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Acting on acid anhydrides

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   root [root] <6>
+ 1:   Hydrolases [3] <13>(329|528) (368|389|207)
0:   Acting on acid anhydrides [3.6] <5>(83|103) (94|93|62)
- 1:   In phosphorous-containing anhydrides [3.6.1] <67>(35|44) (40|33|19)
- 1:   Acting on acid anhydrides; catalyzing transmembran [3.6.3] <54>(12|12) (13|17|12)
- 1:   Acting on acid anhydrides; involved in cellular an [3.6.4] <13>(46|55) (51|47|29)
- 1:   Acting on GTP; involved in cellular and subcellula [3.6.5] <7>(4|4) (4|4|3)
- 1:   In sulfonyl-containing anhydrides [3.6.2] <2>(0|0) (0|0|0)


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Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
RuvA domain 2-like0Direct
DNA/RNA polymerases0Direct
Restriction endonuclease-like0Direct
Calcium ATPase, transmembrane domain M0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
BRK domain-like0Direct
Translation proteins0Direct
ABC transporter transmembrane region0Direct
Cdc48 domain 2-like0Direct
Flavivirus capsid protein C0Direct
Sec63 N-terminal domain-like0Direct
HIT-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Calcium ATPase, transduction domain A0Direct
Positive stranded ssRNA viruses0Direct
all-alpha NTP pyrophosphatases0Direct
"Winged helix" DNA-binding domain0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
EndoU-like0Direct
C-terminal domain of Ku800Direct
HAD-like0Direct
Origin of replication-binding domain, RBD-like0Direct
Rap30/74 interaction domains0Direct
EF-G C-terminal domain-like0Direct
Metallo-dependent phosphatases0Direct
Inorganic pyrophosphatase0Direct
HMA, heavy metal-associated domain0Direct
Soluble domain of poliovirus core protein 3a0Direct
DHH phosphoesterases0Direct
MOP-like0Direct
N-terminal domain of DnaB helicase0Direct
Nucleic acid-binding proteins0Direct
Nudix0Direct
dUTPase-like0Direct
ITPase-like0Direct
Acylphosphatase/BLUF domain-like0Direct
SPOC domain-like0Direct
Tudor/PWWP/MBT0.0000000000008956Direct
Chromo domain-like0.000000000001708Direct
SAP domain0.00000000002257Direct
Hedgehog/intein (Hint) domain0.00000000002567Direct
Viral glycoprotein, central and dimerisation domains0.0000000004925Direct
vWA-like0.000000001101Direct
Homing endonucleases0.000000003686Direct
Prokaryotic type I DNA topoisomerase0.000005958Direct
Coronavirus NSP8-like0.00002631Direct
Coronavirus NSP7-like0.00002631Direct
Replicase NSP90.00002631Direct
Coronavirus NSP10-like0.00002631Direct
MIT domain0.00003161Direct
E set domains0.0003008Direct
HRDC-like0.0005332Direct
Somatomedin B domain0.001225Inherited
NSP3A-like0.001329Inherited
WW domain0.003595Inherited
FYVE/PHD zinc finger0.008364Inherited
RNA-binding domain, RBD0.01123Inherited
His-Me finger endonucleases0.0196Inherited
R3H domain0.03241Inherited
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.1955Inherited
Trypsin-like serine proteases0.2689Inherited
CYTH-like phosphatases0.3199Inherited
Ankyrin repeat0.4016Inherited
HD-domain/PDEase-like0.7809Inherited
UBA-like0.8024Inherited
Clavaminate synthase-like0.8245Inherited
PH domain-like1Inherited
DNA-binding domain of retroviral integrase1Inherited
HisI-like1Inherited
Macro domain-like1Inherited
Acid proteases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Alkaline phosphatase-like1Inherited
Actin-like ATPase domain1Inherited
Ribonuclease Rh-like1Inherited
ADC-like1Inherited
SurE-like1Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase1Inherited
Retrovirus zinc finger-like domains1Inherited
N-terminal Zn binding domain of HIV integrase1Inherited
Concanavalin A-like lectins/glucanases1Inherited


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Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Nsp15 C-terminal domain-like0Direct
Manganese-dependent inorganic pyrophosphatase (family II)0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
ABC transporter transmembrane region0Direct
MutT-like0Direct
NADH pyrophosphatase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
Meta-cation ATPase, catalytic domain P0Direct
DNA helicase RuvA subunit, N-terminal domain0Direct
Inorganic pyrophosphatase0Direct
G proteins0Direct
ABC transporter ATPase domain-like0Direct
Replication initiation protein E10Direct
ABC-transporter additional domain0Direct
RNA helicase0Direct
dUTPase-like0Direct
Chromo domain0Direct
Acylphosphatase-like0Direct
DNA-binding domain from rap300Direct
Helicase-like "domain" of reverse gyrase0Direct
Sec63 N-terminal domain0Direct
