DNA-binding domain-like0Direct
Ssp2 C-terminal domain-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
GlmU C-terminal domain-like0Direct
GlnE-like domain0Direct
Pyruvate phosphate dikinase, N-terminal domain0Direct
DNA polymerase beta-like, second domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Phosphoribosylpyrophosphate synthetase-like0Direct
HR1 repeat0Direct
Caliciviridae-like VP0Direct
Ribonuclease PH domain 1-like0Direct
L domain0Direct
KaiB-like0Direct
ATP-dependent riboflavin kinase-like0Direct
Fumble-like0Direct
Pyruvate kinase beta-barrel domain0Direct
LIM domain0Direct
Hexokinase0Direct
Acetokinase-like0Direct
Synaptotagmin-like (S variant)0Direct
Transcriptional factor domain0Direct
YWTD domain0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
ATP sulfurylase catalytic domain0Direct
Cytidylyltransferase0Direct
Polyphosphate kinase C-terminal domain0Direct
Poxvirus poly(A) polymerase catalytic subunit-like0Direct
Pyruvate kinase, C-terminal domain0Direct
T7 RNA polymerase0Direct
CofD-like0Direct
phosphatase domain of polynucleotide kinase0Direct
Histidine kinase0Direct
Diacylglycerol kinase-like0Direct
RNA polymerase alpha subunit dimerisation domain0Direct
Archaeal tRNA CCA-adding enzyme0Direct
Retroviral integrase, catalytic domain0Direct
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Type II thymidine kinase zinc finger0Direct
DBL homology domain (DH-domain)0Direct
MAST3 pre-PK domain-like0Direct
IIA domain of mannitol-specific and ntr phosphotransferase EII0Direct
PPK N-terminal domain-like0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Viral cysteine protease of trypsin fold0Direct
Adenosine-5'phosphosulfate kinase (APS kinase)0Direct
Hexose-1-phosphate uridylyltransferase0Direct
DNA-binding domain of retroviral integrase0Direct
Nucleotide and nucleoside kinases0Direct
RNA polymerase omega subunit0Direct
Thiamin pyrophosphokinase, catalytic domain0Direct
ATP sulfurylase N-terminal domain0Direct
Cytidylytransferase0Direct
Carbamate kinase0Direct
PTS system, Fructose specific IIB subunit-like0Direct
BphP N-terminal domain-like0Direct
HPr-like0Direct
4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE0Direct
ROK0Direct
Glucose permease domain IIB0Direct
Calmodulin-like3.476e-16Direct
PHP domain0.000000000000002408Direct
RelA/SpoT domain0.0000000000006749Direct
GGDEF domain0.000000000002149Direct
Coronavirus NSP8-like0.00000000003455Direct
Replicase NSP90.00000000003455Direct
Coronavirus NSP7-like0.00000000003455Direct
Coronavirus NSP10-like0.00000000003455Direct
Heme-binding PAS domain0.0000000002522Direct
mRNA cap methylase0.0000000002602Direct
Ngr ectodomain-like0.0000000008503Direct
FHA domain0.000000000854Direct
Second domain of FERM0.000000001167Direct
GckA/TtuD-like0.00000001625Direct
PX domain0.0000000189Direct
GAF domain0.00000008381Direct
NSP3A-like0.000000147Direct
MIT domain0.0000003528Direct
Ankyrin repeat0.000001055Direct
HD domain0.0000012Direct
Elongation factors0.000008446Direct
PLC-like (P variant)0.00001009Direct
BadF/BadG/BcrA/BcrD-like0.0001007Direct
IpsF-like0.0003451Direct
First domain of FERM0.0007549Direct
WD40-repeat0.0008349Direct
Probable phosphatase YrbI0.0009542Direct
Intein (protein splicing domain)0.001622Inherited
Third domain of FERM0.001923Inherited
Homoserine dehydrogenase-like0.002262Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.004123Inherited
TENA/THI-40.004961Inherited
Motor proteins0.009177Inherited
Quinoprotein alcohol dehydrogenase-like0.01462Inherited
cAMP-binding domain0.02255Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.02713Inherited
PDZ domain0.04118Inherited
EF-hand modules in multidomain proteins0.06467Inherited
AlkB-like0.1199Inherited
DHN aldolase/epimerase0.1985Inherited
CheY-related0.4482Inherited
Canonical RBD0.5032Inherited
Kringle modules0.6169Inherited
Ribonuclease Rh-like0.7324Inherited
MoeA C-terminal domain-like0.8042Inherited
MoeA N-terminal region -like0.8633Inherited
MoeA central domain-like0.8633Inherited
PurM N-terminal domain-like0.8679Inherited
PurM C-terminal domain-like0.8724Inherited
G proteins0.8901Inherited
Enolpyruvate transferase, EPT1Inherited
Ribonuclease H1Inherited
mRNA cap (Guanine N-7) methyltransferase1Inherited
Phosphoribosyltransferases (PRTases)1Inherited
dUTPase-like1Inherited
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain1Inherited
Pyrimidine nucleoside phosphorylase C-terminal domain1Inherited
Dihydropteroate synthetase1Inherited
Extended AAA-ATPase domain1Inherited
Dehydroquinate synthase, DHQS1Inherited
ALDH-like1Inherited
LplA-like1Inherited
mono-SIS domain1Inherited
Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain1Inherited
Aminoacid dehydrogenase-like, C-terminal domain1Inherited
DNA ligase/mRNA capping enzyme postcatalytic domain1Inherited
Shikimate dehydrogenase-like1Inherited
Class I aldolase1Inherited
Nitrogenase iron protein-like1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ARM repeat0Direct
GroEL apical domain-like0Direct
Regulator of G-protein signaling, RGS0Direct
SH3-domain0Direct
HR1 repeat0Direct
Glucose permease domain IIB0Direct
AF1531-like0Direct
Penicillin-binding protein 2x (pbp-2x), c-terminal domain0Direct
GHMP Kinase, C-terminal domain0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)0Direct
SAM/Pointed domain0Direct
PH domain-like0Direct
PK beta-barrel domain-like0Direct
TAF(II)230 TBP-binding fragment0Direct
N-terminal Zn binding domain of HIV integrase0Direct
RNA polymerase subunits0Direct
G protein-binding domain0Direct
4'-phosphopantetheinyl transferase0Direct
Plexin repeat0Direct
L27 domain0Direct
Ribonuclease H-like0Direct
BAR/IMD domain-like0Direct
RPB6/omega subunit-like0Direct
SufE/NifU0Direct
Trimeric LpxA-like enzymes0Direct
Phosphofructokinase0Direct
CheY-binding domain of CheA0Direct
Acid proteases0Direct
Doublecortin (DC)0Direct
PAP/Archaeal CCA-adding enzyme, C-terminal domain0Direct
Sensory domain-like0Direct
Cysteine-rich domain0Direct
Phosphoglycerate kinase0Direct
HAMP domain-like0Direct
Retroviral matrix proteins0Direct
C-terminal domain of RNA polymerase alpha subunit0Direct
PsbU/PolX domain-like0Direct
Soluble domain of poliovirus core protein 3a0Direct
CheW-like0Direct
RBP11-like subunits of RNA polymerase0Direct
MAST3 pre-PK domain-like0Direct
Retrovirus zinc finger-like domains0Direct
Nucleotide-diphospho-sugar transferases0Direct
