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Domain assignment for NP_000116.2.87134 from NCBI 2017_08 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  NP_000116.2.87134
Domain Number 1 Region: 315-547
Classification Level Classification E-value
Superfamily Nuclear receptor ligand-binding domain 5.11e-71
Family Nuclear receptor ligand-binding domain 0.000000000573
Further Details:      
 
Domain Number 2 Region: 183-262
Classification Level Classification E-value
Superfamily Glucocorticoid receptor-like (DNA-binding domain) 1.43e-28
Family Nuclear receptor 0.0000153
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) NP_000116.2.87134
Sequence length 595
Comment estrogen receptor isoform 1 [Homo sapiens]; AA=GCF_000306695.2; RF=na; TAX=9606; STAX=9606; NAME=Homo sapiens; AL=Chromosome; RT=Major
Sequence
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Download sequence
Identical sequences G4XH65 P03372
ENSP00000206249 ENSP00000342630 ENSP00000387500 ENSP00000405330 ENSP00000206249 ENSP00000342630 ENSP00000387500 ENSP00000405330 9606.ENSP00000206249 NP_000116.2.87134 NP_000116.2.92137 NP_001116212.1.87134 NP_001116212.1.92137 NP_001116213.1.87134 NP_001116213.1.92137 NP_001116214.1.87134 NP_001116214.1.92137 XP_011533845.1.92137 XP_011533846.1.92137 XP_011533847.1.92137 XP_016865865.1.92137 XP_016865866.1.92137 XP_016865867.1.92137 XP_016865868.1.92137 XP_016865869.1.92137 XP_016865870.1.92137 HR4801 ENSP00000342630 gi|170295800|ref|NP_001116212.1| gi|170295802|ref|NP_001116213.1| gi|170295804|ref|NP_001116214.1| gi|62821794|ref|NP_000116.2|

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