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Domain assignment for ENSDORP00000012970 from Dipodomys ordii 76_1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSDORP00000012970
Domain Number 1 Region: 106-268
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.07e-55
Family Matrix metalloproteases, catalytic domain 0.0000000678
Further Details:      
 
Domain Number 2 Region: 276-349
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.84e-23
Family Hemopexin-like domain 0.000011
Further Details:      
 
Domain Number 3 Region: 29-101
Classification Level Classification E-value
Superfamily PGBD-like 3.45e-19
Family MMP N-terminal domain 0.00056
Further Details:      
 
Domain Number 4 Region: 403-442
Classification Level Classification E-value
Superfamily Hemopexin-like domain 0.0000017
Family Hemopexin-like domain 0.00028
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 2.041 167.45
endopeptidase activity 1.576 149.51
zinc ion binding 1.567 42.55
growth factor receptor binding 2.175 16
cytokine receptor binding 1.96 16
enzyme activator activity 1.426 14.68
integrin binding 1.558 12.31
fibronectin binding 2.151 10.88
serine hydrolase activity 1.585 10.2
peptide transporter activity 1.652 9.95
Cellular Component IC (bits) H-Score
Golgi lumen 2.204 18.78
brush border 1.374 15.66
neuron projection terminus 2.128 10.01
exocytic vesicle 1.966 9.77
Golgi membrane 1.599 9.32
trans-Golgi network 1.734 9.32
vacuolar part 1.526 6.31
host intracellular part 1.994 5.4
dendrite 1.581 5.09
lysosomal membrane 1.908 5.02

Protein sequence

External link(s) Protein: ENSDORP00000012970   Gene: ENSDORG00000013795   Transcript: ENSDORT00000013795
Sequence length 448
Comment pep:known_by_projection genescaffold:dipOrd1:GeneScaffold_3145:6173:15493:-1 gene:ENSDORG00000013795 transcript:ENSDORT00000013795 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MHPGVLAAFFFLSWAHCRSLPLPSGDDDSDLSEEDLQFAEHYLKSYYHPRNLAGILKKSA
AGSMVERLREMQSFFGLEVTGQLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSNMNLTY
RIVNYTPDMTHSEVEKSFKKAFKVWSDVTPLNFTRIHDGTADIMISFGTKEHGDFYPFDG
PSGLLAHAFPPGPNYGGDAHFDDDETTSTSKGYNLFLVAAHEFGHSLGLDHSKDPGALMF
PIYTYTGKNHFMLPEDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPALSLDAITSLRGETM
IFKDRFFWRLHPQQVDAELFLTKSFWPELPNRVDAAYEHPSRDLIFIFRXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYDDINHIMDKDYPRLIE
EEFPGIGDKVDAVYEKNLYLFFQWTHTV
Download sequence
Identical sequences ENSDORP00000012970 ENSDORP00000012970

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