SUPERFAMILY 1.75 HMM library and genome assignments server

Domain assignment for ENSOPRP00000003261 from Ochotona princeps 76

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSOPRP00000003261
Domain Number 1 Region: 109-273
Classification Level Classification E-value
Superfamily Metalloproteases ("zincins"), catalytic domain 2.52e-57
Family Matrix metalloproteases, catalytic domain 5.82e-06
Further Details:      
 
Domain Number 2 Region: 292-483
Classification Level Classification E-value
Superfamily Hemopexin-like domain 1.26e-50
Family Hemopexin-like domain 1.17e-05
Further Details:      
 
Domain Number 3 Region: 27-105
Classification Level Classification E-value
Superfamily PGBD-like 9.58e-19
Family MMP N-terminal domain 0.00068
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
metallopeptidase activity 1.957 173.75
endopeptidase activity 1.54 149.12
zinc ion binding 1.659 43.58
integrin binding 1.753 17.75
cytokine receptor binding 2.035 15.08
growth factor receptor binding 1.997 15.08
enzyme activator activity 1.401 14.47
amide binding 1.711 13.09
collagen binding 1.838 10.43
protein complex binding 1.491 8.07
Cellular Component IC (bits) H-Score
brush border 1.48 22.54
Golgi lumen 2.239 12.24
secretory granule 1.826 10.6
neuron projection terminus 2.106 10.52
lysosomal membrane 1.998 8.25
trans-Golgi network 1.797 7.99
coated vesicle 1.74 7.78
clathrin-coated vesicle 1.876 7.78
lytic vacuole 1.57 7.42
vacuolar part 1.621 7.11

Protein sequence

External link(s) Protein: ENSOPRP00000003261   Gene: ENSOPRG00000003551   Transcript: ENSOPRT00000003549
Sequence length 483
Comment pep:known_by_projection genescaffold:pika:GeneScaffold_2354:271142:306279:-1 gene:ENSOPRG00000003551 transcript:ENSOPRT00000003549 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MKVLPASGLAVFLIMALKFSAAAPSLFTATPRTWRNNFHLAQAYLDKYYTKKGGTQVGEM
VARGGNAMVKKIKELQAFFGLQVTGKLDQNTMDVIKKPRCGVPDVANYRLFPGEPKWKKN
TLTYRVSKYTSSMAPVEVDKAVEMALRAWSSAVPLNFVRVNTGEADIMISFETGDHGDSY
PFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDP
TALMYPTYKYQNPYGFHLPKDDVRGIQALYGPRKPFLGKPTLPHIPPHKPILPDLCDSSS
SFDAVTMLGKELLFFRDRIFWRRQLHLPTGVQPSTITSSFPQLMSNVDAAYEVAERGTAY
FFKGPHYWVTRGFQMQGSPRTIYDXXXXXXXXXXXXXXXLKEPQKTLFFVGDEYYSFDEQ
KRKMEKDYPKSIEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVMKSNSW
IGC
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Identical sequences ENSOPRP00000003261 ENSOPRP00000003261

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