SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSNLEP00000000797 from Nomascus leucogenys 76_1.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSNLEP00000000797
Domain Number 1 Region: 300-491
Classification Level Classification E-value
Superfamily Hemopexin-like domain 6.28e-42
Family Hemopexin-like domain 0.00037
Further Details:      
 
Domain Number 2 Region: 121-276
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 6.15e-34
Family Matrix metalloproteases, catalytic domain 0.00017
Further Details:      
 
Domain Number 3 Region: 41-107
Classification Level Classification E-value
Superfamily PGBD-like 2.2e-05
Family MMP N-terminal domain 0.035
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSNLEP00000000797   Gene: ENSNLEG00000000684   Transcript: ENSNLET00000000847
Sequence length 518
Comment pep:known_by_projection supercontig:Nleu1.0:GL397421.1:1807814:1816961:-1 gene:ENSNLEG00000000684 transcript:ENSNLET00000000847 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MLAASIFRPTLLLCWLAAPWPTQPESLFHSRDRSDLEPSPLRQAKPIADLHAAQRFLSRY
GWSGVRAAWGPSPEGPPETPKGAALAEAVRRFQRANALPASGELDAQPRGSPDGGAAQAF
SKRTLSWRLLGEALSSQLSAAEQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFG
RGRHLGCPRAFDGSGQEFAHAWRLGDIHFDDDEHFTPPTSDMGISLLKVAVHEIGHVLGL
PHTYRTGSIMQPNYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVM
VRFSTYFFRNSWYWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFF
QGNQYWRYDSDKDQALTEDEQGKSYPKLISEGFPGIPSPLDTAFYDRRQKLIYFFKESLV
FAFDVNRNRVLNSYPKKITEVFPAIIPQNHPFRNIDSAYYSYAYNSIFFFKGNAYWKVVN
DKDKQQNSWLPANGLFPKKFISEKWFDVCDVHISTLNM
Download sequence
Identical sequences G1QIQ4
ENSNLEP00000000797

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