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Acting on acid anhydrides; involved in cellular an

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Hydrolases [3] <13>(329|528) (368|389|207)
+ 1:   Acting on acid anhydrides [3.6] <5>(83|103) (94|93|62)
0:   Acting on acid anhydrides; involved in cellular an [3.6.4] <13>(46|55) (51|47|29)
- 1:   Chaperonin ATPase [3.6.4.9](0|0) (0|0|0)
- 1:   DNA helicase [3.6.4.12](25|33) (28|29|16)
- 1:   Dynein ATPase [3.6.4.2](0|0) (0|0|0)
- 1:   Microtubule-severing ATPase [3.6.4.3](1|1) (1|0|0)
- 1:   Minus-end-directed kinesin ATPase [3.6.4.5](0|0) (0|0|0)
- 1:   Myosin ATPase [3.6.4.1](0|0) (0|0|0)
- 1:   Non-chaperonin molecular chaperone ATPase [3.6.4.10](0|0) (0|0|0)
- 1:   Nucleoplasmin ATPase [3.6.4.11](0|0) (0|0|0)
- 1:   Peroxisome-assembly ATPase [3.6.4.7](0|0) (0|0|0)
- 1:   Plus-end-directed kinesin ATPase [3.6.4.4](0|0) (0|0|0)
- 1:   Proteasome ATPase [3.6.4.8](0|0) (0|0|0)
- 1:   RNA helicase [3.6.4.13](22|25) (25|20|9)
- 1:   Vesicle-fusing ATPase [3.6.4.6](2|3) (2|3|2)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
E set domains0Direct
RuvA domain 2-like0Direct
DNA/RNA polymerases0Direct
Restriction endonuclease-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
BRK domain-like0Direct
Macro domain-like0Direct
Cdc48 domain 2-like0Direct
Flavivirus capsid protein C0Direct
Sec63 N-terminal domain-like0Direct
Coronavirus NSP8-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Coronavirus NSP7-like0Direct
"Winged helix" DNA-binding domain0Direct
EndoU-like0Direct
C-terminal domain of Ku800Direct
Origin of replication-binding domain, RBD-like0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Rap30/74 interaction domains0Direct
HRDC-like0Direct
vWA-like0Direct
Tudor/PWWP/MBT0Direct
N-terminal domain of DnaB helicase0Direct
Nucleic acid-binding proteins0Direct
Replicase NSP90Direct
Chromo domain-like0Direct
SPOC domain-like0Direct
Coronavirus NSP10-like0Direct
NSP3A-like0Direct
SAP domain4.713e-16Direct
Prokaryotic type I DNA topoisomerase0.0000000000002586Direct
Trypsin-like serine proteases0.000000001469Direct
R3H domain0.000000002996Direct
MIT domain0.00000003868Direct
RNA-binding domain, RBD0.00000004046Direct
FYVE/PHD zinc finger0.0000003973Direct
WW domain0.000007733Direct
Retrovirus zinc finger-like domains0.00002155Direct
UBA-like0.0003685Direct
Ribonuclease Rh-like0.0004788Direct
Hedgehog/intein (Hint) domain0.003052Inherited
Clavaminate synthase-like0.008223Inherited
Homing endonucleases0.01072Inherited
Concanavalin A-like lectins/glucanases0.1378Inherited
ADC-like0.5931Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Coronavirus NSP8-like0Direct
Nsp15 C-terminal domain-like0Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Class II viral fusion proteins C-terminal domain0Direct
DNA helicase RuvA subunit, N-terminal domain0Direct
Replicase NSP90Direct
Replication initiation protein E10Direct
Viral proteases0Direct
RNA helicase0Direct
Chromo domain0Direct
DNA-binding domain from rap300Direct
Helicase-like "domain" of reverse gyrase0Direct
Sec63 N-terminal domain0Direct
C-terminal domain of Ku800Direct
Tandem AAA-ATPase domain0Direct
Ku70 subunit middle domain0Direct
DNA helicase RuvA subunit, middle domain0Direct
Ku80 subunit N-terminal domain0Direct
Nsp15 N-terminal domain-like0Direct
HRDC domain from helicases0Direct
RecQ helicase DNA-binding domain-like0Direct
Flavivirus capsid protein C0Direct
Viral glycoprotein, central and dimerisation domains0Direct
Tudor domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
Extended AAA-ATPase domain0Direct
Helicase DNA-binding domain0Direct
NSP3A-like0Direct
Sec63 C-terminal domain-like0Direct
Macro domain0Direct
Coronavirus NSP7-like0Direct
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain0Direct
GUCT domain0Direct
Coronavirus NSP10-like0Direct
Rap30/74 interaction domains0Direct
RecG "wedge" domain0Direct
Ku80 subunit middle domain0Direct
Cdc48 domain 2-like0Direct
BRK domain-like0Direct
mRNA cap methylase0Direct
N-terminal domain of DnaB helicase0Direct
Ku70 subunit N-terminal domain0Direct
Cdc48 N-terminal domain-like0Direct
SAP domain1.746e-16Direct
SPRY domain3.476e-16Direct
Prokaryotic type I DNA topoisomerase0.0000000000000833Direct
R3H domain0.000000001697Direct
AlkB-like0.00000001282Direct
WW domain0.000004631Direct
Retrovirus zinc finger-like domains0.00001143Direct
PHD domain0.0002735Direct
RNA-dependent RNA-polymerase0.0002909Direct
Ribonuclease Rh-like0.0003121Direct
Intein (protein splicing domain)0.002257Inherited
Viral cysteine protease of trypsin fold0.8415Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
AN1-like Zinc finger0Direct
Coronavirus NSP8-like0Direct
Origin of replication-binding domain, RBD-like0Direct
Nucleic acid-binding proteins0Direct
C-terminal domain of Ku800Direct
DNA helicase RuvA subunit, C-terminal domain0Direct
Restriction endonuclease-like0Direct
Sec63 N-terminal domain-like0Direct
Replicase NSP90Direct
E set domains0Direct
Flavivirus capsid protein C0Direct
RuvA domain 2-like0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Tudor/PWWP/MBT0Direct
NSP3A-like0Direct
Chromo domain-like0Direct
EndoU-like0Direct
BRK domain-like0Direct
DNA primase core0Direct
SPOC domain-like0Direct
Cdc48 domain 2-like0Direct
HRDC-like0Direct
vWA-like0Direct
Rap30/74 interaction domains0Direct
Macro domain-like0Direct
Coronavirus NSP10-like0Direct
N-terminal domain of DnaB helicase0Direct
Coronavirus NSP7-like0Direct
"Winged helix" DNA-binding domain0Direct
DNA/RNA polymerases0Direct
Viral glycoprotein, central and dimerisation domains0Direct
SAP domain3.502e-16Direct
Prokaryotic type I DNA topoisomerase0.0000000000001854Direct
Trypsin-like serine proteases0.000000001027Direct
R3H domain0.000000002327Direct
MIT domain0.00000003038Direct
RNA-binding domain, RBD0.00000003133Direct
FYVE/PHD zinc finger0.0000003113Direct
SARS Nsp1-like0.0000003464Direct
WW domain0.00000625Direct
Retrovirus zinc finger-like domains0.00001739Direct
beta-sandwich domain of Sec23/240.00007273Direct
Ribonuclease Rh-like0.0004004Direct
UBA-like0.0005134Direct
Hedgehog/intein (Hint) domain0.002578Inherited
Clavaminate synthase-like0.008591Inherited
Homing endonucleases0.009215Inherited
NTF2-like0.01618Inherited
