SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMUSP00000034488 from Mus musculus 76_38

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMUSP00000034488
Domain Number 1 Region: 283-476
Classification Level Classification E-value
Superfamily Hemopexin-like domain 3.14e-67
Family Hemopexin-like domain 6.16e-07
Further Details:      
 
Domain Number 2 Region: 102-266
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 3.08e-58
Family Matrix metalloproteases, catalytic domain 2.84e-07
Further Details:      
 
Domain Number 3 Region: 33-97
Classification Level Classification E-value
Superfamily PGBD-like 6.28e-21
Family MMP N-terminal domain 0.00012
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
growth factor receptor binding 1.996 15.08
cytokine receptor binding 2.034 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
clathrin-coated vesicle 1.877 7.82
coated vesicle 1.745 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSMUSP00000034488   Gene: ENSMUSG00000047562   Transcript: ENSMUST00000034488
Sequence length 476
Comment pep:known chromosome:GRCm38:9:7502352:7510238:1 gene:ENSMUSG00000047562 transcript:ENSMUST00000034488 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MEPLAILALLSLPICSAYPLHGAVTQGHPSMDLAQQYLEKYYNFKKNEKQIFKRKDSSPV
VKKIQEMQKFLGLEMTGKLDSNTMELMHKPRCGVPDVGGFSTFPGSPKWRKSHITYRIVN
YTPDLPRQSVDSAIEKALKVWEEVTPLTFSRISEGEADIMISFAVGEHGDFYPFDGPGQS
LAHAYPPGPGFYGDVHFDDDEKWTLAPSGTNLFLVAAHELGHSLGLFHSDKKESLMYPVY
RFSTSPANFHLSQDDIEGIQSLYGAGPSSDATVVPVLSVSPRPETPDKCDPALSFDSVST
LRGEVLFFKDRYFWRRSHWNPEPEFHLISAFWPTLPSDLDAAYEAHNTDSVLIFKGSQFW
AVRGNEVQAGYPKGIHTLGFPPTVKKIDAAVFEKEKKKTYFFVGDKYWRFDETRHVMDKG
FPRQITDDFPGIEPQVDAVLHEFGFFYFFRGSSQFEFDPNARTVTHILKSNSWLLC
Download sequence
Identical sequences A1L3D0 O55123
ENSMUSP00000034488 ENSMUSP00000034488 ENSMUSP00000034488 10090.ENSMUSP00000034488

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