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Lyases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   root [root] <6>
0:   Lyases [4] <7>(139|176) (158|94|34)
- 1:   Carbon-carbon lyases [4.1] <4>(54|67) (59|30|8)
- 1:   Carbon-nitrogen lyases [4.3] <4>(11|11) (11|6|2)
- 1:   Carbon-oxygen lyases [4.2] <4>(68|83) (76|43|20)
- 1:   Carbon-halide lyases [4.5] <1>(2|2) (2|1|0)
- 1:   Carbon-sulfur lyases [4.4] <1>(6|8) (7|1|0)
- 1:   Other lyases [4.99] <1>(7|8) (7|4|1)
- 1:   Phosphorus-oxygen lyases [4.6] <1>(9|8) (15|9|3)


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Urocanase0Direct
Hyaluronate lyase-like, C-terminal domain0Direct
PLP-binding barrel0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
HemD-like0Direct
Terpenoid synthases0Direct
RuBisCO, large subunit, small (N-terminal) domain0Direct
RuBisCo, C-terminal domain0Direct
DNA-glycosylase0Direct
PCD-like0Direct
lambda repressor-like DNA-binding domains0Direct
Chorismate lyase-like0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
S13-like H2TH domain0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
Aldolase0Direct
Cyanase C-terminal domain0Direct
Chorismate synthase, AroC0Direct
FAH0Direct
NosL/MerB-like0Direct
IlvD/EDD N-terminal domain-like0Direct
LeuD/IlvD-like0Direct
Chlorophyll a-b binding protein0Direct
beta-carbonic anhydrase, cab0Direct
IpsF-like0Direct
Alanine racemase C-terminal domain-like0Direct
Periplasmic binding protein-like I0Direct
Carbonic anhydrase0Direct
AraD/HMP-PK domain-like0Direct
PEP carboxykinase N-terminal domain0Direct
Ribosomal protein S5 domain 2-like0Direct
2-methylcitrate dehydratase PrpD0Direct
Tetrapyrrole methylase0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Type II 3-dehydroquinate dehydratase0Direct
RibA-like0Direct
S-adenosylmethionine decarboxylase0Direct
Acetoacetate decarboxylase-like0Direct
YrdC/RibB0Direct
LuxS/MPP-like metallohydrolase0Direct
Aconitase B, N-terminal domain0Direct
Chelatase0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
UROD/MetE-like0Direct
Lysozyme-like0Direct
ADC-like0Direct
Enolase C-terminal domain-like0Direct
Nucleotide cyclase0Direct
Ornithine decarboxylase C-terminal domain0Direct
post-HMGL domain-like0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
Enolase N-terminal domain-like0Direct
Pyruvoyl-dependent histidine and arginine decarboxylases0Direct
PEP carboxykinase-like0Direct
L-aspartase-like0Direct
Xylose isomerase-like0Direct
FumA C-terminal domain-like0Direct
RuBisCO, small subunit0Direct
Dehydroquinate synthase-like0Direct
Aconitase iron-sulfur domain0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
Siroheme synthase middle domains-like0Direct
Ribulose-phoshate binding barrel0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
Chondroitin AC/alginate lyase0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
ADC synthase0Direct
Pectin lyase-like0Direct
UraD-Like0.000000000001775Direct
AF0104/ALDC/Ptd012-like0.00000000002037Direct
CoaB-like0.0000000002666Direct
Nitrile hydratase alpha chain0.00000000166Direct
SIS domain0.000000002477Direct
ClpP/crotonase0.000000003872Direct
N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)0.000000004208Direct
Methylglyoxal synthase-like0.000000004493Direct
NHL repeat0.0000001589Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000001589Direct
Electron transport accessory proteins0.000000752Direct
Chorismate mutase II0.000001266Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0.000003428Direct
Serine metabolism enzymes domain0.00002634Direct
TATA-box binding protein-like0.0000344Direct
Periplasmic binding protein-like II0.00008606Direct
PHM/PNGase F0.00008747Direct
Tautomerase/MIF0.0002055Direct
ACT-like0.00038Direct
DHS-like NAD/FAD-binding domain0.003317Inherited
Calcium-dependent phosphotriesterase0.00446Inherited
Starch-binding domain-like0.0163Inherited
MAPEG domain-like0.02354Inherited
Mss4-like0.02642Inherited
