SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSMUSP00000117469 from Mus musculus 76_38

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSMUSP00000117469
Domain Number 1 Region: 315-506
Classification Level Classification E-value
Superfamily Hemopexin-like domain 3.27e-62
Family Hemopexin-like domain 0.000000676
Further Details:      
 
Domain Number 2 Region: 119-179,207-302
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 4.53e-48
Family Matrix metalloproteases, catalytic domain 0.00000791
Further Details:      
 
Domain Number 3 Region: 46-110
Classification Level Classification E-value
Superfamily PGBD-like 5.18e-19
Family MMP N-terminal domain 0.00066
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSMUSP00000117469   Gene: ENSMUSG00000070323   Transcript: ENSMUST00000151853
Sequence length 551
Comment pep:putative chromosome:GRCm38:9:7571458:7581391:1 gene:ENSMUSG00000070323 transcript:ENSMUST00000151853 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPYKQKQALTEETGMKCLLSLMVNFITLSAAFPPDRKDKNEENNQLAQAYLNQFYSLEIE
GSHFVQSKNRSLFDGKLREMQAFFGLTVTGKLDSDTLAIMKVPRCGVPDVGQYGYTLPGW
RKYSLTYRIMNYTPDMTPADVDEAIQKALQVWSKVTPLTFTRISKGVADIMIAFRTGGKA
CSEGSDFFEDHRELTYLPINCLSVHGWCPRHFDGPLGVLGHAFPPGLGLGGDTHFDEDET
WIAKDGEGFNLFLVAAHEFGHSLGLSHSNDQTALMFPNYISLDPSKYPLSQDDIDGIQSI
YGSPPKVTTKPSGNSEPHACDPTLTFDAITTFRREVMFFKGRHLWRVYSDIAGAEFEFID
SFWPSLPADLQAAYESPRDELLVFKDENFWVIRGYSVLPGYPKSIHTLGFPRRVKKIDAA
VCDHDTRKTFFFVGIWCWRYDEMAQAMDRGFPQRIIKCFPGIRLRVDAVFQHNGFLYFFH
GSRQFEYDMKAKNITQVIKTNSWFLCNEPLNASFNVSVKGKANSIGTVILHHKRLSLLTF
SIVHVLTKTYN
Download sequence
Identical sequences D3YV89
ENSMUSP00000091423 ENSMUSP00000117469 ENSMUSP00000113231 ENSMUSP00000091423 10090.ENSMUSP00000117469

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