Concanavalin A-like lectins/glucanases0.126Inherited
ADC-like0.5504Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
100939,68906
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    56672,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,54928
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    50249,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56983,81296
  • 56983 - Viral glycoprotein, central and dimerisation domains
  • 81296 - E set domains
  • 0Direct
    53335,52949
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 52949 - Macro domain-like
  • 0Direct
    52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    160481,160481
  • 160481 - BRK domain-like
  • 160481 - BRK domain-like
  • 0Direct
    158702,81296
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    50916,46785
  • 50916 - Rap30/74 interaction domains
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,57756
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    100939,101420
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    46785,47819
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    56731,52540
  • 56731 - DNA primase core
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46785,158702
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    49899,52540
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    158702,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48024,52540
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    53335,56672
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    140367,143076
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 0Direct
    47781,46929
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    54160,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53335,142877
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 142877 - EndoU-like
  • 0Direct
    52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    55464,52540
  • 55464 - Origin of replication-binding domain, RBD-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50249,47781
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 0Direct
    52540,49899
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0Direct
    101816,144246
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    55608,56712
  • 55608 - Homing endonucleases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0Direct
    143076,101816
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    52980,47781
  • 52980 - Restriction endonuclease-like
  • 47781 - RuvA domain 2-like
  • 0Direct
    51197,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0000000000006623Direct
    50494,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000003485Direct
    56712,51294
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.0000003012Direct
    159936,52949
  • 159936 - NSP3A-like
  • 52949 - Macro domain-like
  • 0.0000003464Direct
    159936,53335
  • 159936 - NSP3A-like
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.000004252Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0.000009655Direct
    52540,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0.03342Inherited
    51294,55608
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.0361Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50249,52540,52540
  • 50249 - Nucleic acid-binding proteins
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,46785,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 47819 - HRDC-like
  • 0Direct
    50494,52540,52540
  • 50494 - Trypsin-like serine proteases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    46785,158702,52540
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    51197,52540,52540
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,49899,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 49899 - Concanavalin A-like lectins/glucanases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53300,100939,101420
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 101420 - C-terminal domain of Ku80
  • 0Direct
    51197,52540,56672
  • 51197 - Clavaminate synthase-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    52540,56712,51294
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    140367,143076,101816
  • 140367 - Coronavirus NSP7-like
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 0Direct
    54160,54160,52540
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48024,52540,51294
  • 48024 - N-terminal domain of DnaB helicase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 0Direct
    52540,52540,56672
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56672 - DNA/RNA polymerases
  • 0Direct
    46785,158702,81296
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 81296 - E set domains
  • 0Direct
    56672,52540,52540
  • 56672 - DNA/RNA polymerases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,46785
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    158702,52540,52540
  • 158702 - Sec63 N-terminal domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,52540,142877
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 142877 - EndoU-like
  • 0Direct
    52540,46785,158702
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 46785 - "Winged helix" DNA-binding domain
  • 158702 - Sec63 N-terminal domain-like
  • 0Direct
    52540,52540,47819
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47819 - HRDC-like
  • 0Direct
    54160,52540,52540
  • 54160 - Chromo domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    143076,101816,144246
  • 143076 - Coronavirus NSP8-like
  • 101816 - Replicase NSP9
  • 144246 - Coronavirus NSP10-like
  • 0Direct
    50249,47781,46929
  • 50249 - Nucleic acid-binding proteins
  • 47781 - RuvA domain 2-like
  • 46929 - DNA helicase RuvA subunit, C-terminal domain
  • 0Direct
    53300,100939,68906
  • 53300 - vWA-like
  • 100939 - SPOC domain-like
  • 68906 - SAP domain
  • 0Direct
    52540,52540,56712
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 56712 - Prokaryotic type I DNA topoisomerase
  • 0Direct
    52540,51294,55608
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51294 - Hedgehog/intein (Hint) domain
  • 55608 - Homing endonucleases
  • 0.1247Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
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