SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSGGOP00000017139 from Gorilla gorilla 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSGGOP00000017139
Domain Number 1 Region: 278-471
Classification Level Classification E-value
Superfamily Hemopexin-like domain 2.49e-67
Family Hemopexin-like domain 1.25e-06
Further Details:      
 
Domain Number 2 Region: 102-265
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 3.67e-57
Family Matrix metalloproteases, catalytic domain 6.81e-08
Further Details:      
 
Domain Number 3 Region: 22-97
Classification Level Classification E-value
Superfamily PGBD-like 4.71e-20
Family MMP N-terminal domain 0.0008
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.68
endopeptidase activity 1.539 149.06
zinc ion binding 1.658 43.63
integrin binding 1.752 16.89
cytokine receptor binding 2.034 15.07
growth factor receptor binding 1.996 15.07
enzyme activator activity 1.402 14.46
amide binding 1.714 13.22
collagen binding 1.837 10.42
protein complex binding 1.49 7.68
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.15 9.58
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.9
clathrin-coated vesicle 1.877 7.9
dendrite 1.544 7.13
synapse part 1.52 5.81

Protein sequence

External link(s) Protein: ENSGGOP00000017139   Gene: ENSGGOG00000015496   Transcript: ENSGGOT00000033003
Sequence length 471
Comment pep:known_by_projection chromosome:gorGor3.1:11:100424999:100437218:-1 gene:ENSGGOG00000015496 transcript:ENSGGOT00000033003 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLM
KEKIQEMQHFLGLKVTGQLDTSTLEMMRAPRCGVPDVHHFREMPGGPVWRKHYITYRINN
YTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGI
LAHAFGPGSGIGGDAHFDEDEFWTTHSGGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPT
YKYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPNNSEPALCDPNLSFDAVTTVGNKIF
FFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLR
PEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKVIT
KNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
Download sequence
Identical sequences G3RMX3
ENSGGOP00000017139 ENSGGOP00000015120

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