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Ligases forming aminoacyl-tRNA and related compoun

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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Ligases [6] <6>(80|99) (88|104|66)
+ 1:   Forming carbon-oxygen bonds [6.1] <2>(28|31) (29|36|21)
0:   Ligases forming aminoacyl-tRNA and related compoun [6.1.1] <29>(28|31) (29|36|21)
- 1:   Alanine--tRNA ligase [6.1.1.7](4|4) (4|4|3)
- 1:   Arginine--tRNA ligase [6.1.1.19](3|3) (3|2|1)
- 1:   Asparagine--tRNA ligase [6.1.1.22](2|2) (2|1|0)
- 1:   Aspartate--tRNA ligase [6.1.1.12](3|3) (3|2|1)
- 1:   Aspartate--tRNA(Asn) ligase [6.1.1.23](0|0) (0|0|0)
- 1:   Cysteine--tRNA ligase [6.1.1.16](2|2) (2|1|0)
- 1:   D-alanine--poly(phosphoribitol) ligase [6.1.1.13](2|2) (2|0|0)
- 1:   Deleted entry [6.1.1.8](0|0) (0|0|0)
- 1:   Glutamate--tRNA ligase [6.1.1.17](3|3) (4|4|3)
- 1:   Glutamate--tRNA(Gln) ligase [6.1.1.24](0|0) (0|0|0)
- 1:   Glutamine--tRNA ligase [6.1.1.18](2|2) (2|1|0)
- 1:   Glycine--tRNA ligase [6.1.1.14](1|2) (2|2|0)
- 1:   Histidine--tRNA ligase [6.1.1.21](3|3) (3|2|1)
- 1:   Isoleucine--tRNA ligase [6.1.1.5](3|3) (3|2|0)
- 1:   Leucine--tRNA ligase [6.1.1.4](3|3) (3|2|1)
- 1:   Lysine--tRNA ligase [6.1.1.6](2|3) (3|2|0)
- 1:   Lysine--tRNA(Pyl) ligase [6.1.1.25](0|0) (0|0|0)
- 1:   Methionine--tRNA ligase [6.1.1.10](4|4) (4|4|3)
- 1:   O-phosphoserine--tRNA ligase [6.1.1.27](0|0) (0|0|0)
- 1:   Phenylalanine--tRNA ligase [6.1.1.20](7|6) (7|7|4)
- 1:   Proline--tRNA ligase [6.1.1.15](4|4) (4|5|4)
- 1:   Pyrrolysine--tRNA(Pyl) ligase [6.1.1.26](0|0) (0|0|0)
- 1:   Serine--tRNA ligase [6.1.1.11](2|2) (2|1|0)
- 1:   Threonine--tRNA ligase [6.1.1.3](4|4) (4|3|2)
- 1:   Transferred entry: 6.1.1.27 [6.1.1.n2](0|0) (0|0|0)
- 1:   Transferred entry: 6.3.1.13 [6.1.1.n1](0|0) (0|0|0)
- 1:   Tryptophan--tRNA ligase [6.1.1.2](3|3) (3|2|0)
- 1:   Tyrosine--tRNA ligase [6.1.1.1](2|2) (2|2|0)
- 1:   Valine--tRNA ligase [6.1.1.9](4|4) (5|2|1)


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
YegP-like0Direct
Ribosomal protein L25-like0Direct
ThrRS/AlaRS common domain0Direct
Translation proteins0Direct
Anticodon-binding domain of PheRS0Direct
Alpha-L RNA-binding motif0Direct
ACP-like0Direct
An anticodon-binding domain of class I aminoacyl-tRNA synthetases0Direct
S15/NS1 RNA-binding domain0Direct
HD-domain/PDEase-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Class II aaRS and biotin synthetases0Direct
Class II aaRS ABD-related0Direct
YbaK/ProRS associated domain0Direct
C-terminal domain of ProRS0Direct
TGS-like0Direct
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)0Direct
Nucleic acid-binding proteins0Direct
PheT/TilS domain0Direct
Nucleotidylyl transferase0Direct
tRNA-binding arm0Direct
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain0Direct
Methionyl-tRNA synthetase (MetRS), Zn-domain0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Putative DNA-binding domain0Direct
GAD domain-like0Direct
Acetyl-CoA synthetase-like0.00973Inherited
"Winged helix" DNA-binding domain1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain0Direct
B3/B4 domain of PheRS, PheT0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Anticodon-binding domain0Direct
Phenylalanyl-tRNA synthetase (PheRS)0Direct
Anticodon-binding domain of PheRS0Direct
YbaK/ProRS associated domain0Direct
C-terminal domain of glutamyl-tRNA synthetase (GluRS)0Direct
apo-D-alanyl carrier protein0Direct
Valyl-tRNA synthetase (ValRS) C-terminal domain0Direct
YegP-like0Direct
Tyrosyl-tRNA synthetase (TyrRS), C-terminal domain0Direct
Threonyl-tRNA synthetase (ThrRS), second 'additional' domain0Direct
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)0Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0Direct
C-terminal domain of ProRS0Direct
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain0Direct
Methionyl-tRNA synthetase (MetRS), Zn-domain0Direct
Myf domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
a tRNA synthase domain0Direct
Domains B1 and B5 of PheRS-beta, PheT0Direct
AlaX-M N-terminal domain-like0Direct
GAD domain0Direct
C-terminal domain of class I lysyl-tRNA synthetase0Direct
AlaX-like0Direct
Seryl-tRNA synthetase (SerRS)0Direct
TGS domain0Direct
Acetyl-CoA synthetase-like0.01579Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nucleotidylyl transferase0Direct
Methionyl-tRNA synthetase (MetRS), Zn-domain0Direct
Class II aaRS ABD-related0Direct
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain0Direct
Class II aaRS and biotin synthetases0Direct
Anticodon-binding domain of PheRS0Direct
GAD domain-like0Direct
Putative DNA-binding domain0Direct
Alpha-L RNA-binding motif0Direct
ACP-like0Direct
Nucleic acid-binding proteins0Direct
ValRS/IleRS/LeuRS editing domain0Direct
HD-domain/PDEase-like0Direct
YegP-like0Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0Direct
Translation proteins0Direct
TGS-like0Direct
Ribosomal protein L25-like0Direct
PheT/TilS domain0Direct
tRNA-binding arm0Direct
ThrRS/AlaRS common domain0Direct
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)0Direct
YbaK/ProRS associated domain0Direct
An anticodon-binding domain of class I aminoacyl-tRNA synthetases0Direct
S15/NS1 RNA-binding domain0Direct
C-terminal domain of ProRS0Direct
Acetyl-CoA synthetase-like0.00805Inherited
GST C-terminal domain-like0.9368Inherited
"Winged helix" DNA-binding domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    101353,55186
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    47323,47323
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    46955,55681
