SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMICP00000013180 from Microcebus murinus 76_1

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMICP00000013180
Domain Number 1 Region: 100-208
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.34e-29
Family Matrix metalloproteases, catalytic domain 9.21e-06
Further Details:      
 
Domain Number 2 Region: 32-95
Classification Level Classification E-value
Superfamily PGBD-like 1.19e-20
Family MMP N-terminal domain 0.0003
Further Details:      
 
Domain Number 3 Region: 272-300
Classification Level Classification E-value
Superfamily Hemopexin-like domain 5.36e-06
Family Hemopexin-like domain 0.0013
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSMICP00000013180   Gene: ENSMICG00000014462   Transcript: ENSMICT00000014459
Sequence length 300
Comment pep:novel genescaffold:micMur1:GeneScaffold_4897:31952:40625:-1 gene:ENSMICG00000014462 transcript:ENSMICT00000014459 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MFCLKTLPLLLLLHMELSKAFPVPSEGRNAKIVQDYLEKFYRLPSNQYRTARKNSASMVV
EKLKEMQRFFGLNVTGKPDAETLEVMEKPRCGVPDSSSFMITPGSPKWEHTNVTYRIISH
TQQLSVAEVGAAFEKAFKLWSGASPLTFTRISQGEADIKIAFVQRDHGDNSPFDGPNGIL
AHAFQPGPGIGGDVHFDAEETWTTNFNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXPSNNPIQPTGPSTPMACDPRLTFDAITTLRGEIFFFKD
Download sequence
Identical sequences ENSMICP00000013180 ENSMICP00000013180

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