RecA protein-like (ATPase-domain)0Direct
C-terminal domain of Ku800Direct
Tandem AAA-ATPase domain0Direct
Ku70 subunit middle domain0Direct
DNA helicase RuvA subunit, middle domain0Direct
Ku80 subunit N-terminal domain0Direct
Nsp15 N-terminal domain-like0Direct
HRDC domain from helicases0Direct
Ppx associated domain0Direct
RecQ helicase DNA-binding domain-like0Direct
RNA-dependent RNA-polymerase0Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
EF-G/eEF-2 domains III and V0Direct
Flavivirus capsid protein C0Direct
HMA, heavy metal-associated domain0Direct
Elongation factors0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Soluble domain of poliovirus core protein 3a0Direct
HisE-like (PRA-PH)0Direct
Extended AAA-ATPase domain0Direct
Calcium ATPase, transduction domain A0Direct
Ppx/GppA phosphatase0Direct
ITPase (Ham1)0Direct
Helicase DNA-binding domain0Direct
Sec63 C-terminal domain-like0Direct
Macro domain0Direct
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain0Direct
Caliciviridae-like VP0Direct
GUCT domain0Direct
ADPRibase-Mn-like0Direct
Rap30/74 interaction domains0Direct
RecG "wedge" domain0Direct
Ku80 subunit middle domain0Direct
Cdc48 domain 2-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
CDH-like0Direct
BRK domain-like0Direct
Viral cysteine protease of trypsin fold0Direct
Calcium ATPase, transmembrane domain M0Direct
mRNA cap methylase0Direct
N-terminal domain of DnaB helicase0Direct
Ku70 subunit N-terminal domain0Direct
Cdc48 N-terminal domain-like0Direct
Viral proteases6.929e-16Direct
Tudor domain0.0000000000002646Direct
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0.0000000000008982Direct
SPRY domain0.000000000009168Direct
SAP domain0.00000000001616Direct
Viral glycoprotein, central and dimerisation domains0.0000000002469Direct
Class II viral fusion proteins C-terminal domain0.000000000571Direct
Intein (protein splicing domain)0.00000002192Direct
CYTH domain0.00000006285Direct
Prokaryotic type I DNA topoisomerase0.000004434Direct
Coronavirus NSP8-like0.00001669Direct
Replicase NSP90.00001669Direct
Coronavirus NSP7-like0.00001669Direct
Coronavirus NSP10-like0.00001669Direct
AlkB-like0.000136Direct
Somatomedin B domain0.0009325Direct
NSP3A-like0.0009445Direct
WW domain0.002948Inherited
R3H domain0.02634Inherited
PHD domain0.07112Inherited
NagD-like0.1312Inherited
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0.1653Inherited
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.1653Inherited
Protein serine/threonine phosphatase0.2849Inherited
Ankyrin repeat0.3544Inherited
Pleckstrin-homology domain (PH domain)0.4013Inherited
beta-Phosphoglucomutase-like0.9857Inherited
Retrovirus zinc finger-like domains1Inherited
N-terminal Zn binding domain of HIV integrase1Inherited
SurE-like1Inherited
Retroviral protease (retropepsin)1Inherited
Reverse transcriptase1Inherited
L-histidinol dehydrogenase HisD1Inherited
Nitrogenase iron protein-like1Inherited
Retroviral integrase, catalytic domain1Inherited
Ribonuclease Rh-like1Inherited
DNA-binding domain of retroviral integrase1Inherited
HisI-like1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
mRNA decapping enzyme DcpS N-terminal domain0Direct
Metal cation-transporting ATPase, ATP-binding domain N0Direct
dUTPase-like0Direct
AN1-like Zinc finger0Direct
DHH phosphoesterases0Direct
Nudix0Direct
Dcp2 domain-like0Direct
Apyrase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Origin of replication-binding domain, RBD-like0Direct
HMA, heavy metal-associated domain0Direct
Soluble domain of poliovirus core protein 3a0Direct
all-alpha NTP pyrophosphatases0Direct
MOP-like0Direct
Nucleic acid-binding proteins0Direct
C-terminal domain of Ku800Direct
ABC transporter transmembrane region0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Restriction endonuclease-like0Direct
Sec63 N-terminal domain-like0Direct
EF-G C-terminal domain-like0Direct
Translation proteins0Direct
Positive stranded ssRNA viruses0Direct
Flavivirus capsid protein C0Direct
Metallo-dependent phosphatases0Direct
RuvA domain 2-like0Direct
Calcium ATPase, transduction domain A0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Inorganic pyrophosphatase0Direct
ITPase-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Acylphosphatase/BLUF domain-like0Direct
EndoU-like0Direct
Calcium ATPase, transmembrane domain M0Direct
BRK domain-like0Direct
DNA primase core0Direct
SPOC domain-like0Direct
Cdc48 domain 2-like0Direct
Rap30/74 interaction domains0Direct
HIT-like0Direct
Viral leader polypeptide zinc finger0Direct