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.03299Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.04828Inherited
DNase I-like0.2093Inherited
CBS-domain pair0.239Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.3899Inherited
Galactose mutarotase-like0.474Inherited
RmlC-like cupins0.5417Inherited
D-aminoacid aminotransferase-like PLP-dependent enzymes0.6132Inherited
Glutamine synthetase, N-terminal domain0.9467Inherited
Rudiment single hybrid motif1Inherited
EPT/RTPC-like1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
FabD/lysophospholipase-like1Inherited
Thioredoxin-like1Inherited
CoA-dependent acyltransferases1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Galactose-binding domain-like1Inherited
Class I glutamine amidotransferase-like1Inherited
SAICAR synthase-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
"Winged helix" DNA-binding domain1Inherited
GHMP Kinase, C-terminal domain1Inherited
ACP-like1Inherited
HAD-like1Inherited
Protein kinase-like (PK-like)1Inherited
GroES-like1Inherited
Thiolase-like1Inherited
Cytochrome P4501Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
Ribokinase-like1Inherited
alpha/beta-Hydrolases1Inherited
GST C-terminal domain-like1Inherited
Isocitrate/Isopropylmalate dehydrogenase-like1Inherited
PP2C-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
PLP-dependent transferases1Inherited
FAD/NAD(P)-binding domain1Inherited
PLC-like phosphodiesterases1Inherited
Glutamine synthetase/guanido kinase1Inherited
L domain-like1Inherited
FAD-linked reductases, C-terminal domain1Inherited
PreATP-grasp domain1Inherited
Metallo-dependent hydrolases1Inherited


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Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Rhamnogalacturonase B, RhgB, middle domain0Direct
Siroheme synthase middle domains-like0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
Chlorophyll a-b binding protein0Direct
FAH0Direct
Enolase N-terminal domain-like0Direct
Pyridoxal-dependent decarboxylase0Direct
Arginine decarboxylase0Direct
Dimeric chorismate mutase0Direct
Crotonase-like0Direct
C-terminal, Zn-finger domain of MutM-like DNA repair proteins0Direct
HCDH C-domain-like0Direct
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB0Direct
Cyanase N-terminal domain0Direct
Uroporphyrinogen decarboxylase, UROD0Direct
HAL/PAL-like0Direct
PEP carboxykinase C-terminal domain0Direct
Decarboxylase0Direct
IpsF-like0Direct
S-adenosylmethionine decarboxylase0Direct
MaoC-like0Direct
ADC synthase0Direct
lvD/EDD N-terminal domain-like0Direct
Histidinol phosphatase-like0Direct
Urocanase0Direct
HpcH/HpaI aldolase0Direct
IlvD/EDD C-terminal domain-like0Direct
Middle domain of MutM-like DNA repair proteins0Direct
Chorismate lyase0Direct
Alpha-acetolactate decarboxylase-like0Direct
Type II 3-dehydroquinate dehydratase0Direct
Glyoxalase I (lactoylglutathione lyase)0Direct
Chorismate synthase, AroC0Direct
Terpenoid cyclase C-terminal domain0Direct
Mevalonate 5-diphosphate decarboxylase0Direct
Beta-eliminating lyases0Direct
Allosteric threonine deaminase C-terminal domain0Direct
Ornithine decarboxylase major domain0Direct
2-methylcitrate dehydratase PrpD0Direct
Bacterial muramidase, catalytic domain0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
UxuA-like0Direct
beta-Hydroxydecanol thiol ester dehydrase0Direct
Bacterial PLC0Direct
Endonuclease III0Direct
RuBisCO, small subunit0Direct
MerB N-terminal domain-like0Direct
Rhamnogalacturonase B, RhgB, N-terminal domain0Direct
DHN aldolase/epimerase0Direct
Pyruvoyl dependent aspartate decarboxylase, ADC0Direct
Ribulose 1,5-bisphosphate carboxylase-oxygenase0Direct
Acetoacetate decarboxylase-like0Direct
FumA C-terminal domain-like0Direct
Dehydroquinate synthase, DHQS0Direct
Methylglyoxal synthase, MgsA0Direct
Autoinducer-2 production protein LuxS0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
HMGL-like0Direct
Enolase0Direct
Siroheme synthase N-terminal domain-like0Direct
Histidine decarboxylase0Direct
