SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSGGOP00000027282 from Gorilla gorilla 76_3.1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSGGOP00000027282
Domain Number 1 Region: 48-182
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 3.67e-44
Family Matrix metalloproteases, catalytic domain 1.64e-06
Further Details:      
 
Domain Number 2 Region: 1-35
Classification Level Classification E-value
Superfamily PGBD-like 5.02e-15
Family MMP N-terminal domain 0.00055
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07
Cellular Component IC (bits) H-Score
brush border 1.48 22.54
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11
dendrite 1.547 7.03

Protein sequence

External link(s) Protein: ENSGGOP00000027282   Gene: ENSGGOG00000008869   Transcript: ENSGGOT00000027023
Sequence length 182
Comment pep:known_by_projection chromosome:gorGor3.1:11:100357453:100359416:-1 gene:ENSGGOG00000008869 transcript:ENSGGOT00000027023 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
KLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVSVCPLRGTLAGSTYRIENYTPDLPQ
VDQPLRKPSNWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPG
IGGDAHFDEDERWYNLYRVAAHELGHSLGLSHSTDIGALMYPSYLQDVQLAQDDIDGIQA
IY
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Identical sequences G3SGP5
ENSGGOP00000027282

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