SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSOCUP00000023597 from Oryctolagus cuniculus 76_2

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOCUP00000023597
Domain Number 1 Region: 282-476
Classification Level Classification E-value
Superfamily Hemopexin-like domain 9.68e-66
Family Hemopexin-like domain 3.96e-06
Further Details:      
 
Domain Number 2 Region: 48-241
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 1.47e-42
Family Matrix metalloproteases, catalytic domain 4.55e-05
Further Details:      
 
Domain Number 3 Region: 2-62
Classification Level Classification E-value
Superfamily PGBD-like 1.88e-16
Family MMP N-terminal domain 0.0053
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.956 173.69
endopeptidase activity 1.539 149.07
zinc ion binding 1.658 43.61
integrin binding 1.752 17.74
cytokine receptor binding 2.034 15.08
growth factor receptor binding 1.996 15.08
enzyme activator activity 1.402 14.46
amide binding 1.71 13.19
collagen binding 1.837 10.43
protein complex binding 1.49 8.1
Cellular Component IC (bits) H-Score
brush border 1.481 22.53
Golgi lumen 2.24 12.28
secretory granule 1.827 10.56
neuron projection terminus 2.132 9.5
lysosomal membrane 2.005 8.2
trans-Golgi network 1.798 8.02
coated vesicle 1.745 7.82
clathrin-coated vesicle 1.877 7.82
dendrite 1.548 7.12
synapse part 1.513 5.74

Protein sequence

External link(s) Protein: ENSOCUP00000023597   Gene: ENSOCUG00000025473   Transcript: ENSOCUT00000031246
Sequence length 541
Comment pep:known_by_projection scaffold:OryCun2.0:GL019345:51104:63368:-1 gene:ENSOCUG00000025473 transcript:ENSOCUT00000031246 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
EWLSRFGYLPPADSTTGQLQTQEELSKAITAMQQFGGLETTGILDEATLALMKTPRCSLP
DLPPVAQARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGRDTVRALMYYTLKVWSDITPL
NFHEMASSAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGDHHTAGDTHFDDDEAWTFR
SSDAQGMDLFAVAVHEFGHAIGLGHVAATRSIMRPYYQGPVGDPLRYGLPYEDRVRVWQL
YGVRESVSPTAQPDTPEAEEPPLLPEPPDNRSSTAPRKDVPHRCSTHFDAVAQIRGEAFF
FKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVF
KDNNVEEGYPRPISDFSLPPGGVDAAFSWAHNDRTYFFKGQRYWRYDDHTRRMDPGYPAQ
SPLWRGVPSMLDDAMRWSDGASYFFRGPEYWKVLDGELEAAPGYPQSTARDWLVCGEPQD
EDTEAVGVDRAAQPGQHGQSRSGNSYEVCSCTSHAPPLRAAATLLLLLLLPPSALWTAAR
S
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Identical sequences G1U2J8
ENSOCUP00000023597 9986.ENSOCUP00000023597 ENSOCUP00000023597

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