N-terminal domain of DnaB helicase0Direct
"Winged helix" DNA-binding domain0Direct
DNA/RNA polymerases0Direct
HAD-like1.756e-16Direct
Tudor/PWWP/MBT0.0000000000006668Direct
Chromo domain-like0.00000000000127Direct
SAP domain0.00000000001719Direct
Hedgehog/intein (Hint) domain0.00000000001938Direct
Viral glycoprotein, central and dimerisation domains0.0000000003811Direct
vWA-like0.0000000008602Direct
Homing endonucleases0.000000002878Direct
Prokaryotic type I DNA topoisomerase0.000004814Direct
Coronavirus NSP8-like0.00002163Direct
Replicase NSP90.00002163Direct
Coronavirus NSP10-like0.00002163Direct
Coronavirus NSP7-like0.00002163Direct
MIT domain0.00002609Direct
E set domains0.0002513Direct
HRDC-like0.0004501Direct
Somatomedin B domain0.001043Inherited
NSP3A-like0.001129Inherited
WW domain0.003084Inherited
beta-sandwich domain of Sec23/240.006891Inherited
Bromodomain0.007183Inherited
FYVE/PHD zinc finger0.007211Inherited
RNA-binding domain, RBD0.009769Inherited
His-Me finger endonucleases0.01717Inherited
R3H domain0.0286Inherited
SARS Nsp1-like0.0477Inherited
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.1776Inherited
Trypsin-like serine proteases0.2448Inherited
CBS-domain pair0.4101Inherited
Ankyrin repeat0.4234Inherited
NTF2-like0.5131Inherited
CYTH-like phosphatases0.5978Inherited
HD-domain/PDEase-like0.7324Inherited
Clavaminate synthase-like0.8109Inherited
UBA-like0.904Inherited
Acid phosphatase/Vanadium-dependent haloperoxidase0.9753Inherited
PH domain-like1Inherited
N-terminal Zn binding domain of HIV integrase1Inherited
ADC-like1Inherited
Acid proteases1Inherited
Retrovirus zinc finger-like domains1Inherited
Actin-like ATPase domain1Inherited
Alkaline phosphatase-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
HisI-like1Inherited
DNA-binding domain of retroviral integrase1Inherited
Concanavalin A-like lectins/glucanases1Inherited
Ribonuclease Rh-like1Inherited
Macro domain-like1Inherited
SurE-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50447,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    50615,52540
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    101386,53720
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    52540,54928
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    50249,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0Direct
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    51283,51283
  • 51283 - dUTPase-like
  • 51283 - dUTPase-like
  • 0Direct
    53067,109604
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    81653,81665
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0Direct
    50916,46785
  • 50916 - Rap30/74 interaction domains
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0Direct
    52540,57756
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    55811,55811
  • 55811 - Nudix
  • 55811 - Nudix
  • 0Direct
    52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    55608,52540
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48024,52540
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    140586,55811
  • 140586 - Dcp2 domain-like
  • 55811 - Nudix
  • 0Direct
    101386,101386
  • 101386 - all-alpha NTP pyrophosphatases
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    81665,81660
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 0Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    51294,52540
  • 51294 - Hedgehog/intein (Hint) domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    102860,54197
  • 102860 - mRNA decapping enzyme DcpS N-terminal domain
  • 54197 - HIT-like
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    50331,50331
  • 50331 - MOP-like
  • 50331 - MOP-like
  • 0Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54980,54980
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    55464,52540
  • 55464 - Origin of replication-binding domain, RBD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,50331
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50331 - MOP-like
  • 0Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0Direct
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    81665,56784
  • 81665 - Calcium ATPase, transmembrane domain M
  • 56784 - HAD-like
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    52540,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    55608,56712
  • 55608 - Homing endonucleases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    141734,101386
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    52540,54631