Actin-like ATPase domain0Direct
DNA polymerase beta, N-terminal domain-like0Direct
Duplicated hybrid motif0Direct
Histidine-containing phosphotransfer domain, HPT domain0Direct
Snake toxin-like0Direct
Notch domain0Direct
Tricorn protease domain 20Direct
alpha-D-mannose-specific plant lectins0Direct
PYP-like sensor domain (PAS domain)0Direct
Immunoglobulin0Direct
GroEL-intermediate domain like0Direct
L domain-like0Direct
Sema domain0Direct
RNA polymerase subunit RPB100Direct
Histone-fold0Direct
DNA clamp0Direct
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 30Direct
PPK N-terminal domain-like0Direct
Protein kinase-like (PK-like)0Direct
PUA domain-like0Direct
DBL homology domain (DH-domain)0Direct
Poly(A) polymerase catalytic subunit-like0Direct
PK C-terminal domain-like0Direct
ACT-like0Direct
RNI-like0Direct
Thiamin pyrophosphokinase, substrate-binding domain0Direct
Nucleoside diphosphate kinase, NDK0Direct
Trypsin-like serine proteases0Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0Direct
Positive stranded ssRNA viruses0Direct
N-terminal, heterodimerisation domain of RBP7 (RpoE)0Direct
PHP14-like0Direct
alpha-ketoacid dehydrogenase kinase, N-terminal domain0Direct
Phoshotransferase/anion transport protein0Direct
DAK1/DegV-like0Direct
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0Direct
Phosphohistidine domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
DNA-binding domain of retroviral integrase0Direct
DNA polymerase III chi subunit0Direct
Flavivirus capsid protein C0Direct
Trm112p-like0Direct
Nucleotidyltransferase substrate binding subunit/domain0Direct
PIN domain-like0Direct
CAD & PB1 domains0Direct
Polo-box domain0Direct
RCC1/BLIP-II0Direct
Zinc finger domain of DNA polymerase-alpha0Direct
Cyclin-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
post-AAA+ oligomerization domain-like0Direct
Ribonuclease PH domain 2-like0Direct
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain0Direct
Ribokinase-like0Direct
DhaL-like0Direct
PTS-regulatory domain, PRD0Direct
Thiamin pyrophosphokinase, catalytic domain0Direct
Growth factor receptor domain0Direct
Riboflavin kinase-like0Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0Direct
Fibronectin type III0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
EndoU-like0Direct
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit0Direct
CofD-like0Direct
Retrovirus capsid protein, N-terminal core domain0Direct
Cadherin-like0Direct
Sporulation response regulatory protein Spo0B0Direct
Nucleotidyltransferase0Direct
FAT domain of focal adhesion kinase0Direct
PHP domain-like0Direct
PTS system IIB component-like0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0Direct
Viral leader polypeptide zinc finger0Direct
Insert subdomain of RNA polymerase alpha subunit0Direct
Eukaryotic type KH-domain (KH-domain type I)0Direct
Glycerate kinase I0Direct
Activating enzymes of the ubiquitin-like proteins0Direct
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0Direct
HPr-like0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Myosin rod fragments0Direct
Retrovirus capsid dimerization domain-like0Direct
Homodimeric domain of signal transducing histidine kinase0Direct
KA1-like0Direct
Spectrin repeat0Direct
PTS IIb component0Direct
Ribosomal protein S5 domain 2-like0Direct
NAD kinase/diacylglycerol kinase-like0Direct
PAP/OAS1 substrate-binding domain0Direct
Guanido kinase N-terminal domain0Direct
Microbial and mitochondrial ADK, insert "zinc finger" domain0Direct
AF1104-like0Direct
DNA/RNA polymerases0Direct
Phospholipase D/nuclease0Direct
Viral glycoprotein, central and dimerisation domains0Direct
SH2 domain0Direct
Carbamate kinase-like0Direct
Poly A polymerase C-terminal region-like0Direct
RPB5-like RNA polymerase subunit0Direct
Fic-like0Direct
Ubiquitin-like0.000000000000001741Direct
GAF domain-like0.000000000003934Direct
Coronavirus NSP8-like0.00000000006273Direct
Replicase NSP90.00000000006273Direct
Coronavirus NSP10-like0.00000000006273Direct
Coronavirus NSP7-like0.00000000006273Direct
Second domain of FERM0.0000000004381Direct
EF-hand0.0000000006739Direct
SMAD/FHA domain0.000000003192Direct
GckA/TtuD-like0.00000002123Direct
Hedgehog/intein (Hint) domain0.00000007536Direct
Ankyrin repeat0.0000001303Direct
PX domain0.0000001716Direct
NSP3A-like0.0000002213Direct
HD-domain/PDEase-like0.000002317Direct
MIT domain0.000003952Direct
Quinoprotein alcohol dehydrogenase-like0.000005263Direct
DEATH domain0.00001004Direct
WD40 repeat-like0.00001255Direct
YWTD domain0.00002154Direct
Homing endonucleases0.00002937Direct
CRAL/TRIO domain0.00008229Direct
NTF2-like0.0001104Direct
CheY-like0.0001138Direct
C-type lectin-like0.0001177Direct
Nucleotidylyl transferase0.0001423Direct
beta-sandwich domain of Sec23/240.0001967Direct
HIT-like0.0002497Direct
IpsF-like0.0008157Direct
TPR-like0.00178Inherited
SARS Nsp1-like0.004321Inherited
PDZ domain-like0.004541Inherited
Homeodomain-like0.008177Inherited
Chaperone J-domain0.008489Inherited
GTPase activation domain, GAP0.008489Inherited
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain0.01239Inherited
CYTH-like phosphatases0.01808Inherited
Rubredoxin-like0.02505Inherited
Molybdenum cofactor biosynthesis proteins0.02725Inherited
C-terminal domain of transcriptional repressors0.02987Inherited
HCP-like0.04849Inherited
cAMP-binding domain-like0.0743Inherited
Zinc beta-ribbon0.1139Inherited
Glutamine synthetase/guanido kinase0.1438Inherited
Nucleic acid-binding proteins0.2134Inherited
UBA-like0.3073Inherited
Macro domain-like0.4594Inherited
Ribonuclease Rh-like0.7625Inherited
Globin-like0.7859Inherited
MoeA N-terminal region -like0.8322Inherited
MoeA C-terminal domain-like0.8322Inherited
SAICAR synthase-like0.8514Inherited
Nucleotide cyclase0.8523Inherited
Kringle-like0.8904Inherited
beta-beta-alpha zinc fingers0.8978Inherited
PurM N-terminal domain-like0.9501Inherited
PurM C-terminal domain-like0.9533Inherited
RNA-binding domain, RBD0.9883Inherited
Heme oxygenase-like1Inherited
BRCT domain1Inherited
DNase I-like1Inherited
Dihydropteroate synthetase-like1Inherited
dUTPase-like1Inherited
RING/U-box1Inherited
Pyrimidine nucleoside phosphorylase C-terminal domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
PRTase-like1Inherited
DNA ligase/mRNA capping enzyme, catalytic domain1Inherited
ALDH-like1Inherited
Class II aaRS and biotin synthetases1Inherited
Aldolase1Inherited
