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In phosphorous-containing anhydrides

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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Hydrolases [3] <13>(329|528) (368|389|207)
+ 1:   Acting on acid anhydrides [3.6] <5>(83|103) (94|93|62)
0:   In phosphorous-containing anhydrides [3.6.1] <67>(35|44) (40|33|19)
- 1:   2-hydroxy-dATP diphosphatase [3.6.1.56](0|0) (1|0|0)
- 1:   5'-acylphosphoadenosine hydrolase [3.6.1.20](0|0) (0|0|0)
- 1:   8-oxo-dGDP phosphatase [3.6.1.58](0|0) (1|0|0)
- 1:   8-oxo-dGTP diphosphatase [3.6.1.55](1|1) (1|0|0)
- 1:   ADP-ribose diphosphatase [3.6.1.13](1|2) (1|0|0)
- 1:   ADP-sugar diphosphatase [3.6.1.21](0|0) (0|0|0)
- 1:   ATP diphosphatase [3.6.1.8](0|0) (1|0|0)
- 1:   Acylphosphatase [3.6.1.7](1|1) (1|0|0)
- 1:   Adenosine-tetraphosphatase [3.6.1.14](0|0) (0|0|0)
- 1:   Adenosinetriphosphatase [3.6.1.3](1|1) (2|1|1)
- 1:   Apyrase [3.6.1.5](0|0) (1|1|0)
- 1:   Bis(5'-adenosyl)-triphosphatase [3.6.1.29](1|1) (1|0|0)
- 1:   Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) [3.6.1.17](2|2) (1|0|0)
- 1:   Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [3.6.1.41](1|1) (1|0|0)
- 1:   CDP-diacylglycerol diphosphatase [3.6.1.26](1|1) (1|0|0)
- 1:   CDP-glycerol diphosphatase [3.6.1.16](1|1) (1|0|0)
- 1:   D-tyrosyl-tRNA(Tyr) hydrolase [3.6.1.n1](0|0) (0|0|0)
- 1:   Deleted entry [3.6.1.30](0|0) (0|0|0)
- 1:   Diadenosine hexaphosphate hydrolase (AMP-forming) [3.6.1.60](0|0) (1|0|0)
- 1:   Diadenosine hexaphosphate hydrolase (ATP-forming) [3.6.1.61](0|0) (0|0|0)
- 1:   Dihydroneopterin triphosphate diphosphatase [3.6.1.n4](0|0) (0|0|0)
- 1:   Diphosphoinositol-polyphosphate diphosphatase [3.6.1.52](1|1) (1|0|0)
- 1:   Dolichyldiphosphatase [3.6.1.43](1|0) (1|0|0)
- 1:   Endopolyphosphatase [3.6.1.10](1|0) (1|0|0)
- 1:   Exopolyphosphatase [3.6.1.11](2|2) (2|1|0)
- 1:   FAD diphosphatase [3.6.1.18](0|0) (0|0|0)
- 1:   Guanosine-5'-triphosphate,3'-diphosphate diphospha [3.6.1.40](2|2) (2|2|1)
- 1:   Guanosine-diphosphatase [3.6.1.42](0|0) (0|0|0)
- 1:   Inorganic diphosphatase [3.6.1.1](3|4) (3|0|0)
- 1:   L-cysteinyl-tRNA(Cys) hydrolase [3.6.1.n3](0|0) (0|0|0)
- 1:   L-cysteinyl-tRNA(Pro) [3.6.1.n2](0|0) (0|0|0)
- 1:   M(7)GpppN-mRNA hydrolase [3.6.1.62](0|0) (2|1|0)
- 1:   M(7)GpppX diphosphatase [3.6.1.59](0|0) (2|1|0)
- 1:   Mn(2+)-dependent ADP-ribose/CDP-alcohol diphosphat [3.6.1.53](1|1) (1|0|0)
- 1:   NAD(+) diphosphatase [3.6.1.22](2|2) (2|1|0)
- 1:   Nucleoside phosphoacylhydrolase [3.6.1.24](0|0) (0|0|0)
- 1:   Nucleoside-diphosphatase [3.6.1.6](0|0) (1|0|0)
- 1:   Nucleoside-triphosphatase [3.6.1.15](11|14) (12|13|9)
- 1:   Nucleoside-triphosphate diphosphatase [3.6.1.19](1|1) (1|0|0)
- 1:   Nucleotide diphosphatase [3.6.1.9](3|1) (3|3|2)
- 1:   Oligosaccharide-diphosphodolichol diphosphatase [3.6.1.44](0|0) (0|0|0)
- 1:   Phosphoribosyl-ATP diphosphatase [3.6.1.31](2|3) (2|2|1)
- 1:   Thiamine-triphosphatase [3.6.1.28](1|1) (1|0|0)
- 1:   Thymidine-triphosphatase [3.6.1.39](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.1.3 [3.6.1.4](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.1.54 [3.6.1.n5](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.3.10 [3.6.1.36](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.3.14 [3.6.1.34](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.3.6 [3.6.1.35](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.3.8 [3.6.1.38](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.3.9 [3.6.1.37](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.4.1 [3.6.1.32](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.4.2 [3.6.1.33](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.1 [3.6.1.46](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.2 [3.6.1.47](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.3 [3.6.1.48](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.4 [3.6.1.49](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.5 [3.6.1.50](0|0) (0|0|0)
- 1:   Transferred entry: 3.6.5.6 [3.6.1.51](0|0) (0|0|0)
- 1:   Trimetaphosphatase [3.6.1.2](0|0) (0|0|0)
- 1:   Triphosphatase [3.6.1.25](0|0) (0|0|0)
- 1:   UDP-2,3-diacylglucosamine diphosphatase [3.6.1.54](1|0) (1|0|0)
- 1:   UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyr [3.6.1.57](0|0) (0|0|0)
- 1:   UDP-sugar diphosphatase [3.6.1.45](1|2) (1|1|0)
- 1:   Undecaprenyl-diphosphatase [3.6.1.27](0|0) (1|0|0)
- 1:   dCTP diphosphatase [3.6.1.12](1|0) (1|0|0)
- 1:   dUTP diphosphatase [3.6.1.23](4|6) (4|7|5)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
