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Domain assignment for ENSP00000441485 from Homo sapiens 76_38

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000441485
Domain Number 1 Region: 24-96
Classification Level Classification E-value
Superfamily PGBD-like 3.92e-21
Family MMP N-terminal domain 0.00012
Further Details:      
 
Domain Number 2 Region: 102-178
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 5.87e-20
Family Matrix metalloproteases, catalytic domain 0.0000207
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
cell surface 1.3 10.4
Golgi membrane 1.639 9.22
trans-Golgi network 1.766 9.22
neuron projection terminus 2.125 9.05
exocytic vesicle 2.03 8.34
vacuolar part 1.567 6.28
dendrite 1.582 5.69
host cell part 1.996 5.41
lysosomal membrane 1.946 5.05
endocytic vesicle 1.532 4.85
Molecular Function IC (bits) H-Score
metallopeptidase activity 2.054 168.98
endopeptidase activity 1.571 151.3
zinc ion binding 1.527 42.04
cytokine receptor binding 1.974 16.02
growth factor receptor binding 2.188 16.02
enzyme activator activity 1.431 14.69
integrin binding 1.56 12.29
fibronectin binding 2.165 10.75
serine hydrolase activity 1.589 10.26
peptide transporter activity 1.665 9.96

Protein sequence

External link(s) Protein: ENSP00000441485   Gene: ENSG00000166670   Transcript: ENST00000539681
Sequence length 181
Comment pep:novel chromosome:GRCh38:11:102778669:102780628:-1 gene:ENSG00000166670 transcript:ENST00000539681 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIV
KKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNY
TPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKGHSLAHAYPPGPGLY
G
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Identical sequences F5GYX7
ENSP00000441485 ENSP00000441485

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