Phosphoglycerate mutase-like1Inherited
Thiamin phosphate synthase1Inherited
UDP-Glycosyltransferase/glycogen phosphorylase1Inherited
Thioredoxin-like1Inherited
Phosphoglucomutase, first 3 domains1Inherited
Dehydroquinate synthase-like1Inherited
Alkaline phosphatase-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain1Inherited
lambda repressor-like DNA-binding domains1Inherited
HAD-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Translation proteins1Inherited
TGS-like1Inherited
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain1Inherited
E set domains1Inherited
EPT/RTPC-like1Inherited
SIS domain1Inherited
(Phosphotyrosine protein) phosphatases II1Inherited
FYVE/PHD zinc finger1Inherited
Concanavalin A-like lectins/glucanases1Inherited
SGNH hydrolase1Inherited
Bromodomain1Inherited
Clavaminate synthase-like1Inherited
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain1Inherited
Galactose-binding domain-like1Inherited
Phosphoenolpyruvate/pyruvate domain1Inherited
RmlC-like cupins1Inherited
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase1Inherited
Adenine nucleotide alpha hydrolases-like1Inherited
Phosphoglucomutase, C-terminal domain1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
ADP-ribosylation1Inherited
"Winged helix" DNA-binding domain1Inherited
Cysteine proteinases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63520,63520
  • 63520 - PTS-regulatory domain, PRD
  • 63520 - PTS-regulatory domain, PRD
  • 0Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0Direct
    47353,57756
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    47473,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0Direct
    46585,49562
  • 46585 - HR1 repeat
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    103190,158472
  • 103190 - Sensory domain-like
  • 158472 - HAMP domain-like
  • 0Direct
    82615,82615
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    53098,53098
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    56672,90234
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0Direct
    56112,50978
  • 56112 - Protein kinase-like (PK-like)
  • 50978 - WD40 repeat-like
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56112,48403
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    81301,81891
  • 81301 - Nucleotidyltransferase
  • 81891 - Poly A polymerase C-terminal region-like
  • 0Direct
    55205,52540
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,56112
  • 49899 - Concanavalin A-like lectins/glucanases
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    46689,53697
  • 46689 - Homeodomain-like
  • 53697 - SIS domain
  • 0Direct
    53067,56112
  • 53067 - Actin-like ATPase domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48452,140931
  • 48452 - TPR-like
  • 140931 - Fic-like
  • 0Direct
    53633,55021
  • 53633 - Carbamate kinase-like
  • 55021 - ACT-like
  • 0Direct
    64484,64484
  • 64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
  • 64484 - beta and beta-prime subunits of DNA dependent RNA-polymerase
  • 0Direct
    55890,55874
  • 55890 - Sporulation response regulatory protein Spo0B
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    55681,82649
  • 55681 - Class II aaRS and biotin synthetases
  • 82649 - SufE/NifU
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    56112,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 0Direct
    57756,50630
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    56672,51294
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0Direct
    54197,54197
  • 54197 - HIT-like
  • 54197 - HIT-like
  • 0Direct
    47986,56112
  • 47986 - DEATH domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54593,53784
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 53784 - Phosphofructokinase
  • 0Direct
    52047,56112
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    55083,51717
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    56553,55257
  • 56553 - Insert subdomain of RNA polymerase alpha subunit
  • 55257 - RBP11-like subunits of RNA polymerase
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    55257,47789
  • 55257 - RBP11-like subunits of RNA polymerase
  • 47789 - C-terminal domain of RNA polymerase alpha subunit
  • 0Direct
    64268,49562
  • 64268 - PX domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    116846,116846
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0Direct
    140356,143724
  • 140356 - PPK N-terminal domain-like
  • 143724 - PHP14-like
  • 0Direct
    52540,88697
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 88697 - PUA domain-like
  • 0Direct
    56219,56672
  • 56219 - DNase I-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55874,50341
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 50341 - CheW-like
  • 0Direct
    52540,53254
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53254 - Phosphoglycerate mutase-like
  • 0Direct
    50998,56112
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    51391,53613
  • 51391 - Thiamin phosphate synthase
  • 53613 - Ribokinase-like
  • 0Direct
    50249,56300
  • 50249 - Nucleic acid-binding proteins
  • 56300 - Metallo-dependent phosphatases
  • 0Direct
    55608,56672
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    158472,47384
  • 158472 - HAMP domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    82549,101473
  • 82549 - DAK1/DegV-like
  • 101473 - DhaL-like
  • 0Direct
    53448,51182
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51182 - RmlC-like cupins
  • 0Direct
    88697,52374
  • 88697 - PUA domain-like
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    51569,53223
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    46915,54211
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    46785,82114
  • 46785 - "Winged helix" DNA-binding domain
  • 82114 - Riboflavin kinase-like
  • 0Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    57667,54928
  • 57667 - beta-beta-alpha zinc fingers
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    49562,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,57774
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
  • 0Direct
    55785,55781
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55781 - GAF domain-like
  • 0Direct
    47391,52540
  • 47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47384,55874
