SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSCAFP00000011799 from Canis familiaris 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSCAFP00000011799
Domain Number 1 Region: 301-497
Classification Level Classification E-value
Superfamily Hemopexin-like domain 7.59e-69
Family Hemopexin-like domain 0.00000746
Further Details:      
 
Domain Number 2 Region: 89-255
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 7.34e-57
Family Matrix metalloproteases, catalytic domain 0.000000107
Further Details:      
 
Domain Number 3 Region: 7-72
Classification Level Classification E-value
Superfamily PGBD-like 6.75e-20
Family MMP N-terminal domain 0.0041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54
Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58

Protein sequence

External link(s) Protein: ENSCAFP00000011799   Gene: ENSCAFG00000007966   Transcript: ENSCAFT00000012740
Sequence length 573
Comment pep:known_by_projection chromosome:CanFam3.1:24:24233418:24255725:1 gene:ENSCAFG00000007966 transcript:ENSCAFT00000012740 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MRPSLSCVFQNWLKSYGYLLPYDSRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIE
WMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAF
DVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGI
GGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNF
KLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPST
PGAKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAA
YERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFK
GERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKL
SVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILS
LCILVLVYTIFQFKNKAGPQPVTYYKRPVQEWV
Download sequence
Identical sequences F1Q270
ENSCAFP00000011799 ENSCAFP00000011799

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