SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSOCUP00000015428 from Oryctolagus cuniculus 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOCUP00000015428
Domain Number 1 Region: 271-465
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.32e-70
Family Hemopexin-like domain 0.00000000729
Further Details:      
 
Domain Number 2 Region: 101-263
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 4.45e-57
Family Matrix metalloproteases, catalytic domain 0.000000142
Further Details:      
 
Domain Number 3 Region: 20-96
Classification Level Classification E-value
Superfamily PGBD-like 4.71e-21
Family MMP N-terminal domain 0.000095
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
brush border 1.477 22.56
Golgi lumen 2.24 12.25
secretory granule 1.818 10.6
neuron projection terminus 2.132 10.38
lysosomal membrane 1.986 8.14
trans-Golgi network 1.793 7.96
lytic vacuole 1.571 7.43
vacuolar part 1.621 7.24
dendrite 1.585 7.21
transferase complex 1.423 5.58
Molecular Function IC (bits) H-Score
endopeptidase activity 1.536 148.91
metalloendopeptidase activity 2.043 148.91
zinc ion binding 1.65 43.49
integrin binding 1.779 17.72
growth factor receptor binding 1.998 15.09
cytokine receptor binding 2.036 15.09
enzyme activator activity 1.376 14.48
amide binding 1.716 13.08
cell adhesion molecule binding 1.514 11.59
collagen binding 1.844 5.54

Protein sequence

External link(s) Protein: ENSOCUP00000015428   Gene: ENSOCUG00000017958   Transcript: ENSOCUT00000017958
Sequence length 468
Comment pep:known chromosome:OryCun2.0:1:113746997:113756596:1 gene:ENSOCUG00000017958 transcript:ENSOCUT00000017958 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPGLPLLLLLLWGVGSHGFPAASETQEQDVEMVQKYLENYYNLKDDWRKIPKQRGNGLAV
EKLKQMQEFFGLKVTGKPDAETLKMMKQPRCGVPDVAQFVLTPGNPRWEQTHLTYRIENY
TPDLSRADVDNAIEKAFQLWSNVTPLTFTKVSKGQADIMISFVRGDHRDNSPFDGPEGQL
AHAFQPGLGIGGDVHFDEDDRWTKDFRNYNLYRVAAHELGHSLGLSHSTDIGALMYPNYM
FSGDVQLAQDDIDGIQAIYGPSQNPSQPVGPQTPKVCDSKLTFDAITTIRGEIMFFKDRF
YMRANPYYSEVELNFISVFWPHLPNGLQAAYEVAHRDEILFFKGNKYWTVQGQNELPGYP
KDIHSSFGFPRSVNHIDAAVSEEDTGKTYFFVANKYWRYDEYKRSMDAGYPKMIEYDFPG
IGNKVDAVFKKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
Download sequence
Identical sequences P13943
ENSOCUP00000015428

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