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    51735,52540
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    82185,82185
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
  • 0Direct
    55781,47384
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    52540,51569
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    52540,47648
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 0Direct
    48097,56112
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,103243
  • 56112 - Protein kinase-like (PK-like)
  • 103243 - KA1-like
  • 0Direct
    52540,57802
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57802 - Rubredoxin-like
  • 0Direct
    47943,47353
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    50465,52540
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    57889,111331
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    50249,89550
  • 50249 - Nucleic acid-binding proteins
  • 89550 - PHP domain-like
  • 0Direct
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    55931,48034
  • 55931 - Glutamine synthetase/guanido kinase
  • 48034 - Guanido kinase N-terminal domain
  • 0Direct
    50156,50044
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    55979,55979
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 0Direct
    51621,52935
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    63999,63862
  • 63999 - Thiamin pyrophosphokinase, catalytic domain
  • 63862 - Thiamin pyrophosphokinase, substrate-binding domain
  • 0Direct
    53448,52266
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 52266 - SGNH hydrolase
  • 0Direct
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53448,51161
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 51161 - Trimeric LpxA-like enzymes
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    55785,47384
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    52374,52540
  • 52374 - Nucleotidylyl transferase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57850,48371
  • 57850 - RING/U-box
  • 48371 - ARM repeat
  • 0Direct
    69012,55874
  • 69012 - alpha-ketoacid dehydrogenase kinase, N-terminal domain
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    53633,53720
  • 53633 - Carbamate kinase-like
  • 53720 - ALDH-like
  • 0Direct
    54919,54919
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 54919 - Nucleoside diphosphate kinase, NDK
  • 0Direct
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0Direct
    55052,47384
  • 55052 - CheY-binding domain of CheA
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    55781,55785
  • 55781 - GAF domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    88723,47807
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 0Direct
    52087,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 0Direct
    53613,48613
  • 53613 - Ribokinase-like
  • 48613 - Heme oxygenase-like
  • 0Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47226,55052
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 55052 - CheY-binding domain of CheA
  • 0Direct
    53448,69765
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 69765 - IpsF-like
  • 0Direct
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,53271
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 53271 - PRTase-like
  • 0Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    56112,55681
  • 56112 - Protein kinase-like (PK-like)
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52935,52009
  • 52935 - PK C-terminal domain-like
  • 52009 - Phosphohistidine domain
  • 0Direct
    103575,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    53271,53271
  • 53271 - PRTase-like
  • 53271 - PRTase-like
  • 0Direct
    51621,55804
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 55804 - Phoshotransferase/anion transport protein
  • 0Direct
    53098,46919
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    55073,56112
  • 55073 - Nucleotide cyclase
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54211,55666
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0Direct
    56672,55608
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 0Direct
    47831,52009
  • 47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
  • 52009 - Phosphohistidine domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    52113,47802
  • 52113 - BRCT domain
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 0Direct
    101288,50156
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    64268,56112
  • 64268 - PX domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53448,56784
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 56784 - HAD-like
  • 0Direct
    50729,55550
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0Direct
    56112,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 0Direct
    81593,81891
  • 81593 - Nucleotidyltransferase substrate binding subunit/domain
  • 81891 - Poly A polymerase C-terminal region-like
  • 0Direct
    57440,56112
  • 57440 - Kringle-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    47807,56672
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54277,56112
  • 54277 - CAD & PB1 domains
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    81631,55003
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    52799,56091
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0Direct
    52009,51621
  • 52009 - Phosphohistidine domain
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0Direct
    53633,88697
  • 53633 - Carbamate kinase-like
  • 88697 - PUA domain-like
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    47802,81585
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 0Direct
    56112,90257
  • 56112 - Protein kinase-like (PK-like)
  • 90257 - Myosin rod fragments
  • 0Direct
    55594,47831
  • 55594 - HPr-like
  • 47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
  • 0Direct
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,54928
  • 56112 - Protein kinase-like (PK-like)
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    52374,82114
  • 52374 - Nucleotidylyl transferase
  • 82114 - Riboflavin kinase-like
  • 0Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    101288,101288
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0Direct
    46785,56112
  • 46785 - "Winged helix" DNA-binding domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    52833,47384
