SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSGGOP00000021432 from Gorilla gorilla 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSGGOP00000021432
Domain Number 1 Region: 336-532
Classification Level Classification E-value
Superfamily Hemopexin-like domain 1.7e-70
Family Hemopexin-like domain 7.34e-06
Further Details:      
 
Domain Number 2 Region: 119-294
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 2.22e-55
Family Matrix metalloproteases, catalytic domain 5.43e-08
Further Details:      
 
Domain Number 3 Region: 29-106
Classification Level Classification E-value
Superfamily PGBD-like 5.81e-21
Family MMP N-terminal domain 0.0023
Further Details:      
 

Most Informative Gene Ontologies

Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.68
endopeptidase activity 1.539 149.06
zinc ion binding 1.658 43.63
integrin binding 1.752 16.89
cytokine receptor binding 2.034 15.07
growth factor receptor binding 1.996 15.07
enzyme activator activity 1.402 14.46
amide binding 1.714 13.22
collagen binding 1.837 10.42
protein complex binding 1.49 7.68
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.15 9.58
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.9
clathrin-coated vesicle 1.877 7.9
dendrite 1.544 7.13
synapse part 1.52 5.81
Biological Process IC (bits) H-Score
multicellular organismal macromolecule metabolic process 2.096 51.92
response to light stimulus 1.445 44.78
regulation of cytokine production 1.55 43.33
protein processing 1.807 42.16
proteolysis 1.342 38.76
peptide metabolic process 1.567 38.1
regulation of systemic arterial blood pressure 1.951 27.4
multi-organism behavior 1.851 26.92
interspecies interaction between organisms 1.592 26.41
modification by symbiont of host morphology or physiology 2.008 26.41

Protein sequence

External link(s) Protein: ENSGGOP00000021432   Gene: ENSGGOG00000027756   Transcript: ENSGGOT00000031736
Sequence length 607
Comment pep:known_by_projection chromosome:gorGor3.1:8:86761286:87063492:-1 gene:ENSGGOG00000027756 transcript:ENSGGOT00000031736 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MILLTFSTGRRLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYGYLPPTDPRM
SVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRY
ALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKR
DVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDL
FLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPT
RPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKPNICDGNFNTLAILRREMFVF
KDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSDGNFVFFKGNKYWVFKDTTLQ
PGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITVW
KGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMGCDGPTDRVK
EGHSPPDDVDIVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYCK
RSMQEWV
Download sequence
Identical sequences F6XPY4 G3S039 G7PC63 H2QWE3 P51512
ENSP00000286614 9544.ENSMMUP00000017328 9598.ENSPTRP00000034899 9606.ENSP00000286614 ENSPTRP00000034899 ENSP00000286614 ENSMMUP00000017328 ENSGGOP00000021432 ENSGGOP00000021432 ENSPTRP00000034899 ENSMMUP00000017328 gi|13027802|ref|NP_005932.2|

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