SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSPPYP00000004363 from Pongo abelii 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSPPYP00000004363
Domain Number 1 Region: 284-477
Classification Level Classification E-value
Superfamily Hemopexin-like domain 5.89e-69
Family Hemopexin-like domain 6.16e-07
Further Details:      
 
Domain Number 2 Region: 101-266
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 8.28e-59
Family Matrix metalloproteases, catalytic domain 3.06e-08
Further Details:      
 
Domain Number 3 Region: 23-97
Classification Level Classification E-value
Superfamily PGBD-like 2.04e-20
Family MMP N-terminal domain 4.52e-05
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07
Cellular Component IC (bits) H-Score
brush border 1.48 22.54
Golgi lumen 2.239 12.24
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11

Protein sequence

External link(s) Protein: ENSPPYP00000004363   Gene: ENSPPYG00000003814   Transcript: ENSPPYT00000004538
Sequence length 477
Comment pep:known_by_projection chromosome:PPYG2:11:99149070:99156689:-1 gene:ENSPPYG00000003814 transcript:ENSPPYT00000004538 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKSLPILLLLCVAACSAYPLDGAARSEDTSMNLVQKYLENYYDLEKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGQFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPDTPPVPTEPVPPEPGTPAKCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPDLYLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVQAGYPRGIHTLGFPPTVRKIDAAISDNEKKKTYFFVEDKYWRFDEKRNSMEP
GFPKQTAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKNVTHTLKSNSWLNC
Download sequence
Identical sequences H2NF35
ENSPPYP00000004363 9600.ENSPPYP00000004363 ENSPPYP00000004363

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