SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSOCUP00000015428 from Oryctolagus cuniculus 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOCUP00000015428
Domain Number 1 Region: 271-465
Classification Level Classification E-value
Superfamily Hemopexin-like domain 4.32e-70
Family Hemopexin-like domain 7.29e-09
Further Details:      
 
Domain Number 2 Region: 101-263
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 4.45e-57
Family Matrix metalloproteases, catalytic domain 1.42e-07
Further Details:      
 
Domain Number 3 Region: 20-96
Classification Level Classification E-value
Superfamily PGBD-like 4.71e-21
Family MMP N-terminal domain 9.5e-05
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07
Cellular Component IC (bits) H-Score
brush border 1.48 22.54
Golgi lumen 2.239 12.24
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11

Protein sequence

External link(s) Protein: ENSOCUP00000015428   Gene: ENSOCUG00000017958   Transcript: ENSOCUT00000017958
Sequence length 468
Comment pep:known chromosome:OryCun2.0:1:113746997:113756596:1 gene:ENSOCUG00000017958 transcript:ENSOCUT00000017958 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPGLPLLLLLLWGVGSHGFPAASETQEQDVEMVQKYLENYYNLKDDWRKIPKQRGNGLAV
EKLKQMQEFFGLKVTGKPDAETLKMMKQPRCGVPDVAQFVLTPGNPRWEQTHLTYRIENY
TPDLSRADVDNAIEKAFQLWSNVTPLTFTKVSKGQADIMISFVRGDHRDNSPFDGPEGQL
AHAFQPGLGIGGDVHFDEDDRWTKDFRNYNLYRVAAHELGHSLGLSHSTDIGALMYPNYM
FSGDVQLAQDDIDGIQAIYGPSQNPSQPVGPQTPKVCDSKLTFDAITTIRGEIMFFKDRF
YMRANPYYSEVELNFISVFWPHLPNGLQAAYEVAHRDEILFFKGNKYWTVQGQNELPGYP
KDIHSSFGFPRSVNHIDAAVSEEDTGKTYFFVANKYWRYDEYKRSMDAGYPKMIEYDFPG
IGNKVDAVFKKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
Download sequence
Identical sequences P13943
ENSOCUP00000015428

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