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54631 - CBS-domain pair
  • 0Direct
    55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0.0000000000007057Direct
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.000000000001331Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0.0000000008725Direct
    51197,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000002093Direct
    56712,51294
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.00001708Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0.00002163Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0.00002163Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0.00002163Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0.0000863Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0.001043Inherited
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0.001043Inherited
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.001043Inherited
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0.001043Inherited
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0.001923Inherited
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.02637Inherited
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0.0477Inherited
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.06124Inherited
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0.1776Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 1Inherited
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 1Inherited
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 1Inherited
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 1Inherited
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    50249,52540,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0Direct
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,109604
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51294,55608,52540
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50447,54980,54980
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    51197,52540,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    52540,50447,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0Direct
    51197,52540,56672
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,56712,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,54980,54980
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54980 - EF-G C-terminal domain-like
  • 54980 - EF-G C-terminal domain-like
  • 0Direct
    55608,52540,47917
  • 55608 - Homing endonucleases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0Direct
    81653,81665,56784
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 56784 - HAD-like
  • 0Direct
    48024,52540,51294
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    81653,81665,81660
  • 81653 - Calcium ATPase, transduction domain A
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 0Direct
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    55008,55008,55008
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 55008 - HMA, heavy metal-associated domain
  • 0Direct
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    50615,52540,47917
  • 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    52540,52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    141734,101386,53720
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    81665,81660,56784
  • 81665 - Calcium ATPase, transmembrane domain M
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,50331,50331
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50331 - MOP-like
  • 50331 - MOP-like
  • 0Direct
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    52540,51294,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    52540,52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0.000000000000002433Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0.00002163Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0.00002163Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 0.0000863Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0.001043Inherited
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0.001043Inherited
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.001043Inherited
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0.001043Inherited
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0.001923Inherited
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 1Inherited
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 1Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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