  • 52833 - Thioredoxin-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    47807,53098
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 0Direct
    54277,57889
  • 54277 - CAD & PB1 domains
  • 57889 - Cysteine-rich domain
  • 0Direct
    49265,56112
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52172,52172
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0Direct
    56112,54427
  • 56112 - Protein kinase-like (PK-like)
  • 54427 - NTF2-like
  • 0Direct
    56112,64268
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 0Direct
    81891,109604
  • 81891 - Poly A polymerase C-terminal region-like
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0Direct
    56112,50985
  • 56112 - Protein kinase-like (PK-like)
  • 50985 - RCC1/BLIP-II
  • 0Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    50729,69322
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0Direct
    56112,50729
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0Direct
    52540,81301
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 81301 - Nucleotidyltransferase
  • 0Direct
    103190,55785
  • 103190 - Sensory domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48034,55931
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0Direct
    56112,52540
  • 56112 - Protein kinase-like (PK-like)
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55781,55874
  • 55781 - GAF domain-like
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    53850,55785
  • 53850 - Periplasmic binding protein-like II
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    56024,56024
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    56059,52009
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52009 - Phosphohistidine domain
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    56112,48452
  • 56112 - Protein kinase-like (PK-like)
  • 48452 - TPR-like
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55785,55890
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 0Direct
    56112,50044
  • 56112 - Protein kinase-like (PK-like)
  • 50044 - SH3-domain
  • 0Direct
    55804,52794
  • 55804 - Phoshotransferase/anion transport protein
  • 52794 - PTS system IIB component-like
  • 0Direct
    143724,56024
  • 143724 - PHP14-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50044,52540
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    50156,56112
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    63520,52794
  • 63520 - PTS-regulatory domain, PRD
  • 52794 - PTS system IIB component-like
  • 0Direct
    52794,52794
  • 52794 - PTS system IIB component-like
  • 52794 - PTS system IIB component-like
  • 0Direct
    103190,47384
  • 103190 - Sensory domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    50800,51621
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0Direct
    88798,50249
  • 88798 - N-terminal, heterodimerisation domain of RBP7 (RpoE)
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
  • 0Direct
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 0Direct
    54791,50249
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    53784,53784
  • 53784 - Phosphofructokinase
  • 53784 - Phosphofructokinase
  • 0Direct
    55666,46915
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0Direct
    55021,55021
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 0Direct
    51294,56672
  • 51294 - Hedgehog/intein (Hint) domain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    81301,81593
  • 81301 - Nucleotidyltransferase
  • 81593 - Nucleotidyltransferase substrate binding subunit/domain
  • 0Direct
    49265,63825
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56784,52540
  • 56784 - HAD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52058,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    89550,53098
  • 89550 - PHP domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    47836,47943
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 0Direct
    56112,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 0Direct
    55874,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 0Direct
    55666,54791
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    57774,52540
  • 57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55604,51261
  • 55604 - Glucose permease domain IIB
  • 51261 - Duplicated hybrid motif
  • 0Direct
    57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    56112,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0Direct
    52540,57716
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    52172,47226
  • 52172 - CheY-like
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 0Direct
    52794,55804
  • 52794 - PTS system IIB component-like
  • 55804 - Phoshotransferase/anion transport protein
  • 0Direct
    63825,49265
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 0Direct
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    50044,56112
  • 50044 - SH3-domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    81631,57756
  • 81631 - PAP/OAS1 substrate-binding domain
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    55021,51735
  • 55021 - ACT-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    50037,53067
  • 50037 - C-terminal domain of transcriptional repressors
  • 53067 - Actin-like ATPase domain
  • 0Direct
    55154,56091
  • 55154 - CYTH-like phosphatases
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 0Direct
    56796,55205
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 0Direct
    81585,81301
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0Direct
    109604,55021
  • 109604 - HD-domain/PDEase-like
  • 55021 - ACT-like
  • 0Direct
    52949,52540
  • 52949 - Macro domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81995,56112
  • 81995 - beta-sandwich domain of Sec23/24
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57889,50729
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 0Direct
    53756,53067
  • 53756 - UDP-Glycosyltransferase/glycogen phosphorylase
  • 53067 - Actin-like ATPase domain
  • 0Direct
    158472,55785
  • 158472 - HAMP domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 8.731e-16Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00000000000004503Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0000000000005314Direct
    81301,81271
