SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSNLEP00000008760 from Nomascus leucogenys 76_1.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSNLEP00000008760
Domain Number 1 Region: 277-470
Classification Level Classification E-value
Superfamily Hemopexin-like domain 1.44e-67
Family Hemopexin-like domain 0.00000148
Further Details:      
 
Domain Number 2 Region: 103-265
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 6.88e-58
Family Matrix metalloproteases, catalytic domain 0.0000000976
Further Details:      
 
Domain Number 3 Region: 22-97
Classification Level Classification E-value
Superfamily PGBD-like 7.06e-21
Family MMP N-terminal domain 0.00099
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSNLEP00000008760   Gene: ENSNLEG00000007183   Transcript: ENSNLET00000009178
Sequence length 470
Comment pep:known_by_projection supercontig:Nleu1.0:GL397262.1:35982175:35994473:-1 gene:ENSNLEG00000007183 transcript:ENSNLET00000009178 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKFLLILLLQATASGALPLNSSTSLEKNDVLFGERYLERFYGLEMNKLSMTKMKYSGNLM
KEKIQEMQQFLGLKVTGQLDTATLEMMHAPRCGVPDVHHLREMSGRPVWRKHYITYRINN
YTPDMNREDVDNTIRKAFQVWSNVTPLKFSKIKTGVADILVVFARGAHGDFHAFDGKGGI
LAHAFGPGSGIGGDAHFDDDEFWTTHSEGTNLFLTAVHEIGHSLGLGHSSDPKAIMFPTY
KYVDINTFRLSADDIRGIQSLYGYPKENQPLPNPDNSEPALCDPNLSFDAVTRVGDKIFF
FKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRP
EPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVGNQYWRYNERTQMMDPGYPKLITK
NFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRVTKTLKSNSWFDC
Download sequence
Identical sequences G1R6D8
ENSNLEP00000008760 ENSNLEP00000008760

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