Rhamnogalacturonase B, RhgB, C-terminal domain0Direct
Terpenoid cyclase N-terminal domain0Direct
PEP carboxykinase N-terminal domain0Direct
DmpG/LeuA communication domain-like0Direct
6-pyruvoyl tetrahydropterin synthase0Direct
Aconitase iron-sulfur domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
LeuD-like0Direct
Bacterial S-adenosylmethionine decarboxylase0Direct
CbiX-like0Direct
Phosphoenolpyruvate mutase/Isocitrate lyase-like0Direct
PCD-like0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Pectin lyase0Direct
Cyanase C-terminal domain0Direct
Aristolochene/pentalenene synthase0Direct
L-arabinose binding protein-like0Direct
Alginate lyase A1-III0Direct
mono-SIS domain0Direct
Tetrapyrrole methylase0Direct
beta-carbonic anhydrase, cab0Direct
AgoG-like0Direct
Tryptophan biosynthesis enzymes0Direct
Alanine racemase-like, N-terminal domain0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
RibA-like0Direct
MerB-like0Direct
Aconitase B, N-terminal domain0Direct
H-NOX domain0Direct
Formaldehyde-activating enzyme, FAE0Direct
Trichodiene synthase0Direct
Phosphoenolpyruvate carboxylase0Direct
AraD-like aldolase/epimerase0Direct
Pectate lyase-like0Direct
DJ-1/PfpI0Direct
YjeF C-terminal domain-like0Direct
Ferrochelatase0Direct
Hyaluronate lyase-like catalytic, N-terminal domain0Direct
HemD-like0Direct
Carbonic anhydrase0Direct
RuBisCo, large subunit, C-terminal domain0Direct
Eukaryotic ODC-like0Direct
Ornithine decarboxylase C-terminal domain0Direct
Hyaluronate lyase-like, central domain0Direct
Glutathione-dependent formaldehyde-activating enzyme, Gfa0Direct
Class I aldolase0Direct
Serine dehydratase beta chain-like0Direct
L-aspartase/fumarase0Direct
Imidazole glycerol phosphate dehydratase0Direct
Class II FBP aldolase0Direct
D-glucarate dehydratase-like0Direct
Hypothetical protein VC19740Direct
5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)0Direct
Adenylyl and guanylyl cyclase catalytic domain0Direct
Hyaluronate lyase-like, C-terminal domain0Direct
PP1699/LP2961-like0Direct
UraD-like0.000000000002503Direct
Pyruvate oxidase and decarboxylase, middle domain0.00000000000514Direct
CoaB-like0.0000000003957Direct
Nitrile hydratase beta chain0.000000002064Direct
Nitrile hydratase alpha chain0.000000002064Direct
N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)0.000000007824Direct
DNase I-like0.0000000344Direct
Phenylalanine metabolism regulatory domain0.00000005526Direct
NHL repeat0.0000001813Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000001813Direct
Ornithine cyclodeaminase-like0.0000009382Direct
Acyl-carrier protein (ACP)0.000001696Direct
DNA repair glycosylase, N-terminal domain0.00003793Direct
Cystathionine synthase-like0.00005429Direct
Peptidylglycine alpha-hydroxylating monooxygenase, PHM0.00005788Direct
DNA repair glycosylase, 2 C-terminal domains0.0001623Direct
MIF-related0.0001658Direct
Shikimate kinase (AroK)0.0001741Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.001397Inherited
Pyruvate oxidase and decarboxylase PP module0.00207Inherited
6-phosphogluconate dehydrogenase-like, N-terminal domain0.01169Inherited
Shikimate dehydrogenase-like0.02273Inherited
MAPEG domain0.02572Inherited
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.0368Inherited
FabD-like0.04156Inherited
Phosphate binding protein-like0.06758Inherited
Terpene synthases0.1203Inherited
Pyruvate oxidase and decarboxylase Pyr module0.2098Inherited
Cytidylytransferase0.2413Inherited
CBS-domain pair0.2489Inherited
Branched-chain alpha-keto acid dehydrogenase Pyr module0.749Inherited
D-aminoacid aminotransferase-like PLP-dependent enzymes0.7813Inherited
CAT-like0.8544Inherited
Branched-chain alpha-keto acid dehydrogenase PP module0.9282Inherited
Glutamine synthetase, N-terminal domain0.9333Inherited
Glutamine synthetase catalytic domain0.9713Inherited
Glutathione S-transferase (GST), N-terminal domain1Inherited
Enolpyruvate transferase, EPT1Inherited
Tyrosine-dependent oxidoreductases1Inherited
