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Domain assignment for ENSOCUP00000023597 from Oryctolagus cuniculus 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOCUP00000023597
Domain Number 1 Region: 282-476
Classification Level Classification E-value
Superfamily Hemopexin-like domain 9.68e-66
Family Hemopexin-like domain 0.00000396
Further Details:      
 
Domain Number 2 Region: 48-241
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.47e-42
Family Matrix metalloproteases, catalytic domain 0.0000455
Further Details:      
 
Domain Number 3 Region: 2-62
Classification Level Classification E-value
Superfamily PGBD-like 1.88e-16
Family MMP N-terminal domain 0.0053
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Golgi lumen 2.224 18.39
cell surface 1.3 10.4
Golgi membrane 1.639 9.22
trans-Golgi network 1.766 9.22
neuron projection terminus 2.125 9.05
exocytic vesicle 2.03 8.34
vacuolar part 1.567 6.28
dendrite 1.582 5.69
host cell part 1.996 5.41
lysosomal membrane 1.946 5.05
Molecular Function IC (bits) H-Score
metallopeptidase activity 2.054 168.98
endopeptidase activity 1.571 151.3
zinc ion binding 1.527 42.04
cytokine receptor binding 1.974 16.02
growth factor receptor binding 2.188 16.02
enzyme activator activity 1.431 14.69
integrin binding 1.56 12.29
fibronectin binding 2.165 10.75
serine hydrolase activity 1.589 10.26
peptide transporter activity 1.665 9.96

Protein sequence

External link(s) Protein: ENSOCUP00000023597   Gene: ENSOCUG00000025473   Transcript: ENSOCUT00000031246
Sequence length 541
Comment pep:known_by_projection scaffold:OryCun2.0:GL019345:51104:63368:-1 gene:ENSOCUG00000025473 transcript:ENSOCUT00000031246 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
EWLSRFGYLPPADSTTGQLQTQEELSKAITAMQQFGGLETTGILDEATLALMKTPRCSLP
DLPPVAQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGRDTVRALMYYTLKVWSDITPL
NFHEMASSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGDHHTAGDTHFDDDEAWTFR
SSDAQGMDLFAVAVHEFGHAIGLGHVAATRSIMRPYYQGPVGDPLRYGLPYEDRVRVWQL
YGVRESVSPTAQPDTPEAEEPPLLPEPPDNRSSTAPRKDVPHRCSTHFDAVAQIRGEAFF
FKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVF
KDNNVEEGYPRPISDFSLPPGGVDAAFSWAHNDRTYFFKGQRYWRYDDHTRRMDPGYPAQ
SPLWRGVPSMLDDAMRWSDGASYFFRGPEYWKVLDGELEAAPGYPQSTARDWLVCGEPQD
EDTEAVGVDRAAQPGQHGQSRSGNSYEVCSCTSHAPPLRAAATLLLLLLLPPSALWTAAR
S
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Identical sequences G1U2J8
ENSOCUP00000023597 9986.ENSOCUP00000023597 ENSOCUP00000023597

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