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000000000002365Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.00000000001591Direct
    109604,81301
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 0.00000000002432Direct
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.00000000005434Direct
    51206,56112
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000000005434Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0.00000000006273Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0.00000000006273Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0.00000000006273Direct
    52058,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 0.00000000007904Direct
    52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0.0000000007313Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000001644Direct
    52374,52374
  • 52374 - Nucleotidylyl transferase
  • 52374 - Nucleotidylyl transferase
  • 0.00000322Direct
    51197,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000003893Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.00001883Direct
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0.0001232Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.0001747Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000419Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.000465Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0.0006587Direct
    57184,57184
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0.0007618Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.001884Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.002323Inherited
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.003269Inherited
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.003269Inherited
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0.004321Inherited
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.008489Inherited
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.01808Inherited
    55681,50037
  • 55681 - Class II aaRS and biotin synthetases
  • 50037 - C-terminal domain of transcriptional repressors
  • 0.02987Inherited
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0.0755Inherited
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.1558Inherited
    57783,57783
  • 57783 - Zinc beta-ribbon
  • 57783 - Zinc beta-ribbon
  • 0.3517Inherited
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0.3985Inherited
    55781,55781
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0.5194Inherited
    53218,63867
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.8322Inherited
    63882,53218
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 0.8322Inherited
    55620,55620
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 0.8422Inherited
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0.9468Inherited
    52418,54680
  • 52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
  • 54680 - Pyrimidine nucleoside phosphorylase C-terminal domain
  • 1Inherited
    47648,52418
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
  • 1Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 1Inherited
    56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 1Inherited
    51735,55347
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 1Inherited
    53633,55729
  • 53633 - Carbamate kinase-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 1Inherited
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 1Inherited
    53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    56112,101288,101288
  • 56112 - Protein kinase-like (PK-like)
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 0Direct
    52087,46966,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    57889,57889,111331
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 111331 - NAD kinase/diacylglycerol kinase-like
  • 0Direct
    55785,55890,55874
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    48726,49265,56112
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56796,55205,52540
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    52058,52058,56112
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,57184,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 57184 - Growth factor receptor domain
  • 0Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    158472,55785,47384
  • 158472 - HAMP domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    52949,52540,52540
  • 52949 - Macro domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0Direct
    88723,47807,56672
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52047,52047,52058
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0Direct
    53098,56672,51294
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    53098,46919,53098
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    50800,51621,52935
  • 50800 - PK beta-barrel domain-like
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    53850,53850,55785
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    57756,50630,56672
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52833,47384,55874
  • 52833 - Thioredoxin-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    55979,55979,55979
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 55979 - DNA clamp
  • 0Direct
    101912,103575,81296
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 0Direct
    54211,55666,54791
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 0Direct
    47384,55874,52172
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 0Direct
    55594,47831,52009
  • 55594 - HPr-like
  • 47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
  • 52009 - Phosphohistidine domain
  • 0Direct
    51294,56672,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 0Direct
    103190,47384,55874
  • 103190 - Sensory domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    55681,50037,53067
  • 55681 - Class II aaRS and biotin synthetases
  • 50037 - C-terminal domain of transcriptional repressors
  • 53067 - Actin-like ATPase domain
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    47031,50729,56112
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53850,55785,47384
  • 53850 - Periplasmic binding protein-like II
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    47226,55052,47384
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 55052 - CheY-binding domain of CheA