Glutathione S-transferase (GST), C-terminal domain1Inherited
Thiolase-related1Inherited
Protein kinases, catalytic subunit1Inherited
BC N-terminal domain-like1Inherited
GHMP Kinase, N-terminal domain1Inherited
Enolase-phosphatase E11Inherited
AAT-like1Inherited
Alcohol dehydrogenase-like, N-terminal domain1Inherited
Cytochrome P4501Inherited
BC ATP-binding domain-like1Inherited
Class I glutamine amidotransferases (GAT)1Inherited
SAICAR synthase1Inherited
Alcohol dehydrogenase-like, C-terminal domain1Inherited
PP2C-like1Inherited
Dimeric isocitrate & isopropylmalate dehydrogenases1Inherited
FAD-linked reductases, N-terminal domain1Inherited
GMC oxidoreductases1Inherited
Aminoacid dehydrogenase-like, C-terminal domain1Inherited
BC C-terminal domain-like1Inherited
GABA-aminotransferase-like1Inherited


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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
IpsF-like0Direct
Type II 3-dehydroquinate dehydratase0Direct
NosL/MerB-like0Direct
Terpenoid cyclases/Protein prenyltransferases0Direct
YrdC/RibB0Direct
Enolase C-terminal domain-like0Direct
N-terminal domain of MutM-like DNA repair proteins0Direct
ADC-like0Direct
AraD/HMP-PK domain-like0Direct
Cryptochrome/photolyase FAD-binding domain0Direct
post-HMGL domain-like0Direct
Aldolase0Direct
2-methylcitrate dehydratase PrpD0Direct
HemD-like0Direct
S13-like H2TH domain0Direct
Chondroitin AC/alginate lyase0Direct
Chlorophyll a-b binding protein0Direct
Cryptochrome/photolyase, N-terminal domain0Direct
Periplasmic binding protein-like I0Direct
DNA-glycosylase0Direct
PEP carboxykinase-like0Direct
Dehydroquinate synthase-like0Direct
Carbonic anhydrase0Direct
Terpenoid synthases0Direct
Tryptophan synthase beta subunit-like PLP-dependent enzymes0Direct
Chorismate synthase, AroC0Direct
IlvD/EDD N-terminal domain-like0Direct
lambda repressor-like DNA-binding domains0Direct
L-aspartase-like0Direct
Bacterial muramidases0Direct
UROD/MetE-like0Direct
beta-carbonic anhydrase, cab0Direct
Enolase N-terminal domain-like0Direct
Aconitase iron-sulfur domain0Direct
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD0Direct
FumA C-terminal domain-like0Direct
Aconitase B, N-terminal domain0Direct
Lysozyme-like0Direct
Ligand-binding domain in the NO signalling and Golgi transport0Direct
Pectin lyase-like0Direct
Siroheme synthase middle domains-like0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
Chorismate lyase-like0Direct
Urocanase0Direct
FAH0Direct
RuBisCo, C-terminal domain0Direct
LuxS/MPP-like metallohydrolase0Direct
Glucocorticoid receptor-like (DNA-binding domain)0Direct
PEP carboxykinase N-terminal domain0Direct
PCD-like0Direct
Chelatase0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
RibA-like0Direct
Acetoacetate decarboxylase-like0Direct
LeuD/IlvD-like0Direct
Nucleotide cyclase0Direct
S-adenosylmethionine decarboxylase0Direct
Ornithine decarboxylase C-terminal domain0Direct
Xylose isomerase-like0Direct
Cyanase C-terminal domain0Direct
Hyaluronate lyase-like, C-terminal domain0Direct
Alanine racemase C-terminal domain-like0Direct
PLP-binding barrel0Direct
RuBisCO, small subunit0Direct
Tetrapyrrole methylase0Direct
Ribosomal protein S5 domain 2-like0Direct
Adenylylcyclase toxin (the edema factor)0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
ADC synthase0Direct
Pyruvoyl-dependent histidine and arginine decarboxylases0Direct
Ribulose-phoshate binding barrel0Direct
RuBisCO, large subunit, small (N-terminal) domain0Direct
(2r)-phospho-3-sulfolactate synthase ComA0Direct
UraD-Like0.00000000000131Direct
AF0104/ALDC/Ptd012-like0.0000000000152Direct
CoaB-like0.0000000002016Direct
Nitrile hydratase alpha chain0.000000001281Direct
SIS domain0.000000001982Direct
ClpP/crotonase0.0000000024Direct
Methylglyoxal synthase-like0.00000000302Direct
N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)0.000000003188Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000001258Direct
NHL repeat0.0000001258Direct
Electron transport accessory proteins0.0000005968Direct
