SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSNLEP00000012434 from Nomascus leucogenys 76_1.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSNLEP00000012434
Domain Number 1 Region: 292-488
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.84e-69
Family Hemopexin-like domain 7.46e-06
Further Details:      
 
Domain Number 2 Region: 80-246
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 8.2e-57
Family Matrix metalloproteases, catalytic domain 1.14e-07
Further Details:      
 
Domain Number 3 Region: 1-63
Classification Level Classification E-value
Superfamily PGBD-like 4.87e-19
Family MMP N-terminal domain 0.0041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07
Cellular Component IC (bits) H-Score
brush border 1.48 22.54
Golgi lumen 2.239 12.24
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11

Protein sequence

External link(s) Protein: ENSNLEP00000012434   Gene: ENSNLEG00000010203   Transcript: ENSNLET00000013041
Sequence length 564
Comment pep:known_by_projection supercontig:Nleu1.0:GL397356.1:6817320:6847828:1 gene:ENSNLEG00000010203 transcript:ENSNLET00000013041 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
QNWLKSYGYLLPYDSRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGV
PDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPL
TFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSD
EPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQG
IQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICD
GNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFV
FFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSE
ERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRN
ILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYT
IFQFKNKTGPQPVTYYKRPVQEWV
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Identical sequences G1RGT4
ENSNLEP00000012434 ENSNLEP00000012434

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