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Domain assignment for ENSOCUP00000015428 from Oryctolagus cuniculus 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOCUP00000015428
Domain Number 1 Region: 271-465
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.32e-70
Family Hemopexin-like domain 0.00000000729
Further Details:      
 
Domain Number 2 Region: 101-263
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 4.45e-57
Family Matrix metalloproteases, catalytic domain 0.000000142
Further Details:      
 
Domain Number 3 Region: 20-96
Classification Level Classification E-value
Superfamily PGBD-like 4.71e-21
Family MMP N-terminal domain 0.000095
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSOCUP00000015428   Gene: ENSOCUG00000017958   Transcript: ENSOCUT00000017958
Sequence length 468
Comment pep:known chromosome:OryCun2.0:1:113746997:113756596:1 gene:ENSOCUG00000017958 transcript:ENSOCUT00000017958 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPGLPLLLLLLWGVGSHGFPAASETQEQDVEMVQKYLENYYNLKDDWRKIPKQRGNGLAV
EKLKQMQEFFGLKVTGKPDAETLKMMKQPRCGVPDVAQFVLTPGNPRWEQTHLTYRIENY
TPDLSRADVDNAIEKAFQLWSNVTPLTFTKVSKGQADIMISFVRGDHRDNSPFDGPEGQL
AHAFQPGLGIGGDVHFDEDDRWTKDFRNYNLYRVAAHELGHSLGLSHSTDIGALMYPNYM
FSGDVQLAQDDIDGIQAIYGPSQNPSQPVGPQTPKVCDSKLTFDAITTIRGEIMFFKDRF
YMRANPYYSEVELNFISVFWPHLPNGLQAAYEVAHRDEILFFKGNKYWTVQGQNELPGYP
KDIHSSFGFPRSVNHIDAAVSEEDTGKTYFFVANKYWRYDEYKRSMDAGYPKMIEYDFPG
IGNKVDAVFKKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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Identical sequences P13943
ENSOCUP00000015428

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