Chorismate mutase II0.000001002Direct
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase0.000002676Direct
Serine metabolism enzymes domain0.0000213Direct
TATA-box binding protein-like0.00002815Direct
Periplasmic binding protein-like II0.00006655Direct
PHM/PNGase F0.00007181Direct
Tautomerase/MIF0.0001696Direct
ACT-like0.0002997Direct
DHS-like NAD/FAD-binding domain0.002721Inherited
Barwin-like endoglucanases0.003167Inherited
Calcium-dependent phosphotriesterase0.003776Inherited
DAK1/DegV-like0.004961Inherited
DhaL-like0.004961Inherited
Starch-binding domain-like0.01399Inherited
SCP-like0.01462Inherited
MAPEG domain-like0.02046Inherited
Mss4-like0.02254Inherited
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK0.02878Inherited
Ran binding protein zinc finger-like0.03863Inherited
6-phosphogluconate dehydrogenase C-terminal domain-like0.05341Inherited
DNase I-like0.1794Inherited
CBS-domain pair0.2299Inherited
Galactose mutarotase-like0.3497Inherited
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.3583Inherited
SMAD/FHA domain0.361Inherited
RmlC-like cupins0.4961Inherited
D-aminoacid aminotransferase-like PLP-dependent enzymes0.5705Inherited
RNI-like0.5985Inherited
UBA-like0.7312Inherited
NTF2-like0.8605Inherited
Glutamine synthetase, N-terminal domain0.8901Inherited
Dihydropteroate synthetase-like1Inherited
GHMP Kinase, C-terminal domain1Inherited
TPR-like1Inherited
PP2C-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Isocitrate/Isopropylmalate dehydrogenase-like1Inherited
FAD/NAD(P)-binding domain1Inherited
GroES-like1Inherited
NagB/RpiA/CoA transferase-like1Inherited
Nucleotide-diphospho-sugar transferases1Inherited
Thioredoxin-like1Inherited
ACP-like1Inherited
Cytochrome P4501Inherited
Metallo-dependent hydrolases1Inherited
L domain-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
Rudiment single hybrid motif1Inherited
Thiamin diphosphate-binding fold (THDP-binding)1Inherited
Single hybrid motif1Inherited
HAD-like1Inherited
Protein kinase-like (PK-like)1Inherited
PLC-like phosphodiesterases1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
Glutamine synthetase/guanido kinase1Inherited
EPT/RTPC-like1Inherited
PLP-dependent transferases1Inherited
PFL-like glycyl radical enzymes1Inherited
alpha/beta-Hydrolases1Inherited
PreATP-grasp domain1Inherited
Ribokinase-like1Inherited
Acylphosphatase/BLUF domain-like1Inherited
FabD/lysophospholipase-like1Inherited
SAICAR synthase-like1Inherited
Galactose-binding domain-like1Inherited
GST C-terminal domain-like1Inherited
Thiolase-like1Inherited
CoA-dependent acyltransferases1Inherited
Class I glutamine amidotransferase-like1Inherited
Aminoacid dehydrogenase-like, N-terminal domain1Inherited
Tetrahydrobiopterin biosynthesis enzymes-like1Inherited
"Winged helix" DNA-binding domain1Inherited
FAD-linked reductases, C-terminal domain1Inherited
CheY-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54966,51649
  • 54966 - RuBisCO, large subunit, small (N-terminal) domain
  • 51649 - RuBisCo, C-terminal domain
  • 0Direct
    53383,55904
  • 53383 - PLP-dependent transferases
  • 55904 - Ornithine decarboxylase C-terminal domain
  • 0Direct
    55205,52540
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48230,74650
  • 48230 - Chondroitin AC/alginate lyase
  • 74650 - Galactose mutarotase-like
  • 0Direct
    53732,52016
  • 53732 - Aconitase iron-sulfur domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    51735,54637
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    49452,49785
  • 49452 - Starch-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    52317,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    53850,53955
  • 53850 - Periplasmic binding protein-like II
  • 53955 - Lysozyme-like
  • 0Direct
    54211,51366
  • 54211 - Ribosomal protein S5 domain 2-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    56784,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    54637,55718
