SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Domain assignment for ENSCAFP00000011799 from Canis familiaris 76_3.1

Domain architecture


Domain assignment details

(
show help)
Strong hits

Sequence:  ENSCAFP00000011799
Domain Number 1 Region: 301-497
Classification Level Classification E-value
Superfamily Hemopexin-like domain 7.59e-69
Family Hemopexin-like domain 0.00000746
Further Details:      
 
Domain Number 2 Region: 89-255
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 7.34e-57
Family Matrix metalloproteases, catalytic domain 0.000000107
Further Details:      
 
Domain Number 3 Region: 7-72
Classification Level Classification E-value
Superfamily PGBD-like 6.75e-20
Family MMP N-terminal domain 0.0041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

(show help)

Cellular Component IC (bits) H-Score
Golgi lumen 2.224 18.39
cell surface 1.3 10.4
Golgi membrane 1.639 9.22
trans-Golgi network 1.766 9.22
neuron projection terminus 2.125 9.05
exocytic vesicle 2.03 8.34
vacuolar part 1.567 6.28
dendrite 1.582 5.69
host cell part 1.996 5.41
lysosomal membrane 1.946 5.05
Molecular Function IC (bits) H-Score
metallopeptidase activity 2.054 168.98
endopeptidase activity 1.571 151.3
zinc ion binding 1.527 42.04
cytokine receptor binding 1.974 16.02
growth factor receptor binding 2.188 16.02
enzyme activator activity 1.431 14.69
integrin binding 1.56 12.29
fibronectin binding 2.165 10.75
serine hydrolase activity 1.589 10.26
peptide transporter activity 1.665 9.96

Protein sequence

External link(s) Protein: ENSCAFP00000011799   Gene: ENSCAFG00000007966   Transcript: ENSCAFT00000012740
Sequence length 573
Comment pep:known_by_projection chromosome:CanFam3.1:24:24233418:24255725:1 gene:ENSCAFG00000007966 transcript:ENSCAFT00000012740 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MRPSLSCVFQNWLKSYGYLLPYDSRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIE
WMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAF
DVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGI
GGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNF
KLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPST
PGAKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAA
YERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFK
GERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKL
SVEPGYPRNILRDWMGCNQKEVERRKERRLPQDDVDIMVTINDVPGSVNAVAVVIPCILS
LCILVLVYTIFQFKNKAGPQPVTYYKRPVQEWV
Download sequence
Identical sequences F1Q270
ENSCAFP00000011799 ENSCAFP00000011799

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]