SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSGGOP00000008521 from Gorilla gorilla 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSGGOP00000008521
Domain Number 1 Region: 273-465
Classification Level Classification E-value
Superfamily Hemopexin-like domain 6.8e-62
Family Hemopexin-like domain 0.00000111
Further Details:      
 
Domain Number 2 Region: 101-261
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.39e-54
Family Matrix metalloproteases, catalytic domain 0.00000558
Further Details:      
 
Domain Number 3 Region: 18-96
Classification Level Classification E-value
Superfamily PGBD-like 8.95e-21
Family MMP N-terminal domain 0.00059
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSGGOP00000008521   Gene: ENSGGOG00000008717   Transcript: ENSGGOT00000008755
Sequence length 513
Comment pep:known_by_projection chromosome:gorGor3.1:11:100247462:100262528:-1 gene:ENSGGOG00000008717 transcript:ENSGGOT00000008755 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKRLLLLFLFFITFSSPFPSVRMTENEDNVQLAQAYLNQFYSLEIEGNHLVQSKNRSLID
DKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTLPGWRKYNLTYRIINYTP
DMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPLGVLG
HAFPPGPGLGGDTHFDEDENWTKDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFPNYVS
LDPRKYPLSQDDINGIQSIYGGLPKVPAKPKEPTIPHACDPDLTFDAITTFRREVMFFKG
RHLWRIYYDITDVEFELIASFWPSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDY
PKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPG
ISIRVDAAFQYKGFFYFSRGSKQFEYDIKTKNITRIVRTNTWFQCKEPKNSSFGFDINKE
KAHSGGIKILYHKSLSLFIFGIVHLLKNTSIYQ
Download sequence
Identical sequences G3R045
ENSGGOP00000008521 ENSGGOP00000008521

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