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55718 - SCP-like
  • 0Direct
    51569,53223
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    53686,54631
  • 53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
  • 54631 - CBS-domain pair
  • 0Direct
    48600,53850
  • 48600 - Chorismate mutase II
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    52016,53732
  • 52016 - LeuD/IlvD-like
  • 53732 - Aconitase iron-sulfur domain
  • 0Direct
    52540,51569
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    51366,53686
  • 51366 - Ribulose-phoshate binding barrel
  • 53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
  • 0Direct
    51569,89000
  • 51569 - Aldolase
  • 89000 - post-HMGL domain-like
  • 0Direct
    56104,52255
  • 56104 - SAICAR synthase-like
  • 52255 - N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
  • 0Direct
    68923,53795
  • 68923 - PEP carboxykinase N-terminal domain
  • 53795 - PEP carboxykinase-like
  • 0Direct
    55821,142695
  • 55821 - YrdC/RibB
  • 142695 - RibA-like
  • 0Direct
    53448,69765
  • 53448 - Nucleotide-diphospho-sugar transferases
  • 69765 - IpsF-like
  • 0Direct
    47413,55234
  • 47413 - lambda repressor-like DNA-binding domains
  • 55234 - Cyanase C-terminal domain
  • 0Direct
    52172,53383
  • 52172 - CheY-like
  • 53383 - PLP-dependent transferases
  • 0Direct
    48557,55729
  • 48557 - L-aspartase-like
  • 55729 - Acyl-CoA N-acyltransferases (Nat)
  • 0Direct
    74650,49863
  • 74650 - Galactose mutarotase-like
  • 49863 - Hyaluronate lyase-like, C-terminal domain
  • 0Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0Direct
    56529,56529
  • 56529 - FAH
  • 56529 - FAH
  • 0Direct
    46785,160387
  • 46785 - "Winged helix" DNA-binding domain
  • 160387 - NosL/MerB-like
  • 0Direct
    46946,57716
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    53639,56784
  • 53639 - AraD/HMP-PK domain-like
  • 56784 - HAD-like
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    81624,46946
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 0Direct
    55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    56322,52317
  • 56322 - ADC synthase
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    143975,52016
  • 143975 - IlvD/EDD N-terminal domain-like
  • 52016 - LeuD/IlvD-like
  • 0Direct
    54975,55073
  • 54975 - Acylphosphatase/BLUF domain-like
  • 55073 - Nucleotide cyclase
  • 0Direct
    55073,52540
  • 55073 - Nucleotide cyclase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52096,51735
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    53697,46934
  • 53697 - SIS domain
  • 46934 - UBA-like
  • 0Direct
    74778,52016
  • 74778 - Aconitase B, N-terminal domain
  • 52016 - LeuD/IlvD-like
  • 0Direct
    52317,47648
  • 52317 - Class I glutamine amidotransferase-like
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 0Direct
    53686,55021
  • 53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
  • 55021 - ACT-like
  • 0Direct
    53850,55021
  • 53850 - Periplasmic binding protein-like II
  • 55021 - ACT-like
  • 0Direct
    52425,48173
  • 52425 - Cryptochrome/photolyase, N-terminal domain
  • 48173 - Cryptochrome/photolyase FAD-binding domain
  • 0Direct
    52507,102645
  • 52507 - Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
  • 102645 - CoaB-like
  • 0Direct
    75615,53790
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
  • 0Direct
    51246,52255
  • 51246 - Rudiment single hybrid motif
  • 52255 - N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
  • 0Direct
    53271,51366
  • 53271 - PRTase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    55116,55116
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 0Direct
    54211,54211
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    55116,101262
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 101262 - Methenyltetrahydrofolate cyclohydrolase-like
  • 0Direct
    51366,51366