E set domains0Direct
DNA/RNA polymerases0Direct
HisI-like0Direct
Flavivirus capsid protein C0Direct
HIT-like0Direct
Positive stranded ssRNA viruses0Direct
all-alpha NTP pyrophosphatases0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Metallo-dependent phosphatases0Direct
HD-domain/PDEase-like0Direct
Inorganic pyrophosphatase0Direct
Soluble domain of poliovirus core protein 3a0Direct
DHH phosphoesterases0Direct
Nudix0Direct
dUTPase-like0Direct
ITPase-like0Direct
Acylphosphatase/BLUF domain-like0Direct
Trypsin-like serine proteases0Direct
Somatomedin B domain0.0000000000000101Direct
His-Me finger endonucleases0.0000000000004777Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0.000000000001906Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000002974Direct
SurE-like0.00000000009312Direct
Actin-like ATPase domain0.0000002262Direct
CYTH-like phosphatases0.0000008156Direct
Macro domain-like0.000001337Direct
N-terminal Zn binding domain of HIV integrase0.00001966Direct
DNA-binding domain of retroviral integrase0.00002131Direct
Ribonuclease Rh-like0.00004815Direct
Ankyrin repeat0.001342Inherited
Acid proteases0.006219Inherited
Alkaline phosphatase-like0.3205Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
HAD-like1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
HIT (HINT, histidine triad) family of protein kinase-interacting proteins0Direct
Manganese-dependent inorganic pyrophosphatase (family II)0Direct
MutT-like0Direct
Class II viral fusion proteins C-terminal domain0Direct
NADH pyrophosphatase0Direct
Inorganic pyrophosphatase0Direct
Viral proteases0Direct
RNA helicase0Direct
dUTPase-like0Direct
Protein serine/threonine phosphatase0Direct
Acylphosphatase-like0Direct
Ppx associated domain0Direct
RNA-dependent RNA-polymerase0Direct
Picornaviridae-like VP (VP1, VP2, VP3 and VP4)0Direct
Flavivirus capsid protein C0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Soluble domain of poliovirus core protein 3a0Direct
HisE-like (PRA-PH)0Direct
Ppx/GppA phosphatase0Direct
ITPase (Ham1)0Direct
Caliciviridae-like VP0Direct
ADPRibase-Mn-like0Direct
CDH-like0Direct
Viral cysteine protease of trypsin fold0Direct
mRNA cap methylase0Direct
HisI-like0Direct
beta-Phosphoglucomutase-like0.000000000000001381Direct
Somatomedin B domain0.000000000000003769Direct
CYTH domain0.000000000007552Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain0.00000000001183Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000001183Direct
SurE-like0.00000000001349Direct
NagD-like0.0000000009794Direct
Macro domain0.0000001895Direct
Retroviral protease (retropepsin)0.000003335Direct
N-terminal Zn binding domain of HIV integrase0.000008952Direct
DNA-binding domain of retroviral integrase0.000009712Direct
Ribonuclease Rh-like0.00002614Direct
Reverse transcriptase0.0002888Direct
Retroviral integrase, catalytic domain0.0007212Direct
Ankyrin repeat0.0007611Direct
L-histidinol dehydrogenase HisD0.03234Inherited
RecA protein-like (ATPase-domain)1Inherited
Extended AAA-ATPase domain1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
mRNA decapping enzyme DcpS N-terminal domain0Direct
dUTPase-like0Direct
DHH phosphoesterases0Direct
Nudix0Direct
Dcp2 domain-like0Direct
Apyrase0Direct
Soluble domain of poliovirus core protein 3a0Direct
all-alpha NTP pyrophosphatases0Direct
HD-domain/PDEase-like0Direct
Trypsin-like serine proteases0Direct
Positive stranded ssRNA viruses0Direct
HisI-like0Direct
E set domains0Direct
Flavivirus capsid protein C0Direct
Metallo-dependent phosphatases0Direct
Inorganic pyrophosphatase0Direct
ITPase-like0Direct
Acylphosphatase/BLUF domain-like0Direct
HIT-like0Direct
Viral leader polypeptide zinc finger0Direct
DNA/RNA polymerases0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Somatomedin B domain0.000000000000007766Direct
His-Me finger endonucleases0.0000000000003751Direct
Acid phosphatase/Vanadium-dependent haloperoxidase0.000000000001531Direct
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain0.00000000002377Direct
SurE-like0.00000000007905Direct
Actin-like ATPase domain0.0000002057Direct
CYTH-like phosphatases0.0000006786Direct
Macro domain-like0.00000124Direct
N-terminal Zn binding domain of HIV integrase0.0000168Direct
DNA-binding domain of retroviral integrase0.00001822Direct
Ribonuclease Rh-like0.00004098Direct
Ankyrin repeat0.001181Inherited
Acid proteases0.005541Inherited
Bromodomain0.03601Inherited
Alkaline phosphatase-like0.3004Inherited
HAD-like1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
P-loop containing nucleoside triphosphate hydrolases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
