SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSDORP00000012970 from Dipodomys ordii 76_1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSDORP00000012970
Domain Number 1 Region: 106-268
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.07e-55
Family Matrix metalloproteases, catalytic domain 0.0000000678
Further Details:      
 
Domain Number 2 Region: 276-349
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.84e-23
Family Hemopexin-like domain 0.000011
Further Details:      
 
Domain Number 3 Region: 29-101
Classification Level Classification E-value
Superfamily PGBD-like 3.45e-19
Family MMP N-terminal domain 0.00056
Further Details:      
 
Domain Number 4 Region: 403-442
Classification Level Classification E-value
Superfamily Hemopexin-like domain 0.0000017
Family Hemopexin-like domain 0.00028
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSDORP00000012970   Gene: ENSDORG00000013795   Transcript: ENSDORT00000013795
Sequence length 448
Comment pep:known_by_projection genescaffold:dipOrd1:GeneScaffold_3145:6173:15493:-1 gene:ENSDORG00000013795 transcript:ENSDORT00000013795 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MHPGVLAAFFFLSWAHCRSLPLPSGDDDSDLSEEDLQFAEHYLKSYYHPRNLAGILKKSA
AGSMVERLREMQSFFGLEVTGQLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSNMNLTY
RIVNYTPDMTHSEVEKSFKKAFKVWSDVTPLNFTRIHDGTADIMISFGTKEHGDFYPFDG
PSGLLAHAFPPGPNYGGDAHFDDDETTSTSKGYNLFLVAAHEFGHSLGLDHSKDPGALMF
PIYTYTGKNHFMLPEDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPALSLDAITSLRGETM
IFKDRFFWRLHPQQVDAELFLTKSFWPELPNRVDAAYEHPSRDLIFIFRXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYDDINHIMDKDYPRLIE
EEFPGIGDKVDAVYEKNLYLFFQWTHTV
Download sequence
Identical sequences ENSDORP00000012970 ENSDORP00000012970

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