  • 51366 - Ribulose-phoshate binding barrel
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    81606,55073
  • 81606 - PP2C-like
  • 55073 - Nucleotide cyclase
  • 0Direct
    53822,56112
  • 53822 - Periplasmic binding protein-like I
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48179,48179
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    48435,53955
  • 48435 - Bacterial muramidases
  • 53955 - Lysozyme-like
  • 0Direct
    74650,49452
  • 74650 - Galactose mutarotase-like
  • 49452 - Starch-binding domain-like
  • 0Direct
    53800,103511
  • 53800 - Chelatase
  • 103511 - Chlorophyll a-b binding protein
  • 0Direct
    56796,55205
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 0Direct
    54826,51604
  • 54826 - Enolase N-terminal domain-like
  • 51604 - Enolase C-terminal domain-like
  • 0Direct
    51735,75615
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
  • 0Direct
    48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 0Direct
    55073,55073
  • 55073 - Nucleotide cyclase
  • 55073 - Nucleotide cyclase
  • 0Direct
    48239,48239
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 0.00000000000005006Direct
    51419,50621
  • 51419 - PLP-binding barrel
  • 50621 - Alanine racemase C-terminal domain-like
  • 0.000004441Direct
    52467,52518
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0.000004708Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000007816Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0.000008419Direct
    52518,52467
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 0.00001147Direct
    55945,48150
  • 55945 - TATA-box binding protein-like
  • 48150 - DNA-glycosylase
  • 0.00002815Direct
    49742,49742
  • 49742 - PHM/PNGase F
  • 49742 - PHM/PNGase F
  • 0.00007181Direct
    48179,52096
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52096 - ClpP/crotonase
  • 0.0001208Direct
    54593,54593
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 54593 - Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
  • 0.0001732Direct
    52058,81606
  • 52058 - L domain-like
  • 81606 - PP2C-like
  • 0.0005447Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0009867Direct
    55083,51717
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0.003167Inherited
    82549,101473
  • 82549 - DAK1/DegV-like
  • 101473 - DhaL-like
  • 0.004961Inherited
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.02046Inherited
    51735,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0.05249Inherited
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0.09487Inherited
    55620,55620
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 0.1046Inherited
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0.3583Inherited
    54368,55931
  • 54368 - Glutamine synthetase, N-terminal domain
  • 55931 - Glutamine synthetase/guanido kinase
  • 0.8901Inherited
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited
    53223,51735
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited
    52518,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 1Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    51905,54373
  • 51905 - FAD/NAD(P)-binding domain
  • 54373 - FAD-linked reductases, C-terminal domain
  • 1Inherited
    54211,55060
  • 54211 - Ribosomal protein S5 domain 2-like
  • 55060 - GHMP Kinase, C-terminal domain
  • 1Inherited
    55021,55021
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 1Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53822,56112,55073
  • 53822 - Periplasmic binding protein-like I
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0Direct
    56796,55205,52540
  • 56796 - Dehydroquinate synthase-like
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52172,53383,55904
  • 52172 - CheY-like
  • 53383 - PLP-dependent transferases
  • 55904 - Ornithine decarboxylase C-terminal domain
  • 0Direct
    56059,51246,52255
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 52255 - N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
