SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMUSP00000034243 from Mus musculus 76_38

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMUSP00000034243
Domain Number 1 Region: 358-555
Classification Level Classification E-value
Superfamily Hemopexin-like domain 8.63e-69
Family Hemopexin-like domain 1e-05
Further Details:      
 
Domain Number 2 Region: 127-300
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 5.34e-52
Family Matrix metalloproteases, catalytic domain 6.97e-07
Further Details:      
 
Domain Number 3 Region: 40-112
Classification Level Classification E-value
Superfamily PGBD-like 2.51e-20
Family MMP N-terminal domain 0.0038
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSMUSP00000034243   Gene: ENSMUSG00000031790   Transcript: ENSMUST00000034243
Sequence length 657
Comment pep:known chromosome:GRCm38:8:95352268:95374293:1 gene:ENSMUSG00000031790 transcript:ENSMUST00000034243 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MGSDRSALGRPGCTGSCLSSRASLLPLLLVLLDCLGHGTASKDAEVYAAENWLRLYGYLP
QPSRHMSTMRSAQILASALAEMQSFYGIPVTGVLDEETKTWMKRPRCGVPDQFGVHVKAN
LRRRRKRYTLTGKAWNNYHLTFSIQNYTEKLGWYNSMEAVRRAFQVWEQVTPLVFQEVSY
DDIRLRRRAEADIMVLFASGFHGDSSPFDGVGGFLAHAYFPGPGLGGDTHFDADEPWTFS
STDLHGISLFLVAVHELGHALGLEHSSNPSAIMAPFYQWMDTDNFQLPEDDLRGIQQLYG
SPDGKPQPTRPLPTVRPRRPGRPDHQPPRPPQPPHPGGKPERPPKPGPPPQPRATERPDQ
YGPNICDGNFDTVAVLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGNISAAYE
RQDGHFVFFKGNRYWLFREANLEPGYPQPLSSYGTDIPYDRIDTAIWWEPTGHTFFFQAD
RYWRFNEETQHGDPGYPKPISVWQGIPTSPKGAFLSNDAAYTYFYKGTKYWKFNNERLRM
EPGHPKSILRDFMGCQEHVEPRSRWPDVARPPFNPNGGAEPEADGDSKEENAGDKDEGSR
VVVQMEEVVRTVNVVMVLVPLLLLLCILGLAFALVQMQRKGAPRMLLYCKRSLQEWV
Download sequence
Identical sequences O54732
ENSMUSP00000034243 ENSMUSP00000034243 ENSMUSP00000034243 10090.ENSMUSP00000034243

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