101386,53720
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    51283,51283
  • 51283 - dUTPase-like
  • 51283 - dUTPase-like
  • 0Direct
    53067,109604
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50494,56672
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    55811,55811
  • 55811 - Nudix
  • 55811 - Nudix
  • 0Direct
    52540,89043
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    140586,55811
  • 140586 - Dcp2 domain-like
  • 55811 - Nudix
  • 0Direct
    101386,101386
  • 101386 - all-alpha NTP pyrophosphatases
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    89043,50494
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    88633,50494
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    102860,54197
  • 102860 - mRNA decapping enzyme DcpS N-terminal domain
  • 54197 - HIT-like
  • 0Direct
    141734,101386
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 0Direct
    53649,54060
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 3.502e-16Direct
    51283,46919
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0.000000000000007766Direct
    53098,51283
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0.000000000000007766Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.000000000000007766Direct
    90188,90188
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 0.000000000000007766Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.000000000000436Direct
    56300,55816
  • 56300 - Metallo-dependent phosphatases
  • 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
  • 0.00000000002377Direct
    54001,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 0.0000000008292Direct
    56672,88633
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0.000000009786Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0.00001248Direct
    46919,53098
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0.00001547Direct
    53098,50122
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0.00001822Direct
    50630,56672
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 0.00003112Direct
    56672,53098
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0.0001403Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0.6708Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    89043,50494,56672
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,109604
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 109604 - HD-domain/PDEase-like
  • 0Direct
    50494,52540,89043
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 0Direct
    50494,56672,88633
  • 50494 - Trypsin-like serine proteases
  • 56672 - DNA/RNA polymerases
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    88633,88633,88633
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0Direct
    52540,89043,50494
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 89043 - Soluble domain of poliovirus core protein 3a
  • 50494 - Trypsin-like serine proteases
  • 0Direct
    52540,52540,47370
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47370 - Bromodomain
  • 0Direct
    50494,52540,56672
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    141734,101386,53720
  • 141734 - HisI-like
  • 101386 - all-alpha NTP pyrophosphatases
  • 53720 - ALDH-like
  • 0Direct
    88633,50494,52540
  • 88633 - Positive stranded ssRNA viruses
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    90188,53649,54060
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 54060 - His-Me finger endonucleases
  • 3.502e-16Direct
    53098,51283,46919
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 0.000000000000007766Direct
    56672,53098,51283
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 51283 - dUTPase-like
  • 0.000000000000007766Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0.000000000000007766Direct
    51283,46919,53098
  • 51283 - dUTPase-like
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 0.000000000000007766Direct
    54001,88633,88633
  • 54001 - Cysteine proteinases
  • 88633 - Positive stranded ssRNA viruses
  • 88633 - Positive stranded ssRNA viruses
  • 0.0000000008292Direct
    46919,53098,50122
  • 46919 - N-terminal Zn binding domain of HIV integrase
  • 53098 - Ribonuclease H-like
  • 50122 - DNA-binding domain of retroviral integrase
  • 0.00001309Direct
    50630,56672,53098
  • 50630 - Acid proteases
  • 56672 - DNA/RNA polymerases
  • 53098 - Ribonuclease H-like
  • 0.00002484Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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