  • 46955 - Putative DNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    47616,52374
  • 47616 - GST C-terminal domain-like
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    101353,50447
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 50447 - Translation proteins
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    50447,55186
  • 50447 - Translation proteins
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    55681,55826
  • 55681 - Class II aaRS and biotin synthetases
  • 55826 - YbaK/ProRS associated domain
  • 0Direct
    52374,160113
  • 52374 - Nucleotidylyl transferase
  • 160113 - YegP-like
  • 0Direct
    47060,55681
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    46589,55681
  • 46589 - tRNA-binding arm
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    47060,52374
  • 47060 - S15/NS1 RNA-binding domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    50249,56037
  • 50249 - Nucleic acid-binding proteins
  • 56037 - PheT/TilS domain
  • 0Direct
    52374,50715
  • 52374 - Nucleotidylyl transferase
  • 50715 - Ribosomal protein L25-like
  • 0Direct
    52374,48163
  • 52374 - Nucleotidylyl transferase
  • 48163 - An anticodon-binding domain of class I aminoacyl-tRNA synthetases
  • 0Direct
    55681,55261
  • 55681 - Class II aaRS and biotin synthetases
  • 55261 - GAD domain-like
  • 0Direct
    47323,47060
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 47060 - S15/NS1 RNA-binding domain
  • 0Direct
    52374,50249
  • 52374 - Nucleotidylyl transferase
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    56037,46955
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 0Direct
    55190,52374
  • 55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    55681,54991
  • 55681 - Class II aaRS and biotin synthetases
  • 54991 - Anticodon-binding domain of PheRS
  • 0Direct
    52374,55174
  • 52374 - Nucleotidylyl transferase
  • 55174 - Alpha-L RNA-binding motif
  • 0Direct
    47060,47060
  • 47060 - S15/NS1 RNA-binding domain
  • 47060 - S15/NS1 RNA-binding domain
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    55186,55681
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    109604,47323
  • 109604 - HD-domain/PDEase-like
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    47323,50249
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    81271,55186
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    47323,46589
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 46589 - tRNA-binding arm
  • 0Direct
    57770,52374
  • 57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    46955,56037
  • 46955 - Putative DNA-binding domain
  • 56037 - PheT/TilS domain
  • 0Direct
    52954,64586
  • 52954 - Class II aaRS ABD-related
  • 64586 - C-terminal domain of ProRS
  • 0Direct
    55681,101353
  • 55681 - Class II aaRS and biotin synthetases
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0003377Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47616,52374,50715
  • 47616 - GST C-terminal domain-like
  • 52374 - Nucleotidylyl transferase
  • 50715 - Ribosomal protein L25-like
  • 0Direct
    50249,55681,55261
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 55261 - GAD domain-like
  • 0Direct
    52374,47323,50249
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    55186,55681,52954
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    46955,55681,54991
  • 46955 - Putative DNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 54991 - Anticodon-binding domain of PheRS
  • 0Direct
    47060,55681,52954
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    55681,52954,64586
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 64586 - C-terminal domain of ProRS
  • 0Direct
    52374,47323,47060
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 47060 - S15/NS1 RNA-binding domain
  • 0Direct
    50249,56037,46955
  • 50249 - Nucleic acid-binding proteins
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 0Direct
    50677,52374,47323
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    57770,52374,47323
  • 57770 - Methionyl-tRNA synthetase (MetRS), Zn-domain
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    81271,55186,55681
  • 81271 - TGS-like
  • 55186 - ThrRS/AlaRS common domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    47060,47060,55681
  • 47060 - S15/NS1 RNA-binding domain
  • 47060 - S15/NS1 RNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    101353,50447,55186
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 50447 - Translation proteins
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    55681,101353,55186
  • 55681 - Class II aaRS and biotin synthetases
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 55186 - ThrRS/AlaRS common domain
  • 0Direct
    56037,46955,55681
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    55681,101353,50447
  • 55681 - Class II aaRS and biotin synthetases
  • 101353 - Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
  • 50447 - Translation proteins
  • 0Direct
    47060,47060,47060
  • 47060 - S15/NS1 RNA-binding domain
  • 47060 - S15/NS1 RNA-binding domain
  • 47060 - S15/NS1 RNA-binding domain
  • 0Direct
    52374,47323,46589
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 46589 - tRNA-binding arm
  • 0Direct
    55190,52374,47323
  • 55190 - Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0Direct
    46955,56037,46955
  • 46955 - Putative DNA-binding domain
  • 56037 - PheT/TilS domain
  • 46955 - Putative DNA-binding domain
  • 0Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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