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    55874,52172,52172
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 52172 - CheY-like
  • 0Direct
    55608,56672,51294
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    51197,52540,56672
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    53098,56672,90234
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 90234 - Zinc finger domain of DNA polymerase-alpha
  • 0Direct
    101288,101288,50156
  • 101288 - L27 domain
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 0Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    47802,81585,81301
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 81301 - Nucleotidyltransferase
  • 0Direct
    47836,47943,47353
  • 47836 - Retroviral matrix proteins
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 0Direct
    46585,46585,46585
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 46585 - HR1 repeat
  • 0Direct
    140356,143724,56024
  • 140356 - PPK N-terminal domain-like
  • 143724 - PHP14-like
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    56112,64268,49562
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50447,50465,52540
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55781,55781,47384
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    52113,47802,81585
  • 52113 - BRCT domain
  • 47802 - DNA polymerase beta, N-terminal domain-like
  • 81585 - PsbU/PolX domain-like
  • 0Direct
    52540,52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    47831,52009,51621
  • 47831 - Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
  • 52009 - Phosphohistidine domain
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0Direct
    52540,57774,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0Direct
    57184,52058,49265
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 0Direct
    103190,158472,55785
  • 103190 - Sensory domain-like
  • 158472 - HAMP domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    56553,55257,47789
  • 56553 - Insert subdomain of RNA polymerase alpha subunit
  • 55257 - RBP11-like subunits of RNA polymerase
  • 47789 - C-terminal domain of RNA polymerase alpha subunit
  • 0Direct
    103575,81296,81296
  • 103575 - Plexin repeat
  • 81296 - E set domains
  • 81296 - E set domains
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    55620,55083,51717
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    47943,47353,57756
  • 47943 - Retrovirus capsid protein, N-terminal core domain
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    47031,50729,55550
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 0Direct
    52540,47648,52418
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
  • 0Direct
    47384,55874,50341
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 50341 - CheW-like
  • 0Direct
    55666,54791,50249
  • 55666 - Ribonuclease PH domain 2-like
  • 54791 - Eukaryotic type KH-domain (KH-domain type I)
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    55666,46915,54211
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55785,55785,47384
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 0Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    56672,53098,46919
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0Direct
    88697,52374,52540
  • 88697 - PUA domain-like
  • 52374 - Nucleotidylyl transferase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    56672,53098,50122
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0Direct
    51569,53223,51735
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53633,55021,55021
  • 53633 - Carbamate kinase-like
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    55874,52172,47226
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 52172 - CheY-like
  • 47226 - Histidine-containing phosphotransfer domain, HPT domain
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    55785,55781,55781
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55781 - GAF domain-like
  • 55781 - GAF domain-like
  • 0Direct
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    57774,52540,57774
  • 57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57774 - Microbial and mitochondrial ADK, insert "zinc finger" domain
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    54593,53784,53784
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 53784 - Phosphofructokinase
  • 53784 - Phosphofructokinase
  • 0Direct
    50156,50044,52540
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51621,52935,52009
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 52935 - PK C-terminal domain-like
  • 52009 - Phosphohistidine domain
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    57889,49562,56112
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52047,52047,56112
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    81301,81593,81891
  • 81301 - Nucleotidyltransferase
  • 81593 - Nucleotidyltransferase substrate binding subunit/domain
  • 81891 - Poly A polymerase C-terminal region-like
  • 0Direct
    52949,52540,56672
  • 52949 - Macro domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55205,52540,51569
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    55620,55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    49265,56112,48726
  • 49265 - Fibronectin type III
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 0Direct
    57889,50729,69322
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    55785,47384,55874
  • 55785 - PYP-like sensor domain (PAS domain)
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    55931,48034,55931
  • 55931 - Glutamine synthetase/guanido kinase
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0Direct
    55785,55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    47391,52540,52540
  • 47391 - Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    47353,57756,50630
  • 47353 - Retrovirus capsid dimerization domain-like
  • 57756 - Retrovirus zinc finger-like domains
  • 50630 - Acid proteases
  • 0Direct
    63825,49265,63825
  • 63825 - YWTD domain
  • 49265 - Fibronectin type III
  • 63825 - YWTD domain
  • 0Direct
    47807,53098,56672
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    55052,47384,55874
  • 55052 - CheY-binding domain of CheA
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    54211,55666,46915
