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Domain assignment for ENSCAFP00000030466 from Canis familiaris 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSCAFP00000030466
Domain Number 1 Region: 97-258
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 2.42e-54
Family Matrix metalloproteases, catalytic domain 0.000000403
Further Details:      
 
Domain Number 2 Region: 21-92
Classification Level Classification E-value
Superfamily PGBD-like 1.73e-21
Family MMP N-terminal domain 0.0011
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
cell surface 1.3 10.4
Golgi membrane 1.639 9.22
trans-Golgi network 1.766 9.22
neuron projection terminus 2.125 9.05
exocytic vesicle 2.03 8.34
vacuolar part 1.567 6.28
dendrite 1.582 5.69
host cell part 1.996 5.41
lysosomal membrane 1.946 5.05
endocytic vesicle 1.532 4.85
Molecular Function IC (bits) H-Score
metallopeptidase activity 2.054 168.98
endopeptidase activity 1.571 151.3
zinc ion binding 1.527 42.04
cytokine receptor binding 1.974 16.02
growth factor receptor binding 2.188 16.02
enzyme activator activity 1.431 14.69
integrin binding 1.56 12.29
fibronectin binding 2.165 10.75
serine hydrolase activity 1.589 10.26
peptide transporter activity 1.665 9.96

Protein sequence

External link(s) Protein: ENSCAFP00000030466   Gene: ENSCAFG00000015080   Transcript: ENSCAFT00000035230
Sequence length 267
Comment pep:known chromosome:CanFam3.1:5:29187902:29194899:1 gene:ENSCAFG00000015080 transcript:ENSCAFT00000035230 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MWPAVLCALCLLPSCLALPLPREAGGMSEPQWKQAQDYLKRFYPSDSKTRDADSFKTKLK
EMQKFFRLPVTGILNSRTIEIMQKPRCGVPDVAHFSLFPNRPKWTSEVITYRIASYTPDL
PRFRVNQLVAKALAMWSKEIPLSFRRVPRGTADIMIGFARGAHGDYYPFDGPGNILAHAF
APGPDLGGDAHFDEDERWTDGSRIGINFLIAATHELGHSLGLGHSSDPDAVMYPTYSIRD
SKSFKLSQDDIEGIQKLYVLQDNPQQR
Download sequence
Identical sequences E2R288
9615.ENSCAFP00000030466 ENSCAFP00000022222 ENSCAFP00000030466

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