  • 0Direct
    52317,47648,52418
  • 52317 - Class I glutamine amidotransferase-like
  • 47648 - Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
  • 52418 - Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
  • 0Direct
    51735,54637,54637
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    51735,48179,48179
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    51735,51735,54637
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    48239,48239,48576
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48239 - Terpenoid cyclases/Protein prenyltransferases
  • 48576 - Terpenoid synthases
  • 0Direct
    54637,54637,55718
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55718 - SCP-like
  • 0Direct
    55116,55116,101262
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 101262 - Methenyltetrahydrofolate cyclohydrolase-like
  • 0Direct
    55620,55083,51717
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 51717 - Dihydropteroate synthetase-like
  • 0Direct
    53686,55021,55021
  • 53686 - Tryptophan synthase beta subunit-like PLP-dependent enzymes
  • 55021 - ACT-like
  • 55021 - ACT-like
  • 0Direct
    74650,49452,49785
  • 74650 - Galactose mutarotase-like
  • 49452 - Starch-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0Direct
    51569,53223,51735
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    81624,46946,57716
  • 81624 - N-terminal domain of MutM-like DNA repair proteins
  • 46946 - S13-like H2TH domain
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    74778,52016,53732
  • 74778 - Aconitase B, N-terminal domain
  • 52016 - LeuD/IlvD-like
  • 53732 - Aconitase iron-sulfur domain
  • 0Direct
    52317,51366,51366
  • 52317 - Class I glutamine amidotransferase-like
  • 51366 - Ribulose-phoshate binding barrel
  • 51366 - Ribulose-phoshate binding barrel
  • 0Direct
    55205,52540,51569
  • 55205 - EPT/RTPC-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 0Direct
    48600,53850,55021
  • 48600 - Chorismate mutase II
  • 53850 - Periplasmic binding protein-like II
  • 55021 - ACT-like
  • 0Direct
    52096,51735,48179
  • 52096 - ClpP/crotonase
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 0Direct
    56784,54211,54211
  • 56784 - HAD-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    55620,55620,55083
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55620 - Tetrahydrobiopterin biosynthesis enzymes-like
  • 55083 - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
  • 0Direct
    51735,75615,53790
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 75615 - Siroheme synthase middle domains-like
  • 53790 - Tetrapyrrole methylase
  • 0Direct
    55073,55073,52540
  • 55073 - Nucleotide cyclase
  • 55073 - Nucleotide cyclase
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,51569,53223
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 51569 - Aldolase
  • 53223 - Aminoacid dehydrogenase-like, N-terminal domain
  • 0Direct
    52058,81606,55073
  • 52058 - L domain-like
  • 81606 - PP2C-like
  • 55073 - Nucleotide cyclase
  • 0Direct
    48230,74650,49863
  • 48230 - Chondroitin AC/alginate lyase
  • 74650 - Galactose mutarotase-like
  • 49863 - Hyaluronate lyase-like, C-terminal domain
  • 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000001245Direct
    52518,52467,52518
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52467 - DHS-like NAD/FAD-binding domain
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 0.00001009Direct
    48179,48179,52096
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 48179 - 6-phosphogluconate dehydrogenase C-terminal domain-like
  • 52096 - ClpP/crotonase
  • 0.0001208Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0006287Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.0127Inherited
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 1Inherited


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