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Domain assignment for ENSNLEP00000008757 from Nomascus leucogenys 76_1.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSNLEP00000008757
Domain Number 1 Region: 284-477
Classification Level Classification E-value
Superfamily Hemopexin-like domain 2.22e-69
Family Hemopexin-like domain 0.000000576
Further Details:      
 
Domain Number 2 Region: 101-266
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 8.28e-59
Family Matrix metalloproteases, catalytic domain 0.0000000306
Further Details:      
 
Domain Number 3 Region: 33-97
Classification Level Classification E-value
Superfamily PGBD-like 2.2e-20
Family MMP N-terminal domain 0.00003
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Golgi lumen 2.224 18.39
cell surface 1.3 10.4
Golgi membrane 1.639 9.22
trans-Golgi network 1.766 9.22
neuron projection terminus 2.125 9.05
exocytic vesicle 2.03 8.34
vacuolar part 1.567 6.28
dendrite 1.582 5.69
host cell part 1.996 5.41
lysosomal membrane 1.946 5.05
Molecular Function IC (bits) H-Score
metallopeptidase activity 2.054 168.98
endopeptidase activity 1.571 151.3
zinc ion binding 1.527 42.04
cytokine receptor binding 1.974 16.02
growth factor receptor binding 2.188 16.02
enzyme activator activity 1.431 14.69
integrin binding 1.56 12.29
fibronectin binding 2.165 10.75
serine hydrolase activity 1.589 10.26
peptide transporter activity 1.665 9.96

Protein sequence

External link(s) Protein: ENSNLEP00000008757   Gene: ENSNLEG00000007178   Transcript: ENSNLET00000009175
Sequence length 477
Comment pep:known_by_projection supercontig:Nleu1.0:GL397262.1:35948457:35956266:-1 gene:ENSNLEG00000007178 transcript:ENSNLET00000009175 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKSLPILLFLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGQFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPAKCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELYLISSFWPSLPSGVDAAYEVTSKDLVFVFKGSQF
WAIRGNEVQAGYPRGIHTLGFPPTVRKIDAAISDKEKKKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
Download sequence
Identical sequences G1R6D5
ENSNLEP00000008757 ENSNLEP00000008757

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