SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSNLEP00000012434 from Nomascus leucogenys 76_1.0

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSNLEP00000012434
Domain Number 1 Region: 292-488
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.84e-69
Family Hemopexin-like domain 0.00000746
Further Details:      
 
Domain Number 2 Region: 80-246
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 8.2e-57
Family Matrix metalloproteases, catalytic domain 0.000000114
Further Details:      
 
Domain Number 3 Region: 1-63
Classification Level Classification E-value
Superfamily PGBD-like 4.87e-19
Family MMP N-terminal domain 0.0041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSNLEP00000012434   Gene: ENSNLEG00000010203   Transcript: ENSNLET00000013041
Sequence length 564
Comment pep:known_by_projection supercontig:Nleu1.0:GL397356.1:6817320:6847828:1 gene:ENSNLEG00000010203 transcript:ENSNLET00000013041 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
QNWLKSYGYLLPYDSRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGV
PDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPL
TFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSD
EPWTLGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQG
IQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICD
GNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFV
FFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSE
ERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRN
ILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILSLCILVLVYT
IFQFKNKTGPQPVTYYKRPVQEWV
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Identical sequences G1RGT4
ENSNLEP00000012434 ENSNLEP00000012434

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