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 0Direct
    48034,55931,48034
  • 48034 - Guanido kinase N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 48034 - Guanido kinase N-terminal domain
  • 0Direct
    103190,55785,55890
  • 103190 - Sensory domain-like
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55890 - Sporulation response regulatory protein Spo0B
  • 0Direct
    55781,47384,55874
  • 55781 - GAF domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    81301,81631,57756
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    52009,51621,55804
  • 52009 - Phosphohistidine domain
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 55804 - Phoshotransferase/anion transport protein
  • 0Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    81891,109604,55021
  • 81891 - Poly A polymerase C-terminal region-like
  • 109604 - HD-domain/PDEase-like
  • 55021 - ACT-like
  • 0Direct
    52058,52047,56112
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,51569,53223
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    48371,56112,64268
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 64268 - PX domain
  • 0Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    63520,52794,55804
  • 63520 - PTS-regulatory domain, PRD
  • 52794 - PTS system IIB component-like
  • 55804 - Phoshotransferase/anion transport protein
  • 0Direct
    143724,56024,56024
  • 143724 - PHP14-like
  • 56024 - Phospholipase D/nuclease
  • 56024 - Phospholipase D/nuclease
  • 0Direct
    56112,48403,52540
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    101288,50156,50044
  • 101288 - L27 domain
  • 50156 - PDZ domain-like
  • 50044 - SH3-domain
  • 0Direct
    55021,55021,51735
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    50044,55550,56112
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52540,88697,52374
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 88697 - PUA domain-like
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0Direct
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52799,56091,50249
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0Direct
    63520,63520,52794
  • 63520 - PTS-regulatory domain, PRD
  • 63520 - PTS-regulatory domain, PRD
  • 52794 - PTS system IIB component-like
  • 0Direct
    50249,89550,53098
  • 50249 - Nucleic acid-binding proteins
  • 89550 - PHP domain-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52047,52058,56112
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    109604,55021,55021
  • 109604 - HD-domain/PDEase-like
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 0Direct
    81301,81631,55003
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 55003 - PAP/Archaeal CCA-adding enzyme, C-terminal domain
  • 0Direct
    88723,47807,53098
  • 88723 - PIN domain-like
  • 47807 - 5' to 3' exonuclease, C-terminal subdomain
  • 53098 - Ribonuclease H-like
  • 0Direct
    56672,53098,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 53098 - Ribonuclease H-like
  • 0Direct
    50729,50044,55550
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0Direct
    48097,56112,50729
  • 48097 - Regulator of G-protein signaling, RGS
  • 56112 - Protein kinase-like (PK-like)
  • 50729 - PH domain-like
  • 0Direct
    47473,57889,57889
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    53850,53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,82615,82615
  • 56112 - Protein kinase-like (PK-like)
  • 82615 - Polo-box domain
  • 82615 - Polo-box domain
  • 0Direct
    47473,47473,57889
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 57889 - Cysteine-rich domain
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0Direct
    56059,52009,51621
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52009 - Phosphohistidine domain
  • 51621 - Phosphoenolpyruvate/pyruvate domain
  • 0Direct
    50037,53067,53067
  • 50037 - C-terminal domain of transcriptional repressors
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    56672,55608,56672
  • 56672 - DNA/RNA polymerases
  • 55608 - Homing endonucleases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    158472,47384,55874
  • 158472 - HAMP domain-like
  • 47384 - Homodimeric domain of signal transducing histidine kinase
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 0Direct
    46915,54211,55666
  • 46915 - Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55666 - Ribonuclease PH domain 2-like
  • 0Direct
    50729,57889,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    52058,49265,49265
  • 52058 - L domain-like
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0Direct
    56112,116846,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0Direct
    57716,50156,56112
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    55021,51735,55347
  • 55021 - ACT-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 55347 - Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
  • 0Direct
    109604,81301,81271
  • 109604 - HD-domain/PDEase-like
  • 81301 - Nucleotidyltransferase
  • 81271 - TGS-like
  • 0.000000000002365Direct
    51206,51206,56112
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.00000000005434Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0.00000000006273Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0.00000000006273Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0000000001045Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000000003882Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.00001987Direct
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0.0001232Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.002323Inherited
    48726,49265,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.003782Inherited
    63882,53218,63867
  • 63882 - MoeA N-terminal region -like
  • 53218 - Molybdenum cofactor biosynthesis proteins
  • 63867 - MoeA C-terminal domain-like
  • 0.8322Inherited
    53738,53738,55957
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 55957 - Phosphoglucomutase, C-terminal domain
  • 1Inherited
    53738,53738,53738
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 53738 - Phosphoglucomutase, first 3 domains
  • 1Inherited
    47648,52418,54680
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
  • 54680 - Pyrimidine nucleoside phosphorylase C-terminal domain
  • 1Inherited


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