SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSCAFP00000011799 from Canis familiaris 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSCAFP00000011799
Domain Number 1 Region: 301-497
Classification Level Classification E-value
Superfamily Hemopexin-like domain 7.59e-69
Family Hemopexin-like domain 7.46e-06
Further Details:      
 
Domain Number 2 Region: 89-255
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 7.34e-57
Family Matrix metalloproteases, catalytic domain 1.07e-07
Further Details:      
 
Domain Number 3 Region: 7-72
Classification Level Classification E-value
Superfamily PGBD-like 6.75e-20
Family MMP N-terminal domain 0.0041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSCAFP00000011799   Gene: ENSCAFG00000007966   Transcript: ENSCAFT00000012740
Sequence length 573
Comment pep:known_by_projection chromosome:CanFam3.1:24:24233418:24255725:1 gene:ENSCAFG00000007966 transcript:ENSCAFT00000012740 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MRPSLSCVFQNWLKSYGYLLPYDSRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIE
WMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAF
DVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGI
GGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNF
KLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPST
PGAKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAA
YERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFK
GERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKL
SVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILS
LCILVLVYTIFQFKNKAGPQPVTYYKRPVQEWV
Download sequence
Identical sequences F1Q270
ENSCAFP00000011799 ENSCAFP00000011799

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